Thematische Bibliographien / Bulk Drug

Inhaltsverzeichnis

  1. Zeitschriftenartikel
  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte
  6. Berichte der Organisationen

Auswahl der wissenschaftlichen Literatur zum Thema „Bulk Drug“

Autor: Grafiati
Veröffentlicht am 7. Juni 2025
Zuletzt aktualisiert am 2. August 2025

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Zeitschriftenartikel zum Thema "Bulk Drug"

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STINSON, STEPHEN C. "Bulk Drug Output Moves Outside U.S." Chemical & Engineering News 63, no. 37 (1985): 25. http://dx.doi.org/10.1021/cen-v063n037.p025.

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Teske, Michael, Katharina Wulf, Daniela Arbeiter, Thomas Eickner, Klaus-Peter Schmitz, and Niels Grabow. "Influence of bulk incorporation of FDAc and PTX on polymer properties." Current Directions in Biomedical Engineering 3, no. 2 (2017): 691–94. http://dx.doi.org/10.1515/cdbme-2017-0146.

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AbstractIn the last decades PLLA-based copolymers have been among the most attractive polymeric candidates used to fabricate devices for drug delivery and stent applications in the cardiovascular system. PLLA is biocompatible and biodegradable, exhibits a wide range of erosion times and has tunable mechanical properties. Therefore, the influence of drug incorporation on the physicochemical properties of biodegradable PLLA copolymers were examined in this study using Fluorescein diacetate (FDAc) and Paclitaxel (PTX). A percental amount of these drugs (17.5 %) were incorporated into poly(L-lacti
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Dipannita, Naskar Dr. Subharota Majumdar Banhishikha Kar. "UV Spectrophotometric Method Development and Validation for the Determination of Fluoxetine Hydrochloride in Bulk Drug and Commercial Formulation." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4827–34. https://doi.org/10.5281/zenodo.15547480.

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The simple and rapid spectrophotometric technique has been developed to measure and validate the absorbance of antidepressant drug fluoxetine hydrochloride. This study's objective is to use UV spectroscopy to precisely and accurately estimate the maximum wavelength of the bulk drug and the pH at which the bulk drug exhibits the highest absorbance. According to Beer’s law concentration range of bulk drug and sample is 2-20µg/ml in buffer at pH 1.2, 6.8 and 7.4 respectively. The ℷmax of the bulk drug is 226nm. The linear regression equations of bulk drug were determined to be y = 00.
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Eggertson, L. "Federal legislation to limit bulk drug exports." Canadian Medical Association Journal 173, no. 3 (2005): 242. http://dx.doi.org/10.1503/cmaj.050813.

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Novoa de Armas, Héctor, Rolando González Hernández, Anailien Boza Rivera, Ramón Pomés Hernández, and Irminia Herrera Martínez. "Crystal pseudopolymorphism of secnidazole bulk drug, C7H11N3O3." Powder Diffraction 14, no. 2 (1999): 136–41. http://dx.doi.org/10.1017/s0885715600010459.

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An indexed powder diffraction pattern and related crystallographic data are reported for secnidazole [C7H11N3O3, IUPAC name: 1-(2-hydroxypropyl)-2-methyl-5-nitroimidazole], which is not represented in the Powder Diffraction File. The unit cell dimensions were determined from diffractometer methods, using monochromatic CuKα1 radiation, and evaluated by indexing programs. The monoclinic cell found for 1-(2-hydroxypropyl)-2-methyl-5-nitroimidazole is: a=12.426(2) Å, b=12.173(2) Å, c=6.656(1) Å, β=100.19(1)°, Z=4, space group P21/c (No. 14), Dx=1.271 g/cm3. Crystallization of an anhydrous powdered
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THAYER, ANN. "Midsized Drug Firms Bulk Up With Mergers." Chemical & Engineering News 78, no. 38 (2000): 16. http://dx.doi.org/10.1021/cen-v078n038.p016.

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Kulthe, V. V., and P. D. Chaudhari. "UV SPECTROPHOTOMETRIC ESTIMATION OF ACETAZOLAMIDE BY STANDARD CALIBRATION CURVE METHOD AND ITS VALIDATION." INDIAN DRUGS 49, no. 07 (2012): 36–41. http://dx.doi.org/10.53879/id.49.07.p0036.

