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1

Morrell, N., M. M. Phillips, G. Folatelli, et al. "Optical Spectroscopy of Type Ia Supernovae by the Carnegie Supernova Projects I and II." Astrophysical Journal 967, no. 1 (2024): 20. http://dx.doi.org/10.3847/1538-4357/ad38af.

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Abstract We present the second and final release of optical spectroscopy of Type Ia supernovae (SNe Ia) obtained during the first and second phases of the Carnegie Supernova Project (CSP-I and CSP-II). The newly released data consist of 148 spectra of 30 SNe Ia observed in the course of CSP-I and 234 spectra of 127 SNe Ia obtained during CSP-II. We also present 216 optical spectra of 46 historical SNe Ia, including 53 spectra of 30 SNe Ia observed by the Calán/Tololo Supernova Survey. We combine these observations with previously published CSP data and publicly available spectra to compile a l
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2

Beeskow, Anne Bettina, Holger Gößmann, Hans-Jonas Meyer, et al. "Comparison of CT-Guided Microwave Ablation of Liver Malignancies with and Without Intra-Arterial Catheter Placement for Contrast Administration." Current Oncology 32, no. 1 (2025): 28. https://doi.org/10.3390/curroncol32010028.

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Background: The aim of this study was to compare microwave ablation (MWA) with and without prior placement of an intra-arterial catheter for the purpose of application of contrast medium (CM). Methods: 148 patients (45 female, 65.1 ± 14.9 years) with liver tumors who underwent CT-guided MWA were included. Of these, 25 patients had an IA catheter placed in the hepatic artery. Results: 37 patients underwent planning imaging for MWA without CM. A total of 86 patients received a standard dose of 80 mL intravenous (IV) CM for the planning scans. The patients with an IA catheter (n = 25) received an
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González Jaimes, Norma Lilia, Adrían Alejandro Tejeda Alcántara, and Eduardo Quintín Fernández. "Indicadores antropométricos y estilos de vida relacionados con el índice aterogénico en población adulta." CIENCIA ergo sum 27, no. 1 (2019): e74. http://dx.doi.org/10.30878/ces.v27n1a6.

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Se determinan los indicadores antropométricos relacionados significativamente con el índice aterogénico (IA) considerando estilos de vida (sedentarismo, promedio de consumo de calorías/día y tabaquismo), edad y sexo en una población adulta, en apariencia sana, adscrita a un hospital de salud pública de México. Método: estudio transversal-observacional. Muestra por conveniencia: N = 206 (148 mujeres y 58 hombres). Análisis estadísticos: correlacionales y regresión logística binaria utilizando SPSS-19. Resultados y conclusiones: se encuentra una relación significativa entre el incremento de todo
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Chen, Ping, Subo Dong, C. S. Kochanek, et al. "The First Data Release of CNIa0.02—A Complete Nearby (Redshift <0.02) Sample of Type Ia Supernova Light Curves*." Astrophysical Journal Supplement Series 259, no. 2 (2022): 53. http://dx.doi.org/10.3847/1538-4365/ac50b7.

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Abstract The CNIa0.02 project aims to collect a complete, nearby sample of Type Ia supernovae (SNe Ia) light curves, and the SNe are volume-limited with host-galaxy redshifts z host &lt; 0.02. The main scientific goal is to infer the distributions of key properties (e.g., the luminosity function) of local SNe Ia in a complete and unbiased fashion in order to study SN explosion physics. We spectroscopically classify any SN candidate detected by the All-Sky Automated Survey for Supernovae (ASAS-SN) that reaches a peak brightness &lt;16.5 mag. Since ASAS-SN scans the full sky and does not target
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Valle, Guilherme Ribeiro, José Monteiro da Silva Filho, Maristela Silveira Palhares, Ivan Barbosa Machado Sampaio, Henrique Nunes de Oliveira, and José Eduardo Valle Santos. "Efeito do número de inseminações artificiais sobre a fertilidade de éguas inseminadas com sêmen diluído, resfriado a 14ºC e transportado." Revista Brasileira de Zootecnia 29, no. 6 (2000): 1721–26. http://dx.doi.org/10.1590/s1516-35982000000600018.

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Estudou-se o efeito do número de inseminações sobre a fertilidade de éguas inseminadas, três vezes/semana (segundas, quartas e sextas-feiras), com sêmen diluído, resfriado e transportado, de apenas um garanhão. As éguas foram inseminadas a partir da detecção, pela palpação retal, de um folículo de 3,0 a 3,5 cm de diâmetro, em um dos ovários, até a ovulação. Utilizaram-se para o transporte o sêmen diluído no diluidor leite desnatado-glicose e o conteiner "Celle" modificado, sendo a dose inseminante de 400 x 10(6) espermatozóides móveis, no momento da diluição final, pré-resfriamento. De acordo
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SIBBITT, WILMER L., ANDRES PEISAJOVICH, ADRIAN A. MICHAEL, et al. "Does Sonographic Needle Guidance Affect the Clinical Outcome of Intraarticular Injections?" Journal of Rheumatology 36, no. 9 (2009): 1892–902. http://dx.doi.org/10.3899/jrheum.090013.

