Auswahl der wissenschaftlichen Literatur zum Thema „Antineoplastika“

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Zeitschriftenartikel zum Thema "Antineoplastika"

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Kreutzberger, Alfred, and Elfriede Kreutzberger. "Antineoplastika, 15. Mitt. Butylderivate der 5-Aminomethylenbarbitursäure." Archiv der Pharmazie 318, no. 9 (1985): 821–24. http://dx.doi.org/10.1002/ardp.19853180910.

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Kreutzberger, Alfred, and Michael Sellheim. "Antineoplastika XVI [1]. 4-Alkyl-6-trifluormethyl-2-ureidopyrimidine." Journal of Fluorine Chemistry 27, no. 2 (1985): 203–12. http://dx.doi.org/10.1016/s0022-1139(00)84989-1.

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Kreutzberger, Alfred, Peter Langner, and Jörg Stratmann. "Antineoplastika, 19. Mitt.: Darstellung vonN-[2-Chlor-4-diethylamino-(1,3,5-triazin-6-yl)]-aminosäuren." Archiv der Pharmazie 323, no. 12 (1990): 995–96. http://dx.doi.org/10.1002/ardp.19903231211.

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Kreutzberger, Alfred, Peter Langner, and Jörg Stratmann. "Antineoplastika, 17. Mitt.1): Darstellung mono- und disubstituierter 2,4-Dichlor-6-diethylamino-1,3,5-triazine." Archiv der Pharmazie 324, no. 3 (1991): 173–76. http://dx.doi.org/10.1002/ardp.19913240308.

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Kopjar, Nevenka, Davor Želježić, Vilena Kašuba, and Ružica Rozgaj. "Antineoplastic Drugs as a Potential Risk Factor in Occupational Settings: Mechanisms of Action at the Cell Level, Genotoxic Effects, and Their Detection Using Different Biomarkers." Archives of Industrial Hygiene and Toxicology 61, no. 1 (2010): 121–46. http://dx.doi.org/10.2478/10004-1254-61-2010-2025.

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Antineoplastični Lijekovi Kao Čimbenik Rizika u Radnom Okolišu: Mehanizmi Djelovanja na Razini Stanice i Pregled Metoda za Otkrivanje Njihovih Genotoksičnih UčinakaU članku je prikazana osnovna podjela antineoplastičnih lijekova prema mehanizmima djelovanja na razini stanice. Objašnjeni su mehanizmi genotoksičnosti najvažnijih vrsta lijekova koji se primjenjuju u okviru uobičajenih protokola za liječenje zloćudnih novotvorina. Navedena je važeća klasifikacija antineoplastika prema kancerogenom potencijalu, podaci o mutagenom potencijalu te je prikazana njihova podjela u skladu s anatomsko-tera
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Burgaz, S., B. Karahalil, Z. Canli, et al. "Assessment of genotoxic damage in nurses occupationally exposed to antineoplastics by the analysis of chromosomal aberrations." Human & Experimental Toxicology 21, no. 3 (2002): 129–35. http://dx.doi.org/10.1191/0960327102ht230oa.

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To estimate the genotoxic risk of occupational exposure to antineoplastic drugs, chromosomal aberration (CAs) frequencies in peripheral lymphocytes were determined for 20 nurses handling antineoplastics and 18 referents matched for age and sex. Urinary cyclophosphamide (CP) excretion rates, which are used as a marker for drug handling, were also measured on these nurses. We have observed significant frequencies of CAs (about 2.5-fold increase) including chromatid breaks, gaps, and acentric fragments for nurses handling antineoplastics as compared to control subjects (p<0.05, p<0.01, excl
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Birken, Sarah A., Alexandra Peluso, Cheyenne Wagi, et al. "Continued outpatient oncology care for cancer survivors by antineoplastic medication use: Identifying opportunities for stratified survivorship care." Journal of Clinical Oncology 40, no. 28_suppl (2022): 226. http://dx.doi.org/10.1200/jco.2022.40.28_suppl.226.