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The proposed UV spectrophotometric method for estimation of acetazolamide is based on the official method for dissolution of acetazolamide tablets mentioned in the United States Pharmacopoeia XXXII. The monograph, however, does not provide basis for estimation of acetazolamide in the bulk drugs by UV spectrophotometric method. Hence a simple, quick and economic method was developed and validated for estimation of acetazolamide in the bulk drug and its dosage forms. This method may be adopted for routine quality control of acetazolamide in bulk drugs and in finished dosage forms.
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Jampilek, Josef, Kamil Zaruba, Michal Oravec, et al. "Preparation of Silica Nanoparticles Loaded with Nootropics and TheirIn VivoPermeation through Blood-Brain Barrier." BioMed Research International 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/812673.

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The blood-brain barrier prevents the passage of many drugs that target the central nervous system. This paper presents the preparation and characterization of silica-based nanocarriers loaded with piracetam, pentoxifylline, and pyridoxine (drugs from the class of nootropics), which are designed to enhance the permeation of the drugs from the circulatory system through the blood-brain barrier. Their permeation was compared with non-nanoparticle drug substances (bulk materials) by means of anin vivomodel of rat brain perfusion. The size and morphology of the nanoparticles were characterized by t
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Li, Wanru. "A Review of Research on China's Centralized Drugs Bulk-buying Platform for Public Welfare." Frontiers in Business, Economics and Management 13, no. 2 (2024): 62–65. http://dx.doi.org/10.54097/k9fr0x86.

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Inflated drug prices have always been a problem in the circulation of medicines in China, and in recent years, the relevant departments in China have formulated a series of policies to control drug prices, one of the strongest and most effective of which is to carry out centralized procurement of medicines. The state has also introduced a series of related policies around the centralized procurement of drugs, including the establishment of a centralized procurement platform for drugs. Therefore, this paper focuses on the concept of centralized drugs bulk-buying platform, the current developmen
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Bunch, Elaine A. "Liquid Chromatographic Determination and Identification Tests for Dexamethasone in Bulk Drugs and Elixirs: Collaborative Study." Journal of AOAC INTERNATIONAL 70, no. 6 (1987): 967–73. http://dx.doi.org/10.1093/jaoac/70.6.967.

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Abstract A normal phase liquid chromatographic method for the determination of dexamethasone in bulk drugs and elixirs was collaboratively studied by 6 laboratories. The method uses a silica column, water-modified acetic acid-methanol-methylene chloride mobile phase, cortisone internal standard, and photometric detection at 254 nm. Collaborators were supplied blind duplicate samples of 3 bulk drugs, 2 commercial elixirs, and 1 authentic elixir. Dexamethasone elixir dosage level is 0.5 mg/5 tnL. Mean recovery of dexamethasone from the authentic elixir formulated to contain 0.471 mg/5 mL was 94.
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Dissertationen zum Thema "Bulk Drug"

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Lewis, Paul O., David B. Cluck, Jessica D. Huffman, Amanda P. Ogle, and Stacy D. Brown. "Stability of a Pyrimethamine Suspension Compounded from Bulk Powder." Digital Commons @ East Tennessee State University, 2017. https://doi.org/10.2146/ajhp160551.

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Purpose:Development of a stability-indicating high-performance liquid chromatography (HPLC) method for pyrimethamine analysis, with subsequent application of that method to assess the 90-day stability of a pyrimethamine suspension compounded from bulk USP-grade pyrimethamine powder, is described. Methods:A stability-indicating method of HPLC with ultraviolet detection specific to pyrimethamine was developed according to pharmacopeial recommendations and validated. The method was applied to investigate the stability of a 2-mg/mL pyrimethamine suspension in a vehicle consisting of Ora-Plus and O
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Tindle, R. "Deliberate crystal habit modification of pharmaceuticals and its effect on bulk and tabletting properties." Thesis, University of Nottingham, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378939.

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Denk, Oliver Matthias. "Impurity studies of bulk drug substances by capillary electrophoresis and high performance liquid chromatography." Thesis, University of Strathclyde, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248566.