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Objective.This randomized controlled study addressed whether sonographic needle guidance affected clinical outcomes of intraarticular (IA) joint injections.Methods.In total, 148 painful joints were randomized to IA triamcinolone acetonide injection by conventional palpation-guided anatomic injection or sonographic image-guided injection enhanced with a one-handed control syringe (the reciprocating device). A one-needle, 2-syringe technique was used, where the first syringe was used to introduce the needle, aspirate any effusion, and anesthetize and dilate the IA space with lidocaine. After IA
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Preib, Madison T., Fanny S. Mitrani-Gold, Ziyu Lan, Xiaoxi Sun, and Ashish V. Joshi. "1358. A Real-World Study of the Burden of Illness and Treatment Patterns Among Patients with Uncomplicated Urogenital Gonorrhea in the United States." Open Forum Infectious Diseases 8, Supplement_1 (2021): S765—S766. http://dx.doi.org/10.1093/ofid/ofab466.1550.

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Abstract Background Gonorrhea (GC) is a major public health threat in the US. The Centers for Disease Control and Prevention (CDC) estimated direct healthcare costs of &amp;271 million in 2018. CDC 2015 guidelines (applicable up to December 18, 2020) recommended cephalosporin plus azithromycin for GC. We used real-world data to assess patterns of inappropriate or suboptimal (IA/SO) or appropriate and optimal (AP&amp;OP) antibiotic (AB) prescription (by CDC 2015 guidelines), and related healthcare costs, in US patients with uncomplicated urogenital GC (uUGG) diagnosed from July 1, 2013–June 30,
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Kieran, Emily A., Anne O’Sullivan, Jan Miletin, Anne R. Twomey, Susan J. Knowles, and Colm Patrick Finbarr O’Donnell. "2% chlorhexidine–70% isopropyl alcohol versus 10% povidone–iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial." Archives of Disease in Childhood - Fetal and Neonatal Edition 103, no. 2 (2017): F101—F106. http://dx.doi.org/10.1136/archdischild-2016-312193.

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ObjectiveTo determine whether 2% chlorhexidine gluconate–70% isopropyl alcohol (CHX–IA) is superior to 10% aqueous povidone–iodine (PI) in preventing catheter-related blood stream infection (CR-BSI) when used to clean insertion sites before placing central venous catheters (CVCs) in preterm infants.DesignRandomised controlled trial.SettingTwo neonatal intensive care units (NICUs).PatientsInfants &lt;31 weeks’ gestation who had a CVC inserted.InterventionsInsertion site was cleaned with CHX–IA or PI. Caregivers were not masked to group assignment.Main outcome measuresPrimary outcome was CR-BSI
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Camacho-Neves, Yssavo, Saurabh W. Jha, Barnabas Barna, et al. "Over 500 Days in the Life of the Photosphere of the Type Iax Supernova SN 2014dt." Astrophysical Journal 951, no. 1 (2023): 67. http://dx.doi.org/10.3847/1538-4357/acd558.

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Abstract Type Iax supernovae (SNe Iax) are the largest known class of peculiar white dwarf SNe, distinct from normal Type Ia supernovae (SNe Ia). The unique properties of SNe Iax, especially their strong photospheric lines out to extremely late times, allow us to model their optical spectra and derive the physical parameters of the long-lasting photosphere. We present an extensive spectral timeseries, including 21 new spectra, of SN Iax 2014dt from +11 to +562 days after maximum light. We are able to reproduce the entire timeseries with a self-consistent, nearly unaltered deflagration explosio
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Varble, Nicole, Gabriel Trylesinski, Jianping Xiang, Kenneth Snyder, and Hui Meng. "Identification of vortex structures in a cohort of 204 intracranial aneurysms." Journal of The Royal Society Interface 14, no. 130 (2017): 20170021. http://dx.doi.org/10.1098/rsif.2017.0021.

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An intracranial aneurysm (IA) is a cerebrovascular pathology that can lead to death or disability if ruptured. Abnormal wall shear stress (WSS) has been associated with IA growth and rupture, but little is known about the underlying flow physics related to rupture-prone IAs. Previous studies, based on analysis of a few aneurysms or partial views of three-dimensional vortex structures, suggest that rupture is associated with complex vortical flow inside IAs. To further elucidate the relevance of vortical flow in aneurysm pathophysiology, we studied 204 patient IAs (56 ruptured and 148 unrupture
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Hall, Nigel J., Melanie Drewett, and David Burge. "Nutritional role of amniotic fluid: clues from infants with congenital obstruction of the digestive tract." Archives of Disease in Childhood - Fetal and Neonatal Edition 104, no. 2 (2018): F199—F201. http://dx.doi.org/10.1136/archdischild-2017-314531.

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AimsTo investigate the role played by amniotic fluid in late fetal nutrition by analysis of infants born with digestive tract atresia.MethodsBirth weight (BW), gestational age and gender of infants born with oesophageal (OA), duodenal (DA), jejunal (JA) and ileal atresia (IA) were recorded and BW Z-scores compared. Infants with incomplete obstruction (stenosis), chromosomal or syndromic conditions and multiple congenital malformations were excluded. Term infants admitted with suspected postnatal intestinal obstruction in whom no congenital malformation was found were used as a control group.Re
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Gosselink, K. L., R. R. Roy, H. Zhong, R. E. Grindeland, A. J. Bigbee, and V. R. Edgerton. "Vibration-induced activation of muscle afferents modulates bioassayable growth hormone release." Journal of Applied Physiology 96, no. 6 (2004): 2097–102. http://dx.doi.org/10.1152/japplphysiol.00855.2003.

