Auswahl der wissenschaftlichen Literatur zum Thema „C-myc gene“

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Zeitschriftenartikel zum Thema "C-myc gene"

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Zobel, Andrea, Frank Kalkbrenner, Gerd Vorbrueggen, and Karin Moelling. "Transactivation of the human c-myc gene by c-Myb." Biochemical and Biophysical Research Communications 186, no. 2 (1992): 715–22. http://dx.doi.org/10.1016/0006-291x(92)90805-u.

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Evans, J. L., T. L. Moore, W. M. Kuehl, T. Bender, and J. P. Ting. "Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter." Molecular and Cellular Biology 10, no. 11 (1990): 5747–52. http://dx.doi.org/10.1128/mcb.10.11.5747.

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The function of c-Myb protein was revealed by transfecting an expression vector containing the entire c-Myb protein-coding sequence into the murine CTLL-2 T-cell line. Expressions of high levels of c-Myb protein did not alter the expression of several T-cell markers, c-fos mRNA expression, responses to interleukin-2, and growth characteristics of these cells. Interestingly, expression of the c-myc gene was drastically increased in this clone. Further, the c-myb expression plasmid, but not a frameshift mutant of c-myb, enhanced the expression of a hybrid construct of c-myc promoter linked to a
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Evans, J. L., T. L. Moore, W. M. Kuehl, T. Bender, and J. P. Ting. "Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter." Molecular and Cellular Biology 10, no. 11 (1990): 5747–52. http://dx.doi.org/10.1128/mcb.10.11.5747-5752.1990.

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The function of c-Myb protein was revealed by transfecting an expression vector containing the entire c-Myb protein-coding sequence into the murine CTLL-2 T-cell line. Expressions of high levels of c-Myb protein did not alter the expression of several T-cell markers, c-fos mRNA expression, responses to interleukin-2, and growth characteristics of these cells. Interestingly, expression of the c-myc gene was drastically increased in this clone. Further, the c-myb expression plasmid, but not a frameshift mutant of c-myb, enhanced the expression of a hybrid construct of c-myc promoter linked to a
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Cogswell, J. P., P. C. Cogswell, W. M. Kuehl, et al. "Mechanism of c-myc regulation by c-Myb in different cell lineages." Molecular and Cellular Biology 13, no. 5 (1993): 2858–69. http://dx.doi.org/10.1128/mcb.13.5.2858.

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Activation of the murine c-myc promoter by murine c-Myb protein was examined in several cell lines by using a transient expression system in which Myb expression vectors activate the c-myc promoter linked to a chloramphenicol acetyltransferase reporter gene or a genomic beta-globin gene. S1 nuclease protection analyses confirmed that the induction of c-myc by c-Myb was transcriptional and affected both P1 and P2 start sites in a murine T-cell line, EL4, and a myelomonocytic line, WEHI-3. Mutational analyses of the c-myc promoter revealed that two distinct regions could confer Myb responsivenes
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Cogswell, J. P., P. C. Cogswell, W. M. Kuehl, et al. "Mechanism of c-myc regulation by c-Myb in different cell lineages." Molecular and Cellular Biology 13, no. 5 (1993): 2858–69. http://dx.doi.org/10.1128/mcb.13.5.2858-2869.1993.

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Activation of the murine c-myc promoter by murine c-Myb protein was examined in several cell lines by using a transient expression system in which Myb expression vectors activate the c-myc promoter linked to a chloramphenicol acetyltransferase reporter gene or a genomic beta-globin gene. S1 nuclease protection analyses confirmed that the induction of c-myc by c-Myb was transcriptional and affected both P1 and P2 start sites in a murine T-cell line, EL4, and a myelomonocytic line, WEHI-3. Mutational analyses of the c-myc promoter revealed that two distinct regions could confer Myb responsivenes
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Arsura, Marcello, Claudia S. Hofmann, Josee Golay, Martino Introna, and Gail E. Sonenshein. "A-myb rescues murine B-cell lymphomas from IgM-receptor–mediated apoptosis through c-myctranscriptional regulation." Blood 96, no. 3 (2000): 1013–20. http://dx.doi.org/10.1182/blood.v96.3.1013.