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Vukmirovic, Neda. "Drug deposition and distribution in healthy and atherosclerotic arteries and in models of atherosclerosis following bulk or stent-based drug delivery." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/40871.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2007.<br>Includes bibliographical references.<br>Drug eluting stents have revolutionized the practice of medicine and the landscape of medical devices. Yet, more than four years after introduction clinical trial data and clinical use have still not fully clarified what drives the safety and efficacy of these devices. The goal of this thesis was to help fill this void by describing the mechanisms by which stent-eluted drugs are distributed within healthy and atherosclerotic vascular models. In the first part of the thesis
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Jansson, Björn. "Models for the transfer of drugs from the nasal cavity to the central nervous system /." Uppsala : Acta Universitatis Upsaliensis: Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3905.

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Didonet, Juliana. "Avaliação da bula de medicamentos sob a ótica dos idosos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/23919.

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O objetivo deste estudo é avaliar a bula dos medicamentos sob a ótica dos idosos verificando os aspectos da compreensão, visibilidade, legibilidade e as opiniões relacionadas à bula. Foram entrevistadas pessoas que freqüentavam grupos de atividades para idosos, localizados no estado do Rio Grande do Sul. Um total de 88 participantes leu a bula do fármaco atenolol. Destes, um grupo de 47 pessoas leu a bula redigida de acordo com a Portaria nº 110/1997 e outro de 41 pessoas leu a bula do mesmo fármaco redigida de acordo com a RDC nº 140/2003, sendo que após a leitura recebiam um valor de pontuaç
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Abahamye, Aloysius. "Cost comparison between repackaging bulk oral solid medicines and purchasing manufacturer-prepared patient-ready packs in the public sector in South Africa." Thesis, Nelson Mandela Metropolitan University, 2014. http://hdl.handle.net/10948/d1020596.

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In an attempt to have medicines available in patient-ready packs (PRPs) prior to the dispensing process, the provincial medicine depots in South Africa have, for many years, been repackaging bulk medicines into PRPs. Notwithstanding the fact that bulk medicine packages may have been the only packages available from the manufacturers to service the Primary Health Care (PHC) sector, the main aim of this process was to ensure that medicines were available in PRPs for dispensing to patients, thus, minimising the time spent on each prescription by the pharmacist, pharmacist’s assistant or Nurse. Cu
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Dick, Graeme. "Development and use of a discrete element model for simulating the bulk strand flow in a rotary drum blender." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1517.

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In 2006 resin accounted for approximately 17% of the direct manufacturing costs for oriented strand board (OSB). Because of their increased dependency on pMDI-resins, this percentage is likely greater for oriented strand lumber (OSL) and laminated strand lumber (LSL). The cost of PF- and pMDI-resins is expected to face upward pressure as the cost of their primary constituents, natural gas and crude oil, continue to reach new highs. Therefore, there is strong economic incentive to optimize the use of resin in the production of these three products. This can be accomplished by addressing tw
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Silva, João Vitor Ferrari da. "Fácil bula: sistema que estrutura o bulário eletrônico da Anvisa." Universidade Tecnológica Federal do Paraná, 2016. http://repositorio.utfpr.edu.br/jspui/handle/1/2551.

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O trabalho desempenhado pelos profissionais da área de saúde quando voltado ao cuidado das pessoas consiste, por vezes, na escolha dos melhores medicamentos para o sucesso terapêutico no tratamento de pacientes. Existem vários medicamentos disponíveis no mercado brasileiro, assim para que o profissional encontre as informações sobre o medicamento que pode ser melhor indicado para o paciente há aplicativos e ferramentas que facilitam a pesquisa dos medicamentos e auxiliam o trabalho deste especialista. Contudo em nossa busca não foram encontrados sistemas que possuem a identificação de reações
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Bergman, Ulrika. "Transfer and toxicity of some drugs and chemicals in the olfactory mucosa and bulb /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/avh/2000/91-576-5909-5.pdf.

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Bücher zum Thema "Bulk Drug"

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MVIRDC World Trade Centre, Bombay., ed. Globalisation and SMEs: Impact on Indian bulk drug & dyes sectors. Quest Publications, 2002.

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Dalal Consultants and Engineers Limited (Ahmedabad, India). Management Consultancy Division. and MVIRDC World Trade Centre, Bombay., eds. Impact of liberalisation and globalisation on the small & medium enterprises in the bulk drug & dyes sectors. MVIRDC World Trade Centre, 2001.