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226 Background: Cancer survivors may be more likely to receive preventive care services when they see both oncologists and PCPs; however, some oncology visits may not be necessary, straining limited subspecialty resources. In this study, we quantified outpatient primary and oncology care utilization in the years surrounding cancer diagnosis. We further characterized the proportion of survivors with oncology visits in the absence of ongoing antineoplastic use, as we hypothesized these survivors might be appropriate for need- and risk-stratified survivorship care, a model successful outside the
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Guan, Xiaodong, Haishaerjiang Wushouer, Mingchun Yang, et al. "Influence of government price regulation and deregulation on the price of antineoplastic medications in China: a controlled interrupted time series study." BMJ Open 9, no. 11 (2019): e031658. http://dx.doi.org/10.1136/bmjopen-2019-031658.

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BackgroundIn October 2012, the Chinese government established maximum retail prices for specific products, including 30 antineoplastic medications. Three years later, in June 2015, the government abolished price regulation for most medications, including all antineoplastic medications. This study examined the impacts of regulation and subsequent deregulation of prices of antineoplastic medications in China.MethodsUsing hospital procurement data and an interrupted time series with comparison series design, we examined the impacts of the policy changes on relative purchase prices (Laspeyres pric
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McNabb, Lorna, Eva Metrot, Micaela Ferrington, et al. "Assessment of patient perceptions of counselling on oral antineoplastic agents by a dedicated cancer services pharmacist in an outpatient cancer clinic." PLOS ONE 19, no. 6 (2024): e0304011. http://dx.doi.org/10.1371/journal.pone.0304011.

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Background Oral antineoplastic agents have caused a paradigm shift in cancer treatment, however, they produce many unique challenges. Although oral antineoplastics can have complex administration regimes, low adherence rates and high possibilities of drug-drug interactions, they are administered unsupervised at home. Cancer services pharmacists have the required skillsets to improve patient outcomes associated with oral antineoplastic treatment by increasing patient health literacy, improving concordance and optimising administration protocols. Aim To evaluate patients’ perceptions, experience
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Hong, Samuel J., Edward C. Li, Linda M. Matusiak, and Glen T. Schumock. "Spending on Antineoplastic Agents in the United States, 2011 to 2016." Journal of Oncology Practice 14, no. 11 (2018): e683-e691. http://dx.doi.org/10.1200/jop.18.00069.

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Purpose: Recent cancer drug approvals are lauded as being more effective with relatively fewer adverse effects, but these treatments come with a great cost to the US health care system. There is little information on recent trends in actual antineoplastic expenditures representative of the whole US health care system or by sector. Therefore, the objective of this study was to describe antineoplastic expenditures in the United States by year and sector. Methods: This was a retrospective, cross-sectional study of IQVIA (formerly QuintilesIMS) National Sales Perspective data for the period of Jan
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Dissertationen zum Thema "Antineoplastika"

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Varrica, Maria Giulia Sara. "Sintesi di isossazolidinil-ipa ad arrività antineoplastica." Doctoral thesis, Università di Catania, 2014. http://hdl.handle.net/10761/1546.

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Nel lavoro oggetto della tesi di dottorato viene riportata la sintesi e l attività antineoplastica di una serie di idrocarburi policiclici aromatici (IPA) a core isossazolidinico, isossazolinico ed isossazolico. I composti sono stati preparati per cicloaddizione 1,3-dipolare di nitroni e nitril ossidi con dipolarofili variamente sostituiti. L attività antitumorale è stata valutata su tre linee cellulari (HeLa, HN6, HN13) mediante saggio MTS. I risultati ottenuti mostrano che i derivati isossazolidinici presentano le migliori proprietà; in particolare, il (3R,5S)-3-(1,10-fenantrolin-2-il)-2-(2-
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RAIMONDI, Maria Valeria. "SINTESI ED ATTIVITÀ ANTINEOPLASTICA DI NUOVI COMPOSTI ETEROCICLICI." Doctoral thesis, Università degli Studi di Palermo, 2004. http://hdl.handle.net/10447/365532.

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Danica, Jović. "Sinteza, karakterizacija i biološka ispitivanja fulerenol/doksorubicin nanokompozita." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2018. https://www.cris.uns.ac.rs/record.jsf?recordId=106903&source=NDLTD&language=en.

