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Zeitschriftenartikel zum Thema „914.445 95“

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Veröffentlicht am 18. Mai 2024

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1

Bowe, Benjamin, Yan Xie, Tingting Li, Yan Yan, Hong Xian, and Ziyad Al-Aly. "Estimates of the 2016 global burden of kidney disease attributable to ambient fine particulate matter air pollution." BMJ Open 9, no. 5 (2019): e022450. http://dx.doi.org/10.1136/bmjopen-2018-022450.

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ObjectiveTo quantitate the 2016 global and national burden of chronic kidney disease (CKD) attributable to ambient fine particulate matter air pollution ≤ 2.5 μm in aerodynamic diameter (PM2.5).DesignWe used the Global Burden of Disease (GBD) study data and methodologies to estimate the 2016 burden of CKD attributable to PM2.5in 194 countries and territories. Population-weighted PM2.5levels and incident rates of CKD for each country were curated from the GBD study publicly available data sources.SettingGBD global and national data on PM2.5and CKD.Participants194 countries and territories.Main

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Kotapati, Sravanthi, Insija Ilyas Selene, Madeeha Shafqat, et al. "Efficacy and Toxicity of Lenalidomide for Treatment of Chronic Lymphocytic Leukemia: A Systematic Review and Meta-Analysis." Blood 134, Supplement_1 (2019): 5488. http://dx.doi.org/10.1182/blood-2019-129733.

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Background: During last decade, several therapeutic options have emerged for newly diagnosed (ND) or relapsed / refractory (RR) patients with chronic lymphocytic leukemia (CLL). Lenalidomide (Lena) has immunomodulatory, anti-angiogenic and antitumor activity. Lena is showing antitumor activity against CLL with durable responses.The main aim of our analysis is to study the published literature on the efficacy and safety of Lena based regimens in patients with ND and RR CLL. Methods: We performed the literature search (10/5/2019) using following databases (PubMed, Embase, Cochrane Library, Web o

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Christensen, S. "Removal of haem from lipids extracted from intact erythrocytes with particular reference to polyphosphoinositides." Biochemical Journal 233, no. 3 (1986): 921–24. http://dx.doi.org/10.1042/bj2330921.

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With the use of a modified acid version of a current lipid-extraction technique [Bligh & Dyer (1959) Can. J. Biochem. Physiol. 37, 911-917], 92% of phosphatidylinositol 4,5-bisphosphate obtained by means of three sequential extractions from intact human erythrocytes was obtained during the first one. Some 95% of the haem co-extracted with the lipids could then be removed, with a maximal loss of polyphosphoinositides of less than 3%. About 58 nmol of phosphatidylinositol 4,5-bisphosphate was found per ml of erythrocytes.

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Bradbury, Charlotte A., Zoe Craig, Gordon Cook, et al. "Thrombosis in patients with myeloma treated in the Myeloma IX and Myeloma XI phase 3 randomized controlled trials." Blood 136, no. 9 (2020): 1091–104. http://dx.doi.org/10.1182/blood.2020005125.

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Abstract Newly diagnosed multiple myeloma (NDMM) patients treated with immunomodulatory drugs are at high risk of venous thromboembolism (VTE), but data are lacking from large prospective cohorts. We present thrombosis outcome data from Myeloma IX (n = 1936) and Myeloma XI (n = 4358) phase 3 randomized controlled trials for NDMM that treated transplant-eligible and transplant-ineligible patients before and after publication of thrombosis prevention guidelines. In Myeloma IX, transplant-eligible patients randomly assigned to cyclophosphamide, vincristine, doxorubicin, and dexamethasone (CVAD) i

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Mellish, Martha, Kasadee Allan, and Bronwyn Crane. "Effects of sunlight hours and hormones on double ovulation, and singleton and twin pregnancies in mares." Clinical Theriogenology 13, no. 2 (2021): 81–84. http://dx.doi.org/10.58292/ct.v13.9356.

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Equine twin pregnancies are almost exclusively dizygotic, without the application of advanced reproductive technologies, requiring 2ovulations in 1 estrous cycle. Breeding records were used to determine the effects of sunlight hours, prostaglandin F2α, human chorionicgonadotropin, deslorelin (a gonadotropin releasing hormone agonist), and progesterone and estradiol on double ovulation rates,and singleton and twin pregnancy rates. Breeding records of mares (n = 267) and their estrous cycles (n = 914) were analysed. Doubleovulations occurred in 10.5% (96/914) of estrous cycles. Twin pregnancies

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Tsuchiya, Norihiko, Yoshiaki Yamamoto, Hirotsugu Uemura, et al. "Avelumab (Ave) first-line (1L) maintenance plus best supportive care (BSC) versus BSC alone for advanced urothelial carcinoma (UC): JAVELIN Bladder 100 Japanese subgroup analysis." Journal of Clinical Oncology 39, no. 6_suppl (2021): 425. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.425.

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425 Background: A randomized phase III trial (JAVELIN Bladder 100; NCT02603432) to investigate avelumab (anti–PD-L1) as 1L maintenance therapy in patients with advanced UC met its primary objective, demonstrating significantly prolonged overall survival (OS) with Ave + BSC vs BSC alone in all randomized patients and in patients with PD-L1+ tumors. We report efficacy and safety in Japanese patients enrolled in this study. Methods: Eligible patients with unresectable locally advanced or metastatic UC that had not progressed with 4-6 cycles of gemcitabine with either cisplatin or carboplatin were

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Schulz, Victor C., Pedro S. C. de Magalhaes, Camila C. Carneiro, et al. "Improved Outcomes after Reperfusion Therapies for Ischemic Stroke: A “Real-world” Study in a Developing Country." Current Neurovascular Research 17, no. 4 (2020): 361–75. http://dx.doi.org/10.2174/1567202617666200521083132.

