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1

Ashidi, Joseph S., Irene E. Emeya, Folarin O. Owagboriaye, Roseline T. Feyisola, Olubukola I. Lawal, and Olaitan C. Okechukwu. "Neurological behaviour of albino rats treated separately and in combination with Cannabis sativa L. and Cannabis indica L." Scientia Africana 20, no. 2 (2021): 37–50. http://dx.doi.org/10.4314/sa.v20i2.4.

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There has been an increasing rate of cannabis consumption globally, especially among the youths. This study therefore evaluated the neurological behaviours and some brain marker hormones and enzymes of cannabis administered rats. Twenty six albino rats were divided into four groups based on oral cannabis administration (control, Cannabis sativa, Cannabis indica and the combination of the two). At the end of seven days, open field test was conducted on the rats. Also, brain neuro-chemicals, activities of antioxidant enzymes and lipid peroxidation were evaluated using spectrophotometry. The resu
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Shin, Joonyoung, Sangheon Choi, A. Yeong Park, et al. "In Vitro and In Vivo Anti-Inflammatory and Antidepressant-like Effects of Cannabis sativa L. Extracts." Plants 13, no. 12 (2024): 1619. http://dx.doi.org/10.3390/plants13121619.

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Cannabis sativa L. has been widely used by humans for centuries for various purposes, such as industrial, ceremonial, medicinal, and food. The bioactive components of Cannabis sativa L. can be classified into two main groups: cannabinoids and terpenes. These bioactive components of Cannabis sativa L. leaf and inflorescence extracts were analyzed. Mice were systemically administered 30 mg/kg of Cannabis sativa L. leaf extract 1 h before lipopolysaccharide (LPS) administration, and behavioral tests were performed. We conducted an investigation into the oxygen saturation, oxygen tension, and degr
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Ravindra B. Malabadi, Kiran P. Kolkar, Raju K. Chalannavar, and Himansu Baijnath. "Cannabis sativa: Difference between Medical Cannabis (Maijuana or drug type) and Industrial hemp." GSC Biological and Pharmaceutical Sciences 24, no. 3 (2023): 377–81. http://dx.doi.org/10.30574/gscbps.2023.24.3.0393.

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This paper reviewed the importance of Cannabis sativa and highlights difference between Medical Cannabis (Maijuana or drug type) and Industrial hemp. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes. Industrial hemp and marijuana share the same species, Cannabis sativa L, but represent different varieties. As such, there are genetic differences that lead to different chemical characteristics, which, in turn, lead to different uses. Cannabis sativa L., is classified into two types as Industrial Cannabis sativa, hemp or Medical Cannabis sativa L.(d
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Ouhtit, R., S. Banni, E. Murru, Z. Lamrani, A. Ouhtit, and A. Merzouki. "Assessment of N-Acylethanolamines levels in dry achenes from four cultivars of cannabis sativa L." Grasas y Aceites 75, no. 4 (2024): 2049. https://doi.org/10.3989/gya.1200232.2049.

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We utilized high-performance liquid chromatography-mass spectrometry (HPLC-MS/MS), on dry achenes from four cultivars of Cannabis Sativa L.; CA, Cannabis Sativa L. Cultivar Amnesia; CB, Cannabis Sativa L. Cultivar Beldia; CM, Cannabis Sativa L. Cultivar Mexicana; CK, Cannabis Sativa L. Cultivar Khardala, to detect and quantify N-acylethanolamines (NAEs), which are bioactive compounds involved in lipid and energy metabolism. These plants were grown in Chefchaouen, northern Morocco. All four varieties displayed identical NAE lipid profiles, dominated by those derived from 16C and 18C fatty acids
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Ravindra, B. Malabadi, P. Kolkar Kiran, K. Chalannavar Raju, and Baijnath Himansu. "Cannabis sativa: Difference between Medical Cannabis (Marijuana or drug type) and Industrial hemp." GSC Biological and Pharmaceutical Sciences 24, no. 3 (2023): 377–81. https://doi.org/10.5281/zenodo.10494763.