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The effects of tendon vibration on bioassayable growth hormone (BGH) secretion from the pituitary gland were investigated in anesthetized adult male rats. The tendons from predominantly fast-twitch ankle extensor muscles (gastrocnemius and plantaris) or a predominantly slow-twitch ankle extensor (soleus) were vibrated by using a paradigm that selectively activates group Ia afferent fibers from muscle spindles. The lower hindlimb was secured with the muscles near physiological length, and the tendons were vibrated for 15 min at 150 Hz and a displacement of 1 mm. Control rats were prepared simil
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Wouters, F., E. Niemantsverdriet, N. Salioska, A. L. Dorjée, R. Toes, and A. Van der Helm - van Mil. "THU0064 ANTIBODY-RESPONSE MATURATION IN THE PHASE OF CLINICALLY SUSPECT ARTHRALGIA AND ITS RELATION WITH PROGRESSION TO RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 244.2–245. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3217.

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Background:Auto-antibodies in rheumatoid arthritis (RA) are often present years before disease onset but their mere presence does not seem enough to induce RA. Because several nested-case control studies have shown that autoantibody-response maturation precedes disease onset, it is suggested that it plays a role in disease triggering. At present, it is undetermined whether autoantibody-response maturation occurs in the symptomatic phase preceding clinical arthritis (i.e. Clinically Suspect Arthralgia, CSA), or whether it occurs even earlier in the asymptomatic phase. Secondly, if autoantibody-
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Li, Junmin, Yunxiang Zhang, Qiusheng Chen, et al. "Optimization of IA Regimen with Homoharringtonine for Induction in Younger AML Based on Peripheral Blast Clearance Rate: First Result of the RJ-AML 2014 Trial." Blood 128, no. 22 (2016): 3990. http://dx.doi.org/10.1182/blood.v128.22.3990.3990.

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Abstract Background: Combination of idarubicin and cytarabine (IA) is now the basis of induction treatment for acute myeloid leukemia (AML) while the complete remission (CR) rate is only 60-75%. Homoharringtonine (HHT) based regimen was proved to be an option for AML and may improve long-term survival [1]. As previously reported, we established an effective evaluation of early treatment response by monitoring peripheral blast through flow cytometry, and concluded that patient with Day 5 peripheral blast clearance rate &lt; 99.55% (D5-PBCR +) carries poor prognosis [2]. Thus we designed clinica
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Wang, Yi-Han, Nathan W. C. Leigh, Alberto Sesana, and Rosalba Perna. "The cosmological distribution of compact object mergers from dynamical interactions with SMBH binaries." Monthly Notices of the Royal Astronomical Society 490, no. 2 (2019): 2627–47. http://dx.doi.org/10.1093/mnras/stz2780.

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ABSTRACT We combine sophisticated high-precision scattering experiments, together with results from the Millenium-II simulation, to compute the cosmic merger rate of bound compact object (CO) binaries dynamically interacting with supermassive black hole binaries (SMBHBs). We consider binaries composed of white dwarfs (WDs), neutron stars (NSs), and black holes (BHs). The overall merger rates for WD–WD, NS–NS, BH–BH, BH–NS binaries, and EBBH (eccentric binaries of BHs) from redshift ∼5 are found to be $4.32\times 10^3\, \mathrm{yr}^{-1}(5.93\times 10^2\, \mathrm{yr}^{-1}$ for Type Ia SNe), $82.
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Luo, Xuepin, Shan Fu, and Weiyan Zheng. "Newly Dignosed Early T-Cell Precursor Acute Lymphoblastic Leukemia Successfully Treated with Venetoclax Combined with DA and IA Regime." Blood 142, Supplement 1 (2023): 5888. http://dx.doi.org/10.1182/blood-2023-191324.

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Abstract Background: Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a distinctive and extremely aggressive subtype of T-ALL. It is characterized by the aberrant expression of myeloid/stem cell antigens and the lack of Tlymphoid antigens including CD1a, CD4, CD5, and CD8. Currently, standard combination chemotherapy is still the mainstay of ETP-ALL treatment. However, the optimal management remains to be determined. ETP-ALL has low response rates to conventional chemotherapy and high relapse rates with a grim prognosis. Although some ETPALL patients achieved morphologic comple
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Moreira, Jorge, Elisabete Moreira, Filomena Azevedo, and Alberto Mota. "Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2006-2012)." Acta Médica Portuguesa 27, no. 4 (2014): 480. http://dx.doi.org/10.20344/amp.5211.

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&lt;strong&gt;Introduction:&lt;/strong&gt; Malignant melanoma is the most aggressive skin cancer and its incidence has been increasing in recent decades. The cure depends on early diagnosis and understanding melanoma epidemiology is of great importance for the implementation of programs of primary prevention and early detection.&lt;br /&gt;&lt;strong&gt;Material and Methods:&lt;/strong&gt; We reviewed the clinical cases of primary cutaneous malignant melanoma diagnosed between January 2006 and December 2012 at Centro Hospitalar de São João, in Porto.&lt;br /&gt;&lt;strong&gt;Results:&lt;/stron
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Dosch, H. Michael, Roy K. Cheung, Wolfram Karges, Massimo Pietropaolo, and Dorothy J. Becker. "Persistent T Cell Anergy in Human Type 1 Diabetes." Journal of Immunology 163, no. 12 (1999): 6933–40. http://dx.doi.org/10.4049/jimmunol.163.12.6933.

