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1

Sasajima, Hirofumi, Masahiro Zako, Yoshiki Ueta, et al. "Direct Photocoagulation for Treating Microaneurysms with Hyperreflective Ring in Eyes with Refractory Macular Edema Associated with Branch Retinal Vein Occlusion." Journal of Clinical Medicine 11, no. 3 (2022): 823. http://dx.doi.org/10.3390/jcm11030823.

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Microaneurysms (MAs) with hyperreflective rings are sometimes detected in eyes with refractory macular edema (ME) associated with branch retinal vein occlusion (BRVO) for more than 12 months after onset when examined using optical coherence tomography (OCT). We proposed that these MAs could result in refractory ME secondary to BRVO and hypothesized that OCT-guided direct photocoagulation of MAs could result in a reduction in refractory ME. Eleven eyes (from eleven different patients) with refractory ME associated with BRVO for more than 12 months following initial treatment were included. The
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MOUSAVI, AMIRABBAS, GHOLAMREZA ABEDI, ALIREZA JAHANDIDEH, and SAEED HESARAKI. "Comparative study of midazolam-propofol and metamizole-propofol clinical effects in domestic pigeons." Medycyna Weterynaryjna 74, no. 1 (2018): 6012–2018. http://dx.doi.org/10.21521/mw.6012.

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This study was conducted to determine the quality of anesthesia by evaluating the clinical effects of midazolam-propofol and metamizole-propofol on domestic pigeons. The aim of the study was to choose an appropriate injectable anesthetic protocol by utilizing midazolam and metamizole as pre-anesthetic drugs in order to reduce the dose of propofol and decrease side effects. Eighteen male pigeons weighing 304.2±32.3g (mean±SD) were randomly allocated to three groups of six pigeons each. Midazolam (6 mg/kg/IM) and metamizole (500 mg/kg/IM) were used five minutes prior to administration of propofo
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Egger, Thomas, and Joelle Leonie Flueck. "Energy Availability in Male and Female Elite Wheelchair Athletes over Seven Consecutive Training Days." Nutrients 12, no. 11 (2020): 3262. http://dx.doi.org/10.3390/nu12113262.

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Background: Low energy availability (LEA) is a major problem as athletes often restrict their energy intake. It has been shown that LEA occurs often in female and endurance athletes and in athletes from weight-sensitive or aesthetic sports. The purpose of this study was to investigate energy availability (EA) in elite wheelchair athletes. Methods: Fourteen elite wheelchair athletes (8 males; 6 females) participated. Data were collected using a weighed seven-day food and training diary to estimate energy intake and exercise energy expenditure. Resting energy expenditure and body composition wer
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Dominguez, José Henrique, Matheus Gomes Lopes, Fabrício Amadori Machado, et al. "Body Temperature and Reproductive Performance of Beef Heifers Supplemented With Rumen-Protected Methionine." Journal of Agricultural Studies 8, no. 3 (2020): 601. http://dx.doi.org/10.5296/jas.v8i3.16793.

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This study aimed to assess the reproductive performance and body temperature of beef heifers supplemented with rumen-protected methionine (RPM) in an extensive grazing system and mated during the summer. One hundred 5/8 Angus 3/8 Brahman heifers were homogeneously divided into the control group (n=48, CG) supplemented with mineral salt ad libitum and methionine group (n=52, MG) who received the same supplementation plus 4 g of methionine per 100 g of mineral salt. The groups were fixed-time artificial inseminated (FTAI) 45 days after starting the supplementation. On day 0 of the FTAI protocol,
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Luo, Du-Qiang, Hong-Jun Shao, Hua-Jie Zhu, and Ji-Kai Liu. "Activity in vitro and in vivo against Plant Pathogenic Fungi of Grifolin Isolated from the Basidiomycete Albatrellus dispansus." Zeitschrift für Naturforschung C 60, no. 1-2 (2005): 50–56. http://dx.doi.org/10.1515/znc-2005-1-210.

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In the course of screening for novel naturally occurring fungicides from mushrooms in Yunnan province, China, the ethanol extract of the fruiting bodies of Albatrellus dispansus was found to show antifungal activity against plant pathogenic fungi. The active compound was isolated from the fruiting bodies of A. dispansus by bioassay-guided fractionation of the extract and identified as grifolin by IR, 1H and 13C NMR and mass spectral analysis. Its antifungal activities were evaluated in vitro against 9 plant pathogenic fungi and in vivo against the plant disease of Erysiphe graminis. In vitro,
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Singer, Titi, Hae-Young Kim, Nancy F. Olivieri, et al. "Hemoglobin H-Constant Spring in North America: A Common Alpha Thalassemia with Frequent Complications." Blood 112, no. 11 (2008): 1880. http://dx.doi.org/10.1182/blood.v112.11.1880.1880.

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Abstract The α-globin Constant Spring (CS) mutation (α142 STOP → Gln; TAA → CAA) is the most prevalent non-deletional thalassemia in south East Asia and southern China. DNA diagnosis of Hb H Constant Spring (Hb H CS; 2 α-gene deletions and 1 CS mutation) is often required because it can be missed by electrophoresis. The clinical phenotype of Hb H CS is more severe than classical Hb H disease. We sought to characterize the unique hematological and clinical features of Hb H CS patients, especially compared to those with Hb H disease, who were identified through the Thalassemia Clinical Research
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Beykaya, Mehmet, Zeliha Yıldırım, Ayşe Özbey, and Metin Yıldırım. "Sivas İlindeki Bazı Süt İşletmelerine Gelen Sütlerin Ağır Metal İçeriklerinin Belirlenmesi." Turkish Journal of Agriculture - Food Science and Technology 7, no. 1 (2019): 105. http://dx.doi.org/10.24925/turjaf.v7i1.105-109.2164.

