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Kim, Jeong Eun, Chul Lee, Kook In Park, Min Soo Park, Ran Namgung und In Kyu Park. „Successful pleurodesis with OK-432 in preterm infants with persistent pleural effusion“. Korean Journal of Pediatrics 55, Nr. 5 (2012): 177. http://dx.doi.org/10.3345/kjp.2012.55.5.177.
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Malakov, Alexander, Sergiy Burlaka und Anatoliy Yelenych. „OPTIMIZATION OF MECHANISM PARAMETERS FLOWERING PLANT WEIGHT MACHINES-TRAILERS TRAILER KPP-4,2“. ENGINEERING, ENERGY, TRANSPORT AIC, Nr. 2(109) (27.08.2020): 48–56. http://dx.doi.org/10.37128/2520-6168-2020-2-5.
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The article proposes a method of parametric synthesis of the device of flattening the plant mass of the mower-flatter of the trailed KPP-4,2. A method of modernization of the parameters of the flattening mechanism has been developed, which can be used in both trailed and self-propelled mowers. It is established that the stability of plant mass flattening through the streets of the planting apparatus directly influences the energy costs of deformation of plant mass and indirectly the magnitude and rate of loss of moisture and nutrients in the flattened mass, which is largely determined by the structure and parameters of the mechanism of flattening (MP). The analytical solution to the design problem of the flattening device KPP-4,2 has an iterative implementation of the analysis procedures based on the formed FMM, as well as the procedures of comparison and selection of options in the procedure of parametric synthesis of MP. It is to choose a combination of internal parameters of the flattening device, according to the selected structure of the MP, which, while satisfying the functional constraints, simultaneously stabilizes the pressure from the upper to the lower roller. The analytical dependences of the operation of the trailed mower-conditioner KPP-4.2 on the height, density of grass stand, culture, agrotechnical requirements, field topography and physical and chemical composition of the soil have been established. Depending on the listed factors, the initial data and coefficients used in modeling change. As a result, we obtain the corresponding dependencies, show how the productivity and useful work of the mower changes from changes in the environmental parameters of the mowed mass and operating modes. Directly from the data obtained, it is possible to recommend the operating modes of the mower to obtain maximum performance on a particular background of work. As a result, we received optimization data to improve the operation of the trailed mower-conditioner KPP-4,2 taking into account all variables and coefficients.
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Veselovska, Natalia, Alexander Malakov und Sergiy Burlaka. „MATHEMATICAL MODELING OF THE MECHANISM POST-TRAILED KPP-4.2“. ENGINEERING, ENERGY, TRANSPORT AIC, Nr. 4(107) (20.12.2019): 5–10. http://dx.doi.org/10.37128/2520-6168-2019-4-1.
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Maintaining the required cut height minimizes losses and ensures continuous shoe contact with the surface. Thus the excessive pressure of the shoe destroys the stubble and leads to its accelerated wear, and insufficient pressure is accompanied by increased losses and provokes the galloping of the header. An analytical solution to the problem of modeling the mechanism of the KPP-4.2 hanging is an iterative execution of the analysis procedures based on the formed hypothesis, as well as the procedures of comparison and selection of options in the procedure of parametric synthesis. It is a choice of a combination of internal parameters of the flattening device, which, while satisfying the functional limitations, simultaneously stabilize the whole mechanism. A study and analysis of the hanging mechanism of a mower-conditioner trailed KPP-4.2 using methods of theoretical mechanics, differential and integral calculus, probability theory, mathematical modeling and computer software. A geometric model has been created for calculating and optimizing the operation of the hanging mechanism. The MVA KPP-4.2 output parameters were calculated for three different cut heights.
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Vu, Giap Van, Chau Quy Ngo, Phuong Thu Phan, Lan Phuong Thi Doan, Toan Thi Nguyen, Mai Hong Nguyen, Diep Ngoc Nguyen et al. „Inadequate Knowledge, Attitude and Practices about Second-Hand Smoke among Non-Smoking Pregnant Women in Urban Vietnam: The Need for Health Literacy Reinforcement“. International Journal of Environmental Research and Public Health 17, Nr. 10 (25.05.2020): 3744. http://dx.doi.org/10.3390/ijerph17103744.
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The rate of exposure to second-hand smoke (SHS) is relatively high in several countries, including Vietnam, and health issues related to SHS have worsened in recent years, especially for pregnant women and their infants. Enhancement of knowledge, attitude, and practice (KAP) scores of pregnant women in Vietnam could raise practical interventions to protect their health and reduce complications of SHS. A cross-sectional study of 432 pregnant women who came to the Obstetrics Department of Bach Mai Hospital, Hanoi, Vietnam for antenatal care was conducted in 2016 to collect information about their KAP related to SHS. Composite mean scores from survey questions assessing their KAP were calculated on a 10-point scale, finding mean scores of 4.19, 7.45, and 4.30, respectively. Higher scores indicated better knowledge, attitude, and practice. Generalized linear models identified that age, occupation, living place, and sources of information were associated with SHS-related KAP. Findings from this study indicate that suitable programs related to SHS should be implemented to improve and reinforce health literacy to both mothers and smokers to reduce the harmfulness of smoking on women and their infants’ health.
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Sup, Devid Frastiawan Amir, Setiawan Bin Lahuri, Imam Kamaluddin, Mohammad Ghozali und Iman Nur Hidayat. „Tipologi Koperasi Umum dan Syariah“. Al-Intaj : Jurnal Ekonomi dan Perbankan Syariah 8, Nr. 2 (29.09.2022): 251. http://dx.doi.org/10.29300/aij.v8i2.6327.
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This study aims to typify cooperatives in Ponorogo, East Java, Indonesia. The data used as the object of the typology are 842 cooperative data. This study used a quantitative descriptive methodology with a typology approach. Data were collected using the documentation method and typologically using the descriptive analysis method. The results obtained are that there are 430 cooperatives that have been certified by NIK certtified and 412 cooperatives that have not been certified by NIK certified. Cooperatives in Ponorogo, East Java, Indonesia can be typified into 4 (four): (1) Based on level (primary cooperative, secondary cooperative, and cooperative center); (2) Based on activity (KSP, KSU, KBPR, producer cooperative, consumer cooperative, service cooperative, and handicraft industry cooperative); (3) Based on member (KPN-KPRI, employee cooperative, student cooperative, KUD, women's cooperative, and market cooperative); (4) Sharia entities (sharia cooperative, KJKS-KSPPS, Kopontren, and BMT).
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Rau, Franco. „Problematisierung der Praxis und Forschungsstand“. MedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung, Lernsituationen m. Metaphern & W (03.07.2020): 125–303. http://dx.doi.org/10.21240/mpaed/diss.fr/2020.07.03.x.
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Im dritten Teil dieser Arbeit erfolgt eine Problematisierung der Praxis sowie die Darstellung des Forschungsstandes für zwei ausgewählte Schwerpunkte. Der erste Schwerpunkt fokussiert den Stand der Medienbildung im Lehramtsstudium (Kap. 4). Der zweite Schwerpunkt widmet sich den erziehungswissenschaftlichen Studienanteilen als Handlungs- und Forschungsfeld des vorliegenden Projektes (Kap. 5). In vergleichender Betrachtung bildungspolitischer Leitbilder und der aktuellen Praxis werden jeweils konkrete Probleme benannt und potenzielle Gestaltungsspielräume markiert (Kap. 4.2, 5.2). Zur Vorbereitung eines theoretisch und empirisch begründeten Entwurfs von Lernsituationen zur integrativen Medienbildung erfolgt zum einen eine theoretisch-begriffliche Verortung medienpädagogischer Begriffe (Kap. 4.3) sowie eine Betrachtung des aktuellen Forschungs- und Diskussionsstandes zu den Themenfeldern «soziale Medien als Mittel zur Gestaltung von Hochschullehre» (Kap. 4.4) und «soziale Medien als Gegenstand universitärer Medienbildung» (Kap. 4.5). Zum anderen erfolgt zur Berücksichtigung des Handlungs- und Forschungsfeldes eine Betrachtung von theoretischen und empirischen Ansätzen zur Erfahrung-Theorie-Relationierung im Rahmen der erziehungswissenschaftlichen Studienanteile (Kap. 5.3). Es werden die Potenziale von Metaphern als Forschungskonstrukt und Reflexionsmöglichkeit in der Lehrerinnen- und Lehrerbildung (Kap. 5.4) sowie in weiteren pädagogischen Kontexten (Kap. 5.5) vorgestellt und hinsichtlich ihrer Relevanz für die vorliegende Arbeit diskutiert.
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Katičić Bogdan, Ida, Davorin Kajba und Saša Bogdan. „Varijabilnost klonova u proizvodnji žira i njezin učinak na efektivne veličine populacija i genetsku raznolikost potomstva u klonskim sjemenskim plantažama hrasta lužnjaka (Quercus robur L.) u Hrvatskoj“. Šumarski list 143, Nr. 3-4 (24.04.2019): 111–22. http://dx.doi.org/10.31298/sl.143.3-4.2.