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This paper reviewed the importance of&nbsp;<em>Cannabis sativa</em>&nbsp;and highlights difference between Medical Cannabis (Marijuana&nbsp;or drug type) and Industrial hemp. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes. Industrial hemp and marijuana share the same species,&nbsp;<em>Cannabis sativa&nbsp;</em>L, but represent different varieties. As such, there are genetic differences that lead to different chemical characteristics, which, in turn, lead to different uses.&nbsp;<em>Cannabis sativa&nbsp;</em>L., is classified into two types as I
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Saxena, Anjani, and Nitin Puranik. "Phytochemistry and Antiperoxidative Potential of Cannabis sativa L. Leaves Methanol Extracts: An In Vitro Study." Journal of Drug Delivery and Therapeutics 13, no. 8 (2023): 110–16. http://dx.doi.org/10.22270/jddt.v13i8.6176.

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Aim: Present study aimed to demonstrate the preliminary phytochemical composition, antioxidant and in vitro protective potential of the methanolic extract of Cannabis sativa L.&#x0D; Study Design: A methanolic extract of Cannabis sativa L. leaves was prepared and assessed at the in vitro level for its preliminary phytochemical screening and antiperoxidative potentials by using the DPPH radical reduction assay, lipid peroxidation inhibitory activity, protein carbonyl inhibitory potential in glycated bovine serum albumin, and enzyme antioxidant activity in a goat liver homogenate system exposed
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Choudhary, S., Shriya, P. Chauhan, et al. "Herbicidal effects of Withania somnifera L. leaf extract on Cannabis sativa L., Hordeum vulgare L. and Cicer arietinum." Allelopathy Journal 53, no. 1 (2021): 69–82. http://dx.doi.org/10.26651/allelo.j/2021-53-1-1328.

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We identified the phytochemicals in Withania somnifera L, a multipurpose medicinal plant of the Himalayan región using TLC, FTIR and HPLC. Eleven formulations were made by mixing in different ratios of Withania leaf extract, wood ash and distilled wáter. Wood chips and twigs of 3-years old Pinus roxburghii tree were completely burnt till ashes was used as Wood ash. The 11-formulationss were i.e. formulation I (Withania leaf extract 100%)), formulation II (75:25 concentration (Withania leaf extract: Distilled water)), formulation III (50:50 concentration (Withania leaf extract: Distilled water)
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Machel, A. EMANUEL, V. HENRY Valrick, and E. ROBINSON Dwight. "Vegetative growth of Cannabis sativa L. cultivars in Jamaica using 18/6 photoperiod." International Journal of Plant Science and Horticulture 2, no. 2 (2020): 56–64. https://doi.org/10.36811/ijpsh.2020.110024.

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Geographic isolation coupled with human selection of Cannabis sativa L. has given rise to the subspecies Cannabis sativa L. subspecies sativa and indica. Plant breeders have cross-pollinated the two subspecies sativa and indica which are considered to be Cannabis hybrids. The therapeutic and medical values of these subspecies are distinct in their applications for a cannabis consumer. The photo sensitive nature of cannabis allows for the manipulation of extending the vegetative cycle for cannabis cultivars that are not native to an equatorial climate. With the use of supplemental lighting to a
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Chacon, Francisco T., Wesley M. Raup-Konsavage, Kent E. Vrana, and Joshua J. Kellogg. "Secondary Terpenes in Cannabis sativa L.: Synthesis and Synergy." Biomedicines 10, no. 12 (2022): 3142. http://dx.doi.org/10.3390/biomedicines10123142.

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Cannabis is a complex biosynthetic plant, with a long history of medicinal use. While cannabinoids have received the majority of the attention for their psychoactive and pharmacological activities, cannabis produces a diverse array of phytochemicals, such as terpenes. These compounds are known to play a role in the aroma and flavor of cannabis but are potent biologically active molecules that exert effects on infectious as well as chronic diseases. Furthermore, terpenes have the potential to play important roles, such as synergistic and/or entourage compounds that modulate the activity of the
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Thomas, Fabian Johannes, and Oliver Kayser. "Minor Cannabinoids of Cannabis sativa L." Journal of Medical Science 88, no. 3 (2019): 141–49. http://dx.doi.org/10.20883/jms.367.

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Cannabinoids from Cannabis sativa L. play an important role as natural products in clinics. The major cannabinoids compromise tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) and its decarboxylated analogs. In this review, we focus on often neglected minor cannabinoids and discuss biosynthetic and chemical degradation routes to other neglected cannabinoids in Cannabis sativa starting from THCA, CBDA and cannabichromenic acid (CBCA). Based on the literature, patents and scientific reports, essential routes for the chemical modification of cannabinoids are discussed to explain ch
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Merzouki, A., F. Ed-derfoufi, and J. Molero Mesa. "Hemp (Cannabis sativa L.) and abortion." Journal of Ethnopharmacology 73, no. 3 (2000): 501–3. http://dx.doi.org/10.1016/s0378-8741(00)00323-8.