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Background: It is unknown if improvements in ischemic stroke (IS) outcomes reported after cerebral reperfusion therapies (CRT) in developed countries are also applicable to the “real world” scenario of low and middle-income countries. We aimed to measure the long-term outcomes of severe IS treated or not with CRT in Brazil. Methods: Patients from a stroke center of a state-run hospital were included. We compared the survival probability and functional status at 3 and 12 months in patients with severe IS treated or not with CRT. From 2010 to 2011, we performed intravenous reperfusion when patie

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Jin, Linda, Bradley Krasnick, Jesse Davidson, et al. "The effect of postoperative morbidity on long-term survival after curative resection for extra-hepatic biliary tumors: A multi-institution analysis from the U.S. Extrahepatic Biliary Malignancy Consortium." Journal of Clinical Oncology 34, no. 4_suppl (2016): 435. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.435.

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435 Background: Surgical resection is the cornerstone of curative therapy for extrahepatic biliary tumors (EHBTs) Postoperative complications (POCs) can negatively impact survival after oncologic resection. We evaluated the impact of POCs on survival after resection of EHBTs. Methods: We analyzed 914 patients from ten institutions of the U.S. Extrahepatic Biliary Malignancy Consortium who underwent curative resection for gallbladder adenocarcinoma (n=389), hilar (n=295) and distal (n=294) cholangiocarcinoma between 1998 and 2015. POCs were graded using the modified Clavien-Dindo system. Overal

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Patel, Kiran, Brenda Diergaarde, Adam Brufsky, et al. "Incidence of febrile neutropenia with use of docetaxel plus cyclophosphamide (TC) for breast cancer." Journal of Clinical Oncology 35, no. 15_suppl (2017): e12073-e12073. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e12073.

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e12073 Background: Incidence of febrile neutropenia (FN) is reported as 5% in breast cancer patients receiving TC (Jones et al., JCO 2006), which would not justify the usage of prophylactic granulocyte colony stimulating factors (G-CSF). We previously showed that the incidence of FN may be as high as 23% in a small study. (N = 130, Soni et al., ASCO 2011). In the current study, we determined the incidence of FN in a larger cohort (N = 415), and evaluated the usage of G-CSF and its relation to FN, age, stage, and hormonal status. Methods: We retrospectively reviewed the electronic medical recor

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Bando, H., T. Yoshino, E. Shinozaki, et al. "Clinical outcome in patients with metastatic colorectal cancer harboring KRAS p.G13D mutation treated with cetuximab." Journal of Clinical Oncology 29, no. 4_suppl (2011): 448. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.448.

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448 Background: Metastatic colorectal cancer patients with KRAS codon 12 or 13 mutated tumors are presently excluded from treatment with cetuximab (Cmab). On the other hand, a few patients who have mutated KRAS status occasionally respond to Cmab. The tumors of those patients predominantly had codon 13 mutation, and all codon 13 responder have mutation of p.G13D. We now compared the efficacy of Cmab among patients with p.G13D- mutant, other KRAS mutant and KRAS wild-type colorectal cancer. Methods: The patients from 9 Japanese institutions were retrospectively collected and analyzed. All patie

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Belozorov, Alexei, Olga Fedets, Tatjana Chastii, et al. "Chlamydia trachomatis infection positivity rates determined by nucleic acid amplification test in patients of hospitals in the northeastern region of Ukraine." International Journal of STD & AIDS 28, no. 14 (2017): 1405–9. http://dx.doi.org/10.1177/0956462417709831.

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There are no accurate data regarding the prevalence of Chlamydia trachomatis infection in Ukraine. This study aims to estimate the prevalence in the northeastern region of the country through reviewing nucleic acid amplification test results in patients of medical institutions in the Kharkov region during 2014–2016. Samples from 6920 patients (5028 women and 1892 men) aged 12–76 years were tested. The overall positivity rate was 4.5% (95% CI 4.0–5.0): 3.9% (95% CI 3.4–4.5) in women and 6.1% (95% CI 5.1–7.3) in men. The highest prevalence was found in the 16–20 (8.5%, CI 6.3–11.4) and 21–25 (8.

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Kukreja, Janet Baack, Roger Li, Mohamed Seif, et al. "A comparison of pathologic and intermediate term oncologic outcomes following open and robotic radical cystectomy." Journal of Clinical Oncology 37, no. 7_suppl (2019): 440. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.440.

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440 Background: Conflicting data regarding the oncologic efficacy of robotic surgery has led to concerns for possible inferiority. Despite recent prospective results from the RAZOR trial demonstrating non-inferior progression free survival, results from another prospective randomized trial from Memorial Sloan Kettering suggests a possible difference in the pattern of recurrences. We examined our experience with both open (ORC) and robotic radical cystectomy (RRC) with the objective of establishing recurrence patterns and pathologic comparisons at a high volume tertiary referral center. Methods

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Bender, Jacqueline L., Deb Feldman-Stewart, Christine Tong, et al. "Health-Related Internet Use Among Men With Prostate Cancer in Canada: Cancer Registry Survey Study." Journal of Medical Internet Research 21, no. 11 (2019): e14241. http://dx.doi.org/10.2196/14241.