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U ovom radu željeli smo ispitati različite parametre koji nam daju informaciju o učinkovitosti plantaža u proizvodnji genetski raznolikog potomstva. Koristili smo raspoložive inventurne podatke tvrtke “Hrvatske šume” d.o.o. o brojnom stanju i starosti rameta, te zabilježenim urodima u dvije klonske sjemenske plantaže hrasta lužnjaka; KSP “Plešćice” i KSP “Petkovac”. U slučaju KSP „Plešćice” korišteni su inventurni podaci, te podaci o urodu za 2003.,2006.,2007.,2008.,2009. i 2010. godinu. Nakon 2010. godine zbog organizacijskih se razloga prestalo pratiti urod po klonovima i prešlo se na evidentiranje ukupnog uroda na plantaži, pa je za period 2010.-2017. godine nemoguće procjeniti genetsku raznolikost uroda. U slučaju KSP „Petkovac” korišteni su inventurni podaci, te podaci o urodu za 2003.,2004.,2005.,2006.,2008.,2009. i 2010. godinu. U slučaju KSP „Petkovac” također se nakon 2010. godine napustilo evidentiranje uroda po klonovima. Količine i varijabilnost uroda žira po godinama, kao i projekcije uroda za 2018. i 2019. godinu na temelju polinomijalnih regresijskih krivulja izračunali smo za sve godine evidentiranog uroda za cijelo razdoblje 2003. – 2017. godina. Rezultati su prikazani u tablici 1 i na slikama 1 i 2. Sve druge analize bile su moguće samo za godine kada se sakupljanje žira u plantažama provodilo odvojeno po klonovima. Korelacijama po metodama Pearsona i Spearmana usporedili smo raspodjelu uroda žira između parova istraživanih godina po klonovima, odnosno poredak udjela klonova u urodima žira između istraživanih godina. Obje korelacije bile su većinom statististički značajne između parova godina, sa ponekim iznimkama (tablica 2). Ravnoteža uroda klonova po godinama, opisana kumulativnim krivuljama proizvodnje žira po godinama, po postocima rodnih klonova, prikazana je na slikama 3 i 4. Krivulje ravnoteže uroda klonova za obje plantaže prikazuju izrazito neravnomjernu raspodjelu uroda po klonova, što znači da je manjina klonova u istraživanim godinama doprinosila većinskom količinom uroda. U uvjetima jednake plodnosti i sinkroniziranosti klonova doprinos u urodu bio bi razmjeran zastupljenosti klonova (clone size) tj. klonovi s većim brojem rameta značajnije bi doprinosili urodu. Iz tablice 3. može se primjetiti da je u slučaju KSP “Plešćice” ova korelacija bila slabija nego kod KSP “Petkovac”. Dapače, u tri od šest promatranih godina ona uopće nije bila značajna. U slučaju KSP “Petkovac” korelacija je bila značajna u svim promatranim godinama Procjena efektivnih veličina populacije i genetske raznolikosti potomstva po godinama prikazani su u tablici 4. isključivo za žensku plodnost klonova. Prilikom izračuna doprinosa oba roditelja muška plodnost procijenjena je pomoću tri scenarija koja obuhvaćaju raznolik raspon potencijalnog muškog doprinosa u efektivnoj veličini populacije. Rezultati su prikazani u tablici 5. Usporedbom tri scenarija muškog doprinosa ukupnom efektivnom tj. statusnom broju (Np) vidljivo je da su vrijednosti za prvi ,gdje je muški doprinos razmjeran udjelu rameta datog klona u ukupnom broju rameta, intermedijarne u odnosu na druga dva scenarija. Najniži efektivni brojevi roditelja (Np), a time i najniži relativni efektivni brojevi (Nr), te najviše vrijednosti koeficijenta grupnog srodstva (Θ) dobivene su za drugi scenarij u kojem je muški doprinos jednak ženskome. Te su vrijednosti identične vrijednostima za samo žensku plodnost. Najviši su efektivni brojevi i analogno druge vrijednosti dobivene za treći scenarij u kojem se pretpostavlja jednak muški doprinos svih klonova. Za obje plantaže korelacija poretka ženskih efektivnih brojeva klonova za pojedine godine uroda, sa poretkom za količine uroda tih godina (po metodi Spearmana) je statistički značajna na razini p < 0,05. Za primjenu mjera procjene genetske raznolikosti proizvedena u klonskim sjemenskim plantažama potrebna su sukcesivna višegodišnja praćenja cvjetanja/uroda, kao i saznanja o genetskoj dobiti dobivena testiranjem potomstva i uzgojne vrijednosti klonova u nedavno postavljenim testovima potomstva iz plantaža. Zbog svega toga je apsolutno preporučljivo da se daljnje sakupljanje uroda u ovim klonskim sjemenskim plantaža obavlja odvojeno po klonovima, jer se jedino na taj način, bez skupih molekularnih analiza, može doći do relevantnih informacija o doprinosu pojedinih klonova genetskoj raznolikosti potomstva.
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ISHIJIMA, Hiroshi, Kyoya FUKUDA, Kensuke MATSUBARA und Mizuhiko HOSOKAWA. „Production of 423-nm Second-Harmonic Generation Light Beam Using pp-KTP Crystal“. Review of Laser Engineering 35, Nr. 4 (2007): 273–76. http://dx.doi.org/10.2184/lsj.35.273.
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Bayu Kusuma, Kadek, Cok Gede Indra Partha und I. Wayan Sukerayasa. „PERANCANGAN SISTEM POMPA AIR DC DENGAN PLTS 20 kWp TIANYAR TENGAH SEBAGAI SUPLAI DAYA UNTUK MEMENUHI KEBUTUHAN AIR MASYARAKAT BANJAR BUKIT LAMBUH“. Jurnal SPEKTRUM 7, Nr. 2 (04.06.2020): 46. http://dx.doi.org/10.24843/spektrum.2020.v07.i02.p7.
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Karangasem Regency, especially in Kubu Subdistrict, Tianyar Tengah Village, Banjar BukitLambuh, is an area that still lacks clean water, so that villagers still rely on purchasing clean waterthrough tank trucks at high prices. Around Banjar Bukit Lambuh, there is a 20 kWp Central TianyarPLTS which has been abandoned since 2016 due to the absence of regional companies that manageand maintain the PLTS so that some components of the PLTS are damaged. The abandonment of the20 kWp PLTS makes the Bali Provincial Manpower and Energy Department (ESDM) Department planto transfer the function of PLTS as a source of electricity for water pumps that lift water fromreservoirs with a water capacity of 72,000 liters to a 30,000 liter water reservoir which is near thePLTS to meet the water needs of residents in the Middle Tianyar Village Banjar Bukit Lambuh. Theselected water pump type Lorentz PS2-4000 C-SJ3-32 submersible DC with a total head of 108.6meters and a pipe length of 1,640 meters and requires power of 2.96 kW supplied from PLTS 20 kWpTianyar Tengah with a cable length of 1,640 meters and voltage drop of 8,183 volts, so that the pumpcan operate for 7 hours with 4.2 m3 / h water discharge producing 29,400 liters of water that can meetthe water needs of residents of Banjar Bukit Lambuh Village by 23,328 liters per day.
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McLEOD, J. G., und J. M. CLARKE. „EFFECT OF HARVEST TIME AND DRYING METHOD ON QUALITY AND GRADE OF WINTER RYE“. Canadian Journal of Plant Science 67, Nr. 2 (01.04.1987): 417–24. http://dx.doi.org/10.4141/cjps87-060.
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Three winter rye (Secale cereale L.) cultivars, Cougar, Puma and Musketeer, were grown in a field experiment for 2 yr to determine the effects of kernel water concentration (KWC) at harvest time and drying method on final quality and grade of the grain. Plots were harvested when KWC was in the range of 950–100 g water kg−1 kernel dry weight. Grain was dried in windrows in the field and artificially in a forced-air oven at 40–45 °C. Kernel water concentration at harvest, test mass, kernel mass, falling number and germination were determined. Test mass increased as KWC at harvest decreased, especially in the artificially dried treatments. Kernel mass was lower when harvested at high KWC, especially in the windrowed treatments. Falling numbers were affected by harvest time and drying method, but trends were not clear. Germination was reduced by artificial drying at KWC greater than 430 g kg−1. Grades were not affected by windrowing at KWC up to 957 g kg−1. Artificial drying reduced commercial grades, especially at high KWC. The main degrading factors were presence of immature kernels and low test mass.Key words: Test mass, artifical drying, windrow, germination, falling number, harvest time
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Dewi, Nadia Cintya, Leli Nisfi Setiana und Aida Azizah. „ALIH KODE DAN CAMPUR KODE PADA TUTURAN FILM PENDEK �KTP� OLEH BALAI PENGEMBANGAN MEDIA TELEVISI PENDIDIKAN DAN KEBUDAYAAN (BPMPT) DAN RELEVANSINYA PADA PEMBELAJARAN BAHASA INDONESIA DI SMA“. Jurnal Pendidikan Bahasa Indonesia 8, Nr. 1 (01.07.2020): 49. http://dx.doi.org/10.30659/j.8.1.49-69.
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Penelitian ini mengenai alih kode dan campur kode pada film pendek �KTP� oleh BPMPT dan merelevansikannya pada pembelajaran bahasa Indonesia di SMA dengan media video. Masalah yang dikaji dalam penelitian ini adalah wujud alih kode dan campur kode dalam film pendek �KTP� oleh BPMPT serta relevansinya pada pembelajaran bahasa Indonesia di SMA.Penelitian ini merupakan penelitian kualitatif. Data dalam penelitian ini berupa tuturan tokoh dalam film pendek �KTP�, sedangkan sumber data diambil dari video film pendek �KTP� yang berdurasi 15 menit 32 detik. Teknik pengumpulan data yang digunakan� yaitu teknik simak bebas libat cakap kemudian teknik catat.Berdasarkan hasil analisis data yang diperoleh maka dapat menghasilkan penelitian sebagai berikut. Pertama, bentuk alih kode dan campur kode pada tuturan film pendek �KTP� oleh BPMPT yaitu terdapat 3 alih kode yaitu dari bahasa Indonesia ke bahasa Jawa dan 25 campur kode dari bahasa Indonesia ke bahasa Jawa dan Inggris.. Kedua, Relevansi film pendek �KTP� oleh BPMPT dinyatakan relevan terhadap pembelajaran bahasa Indonesia di SMA kelas X semester 1 dengan KD 4.2 yaitu Mengonstruksi teks laporan hasil observasi dengan memerhatikan isi dan aspek kebahasaan. Relevansi tersebut bisa dijadikan sebagai bahan pembelajaran bahasa Indonesia di SMA dengan media video (audio dan visual).
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Bellafronte, Elisangela, Tatiane Casagrande Mariguela, Luiz Henrique Garcia Pereira, Claudio Oliveira und Orlando Moreira-Filho. „DNA barcode of Parodontidae species from the La Plata river basin - applying new data to clarify taxonomic problems“. Neotropical Ichthyology 11, Nr. 3 (September 2013): 497–506. http://dx.doi.org/10.1590/s1679-62252013000300003.
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In the past years, DNA barcoding has emerged as a quick, accurate and efficient tool to identify species. Considering the difficulty in identifying some Parodontidae species from the La Plata basin and the absence of molecular data for the group, we aimed to test the effectiveness of DNA barcoding and discuss the importance of using different approaches to solve taxonomic problems. Eight species were analyzed with partial sequences of Cytochrome c oxidase I. The mean intraspecific K2P genetic distance was 0.04% compared to 4.2% for mean interspecific K2P genetic distance. The analyses of distance showed two pairs of species with K2P genetic divergence lower than 2%, but enough to separate these species. Apareiodon sp. and A. ibitiensis, considered as the same species by some authors, showed 4.2% genetic divergence, reinforcing their are different species. Samples of A. affinis from the Uruguay and Paraguay rivers presented 0.3% genetic divergence, indicating a close relationship between them. However, these samples diverged 6.1% from the samples of the upper Paraná River, indicating that the latter represents a potentially new species. The results showed the effectiveness of the DNA barcoding method in identifying the analyzed species, which, together with the morphological and cytogenetic available data, help species identification.
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Vahaboglu, H., R. Oztürk, G. Aygün, F. Coşkunkan, A. Yaman, A. Kaygusuz, H. Leblebicioglu, I. Balik, K. Aydin und M. Otkun. „Widespread detection of PER-1-type extended-spectrum beta-lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: a nationwide multicenter study.“ Antimicrobial Agents and Chemotherapy 41, Nr. 10 (Oktober 1997): 2265–69. http://dx.doi.org/10.1128/aac.41.10.2265.