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Stephen, Conor, Victor A. Zayas, Andrei Galic, and Mark P. Bridgen. "Micropropagation of Hemp (Cannabis sativa L.)." HortScience 58, no. 3 (2023): 307–16. http://dx.doi.org/10.21273/hortsci16969-22.

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Hemp (Cannabis sativa L.) is commonly grown for the medicinal secondary metabolites produced by pistillate inflorescences. Micropropagation is a valuable method of propagating hemp plants because of the aseptic process and the production of true-to-type propagules. The hemp cultivar TJ’s CBD was used for a series of experiments to compare media inputs and practices for the clonal micropropagation of hemp. For stage I, shoot tips harvested from stock plants that were grown in a growth chamber produced less endogenous contamination in newly established cultures than shoot tips harvested from the
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Fernandes Ramos, Mariana, Chad A. Kinney, Bruna Tassi Borille, et al. "Integrative Review on Cannabis sativa L. Origin Traceability." Brazilian Journal of Forensic Sciences, Medical Law and Bioethics 10, no. 3 (2021): 459–72. http://dx.doi.org/10.17063/bjfs10(3)y2021459-472.

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Marijuana, dried and ground Cannabis, is the most consumed illicit drug in the world. Many undesirable and risky effects to human health are caused by its use. As Cannabis derived drugs and products gain popularity across the world, there has been more and more reports on mislabeled cannabinoid content of Cannabis plants, concentrates and edibles, as well as the number of health issues and deaths caused by their use. In spite of that, many countries have been making their laws more flexible as to marijuana purchase, sale, possession and consumption. Therefore, the development of methodologies
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Borgonetti, Vittoria, Paolo Governa, Monica Montopoli, and Marco Biagi. "Cannabis sativa L. Constituents and Their Role in Neuroinflammation." Current Bioactive Compounds 15, no. 2 (2019): 147–58. http://dx.doi.org/10.2174/1573407214666180703130525.

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The interest in Cannabis sativa L. phytocomplex as a medicinal tool is a recently-emerging topic. Neurodegenerative diseases represent a promising field of application for cannabis and its preparations, as most of this pathologic conditions relies on an inflammatory etiology. Several cannabis constituents display anti-inflammatory effects targeting multiple pathways. In this review, a comprehensive overview of the available literature on C. sativa constituents activities in neuroinflammation is given. On the basis that the anti-inflammatory activity of cannabis is not attributable to only a si
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DUDA, Marcel Matei, Adriana DAN, and Cristina MOLDOVAN. "MEDICINAL AND THERAPEUTIC USES OF CANNABIS SATIVA L." Hop and Medicinal Plants 20, no. 1-2 (2014): 87–89. https://doi.org/10.15835/hpm.v20i1-2.10062.

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The Cannabis plant has a long history of use as medicine, with historical evidence dating back to 2737 BCE (Mohamed Ben Amar, 2006). Cannabis is one of the 50 "fundamental" herbs of traditional Chinese medicine (Wong, Ming, 1976), and is prescribed to for a broad range of indications. Medical cannabis is illegal in most countries. A number of governments, including the U.S. Federal Government, allow treatment with one or more specific low doses of synthetic cannabinoids for one or more disorders.
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Sudhanshu Kumar Jha, Chandan Kumar, Soumya Bharadwaj, et al. "Synthesis, in-silico design and spectral characterization, elucidation of Cannabis sativa L. cannabaceae containing phytoconstitutents demonstrating novel therapeutic efficacy against epilepsy." World Journal of Advanced Research and Reviews 18, no. 2 (2023): 1280–93. http://dx.doi.org/10.30574/wjarr.2023.18.2.0968.

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Cannabis sativa L. is a significant herbaceous species native to Central Asia that has been utilised for folk medicine and other industrial applications. It is a rich source of cellulosic and woody fibres as well as a treasure trove of phytochemicals. The pharmaceutical and construction industries are both very interested in this plant since its metabolites have powerful bioactivities on humans. Cannabinoids are the most researched class of chemicals, primarily because of the vast range of pharmacological effects they have on humans, including psychoactive effects. The phytoconstituents Apigen
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Reznichenko, Irina, and Tatyana Miroshina. "POTENTIAL OF PHYTOCHEMICALS CANNABIS SATIVA L. IN THE FOOD INDUSTRY." Bulletin of KSAU, no. 9 (January 30, 2025): 199–206. https://doi.org/10.36718/1819-4036-2023-9-199-206.

