Дисертації з теми "Laser desorption/ laser ionization"
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Rogers, Kevin Shaun. "Laser desorption/laser ionization mass spectroscopy." Thesis, University of Salford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357037.
Clipston, Nigel L. "Laser desorption/laser ionization Time-of-Flight Mass Spectrometry." Thesis, University of Salford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360476.
Wen, Xiujuan. "Small Molecule Matrix-free Laser Desorption/ionization Mass Spectrometry." Thesis, The University of Arizona, 2006. http://hdl.handle.net/10150/193332.
Lu, Tian. "Nanomaterials For Liquid Chromatography and Laser Desorption/Ionization MassSpectrometry." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1376981440.
Peng, Ivory Xingyu. "Electrospray-assisted laser desorption ionization mass spectrometry for proteomic studies." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1997571271&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Berhane, Beniam T. "Rapid Characterization of Posttranscriptional Modifications in RNA Using Matrix Assisted Laser Desorption Ionization Mass Spectrometry and Matrix Assisted Laser Desorption Ionization Post Source Decay Mass Spectrometry." University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1052319621.
Dubois, Frédéric Dubois Frédéric. "Ion formation and detection in matrix-assisted laser desorption/ionization mass spectrometry /." [S.l.] : [s.n.], 1999. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13255.
Dai, Yuqin. "Development of matrix-assisted laser desorption ionization mass spectrometry for biopolymer analysis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0003/NQ39519.pdf.
Shariatgorji, Mohammadreza. "Novel clean-up, concentration and laser desorption/ionization strategies for mass spectrometry /." Stockholm : Department of Analytical Chemistry, Stockholm University, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-32236.
At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 3: In Press. Härtill 7 uppsatser.
Tummala, Manorama. "Surfactant-Aided Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (SA-MALDI MS)." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1100672049.
Astorga-Wells, Juan. "Microfluidic electrocapture technology in protein and peptide analysis /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-965-x/.
Dashtiev, Maxim. "Fluorescence spectroscopy of trapped molecular ions produced with matrix-assisted laser desorption/ionization /." Zürich : ETH, 2006. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=16949.
Zhang, Hui. "Developments and applications of electrophoresis and small molecule laser desorption ionization mass spectrometry." [Ames, Iowa : Iowa State University], 2007.
Segu, Mohideen Mohamed Zaneer. "TARGET MODIFICATION FOR ENHANCED PERFORMANCE MATRIX ASSISTED LASER DESORPTION IONIZATION (MALDI) MASS SPECTROMETRY." Available to subscribers only, 2008. http://proquest.umi.com/pqdweb?did=1674093101&sid=1&Fmt=2&clientId=1509&RQT=309&VName=PQD.
"Department of Chemistry." Keywords: Enhanced MALDI, MALDI-MS, On-probe separation, Protein-surface interactions, Sublayers, Surface binding capacity. Includes bibliographical references (p. 130-148). Also available online.
Akinapalli, Srikanth. "MICROFLUIDIC DYNAMIC ISOELECTRIC FOCUSING COUPLED TO MATRIX ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY." OpenSIUC, 2016. https://opensiuc.lib.siu.edu/dissertations/1289.
Xiang, Fan. "Improvement and investigation of sample preparation for matrix-assisted laser desorption/ionization of proteins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq25780.pdf.
Wang, Jian. "Analyses of food and feed compounds using matrix-assisted laser desorption/ionization mass spectrometry." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0013/NQ59690.pdf.
Liu, Qiang. "Fundamental Study and Method Development for Surface-based Laser Desorption Ionization Imaging Mass Spectrometry." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-02262009-143514/.
Busse, Frederik [Verfasser], and R. J. Dwayne [Akademischer Betreuer] Miller. "Mechanisms of Picosecond Infrared Laser Desorption Ionization / Frederik Busse ; Betreuer: R. J. Dwayne Miller." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2019. http://d-nb.info/1192912977/34.
Mowat, Ian A. "Synthetic polymer analysis using matrix assisted laser desorption/ionization time-of-flight mass spectrometry." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/12128.
Garrett, Timothy J. "Imaging small molecules in tissue by matrix-assisted laser desorption/ionization tandem mass spectrometry." [Gainesville, Fla.] : University of Florida, 2006. http://purl.fcla.edu/fcla/etd/UFE0013807.
Köchling, Heinrich J. (Heinrich Josef) 1962. "Advancements in matrix-assisted laser desorption ionization mass spectrometry of peptides, proteins and polymers." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/10020.
Priyasantha, Kandalama KD. "DEVELOPMENT OF A NOVEL MATRIX ASSISTED LASER DESORPTION / IONIZATION (MALDI) BASED PEPTIDE QUANTITATION APPROACH." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/989.
Mazarin, Michaël. "L'ionisation MALDI [Matrix assisted laser desorption/ionization] de polymères synthétiques en spectrométrie de masse." Aix-Marseille 1, 2008. http://theses.univ-amu.fr.lama.univ-amu.fr/2008AIX11034.pdf.