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We studied the prevalence and molecular epidemiology of PER-1-type beta-lactamases among Acinetobacter, Klebsiella, and Pseudomonas aeruginosa strains isolated over a 3-month period in eight university hospitals from distinct regions of Turkey. A total of 72, 92, and 367 Acinetobacter, Klebsiella, and P. aeruginosa isolates were studied, respectively. The presence of blaPER was determined by the colony hybridization method and later confirmed by isoelectric focusing. We detected PER-1-type beta-lactamases in 46% (33/72) of Acinetobacter strains and in 11% (40/367) of P. aeruginosa strains but not in Klebsiella strains. PER-1-type enzyme producers were highly resistant to ceftazidime and gentamicin, intermediately resistant to amikacin, and susceptible or moderately susceptible to imipenem and meropenem. Among PER-1-type-beta-lactamase-positive isolates, five Acinetobacter isolates and six P. aeruginosa isolates from different hospitals were selected for ribosomal DNA fingerprinting with EcoRI and SalI. The EcoRI-digested DNAs were later hybridized with a digoxigenin-labelled PER-1 probe. The ribotypes and the lengths of blaPER-carrying fragments were identical in four Acinetobacter strains. A single isolate (Ac3) harbored a PER gene on a different fragment (approximately 4.2 kbp) than the others (approximately 3.4 kbp) and showed a clearly distinguishable ribotype. Ribotypes of P. aeruginosa strains obtained with EcoRI showed three patterns. Similarly, in Pseudomonas strains two different EcoRI fragments harbored blaPER (approximately 4.2 kbp in five isolates and 3.4 kbp in one isolate). PER-1-type beta-lactamases appear to be restricted to Turkey. However, their clonal diversity and high prevalence indicate a high spreading potential.
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Kalasauskienė, Aurija, Eglė Drebickaitė und Gabrielė Legotaitė. „Keratokonusas: 14-kos metų kiaurinės keratoplastikos ankstyvųjų pooperacinių rezultatų apžvalga“. Sveikatos mokslai 26, Nr. 4 (26.09.2016): 26–30. http://dx.doi.org/10.5200/sm-hs.2016.053.
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Keratokonusas – viena dažniausių kiaurinės keratoplastikos (KKP) priežasčių pasaulyje. Serga jauni, darbingo amžiaus žmonės, todėl pažengus ligai (vėlyvoje stadijoje), kai kiti gydymo metodai neefektyvūs, KKP gali grąžinti regą. Pastebėta, kad po donorinės ragenos persodinimo komplikacijų pasitaiko, tačiau dauguma recipientų patenkinti pooperaciniu rezultatu. Siekdami įvertinti dėl keratokonuso atliekamų KKP dažnį išanalizavome per 14-lika metų (2001-2014 m.) LSMUL KK Akių ligų klinikoje operuotų ligonių atvejus. Šiame straipsnyje aptarsime KKP dažnį, kai donorinės ragenos persodinimo priežastis - keratokonusas, sergančiųjų pasiskirstymą pagal amžių, lytį, pažeistą akį, taip pat ankstyvuosius pooperacinius rezultatus (regos aštrumo pokytį, pooperacinę eigą, komplikacijas), kataraktos ir glaukomos bei amžiaus reiškmę regos aštrumo pokyčiui. Retrospektyvinis tyrimas vykdytas gavus Bioetikos centro leidimą (Nr. BEC-MF-623). Nustatyta, kad 2001-2014 metais KKP dėl keratokonuso atlikta 71 akyje (24,83 proc.). 59 recipientams persodinta donorinė ragena vienoje akyje, 6 – abiejose akyse. Transplantacijų pasiskirstymas pagal pažeistą akį statistiškai reikšmingai nesiskiria (p=0,635): dešinės akies keratoplastika - 33 ligoniams (46,5 proc.), kairės – 38 ligoniams (53,5 proc.). 19 (26,8%) moterų, kurių amžiaus mediana 39 (27-46) metai ir 52 (73,2%) vyrai, amžiaus mediana 28,5 (25-36) metai. Imtyje vyrų buvo statistiškai reikšmingai daugiau nei moterų (p<0,001). Vyrų ir moterų amžius statistiškai reikšmingai skiriasi (p < 0,019). Nustatyta, kad po ragenos persodinimo 95,8 proc. recipientų regos aštrumas pagerėjo: nežymiai – 32,4 proc., vidutiniškai – 50,7 proc., ženkliai – 12,7 proc. Tik 4,2 proc. recipientų regos aštrumas nepakito ar net pablogėjo. Sklandi pooperacinė eiga (be užfiksuotų komplikacijų) buvo 40 (56,3 proc.) recipientų. 31 tiriamajam (43,7 proc.) stebėtos įvairios komplikacijos. Iš viso diagnozuoti 58 komplikacijų atvejai: 21 recipientui nustatyta viena iš komplikacijų, likusiems - dvi ir daugiau. Ragenos atmetimo reakcija – 14 (24,1proc.) recipientų, ragenos paburkimas – 13 (22,5 proc.) recipientų, siūlės (-lių) atsipalaidavimas – 12 (20,7 proc.) recipientų, akispūdžio padidėjimas – 8 (13,8 proc.) recipientų, transplantato vaskuliarizacija – 5 (8,6 proc.) recipientams, descemeto membranos raukšlės – 4 (6,9 proc.) recipientams, infiltracija apie siūles – 2 (3,4 proc.) recipientams. 2001-2014 metais LSMUL KK Akių ligų klinikoje 24,8 proc. KKP operacijų atlikta dėl keratokonuso. KKP dešinėje ir kairėje akyse atliktos vienodai dažnai (46,5 proc. v.s. 53,5 proc., p>0,635). Donorinės ragenos persodinimo operacija dėl keratokonuso dažniau taikyta vyrams nei moterims (73,2proc. vs. 26,8 proc., p<0,001) ir atlikta 10,5 metų jaunesniame amžiuje (p<0,019). Po kiaurinės keratoplastikos 95,8 proc. atvejų regos aštrumas pagerėjo ir tik 4,2 proc. nepakito, ar net pablogėjo. Jokių komplikacijų nebuvo 40 (56,3 proc.) recipientų. Dažniausia komplikacija - ragenos atmetimo reakcija (24,1 proc.).
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Santos, Adriano José dos, Shirley Verônica Melo Almeida Lima, Alvaro Francisco Lopes de Sousa, Aytana Vasconcelos dos Santos, Israel Gomes de Amorim Santos, Márcio Bezerra Santos, Vera Lucia Corrêa Feitosa et al. „Knowledge, Attitude and Practices towards the Prevention of Schistosomiasis Mansoni in an Endemic Area of Alagoas, Northeast Brazil“. Tropical Medicine and Infectious Disease 8, Nr. 1 (03.01.2023): 34. http://dx.doi.org/10.3390/tropicalmed8010034.
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We analyzed the knowledge, attitudes and practices (KAP) of schistosomiasis mansoni prevention in an endemic area of Brazil. This cross-sectional study was conducted between March and May 2021, with 412 participants living in the municipality of Feira Grande, Alagoas, Brazil. Data collection occurred through visits to the Health Center Urbano II and Massapê, through an interview with a structured questionnaire to identify the levels of KAP regarding schistosomiasis prevention. Of all respondents, 70.87% lived in rural areas, 22.66% reported a history of past schistosomiasis and 52.71% never participated in schistosomiasis control program actions. Factors associated with better KAP scores were being part of an older age group, not using rainwater and having no history of past schistosomiasis. Specifically, among the domains, attitude was the highest score and knowledge was the lowest. Participation in a health intervention program, knowing someone who had schistosomiasis and having been informed through a public health program seemed to have an important impact on the population’s KAP. Our results contributed to broadening perceptions about schistosomiasis prevention, highlighting the positive impacts that health programs and interventions have on disease control.
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Malik, Muhammad Shaukat, und Maria Kanwal. „Impacts of organizational knowledge sharing practices on employees’ job satisfaction“. Journal of Workplace Learning 30, Nr. 1 (12.02.2018): 2–17. http://dx.doi.org/10.1108/jwl-05-2016-0044.
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Purpose The purpose of this paper is to investigate empirically impacts of organizational knowledge-sharing practices (KSP) on employees’ job satisfaction (JS), interpersonal adaptability (IA) and learning commitment (LC). Indirect effects of KSP on JS are also confirmed through mediating factors (LC and IA). Design/methodology/approach Self-administered questionnaire was used for data collection. Knowledge workers from service sector organizations were taken as population of study. Therefore, three types of institutes (banks, insurance and telecom companies) from services sector of Pakistan were selected for sampling purpose. A sample size of 435 employees, comprising 145 employees from each type of institute, was selected. Linear regression analysis and mediation analyses were performed for statistical analysis. Findings Organizational support for knowledge sharing fosters learning commitment (LC), and interpersonal adaptability (IA) among workforce that ultimately grounds employees’ job satisfaction. Therefore, in our findings, the mediating role of IA is greater than the mediating effect of LC. Research limitations/implications This study presents a firm reasoning to decision makers for implementation of KSP in the organizations. Findings of study offer several subjects for discussion in the field of KS by academics and research. Present research is limited to test the composite effect of KSP for some selected employee outcomes only. Originality/value This research attempts to provide empirical evidence about impacts of KSP on employee outcomes. Research work on such issues was lacking in Pakistani context. Therefore, this paper supplies ample of theoretical base for future research as well as management decision makers to maximize the benefits of implementing KSP at their organizations.
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Erdem, Onur, Musa Ay, Asena Yalcin, Sadık Bilgic, Umman Sanlıdilek, Basri Amasyalı, Tanzer Sancak und Turan Olgar. „PATIENT AND STAFF DOSES FOR VARIOUS INTERVENTIONAL RADIOLOGY AND CARDIOLOGY EXAMINATIONS IN TURKEY“. Radiation Protection Dosimetry 198, Nr. 3 (Februar 2022): 158–66. http://dx.doi.org/10.1093/rpd/ncac006.
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Abstract This study aims to determine the radiation doses of patients and staff during different interventional radiology and cardiology examinations. Dose measurements for interventional radiology examinations were performed in Ibn-i Sina Hospital of Ankara University using Siemens Artis-Zee medical imaging system. Patient dose measurement was carried out for interventional cardiology examinations in Cardiology Department of TOBB-ETU University, Medical Faculty Hospital using Philips Allura Centron interventional X-ray system. Patient doses were obtained in terms of kerma area product (KAP) and cumulative air kerma (CAK) from KAP meter attached to the angiography system. Performance tests of the angiography system were performed before patient dose measurements. Staff dose measurements were carried out with thermoluminescence dosimeters (TLD-100) placed in certain areas on the staff. Patient dose measurements were performed for 15 different interventional radiology examinations on a total of 431 patients and for four different cardiology examinations on a total of 299 patients. Monte Carlo based PCXMC 2.0 program was used to calculate patient effective doses. Lower extremity arteriography was the most common examination with a mean KAP value of 30 Gy cm2 and mean effective dose value of 1.2 mSv for total number of 194 patients. Mean KAP values calculated for coronary angiography, percutaneous coronary intervention, electrophysiological procedures and radiofrequency cardiac ablation examinations were 62.8, 162.8, 16.7 and 70.6 Gy cm2, respectively. Radiologist, nurse and technician effective dose normalised to the unit KAP of patient dose were 0.15, 0.11 and 0.14 μSv Gy−1 cm−2. Similarly, cardiologist, nurse and technician effective dose normalised to the unit KAP of patient dose were 0.22, 0.15 and 0.09 μSv Gy−1 cm−2. Measured KAP and CAK values vary depending on the type and complexity of the examination. The measured staff doses during cardiac examinations were higher when compared with that measured for interventional radiology as expected.