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The purpose of the study is to summarize scientific data to substantiate the use of processed products of Cannabis sativa L. as potential sources of biologically active substances in functional and specialized food systems. Objectives: to analyze hemp phytochemicals, characterize proteins, fats, vitamins and minerals of hemp processing products; to show the effectiveness of using hemp products in medicine in the treatment and prevention of diseases; to assess the possibility of the biopotential of hemp processing products as promising raw materials in functional product technologies. The novel
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Sun, Xiangping. "Research Progress on Cannabinoids in Cannabis (Cannabis sativa L.) in China." Molecules 28, no. 9 (2023): 3806. http://dx.doi.org/10.3390/molecules28093806.

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Cannabis (Cannabis sativa L.) is an ancient cultivated plant that contains less than 0.3% tetrahydrocannabinol (THC). It is widely utilized at home and abroad and is an economic crop with great development and utilization value. There are 31 countries legalizing industrial cannabis cultivation. Cannabis fiber has been used for textile production in China for 6000 years. China is the largest producer and exporter of cannabis. China may still play a leading role in the production of cannabis fiber. China has a long history of cannabis cultivation and rich germplasm resources. Yunnan, Heilongjian
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Naujokienė, Vilma, Kristina Lekavičienė, Eimantas Eigirdas, and Egidijus Šarauskis. "Shredding Roller Effect on the Cannabis sativa L. Residues and Environmental." Processes 11, no. 4 (2023): 1067. http://dx.doi.org/10.3390/pr11041067.

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Fiber cannabis has been grown in Lithuania for a long time, but its cultivation technologies have not been widely studied. However, the growing population and consumption forces us to look to alternatives and to make efforts and find solutions to facilitate the cultivation of fiber cannabis because the use of fiber cannabis can be for many different types of products. The aim of the study was to evaluate the impact of the interaction of fibrous cannabis (Cannabis sativa L.) residue and soil on the mechanical properties of the residue and the environment in cultivation technology using a shredd
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Sudhanshu, Kumar Jha, Kumar Chandan, Bharadwaj Soumya, et al. "Synthesis, in-silico design and spectral characterization, elucidation of Cannabis sativa L. cannabaceae containing phytoconstitutents demonstrating novel therapeutic efficacy against epilepsy." World Journal of Advanced Research and Reviews 18, no. 2 (2023): 1280–93. https://doi.org/10.5281/zenodo.8414284.

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<em>Cannabis sativa L.</em>&nbsp;is a significant herbaceous species native to Central Asia that has been utilised for folk medicine and other industrial applications. It is a rich source of cellulosic and woody fibres as well as a treasure trove of phytochemicals. The pharmaceutical and construction industries are both very interested in this plant since its metabolites have powerful bioactivities on humans.&nbsp;<em>Cannabinoids</em>&nbsp;are the most researched class of chemicals, primarily because of the vast range of pharmacological effects they have on humans, including psychoactive effe
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Sorrentino, Giuseppe. "Introduction to emerging industrial applications of cannabis (Cannabis sativa L.)." Rendiconti Lincei. Scienze Fisiche e Naturali 32, no. 2 (2021): 233–43. http://dx.doi.org/10.1007/s12210-021-00979-1.

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AbstractThe Italian Law of 22 November 2016 has legalized the cultivation of hemp, which drives the development of sustainable agriculture by generating new products with high added value in the new context of circular economy. Hemp cultivation is known for its low environmental impact, as hemp grows fast, suppresses weeds and does not need pesticides. It has no specialized parasites, favors pollination and improves the physical and chemical soil fertility. Recently, many countries have increased their interest in hemp (Cannabis Sativa L.), considering it as a climate-friendly crop that can mi
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Vetskov, Nikolay, Nikolay Kaloyanov, Ivaylo Hinkov, et al. "COMPARATIVE STUDY OF POLYPHENOLIC COMPOSITION AND REDUCING PROPERTIES OF EXTRACTS OF CANNABIS SATIVA L., CANNABIS INDICA AND CANNABIS HYBRID." Journal of Chemical Technology and Metallurgy 59, no. 2 (2024): 237–42. http://dx.doi.org/10.59957/jctm.v59.i2.2024.1.