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U radu je predstavljena sinteza i karakterizacija  novog fulerenol/doksorubicin nanokompozita, sintetisanog sa ciljem dobijanja potencijalne nove nanoformulacije postojećeg antineoplastika doksorubicina, koja bi pokazala veću biološku aktivnost uz smanjenje neželjenih sporednih efekata koje sam lek izaziva, na prvom mestu kardiotoksičnosti.Nanokompozit fulerenol/doksorbicin je okarakterisan brojnim  metodama prateći dva osnovna eksperimentalna pristupa: molekulsko-spektroskopske metode (XPS, denzitometrija i transportne osobine, NMR, UPLC, Ramanska i UV-spektroskopija, SFM) i
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Wan, Jung Wing. "Novel ether lipids as antineoplastic agents." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242627.

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Conesa, Milián Laura. "Synthesis of combretastatin analogues with antineoplastic properties." Doctoral thesis, Universitat Jaume I, 2019. http://hdl.handle.net/10803/667097.

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This doctoral thesis belongs to the field of medicinal and pharmacological chemistry. Its aim is the synthesis, characterization and biological evaluation of three families of aminocombretastatin derivatives, compound with antimitotic and antiangiogenic properties. The first group contains a carbamate function in its structure. These derivatives have been studied as antimitotic and vascular disrupting agents. The second family has been designed from sorafenib drug, with the aim of studying its antiangiogenic effects. Regarding the third family, these have been designed as multitarget compo
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Molyneux, Gemma. "Studies on the haemotoxicity of antineoplastic agents." Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435080.

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Chen, Alina. "New polyamine analogues as potential antineoplastic agents." Scholarly Commons, 2000. https://scholarlycommons.pacific.edu/uop_etds/2680.

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The naturally occurring polyamines play an essential role in cell growth and proliferation. The levels of polyamines have been shown to increase in rapidly proliferating cancer cells. Therefore, compounds that inhibit enzymes in polyamine biosynthetic pathway may have therapeutic potential. Compounds capable of providing both in vitro and in vivo inhibition of almost all enzymes in the polyamine biosynthetic pathway are known. An exception is the lack of an agent that inhibits spermidine/spermine N 1 -acetyltransferase (SSAT), the rate-limiting enzyme in the catabolism of polyamines. The desig
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Hedmer, Maria. "Monitoring of occupational exposure to antineoplastic drugs." Malmö : Lund University, 2006. http://theses.lub.lu.se/scripta-archive/2006/04/18/med_1298/Maria_H_kappa.pdf.

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Bossaer, John B. "Addressing Potential Interactions Between Antineoplastics and Dietary Supplements." Digital Commons @ East Tennessee State University, 2015. https://doi.org/10.2146/ajhp140295.

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Rey, Allan W. "Synthetic studies directed towards the antineoplastic macrolide bryostatins." Thesis, University of Ottawa (Canada), 1990. http://hdl.handle.net/10393/5938.

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This thesis describes stereocontrolled and practical routes to the C(1)-C(9), C(17)-C(20), and C(21)-C(27) synthons of bryostatins, which are a closely related family of 20-membered ring lactones embedding 1,3-polyol units. Bryostatins are isolated in minute quantities from the marine Bryozoan Bugula neritina and possess exceptional antineoplastic activity. Membrane-enclosed enantioselective enzymatic hydrolysis was successfully employed for the generation of gram quantities of the versatile building block (3R)-methoxymethoxypentadioic acid, monomethyl ester (51) (Chapter 2). This compound was
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Bücher zum Thema "Antineoplastika"

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Lednicer, Daniel. Antineoplastic Drugs. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118892572.

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David, Kessel, ed. Resistance to antineoplastic drugs. CRC Press, 1989.

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Milne, George W. A., 1937-, ed. Ashgate handbook of antineoplastic agents. Ashgate, 2000.

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David, Goldman I., ed. Membrane transport of antineoplastic agents. Pergamon Press, 1986.

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1950-, Schilsky Richard L., Milano Gérard A. 1952-, and Ratain Mark J. 1954-, eds. Principles of antineoplastic drug development and pharmacology. M. Dekker, 1996.