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United States. Congress. House. Committee on Commerce. Subcommittee on Oversight and Investigations. Counterfeit bulk drugs: Hearings before the Subcommittee on Oversight and Investigations of the Committee on Commerce, House of Representatives, One Hundred Sixth Congress, second session, June 8 and October 3, 2000. U.S. G.P.O., 2000.

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McBurney, Graeme Thomas. Implementation of the American Food and Drug Administration code of federal regulations for pharmaceutical and bulk chemical good manufacturing practice into a pharmaceutical company operating to European Community good pharmaceutical manufacturing practices. The Author], 1994.

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United States. Food and Drug Administration. Division of Field Investigations., ed. Guide to inspections of bulk pharmaceutical chemicals. Division of Field Investigations, Office of Regional Operations, Office of Regulatory Affairs, U.S. Food & Drug Administration, 1994.

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India. Central Pollution Control Board., ed. Guidelines for optimum water consumption in bulk drugs manufacturing industry. Central Pollution Control Board, Ministry of Environment & Forests, 2007.

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Simmons, Paul L. Introduction to good manufacturing practice regulations: Drugs, devices, diagnostics, biotechnology, and bulk pharmaceutical chemicals. International Center for Technology Transfer, 1988.

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Simmons, Paul L. The impact of GMP's on the manufacture of bulk pharmaceutical chemicals/biologics: Drugs, diagnostics, biotechnology. International Center for Technology Transfer, 1988.

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United States. Congress. House. Committee on Commerce. Subcommittee on Oversight and Investigations. Counterfeit bulk drugs: Hearings before ... 106th Congress, 2nd session, June 8 and October 3, 2000. U.S. G.P.O., 2000.

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United States. Congress. House. Committee on Commerce, ed. 106-2 Hearings: Counterfeit Bulk Drugs, Serial No. 106-164, June 8 and October 3, 2000. s.n., 2001.

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Buchteile zum Thema "Bulk Drug"

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Jameel, Feroz, Tong Zhu, and Brittney J. Mills. "Chapter 19: Design of a Bulk Freeze-Thaw Process for Biologics." In Development of Biopharmaceutical Drug-Device Products. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-31415-6_19.

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Suffness, Matthew. "Discovery and Bulk Production of Natural Products with Anticancer Activity: The Role of Chemical Ecology." In Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3492-1_8.

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Musmade, P., N. Vadera, and G. Subramanian. "Stability-Indicating HPTLC Determination of Imatinib Mesylate in Bulk Drug and Pharmaceutical Dosage." In High-Performance Thin-Layer Chromatography (HPTLC). Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-14025-9_6.

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Kumar, Sunil, and Trilochan Mishra. "Organization of Bio-Molecules in Bulk and Over the Nano-Substrate: Perspective to the Molecular Dynamics Simulations." In Biointerface Engineering: Prospects in Medical Diagnostics and Drug Delivery. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4790-4_7.

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Vadthya, Pavani, Pavani Vadthya, Y. V. L. Ravikumar, S. Sridhar, and S. Sridhar. "Reclamation of Water and Toluene from Bulk Drug Industrial Effluent by Vacuum Membrane Distillation." In Membrane Processes. John Wiley & Sons, Inc., 2018. http://dx.doi.org/10.1002/9781119418399.ch16.

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Fruchtbaum, Jacob. "Flight and Drag Conveyors." In Bulk Materials Handling Handbook. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4757-4695-2_6.

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Tang, Weici, and Gerhard Eisenbrand. "Panax notoginseng (Burk.) F. H. Chen." In Chinese Drugs of Plant Origin. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-73739-8_93.

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Sulistyawati, Wiwin, and Purwo Joko Suranto. "The Bulb Concept in Drag Reduction on Pentamaran." In Lecture Notes in Mechanical Engineering. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-0867-5_18.

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Dawson, Valina L., Ted M. Dawson, and James K. Wamsley. "Autoradiographic Localization of Drug and Neurotransmitter Receptors in the Olfactory Bulb." In Molecular Neurobiology of the Olfactory System. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0989-5_5.

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"bulk drug substance." In Dictionary of Pharmaceutical Medicine. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_147.