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In this study, some heavy metal contents, including cadmium (Cd), copper (Cu), chrome (Cr) and lead (Pb) of 50 raw bulk milk samples obtained from 5 different dairy plants in the Sivas and its vicinity were investigated. The contamination level of Cd, Cu and Cr were found 8.896, 33.69 and 31.81 µg/kg respectively in milk samples. Lead contents of 92% of the milk samples were below the detection limit, but 8% of the samples contained 304.1 - 503.4 µg/kg lead.
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Guo, Runjiang, Yurui Xing, Mengqian Liu, Tanglong Bai, Chaodan Pu, and Hongti Zhang. "Facile Synthesis of BiVO4@ZIF−8 Composite with Heterojunction Structure for Photocatalytic Wastewater Treatment." Materials 14, no. 23 (2021): 7424. http://dx.doi.org/10.3390/ma14237424.

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Water pollution has always been a serious problem across the world; therefore, facile pollutant degradation via light irradiation has been an attractive issue in the field of environmental protection. In this study, a type of Zn-based metal–organic framework (ZIF−8)-wrapped BiVO4 nanorod (BiVO4@ZIF−8) with high efficiency for photocatalytic wastewater treatment was synthesized through a two-step hydrothermal method. The heterojunction structure of BiVO4@ZIF−8 was confirmed by morphology characterization. Due to the introduction of mesoporous ZIF−8, the specific surface area reached up to 304.5
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Hsu, Leh-Yeh, Jeff W. Kampf, and Christer E. Nordman. "Structure and pseudosymmetry of cholesterol at 310 K." Acta Crystallographica Section B Structural Science 58, no. 2 (2002): 260–64. http://dx.doi.org/10.1107/s0108768101018729.

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The structure of cholesterol above the (304.8 K) phase transition, previously published in preliminary form [Hsu & Nordman (1983). Science, 220, 604–606], has been fully refined using augmented X-ray data. The crystals are triclinic, space group P1, with (reassigned) cell parameters a = 27.565 (10), b = 38.624 (16), c = 10.748 (4) Å, α = 93.49 (3), β = 90.90 (3), γ = 117.15 (3)°, and V = 10151 (7) Å3. The unit cell contains Z = 16 molecules, of which eight are related to the other eight by unusual twofold rotational pseudosymmetry. The structure is related to the room-temperature phase, wi
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Talakua, Willem, and Eygner Gerald Talakua. "MAKSIMASI KEUNTUNGAN USAHA PUKAT CINCIN DI NEGERI LATUHALAT PADA MUSIM TIMUR." PAPALELE (Jurnal Penelitian Sosial Ekonomi Perikanan dan Kelautan) 2, no. 1 (2018): 22–32. http://dx.doi.org/10.30598/papalele.2018.2.1.22.

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The purpose of this study is to study the maximization of business profits through the determination of the optimal use of production factors in the trawl ring business in Latuhalat. Observations and direct interviews based on questionnaires were carried out on 3 fishermen who owned trawl ring businesses in 3 hamlets in Latuhalat. Data were analyzed using business profit analysis methods and linear programming analysis. The results showed that: 1). The optimal use of production factors for trawling by the respondents in Latuhalat is 41 - 45 trips in June using 15.2 - 21.1 liters of gasoline, 2
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Brylak, Markus, and Wolfgang Jeitschko. "Ternary Antimonides LnTSb3 with Ln = La-Nd, Sm and T = V, Cr." Zeitschrift für Naturforschung B 50, no. 6 (1995): 899–904. http://dx.doi.org/10.1515/znb-1995-0611.

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The title compounds were prepared by reaction of the elemental components. They crystallize in a new structure type, which was determined from single-crystal X -ray data of CeCrSb3: Pbcm, a = 1310.8(3), b = 618.4(1), c = 607.9(1) pm, Z = 4, R = 0.029 for 648 structure factors and 32 variable parameters. The structure of the antimonide CeVSb3 is isotypic: a = 1319.0(2), b = 623.92(8), c = 603.03(8) pm , R = 0.041 for 477 structure factors and 32 variables. The transition metal site and one of the three antimony sites were found to have partial occupancies resulting in the exact compositions CeV
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Hevko, Ivan, Roman Rohatynsky, Oleg Lyashuk, Mikhajlo Levkovich, and Volodymyr Teslia. "Structural Synthesis of Brake Systems With Technical and Economic Rationale." Central Ukrainian Scientific Bulletin. Technical Sciences 2, no. 5(36) (2022): 186–94. http://dx.doi.org/10.32515/2664-262x.2022.5(36).2.186-194.

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As a result of the synthesis of truck semi-trailer bodies by morphological analysis using hierarchical grouping and advanced engineering solutions for creating structures with improved technical and economic characteristics by analyzing the influence of various factors on design features. The data of the research are based on the stress - strain state (VAT) of the Simulation engineering analysis of the specialized software complex SolidWorks on the CAD model of the body of the truck semi - trailer. synthesis, brake disc, friction material. The synthesis of truck semi-trailer bodies was carried
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13

Ren, Ziming, Li Yang, Qingyun Ma, et al. "Meroterpenoids and Steroids from the Marine-Derived Fungus Trametes sp. ZYX-Z-16." Molecules 27, no. 24 (2022): 8782. http://dx.doi.org/10.3390/molecules27248782.