Matrix assisted laser desorption/ionization (MALDI) mass spectrometry is a key technique for synthetic polymer structural characterization. Nevertheless, because fundamental process of MALDI is still not fully understood, no standard protocol is available and experimental conditions are empirically optimized. The aim of this PhD work is to combine mass spectrometric techniques with nuclear magnetic resonance (NMR) spectroscopies to develop rationalized MALDI methodologies for structural studies of synthetic polymers. A first approach consists of using diffusion NMR for a rapid evaluation of polymer average mass, to be further used as a guideline in MALDI sample preparation and spectral data interpretation. A second axis deals with fragile end-groups of macromolecules synthesized via controlled radical polymerization reactions. Combining collision-induced dissociation of electrosprayed oligomers with liquid state NMR and theoretical calculations allowed the elucidation of mechanisms involved in the bond cleavage which is observed to occur within such end-groups during the MALDI process. This study shows that protonation of the fragile termination is the main way to allow intact oligomer ions to be produced. A solvent-free MALDI sample preparation was thus developed to promote macromolecule protonation but its efficiency was shown to be limited to the case of small polymers. Finally, the potential of solid state NMR to characterize the microstructure of MALDI sample was evaluated
Erb, William Joseph Owens Kevin G. "Exploration of the fundamentals of matrix assisted laser desorption/ionization time-of- flight mass spectrometry /." Philadelphia, Pa. : Drexel University, 2007. http://hdl.handle.net/1860/1765.
Tang, Ho-wai, and 鄧浩維. "Studies on surface-assisted laser desorption/ionization and its analytical application in imaging mass spectrometry." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47145559.
published_or_final_version
Chemistry
Doctoral
Doctor of Philosophy
Fiorentino, Michael Armond. "Immediate observation of matrix assisted laser desorption ionization products in a Fourier transform mass spectrometer /." Full text (PDF) from UMI/Dissertation Abstracts International, 2000. http://wwwlib.umi.com/cr/utexas/fullcit?p3004264.
Moyer, Susanne Catharine. "Phosphotyrosine peptide fragmentation by atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry." Available to US Hopkins community, 2002. http://wwwlib.umi.com/dissertations/dlnow/3080729.
An, Hyun Joo. "Characterization of protein-bound oligosaccharides using matrix-assisted laser desorption/ionization Fourier transform mass spectrometry /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.
Stumpo, Katherine Anne. "Size-selected 2, 5, and 10 nm gold nanoparticles for laser desorption/ionization mass spectrometry." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3127.
Smith, Donna M. "Matrix Assisted Laser Desorption Ionization Quadrupole Time-of-Flight Mass Spectrometry of Poly(2-Vinylpyridine)." University of Akron / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=akron1110337309.
Watson, R. Craig Jr. "Laser-Ionization Time-of-Flight Mass Spectrometry of High Molecular Mass Inorganic Complexes." Thesis, Virginia Tech, 1997. http://hdl.handle.net/10919/35554.
This thesis describes the characterization of a LI-TOF-MS instrument and confirmation of theoretical time-of-flight mass-separation principles. Several test cases demonstrate the instrument's proper operation and calibration for a wide mass range of analytes. Mass spectral results of three organometallic compounds: i. [Ir(dpp)2Cl2](PF6), ii. {[(bpy)2Ru(dpp)]2IrCl2}(PF6)5, and iii. {[(bpy)2Ru(dpp)]2RuCl2}(PF6)5 under a variety of laser ionization and sample preparation conditions are compared. A complete structural characterization of the monometallic complex, [Ir(dpp)2Cl2](PF6), is presented. The two trimetallic analytes fragmented easily, but significant components of the molecules are successfully identified. After optimizing the ionization and analytical procedure, LI-TOF-MS proved useful in the analysis of high molecular mass metal complexes.
Master of Science
Hongming, Guo. "IMPROVING MATRIX DEPOSITION FOR SURFACE LAYER MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY IMAGING (SL-MALDI-TOF MSI)." University of Akron / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=akron155654549756264.
Hoteling, Andrew J. "MALD/I TOF PSD and CID : understanding precision, resolution, and mass accuracy and MALD/I TOFMS : investigation of discrimination issues related to solubility /." Philadelphia, Pa. : Drexel University, 2004. http://dspace.library.drexel.edu/handle/1860/318.
Zhang, Jinhua. "Characterization and structural elucidation of oligosaccharides by matrix-assisted laser desorption/ionization Fourier transform mass spectrometry /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.
SUH, MOO-JIN. "MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY OF BACTERIAL RIBOSOMAL PROTEINS AND RIBOSOMES." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1106583486.
Ochoa, Mariela L. "Forensic and Proteomic Applications of Thermal Desorption Ion Mobility Spectrometry and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry." Ohio University / OhioLINK, 2005. http://www.ohiolink.edu/etd/view.cgi?ohiou1113585811.