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Konferenzberichte zum Thema "Bulk Drug"

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Li, Zhaoxin, Changyan He, Akshat Verma, and Eric Diller. "3D Printed Untethered Magnetic Bulb for Liquid Biopsy and Drug Delivery." In 2024 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS). IEEE, 2024. http://dx.doi.org/10.1109/marss61851.2024.10612722.

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Nixon, Randy. "Lessons to Be Learned from Rehabilitation of Concrete Structures in Bleach Plants in Pulp and Paper Mills." In CORROSION 1995. NACE International, 1995. https://doi.org/10.5006/c1995-95645.

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Abstract The deterioration of concrete structures due to chloride induced reinforcing steel corrosion such as in elevated concrete floor slabs, columns, and beams in bleach plants is a constant and growing problem within the pulp and paper industry. In general, the condition analysis methods used for assessing the extent of bleach plant concrete degradation include physical testing of drilled concrete core samples, chloride ion concentration testing, half-cell potential measurements, and physical sounding of concrete surfaces, i.e. chain drag for topside surfaces and hammer sounding of soffit
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Tsuei, Timothy W. "Design and Fabrication of a LIGA-Fabricated Microvalve for Drug Delivery Applications." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-1286.

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Abstract In this paper, we will describe the design and development of a normally closed, low power microvalve for drug delivery applications. This microvalve is fabricated using a modified LIGA technique. Multiple, precision, off-axis X-ray exposures of PMMA resist are used to define a tapered valve seat and plunger. The final valve assembly consists of hybrid components of a bulk micromachined Si membrane, conventionally machined channels and LIGA-defined valve seats and plungers. An external micro electromagnet was used to control plunger displacement, thereby providing flow control. Total
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Vazquez, Louis C., Erik Hagel, Bradley J. Willenberg, Christopher D. Batich, and Malisa Sarntinoranont. "Effect of Polymer Coated Needles on Infusate Backflow During Convection-Enhanced Delivery." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19557.

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Currently, many central nervous system disorders cannot be treated effectively using conventional drug delivery methods such as oral and intravenous drug administration. Therapeutic agents for such disorders often contain polar proteins with high molecular weight compounds (i.e. enzymes, antibodies and gene vectors) that are too large to diffuse through the tight junctions of the blood brain barrier (BBB) [1]. Moreover, it has been shown that low molecular weight compounds, though highly diffusive within brain tissue and tumors, have a limited distribution of just a few millimeters from the si
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Soares, João A., and Paolo Zunino. "A Multiscale Mixture Model for Polymer Degradation and Erosion." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19251.

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Over the last 50 years, biodegradable materials have found a wide variety of applications in the medical field ranging from biodegradable sutures, pins and screws for orthopedic surgery, implants for local drug delivery, tissue engineering scaffolds, and biodegradable endovascular and urethral stents. The ability to predict the evolution of biodegradable polymers over the course of degradation would enhance the biodegradable implant design process. Polymer degradation is the irreversible chain scission process that breaks polymer chains down to oligomers and finally monomers. Extensive degrada
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Xue, Jia, Wubin Qian, Sheng Guo, Xiaoyu An, Xuesong Ouyang, and Henry Q. Li. "Abstract 1016: Transcriptomic analysis of bulk tissues of large PDX collection as a novel platform discovering new TME target/drug." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1016.

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Valentin, Francisco I., and Silvina Cancelos. "Detecting Presence of Bubbles Within Simulated Blood Vessels Using a Piezoelectric Ring Set to Oscillate at Matching Resonant Conditions." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80822.

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A variety of methods have been used to detect and measure the presence and size of bubbles that occur naturally in tubes or blood vessels. These traits have recently produced interest in biomedical fields including drug delivery systems and decompression sickness, among others. To detect and measure bubbles, optical, acoustic, and equivalent bulk properties methods have primarily been used; each exploiting unique characteristics of bubbles [1]. Among these, Doppler techniques based on the backscattering of ultrasound waves, have been used to detect and measure bubbles within fluid media [2,3].
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Bonfiglio, Andrea, Alessandro Stocchino, Rodolfo Repetto, and Jennifer H. Siggers. "In-Vitro Simulations of Drug Delivery in the Vitreous Chamber of the Eye." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80272.