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Marine fungi can metabolize structurally diverse active components, and have become an important source of drug lead molecules. In the present study, the chemical investigation on the EtOAc extract of the fermentation broth of the marine-derived fungus Trametes sp. ZYX-Z-16 led to the isolation of eight meroterpenoids (1–8), including two undescribed ones, together with ten ergostane steroid analogues (9–18). The structures of two new spiromeroterpenoids, asnovolin H (1) and asnovolin I (2), were determined based on 1D, 2D NMR, and HRESIMS spectroscopic data along with ECD spectra calculations
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14

Jann, Michael W., Troy L. ZumBrunnen, Srini N. Tenjarla, Earl S. Ward, and Donald J. Weidler. "Relative Bioavailability of Ondansetron 8‐mg Oral Tablets versus Two Extemporaneous 16‐mg Suppositories: Formulation and Gender Differences." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 18, no. 2 (1998): 288–94. http://dx.doi.org/10.1002/j.1875-9114.1998.tb03855.x.

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Study Objective. To compare the relative bioavailability of two 16‐mg extemporaneously prepared suppository formulations with that of an 8‐mg commercially available oral tablet.Design. Prospective, crossover bioavailability study.Setting. Inpatient clinical research center.Subjects. Sixteen young, nonsmoking, healthy volunteers.Interventions. Blood samples were obtained 24 and 48 hours after administration of an 8‐mg oral ondansetron tablet and 16‐mg suppository, respectively. Two 16‐mg suppository formulations were compounded using commercially available Fattibase and Polybase.Measurements an
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Zhang, Jiaqi, Xinli Lu, Wei Zhang, et al. "Simulations of Heat Supply Performance of a Deep Borehole Heat Exchanger under Different Scheduled Operation Conditions." Processes 10, no. 1 (2022): 121. http://dx.doi.org/10.3390/pr10010121.

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With the changing world energy structure, the development of renewable energy sources is gradually accelerating. Among them, close attention has been given to geothermal energy because of its abundant resources and supply stability. In this article, a deep borehole heat exchanger (DBHE) is coupled with a heat pump system to calculate the heat supply and daily electricity consumption of the system. To make better use of the peaks and valleys in electricity prices, the following three daily operating modes were studied: 24-h operation (Mode 1), 8-h operation plus 16-h non-operation (Mode 2), and
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Luedeman, J., and K. R. Ostlie. "Control of First Generation European Corn Borer, 1992." Insecticide and Acaricide Tests 18, no. 1 (1993): 205. http://dx.doi.org/10.1093/iat/18.1.205.

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Abstract Performance of aerially applied permethrin against ECB was evaluated using 2 different volumes of water carrier. The site was a 135.9 ha commercial corn field located north of Sauk Centre, Stearns county, MN, planted on 5 May, at a population of 71,662 plants/ha. The plots, which measured 15.2 m by 304.8 m (0.91 m row spacing), were established on 12 Jul. Treatments included permethrin @ 0.17 kg(AI)/ha aerially applied with 18.7 liter/ha water and 28.01 liter/ha water and an untreated check. Treatments were arranged in a randomized complete block with 4 replications. Insecticides were
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17

Linhoss, John E., Joseph L. Purswell, and Jeremiah D. Davis. "Radiant Flux Preference of Neonatal Broiler Chicks During Brooding." Transactions of the ASABE 61, no. 4 (2018): 1417–23. http://dx.doi.org/10.13031/trans.12775.

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Abstract. Radiant heat is the most common method of providing supplemental heat in a broiler house. However, little information exists about chick preference for radiant flux. Identifying the ranges of radiant flux that chicks prefer would allow improved management of the thermal environment. The objectives of this study were to determine the radiant flux ranges preferred by broiler chicks during the first eight days of brooding. Three trials were conducted using straight-run broiler chicks. A total of 88 chicks were randomly allocated into two mixed-gender groups and placed into identical 1 m
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Mancera-Rodríguez, Néstor Javier. "Biología reproductiva de Brycon henni (Teleostei: Bryconidae) y estrategias de conservación para los ríos Nare y Guatapé, cuenca del río Magdalena, Colombia." Revista de Biología Tropical 65, no. 3 (2017): 1105. http://dx.doi.org/10.15517/rbt.v65i3.29453.

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Fish can modify features of their life histories through evolutionary mechanisms to ensure the maintenance of their populations in response to environmental changes and/or fishing pressure. The reproductive biology of characid fish B. henni, in the Nare and Guatapé Rivers, Magdalena River Basin, Colombia was studied, and suggestions for conservation are presented. Ten field samplings were carried out between October 2007 and February 2012, in periods of rain, dry, transition from rain to dry and transition from dry to rain. A total of 848 specimens were collected, 360 of which were females, 44
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Anggita, Sheilla Rully, and Heri Susanto. "Preparation and Microstructure of Ag Doped on ZnO." Journal Of Natural Sciences And Mathematics Research 2, no. 2 (2017): 148. http://dx.doi.org/10.21580/jnsmr.2016.1.2.1657.

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<div style="text-align: justify;"><div>Various concentration of silver (Ag) dopant on ZnO (ZnO:Ag) 2-8 mol% with solgel method were deposited on glass substrates that has been heated to a temperature of 250°C for 1h using a thermal spray coating technique and then annealed on 400C for 1h. The obtained samples were characterized by Scanning Electron Microscopy (SEM). The effect of various Ag dopant on ZnO on the microstructure are investigated. The results showed that the microstructure of ZnO:Ag are the surface of ZnO make ganglia phase with Ag grains covered the surface. The addi
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Konečný, Roman, Zuzana Křížová, Jan Hladký, et al. "Iodine content development in raw cow’s milk in three regions of the Czech Republic between the years 2008 and 2018." Acta Veterinaria Brno 88, no. 3 (2019): 265–70. http://dx.doi.org/10.2754/avb201988030265.