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Background After a prostate cancer diagnosis, men want information about their disease and treatment options. The internet offers a convenient means to deliver health information to patients with prostate cancer. However, there are concerns about the use of the internet among this largely senior population. Objective This study aimed to determine the patterns and factors associated with the use of the internet as a source of health information among Canadian men with prostate cancer and the features and information required in a website. Methods Population surveys were conducted in four Canadi

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Elimian, Kelly Osezele, Olaolu Aderinola, Jack Gibson, et al. "Assessing the capacity of symptom scores to predict COVID-19 positivity in Nigeria: a national derivation and validation cohort study." BMJ Open 11, no. 9 (2021): e049699. http://dx.doi.org/10.1136/bmjopen-2021-049699.

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ObjectivesThis study aimed to develop and validate a symptom prediction tool for COVID-19 test positivity in Nigeria.DesignPredictive modelling study.SettingAll Nigeria States and the Federal Capital Territory.ParticipantsA cohort of 43 221 individuals within the national COVID-19 surveillance dataset from 27 February to 27 August 2020. Complete dataset was randomly split into two equal halves: derivation and validation datasets. Using the derivation dataset (n=21 477), backward multivariable logistic regression approach was used to identify symptoms positively associated with COVID-19 positiv

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Wissmann, Bárbara, Lucas Franzoni, César Augusto Miorelli Campos, et al. "Patients’ perception and use of medicinal plants for chronic disease in a community from Rio Grande do Sul / Percepção dos pacientes e uso de plantas medicinais para doenças crônicas em comunidade do Rio Grande do Sul." Brazilian Journal of Development 8, no. 5 (2022): 39589–608. http://dx.doi.org/10.34117/bjdv8n5-447.

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The popular use of medicinal plants to treat health problems is well known and disseminated from generation to generation, but little is known about toxicity and interactions. Therefore, this work aims to verify the perception about the use of medicinal plants for chronic patients in a community located in Rio Grande do Sul. A cross-sectional study was carried out with chronic diseases’ patients from the municipality of Novo Hamburgo, RS that are users of medicinal plants. Sociodemographic data, clinical characteristics and aspects related to the use of medicinal plants were evaluated for 100

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Ozguroglu, Mustafa, Ajjai Shivaram Alva, Tibor Csőszi, et al. "Analysis of PFS2 by subsequent therapy in KEYNOTE-361: Pembrolizumab (pembro) plus chemotherapy (chemo) or pembro alone versus chemo as 1L therapy for advanced urothelial carcinoma (UC)." Journal of Clinical Oncology 39, no. 6_suppl (2021): 448. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.448.

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448 Background: 1L pembro + chemo did not show statistically superior PFS and OS vs chemo for pts with advanced UC in the phase III KEYNOTE-361 study; OS for pembro vs chemo was not formally tested. We analyzed PFS2 (time from randomization to progressive disease [PD] on first subsequent therapy, or death from any cause, whichever occurs first) by study treatment and subsequent therapy in KEYNOTE-361 (NCT02853305) to determine the effects, if any, of therapy sequence on PFS2. Methods: PFS2 was estimated for pts in each treatment arm, who received any subsequent therapy including any anti–PD-(L

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Rey Lopez, Juan Pablo, Klaus Gebel, Debbie Chia, and Emmanuel Stamatakis. "Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults." BMJ Open Sport & Exercise Medicine 5, no. 1 (2019): e000596. http://dx.doi.org/10.1136/bmjsem-2019-000596.

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BackgroundPhysical activity recommendations state that for the same energy expenditure, moderate-to-vigorous physical activities (MVPAs) produce similar health benefits. However, few epidemiological studies have tested this hypothesis.DesignWe examined whether, compared with moderate, vigorous activity was associated with larger mortality risk reductions.MethodsData from 11 cohorts of the Health Survey for England and the Scottish Health Survey, collected from 1994 to 2011 (mean (SD) follow-up, 9.0 (3.6) years). Adults aged ≥30 years reported MVPA and linkage to mortality records. Exposure was

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Negrao, Marcelo V., Wen-Hsing Wu, Colin R. Lindsay, et al. "Abstract 918: Real-world clinical characteristics and treatment (tx) outcomes by co-mutation status in patients (pts) with KRAS G12C-mutated non-small cell lung cancer (NSCLC)." Cancer Research 83, no. 7_Supplement (2023): 918. http://dx.doi.org/10.1158/1538-7445.am2023-918.

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Abstract Background: KRAS mutations occur in ~30% of NSCLC and KRAS G12C is the most common subtype (~40%). Co-mutations can impact NSCLC prognosis and tx response. Methods: This retrospective study used the nationwide (US-based) de-identified Flatiron Health-Foundation Medicine clinico-genomic database (FH-FMI CGDB; January 1, 2011 to March 31, 2022). De-identified data originated from ~280 US cancer clinics (~800 sites of care). This study is based on tissue-based assay (FoundationOne CDx). Pts were aged ≥18 years; had KRAS G12C-mutated, advanced/metastatic NSCLC, and had received ≥1 line of

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Gafton, Georgiy, Valentin Anisimov, Dmitriy Matsko, Aleksandr Ivantsov, Ivan Gafton, and M. Myasnyankin. "LONG-TERM RESULTS OF TREATMENT OF PATIENTS WITH SUBUNGUAL MELANOMA." Problems in oncology 63, no. 3 (2017): 479–85. http://dx.doi.org/10.37469/0507-3758-2017-63-3-479-485.