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Abstract A-myb is a member of the myb family of transcription factors, which regulates proliferation, differentiation, and apoptosis of hematopoietic cells. A-Myb expression is normally restricted to the proliferating B-cell centroblasts and transgenic mice overexpressing A-myb displayed enhanced hyperplasia of the lymph nodes. Because A-Myb is highly expressed in several subtypes of human B-cell neoplasias, we sought to determine whether the A-myb gene promoted proliferation and survival of B lymphocytes, using the WEHI 231 and CH33 murine B-cell lymphomas as models. Here, we show that ectopi
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Arsura, Marcello, Claudia S. Hofmann, Josee Golay, Martino Introna, and Gail E. Sonenshein. "A-myb rescues murine B-cell lymphomas from IgM-receptor–mediated apoptosis through c-myctranscriptional regulation." Blood 96, no. 3 (2000): 1013–20. http://dx.doi.org/10.1182/blood.v96.3.1013.015k06_1013_1020.

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A-myb is a member of the myb family of transcription factors, which regulates proliferation, differentiation, and apoptosis of hematopoietic cells. A-Myb expression is normally restricted to the proliferating B-cell centroblasts and transgenic mice overexpressing A-myb displayed enhanced hyperplasia of the lymph nodes. Because A-Myb is highly expressed in several subtypes of human B-cell neoplasias, we sought to determine whether the A-myb gene promoted proliferation and survival of B lymphocytes, using the WEHI 231 and CH33 murine B-cell lymphomas as models. Here, we show that ectopic express
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Woloschak, M., J. L. Roberts, and K. Post. "c-myc, c-fos, and c-myb gene expression in human pituitary adenomas." Journal of Clinical Endocrinology & Metabolism 79, no. 1 (1994): 253–57. http://dx.doi.org/10.1210/jcem.79.1.8027238.

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Woloschak, M. "c-myc, c-fos, and c-myb gene expression in human pituitary adenomas." Journal of Clinical Endocrinology & Metabolism 79, no. 1 (1994): 253–57. http://dx.doi.org/10.1210/jc.79.1.253.

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Mestdagh, P., E. Fredlund, F. Pattyn, et al. "MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors." Oncogene 29, no. 9 (2009): 1394–404. http://dx.doi.org/10.1038/onc.2009.429.

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Dissertationen zum Thema "C-myc gene"

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Straaten, J. P. van. "Studies on the human c-myc gene product." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377708.

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Kuschak, Theodore I. "c-Myc dependent genomic instability of the ribonucleotide reductase R2 gene." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0020/NQ53061.pdf.

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Chana, Jagdeep. "The prognostic and therapeutic significance of C-MYC expression in melanoma." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314348.

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Melkoumian, Zaroui K. "Pharmacological regulation of c-myc gene expression in human breast cancer cells." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2218.

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Thesis (Ph. D.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains x, 152 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 119-149).
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Dedieu, Jean-François. "Activites et localisation du produit du premier exon de l'oncogene c-myc humain." Paris 6, 1987. http://www.theses.fr/1987PA066331.

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Peres, Raquel Mary Rodrigues 1983. "Instabilidade genômica em neoplasias malignas da mama em função da concentração de alumínio intracelular : Genomic instability association with intracellular aluminum concentration in breast tumors." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310522.