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Agatova, Anna, Roman Nepop, Andrey Nazarov, Ivan Ovchinnikov und Piotr Moska. „Climatically Driven Holocene Glacier Advances in the Russian Altai Based on Radiocarbon and OSL Dating and Tree Ring Analysis“. Climate 9, Nr. 11 (31.10.2021): 162. http://dx.doi.org/10.3390/cli9110162.
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Analysis of new chronological data, including 55 radiocarbon, 1 OSL, and 8 dendrochronological dates, obtained in the upper reaches of trough valleys within the Katun, North Chuya, South Chuya, and Chikhachev ranges, together with the 55 previously published ones, specifies climatically driven glacier dynamic in the Russian Altai. Available data refute the traditional concept of the Russian Altai Holocene glaciations as a consecutive retreat of the Late Pleistocene glaciation. Considerable and prolonged warming in the Early Holocene started no later than 11.3–11.4 cal kBP. It caused significant shrinking or even complete degradation of alpine glaciers and regeneration of forest vegetation 300–400 m above the modern upper timber limit. Stadial advances occurred in the middle of the Holocene (4.9–4.2 cal kBP), during the Historical (2.3–1.7 cal kBP), and the Aktru (LIA thirteenth–nineteenth century) stages. New radiocarbon ages of fossil soils limited glaciers expansion in the Middle Holocene by the size of the Historical moraine. Lesser glacial activity between 5 and 4 cal kBP is also supported by rapid reforestation in the heads of trough valleys. Glaciers advance within the Russian Altai, accompanied by accumulation of the Akkem moraine, could have occurred at the end of the Late Pleistocene.
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Sohn, Woon-Mok, Byoung-Kuk Na, Shin-Hyeong Cho, Cheon-Hyeon Kim, Min-Ah Hwang, Kyeong-Woo No und Jai-Dong Kim. „Survey of Zoonotic Trematode Metacercariae in Fish from Water Systems of Geum-gang (River) in Republic of Korea“. Korean Journal of Parasitology 59, Nr. 1 (19.02.2021): 23–33. http://dx.doi.org/10.3347/kjp.2021.59.1.23.
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The infection status of zoonotic trematode metacercariae (ZTM) was surveyed in freshwater fishes from the water systems of Geum-gang (River) in the Republic of Korea (Korea). A total of 1,161 freshwater fishes from 6 local sites of Geum-gang were examined with the artificial digestion method for 4 years (2012-2015). Clonorchis sinensis metacercariae were detected in 122 (37.2%) out of 328 fishes in the positive fish species from 4 surveyed areas, and their mean intensity was 43 per fish infected. Metagonimus spp. metacercariae were found in 432 (51.7%) out of 835 fishes in the positive fish species from all 6 surveyed areas, and their mean intensity was 30 per fish infected. Centrocestus armatus metacercariae were detected in 285 (75.0%) out of 380 fishes in the positive fish species from 6 surveyed areas, and their mean intensity was 2,100 per fish infected. Echinostoma spp. metacercariae were found in 56 (19.7%) out of 284 fishes in the positive fish species from 5 surveyed areas, and their mean intensity was 10 per fish infected. Clinostomum complanatum metacercariae were detected in 98 (57.3%) out of 171 fishes in the positive fish species from only 2 surveyed areas, and their mean intensity was 11 per fish infected. Conclusively, the endemicity of ZTM is not so high in fishes from water systems of Geum-gang in Korea although it is more or less different by fish species, surveyed areas and ZTM species.
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Saelim, Jureeporn, Somsook Santibenchakul und Unnop Jaisamrarn. „Comparison of the knowledge, attitudes toward, and practices of contraception between Thai Muslim women living in Bangkok and those living in the southernmost provinces of Thailand“. Asian Biomedicine 10, Nr. 4 (31.01.2017): 351–59. http://dx.doi.org/10.5372/1905-7415.1004.498.
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Abstract Background There are limited data on the use of contraception by Thai Muslim women. Objectives To compare and explore the knowledge, attitudes toward, and practices (KAP) of contraception between Thai Muslim women living in Bangkok and those living in the Southernmost provinces. Variables associated with KAP were also examined. Methods This was a community-based cross-sectional study, which was conducted in the Muslim communities in Bangkok and those in the southernmost provinces of Thailand including Yala, Pattani, and Narathiwat. A multistage, cluster sampling technique was used to identify participants. Only literate Thai Muslim women who lived in their hometown, and aged between 15–49 years were included in the analysis. A self-administered questionnaire was used to assess participants’ KAP of contraception. Results Data from 423 participants were analyzed. Knowledge and attitude scores between the two groups were comparable. A higher proportion of women from the southernmost provinces used contraceptives. However, when a multivariate regression model was used to adjust for other variables, women’s geographical residence was not associated with higher knowledge and attitude scores, or contraceptive practices. College-level education and higher income level were independent factors associated with contraceptive knowledge. A higher knowledge score was independently related to a positive attitude towards contraception. Only number of children and income level were independently associated with contraceptive practices. Conclusions For Thai Muslim women, geographical residence was not significantly associated with KAP of contraception. The educational level, income level, and number of children of the women played major roles in KAP of contraception.
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Chen, Feng, Hui Hu, Qing-Ming Lu, Ke-Ming Wang, Fei Lu, Bo-Rong Shi und Ding-Yu Shen. „Refractive index profiles of MeV phosphor ion implanted planar waveguide in KTP“. Applied Surface Science 183, Nr. 1-2 (November 2001): 39–42. http://dx.doi.org/10.1016/s0169-4332(01)00546-3.
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Ying, Minju, Yueyuan Xia, Yuming Sun, Qingming Lu, Mingwen Zhao und Xiangdong Liu. „Study of the plasma produced from laser ablation of a KTP crystal“. Applied Surface Science 207, Nr. 1-4 (Februar 2003): 227–35. http://dx.doi.org/10.1016/s0169-4332(02)01368-5.
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Vohra, Rajaat, Anusha Vohra und Meghna Verma. „Poor Knowledge, Attitude and Practices of Pharmacovigilance among Health Care Professionals: A Cross-sectional Study“. Journal of Mahatma Gandhi University of Medical Sciences and Technology 1, Nr. 2 (2016): 42–46. http://dx.doi.org/10.5005/jp-journals-10057-0011.
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ABSTRACT Background As the number of drugs available in the market are increasing, there arises a need to detect their adverse drug reactions and report them on time so that further harm can be avoided. The level of underreporting of adverse drug reactions is very high. Therefore, present study aimed to assess the knowledge, attitude and practice (KAP) of pharmacovigilance among the various health care professionals and suggest ways to improve them. Materials and methods A cross-sectional survey was done on 215 health care personnels working in a medical college in Jaipur. They were subjected to KAP questionnaire consisted of knowledge, attitude and practice based questions, designed specifically to assess the awareness about pharmacovigilance. Results and conclusion The mean KAP scores of physicians were found to be 5.75, 4.44 and 1.75 respectively. The KAP score of postgraduate students was 5.5, 4.25 and 1.5 respectively. The KAP score of final year MBBS students was 5, 3.4, and 1.4 respectively, and that of interns was 4, 4.2 and 1.4 respectively. The KAP score of pharmacists was 3.5, 2 and 1 respectively, and that of nurses was 2.75, 2.25 and 0.8 respectively. It was found that mean score of physicians and postgraduate students was higher than interns and final year MBBS and much higher than nurses and pharmacists. Still they all fall under the poor score range to unsatisfactory score range which suggest that there is an urgent need for ongoing educational programs to train health care professionals about pharmacovigilance. How to cite this article Vohra A, Vohra R, Verma M. Poor Knowledge, Attitude and Practices of Pharmacovigilance among Health Care Professionals: A Cross-sectional Study. J Mahatma Gandhi Univ Med Sci Tech 2016;1(2):42-46.
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Jedel, P. E., und D. F. Salmon. „Yield and grain quality of plump-kernelled spring triticale windrowed at different kernel water concentrations“. Canadian Journal of Plant Science 77, Nr. 4 (01.10.1997): 561–66. http://dx.doi.org/10.4141/p97-007.
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Little information is available on the response of plump-kernelled spring triticales (X Triticosecale Wittmack) to windrowing at different kernel water concentrations (KWC). The objective of this research was to determine the effects of windrowing at KWCs of 1600 g kg−1 or less on the yield and grain quality of spring triticales compared with a Canadian prairie spring (CPS) wheat (Triticum aestivum L. 'Oslo'). Field experiments were conducted from 1989 to 1993 at Lacombe, AB, using the spring triticale cv. Wapiti in all years, and the cvs. Banjo and Frank in 1992 and 1993. Rate of dry-down varied between the cultivars and years. Oslo dried at a rate of 1.67 to 3.23 g kg−1 per growing degree day (GDD 0 °C basis). The rate of dry-down for the triticales ranged from 2.80 to 10.80 g kg−1 per GDD. Although the triticales reached physiological maturity much later than Oslo in any given year, they dried at a faster rate (with fewer GDDs) than Oslo. Windrowing at KWC of up to 1600 g kg−1 (62% moisture) had no effect on test weight, grain protein or germination of harvested grain. Effects of windrowing on grain yield varied but, when yield differences were significant, windrowing at 430 to 530 g kg−1 (30 to 35% moisture) optimized grain yield. When effects of windrowing on kernel weight were significant, kernel weight increased as KWC at windrowing decreased. When windrowing to curtail secondary growth of spring triticale is necessary in central Alberta, windrowing at 430 to 530 g kg−1 (30 to 35% moisture) is recommended to optimize yield without loss of test weight, protein content or germination. Key words: Spring triticale, Canadian prairie spring wheat, windrowing, kernel water concentration
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French, J. Victor, und Santiago Villarreal. „Evaluation of Cm-006 for Citrus Red Mite Control, 1996“. Arthropod Management Tests 22, Nr. 1 (01.01.1997): 60–61. http://dx.doi.org/10.1093/amt/22.1.60a.
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Abstract Experimental CM-006, alone and tank-mixed with NR 435 Oil or Kinetic adjuvant, were compared with Agri-Mek + NR 435 Oil for efficacy against RdM on nursery citrus. Treatments were randomized and each replicated on 4 potted grapefruit trees (each ca. 2 ft high). Sprays were applied to foliar run-off using a TQ-40 Koke Kap CO2 handgun sprayer nozzled with a 8002 Tee-Jet tip and pressure set at 30 psi. At each count date 3 leaves per replicate tree (12/treatment) were randomly sampled and processed in the laboratory through a Leedom Mite Brushing Machine. RdM from each replicate were collected on a detergent-coated glass disc and counted under a binocular microscope at 20X.
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Balegha, Augustine Ngmenemandel, Adadow Yidana und Gilbert Abotisem Abiiro. „Knowledge, attitude and practice of hepatitis B infection prevention among nursing students in the Upper West Region of Ghana: A cross-sectional study“. PLOS ONE 16, Nr. 10 (14.10.2021): e0258757. http://dx.doi.org/10.1371/journal.pone.0258757.