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The study examines an analysis and evaluation of iodine content in raw cow’s milk in three regions of the Czech Republic between the years 2008 and 2018. Bulk milk samples were collected at dairy farms situated in South Bohemia, Central Bohemia, and the Vysočina Region. Iodine in milk was determined on the basis of alkaline ashing, using the spectrophotometric method according to Sandell-Kolthoff. The highest mean iodine content was measured in 2009 (485.5 ± 408.2 μg/l) and the lowest in 2016 (169.2 ± 71.7 μg/l). Since 2010 there has been a gradual decline of iodine concentration, from 479.5 ±
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Burapan, Supawadee, Mihyang Kim, Yingyong Paisooksantivatana, Bekir Engin Eser, and Jaehong Han. "Thai Curcuma Species: Antioxidant and Bioactive Compounds." Foods 9, no. 9 (2020): 1219. http://dx.doi.org/10.3390/foods9091219.

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For the functional food applications, antioxidant properties and the bioactive compounds of the 23 Curcuma species commercially cultivated in Thailand were studied. Total phenolic content and DPPH radical scavenging activity were determined. The concentrations of eight bioactive compounds, including curcumin (1), demethoxycurcumin (2), bisdemethoxycurcumin (3), 1,7-diphenyl-(4E,6E)-4,6-heptadien-3-ol (4), germacrone (5), furanodienone (6), zederone (7), and ar-turmerone (8), were determined from the Curcuma by HPLC. While the total phenolic content of C. longa was highest (22.3 ± 2.4 mg GAE/g,
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Puspitarani, Gavrila Amadea, Ngakan Made Rai Widjaja, and Hardany Primarizky. "Effect of L-Arginine on the Thickness Iliac Arteries Wall Post Fogarty Balloon Embolectomy Catheter in Rabbit (Oryctolagus cuniculus)." KnE Life Sciences 3, no. 6 (2017): 212. http://dx.doi.org/10.18502/kls.v3i6.1130.

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The effect of the chronic administration of L-arginine on iliac arteries thickness after surgical embolectomy using Fogarty balloon catheter were examined. Sixteen New Zealand White male rabbits underwent unilateral iliac artery surgical embolectomy using Fogarty balloon catheter. Then the animals were divided into two group of control (P0) fed with standard rabbit diet and treatment (P1) standard rabbit diet added with L-arginine in their drinking water 4 for weeks. The iliac arteries were harvested for histological slide preparation with routine method, observed under the microscope attached
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Schröter-Schmid, Ingrid, and Joachim Strähle. "Synthese und Struktur von Thiolatokomplexen des einwertigen Kupfers: Tetrameres und Octameres [CuSC6H2(i-Pr)3] / Synthesis and Structure of Thiolato Complexes of Monovalent Copper: Tetrameric and Octameric [CuSC6H2(i-Pr)3]." Zeitschrift für Naturforschung B 45, no. 11 (1990): 1537–42. http://dx.doi.org/10.1515/znb-1990-1113.

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[CuSC6H2(i-Pr)3]n = 4 (1), and n = 8 (2) are obtained from CuCO3 · Cu(OH)2 and 2,4,6-tri(isopropyl)thiophenol in a slow reaction, where long reaction times promote the formation of octameric 2.1 crystallizes as colorless platelets, space group C 2/c: a = 3647(2), b = 854.8(6), c = 2061.3(7) pm, β = 105.98(4)°, Ζ = 4. Central unit of the tetrameric complex with the symmetry C2 is a non planar eight-membered Cu–S heterocycle. The four Cu atoms form a rhombus with short edges of 269.7 and 270.1 pm. The bridging SR-ligands are arranged alternatingly above and below the Cu4 rhombus. Octameric 2 cry
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Selemani, Siwajali, Richard Madege, and Yasinta Nzogela. "Influence of storage conditions on viability and vigour of Sunflower (Helianthus annuus L.) seeds." Journal of Current Opinion in Crop Science 4, no. 3 (2023): 141–53. http://dx.doi.org/10.62773/jcocs.v4i3.211.

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The storage experiment examined the effects of storage temperatures, seed moisture contents (SMC), and storage durations (SD) on the viability and vigour of sunflower seeds. Certified sunflower seeds were evaluated for seed germination, seedling vigour, and fungal infection. A 3x3x6 factorial experiment in Completely Randomized Design was set out in four replicates. The three factors were temperature (5, 20, 35 ºC), SMC (6,8,10%), and SD (15, 30, 45, 60, 75, 90Days After Storage, DAS). Before storage (0 DAS), the initial germination percentage (GP=94%), Germination index (GI=322), Seedling vig
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Peres, L. C., D. Pincinato, L. Cutaia, R. Tribulo, and G. A. Bo. "214 EFFECT OF TIMING OF PGF, eCG, AND ESTRADIOL BENZOATE IN RECIPIENTS SYNCHRONIZED WITH A PROGESTIN-BASED PROTOCOL FOR FIXED-TIME EMBRYO TRANSFER." Reproduction, Fertility and Development 19, no. 1 (2007): 224. http://dx.doi.org/10.1071/rdv19n1ab214.