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At the N.N. Petrov Research Institute of Oncology from 1986 to 2015 there were performed 445 radical operations for skin melanoma of upper and lower extremities in patients aged 18 to 87 years. The present study analyzed data of 40 patients with morphologically confirmed diagnosis of “subungual melanoma” (SM). Long-term results and causes of death were evaluated in all operated patients. A 1-year survival rate of SM patients, whatever stage of disease was 90%, a 5-year overall survival rate - 47%, while only 20% of patients have survived a 10-year line. Overall survival median was 55 ± 9.4 mon

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Martinez-Gomez, David, Irene Esteban-Cornejo, Esther Lopez-Garcia, et al. "Physical activity less than the recommended amount may prevent the onset of major biological risk factors for cardiovascular disease: a cohort study of 198 919 adults." British Journal of Sports Medicine 54, no. 4 (2018): 238–44. http://dx.doi.org/10.1136/bjsports-2018-099740.

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ObjectivesWe examined the dose–response relationship between physical activity (PA) and incidence of cardiovascular disease (CVD) risk factors in adults in Taiwan.MethodsThis study included 1 98 919 participants, aged 18–97 years, free of CVD, cancer and diabetes at baseline (1997–2013), who were followed until 2016. At baseline, participants were classified into five PA levels: inactive’ (0 metabolic equivalent of task (MET)-h/week), ‘lower insufficiently active’ (0.1–3.75 MET-h/week), ‘upper insufficiently active’ (3.75–7.49 MET-h/week), ‘active’ (7.5–14.99 MET-h/week) and ‘highly active’ (≥

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Cooper, Sue, Sarah Lewis, James G. Thornton, et al. "The SNAP trial: a randomised placebo-controlled trial of nicotine replacement therapy in pregnancy – clinical effectiveness and safety until 2 years after delivery, with economic evaluation." Health Technology Assessment 18, no. 54 (2014): 1–128. http://dx.doi.org/10.3310/hta18540.

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BackgroundSmoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would increase smoking cessation in pregnancy without adversely affecting infants.ObjectivesTo compare (1) at delivery, the clinical effectiveness and cost-effectiveness for achieving biochemically validated smoking cessation of NRT patches with placebo patches in pregnancy and (2) in infants at 2 years of age, the effects of maternal NRT patch use with plac

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Bruno Tongun, Mukunya, Tylleskar, Sebit, Tumwine, and Ndeezi. "Determinants of Health Facility Utilization at Birth in South Sudan." International Journal of Environmental Research and Public Health 16, no. 13 (2019): 2445. http://dx.doi.org/10.3390/ijerph16132445.

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South Sudan has a high maternal mortality ratio estimated at 800 deaths per 100,000 live births. Birth in health facilities with skilled attendants can lower this mortality. In this cross-sectional study, we determined the level and determinants of health facility utilization and skilled birth attendance in Jubek State, South Sudan. Mothers of children aged less than two years were interviewed in their homes. Multivariable regression analysis was performed to determine factors associated with health facility births. Only a quarter of the mothers had given birth at health facilities, 209/810 (2

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Kubanov, A. A., and E. V. Bogdanova. "Influence of age of onset of psoriasis on prevalence and clinical characteristics of psoriatic arthritis (according to the registry of patients with psoriasis)." Rheumatology Science and Practice 60, no. 4 (2022): 445–49. http://dx.doi.org/10.47360/1995-4484-2022-445-449.

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Сlinical, immunological and genetic differences between patients with early and late onset psoriasis are reported. Comparative studies of clinical characteristics of psoriatic arthritis according to age of psoriasis onset (skin manifestation) are lacking.Aim – to compare the prevalence and clinical characteristics of psoriatic arthritis depending on age of psoriasis onset (skin manifestation) in patients included to the psoriasis patient registry of Russian Society of Dermatovenereologists and Cosmetologists.Materials and methods. Prevalence of psoriatic arthritis in 3,227 patients with psoria

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Dakhel, Ardwan, Gunnar Engström, Olle Melander, et al. "Vasoactive Biomarkers Associated With Long-Term Incidence of Symptomatic Peripheral Arterial Disease and Mortality." Angiology 72, no. 6 (2021): 550–55. http://dx.doi.org/10.1177/0003319720987739.

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We evaluated if plasma biomarkers can predict incident peripheral arterial disease (PAD) and mortality in a longitudinal cohort study. Men (n = 3618) and women (n = 1542) were included in the Malmö Preventive Project and underwent analysis of: C-terminal endothelin-1 (CT-proET-1), N-Terminal prosomatostatin (NT-proSST), midregional proatrial natriuretic peptide (MR-proANP), procalcitonin (PCT), and copeptin. Participants were followed up for incident PAD and mortality until December 31, 2016. Median follow-up was 11.2 years (interquartile range 9.4-12.2). Cumulative incidence of PAD was 4.3% (

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Hansen, E. "Flow-through (Bio)chemical sensors ? and ?, Elsevier, Amsterdam, 1994. Pages 331. Dfl 355.00 US$202.75. ISBN 0-444-89866-2." Talanta 42, no. 4 (1995): 672. http://dx.doi.org/10.1016/0039-9140(95)90061-6.