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Introduction Hepatitis B infection remains a public health threat associated with undesirable statistics of morbidity and mortality. Good knowledge, attitude and practice (KAP) of hepatitis B infection (HBI) prevention are essential for HBI control. However, there is limited evidence concerning the KAP of HBI prevention among nursing students, who are significantly exposed to HBI. We assessed the KAP of HBI prevention and the factors associated with the practice of HBI prevention among nursing students in the Upper West Region of Ghana. Methods We administered an online cross-sectional survey in November 2020 to a stratified random sample of 402 nursing students in two nursing training colleges in the Upper West Region. Using STATA version 13, we computed composite scores of KAP of HBI prevention with maximum scores of 18 for knowledge and 8 each for attitude and practice. A generalised ordered logistic regression model was run to assess the factors associated with the practice of HBI prevention. Results The students had moderate median scores for knowledge (12.00; IQR = 10–13) and attitude (6.00; IQR = 5.00–7.00) but a poor median score (5.00; IQR = 4.00–6.00) for the practice of HBI prevention. High knowledge (aOR = 2.05; p = 0.06), good attitude, being a male, second year student and having parents with tertiary education were significantly associated with higher likelihoods (aOR >1; p < 0.05) of demonstrating good practice of HBI prevention. Students who had never married were significantly (aOR = 0.34; p = 0.010) less likely to exhibit good practice of HBI prevention. Conclusion The KAP scores of HBI prevention among the students were sub-optimal. We recommend institution-based policies and regular education on HBI prevention, free/subsidised HBI prevention services, and the enforcement of proper professional ethics on HBI prevention in nursing training colleges. Such interventions should predominantly target female, non-married and first year nursing students.
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Balegha, Augustine Ngmenemandel, Adadow Yidana und Gilbert Abotisem Abiiro. „Knowledge, attitude and practice of hepatitis B infection prevention among nursing students in the Upper West Region of Ghana: A cross-sectional study“. PLOS ONE 16, Nr. 10 (14.10.2021): e0258757. http://dx.doi.org/10.1371/journal.pone.0258757.
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Introduction Hepatitis B infection remains a public health threat associated with undesirable statistics of morbidity and mortality. Good knowledge, attitude and practice (KAP) of hepatitis B infection (HBI) prevention are essential for HBI control. However, there is limited evidence concerning the KAP of HBI prevention among nursing students, who are significantly exposed to HBI. We assessed the KAP of HBI prevention and the factors associated with the practice of HBI prevention among nursing students in the Upper West Region of Ghana. Methods We administered an online cross-sectional survey in November 2020 to a stratified random sample of 402 nursing students in two nursing training colleges in the Upper West Region. Using STATA version 13, we computed composite scores of KAP of HBI prevention with maximum scores of 18 for knowledge and 8 each for attitude and practice. A generalised ordered logistic regression model was run to assess the factors associated with the practice of HBI prevention. Results The students had moderate median scores for knowledge (12.00; IQR = 10–13) and attitude (6.00; IQR = 5.00–7.00) but a poor median score (5.00; IQR = 4.00–6.00) for the practice of HBI prevention. High knowledge (aOR = 2.05; p = 0.06), good attitude, being a male, second year student and having parents with tertiary education were significantly associated with higher likelihoods (aOR >1; p < 0.05) of demonstrating good practice of HBI prevention. Students who had never married were significantly (aOR = 0.34; p = 0.010) less likely to exhibit good practice of HBI prevention. Conclusion The KAP scores of HBI prevention among the students were sub-optimal. We recommend institution-based policies and regular education on HBI prevention, free/subsidised HBI prevention services, and the enforcement of proper professional ethics on HBI prevention in nursing training colleges. Such interventions should predominantly target female, non-married and first year nursing students.
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Tomori, Michael Olabode. „Knowledge, Attitude and Perception of Federal University of Technology Akure (FUTA), Ondo State Students toward Coronavirus Pandemic“. International Journal of Pharmaceutical Sciences and Medicine 7, Nr. 1 (30.01.2022): 24–58. http://dx.doi.org/10.47760/ijpsm.2022.v07i01.002.
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Coronavirus disease (COVID-19) has become a pandemic requiring unprecedented measures adopted to control its rapid spread. The knowledge, attitudes and perception (KAP) of the public play a major role in the prevention and control of infectious diseases. In this study, FUTA students’ KAP towards COVID-19 during the rapid rise period of the outbreak was investigated. A cross-sectional survey was conducted in FUTA in October 2021 via a self-designed questionnaire comprising 25 questions assessing KAP. Assessments on students’ attitudes and perception towards COVID-19 included questions on confidence and believe in winning the war against COVID-19 such as wearing face masks and use of hands sanitizer. Among the questionnaire completed (n=402), 58.0% were men while 42.0% were female, 17.7% were from school of Agriculture, and 20.1% were in 300 level. The overall adequate knowledge on the existence of the disease was 88.6%. The majority of the respondents displayed good attitude towards the spread of COVID-19 pandemic in FUTA as 79.6% of the students were in agreement with the rules of the Nigeria Center for Disease Control and Prevention (NCDC). In addition, the study showed that age factors cannot affect the perception of students to COVID-19 as the P-value (0.733) is greater than 0.05.
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Pakpahan, Elvira Fitriyani. „Reconstruction of Bonds Arrangements in Indonesian Capital Market Justice-Based Value“. International Journal of Law Reconstruction 1, Nr. 1 (21.08.2017): 36. http://dx.doi.org/10.26532/ijlr.v1i1.1638.
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Trustee contracts referring to the special provisions on guarantees stipulated by Bapepam (Capital Market Supervisory Agency)/OJK (Financial Service Authority) as referred in item 4 letter E Kep. Bapepam-LK No.412 / BL / 2010 are considered too general. The provision of guarantee on number 4 letter E Kep. Bapepam No.412 is limited to informational provisions, not a requirement. The purpose of this paper is to know and analyze the implementation of bond arrangements and weaknesses in the capital market of Indonesia based on the value of justice. Why there are weaknesses in the implementation of bond arrangement in Indonesia capital market. This research used sociological juridical method. The theories used to analyze were the theory of Degrading Justice as the Grand Theory, Theory of Legal Protection as the Middle Range Theory and Theory of the Covenant as Applied Theory. Based on the results of research implementation of bond arrangement in Indonesia capital market does not give justice value to the parties such as issuer, trustee and investor in particular. Unclear arrangements in Bapepam-LK's Decree on General Provisions and Trustee Contracts under the Warranty (if any) do not provide legal certainty and fairness to bond investors in the event of default. The weaknesses in the implementation of bonds arrangement in the Indonesian capital market due to the functions and duties of the Trustee listed in UUPM have no regulatory arrangements, as well as the absence of guidelines/standards in the preparation of the trustee contract. The reconstruction of the law shall be conducted by changing the special provisions of Bapepam Decree Number 412 on item 4 letter E concerning the guarantee (if any) by removing / removing the existing word in parentheses (if any), as it does not reflect the value of legal certainty and dignified justice.
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Shacham, S., M. Kauffman, V. Sandanayaka, G. Draetta, S. Shechter, J. Williams und R. Nir. „Preclinical development of small-molecule CRM1 inhibitors as novel therapy for the treatment of colorectal cancer (CRC).“ Journal of Clinical Oncology 29, Nr. 4_suppl (01.02.2011): 430. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.430.
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430 Background: CRM1 (XPO1) is a key nuclear export protein which controls the location of multiple tumor suppressor (TSP) and growth regulatory (GRP) proteins including p53, PI3K/AKT, Wnt/ß-catenin and NF-kB. Forced nuclear expression of TSP and GRP by CRM1 inhibition can lead to apoptosis in cancer cells while sparing normal cells. Methods: Novel small-moleculeCRM1 inhibitors were synthesized and nuclear distribution studies were performed in cells transfected with HIV-rev GFP proteins. Cell proliferation studies were performed in 16 CRC cell lines: LS-123, SW-626, Colo-201, Colo-205, Colo-320DM, Colo-320HSR, Lovo, DLD-1, HCT-15, WiDi, LS-174T, LS-180, SW-620, C2BBe1, HCT-8, HCT-116, and in human peripheral leukocytes (PBMC). Cellular distribution and apoptosis assays were performed on HCT-116. Antitumor activity is assessed in human HCT-116 xenografts in scid-mice. Results: The lead CRM1 inhibitor, KPT-0127, blocks CRM1 mediated nuclear export of HIV-Rev-GFP, FOXO, and p53 with an IC50 of ∼300 nM. KPT-0127 is cytotoxic to various CRC cell lines with EC50s of 0.07-1.1 μM; in 9 CRC lines EC50s were < 0.3 mM. In contrast, normal cell lines and PBMCs had EC50 > 5-20 μM. In HCT- 116 cells, KPT-0127 induces cell cycle arrest at both G1/S and G2/M checkpoints and dose dependently increases nuclear p53, followed by an increase in caspase 3. KTP-0127 10μM shows no significant effect on 37 proteins including several cysteine proteases. In mice, KPT-0127 given by SC injection of 30-100 mg/kg leads to serum levels exceeding the effective CRM1 inhibitory concentration for at least 4 hours and is well tolerated. KPT-0127 given SC to mice bearing HCT-116 colon xenografts results in dose-dependent antitumor activity. Conclusions: The novel small- molecule CRM1 inhibitor KTP-0127 kills CRC lines with multiple TSP, GRP, and oncogenic abnormalities, including p53 mutations/deletions and PTEN deficiency/AKT activation, while sparing normal cells. This likely reflects the ability of CRM1 inhibition to affect multiple critical and non-redundant regulatory pathways. These results support the development of CRM1 inhibitors for the treatment of CRC. IND-enabling CMC and toxicology work are in preparation. [Table: see text]
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Pasman, Yfke, Surrinder Saini, Elspeth Smith und Azad Kaushik. „Organization of bovine lambda light chain genes on chromosome 17 (43.14)“. Journal of Immunology 184, Nr. 1_Supplement (01.04.2010): 43.14. http://dx.doi.org/10.4049/jimmunol.184.supp.43.14.