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Chow, Nang-Ly. Liposomes as carriers of antineoplastic agents and immunomodulators. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, International Cancer Research Data Bank, 1989.

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1932-, Borders Donald B., and Doyle Terrence W. 1942-, eds. Enediyne antibiotics as antitumor agents. M. Dekker, 1995.

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E, Wittes Robert, and National Cancer Institute (U.S.), eds. Compilation of phase II results with single antineoplastic agents. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, 1986.

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National Institutes of Health (U.S.), ed. Compilation of phase II results with single antineoplastic agents. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, 1985.

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IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Some antiviral and antineoplastic drugs, and other pharmaceutical agents. IARC, 2000.

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Buchteile zum Thema "Antineoplastika"

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Markman, Maurie. "Das Dosis-Wirkung-Prinzip in Verbindung mit der Zufuhr von Antineoplastika." In Regionale Therapie maligner Tumoren. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-35014-6_2.

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Champagne, Trevor. "Antineoplastics." In Litt's Drug Eruption & Reaction Manual, 31st ed. CRC Press, 2025. https://doi.org/10.1201/9781003569756-1508.

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O'brien, Wendy Pott. "Antineoplastic Agents." In Physiologically Based Pharmacokinetic Modeling. John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471478768.ch11.

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Patsalos, P. N. "Antineoplastic Agents." In Antiepileptic Drug Interactions. Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-2434-4_57.

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Patsalos, Philip N. "Antineoplastic Agents." In Antiepileptic Drug Interactions. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32909-3_61.

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Kirschenbaum, Harold L., and Michelle M. Kalis. "Antineoplastic Agents." In The Pharmacy Practice Handbook of Medication Facts. Routledge, 2023. http://dx.doi.org/10.4324/9780429272783-7.

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Patsalos, Philip N. "Antineoplastic Agents." In Antiseizure Medication Interactions. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-82790-8_68.

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Schultz, Kathryn, and Eris Tollkuci. "Antineoplastic Therapy." In O'Donnell's Drug Injury, 5th ed. CRC Press, 2025. https://doi.org/10.1201/9781003615323-18.

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Schmähl, D., M. R. Berger, B. K. Keppler, and T. Klenner. "New Antineoplastic Agents." In Cancer Therapy. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74683-3_11.

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Patel, Jai N., Christine M. Walko, and Federico Innocenti. "Pharmacogenetics and Antineoplastic Therapies." In Advances in Predictive, Preventive and Personalised Medicine. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-15344-5_10.

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Konferenzberichte zum Thema "Antineoplastika"

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Silva, Sâmela Maria de Oliveira, Manuelle de Araujo Holanda, Thaísa Mirella da Silva, Clebiana Alves e. silva Diniz, and Suzana Maria de Oliveira Costa Meneses. "Role of oncological nursing in stroke of antineoplastic drugs." In II INTERNATIONAL SEVEN MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/homeinternationalanais-044.

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Abstract Exposure to antineoplastic drugs poses a potential risk to the health of professionals who handle, administer and dispose of them. The risk of harmful effects arising from exposure to the cytotoxic properties of antineoplastic agents is not restricted to patients, and health professionals may also experience cellular and clinical changes related to occupational exposure to these substances. Professional exposure can occur at any time during the handling of chemotherapy, whether in preparation, administration or disposal.
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Ditto, Andrew J., Nikki K. Robbishaw, Matthew J. Panzner, Wiley J. Youngs, and Yang H. Yun. "Targeting Ovarian Cancer Cells With Rapidly Biodegradable L-Tyrosine Polyphosphate Nanoparticles Decorated With Folate." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53138.

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Chemotherapy employs toxic chemicals to kill rapidly dividing cells. Examples of FDA approved antineoplastic drugs include cisplatin, doxorubicin, and paclitaxel. Since most of these drugs are nonspecific, they also damage normal tissues as well as the aberrant tumors. As a result, non-specific therapies have multiple side effects, which include myelosuppression, mucositis, alopecia, nephrotoxicity, and genotoxcity. In order to minimize these issues, researchers have begun to conjugate antineoplastic chemicals with targeting moieties or encapsulate drugs into nanoparticles decorated with compo
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Sieber, Fritz. "Antineoplastic And Antiviral Properties Of Merocyanine 540." In O-E/Fiber LASE '88, edited by Tayyaba Hasan. SPIE, 1989. http://dx.doi.org/10.1117/12.960195.