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An experiment was designed to evaluate alternative treatment protocols for fixed-time embryo transfer (FTET) in recipients in order to reduce cattle handling. Non-lactating, cycling Bos taurus � Bos indicus beef cows (n = 918), with a body condition score (BCS) of 2.5 to 3.5 out of 5, received a progesterone-releasing device (DIB; Syntex, Buenos Aires, Argentina) and 2 mg estradiol benzoate (EB; Syntex) IM on random days of the cycle (Day 0); DIB were removed on Day 8. Cows were placed randomly into 6 treatment groups in a 3 � 2 factorial design. The factors evaluated were time of administrati
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Schmidt, Jana, Clemens Hübler, Sandra Krohn, et al. "Detection of Inflammatory and Homeostasis Biomarkers after Selective Removal of Carious Dentin—An In Vivo Feasibility Study." Journal of Clinical Medicine 10, no. 5 (2021): 1003. http://dx.doi.org/10.3390/jcm10051003.

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Deep carious dentin lesions induce an immune reaction within the pulp-dentin complex, leading to the release of cytokines, which might be suitable biomarkers in pulp diagnostics. This in vivo feasibility study determines the concentration of different cytokines after selective removal of carious infected dentin (SCR). In our methodology, paired samples are obtained from 21 patients—each of them with two deep carious lesions at posterior teeth without clinical symptoms. After SCR, lesions are randomly assigned to treatment strategy: Group 1 (11 patients): Carious dentin is covered either with B
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Kluge, M., P. Schüssler, M. Dresler, et al. "FC10-02 - Ghrelin affects sleep, secretion of cortisol and growth hormone and psychopathology in patients with major depression." European Psychiatry 26, S2 (2011): 1865. http://dx.doi.org/10.1016/s0924-9338(11)73569-6.

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IntroductionGhrelin showed antidepressant-like effects in mice. Furthermore, ghrelin influences sleep and the activity of hypothalamic-pituitary-adrenal (HPA) and somatotropic axis in healthy humans as indicated by increased cortisol and growth hormone (GH) plasma levels. Both sleep and the activity of these endocrine axes are disturbed in depression.ObjectiveTo study the effect of ghrelin on psychopathology, sleep and secretion of cortisol and GH in patients with major depression.MethodsDepressive symptoms as assessed by a validated self rating scale (’Befindlichkeits-Skala’, [well-being scal
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Alqahtani, Mashael D., Nourhan Nasser, May N. Bin Jumah та ін. "Synthesis and Characterization of β-Cyclodextrin-Hybridized Exfoliated Kaolinite Single Nanosheets as Potential Carriers of Oxaliplatin with Enhanced Loading, Release, and Cytotoxic Properties". Materials 16, № 14 (2023): 4958. http://dx.doi.org/10.3390/ma16144958.

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Natural kaolinite was subjected to a successful exfoliation process into separated kaolinite nanosheets (KNs), followed by hybridization with β-cyclodextrin biopolymer (β-CD), forming an advanced bio-nanocomposite (β-CD/KNs). The synthetic products were evaluated as enhanced delivery structures for oxaliplatin chemotherapy (OXAPN). The hybridization of KNs with β-CD polymer notably enhanced the loading capacity to 355.3 mg/g (β-CD/KNs) as compared to 304.9 mg/g for KNs. The loading of OXAPN into both KNs and β-CD/KNs displayed traditional pseudo-first-order kinetics (R2 > 0.85) and a conven
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Mora, José M., and Franklin E. Castañeda. "Terrestrial movements, activity patterns and habitat use by Kinosternon scorpioides (Testudines: Kinosternidae) in Palo Verde National Park, Costa Rica." Phyllomedusa: Journal of Herpetology 21, no. 1 (2022): 3–15. http://dx.doi.org/10.11606/issn.2316-9079.v21i1p3-15.

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The Scorpion Mud turtle, Kinosternon scorpioides, is a widely distributed, semiaquatic species known to engage in regular terrestrial movement and terrestrial estivation. We studied terrestrial behavior in this species in Palo Verde National Park, northwestern Costa Rica. We determined terrestrial activity patterns by searching for active individuals during transects along 3.4 km of trails. We determined the distance that turtles traveled between the wetlands and estivation sites by fitting 10 terrestrially active individuals with a thread-bobbin tracking device attached to the rear of the car
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Kubale, John, Guillermina Kuan, Lionel Gresh, et al. "Assessing the Incidence of Symptomatic Respiratory Syncytial Virus Illness Within a Prospective Birth Cohort in Managua, Nicaragua." Clinical Infectious Diseases 70, no. 10 (2019): 2029–35. http://dx.doi.org/10.1093/cid/ciz585.

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Abstract Background Respiratory syncytial virus (RSV) causes substantial morbidity and mortality among children worldwide, commonly through acute lower respiratory tract infections (ALRI). To assess the incidence rate of symptomatic RSV illness among young children, we conducted a prospective birth cohort study following children from 0–2 years of age in Managua, Nicaragua. Methods Children meeting the testing criteria (fever, history of fever, or severe respiratory symptoms [apnea, stridor, nasal flaring, wheezing, chest indrawing, and/or central cyanosis]) were tested for RSV infections usin
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Alqahtani, Mashael Daghash, Nourhan Nasser, May N. Bin Jumah, et al. "Insight into the Morphological Properties of Nano-Kaolinite (Nanoscrolls and Nanosheets) on Its Qualification as Delivery Structure of Oxaliplatin: Loading, Release, and Kinetic Studies." Molecules 28, no. 13 (2023): 5158. http://dx.doi.org/10.3390/molecules28135158.