Krutchinsky, Andrew. "A collisional damping interface for a time-of-flight mass spectrometer with both electrospray ionization and matrix assisted laser desorption ionization." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0009/NQ31999.pdf.
Yao, Mengmeng. "Determining Polymer Blend Surface Concentration Using Surface Layer Matrix-Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (SL-MALDI-TOF MS)." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1407941345.
Hill, Jacob A. Hill. "SURFACE LAYER MATRIX-ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY (SL-MALDI-TOF MS) ANALYSIS OF POLYMER BLEND SURFACE COMPOSITION." University of Akron / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=akron1514479406062149.
Chen, Yanfeng. "Analysis of Biological Molecules Using Stimulated Desorption Photoionization Mass Spectrometry." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/14620.
Robins, Chad LaJuan. "Nonpolar matrices for matrix assisted laser desportion ionization - time of flight - mass spectrometry." Cincinnati, Ohio : University of Cincinnati, 2005. http://www.ohiolink.edu/etd/view.cgi?acc%5Fnum=ucin1115293526.
Title from electronic thesis title page (viewed May 18, 2006). Includes abstract. Keywords: Matrix Assisted Laser Desorption/Ionization Mass Spectrometry; MALDI; Nonpolar Matrices; Charge-Transfer Ionization; Crude Oil; Mass Spectrometry. Includes bibliographical references.
Siricord, Cornelia Charito. "Detection of Phytophthora species by MALDI-TOF mass spectrometry." Siricord, Cornelia Charito (2005) Detection of Phytophthora species by MALDI-TOF mass spectrometry. PhD thesis, Murdoch University, 2005. http://researchrepository.murdoch.edu.au/314/.
Holcomb, April M. Owens Kevin G. "Investigation into the ionization mechanism occurring in matrix assisted laser desorption ionization and factors affecting ion flight time in MALDI time-of-flight mass spectrometry /." Philadelphia, Pa. : Drexel University, 2009. http://hdl.handle.net/1860/3161.
Emanuele, Vincent A. II. "Advancements in high throughput protein profiling using surface enhanced laser desorption/ionization time of flight mass spectrometry." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37287.
Abell, Darcy Cameron. "Analysis of potato glycoalkaloids by ELISA and matrix assisted laser desorption/ionization time-of-flight mass spectroscopy /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq22940.pdf.
Wu, Li-Chieh, and 吳俐節. "Development of thin layer chromatography/electrospray laser desorption ionization mass spectrometry and its applications." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/13603098618638216212.
Liou, Jhao-Yan, and 劉昭延. "Development and Applications of Thermo Desorption and Laser Desorption Electrospray Ionization Mass Spectrometry." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/q8kt9r.
國立中山大學
化學系研究所
107
With the rapid development of ambient mass spectrometry (AMS), different functions of ambient ionization have also been reported. Based on the different sampling/desorption methods, AMS can be classified as thermal desorption, laser desorption, and gas stream methods. Thermal desorption was used to characterize volatile or semi-volatile compounds in liquid or solid samples, while laser desorption was applied to detect non-volatile samples. The method of gas stream was developed to determine volatile and thermally unstable compounds in solution. The purpose of this thesis is to develop a new ambient ionization technique called thermal desorption and laser desorption electrospray ionization mass spectrometry (LD+TD-ESI/MS), which is capable of analyzing polymer materials and alkaloids in plants. Thermal desorption and laser desorption electrospray ionization mass spectrometry comprised a continuous infrared laser device, a copper tube heating device, a temperature controlled nitrogen stream device and an electrospray ionization device. Since the ion source provided high power for laser desorption, thermally stable to be heated, and temperature-controlled auxiliary to transfer analytes, the system can be simultaneously detected non-volatile and volatile analytes. Herein, the ionization mechanism will be explained in detail and performances related to instrumentation will also be optimized, including its repeatability, reproducibility, sensitivity, and robust procedure. In the second part, LD+TD-ESI/MS was used for direct analysis of the polymer materials. Firstly, a complete database of polymer material was established. Various plastic products commonly used in daily life were directly analyzed. The resultant polymers, in addition to additives of the samples, were rapidly characterized. In addition, LD+TD-ESI/MS can also detect alkaloids. In potato with sprouts, the signals of both α-chaconine and α-solanine can be detected. According to the previous literature, potatoes contain toxic compounds known as glycoalkaloids, of which the most prevalent are α-chaconine and α-solanine. It is pointed out that α-chaconine and α-solanine account for more than 95% of the total amount of glycoalkaloids. Additionally, they cann’t be decomposed by heating. Once the excessive intake of glycoalkaloids is in danger of acute poisoning. Thus, the rapid identification of glycoalkaloids will help prevent the recurrence of such poisoning tragedies.
Hong, Hui Min, and 洪惠敏. "The study of metal complex salts in laser desorption ionization." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/25823194337932205675.
Ovchinnikova, Olga Sergeevna. "Spatially Resolved Laser and Thermal Desorption/Ionization Coupled with Mass Spectrometry." 2011. http://trace.tennessee.edu/utk_graddiss/1112.