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Abstract An anergic phenotype has been observed in nonobese diabetic (NOD) mice and some autoreactive T cells from patients with type I diabetes. To better understand this phenomenon, we measured T cell proliferative responses to 10 diabetes-associated and up to 9 control Ags/peptides in 148 new diabetic children, 51 age- and MHC (DQ)-matched siblings (sibs), 31 patients with longstanding diabetes, and 40 healthy controls. Most (78–91%) patient and sib responses to glutamate decarboxylase of 65 kDa (GAD65), islet cell cytoplasmic autoantibody (ICA) 69, diabetes-associated T cell epitopes in IC
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Menges, S., H. Wei, D. Faber, D. Kraemer, and C. Long. "140 UTILIZATION OF LASER-ASSISTED HATCHING TO IMPROVE THE PREGNANCY RATE OF IN VITRO-FERTILIZED BOVINE EMBRYOS." Reproduction, Fertility and Development 20, no. 1 (2008): 150. http://dx.doi.org/10.1071/rdv20n1ab140.

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In vitro-produced (IVP) bovine embryos are known to produce a lower pregnancy rate when compared to conventional in vivo-produced embryos. The inability of the IVP embryo to hatch from the zona pellucida (ZP) after embryo transfer is thought to be one contributing factor. This study was designed to evaluate the utilization of a microscope objective-mounted laser to cut the ZP to assist hatching prior to transfer into the recipient. Preliminary data were acquired to evaluate the effect of laser treatment on in vitro development and blastomere survival following treatment. In six replicates, bov
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Astuhuamán, César. "Book reviews - Richard L. Burger (ed.). The life and writings of Julio C. Tello: America's first indigenous archaeologist. x+364 pages, 148 illustrations. 2009. Iowa City (IA): University of Iowa Press; 978-1-58729-783-0 paperback $ 39.95." Antiquity 85, no. 330 (2011): 1493–94. http://dx.doi.org/10.1017/s0003598x00062311.

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Hou Yin, Tham. "Tahap kepuasan ibu bapa terhadap kualiti pendidikan prasekolah di daerah Maran, Pahang." Jurnal Pendidikan Awal Kanak-Kanak Kebangsaan 7 (December 21, 2018): 83–100. http://dx.doi.org/10.37134/jpak.vol7.8.2018.

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Kajian ini dijalankan untuk mengenal pasti tahap kepuasan ibu bapa terhadap kualiti pendidikan prasekolah di daerah Maran, Pahang. Kajian ini juga menentukan perbezaan di antara tahap kepuasan ibu bapa terhadap kualiti pendidikan prasekolah dengan berdasarkan faktor jenis prasekolah, jantina, tahap pendidikan dan pendapatan. Teori Expectancy-Disconfirmation telah digunakan sebagai teori asas kajian ini. Ia disokong oleh model Harris Interactive Poll Organization. Pendekatan kuantitatif dengan reka bentuk kajian tinjauan deskriptif digunakan dalam kajian ini. Pemilihan subjek kajian dijalankan
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Yamamoto, M., and T. Ishida. "The evaluation of peritoneal lavage tumor markers for gastric cancer." Journal of Clinical Oncology 27, no. 15_suppl (2009): e15643-e15643. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e15643.

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e15643 Background: We have found that elevation of preoperative peritoneal lavage CEA levels is associated with an earlier detection of recurrent peritoneal dissemination and a poor prognosis. Methods: We have now examined findings with the combined of peritoneal lavage CEA, CA125 and CA72–4 levels with regard to prediction of the prognosis of gastric cancer patients. Ninety-four patients who were underwent surgery with gastric cancer were intraoperatively measured for tumor markers, CEA, CA125 and CA72–4 in peritoneal lavage using a chemiluminescent enzyme immunoassay. We examined whether the
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Dowdell, Kennichi C., Lesley Pesnicak, Lilia Bi, Victoria Hoffmann, V. Koneti Rao, and Stephen E. Straus. "Hydroxychloroquine Diminishes Lymphoproliferation in the Fas Deficient MRL/lpr−/− Murine Model of Autoimmune Lymphoproliferative Syndrome (ALPS)." Blood 110, no. 11 (2007): 1385. http://dx.doi.org/10.1182/blood.v110.11.1385.1385.

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Abstract Hydroxychloroquine (HCQ) is an anti-malarial drug in clinical use for decades that is finding further use as a steroid sparing agent in the treatment of immune disorders such as chronic GVHD, lupus and rheumatoid arthritis. HCQ is a lysosomotropic agent with more recent evidence showing immunomodulatory anti-TNF activity. It is currently being explored as a cytotoxic antineoplastic/antimicrobial agent. Hence, studies were conducted to determine the efficacy of HCQ to control the lymphoproliferation associated with ALPS. ALPS is an inherited disorder of apoptosis leading to lymphoproli
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Caicedo-Basurto, Ronny Leandro, Byron Manuel Camacho-Medina, Carlos Alfredo Quinga-Villa, Alex Fabián Fonseca-Lombeida, and Steve Alexander López-Freire. "Análisis y beneficios de la educación en la era de la inteligencia artificial." Journal of Economic and Social Science Research 4, no. 4 (2024): 291–302. http://dx.doi.org/10.55813/gaea/jessr/v4/n4/148.

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El estudio aborda la transformación educativa impulsada por la inteligencia artificial (IA) y los desafíos asociados a su implementación en el contexto académico. El objetivo principal es analizar los beneficios, riesgos y consideraciones éticas en la adopción de IA en la educación, mediante una revisión bibliográfica exhaustiva de estudios recientes y reportes de organismos internacionales. La metodología empleada fue de tipo exploratoria, basada en una revisión de literatura en bases de datos académicas y fuentes relevantes sobre IA y educación. Los resultados destacan que la IA permite pers
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Gibert, Isabel, Andrea R. Bellot, and Sandra Iglesia-Martín. "Integración de ChatGPT en la formación inicial de profesorado de ELE: percepciones sobre el uso de la IA en el contexto académico." Doblele. Revista de lengua y literatura 10 (December 11, 2024): 82–100. https://doi.org/10.5565/rev/doblele.148.

