Добірка наукової літератури з теми "S-NO-HSA"

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Статті в журналах з теми "S-NO-HSA"

1

Tsiountsioura, Melina, Gerhard Cvirn, Axel Schlagenhauf, et al. "The Antiplatelet Action of S-Nitroso Human Serum Albumin in Whole Blood." Biomedicines 10, no. 3 (2022): 649. http://dx.doi.org/10.3390/biomedicines10030649.

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Nitric oxide donors (NO-donors) have been shown to have therapeutic potential (e.g., ischemia/reperfusion injury). However, due to their release rate/antiplatelet properties, they may cause bleeding in patients. We therefore studied the antiplatelet effects of the two different NO-donors, i.e., S-NO-Human Serum Albumin (S-NO-HSA) and Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate (DEA-NONOate) in whole blood (WB) samples. WB samples were spiked with S-NO-HSA or DEA-NONOate (100 µmol/L or 200 µmol/L), and the NO release rate (nitrite/nitrate levels via HPLC) and antiplatelet e
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2

Jakubovics, Nicholas S., Steven W. Kerrigan, Angela H. Nobbs, et al. "Functions of Cell Surface-Anchored Antigen I/II Family and Hsa Polypeptides in Interactions of Streptococcus gordonii with Host Receptors." Infection and Immunity 73, no. 10 (2005): 6629–38. http://dx.doi.org/10.1128/iai.73.10.6629-6638.2005.

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ABSTRACT Streptococcus gordonii colonizes multiple sites within the human oral cavity. This colonization depends upon the initial interactions of streptococcal adhesins with host receptors. The adhesins that bind salivary agglutinin glycoprotein (gp340) and human cell surface receptors include the antigen I/II (AgI/II) family polypeptides SspA and SspB and a sialic acid-binding surface protein designated Hsa or GspB. In this study we determined the relative functions of the AgI/II polypeptides and Hsa in interactions of S. gordonii DL1 (Challis) with host receptors. For an isogenic mutant with
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3

Nakajima, G., K. Uchida, K. Hayashi, Y. Xi, K. Takasaki, and J. Ju. "Non-coding microRNA hsa-let-7g as a novel chemoresponse biomarker for S-1 in colon cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 13513. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.13513.

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13513 Background: MicroRNAs (miRNAs) are small non-cording RNAs (∼ 22 nucleotide) that regulate gene expression by suppressing their target mRNAs at post-transcriptional level. Previous studies from our group have identified a number of dis-regulated miRNAs due to the loss of p53 tumor suppressor in cancer cell lines. As part of the efforts to further investigate the in vivo biological significance of these miRNAs, the expression of both hsa-let-7g and hsa-miR-200c were investigated using formalin-fixed paraffin embedded (FFPE) colon cancer specimens to evaluate the potential correlation with
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4

Rogóż, Wojciech, Jadwiga Pożycka, Aleksandra Owczarzy, Karolina Kulig, and Małgorzata Maciążek-Jurczyk. "Comparison of Losartan and Furosemide Interaction with HSA and Their Influence on HSA Antioxidant Potential." Pharmaceuticals 15, no. 5 (2022): 499. http://dx.doi.org/10.3390/ph15050499.

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Serum albumin (HSA) is the most important protein in human body. Due to the antioxidant activity, HSA influences homeostasis maintenance and transport of drugs as well as other substances. It is noteworthy that ligands, such as popular drugs, modulate the antioxidant activity of HSA. The aim of this study was to analyze the influence of losartan (LOS) and furosemide (FUR) on HSA antioxidant properties as well as the interaction between these drugs and protein using calorimetric and spectroscopic methods. LOS and FUR showed the high affinity for human serum albumin, and the binding reactions be
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5

Neumayer, C., A. Fügl, J. Nanobashvili, et al. "S-NITROSO HUMAN SERUM ALBUMIN (S-NO-HSA) REDUCES ISCHEMIA/REPERFUSION INJURY OF SKELETAL MUSCLE - HISTOMORPHOMETRIC ASPECTS." Shock 12, Supplement (1999): 58–59. http://dx.doi.org/10.1097/00024382-199911001-00182.