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Abstract Twenty five Vλ genes, seventeen being functional Vλ, corresponding to the three Vλ gene families were identified upon complete characterization and physical mapping of bovine λ-light chain locus on chromosome 17. The bovine λ-light chain locus spans 412 kbp where the Vλgenes are located 23.7 kbp 5’ of four Jλ-Cλ units. The Vλgenes are organized in three subclusters separated by two large introns (126.8 and 138.3 kbp). The predominantly expressed Vλ1 genes are present in the two 5’ sub-clusters, while most Jλ-proximal Vλ sub-cluster comprises rarely expressed Vλ2 and Vλ3 genes. The Jλ3-Cλ3 unit was found predominantly expressed, though Jλ2 and Jλ3 have identical recombination signal sequences (RSS). The Cλ1 and Cλ4 are pseudogenes and their Jλ-Cλ units are not expressed. Endogenous counter selection for Jλ2 encoded CDR3 and framework 4 regions are likely the cause for the predominant expression of Jλ3-Cλ3 genes over Jλ2-Cλ2. The preferential expression of Vλ1 genes in the bovine Immunoglobulin repertoire seems to be influenced by the composition of RSSs. Polymorphism at the λ-light chain locus is responsible for differences in the genomic complexity between Hereford and Holstein cattle. Despite more potential germline encoded combinatorial diversity, the λ-light chain repertoire in cattle is predominantly encoded by Vλ1- Jλ3-Cλ3 recombinations. (Supported by NSERC Canada)
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Svensson, Anders, Daniel Thor, Michael A. Fischer und Torkel Brismar. „Dual source abdominal computed tomography: the effect of reduced X-ray tube voltage and intravenous contrast media dosage in patients with reduced renal function“. Acta Radiologica 60, Nr. 3 (22.06.2018): 293–300. http://dx.doi.org/10.1177/0284185118783213.
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Background X-ray tube voltage (kVp) reduction increases intravenous contrast medium (CM) attenuation at computed tomography (CT), but tube output limits its use in large patients. Purpose To evaluate the feasibility and image quality of reducing CM dose by low kVp and using dual X-ray source at liver CT. Material and Methods Patients with estimated glomerular filtration rate (eGFR) < 45 mL/min (n = 43) aged 60–91 years (75 ± 7.7), weighing 42–114 kg (75 ± 15) were prospectively scanned using a reduced CM dose of 0.25 or 0.3 g iodine (I)/kg with 70 or 80 kVp respectively, using either single-source or dual-source CT depending on patient size. Liver contrast-to-noise ratio (CNR), liver noise, and muscle noise were quantitatively compared with those of 43 consecutive patients aged > 65 years with eGFR > 45 mL/min scanned using a standard abdominal protocol at 120 kVp after receiving 0.5 gI/kg. Results There was no statistically significant difference in CNR, liver noise, or muscle noise at reduced CM protocols compared to the standard protocol: CNR was 4.6 (95% CI = 4.2–5.0) vs. 5.0 (95% CI = 4.5–5.5), liver noise was 11.1 (95% CI = 10.7–11.6) vs. 11.0 (95% CI = 10.5–11.6), muscle noise was 11.7 (95% CI = 11.2–12.1) vs. 10.8 (95% CI = 10.1–11.4). The mean SSDE was 70% higher with the reduced CM protocol. Conclusion CM dosage can be reduced by 40–50% with maintained measured noise and CNR in patients with BMIs of 15–36 kg/m2 by lowering the tube voltage and dual-source CT scanning of the liver.
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Ueno, K., Y. Uchino, K. Iizumi, K. Saiki und A. Koma. „Electron-energy-loss spectroscopy of KxC60 and K-halides: comparison in the K3p excitation region“. Applied Surface Science 169-170 (Januar 2001): 184–87. http://dx.doi.org/10.1016/s0169-4332(00)00729-7.
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Alexander, Susan I., Timothy S. Nwafor, Pam V. Gyang, Emmanuel T. Idowu und Olaoluwa P. Akinwale. „Prevalence of Urogenital Schistosomiasis and its Implication on Control Efforts Among School Pupils in Ogun State, Southwest Nigeria“. Pan African Journal of Life sciences 5, Nr. 3 (25.12.2021): 335–41. http://dx.doi.org/10.36108/pajols/1202.50.0350.
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Background: Schistosomiasis causes anaemia, stunting, and cognitive impairment in children, which impairs school performance. Government coordinated school-based preventive chemotherapy with donated praziquantel has been primarily used for schistosomiasis control in Ogun State, necessitating the need to monitor treatment coverage and its effect on schistosomiasis burden. Methods: We screened 422 pupils aged 1-14 years old for Schistosoma haematobium in June 2018 using the filtration technique. KAP data and socio-demographic characteristics of participants were also recorded. Results: Out of 422 screened pupils, 59 (14%) tested positive using the filtration method. Peak prevalence (31.6%) occurred in pupils under five years. Heavy infection intensity occurred in 3.4% of the infected population. KAP studies revealed that 55% knew schistosomiasis was linked to urinating blood. Symptoms experienced main-ly were diarrhoea (44.6%), stomach ache (29.7 %), and fever (13.5 %). Pipe-borne water (48.2%), well water (28.7%), and stream water (23.1%) were the major sources of water for household chores. Investigations on excreta disposal showed that 70.3% defecated in latrines, 17.3% in the bush, and 12.4% in water closets. About 54.7% had contact with a stream, while 74.2% were dewormed in the last six months. Conclusion: Children below five years old should be included in the Ogun State’s Ministry of Health’s treatment efforts. Health education should be intensified in the study areas because the population visiting streams and openly defaecating will continue undermining the Ogun State Ministry of Health’s treatment efforts. Our study will serve as an evidence base for refining control measures and effectively utilising already scarce resources.
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Trisulo, Trisulo, und Iin Indrawati. „PEMBELAJARAN KOOPERATIF PENGISIAN E-FILING BAGI PELAKU UMKM DI KELURAHAN CIPADU-CILEDUG-TANGERANG“. Jurnal Pemberdayaan Masyarakat Indonesia 1, Nr. 2 (15.11.2019): 425–30. http://dx.doi.org/10.21632/jpmi.1.2.425-430.
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Direktorat Jenderal Pajak (DJP) mengembangkanberbagai aplikasi untuk mempermudah Wajib Pajak dalam melaksanakan kewajiban perpajakan melalui e-filing. Masih banyak Wajib Pajak yang belum memahami e-filingsehingga datang ke KPP untuk melaporkan SPT. Padahal dengan memanfaatkan e-filing, akan dapat lebih produktif waktu dan biaya. UMKM merupakan potensi baru dalam peningkatan kontribusi pajak. Pemerintah melalui beberapa regulasi membidik upaya peningkatan perpajakan dari sektor UMKM. Dianataya adalah penurunan tarif pajak UMKM dari 1% menjadi 0,5%. Masalah pemahaman dan kesadaran wajib pajak menjadi kunci keberhasilan upaya tersebut. Perlu dilakukan strategi khusus untuk mengedukasi masyarakat UMKM. Ini adalah bentuk tanggungjawab timbal balik antara rakyat dan pemerintah. Beberapa kendala dalam sosialisasi perpajakan diantaranya pengisian e-filing untuk keperluan pelaporan pajak. Ditemukan kesulitan di lapangan dalam memberikan materi sosialisasi pada UMKM terkait kewajiban perpajakan. Pembelajaran Kooperatif tipe Jigsaw dalam pengisisan e-filing, menjadi upaya untuk meningkatkan potensi perpajakan sektor UMKM, disamping sebagai bukti tanggungjawab pemerintah dalam pelayanan publik.
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Jha, S. K., Pallavi Singhal und R. M. Tripathi. „Evaluation of enviornmental increment values for radionuclides monitoring around proposed uranium mines at K.P. Mawthabah (Domiasiat) in Meghalaya“. Journal of Radioanalytical and Nuclear Chemistry 307, Nr. 2 (23.07.2015): 1545–50. http://dx.doi.org/10.1007/s10967-015-4325-9.
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Díaz-Bello, Dácil, Carlos Vargas-Salgado, Jesus Águila-León und Fabián Lara-Vargas. „Methodology to Estimate the Impact of the DC to AC Power Ratio, Azimuth, and Slope on Clipping Losses of Solar Photovoltaic Inverters: Application to a PV System Located in Valencia Spain“. Sustainability 15, Nr. 3 (03.02.2023): 2797. http://dx.doi.org/10.3390/su15032797.
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Renewable power capacity sets records annually, driven by solar photovoltaic power, which accounts for more than half of all renewable power expansion in 2021. In this sense, photovoltaic system design must be correctly defined before system installation to generate the maximum quantity of energy at the lowest possible cost. The proposed study analyses the oversizing of the solar array vs. the capacity of the solar inverter, seeking low clipping losses in the inverter. A real 4.2 kWp residential PV installation was modelled and validated using the software SAM and input data from different sources, such as a weather station for weather conditions, ESIOS for electricity rates, and FusionSolar to obtain energy data from the PV installation. Once data were validated through SAM, the DC to AC ratio was varied between 0.9 and 2.1. The azimuth and slope sensitivity analyses were performed regarding clipping inverter losses. Results have been evaluated through the energy generated and the discounted payback period, showing that, depending on the weather conditions, slope, and azimuth, among others, it is advisable to increase the DC to AC ratio to values between 1.63 and 1.87, implying low discounted payback periods of about 8 to 9 years. In addition, it was observed that inverter clipping losses significantly vary depending on the defined azimuth and slope.
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Sami, Sahar, Faris Lami, Hiba Abdulrahman Rashak, Mohannad Al Nsour, Alaa Eid, Yousef Khader, Salma Afifi Sr et al. „Public Health Workers’ Knowledge, Attitude, and Practice Regarding COVID-19: The Impact of the Field Epidemiology Training Program in the Eastern Mediterranean Region“. Iproceedings 8, Nr. 1 (04.02.2022): e36491. http://dx.doi.org/10.2196/36491.
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Background Globally, there is a growing need for public health professionals skilled in preventing and responding to the surge of emerging and re-emerging infectious diseases. This is particularly important to the Eastern Mediterranean countries that are facing emergencies in addition to the increased public health risks of unprecedented scale during the COVID-19 pandemic. Public health professionals are instrumental in responding to the COVID-19 pandemic in terms of detecting and monitoring new cases, conducting investigations, tracing contacts, ensuring patients are being tested, applying isolation and quarantine protocols, providing up-to-date information, educating the community, and producing statistics and models to track disease progression. Objective This study aims to compare knowledge, attitude, and practice (KAP) regarding COVID-19 between public health workers (PHWs) that attended the Field Epidemiology Training Program (FETP trained) and those who did not attend FETP (non-FETP trained). Methods A multicountry cross-sectional survey was conducted among PHWs who participated in the COVID-19 pandemic in 10 countries in the Eastern Mediterranean Region. An online questionnaire that included demographic information and KAP regarding the COVID-19 pandemic was distributed among PHWs. The scoring system was used to quantify the answers; bivariate and multivariate analyses were performed to compare FETP-trained with non-FETP–trained PHWs. Results Overall, 1337 PHWs participated, with 835 (62.4%) <40 years of age and 851 (63.6%) male participants. Of them, 423 (31.6%) were FETP trained, including 189 (44.7%) at an advanced level, 155 (36.6%) at an intermediate level, and 79 (18.7%) had basic level training. Compared to non-FETP–trained participants, FETP-trained participants were older and had higher KAP scores. FETP participation was low in infection control and public health laboratories. KAP mean scores for intermediate-level attendees were comparable to the advanced level. Conclusions FETP-trained participants had better KAP than non-FETP–trained PHWs. Expanding the intermediate level, maintaining the rapid response training, and introducing the laboratory component are recommended to maximize the benefit from the FETP. Infection control, antimicrobial resistance, and coordination are areas where training should be included.