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Matsuoka, Satoshi, Hidehiro Kaneko, Akira Okada, et al. "Association between proteinuria and incident colorectal cancer: analysis of a nationwide population-based database." BMJ Open 12, no. 4 (2022): e056250. http://dx.doi.org/10.1136/bmjopen-2021-056250.

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ObjectivesThis study aimed to assess whether adults with proteinuria were at a higher risk of incident colorectal cancer (CRC) than those without proteinuria using a large-scale population-based database.DesignA retrospective observational study.SettingThe JMDC Claims Database, an administrative health claims database, was used. Data were collected between 2005 and 2020.ParticipantsWe selected records of participants (n=3 543 705) who underwent health check-ups, including physical examinations, blood tests and urine dipstick tests. We excluded participants who were aged <20 years (n=25 577)

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Choe, Jeong Cheon, Kwang Soo Cha, Hye Yoon Jang, et al. "Outcomes of Acute Myocardial Infarction Patients Implanted With Biodegradable Polymer Biolimus-Eluting Stents Versus New-Generation Durable Polymer Drug-Eluting Stents: A Retrospective Analysis." Angiology 68, no. 8 (2016): 698–706. http://dx.doi.org/10.1177/0003319716679339.

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We compared outcomes between biodegradable polymer biolimus-eluting stent (BP-BES) and new-generation durable polymer drug-eluting stent (DP-DES) implantations in patients with acute myocardial infarction (MI). Among 13472 patients with acute MI in a nationwide registry, 557 (64.8%) were in the BP-BES and 303 (35.2%) in the new-generation DP-DES group following coronary reperfusion. The occurrence of major adverse cardiac events (MACE; death, MI, revascularization) and stent thrombosis was compared. Major adverse cardiac events occurred in 53 (6.2%) patients and showed similar rates between th

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Hosomi, Sanae, Tetsuhisa Kitamura, Tomotaka Sobue, Ling Zha, Kosuke Kiyohara, and Jun Oda. "Epidemiology and Outcome of Pediatric Out-of-Hospital Cardiac Arrest after Traffic Collision in Japan: A Population-Based Study." Journal of Clinical Medicine 11, no. 3 (2022): 831. http://dx.doi.org/10.3390/jcm11030831.

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The epidemiological and clinical characteristics, treatments, and outcomes of patients with traumatic out-of-hospital cardiac arrests (OHCAs) following traffic collisions have not been adequately investigated in Japan. We analyzed the All-Japan Utstein Registry data of 918 pediatric patients aged <20 years with OHCAs following traffic collisions who were resuscitated by bystanders or emergency medical service personnel and were subsequently transported to hospitals between 2013 and 2019. Multiple logistic regression analysis was used to assess factors potentially associated with 1-month sur

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Srikajornlarp, Saowaluk, Montawatt Amnueypol, Prin Vathesatogkit, et al. "Effectiveness and Safety of Direct Oral Anticoagulants in Thai Patients with Atrial Fibrillation: A Real-World Retrospective Cohort Study." Clinical and Applied Thrombosis/Hemostasis 28 (January 2022): 107602962211300. http://dx.doi.org/10.1177/10760296221130058.

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Background Direct oral anticoagulants (DOACs) are commonly used to prevent stroke and systemic embolism in patients with atrial fibrillation (AF). However, studies into their effectiveness and safety in the Thai population have so far been limited. Objectives To study the effectiveness and safety of warfarin and DOACs among Thai AF patients Methods A retrospective cohort study was conducted on AF patients at Ramathibodi Hospital from 2013 to 2018. All patients were followed for at least 1 year. Relevant clinical information was collected and compared between AF patient groups receiving warfari

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Takahari, Daisuke, Narikazu Boku, Satoru Iwasa, et al. "The new prognostic index of advanced gastric cancer using the data from JCOG1013." Journal of Clinical Oncology 41, no. 4_suppl (2023): 342. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.342.

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342 Background: We previously reported that performance status (PS) ≥1, no prior gastrectomy, number of metastatic sites ≥2, and high serum ALP level are poor prognosis factors and proposed a JCOG prognostic index by analyzing the data of advanced gastric cancer (AGC) patients enrolled in JCOG9912 (Takahari D et al. Oncologist 2014). Recently, Neutrocyte/ Lymphocyte Ratio (NLR) and diffuse type of cancer have also been reported to be prognostic factors of AGC. Methods: Prognostic factors were assessed in patients with AGC who enrolled in JCOG1013, the phase III study comparing docetaxel, cispl

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Chandan, Saurabh, Babu P. Mohan, Shahab R. Khan, et al. "Efficacy and safety of endoscopic ultrasound-guided pancreatic duct drainage (EUS-PDD): A systematic review and meta-analysis of 714 patients." Endoscopy International Open 08, no. 11 (2020): E1664—E1672. http://dx.doi.org/10.1055/a-1236-3350.