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Natural kaolinite underwent advanced morphological-modification processes that involved exfoliation of its layers into separated single nanosheets (KNs) and scrolled nanoparticles as nanotubes (KNTs). Synthetic nanostructures have been characterized as advanced and effective oxaliplatin-medication (OXAP) delivery systems. The morphological-transformation processes resulted in a remarkable enhancement in the loading capacity to 304.9 mg/g (KNs) and 473 mg/g (KNTs) instead of 29.6 mg/g for raw kaolinite. The loading reactions that occurred by KNs and KNTs displayed classic pseudo-first-order kin
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Kastrati, K., H. Rajab, A. Rader, et al. "AB0718 Immune-apheresis in patients with inflammatory myopathies, a case series." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1486–87. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4108.

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BackgroundIdiopathic inflammatory myopathies (IIM) comprise a heterogenous group of autoimmune diseases characterised by inflammation of muscle and affection of other organs, such as lung or skin. Some cases of IIM non-responsive to conventional treatment with glucocorticoids and DMARDs require treatment escalation. There are only limited data on efficacy and safety of immune-apheresis (IA) in IIM patients.ObjectivesThis retrospective cohort study aims to determine whether IA is effective in treating therapy-refractory IIM.MethodsPatients with active IIM undergoing IA (either plasma-exchange o
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Gummerson, Scott, Megan Smith, and Otis Warren. "Effect of an Emergency Department Closure on Homeless Patients and Adjacent Hospitals." Western Journal of Emergency Medicine 23, no. 3 (2022): 368–74. http://dx.doi.org/10.5811/westjem.2021.12.53918.

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Introduction: Homeless and housed patients differ on several emergency department (ED) metrics (emergency medical services [EMS] use, chief complaints, admission rates, etc.). On January 1, 2018, Memorial Hospital (MH), a safety-net hospital in Pawtucket, Rhode Island, closed. We studied the impact of this closure by analyzing homeless patient utilization of the two closest EDs before and after MH closed. Methods: A retrospective chart review compared the ED records of The Miriam Hospital (TMH), (1.8 miles from MH) and Rhode Island Hospital (RIH), (4.3 miles from MH). We analyzed visits betwee
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Tosta, R., R. Sala, D. Pereira, et al. "109 Effect of ruminal infusion with propylene glycol on the invitro embryo production of Holstein (Bos taurus) prepubertal heifers and pregnancy rate of the embryo transfer." Reproduction, Fertility and Development 32, no. 2 (2020): 181. http://dx.doi.org/10.1071/rdv32n2ab109.

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The aim of this study was to evaluate the effect of ruminal infusion with propylene glycol (PG) on the invitro embryo production (IVEP) of Holstein (Bos taurus) prepubertal heifers (7 to 8 months). For this study, 16 prepubertal heifers were distributed into two groups: Propylene Glycol Group (PGG; n=8) and Control Group (CG; n=7). Additionally, 8 pubertal heifers were used for the positive control group (PUB). All animals (n=23) underwent an ovum pickup (OPU) for follicular ablation on Day 0, followed by an FSH protocol treatment (160mg performed in 4 injections twice a day in decreasing dose
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Gulle, S., A. Çelik, B. Lebe, et al. "POS0628 BARICITINIB AMELIORATES BLEOMYCIN-INDUCED PULMONARY AND SKIN FIBROSIS VIA JAK 1/2 INHIBITON." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 588–89. http://dx.doi.org/10.1136/annrheumdis-2023-eular.5329.

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BackgroundSignal transducer and activator of transcription 3 (STAT3) protein is activated in lung fibroblasts and alveolar type II cells (AT-II) and is thought to contribute to fibrosis in lung tissue. Significant JAK/STAT activation was demonstrated in fibroblasts, skin biopsies and scleroderma animal models of patients with Systemic Sclerosis (SSc) [1].ObjectivesThe aim of this study was to determine whether inhibition of JAK2/STAT3 in the experimental model of scleroderma is a potential therapeutic strategy for this disease and to investigate the effects of the JAK 1-2 inhibitor Baricitinib
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Al-Hazragi, Abd-al-Salam, and Assim Lateef. "Behaviour of Uniaxial Reinforced Concrete Columns Strengthened with Ultra-High Performance Concrete and Fiber Reinforced Polymers." Tikrit Journal of Engineering Sciences 28, no. 2 (2021): 54–72. http://dx.doi.org/10.25130/tjes.28.2.05.

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This article investigates the behaviour of strengthened concrete columns using jacketing ultra-high-performance fiber reinforced concrete (UHPFRC) and carbon fiber-reinforced polymer (CFRP) under uniaxial loaded. The jacket was connected to the column core using shear connectors and (CFRP) fixed as a strip on the tension zone between the column cores and the jacketing. Seven column samples of square cross-section (120 x120) mm at the midsection with overall length of 1250 mm were cast using normal strength concrete (NSC) and having similar longitudinal and transverse reinforcement. The samples
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Al-Hazragi, Abd-al-Salam, and Assim Lateef. "Behaviour of Uniaxial Reinforced Concrete Columns Strengthened with Ultra-High Performance Concrete and Fiber Reinforced Polymers." Tikrit Journal of Engineering Sciences 28, no. 2 (2021): 54–72. http://dx.doi.org/10.25130/tjes.28.02.05.