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Orientador: Luis Otavio Zanatta Sarian<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-11-07T13:37:40Z (GMT). No. of bitstreams: 1 Peres_RaquelMaryRodrigues_D.pdf: 3497486 bytes, checksum: c509c5d08807f1a5bcd1b918eaf7d09d (MD5) Previous issue date: 2013<br>Resumo: Introdução: A hipótese de que os efeitos do alumínio em células humanas podem ter implicações clínicas tem sido levantada há algum tempo, especialmente no que concerne ao câncer de mama. As evidências laboratoriais mostrando altos níveis de alumínio nos teci
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Lepique, Ana Paula. "O Gene c-myc e o controle do ciclo celular por ACTH em células adrenocorticais de camundongo da linhagem Y-1." Universidade de São Paulo, 2000. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-14102008-085011/.

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ACTH é o hormônio trófico que estimula a esteroidogênese, promove o crescimento e a manutenção do córtex adrenal. Porém, em linhagens adrenocorticais, assim como em culturas primárias, ACTH inibe a proliferação celular. A linhagem Y-1 de células adrenocorticais de camundongo tem as seguintes respostas a ACTH: aumento da esteroidogênese, arredondamento celular, bloqueio do ciclo celular em G1 e indução dos proto-oncogenes fos e jun. Esta linhagem também responde muito Sem a FGF2, um protótipo da família dos FGFs (Fibroblast Growth Factors) que regula diferenciação e proliferação de diversos tip
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Hagemeier, Christian. "Transactivation of the hsp70 gene and protooncogenes c-fos and c-myc by human cytomegalovirus immediate early proteins." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316643.

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Clarke, Matthew Alan. "Predictive computational modelling of the c-myc gene regulatory network for combinatorial treatments of breast cancer." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/284163.

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As cancer tumours develop, competition between cells will favour those with some mutations over others, creating a dynamic heterogeneous system made up of different cell populations, called sub-clones. This heterogeneity poses a challenge for treatment, as this variety serves to ensure there is almost always a portion of the cells which are resistant to any one targeted therapy. This can be avoided by combining therapies, but finding viable combinations experimentally is expensive and time-consuming. However, there is also cooperation between sub-clones, and being able to better model and pred
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SILVA, FILHO João Luiz Quirino da. "Avaliação da amplificação e superexpressão do gene c-myc em subtipos moleculares de carcinoma ductal invasivo." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/23420.

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Submitted by Rafael Santana (rafael.silvasantana@ufpe.br) on 2018-01-30T17:59:42Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Versão Final-TESE-EICB-10-02-2017.pdf: 2121418 bytes, checksum: ad23456aec856da13a2581e107c840e7 (MD5)<br>Made available in DSpace on 2018-01-30T17:59:42Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Versão Final-TESE-EICB-10-02-2017.pdf: 2121418 bytes, checksum: ad23456aec856da13a2581e107c840e7 (MD5) Previous issue date: 2016-03-30<br>REUNI<br>O câncer de m
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Bücher zum Thema "C-myc gene"

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Potter, M. C-myc In B-cell Neoplasia: 14TH WORKSHOP ON MECHANISMS IN B-CELL NEOPLASIA (Current Topics in Microbiology & Immunology). Edited by M. Potter. SPRINGER-VERLAG, 1997.

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Buchteile zum Thema "C-myc gene"

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Jackstadt, Rene, Antje Menssen, and Heiko Hermeking. "Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs, and c-MYC DNA Binding by Next-Generation Sequencing." In The Myc Gene. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-429-6_11.

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Jackstadt, Rene, Markus Kaller, Antje Menssen, and Heiko Hermeking. "Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing." In The Myc Gene. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1476-1_7.

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Dang, Chi V., and Linda A. Lee. "Historical Perspectives of myc Gene Studies." In c-Myc Function in Neoplasia. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22681-0_3.

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Daniel, Colin J., Xiaoli Zhang, and Rosalie C. Sears. "Detection of c-Myc Protein–Protein Interactions and Phosphorylation Status by Immunoprecipitation." In The Myc Gene. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-429-6_5.

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Zinzalla, Giovanna. "Biophysical and Structural Methods to Study the bHLHZip Region of Human c-MYC." In The Myc Gene. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1476-1_3.