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Cannabis Sativa L., Cannabis Indica and Cannabis Hybrid are widespread plant species that find legal use in many countries around the world. The first of them has found considerable application in medicine, cosmetics, building construction, textile and food industries. Cannabis Indica and Cannabis Hybrid are used as raw materials for the extraction of oils that are used as pain relievers as well as for recreation purposes. The aim of the present study is to compare the polyphenolic composition of extracts from the three types of plants, by the maceration method of dry green leaf mass consistin
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Capcanari, T. N., E. F. Covaliov, and C. Lu Negoița. "Hemp (<i>Cannabis sativa</i> L.) seeds nutritional aspects and food production perspectives: A review." Food systems 7, no. 1 (2024): 52–58. http://dx.doi.org/10.21323/2618-9771-2024-7-1-52-58.

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This review is devoted to an analysis of the hemp (Cannabis sativa L.) seeds’ nutritional aspects and food production perspectives, that can become a valuable source of multifunctional components for functional food production. Cannabis sativa L. is a multipurpose crop with lowenvironmental impact traditionally cultivated in Western cultures for fiber production. The propagation of synthetic fibers and the production of intoxicating drugs from certain narcotic strains resulted in the banning of its cultivation. Thus, culturing the varieties that are widely known as „industrial hemp“ has only b
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Špirović-Trifunović, Bojana, Dejan Nedeljković, Darko Stojićević, and Dragana Božić. "Fatty acids in wild hemp seeds (Cannabis sativa L. ssp. sativa var. spontanea Vavilov)." Acta herbologica 30, no. 1 (2021): 65–73. http://dx.doi.org/10.5937/actaherb2101065q.

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Wild hemp (Cannabis sativa L. ssp. sativa var. spontanea) is a special variety of industrial hemp (Cannabis sativa L. ssp. sativa), which is believed to have originated from the acclimatization of industrial hemp to the ruderal habitat conditions of Eastern Europe. In Serbia it is found along roads, on field edges, stubble fields, garbage dumps etc., but also as a weed in fields. Due to the great popularity of industrial hemp, which can be used for various purposes (as raw material in food and pharmaceutical industry, in the production of gluten-free flour, biodiesel, detergents, in folk medic
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Negoita, Catalina. "Critical analysis of hemp (Cannabis sativa L.) use: scientific, legislative and socio-economic aspects." Journal of Social Science 7, no. 1 (2024): 17–34. https://doi.org/10.52326/jss.utm.2024.7(1).02.

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Cannabis sativa L. culture has encountered various legislative challenges throughout history, and these have varied according to the social, political and economic context of each period. Historical stigma and prohibitions brought restrictions on cannabis, and anti-drug and prohibition policies adopted in the 20th century led to the prohibition of the cultivation of Cannabis sativa L. Its incorrect association with drugs of abuse and its classification as a narcotic substance complicated the legislation. Problems in differentiating between recreational and medical use have created confusion in
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badrana, Fadwa, Abdelrhani Mokhtari, Najete Safini, Abdelmajid Soulaymani, Elmostafa El fahime, and Hamid El Amri. "Systematic review and meta-analysis for the biotechnological production of THC in Morocco." E3S Web of Conferences 319 (2021): 02012. http://dx.doi.org/10.1051/e3sconf/202131902012.

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Cannabinoids have promising therapeutic potential. Δ9-tetrahydrocannabinol (THC), the most important psychotropic active ingredient of Cannabis Sativa L, has been the subject of several chemical, pharmacological and biosynthetic studies. In this context, a meta-analysis of biotechnological processes applied to the production of recombinant cannabinoid THC worldwide was carried out. The objective was to highlight the potential of these processes on the Moroccan variety of Cannabis Sativa. The PubMed, ScienceDirect and Web of Science search motors were used to search for original scientific work
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Pexová Kalinová, Jana, Naděžda VRCHOTOVÁ, Jan TŘÍSKA, and Šárka HELLEROVÁ. "Industrial hemp (Cannabis sativa L.) as a possible source of cannabidiol." Journal of Central European Agriculture 22, no. 1 (2021): 110–18. http://dx.doi.org/10.5513/jcea01/22.1.2860.