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Medina, Luis Alberto. "Liposomes as delivery systems for antineoplastic drugs." In XIII MEXICAN SYMPOSIUM ON MEDICAL PHYSICS. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4901357.

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Brito, Poliana Silva de, Nataniele de Albuquerque, Tainan de Andrade Rocha, Clebiana Alves e. silva Diniz, and Julia Maria Pacheco Lins Magalhães. "Knowledge of nursing professionals about the use of personal protection equipment in the administration of antineoplastic chemotherapy." In II INTERNATIONAL SEVEN MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/homeinternationalanais-035.

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Abstract The professional who manipulates antineoplastic chemotherapy without the proper use of Personal Protective Equipment (PPE) is at risk of presenting from simple symptoms such as headache, dizziness, vomiting, alopecia, allergic reactions and mucosa alterations, to more serious effects, such as: mutagenicity, carcinogenicity and teratogenicity, caused by the undue absorption of these substances.
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Alonso Castro, V., B. López Centeno, I. Martín Casasempere, et al. "4CPS-105 Prescribed antineoplastic agents in paediatric patients." In 24th EAHP Congress, 27th–29th March 2019, Barcelona, Spain. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/ejhpharm-2019-eahpconf.254.

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Deroubaix, F., T. Ameye, V. Moinard, and J. Gressier. "PP-048 Antineoplastics: anticipated preparations or longer opening hours?" In 22nd EAHP Congress 22–24 March 2017 Cannes, France. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/ejhpharm-2017-000640.495.

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Yoon, Seug Yun, Namsu Lee, Sook-Ja Kim, Hee-Jeong Cheong, Kyoung Ha Kim, and Jong-Ho Won. "Abstract 3843: Pulmonary toxicities of molecular targeted antineoplastic agents." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3843.

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Labrèche, F., B. Roberge, A. Yennek, NJ Caron, and J.-F. Bussières. "1508 Is hospital sanitation personnel exposed to antineoplastic agents?" In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.923.

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Pires, T., D. Almeida, J. Joaquim, J. Lopes, and C. Matos. "PP-052 Surface contamination of antineoplastics due to working procedures." In 22nd EAHP Congress 22–24 March 2017 Cannes, France. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/ejhpharm-2017-000640.499.

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Berichte der Organisationen zum Thema "Antineoplastika"

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Huang, Yi. Antineoplastic Efficacy of Novel Polyamine Analogues in Human Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427952.

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Huang, Yi. Antineoplastic Efficacy of Novel Polyamine Analogues in Human Breast Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada460069.

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Huang, Yi. Antineoplastic Efficacy of Novel Polyamine Analogues in Human Breast Cancer. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada478464.

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Berger, Martin R. Antineoplastic activity of cucurbitacin I in CC531 rat colorectal cancer cells. Science Repository OÜ, 2019. http://dx.doi.org/10.31487/j.cor.2019.01.105.

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Koutcher, Jason A. Non-Invasive Markers of Tumor Growth, Metastases and Sensitivity to AntiNeoplastic Therapy. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada460278.

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Antineoplastic agents - occupational hazards in hospitals. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 2004. http://dx.doi.org/10.26616/nioshpub2004102.

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Preventing occupational exposures to antineoplastic and other hazardous drugs in health care settings. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 2004. http://dx.doi.org/10.26616/nioshpub2004165.

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Preventing occupational exposures to antineoplastic and other hazardous drugs in health care settings. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 2004. http://dx.doi.org/10.26616/nioshpub2004165a.

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NIOSH list of antineoplastic and other hazardous drugs in healthcare settings, 2016. (Supersedes 2014-138). U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 2016. http://dx.doi.org/10.26616/nioshpub2016161.

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NIOSH list of antineoplastic and other hazardous drugs in healthcare settings 2010 (superseded by 2012-150). U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 2010. http://dx.doi.org/10.26616/nioshpub2010167.

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