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Dang, Chi V., and Linda A. Lee. "Structure of the c-myc Gene and its Transcription." In c-Myc Function in Neoplasia. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22681-0_4.

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To, Kenneth K. W., and L. Eric Huang. "An Efficient Way of Studying Protein–Protein Interactions Involving HIF-α, c-Myc, and Sp1." In The Myc Gene. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-429-6_6.

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Delattre, Patrick, Martin Montagne, and Pierre Lavigne. "Methods of Expression, Purification, and Preparation of the c-Myc b-HLH-LZ for Its Biophysical Characterization." In The Myc Gene. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1476-1_2.

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Todorović-Raković, Nataša. "Detection of c-myc Amplification in Formalin-Fixed Paraffin-Embedded Tumor Tissue by Chromogenic In Situ Hybridization (CISH)." In The Myc Gene. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-429-6_17.

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Bello-Fernandez, C., and J. L. Cleveland. "c-myc Transactivates the Ornithine Decarboxylase Gene." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77633-5_56.

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Konferenzberichte zum Thema "C-myc gene"

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Rezzoug, Francine, Shelia D. Thomas, Segen Tella, and Donald M. Miller. "Abstract 1522: Targeted gene therapy · c-MYC and hTERT in the scope." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1522.

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Yim, Christina Y., David J. Sekula, Sarah J. Freemantle, Ethan Dmitrovsky, and Michael J. Spinella. "Abstract 2026: G0S2 functions as a tumor suppressor gene through inhibition of c-Myc." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2026.

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Birkeland, Even, Antje Krohn, Jone Trovik, et al. "Abstract 331: C-MYC gene amplification in endometrial cancer is associated with aggressive tumors." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-331.

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Stur, Elaine, Shelia Thomas, Francine Rezzoug, and Donald Miller. "Abstract 1520: Down-regulation of c-MYC and hTERT gene expression in triple negative breast cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1520.

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Tao, Yongguang, Shuang Liu, and Yiqun Jiang. "Abstract 4317: EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4317.

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Elvin, Paul, Neil Pegg, Simone Daminelli, et al. "Abstract 1019: P300/CBP inhibitor CCS1477 targets 22Rv1 prostate tumor AR and c-myc gene expressionin vivo." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1019.

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Elvin, Paul, Neil Pegg, Simone Daminelli, et al. "Abstract 1019: P300/CBP inhibitor CCS1477 targets 22Rv1 prostate tumor AR and c-myc gene expressionin vivo." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1019.

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Farrell, Amy, Carl Pelz, Xiaoyan Wang, et al. "Abstract 771: Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-771.

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Komiya, Kazutoshi, Naoko Sueoka-Aragane, Akemi Sato, et al. "Abstract 4650: A novel c-Myc target gene, Mina53, is a favorable prognostic marker in early stage of lung cancer." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4650.

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Baykara, Onur, Elif Baltaci, Betul Seyhan, Nejat Dalay, and Nur Buyru. "Abstract 1132: Regulation of CT120 gene as a new target of c-myc in head and neck squamous cell carcinoma (HNSCC)." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1132.

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Berichte der Organisationen zum Thema "C-myc gene"

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Sheen, Joon-Ho. A Gene Amplification Phenotype in c-Myc-Induced Mammary Tumors Cells. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada396567.

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Sheen, Joon-Ho. A Gene Amplification Phenotype in c-Myc-Induced Mammary Tumors Cells. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada390716.

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Melkoumian, Zaroui. Regulation of C-myc Gene Expression by Potassium Channel Blocker Quindine in MCF-7 Human Breast Cancer Cell Line. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada384096.

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Ye, Shanli. DNA Sequences Involved in the Regulation of Human c-myc Gene Expression by Herpes Simplex Virus Type 1 (HSV-1). Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.7097.

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