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Este estudio explora la integración de ChatGPT en la formación inicial del profesorado de ELE, destacando la necesidad de incluir formación en IA en el currículo docente. Los hallazgos indican una percepción positiva de ChatGPT como herramienta educativa, con estudiantes reconociendo su utilidad para mejorar el aprendizaje y la enseñanza de idiomas. A pesar de la familiaridad limitada con la IA, la mayoría aprecia la posibilidad de integrar estas herramientas en su formación. El estudio, aplicando un enfoque metodológico mixto en un grupo selecto de estudiantes, arroja luz sobre las aplicacion
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Guegan, Jean-Philippe, Florent Peyraud, Christophe Rey, et al. "Biological determinants of immune exclusion in non-small cell lung cancer: An analysis of the precision medicine BIP study." Journal of Clinical Oncology 43, no. 16_suppl (2025): 2636. https://doi.org/10.1200/jco.2025.43.16_suppl.2636.

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2636 Background: Immune exclusion has been associated with resistance to immunotherapy in NSCLC. However, its biological determinants remain largely unknown. Instead of relying on preclinical models, high-throughput profiling of patient samples using spatial transcriptomics (ST) and multiplex immunofluorescence (m-IF) offers a powerful approach to dissect immune profiles and uncover key drivers of immune response and resistance. Methods: Tumor samples collected from NSCLC patients enrolled in the BIP precision medicine study (NCT02534649) prior to initiation of ICI therapy and divided into Dis
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Daniel-Ribeiro, Cláudio Tadeu, and Yuri Chaves Martins. "Imagens internas e reconhecimento imune e neural de imagens externas: os caminhos e contextos das redes biológicas de cognição para a definição da identidade do indivíduo." Neurociências 4, no. 3 (2008): 117–48. https://doi.org/10.5281/zenodo.14504173.

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Em 2004, um artigo publicado pelo ent&atilde;o Presidente da Sociedade Brasileira de Neuroci&ecirc;ncias&nbsp;na se&ccedil;&atilde;o Perspectivas do primeiro n&uacute;mero deste peri&oacute;dico [2] foi comentado por um de n&oacute;s [3].&nbsp;Os coment&aacute;rios, que deram origem a estimulantes discuss&otilde;es com estudantes do nosso Laborat&oacute;rio, foram expandidos e transformados em dois artigos, que optamos por publicar tamb&eacute;m&nbsp;no Neuroci&ecirc;ncias, para honrar a hist&oacute;ria de suas origens. O primeiro deles [4] foi focado em&nbsp;argumentos e evid&ecirc;ncias de q
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Rey Pereira, Carlos Alberto. "Gilles de raiz de Vicente Huidobro: el compendio de definiciones y las hipótesis arriesgadas." Verba Hispanica 4, no. 1 (1994): 137–48. http://dx.doi.org/10.4312/vh.4.1.137-148.

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Si entendemos que la obra literaria puede quedar planteada como una definición o respuesta a una pregunta, podríamos conjeturar que estas definiciones, preguntas y res­ puestas tienen que ver muy a menudo -lo que no es, por supuesto, condición necesaria, ni, por añadidura, suficiente-con el fracaso y con Ia transgresión.
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Pereira, Edgard. "Entre o minério e a pedra: a poesia de Márcio Almeida e de Carlos Ávila." Revista do Centro de Estudos Portugueses 21, no. 29 (2001): 141. http://dx.doi.org/10.17851/2359-0076.21.29.141-148.

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&lt;p&gt;Algumas reflexões sobre a poesia brasileira contemporânea, destacando a produção de dois jovens poetas, Márcio Almeida e Carlos Ávila.&lt;/p&gt; &lt;p&gt; &lt;/p&gt; &lt;p&gt;Quelques reflexions sur Ia poésie brésilienne contemporaine et sur deux poetes recentes, Márcio Almeida e Carlos Ávila.&lt;/p&gt;
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Cheng, Ying, Dingzhi Huang, Zhiyong Ma, et al. "Abstract CT553: Tislelizumab (TIS) versus docetaxel (D) in patients with previously treated advanced non-squamous (non-sq) non-small-cell lung cancer (NSCLC): Subanalysis from the RATIONALE-303 phase 3 randomized clinical study." Cancer Research 82, no. 12_Supplement (2022): CT553. http://dx.doi.org/10.1158/1538-7445.am2022-ct553.

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Abstract Background: At a predefined interim analysis (IA), RATIONALE-303 (NCT03358875) demonstrated improved overall survival (OS) for TIS vs D in the intent-to-treat (ITT), with a manageable safety profile. Disease characteristics, standard of care and treatment/prognosis differ between histologic types of NSCLC. Here, we report on the non-sq population. Methods: 805 patients with histologically confirmed, advanced NSCLC with progressive disease during or after ≥ 1 platinum (Pt)-containing chemotherapy regimen were randomized (2:1) to TIS 200 mg or D 75 mg/m2 every 3 weeks until disease prog
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Borovok, Ilya, Rachel Kreisberg-Zakarin, Michaela Yanko, et al. "Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth The GenBank/EMBL/DDBJ accession numbers for the sequences determined in this paper are AJ224870, AJ276618, AJ277778, AJ295338 and AJ295339." Microbiology 148, no. 2 (2002): 391–404. http://dx.doi.org/10.1099/00221287-148-2-391.