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This article investigates the behaviour of strengthened concrete columns using jacketing ultra-high-performance fiber reinforced concrete (UHPFRC) and carbon fiber-reinforced polymer (CFRP) under uniaxial loaded. The jacket was connected to the column core using shear connectors and (CFRP) fixed as a strip on the tension zone between the column cores and the jacketing. Seven column samples of square cross-section (120 x120) mm at the midsection with overall length of 1250 mm were cast using normal strength concrete (NSC) and having similar longitudinal and transverse reinforcement. The samples
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Armstrong, Derek, Nicole Kirchoff, Maribeth Nicholson, and Mariana Byndloss. "GUT MICROBIOME CHANGES ASSOCIATED WITH INFLIXIMAB RESPONSE IN PEDIATRIC IBD." Inflammatory Bowel Diseases 31, Supplement_1 (2025): S56. https://doi.org/10.1093/ibd/izae282.134.

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Abstract BACKGROUND Infliximab is a first line therapy for severe pediatric IBD, but only 50% of patients achieve and maintain clinical remission by 1 year. We investigated the gut microbiome in pediatric IBD patients to determine its impact on Infliximab response. METHODS 100 pediatric IBD patients on maintenance Infliximab therapy were enrolled and prospectively followed over a two-year period at a tertiary children’s hospital from 2021-2024. Disease activity was evaluated using the Harvey-Bradshaw Index (HBI) in CD patients or the Pediatric Ulcerative Colitis Activity Index (PUCAI) in UC pa
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Novikov, Dmitry, and Anton Derkachev. "Nonequilibrium state of uranium isotopes in the ground waters of the Ob-Zaysan folded area." Sustainable Development of Mountain Territories 17, no. 1 (2025): 313–22. https://doi.org/10.21177/1998-4502-2025-17-1-313-322.

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Introduction. The migration ability of uranium in solution is determined by the form of its location, which is controlled primarily by the geochemical situation, redox conditions of the environment and the presence of water-dissolved organic substances. In a closed system, when the secular equilibrium is reached, the ratio of uranium isotopes 234U/238U (γ) tends to unity. However, in some cases, this balance shifts in a positive direction. Purpose of the research. The purpose of this work is to determine the ratios of 234U/238U activities in groundwater of contrasting hydrogeological environme
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Fernandez, Matthew E., Cory B. Fines, Fatemah S. Subul, et al. "Abstract 2328: Macrophage-targeting immunotherapy for triple negative breast cancer." Cancer Research 83, no. 7_Supplement (2023): 2328. http://dx.doi.org/10.1158/1538-7445.am2023-2328.

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Abstract Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype that lacks targeted treatment options. While immune check point blockade leads to significant benefits in the treatment of TNBC when in combination with chemotherapy, recurrence, metastasis, and drug resistance still remain a major challenge. The purpose of this study was to assess the ability of a colony-stimulating factor 1 receptor inhibitor (CSF-1Ri) to shift the phenotype of the tumor microenvironment (TME) in a mouse model of TNBC, and the potential benefit of such tumor priming when the CSF-1Ri is
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Ropero Gradilla, Paloma, María Menor Gómez, Marta Morado Arias, et al. "Molecular Characterization of Non-Transfusion Dependent Beta-Thalassemia (NTDT) in Spain." Blood 144, Supplement 1 (2024): 5266. https://doi.org/10.1182/blood-2024-197990.

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Introduction In recent years, the clinical classification of beta thalassemia has been based on transfusion needs. Non-transfusion dependent beta-thalassemias (NTDT), previously referred to as thalassemia intermedia, do not require regular transfusions or may not need them at throughout the patient's life, only receiving transfusions in specific clinical situations such as pregnancy, infections, or surgery, etc. These patients represent a very heterogeneous and complex group with various associated Hb abnormalities. Objective Molecular characterization and registry of the cases of non-transfus
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Okam, Maureen, Todd Koch, and Minh Ha Tran. "Clinical Criteria for Transitioning from Oral to IV Iron Replacement Therapy in Patients with Iron Deficiency Anemia." Blood 124, no. 21 (2014): 211. http://dx.doi.org/10.1182/blood.v124.21.211.211.

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Abstract Introduction: Oral iron supplementation is an effective means of iron replacement. Nevertheless, there is a frequent need to transition patients with iron deficiency anemia (IDA) from oral to intravenous (IV) iron therapy for inadequate response. No definitive guidance on the optimal timing for this change in therapy exists. Serum hepcidin may be a marker in predicting response to oral iron therapy, but currently, hepcidin assays are not commercially available. We evaluated the ability of various early response characteristics to accurately predict for an overall hemoglobin (Hb) respo
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Mendonça, Rafaela, Angelica A. Silveira, Fernando Vieira Pericole та ін. "Inflammasome-Dependent IL-1β Release from Neutrophils in Human Sickle Cell Anemia". Blood 128, № 22 (2016): 854. http://dx.doi.org/10.1182/blood.v128.22.854.854.

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Abstract Sickle cell anemia (SCA) is associated with a chronic inflammatory state. The inflammasome complex, responsible for IL-1β and IL-18 cytokine maturation and release, is formed by pattern recognition receptors (PRRs), such as the NLRP3 protein, which recognize damage (or pathogen) associated molecular patterns (DAMPs), in turn recruiting the ASC adapter protein, and cleaving pro-caspase-1, which processes pro-IL-1β and pro-IL-18 into their bioactive forms. While elevated plasma IL-1β and IL-18 levels have been reported in SCA, organization of the inflammasome and its components, and the
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Nero, Alecia C., Theresa Nguyen Kinard, Beverley Adams-Huet, Karen Matevosyan, and Ravindra Sarode. "Determinants of Inter-Procedure Interval in Patients with Sickle Cell Anemia Enrolled a Chronic Red Blood Cell Exchange Program." Blood 124, no. 21 (2014): 4284. http://dx.doi.org/10.1182/blood.v124.21.4284.4284.