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The vitreous chamber has an approximately spherical shape, and is filled with vitreous humor, a transparent material with viscoelastic properties. The vitreous humor has the mechanical roles of supporting the eye shape, promoting the adherence between the retina and the choroid, and acting as a barrier between the anterior and posterior segments of the eye for transport of heat and molecules [1]. Often, in elderly people, the vitreous humor has almost Newtonian properties as a consequence of a liquefaction process consisting of degradation of the collagenous framework of the gel. Moreover, aft
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Zhang, Haipeng, Aidan Johnson, Sangjin Ryu, Seunghee Kim, and Chi (Kevin) Zhang. "Fabrication of Heterogeneous Hydrogel Models for Convection-Enhanced Drug Delivery Studies." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-67615.

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Abstract Convection-enhanced drug delivery (CED) enables faster convective dispersion of drug molecules through soft, porous tissues than diffusion, which is beneficial for treating aggressive tumors. Advancing the CED technology requires rigorous characterization of fluid transport through soft, porous tissues. When a fluid flows through soft, porous tissues, the deformation and/or structural rearrangement of the hosting solid alters the pattern and efficiency of fluid propagation. Such hydro-mechanical coupling can be understood by experimentally studying fluid flows through hydrogel phantom
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Brown, Paige K., Ammar T. Qureshi, Daniel J. Hayes, and W. Todd Monroe. "Targeted Gene Silencing With Light and a Silver Nanoparticle Antisense Delivery System." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53647.

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Targeted delivery and controlled release of oligonucleotide therapeutics in vivo are essential aspects of an ideal delivery vehicle. Here we demonstrate the synthesis and in vitro/intracellular characterization of silver nanoparticle (SNP) photolabile nucleic acid conjugates, with the aim of developing a nanoparticulate platform for inducible gene silencing. Due to unique size related properties, nanostructures are being increasingly utilized for intracellular diagnostics and delivery applications. While most nanoscale delivery platforms are polymeric in composition, studies of metallic nanopa
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Berichte der Organisationen zum Thema "Bulk Drug"

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Novotny, Jaroslav F. Preparation of Bulk Drug for the U.S. Army Drug Development Program. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada425622.

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Novotny, Jaroslav. Preparation of Bulk Drug for the U.S. Army Drug Development Program. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada392524.

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Lim, Peter. Analytical, Characterization and Stability Studies of Chemicals, Bulk Drugs and Drug Formulations. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/adb233658.

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Novotny, Jaroslav. Preparation of Chemicals and Bulk Drug Substance for the U.S. Army Drug Development Program. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada382468.

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Novotny, Jaroslav F. Preparation of Chemicals and Bulk Drug Substances for the U.S. Army Drug Development Program. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/adb232976.

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Kupina, Steve, Mark Kelm, Maria Monagas, and STEFAN GAFNER. Grape Seed Extract Laboratory Guidance Document. ABC-AHP-NCNPR Botanical Adulterants Prevention Program, 2019. http://dx.doi.org/10.59520/bapp.lgd/dozo2637.

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Grape Seed Extract (GSE) has received acceptance almost globally as an ingredient for human consumption. It is one of the more widely used botanical extracts, due to increasing scientific findings supporting health benefits. However, it remains a specialty item relative to global commodities. In the United States, GSE has ranked among the top 20 best-selling dietary supplements in the Food, Drug and Mass Market channel. The motivation behind purposeful adulteration in commercial products is financial gain (also known as economically motivated adulteration) and to increase the concentration in
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Najafi, Nezam. Performance Oriented Packaging Testing of Bulk Propellant in New Fiber Drum. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada211199.

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Pullammanappallil, Pratap, Haim Kalman, and Jennifer Curtis. Investigation of particulate flow behavior in a continuous, high solids, leach-bed biogasification system. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7600038.bard.

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Recent concerns regarding global warming and energy security have accelerated research and developmental efforts to produce biofuels from agricultural and forestry residues, and energy crops. Anaerobic digestion is a promising process for producing biogas-biofuel from biomass feedstocks. However, there is a need for new reactor designs and operating considerations to process fibrous biomass feedstocks. In this research project, the multiphase flow behavior of biomass particles was investigated. The objective was accomplished through both simulation and experimentation. The simulations included
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