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Genes encoding two ribonucleotide reductases (RNRs) were identified in members of the genus Streptomyces. One gene, nrdJ, encoded an oligomeric protein comprising four identical subunits each with a molecular mass of ∼108 kDa. The activity of this protein depended on the presence of 5′-deoxyadenosylcobalamine (coenzyme B12), establishing it as a class II RNR. The Streptomyces clavuligerus nrdJ gene was cloned, using internal peptide sequences from the purified protein, and was found to encode a polypeptide of 961 aa. Molecular phylogenetic analysis showed that the S. clavuligerus class II RNR
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Khamdevi, Muhammar. "THE EFFECTS OF TOURISM ON VERNACULAR HOUSES IN TRADITIONAL VILLAGE: THE COMPARISON BETWEEN KAMPUNG NAGA IN WEST JAVA AND DESA KANEKES IN BANTEN." NALARs 15, no. 2 (2016): 141. http://dx.doi.org/10.24853/nalars.15.2.141-148.

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ABSTRACT. Tourism is one of the significant economic sectors in Indonesia. It has major, economic, social and environmental impacts. However, it may become unsustainable tourism, if its management ignores environmental issues, especially the degradation of the cultural heritage environment. Kampung Naga in West Java and Desa Kanekes in Banten are two cultural heritage villages that became tourist attractions in Indonesia. Their vernacular houses experienced several shifts and changes since then. How are the effects of tourism in Kampung Naga and Desa Kanekes on their vernacular houses? Are the
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Yumielda, Vivi Destri. "INTERAKSI SIMBOLIK DALAM LUKISAN “KAMPUNG KARO” KARYA RASINTA TARIGAN." Gorga : Jurnal Seni Rupa 12, no. 1 (2023): 148. http://dx.doi.org/10.24114/gr.v12i1.41164.

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Rasinta Tarigan is a Karo artist who created a painting titled “Kampung Karo” with the romance of Karo people’s lives. He emphasized the cultural values of the Karo people in the past into his paintings. The painting has its own place for the public of his art, as Rasinta specifically presented this work to those who shared the same socio-cultural background as the value groups in the painting. The communication that occurs between the art public – arts – creator painting, there is interaction in it and causes interpretation through symbols but there is still miscommunication or misperception
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Bhavishya, Ravi Bhat, S. Elain Apshara, et al. "Genotypic variation in flowering, fruit set, and cherelle wilt, and their relationship with leaf nutrient status in cocoa (Theobroma cacao L.) grown in humid tropics of India." Innovations in Agriculture 7 (March 16, 2024): 1–5. http://dx.doi.org/10.3897/ia.2024.124253.

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Cocoa is an important plantation crop grown for its beans, used in the chocolate and confectionary industry. It produces a large number of perfect flowers on the stem (cauliflorous), but the fruit set is low. There is a lack of comprehensive information regarding the genotypic variability in flowering, fruit set, and cherelle wilt, as well as their relationship with leaf nutrient status. Thus, a field study was undertaken at ICAR-Central Plantation Crops Research Institute, Regional Station, Vittal, to elucidate the influence of leaf nutrient status on flowering, fruit set, and cherelle wilt i
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Bhavishya, Ravi Bhat, S. Elain Apshara, et al. "Genotypic variation in flowering, fruit set, and cherelle wilt, and their relationship with leaf nutrient status in cocoa (Theobroma cacao L.) grown in humid tropics of India." Innovations in Agriculture 7 (March 16, 2024): 1–5. https://doi.org/10.3897/ia.2024.124253.

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Cocoa is an important plantation crop grown for its beans, used in the chocolate and confectionary industry. It produces a large number of perfect flowers on the stem (cauliflorous), but the fruit set is low. There is a lack of comprehensive information regarding the genotypic variability in flowering, fruit set, and cherelle wilt, as well as their relationship with leaf nutrient status. Thus, a field study was undertaken at ICAR-Central Plantation Crops Research Institute, Regional Station, Vittal, to elucidate the influence of leaf nutrient status on flowering, fruit set, and cherelle wilt i
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Zhang, Ju-Jia, Xiao-Feng Wang, Jin-Ming Bai, et al. "OPTICAL AND ULTRAVIOLET OBSERVATIONS OF THE NARROW-LINED TYPE Ia SN 2012fr IN NGC 1365." Astronomical Journal 148, no. 1 (2014): 1. http://dx.doi.org/10.1088/0004-6256/148/1/1.

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Fathorrahman, Fathorrahman. "PENGATURAN DAN IMPLIKASI PENGUJIAN FORMIL UNDANG-UNDANG DI MAHKAMAH KONSTITUSI." HUKMY : Jurnal Hukum 1, no. 2 (2021): 133–48. http://dx.doi.org/10.35316/hukmy.2021.v1i2.133-148.

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Sebagai lembaga yang memiliki fungsi khusus, Mahkamah Konstitusi memiliki kewenangan kehakiman yang berbeda dengan lembaga kehakiman lainnya. Ia memiliki atribusi khusus dan terbatas dalam menjalakan kewenangan dan fungsinya dalam sistem ketatanegaraan di Indonesia. Salah satu kewenagan yang dimiliki oleh Mahkamah Konstitusi adalah menguji validitas produk lembaga legislatif berupa Undang-Undang yang potensial bertengtangan dengan Undang-Undang Dasar Negara Republik Indonesia. Secara umum, semua produk legislasi harus memenuhi tertib norma dan tertib prosedur. Tertib norma yang dimaksud adalah
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Rodney, Steven A., Adam G. Riess, Louis-Gregory Strolger, et al. "TYPE Ia SUPERNOVA RATE MEASUREMENTS TO REDSHIFT 2.5 FROM CANDELS: SEARCHING FOR PROMPT EXPLOSIONS IN THE EARLY UNIVERSE." Astronomical Journal 148, no. 1 (2014): 13. http://dx.doi.org/10.1088/0004-6256/148/1/13.