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Abstract Background: Sickle cell anemia (SCA) is a genetically inherited disorder that can lead to severe sequelae in any organ system. The most clinically devastating complications, e.g. stroke, are managed with chronic red blood cell (RBC) transfusions as curing the underlying SCA is often not an option. Chronic RBC exchange (RBCx), is an effective alternative to simple transfusions and often performed every 4-5 weeks. Isovolemic Hemodilution-Red Blood Cell Exchange (IHD-RBCx) is a modified RBCx method used at UT Southwestern Medical Center (UTSW) and increases the time interval between tran
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Chen, Jiayin, Kaifeng Liu, Foon-yee Chan, et al. "Usability Testing for Smart IV Pumps Through Simulation-based Evaluation." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 63, no. 1 (2019): 2209–10. http://dx.doi.org/10.1177/1071181319631187.

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Poorly designed user interfaces limit the effective use of medical devices, leading to user errors. Hence, before such devices are implemented, it is essential to identify potential usability issues. A common approach to testing usability is a simulation-based test, which allows practitioners to identify usability issues by observing how users interact with the product being tested. Infusion pumps are frequently used in medical settings, and much effort has been made to advance their design and features. To enhance patient safety, smart intravenous (IV) pumps with safety functions (e.g., drug
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Zhang, Yining, and Hengjin Chen. "Evaluation of degree of blending and its effect to performance of recycled hot-mix asphalt under different preheating conditions." Canadian Journal of Civil Engineering, March 19, 2024. http://dx.doi.org/10.1139/cjce-2023-0389.

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This research comprehensively explored the function of preheating temperature and quantified the contribution of degree of blending (DoB) to performance of recycled HMAs. Five groups were designed, including no blending group, full blending group, and three experimental groups at preheating temperatures of 60 ºC, 110 ºC, and 160 ºC. It can be found that the preheating temperature played a positive impact on DoB and performance of recycled HMAs. As the preheating temperature increased by 50 ºC, about 0.13%~0.2% RAP binder can be additionally activated, and TSR, shear strength, and fracture ener
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Nishizawa, Mitsuhiro, Steven D. Glassman, Mladen Djurasovic, et al. "Impact of Short-term Perioperative Steroid Administration on Outcomes of 1- and 2-Level Transforaminal Lumbar Interbody Fusion." Spine, March 3, 2025. https://doi.org/10.1097/brs.0000000000005321.

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Study Design. Retrospective observational cohort Objective. To assess the impact of short-term perioperative use of systemic steroids on the surgical outcomes of one- to two-level transforaminal lumbar fusion (TLIF), with a primary focus on complications. Summary of Background Data. Steroids are commonly used in the perioperative period, including as a standard anesthesia practice and control for postoperative pain. However, the impact of perioperative use of systemic steroids on the surgical outcomes of lumbar fusion surgery remains unclear. Methods. We retrospectively reviewed 560 patients w
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Dunagan, Kelli Amanda, Annette Monique Washington, Melissa Davis, et al. "Effect of a Mindful Eating Intervention on Lifestyle Factors in Overweight and Obese Postmenopausal Breast Cancer Survivors – a Pilot Study." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.797.18.

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Studies have shown that postmenopausal breast cancer survivors are more likely to be sedentary and have poorer diet quality than their non‐cancer counterparts, contributing to weight gain. In addition, they are more likely to have increased levels of psychological stress. Heightened mindfulness is associated with healthier eating behaviors, lower BMI, and reduced stress. However, little is known about the effect of mindful eating on these lifestyle factors in overweight and obese postmenopausal breast cancer survivors. The objective of the study was to examine the effect of a mindful eating in
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Ishikawa, Takuya, Hiroki Kawashima, Eizaburo Ohno, et al. "Clinical characteristics and long-term prognosis of autoimmune pancreatitis with renal lesions." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-020-79899-3.

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AbstractAutoimmune pancreatitis (AIP) is recognized as the pancreatic manifestation of a systemic IgG4-related disease that can involve various organs, including the kidney. However, renal lesions tend to be overlooked when AIP is diagnosed, and the clinical characteristics and long-term prognosis of AIP with renal lesions are unclear. We retrospectively reviewed 153 patients with AIP diagnosed at our hospital with a median follow-up period of 41 months (interquartile range, 10–86) and classified them into two groups: the KD group (n = 17), with characteristic renal imaging features, and the n
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Kornya, Matthew R., Anthony CG Abrams-Ogg, Shauna L. Blois, and R. Darren Wood. "Determination of clopidogrel effect in cats using point-of-care Plateletworks ADP and shipped samples for PFA-200 analysis in a clinical practice setting." Journal of Feline Medicine and Surgery 26, no. 4 (2024). http://dx.doi.org/10.1177/1098612x241241404.

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Objectives Clopidogrel is the recommended first-line antithrombotic in cats for a variety of conditions; however, it is ineffective in 15–20% of cats. The determination of clopidogrel effectiveness with platelet function assays has historically been limited to specialty centers; however, recent work has suggested that in-hospital or shipped analyses of samples may be feasible. The aim of the present study was to investigate the utility of an in-house analysis and shipping of blood samples collected in primary practices for the determination of clopidogrel effectiveness. Methods Citrated blood
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