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Abstract Background and study aims Endoscopic ultrasound guided pancreatic duct drainage (EUS-PDD) is a minimal-invasive therapeutic option to surgery and in patients with failed endoscopic retrograde pancreatography (ERP). The aim of this review was to quantitatively appraise the clinical outcomes of EUS-PDD by meta-analysis methods. Methods We searched multiple databases from inception through March 2020 to identify studies that reported on EUS-PDD. Pooled rates of technical success, successful drainage of pancreatic duct, clinical success, and adverse events were calculated. Study heterogen

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Molla, Alemayehu, Atikilt Mengesha, Habtamu Derajew, and Habtamu Kerebih. "Suicidal Ideation, Attempt, and Associated Factors among Patients with Tuberculosis in Ethiopia: A Cross-Sectional Study." Psychiatry Journal 2019 (March 13, 2019): 1–10. http://dx.doi.org/10.1155/2019/4149806.

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Background. Suicidal behaviors among people with tuberculosis are one of the commonest psychiatric emergencies that need a major public health concern. People with tuberculosis show suicidal ideation and attempt, which are problems to end life. In Ethiopia large numbers of people are affected by tuberculosis. Therefore, assessing suicide among patients with tuberculosis is important in implementing further interventions. Methods. An institutional based cross-sectional study was conducted among systematic random samples of 415 and face-to-face interview was used. Suicidal ideation and attempt w

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Naderemu, Paermanjiang, Jun-shi Zhang, Hai-ming Liu, and Xin-juan Xu. "Correlation of 24-Hour Urinary Microalbumin and Atrial Arrhythmia in Patients With Essential Hypertension." American Journal of Hypertension 35, no. 6 (2022): 572. http://dx.doi.org/10.1093/ajh/hpab180.

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Abstract Background To investigate the relationship between 24-hour urinary microalbumin (24h-UmAlb) and atrial arrhythmia in patients with essential hypertension (EH). Methods From March 2018 to January 2020, 917 EH patients at First Affiliated Hospital of Xinjiang Medical University were enrolled, and divided into nonatrial arrhythmia and atrial arrhythmia groups according to their 24-hour dynamic electrocardiography. The general clinical data and laboratory test parameters were compared. Results Compared with patients without atrial arrhythmia, the 24-UmAlb level was higher in patients with

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Røysted-Solås, Therese, Sven Gudmund Hinderaker, Lasantha Ubesekara, and Vijitha De Silva. "Mothers at risk of postpartum depression in Sri Lanka: A population-based study using a validated screening tool." PLOS ONE 17, no. 5 (2022): e0268748. http://dx.doi.org/10.1371/journal.pone.0268748.

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Background Postpartum depression is an important public health concern. The prevalence of postpartum depression is estimated to be 18% worldwide. The purpose of this study was to estimate the prevalence of mothers at risk of postpartum depression in Sri Lanka and to investigate its associated risk factors. Methods This was a cross-sectional study conducted among 975 mothers in Galle district, Sri Lanka. The prevalence of mothers at risk of postpartum depression was assessed using the Edinburgh Postpartum Depression scale (EPDS) which has been validated for screening for mothers at risk of post

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Sánchez Macarro, Maravillas, Vicente Ávila-Gandía, Silvia Pérez-Piñero, et al. "Antioxidant Effect of a Probiotic Product on a Model of Oxidative Stress Induced by High-Intensity and Duration Physical Exercise." Antioxidants 10, no. 2 (2021): 323. http://dx.doi.org/10.3390/antiox10020323.

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This randomized double-blind and controlled single-center clinical trial was designed to evaluate the effect of a 6-week intake of a probiotic product (1 capsule/day) vs. a placebo on an oxidative stress model of physical exercise (high intensity and duration) in male cyclists (probiotic group, n = 22; placebo, n = 21). This probiotic included three lyophilized strains (Bifidobacterium longum CECT 7347, Lactobacillus casei CECT 9104, and Lactobacillus rhamnosus CECT 8361). Study variables were urinary isoprostane, serum malondialdehyde (MDA), serum oxidized low-density lipoprotein (Ox-LDL), ur

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Zutshi, Anita, Jayasree Santhosh, Julie Sheikh, et al. "Implications of Early Pregnancy Obesity on Maternal, Fetal and Neonatal Health: Retrospective cohort study from Oman." Sultan Qaboos University Medical Journal [SQUMJ] 18, no. 1 (2018): 47. http://dx.doi.org/10.18295/squmj.2018.18.01.008.

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Objectives: This study aimed to determine the prevalence of early pregnancy obesity among Omani women and to review maternal antenatal complications, intrapartum and postpartum events and neonatal complications among such women in comparison to women of normal weight. Methods: This retrospective cohort study included 2,652 pregnant Omani women who delivered at the Royal Hospital, Muscat, Oman, between November 2011 and April 2012. The patients’ electronic medical records were reviewed for antenatal, intrapartum and postpartum data. Body mass index was measured during the first trimester (≤12 g

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Lam, Tai Hing, Mohsen Janghorbani, Susan Fan, and Richard Fielding. "Voluntary HIV antibody testing amongst youth in Hong Kong." International Journal of STD & AIDS 14, no. 2 (2003): 132–38. http://dx.doi.org/10.1258/095646203321156917.

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We performed a study to estimate the prevalence of and factors associated with human immunodeficiency virus (HIV) antibody-testing behaviour among youth in Hong Kong. It was a population-based cross-sectional study. Questions on HIV testing were asked as part of a youth sexuality study conducted in July to December 1996 among young adults in Hong Kong. A total of 517 (53.6%) males and 447 (46.4%) females aged 17 to 28 years completed an anonymous structured self-administered questionnaire. Respondents had good knowledge about correct modes of HIV transmission and prevention. 9.4% (95% confiden

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Grant, Rebecca, Olivier Flechelles, Narcisse Elenga, et al. "Consequences of In Utero Zika Virus Exposure and Adverse Pregnancy and Early Childhood Outcomes: A Prospective Cohort Study." Viruses 14, no. 12 (2022): 2755. http://dx.doi.org/10.3390/v14122755.