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Kachkovska, Vladyslava, Anna Kovchun, Iryna Dudchenko, and Liudmyla Prystupa. "EFFECTIVENESS OF COMPLEX TREATMENT OF PATIENTS WITH EARLY-ONSET AND LATE-ONSET BRONCHIAL ASTHMA ASSOCIATED WITH OBESITY." Eastern Ukrainian Medical Journal 12, no. 1 (2024): 148–59. http://dx.doi.org/10.21272/eumj.2024;12(1):148-159.

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The objective of the study was a comparative assessment of the clinical effectiveness of atorvastatin and vitamin D effect on proteolytic activity in obese patients with BA depending on the age of BA onset. Materials and Methods. We examined 195 patients with BA and obesity and 95 apparently healthy individuals. The patients were divided into 2 groups with regard to the age of BA onset: Group I included 100 patients with early-onset asthma, and Group II included 95 patients with late-onset asthma. Patients with complete BA control at baseline and those having achieved BA control after backgrou
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Kamal, Ahmed Marghany, Abd El Galeel Omar Yasser, and Hussien Kamel Hosam. "Left ventricular diastolic dysfunction detected by speckle tracking in hypertensive patients with preserved ejection fraction." Biolife 5, no. 2 (2022): 238–44. https://doi.org/10.5281/zenodo.7364355.

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<strong>ABSTRACT</strong> To detect early diastolic dysfunction in the left ventricle in hypertensive patients with preserved ejection fraction using 2D speckle tracking echocardiography. This is a prospective study that was carried on (80) hypertensive patients referred to Al Azhar university hospital outpatient clinic for evaluation and treatment of hypertension and (20) age and sex matched healthy volunteers as a control group. All subjects underwent convential echocardiographic examination and Assesment of diastolic dysfunction by speckle tracking. Impairment of diastolic function detected
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Sally, S. Donia, and R. Alsharaky Dalia. "The role of melatonin on GLUT-1 expression in rat testicular tissue metabolism in metabolic syndrome." Biolife 4, no. 2 (2016): 347–56. https://doi.org/10.5281/zenodo.7318049.

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<strong>ABSTRACT</strong> Within the testis, glucose is essential for spermatogenesis. Melatonin cooperates with insulin in the regulation of glucose metabolism. Since the effects of melatonin on male reproductive system remain largely indefinite, we investigate the effects of melatonin on (GLUT-1), male hormonal level and oxidative state in testicular tissue in metabolic syndrome. Twenty-four rats had been divided randomly into three groups: control, fructose, and fructose plus melatonin. Metabolic syndrome (MS) was induced by fructose rich diet and melatonin was injected at a dose of 5 mg/kg
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Zamith Cruz, Judite. "Marina. Lucchesi, Marco. Santo André (SP): Rua do Sabão, 2023." EccoS – Revista Científica, no. 67 (December 18, 2023): e25392. http://dx.doi.org/10.5585/eccos.n67.25392.

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Jogo de espelhos e palavras Analogias duma beleza transitiva Foi entre “formigas e cupins”[1] que descobri e inventei por “ver” o que lia. Do jardim a casa, numa aprazível “distração”, li Marina (do latim, marinus, “marinho”). Se ia em busca de cupins, absorvi-me logo numa bela atividade intrínseca de “ler” a natureza humana. Os estados/processos emocionais deram-se ao meu sonho acordado, frente à lua cheia. Por contraste mínimo, o que acontece no sonho propriamente dito é antes uma não narrativa, uma dissociação não controlada, exibida a superfície de fundo inacessível[2], graciosa alternativ
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Sato, Kenta, and Shunsuke Takagi. "Deformations of Log Terminal and Semi Log Canonical Singularities." Forum of Mathematics, Sigma 11 (2023). http://dx.doi.org/10.1017/fms.2023.28.

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Abstract In this paper, we prove that klt singularities are invariant under deformations if the generic fiber is $\mathbb {Q}$ -Gorenstein. We also obtain a similar result for slc singularities. These are generalizations of results of Esnault-Viehweg [Math. Ann.271 (1985), 439–449] and S. Ishii [Math. Ann.275 (1986), 139–148; Singularities (Iowa City, IA, 1986) Contemporary Mathematics, vol. 90 (American Mathematical Society, Providence, RI, 1989), 135–145].
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Liu, Xiang, Suzanne Bennett Johnson, Kristian F. Lynch, et al. "Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5–15-Year-Old Children Followed in the TEDDY Study." Diabetes Care, May 4, 2023. http://dx.doi.org/10.2337/dc23-0036.

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OBJECTIVE This study investigated physical activity and its association with the development of islet autoimmunity and type 1 diabetes in genetically at-risk children aged 5–15 years. RESEARCH DESIGN AND METHODS As part of the longitudinal Environmental Determinants of Diabetes in the Young (TEDDY) study, annual assessment of activity using accelerometry was conducted from age 5 years. Time-to-event analyses using Cox proportional hazard models were used to assess the association between time spent in moderate to vigorous physical activity per day and the appearance of one or several autoantib
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Alcantara da Silva, João Vitor, Jessica Ispada, Ricardo Perecin Nociti, et al. "The central role of pyruvate metabolism on the epigenetic maturation and transcriptional profile of bovine oocytes." Reproduction, January 2024. http://dx.doi.org/10.1530/rep-23-0181.