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Zagožen, Marjeta, Andreja Čerenak, and Samo Kreft. "Cannabigerol and cannabichromene in Cannabis sativa L." Acta Pharmaceutica 71, no. 3 (2020): 355–64. http://dx.doi.org/10.2478/acph-2021-0021.

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Abstract In addition to delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), other phytocannabinoids, such as cannabigerol (CBG) and cannabichromene (CBC), also have beneficial effects on human health. A high content of CBG is found in plants with the B0 genotype, whereas CBC is independent of the allelic chemotype locus B. In basic research models such as mice or rats, CBG has demonstrated anticancer properties, particularly against breast cancer. CBG has shown anti-inflammatory effects on murine colitis and on inflammatory bowel disease as well as stimulatory effects on the feeding beha
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Fernandes Ramos, Mariana, David Boston, Chad A. Kinney, João A. Coblinski, and Flávio A. de Oliveira Camargo. "Sourcing Cannabis sativa L. by thermogravimetric analysis." Science & Justice 61, no. 4 (2021): 401–9. http://dx.doi.org/10.1016/j.scijus.2021.03.002.

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Mnekin, Léonid, and Lionel Ripoll. "Topical Use of Cannabis sativa L. Biochemicals." Cosmetics 8, no. 3 (2021): 85. http://dx.doi.org/10.3390/cosmetics8030085.

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Cannabis sativa L. plant is currently attracting increasing interest in cosmetics and dermatology. In this review, the biologically active compounds of hemp are discussed. Particularly the complex interactions of cannabinoids with the endocannabinoid system of the skin to treat various conditions (such as acne, allergic contact dermatitis, melanoma, and psoriasis) with clinical data. Moreover, the properties of some cannabinoids make them candidates as cosmetic actives for certain skin types. Hemp seed oil and its minor bioactive compounds such as terpenes, flavonoids, carotenoids, and phytost
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Gottwald, Reinhold. "Entomologische Untersuchungen an Hanf (Cannabis sativa L.)." Gesunde Pflanzen 54, no. 5 (2002): 146–52. http://dx.doi.org/10.1046/j.1439-0345.2002.02002.x.

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Costa, Alana, Arquimedes Gasparotto, Cícero Pereira, Emerson Lourenço, Alana Garcia, and Helena Joaquim. "Genotoxicity study of Cannabis sativa L. extract." Toxicology Reports 14 (June 2025): 101864. https://doi.org/10.1016/j.toxrep.2024.101864.

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Nadig, Alexandra. "Cannabis sativa L. – eine Pflanze mit Doppelnutzen." Zeitschrift für Phytotherapie 30, no. 04 (2009): 200–206. http://dx.doi.org/10.1055/s-0029-1239339.

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Aiello, Gilda, Elisa Fasoli, Giovanna Boschin, et al. "Proteomic characterization of hempseed ( Cannabis sativa L.)." Journal of Proteomics 147 (September 2016): 187–96. http://dx.doi.org/10.1016/j.jprot.2016.05.033.

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Dinusheva, Slavica, and Aleksandra Pecova. "Antimicrobial properties of Cannabis Sativa L. plant." Macedonian Pharmaceutical Bulletin 68, no. 04 (2022): 129–30. http://dx.doi.org/10.33320/maced.pharm.bull.2022.68.04.058.

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Ashwani, Kumar, Husaini Zehra, Lehari Khyati, Yadav Ritika, and Tomar Supriya. "Qualitative Physiochemical and Phytochemical Analysis of Saintly Herb Indian Hemp (Cannabis sativa L.) with UV-VIS Spectrophotometer." Qualitative Physiochemical and Phytochemical Analysis of Saintly Herb Indian Hemp (Cannabis sativa L.) with UV-VIS Spectrophotometer 8, no. 12 (2024): 7. https://doi.org/10.5281/zenodo.10461455.

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The Cannabaceae family includes Cannabis sativa. Carl Linneus made the initial discovery of the species in 1753. Native to Eastern Asia, Cannabis sativa is an annual herbaceous flowering plant that is now widely cultivated and distributed throughout the world. Its phytochemical byproducts, hashish and marijuana, are the most produced and commonly used illegal drugs in Europe and India, where they are also deeply ingrained in Indian culture and religious customs. Although this plant is most well-known for its narcotic qualities, pre-clinical research on hemp derivatives &nbsp;revealed potential
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Watanakul, Phurin, Jessada Phattaralerphong, Kitsada Pitija, and Pattarawadee Sumthong Nakmee. "Terpenoid Profiling of Thai Strain Cannabis Leaves (Cannabis sativa L. subsp. sativa) by Headspace (HS) Couple with GC/MS." Journal of Pharmacy 4, no. 1 (2024): 3–11. https://doi.org/10.31436/jop.v4i1.225.