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Badgujar, Jatin V., Gaurav M. Sharma, Nisha R. Relwani, Omprakash S. Rohondia, Tanvi D. Patole und Anjali S. Puntambekar. „Knowledge, attitude and practices regarding the use of personal protective equipment during COVID-19 pandemic among health care workers at a tertiary health care center“. International Journal Of Community Medicine And Public Health 8, Nr. 5 (27.04.2021): 2321. http://dx.doi.org/10.18203/2394-6040.ijcmph20211753.
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Background: The aim of the present study was to assess the knowledge, attitude and practices (KAP) regarding the use of personal protective equipment (PPE) during COVID-19 pandemic among health care workers.Methods: A cross-sectional study was conducted among health care workers (HCW) including junior and senior resident doctors and nursing staff working at a tertiary health care center. A pre-designed, pre-validated, semi-structured questionnaire regarding the use of PPE was distributed online to eligible HCW and their responses were recorded electronically between 14 April 2020 and 20 April 2020. The survey questionnaire consisted of questions based on demographic and background characteristics along with KAP; knowledge (K1-K6), attitude (A1-A3) and practices (P1-P4).Results: A total of 423 out of 475 eligible participants successfully submitted their responses and were included in the present study which included junior resident doctors (55.70%), senior resident doctors (19.60%) and nursing staff (24.60%). The mean total knowledge score was 4.169±1.006 with an overall correct response rate of 75.8%. The result of one way ANOVA indicated that there is significant difference in the mean total knowledge score according to designation (F=6602, p<01) with improved knowledge score seen in HCW with higher designation. Majority of HCW had positive attitude and appropriate practices regarding the use of PPE.Conclusions: Optimal use of PPE is crucial to avoid transmission of infection in health care setting. Assessment of KAP of HCW regarding the use of PPE can help hospital authorities to introduce educational programs accordingly to gaps identified in the survey.
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Alrazeeni, Daifallah. „Knowledge, attitude, and practice toward COVID-19 among paramedics in Saudi Arabia: Implications for educational program“. International Journal of ADVANCED AND APPLIED SCIENCES 8, Nr. 3 (März 2021): 71–77. http://dx.doi.org/10.21833/ijaas.2021.03.010.
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Coronavirus disease-2019 (COVID-19) is an ongoing public health issue, which threatens the lives of more than 2.4 million people worldwide. This study's purpose is to establish paramedics’ knowledge, attitude, and practices (KAP) towards COVID-19 in Saudi Arabia. An online cross-sectional, descriptive study was conducted among paramedics in four hospitals via WhatsApp Messenger. The study population was composed of paramedics aged 18 years and above. A pre-validated questionnaire was used to evaluate KAP towards COVID-19. Bloom’s cut-off of 80% was used to assess sufficient knowledge (≥80%), positive attitude (≥4), and good practice (≥2.4). All analyses were performed using SPSS version 26 of the approaching 300 paramedics, 71 (24%) responded. The majority of participants were male (n=61, n=85.9%), with an average age of 33 (range: 18–57) years. Overall, 4.2% (n=3) had sufficient knowledge, 42% (n=30) had a positive attitude, and 4% (n=4) had good practice regarding to COVID-19. There was a statistically significant difference between paramedics’ KAP according to their socio-demographic characteristics. Younger paramedics (≥ 18) have sufficient knowledge and a good practice toward COVID-19 than older paramedics (≥37) (p=0.000, p=0.005), respectively. Older paramedics (≥37) have a positive attitude towards COVID-19 relative to younger paramedics (≥ 18) (p=0.000). A statistically significant difference between the total KAP and the level of education (p=0.000) at which the diploma (p=0.000) had sufficient knowledge of COVID-19 than the bachelors and the postgraduate level. Bachelor's and graduates have a positive attitude (p=0.000) towards COVID-19 than the diploma. Saudi paramedics have poor knowledge of COVID-19. In addition, the results of this study have shown that there are statistically significant differences in KAPs’ paramedics according to their demographic characteristics. The author suggests follow-up studies concerning emergency medical services (EMS) settings around the country. Relevance to clinical practice: Ongoing professional education program for Saudi paramedics is encouraged to improve knowledge of paramedics, thus preventing negative attitudes and encouraging constructive preventive and therapeutic practices.
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Alrazeeni, Daifallah. „Knowledge, attitude, and practice toward COVID-19 among paramedics in Saudi Arabia: Implications for educational program“. International Journal of ADVANCED AND APPLIED SCIENCES 8, Nr. 3 (März 2021): 71–77. http://dx.doi.org/10.21833/ijaas.2021.03.010.
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Coronavirus disease-2019 (COVID-19) is an ongoing public health issue, which threatens the lives of more than 2.4 million people worldwide. This study's purpose is to establish paramedics’ knowledge, attitude, and practices (KAP) towards COVID-19 in Saudi Arabia. An online cross-sectional, descriptive study was conducted among paramedics in four hospitals via WhatsApp Messenger. The study population was composed of paramedics aged 18 years and above. A pre-validated questionnaire was used to evaluate KAP towards COVID-19. Bloom’s cut-off of 80% was used to assess sufficient knowledge (≥80%), positive attitude (≥4), and good practice (≥2.4). All analyses were performed using SPSS version 26 of the approaching 300 paramedics, 71 (24%) responded. The majority of participants were male (n=61, n=85.9%), with an average age of 33 (range: 18–57) years. Overall, 4.2% (n=3) had sufficient knowledge, 42% (n=30) had a positive attitude, and 4% (n=4) had good practice regarding to COVID-19. There was a statistically significant difference between paramedics’ KAP according to their socio-demographic characteristics. Younger paramedics (≥ 18) have sufficient knowledge and a good practice toward COVID-19 than older paramedics (≥37) (p=0.000, p=0.005), respectively. Older paramedics (≥37) have a positive attitude towards COVID-19 relative to younger paramedics (≥ 18) (p=0.000). A statistically significant difference between the total KAP and the level of education (p=0.000) at which the diploma (p=0.000) had sufficient knowledge of COVID-19 than the bachelors and the postgraduate level. Bachelor's and graduates have a positive attitude (p=0.000) towards COVID-19 than the diploma. Saudi paramedics have poor knowledge of COVID-19. In addition, the results of this study have shown that there are statistically significant differences in KAPs’ paramedics according to their demographic characteristics. The author suggests follow-up studies concerning emergency medical services (EMS) settings around the country. Relevance to clinical practice: Ongoing professional education program for Saudi paramedics is encouraged to improve knowledge of paramedics, thus preventing negative attitudes and encouraging constructive preventive and therapeutic practices.
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Chandra, Sunita, Sheela V. Mane, Parag Biniwale, M. Tripura Sundari, Anuradha Mulye und Charles Adhav. „Micronutrient supplementation in pregnancy: a KAP survey with healthcare consultants in India“. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, Nr. 2 (25.01.2023): 420–26. http://dx.doi.org/10.18203/2320-1770.ijrcog20230127.
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Background: Maternal nutrition during pregnancy is a serious public health issue as it negatively impacts women and their children. The most commonly used nutritional interventions during pregnancy are folic acid and omega-3 fatty acid (n-3 FA). This survey aimed to evaluate the knowledge, attitude and perception towards folic acid, n-3 FA and other supplementation amongst healthcare practitioners (HCPs). Methods: A close-ended questionnaire-based survey was distributed among obstetricians-gynaecologists and HCPs overlooking pregnant and lactating women between July and September 2022 in India. An excel based survey analysis was performed once the survey completed. Results: A total of 500 valid questionnaires were collected. Only 55% of them recommended n-3 FA, whereas 45% did not recommend as they believed that the typical Indian diet provides enough n-3 FA and supplements are not necessary. The majority (58.91%) of prescribers prescribed n-3 FA to all pregnant women, followed by older women with a history of abortion and high-risk pregnancy. Both eicosapentaenoic acid and docosahexaenoic acid were favoured in clinical practice. In addition, 56.8% of HCPs recommended folic acid at a dose of 5 mg/day for patients with a bad obstetric history, while 43.2% of HCPs recommended folic acid at a dose of 1 mg/day. Conclusions: Supplements and adequate nutrition can reduce the likelihood of poor maternal and foetal outcomes in high-risk pregnancies. Nutritional supplementation is a cost-effective and safe risk-reduction method, given the high prevalence of pregnancy complications. However, more knowledge dissemination on n-3 FA supplements, folic acid and micronutrients is essential.
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Punt, Maarten, Sjoerd J. Seekles, Jisca L. van Dam, Connor de Adelhart Toorop, Raithel R. Martina, Jos Houbraken, Arthur F. J. Ram, Han A. B. Wösten und Robin A. Ohm. „High sorbic acid resistance of Penicillium roqueforti is mediated by the SORBUS gene cluster“. PLOS Genetics 18, Nr. 6 (15.06.2022): e1010086. http://dx.doi.org/10.1371/journal.pgen.1010086.
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Penicillium roqueforti is a major food-spoilage fungus known for its high resistance to the food preservative sorbic acid. Here, we demonstrate that the minimum inhibitory concentration of undissociated sorbic acid (MICu) ranges between 4.2 and 21.2 mM when 34 P. roqueforti strains were grown on malt extract broth. A genome-wide association study revealed that the six most resistant strains contained the 180 kbp gene cluster SORBUS, which was absent in the other 28 strains. In addition, a SNP analysis revealed five genes outside the SORBUS cluster that may be linked to sorbic acid resistance. A partial SORBUS knock-out (>100 of 180 kbp) in a resistant strain reduced sorbic acid resistance to similar levels as observed in the sensitive strains. Whole genome transcriptome analysis revealed a small set of genes present in both resistant and sensitive P. roqueforti strains that were differentially expressed in the presence of the weak acid. These genes could explain why P. roqueforti is more resistant to sorbic acid when compared to other fungi, even in the absence of the SORBUS cluster. Together, the MICu of 21.2 mM makes P. roqueforti among the most sorbic acid-resistant fungi, if not the most resistant fungus, which is mediated by the SORBUS gene cluster.
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Ongkudon, Clarence M., Raelene Pickering, Diane Webster und Michael K. Danquah. „Cultivation of E. coli carrying a plasmid-based Measles vaccine construct (4.2 kbp pcDNA3F) employing medium optimisation and pH-temperature induction techniques“. Microbial Cell Factories 10, Nr. 1 (2011): 16. http://dx.doi.org/10.1186/1475-2859-10-16.
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Astuti, Vera. „“BYSTANDER EFFECT” IN CASES OF CORRUPTION IN CORPORATE, BUREAUCRATIC AND POLITICAL ORDERS“. Jurnal Hukum dan Peradilan 8, Nr. 3 (12.12.2019): 420. http://dx.doi.org/10.25216/jhp.8.3.2019.420-438.