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Pyruvate, the final product of glycolysis, undergoes conversion into acetyl-CoA within the mitochondria of oocytes, serving as a primary fuel source for the tricarboxylic acid (TCA) cycle. The citrate generated in the TCA cycle can be transported to the cytoplasm and converted back into acetyl-CoA. This acetyl-CoA can either fuel lipid synthesis or act as a substrate for histone acetylation. This study aimed to investigate how pyruvate metabolism influences lysine 9 histone 3 acetylation (H3K9ac) dynamics and RNA transcription in bovine oocytes during in vitro maturation (IVM). Bovine cumulus-
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"Pemikiran Fiqh Imam Ja’far Asshiddiq." Siyasah Wa Qanuniyah 1, no. 1 (2023): 1–13. http://dx.doi.org/10.61842/swq/v1i1.4.

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Penelitian ini mengangkat tentang pemikiran fiqh Imam Ja’far Asshiddiq (melacak perkembangan mazhab ja’fariyah). Dalam penelitian ini, penulis menggunakan penelitian kepustakaan (library research), dan pengumpulan data dilakukan dengan mengkaji buku dan kitab tentang Fiqh Ja’fari, ushul fiqh Ja’fariyah dijadikan sebagai bahan primer, dan buku-buku yang lainnya yang berhubungan dengan pembahasan penelitian ini sebagai bahan sekunder, sehingga pola ini berbentuk kualitatif. Di samping itu, analisa yang penulis gunakan adalah analisis deskriptif. Dari hasil penelitian ini ditemukan kesimpulan bah
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Herniati, M. Husni Ingratubun, and Kusnanto. "TANGGUNG JAWAB PERAWAT YANG MELAKUKAN TINDAK MEDIK DALAM RANGKA MELAKSANAKAN TUGAS DOKTER DI RUAH SAKIT UMUM DAERAH JAYAPURA." Jurnal Ius Publicum 2, no. 2 (2021). http://dx.doi.org/10.55551/jip.v2i2.13.

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Penelitian ini dengan judul Tanggung Jawab Perawat yang Melakukan Tindak MedikDalam Rangka Melaksanakan Tugas Dokter di RSU Daerah Jayapura, dengan menggunakan metode penelitian penelitian hukum normatif-empiris (applied law research) adalah penelitian yangmenggunakan studi kasus hukum normatif-empiris dengan mengkaji berupa produk hukum yakniUndang-Undang Dasar Negara Republik Indonesia Tahun 1945. Undang-Undang Nomor 38 Tahun2014 tentang Keperawatan, Undang-Undang Nomor 36 Tahun 2009 tentang Kesehatan, UndangUndangNomor44Tahun2009tentangRumahSakit,Undang-UndangNomor29Tahun2004tentang&#x0D; P
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Tew Abdullah, Muhammad Hakimi, Norwati Roslim, Zakri Abdullah, Muhammad Nabihan Abu Bakar, and Zainal Abidin Razak. "TEKNOSTRES DALAM KALANGAN WARGA PENDIDIK DI INSTITUT PENDIDIKAN GURU KAMPUS RAJA MELEWAR KETIKA PANDEMIK COVID-19." e-Bangi Journal of Social Science and Humanities 20, no. 2 (2023). http://dx.doi.org/10.17576/ebangi.2023.2002.12.

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Teknostres merupakan satu jenis penyakit adaptasi moden yang disebabkan oleh ketidakupayaan seseorang individu untuk menampung keperluan teknologi komunikasi terkini secara sihat dan betul. Ia adalah satu gejala yang boleh dialami oleh mereka yang terdedah kepada teknologi pada suatu jangka masa tertentu. Soal-selidik telah diedarkan kepada warga pendidik secara dalam talian pada tahun 2021 (n=148) untuk mengenalpasti faktor pencetus kepada berlakunya teknostres dan tahap teknostres dalam kalangan warga pendidik di Institut Pendidikan Guru Kampus Raja Melewar (IPGKRM) ketika pandemik COVID-19.
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Hussain, Basharat, Muhammad Tahir Khalily, Ahmed Waqas, et al. "Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial." Frontiers in Psychiatry 15 (January 30, 2025). https://doi.org/10.3389/fpsyt.2024.1413809.

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BackgroundIn Pakistan, the mental health care for persons living with disabilities is insufficient, lacking a holistic approach to address their needs. This research evaluates the adapted PM+’s (IA-PM+) initial efficacy and acceptability in improving mental health among persons living with disabilities, contributing to the integration of mental health services within primary care settings in Pakistan.MethodsThis study employed a two-arm, single-blind cluster randomized controlled trial in a community setting within Union Council Kuri Dolal, Tehsil Gujjar Khan, District Rawalpindi-Pakistan. It
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Wen, Qinshu, Guangyan Wu, Ye Ji, et al. "Physician-Modified Endografts for the Treatment of Thoracic Aortic Pathologies Involving the Aortic Arch." Journal of Endovascular Therapy, October 30, 2023. http://dx.doi.org/10.1177/15266028231207023.

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Objective: This study aimed to evaluate the outcomes of physician-modified endografts (PMEGs) for the treatment of thoracic aortic pathologies involving the aortic arch. Methods: A retrospective single-center study was performed on consecutive patients with thoracic aortic pathologies treated by PMEGs between February 2018 and May 2022. Data on baseline characteristics, operative procedure, and follow-up information were collected. The endpoints included technical success, complications, mortality, overall survival, re-intervention, and target vessel instability. Results: This study comprised
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