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We aimed to describe adverse pregnancy outcomes among women who had symptomatic, RT-PCR-confirmed ZIKV infection and early childhood outcomes among their infants. We enrolled pregnant women with symptomatic, RT-PCR-confirmed ZIKV infection in a prospective cohort study, and their infants in a prospective pediatric cohort study. We defined adverse pregnancy and early childhood outcomes based on selected neurologic, ophthalmologic, auditory, musculoskeletal, and anthropometric abnormalities. We used RT-PCR and serologic tests to determine the ZIKV infection status of the child. Between 10 March

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Shephard, Elizabeth A., Molly AL Parkinson, and William T. Hamilton. "Recognising laryngeal cancer in primary care: a large case–control study using electronic records." British Journal of General Practice 69, no. 679 (2019): e127-e133. http://dx.doi.org/10.3399/bjgp19x700997.

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BackgroundOver 1700 people are diagnosed with laryngeal cancer annually in England. Current National Institute for Health and Care Excellence (NICE) guidelines on referral for suspected laryngeal cancer were based on clinical consensus, in the absence of primary care studies.AimTo identify and quantify the primary care features of laryngeal cancer.Design and settingMatched case–control study of patients aged ≥40 years using data from the UK’s Clinical Practice Research Datalink.MethodClinical features of laryngeal cancer with which patients had presented to their GP in the year before diagnosi

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Rodseth, Reitze N., Bruce M. Biccard, Rong Chu, et al. "Postoperative B-type Natriuretic Peptide for Prediction of Major Cardiac Events in Patients Undergoing Noncardiac Surgery." Anesthesiology 119, no. 2 (2013): 270–83. http://dx.doi.org/10.1097/aln.0b013e31829083f1.

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Abstract Background: It is unclear whether postoperative B-type natriuretic peptides (i.e., BNP and N-terminal proBNP) can predict cardiovascular complications in noncardiac surgery. Methods: The authors undertook a systematic review and individual patient data meta-analysis to determine whether postoperative BNPs predict postoperative cardiovascular complications at 30 and 180 days or more. Results: The authors identified 18 eligible studies (n = 2,051). For the primary outcome of 30-day mortality or nonfatal myocardial infarction, BNP of 245 pg/ml had an area under the curve of 0.71 (95% CI,

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Kaur-Knudsen, Diljit, Stig E. Bojesen, Anne Tybjærg-Hansen, and Børge G. Nordestgaard. "Nicotinic Acetylcholine Receptor Polymorphism, Smoking Behavior, and Tobacco-Related Cancer and Lung and Cardiovascular Diseases: A Cohort Study." Journal of Clinical Oncology 29, no. 21 (2011): 2875–82. http://dx.doi.org/10.1200/jco.2010.32.9870.

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Purpose We examined the associations between the nicotinic acetylcholine receptor polymorphism (rs1051730) on chromosome 15q25 marking the gene cluster CHRNA3-CHRNB4-CHRNA5, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases in the general population. Methods Ten thousand three hundred thirty participants from the Copenhagen City Heart Study were genotyped and observed prospectively with up to 18 years of 100% complete follow-up. Smoking behavior was measured at baseline. End points were lung cancer, bladder cancer, chronic obstructive pulmonary disease, ischemic

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Yoon, D., M. Ryu, Y. Park, et al. "Phase II study of everolimus in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum." Journal of Clinical Oncology 29, no. 4_suppl (2011): 93. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.93.

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93 Background: To evaluate feasibility with activity and toxicities of everolimus, a novel inhibitor of mammalian target of rapamycin (mTOR), in patients with advanced gastric cancer (AGC) who failed chemotherapy including both fluoropyrimidine and platinum (FP). Methods: Fifty-four patients were enrolled between Jul 2008 and Feb 2010. Everolimus, 10 mg daily, was given until disease progression or unacceptable toxicity. Primary objective was to determine 4-month progression-free survival (PFS) and secondary objectives were to investigate response rate, toxicity and overall survival OS rate. P

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Moradi, Asaad, Mohammad Zamani, and Emadoddin Moudi. "A systematic review and meta-analysis on incidence of prostate cancer in Iran." Health Promotion Perspectives 9, no. 2 (2019): 92–98. http://dx.doi.org/10.15171/hpp.2019.13.

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Background: Prostate cancer is a global health concern. In Iran, its epidemiology is not precisely recognized. We aimed to evaluate incidence of prostate cancer among Iranian populations. Methods: In this systematic review, we searched the databases PubMed, Web of Sciences, Scopus and Google Scholar for English studies and the databases Magiran, Scientific information Database, IranMedex and IranDoc for Persian studies, using related keywords. The cross sectional articles published from inception to 31 December 2018 were included. Meta-analysis was conducted on the collected data with STATA so

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Merianos, Ashley L., Tierney F. Mancuso, Judith S. Gordon, Kelsi J. Wood, Katherine A. Cimperman, and E. Melinda Mahabee-Gittens. "Dual- and Polytobacco/Nicotine Product Use Trends in a National Sample of High School Students." American Journal of Health Promotion 32, no. 5 (2017): 1280–90. http://dx.doi.org/10.1177/0890117117743361.