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E-KTP Corruption is an organized crime that occurs in Indonesia. The corruption that has been established is to form an organized network due to the phenomenon "baystander effect" where it is a phenomenon of social psychology due to the loss of a sense of virginity to act to do something on an incident that Characterized by the interdependent nature of each other which eventually nothing moves one. This research aims to prove the existence of a matter of silence because it is triggered by personal interests or "self-interest" of the persons involved until difficult to control by the State apparatus. This method of research refers to the reference of legislation, information submitted by the media, statements from politicians and bureaucracy officials, court decisions and also reference books. The results of the study showed that the corruption that ensnares the bureaucracy officials and the politicians in fact has also dragged corporations. Participating in the case of the persons in corruption cases of intertwining creates a crime that is organized in such a way to harm the country and cause millions of people to be injured in the sleep. When they feel benefited over this corruption case then they choose silence, this is the phenomenon called "baystander effect" thus complicating the investigation in dismantling this corruption case.
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Metaxas, Vasileios I., Gerasimos A. Messaris, Aristea N. Lekatou, Theodore G. Petsas und George S. Panayiotakis. „PATIENT DOSE IN DIGITAL RADIOGRAPHY UTILISING BMI CLASSIFICATION“. Radiation Protection Dosimetry 184, Nr. 2 (17.11.2018): 155–67. http://dx.doi.org/10.1093/rpd/ncy194.
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Abstract Dose audit is important towards optimisation of patients’ radiation protection in diagnostic radiography. In this study, the effect of the body mass index (BMI) on radiation dose received by 1869 adult patients undergoing chest, abdomen, lumbar spine, kidneys and urinary bladder (KUB) and pelvis radiography in an X-ray room with a digital radiography system was investigated. Patients were categorised into three groups (normal, overweight and obese) based on the BMI values. The patients’ entrance surface air kerma (ESAK) and the effective dose (ED) were calculated based on the X-ray tube output, exposure parameters and technical data, as well as utilising appropriate conversion coefficients of the recorded kerma area product (KAP) values. The local diagnostic reference levels (LDRLs) were established at the 75th percentile of the distribution of ESAK and KAP values. Statistically, a significant increase was found in ESAK, KAP and ED values, for all examinations, both for overweight and obese patients compared to normal patients (Mann–Whitney test, p < 0.0001). Regarding the gender of the patients, a statistically significant increase was found in the dose values for male patients compared to female patients, except for the chest LAT examinations (Mann–Whitney test, p = 0.06). The percentage increase for chest PA, chest LAT, abdomen AP, lumbar spine AP, lumbar spine LAT, pelvis AP and KUB AP in overweight patients was 75%, 100%, 136%, 130%, 70%, 66% and 174% for median ESAK, 67%, 81%, 135%, 134%, 85%, 63% and 172% for median KAP, as well as 89%, 54%, 146%, 138%, 82%, 57% and 183% for median ED values, respectively. For obese patients, the corresponding increases were 200%, 186%, 459%, 345%, 203%, 150% and 785% for median ESAK, 200%, 185%, 423%, 357%, 227%, 142% and 597% for median KAP, as well as 222%, 156%, 446%, 363%, 218%, 136% and 625% for median ED. The corresponding LDRLs for overweight patients were 0.17 mGy, 1.21 mGy, 3.74 mGy, 7.70 mGy, 7.99 mGy, 4.07mGy, 5.03 mGy and 0.13 Gy cm2, 0.69 Gy cm2, 2.35 Gy cm2, 2.10 Gy cm2, 2.59 Gy cm2, 2.13 Gy cm2, 2.49 Gy cm2 in terms of ESAK and KAP values, respectively, while in the case of obese patients were 0.28 mGy, 1.82 mGy, 7.26 mGy, 15.10 mGy, 13.86 mGy, 6.89 mGy, 13.40 mGy and 0.21 Gy cm2, 1.10 Gy cm2, 4.68 Gy cm2, 4.01 Gy cm2, 4.80 Gy cm2, 3.27 Gy cm2, 6.02 Gy cm2, respectively. It can be concluded that overweight and obese patients received a significantly increased radiation dose. Careful adjustment of imaging protocols is needed for these patients to reduce patient dose, while keeping the image quality at an acceptable level. Additional studies need to be conducted for these patient groups, that could further contribute to the development of radiation protection culture in diagnostic radiography.
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Du, Yonghua, Yi Zhu, Shibo Xi, Ping Yang, Herbert O. Moser, Mark B. H. Breese und Armando Borgna. „XAFCA: a new XAFS beamline for catalysis research“. Journal of Synchrotron Radiation 22, Nr. 3 (09.04.2015): 839–43. http://dx.doi.org/10.1107/s1600577515002854.
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A new X-ray absorption fine-structure (XAFS) spectroscopy beamline for fundamental and applied catalysis research, called XAFCA, has been built by the Institute of Chemical and Engineering Sciences, and the Singapore Synchrotron Light Source. XAFCA covers the photon energy range from 1.2 to 12.8 keV, making use of two sets of monochromator crystals, an Si (111) crystal for the range from 2.1 to 12.8 keV and a KTiOPO4crystal [KTP (011)] for the range between 1.2 and 2.8 keV. Experiments can be carried out in the temperature range from 4.2 to 1000 K and pressures up to 30 bar for catalysis research. A safety system has been incorporated, allowing the use of flammable and toxic gases such as H2and CO.
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Ahmed, Hina, Aziza Ahmed und Muhammad Ahmed Saeed. „Knowledge, Attitude and Practices (KAP) Regarding the Prevention against COVID-19 Infection at the Outset of Outbreak in Pakistan Amongst Smart Phone Users“. BioMedica 36, Nr. 2S (24.06.2020): 281–87. http://dx.doi.org/10.51441/biomedica//biomedica/5-430.
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<p><strong>Background and Objective:</strong> At the outset of outbreak of Coronavirus disease-19 (COVID-19) infection in Pakistan, there had been a lot of confusion regarding the preventive measures in general public. The objective of current study was to determine the knowledge, attitude and practices regarding the home preventive measures against COVID-19 infection amongst smart phone users at the outset of outbreak in Pakistan. <strong>Methods:</strong> It was a cross-sectional online survey to determine the knowledge, attitude and practice amongst the smart phone users regarding the preventive measures against Corona infection. Total 388 questionnaires were submitted in one week in first week of April 2020. The data was collected through online questionnaire which were disseminated through WhatsApp groups. The completed questionnaires were compiled and analysed by using SPSS software version 21. Frequencies of responses were calculated. <strong>Results:</strong> A total of 196 (50.5%) participant were in the age category of 17–25 years with female predominance. Three hundred and 66 (94.3%) preferred washing hands with soap and water for 20 or more seconds, two thirds of the participants also agreed on the role of sanitizers. Only 159 (41%) knew what social distancing meant. Regarding the disinfection of eatable and non-eatable, almost half of the participants agreed to use soap and water. Considering the most effective disinfectant, 225 (43.8%) preferred Dettol. Surgical mask and N-95 masks were considered the effective ways to avoid droplet infections. Regarding the survival of the virus in different media, majority of the responses were completely ignorant. <strong>Conclusion: </strong>There are still gaps in knowledge, attitude and practices regarding prevention against Coronavirus infection at the outset of this out-break in Pakistan.</p>
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D'Hoostelaere, L. A., K. Huppi, B. Mock, C. Mallett und M. Potter. „The Ig kappa L chain allelic groups among the Ig kappa haplotypes and Ig kappa crossover populations suggest a gene order.“ Journal of Immunology 141, Nr. 2 (15.07.1988): 652–61. http://dx.doi.org/10.4049/jimmunol.141.2.652.
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Abstract The Ig kappa complex locus of inbred mice found on chromosome 6 contains one constant (C kappa), five joining (J kappa), and 100 to 300 variable (V kappa) exons and spans an estimated 500 to 2000 kbp of DNA. The V kappa exons are organized into groups of highly homologous coding regions (approximately 300 bp) separated by approximately 10 kbp of intervening sequence. A group contains from 1 to 30 or more exons (exon refers to uninterrupted coding region DNA which is capable of encoding all or part of V kappa gene) that can be detected with specific DNA probes in conjunction with restriction endonuclease fragments (REF) from genomic DNA. Thirteen DNA probes specific for different V kappa exon groups and one DNA probe specific for J kappa and C kappa exons were used in conjunction with 55 inbred strains in an attempt to detect RFLP that could be used to establish Ig kappa allelic groups and Ig kappa haplotypes. Each probe detected two to four different REF patterns (allelic groups) among the panel of inbred mice examined. Size estimates of the REF were made, and each probe detected 4.2 to 107.7 kbp of DNA, including faint REF, 675.6 to 723.6 kbp of DNA could be detected within a single haplotype. Based on these allelic groups, seven haplotypes were identified among the 55 inbred strains of mice. No subline differences were detected, and the distribution of allelic groups implied common ancestry among many of the inbred strains examined. The DNA probes were also used in conjunction with recombinant inbred, congenic strains and backcross populations of mice. By using the analysis of known Ig kappa r populations, and assuming a common ancestry among the inbred strains, a gene order was predicted: Centromere-Hd-(Ig kappa-V11, Ig kappa-V24, Ig kappa-V9-26)-(Ig kappa-V1, Ig kappa-V9)-(Ig kappa-V4, Ig kappa-V8, Ig kappa-V10, Ig kappa-V12, 13, Ig kappa-V19)-(Ig kappa-V28, Rn7s-6)-Ig kappa-V23-(Ig kappa-V21, Ig kappa-J, Ig kappa-C)-(Ly2, Ly3)-wa-1.
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Saha, Sajal K., Chris Barton, Shukla Promite und Danielle Mazza. „Knowledge, Perceptions and Practices of Community Pharmacists Towards Antimicrobial Stewardship: A Systematic Scoping Review“. Antibiotics 8, Nr. 4 (12.12.2019): 263. http://dx.doi.org/10.3390/antibiotics8040263.
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The scope of antimicrobial stewardship (AMS) surveys on community pharmacists (CPs) is uncertain. This study examines the breadth and quality of AMS survey tools measuring the stewardship knowledge, perceptions and practices (KPP) of CPs and analyse survey outcomes. Following PRISMA-ScR checklist and Arksey and O’Malley’s methodological framework seven medical databases were searched. Two reviewers independently screened the literatures, assessed quality of surveys and KPP outcomes were analysed and described. Ten surveys were identified that assessed CPs’ AMS perceptions (n = 7) and practices (n = 8) but none that assessed AMS knowledge. Three survey tools had been formally validated. Most CPs perceived that AMS improved patient care (median 86.0%, IQR, 83.3–93.5%, n = 6), and reduced inappropriate antibiotic use (84.0%, IQR, 83–85%, n = 2). CPs collaborated with prescribers for infection control (54.7%, IQR 34.8–63.2%, n = 4) and for uncertain antibiotic treatment (77.0%, IQR 55.2–77.8%, n = 5). CPs educated patients (53.0%, IQR, 43.2–67.4%, n = 5) and screened guideline-compliance of antimicrobial prescriptions (47.5%, IQR, 25.2–58.3%, n = 3). Guidelines, training, interactions with prescribers, and reimbursement models were major barriers to CP-led AMS implementation. A limited number of validated survey tools are available to assess AMS perceptions and practices of CPs. AMS survey tools require further development to assess stewardship knowledge, stewardship targets, and implementation by CPs.