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6

Kerrigan, Steven W., Nick S. Jakubouvics, Gerardene Meade, Howard F. Jenkinson та Dermot M. Cox. "A Novel GPIbα Binding Protein on Streptococcus Gordonii Induces Platelet Rolling at Low Shear." Blood 104, № 11 (2004): 3663. http://dx.doi.org/10.1182/blood.v104.11.3663.3663.

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Abstract Infective endocarditis is associated with considerable morbidity and mortality and oral Streptococci are the priniciple causative organism. Platelet adhesion and subsequent aggregation play a critical role in the pathogenesis and dissemination of the infective process. The mechanism by which S. gordonii interacts with and subsequently leads to platelet activation is currently unknown. Previously we described the ability of Streptococcus sanguis to induce platelet aggregation via the platelet vonWillebrand factor receptor, GPIbα, however identification of the bacterial protein involved
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7

Mahata, Shibendu, Suman Kumar Saha, Rajib Kar, Durbadal Mandal, and Nilotpal Banerjee. "A Heuristic Approach to Design Discrete Fractional Order Integrators without Using s-to-z Transform." Solid State Phenomena 261 (August 2017): 386–93. http://dx.doi.org/10.4028/www.scientific.net/ssp.261.386.

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In this paper, a heuristic optimization technique called Harmony Search Algorithm (HSA) is efficiently employed to design Infinite Impulse Response (IIR) Discrete Fractional Order Integrators (DFOIs). Unlike the methods reported in the literature, no discretization (s-to-z transform) operator is necessary to obtain the DFOIs by using the proposed approach. To investigate the design efficiency, the HSA-based DFOIs have been evaluated against the designs based on Real coded Genetic Algorithm (RGA), Particle Swarm Optimization (PSO), and Differential Evolution (DE) using different frequency respo
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8

Bahlis, Nizar J., Carolyn J. Owen, Paola Neri, et al. "A miRNA Risk Score for the Prediction of Response to Rituximab-CHOP Therapy and Survival of Patients with Diffuse Large B-Cell Lymphoma." Blood 116, no. 21 (2010): 324. http://dx.doi.org/10.1182/blood.v116.21.324.324.

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Abstract Abstract 324 Background: Diffuse large B-cell lymphoma (DLBCL) may be curable with current immuno-chemotherapy, however nearly 30% of patients fail to benefit from this therapeutic approach. Gene expression profiling studies identified lymphocyte as well as stroma-based mRNA signatures that are predictive of response to R-CHOP; however the need for optimally cryopreserved samples has limited their clinical applicability. MicroRNAs (miRNA) are highly preserved non-coding RNAs that act post-transcriptionally to regulate gene expression by binding to the 3′UTR of mRNAs. To date multiple
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9

Rungatscher, A., S. Hallström, D. Linardi, et al. "595 Cardioprotective Effects of S-Nitroso Human Serum Albumin (S-NO-HSA) during Cardioplegic Arrest and Cold Storage in a Working Heart Heterotopic Transplant Model." Journal of Heart and Lung Transplantation 30, no. 4 (2011): S199—S200. http://dx.doi.org/10.1016/j.healun.2011.01.607.

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10

Lodi, Tiziana, Barbara Neglia, and Claudia Donnini. "Secretion of Human Serum Albumin by Kluyveromyces lactis Overexpressing KlPDI1 and KlERO1." Applied and Environmental Microbiology 71, no. 8 (2005): 4359–63. http://dx.doi.org/10.1128/aem.71.8.4359-4363.2005.

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ABSTRACT The control of protein conformation during translocation through the endoplasmic reticulum is often a bottleneck for heterologous protein production. The core pathway of the oxidative folding machinery includes two conserved proteins: Pdi1p and Ero1p. We increased the dosage of the genes encoding these proteins in the yeast Kluyveromyces lactis and evaluated the secretion of heterologous proteins. KlERO1, an orthologue of Saccharomyces cerevisiae ERO1, was cloned by functional complementation of the ts phenotype of an Scero1 mutant. The expression of KlERO1 was induced by treatment of
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