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Purpose: The study purpose was to examine changes in patterns of ever and current dual- and polyproduct use over time and to examine demographic and modifiable risk factors including tobacco smoke exposure (TSE). Design: A secondary analysis of the 2013 to 2015 National Youth Tobacco Survey data. Setting: Nationwide high schools were selected. Subjects: A total of 31 022 high school students. Measures: Ever and current (past 30 days) tobacco/nicotine product use, home tobacco/nicotine product use, TSE and e-cigarette vapor exposure, and demographic characteristics were measured. Analysis: Mult

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Mohammed-Nour, Ahmed, Mohamed Al-Sewailem, and Ahmed H. El-Naggar. "The Influence of Alkalization and Temperature on Ammonia Recovery from Cow Manure and the Chemical Properties of the Effluents." Sustainability 11, no. 8 (2019): 2441. http://dx.doi.org/10.3390/su11082441.

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Manure is a substantial source of ammonia volatilization into the atmosphere before and after soil application. The purpose of the study was to investigate the effects of temperature and alkalization treatments on the release of ammonia and ammonia recovery (AR) from cow manure and to characterize the chemical properties of the resultant effluents. In a closed glass reactor, 100 g of fresh cow manure was mixed with 100 mL of deionized water and the mixture was treated with various volume of KOH to increase the manure pH to 7, 9, and 12. Ammonia was distilled from the mixture at temperatures of

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Lavery, Lawrence A., David C. Lavery, Nathan A. Hunt, Javier La Fontaine, and Ryan D. Lavery. "Does the Start of Dialysis Initiate a Period of Increased Risk of Ulceration or Amputation?" Journal of the American Podiatric Medical Association 108, no. 1 (2018): 1–5. http://dx.doi.org/10.7547/16-056.

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Background: Dialysis therapy is associated with an increased incidence of lower-extremity wounds and amputations. We compared the incidence of foot ulcers and amputations before and after the start of dialysis. Methods: We evaluated 150 consecutive diabetic patients receiving dialysis and compared the incidence of foot complications 30 months before and after initiation of hemodialysis. We used claims data for diabetes, ulceration, and dialysis and abstracted medical records to verify diagnoses and dates of ulcers and amputations. We compared initial and cumulative ulcer/amputation incidence t

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Sherry, J. "Innkeeper's liability management by Gary M. Bakker and John R. Abele, Lawyers and Judges Publishing Company, 917 North Swan Road, Suite 300, Tucson, Arizona 85711-1213, © 1995, 448 pp., hard cover, $71.50." Cornell Hotel and Restaurant Administration Quarterly 36, no. 5 (1995): 17. http://dx.doi.org/10.1016/0010-8804(95)80018-2.

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Guo, Jing, David I. Givens, and Berit Lilienthal Heitmann. "Association between dairy consumption and cardiovascular disease events, bone fracture and all-cause mortality." PLOS ONE 17, no. 9 (2022): e0271168. http://dx.doi.org/10.1371/journal.pone.0271168.

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Dairy products are important constituents of a healthy and balanced diet, but their association with health outcomes remains to be established. We investigated the association of total dairy, total fermented dairy, and different dairy subtypes (including total/high-fat/low-fat milk, yogurt, cheese, butter, and cream) and the risk of cardiovascular disease (CVD), coronary heart disease (CHD), bone fracture and all-cause mortality among 1746 Danish healthy men and women (30–60 years, 52%female). Hazard ratios (HRs) and 95% CIs were estimated using the multivariable Cox proportional hazard models

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Meloni, Marco, Valentina Izzo, Laura Giurato, Enrico Brocco, Roberto Gandini, and Luigi Uccioli. "Limb Salvage in Diabetic Patients With Ischemic Heel Ulcers." International Journal of Lower Extremity Wounds 19, no. 3 (2019): 275–81. http://dx.doi.org/10.1177/1534734619884438.

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The purpose of this study is to investigate the outcomes of diabetic individuals with ischemic heel ulcers. The study group was composed of a consecutive sample of persons with diabetic ischemic foot ulcers managed by a preset multidisciplinary limb salvage protocol, including revascularization through endovascular technique. The outcome measures were healing, major amputation (above the ankle), and death at 1-year of follow-up. The outcomes between patients with heel ulcers (HUs) and without (NHUs) were compared. A total of 254 patients were recruited. There were 50/254 (19.7%) HUs and 204/25

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Ambarsari, Cahyani Gita, Partini Pudjiastuti Trihono, Agustina Kadaristiana, et al. "Five-year experience of continuous ambulatory peritoneal dialysis in children: a single center experience in a developing country." Medical Journal of Indonesia 28, no. 4 (2019): 329–37. http://dx.doi.org/10.13181/mji.v28i4.3807.

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BACKGROUND The pediatric peritoneal dialysis (PD) program in Cipto Mangunkusumo Hospital, Indonesia was started in 2014. However, there has been no published data on the patients’ outcome. This study was aimed to report the characteristics and outcomes of a continuous ambulatory peritoneal dialysis (CAPD) program for children. METHODS This retrospective study was conducted in Cipto Mangunkusumo Hospital as a national referral hospital. Data were collected from medical records of patients aged ≤18 years with end-stage renal disease who underwent CAPD in 2014–2019. The baseline characteris

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