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Introduction: Cannabis terpenoids, especially volatile terpenes, were used for the classification of cannabis strains. The leaves of Cannabis sativa L. subsp. sativa Thai strain ‘Hang Krarok’ are used legally in traditional Thai medicines, cosmetics, and food ingredients in Thailand under the control of the tetrahydrocannabinol (if lower than 0.2% dry weight). One of the specific characteristics of this plant is the volatile oil which consists of mono-and the sesqui-terpenoids. Materials and methods: Fresh cannabis leaves were ground and 1 g samples were kept in gas chromatography/mass spectro
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Vetskov, N. B., I. S. Hinkov, K. V. Petkova- Parlapanska, E. D. Georgieva, G. D. Nikolova, and Y. D. Karamalakova. "The synergistic effect between Golden root and Cannabis Sativa L. Determination of the antioxidant activity of the extracts." Bulgarian Chemical Communications 56, no. D1 (2024): 19–25. http://dx.doi.org/10.34049/bcc.56.d.s2l6.

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The study aimed to compare the chemical composition and in vitro antioxidant activity of an extract obtained from Cannabis sativa L and golden root (Rhodiola rosea L), which are both used as natural anxiolytics. The phytochemical profile (HPLC - DAD analysis), total polyphenol content (TPC), and antioxidant capacity (AOC) of the combination of Rhodiola rosea extract and Cannabis sativa oil were investigated to study their effects. To determine the DPPH radicalscavenging activity, an electron paramagnetic radical spectrometer (EPR-X-band) was used as a promising technique. The results indicated
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Ćaćić, Marija, Aleksandra Perčin, Željka Zgorelec, and Ivica Kisić. "Evaluation of heavy metals accumulation potential of hemp (Cannabis sativa L.)." Journal of Central European Agriculture 20, no. 2 (2019): 700–711. http://dx.doi.org/10.5513/jcea01/20.2.2201.

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Metouekel, Amira, Fadwa Badrana, Rabie Kachkoul, et al. "Genetic Characterization and Chemical Identification of Moroccan Cannabis sativa (L.) Seeds: Extraction, and In Vitro and In Silico Biological Evaluation." Plants 13, no. 14 (2024): 1938. http://dx.doi.org/10.3390/plants13141938.

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This study investigated the molecular, phytochemical, and biological aspects of ten local Moroccan traditional landrace Cannabis seeds. Genetic polymorphisms were analyzed using DNA barcode determination, revealing two distinct molecular profiles: “Cannabis, species sativa, subspecies indica” and “Cannabis, species sativa, subspecies sativa”. Furthermore, a new sequence was identified by sequencing of the THCA synthase coding gene. Chemical profiling via HPLC-ESI-FULL-MS and GC-MS-MS of AMSD1 maceration extracts revealed 13 non-volatile chemicals, including 3 inactive cannabinoids and 3 polyph
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Rijavec, Tatjana, Svjetlana Janjić, and Darja Kocjan Ačko. "Revitalization of Industrial Hemp Cannabis sativa L. var. sativa in Slovenia: a Study of Green Hemp Fibres." TEKSTILEC 60, no. 1 (2017): 36–48. http://dx.doi.org/10.14502/tekstilec2017.60.36-48.

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Negoita, Catalina. "CRITICAL ANALYSIS OF HEMP (CANNABIS SATIVA L.) USE: SCIENTIFIC, LEGISLATIVE AND SOCIO-ECONOMIC ASPECTS." JOURNAL OF SOCIAL SCIENCES 7, no. 1 (2024): 17–34. http://dx.doi.org/10.52326/jss.utm.2024.7(1).02.

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Cannabis sativa L. culture has encountered various legislative challenges throughout history, and these have varied according to the social, political and economic context of each period. Historical stigma and prohibitions brought restrictions on cannabis, and anti-drug and prohibition policies adopted in the 20th century led to the prohibition of the cultivation of Cannabis sativa L. Its incorrect association with drugs of abuse and its classification as a narcotic substance complicated the legislation. Problems in differentiating between recreational and medical use have created confusion in
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Li, Jia, Guan Wang, Yu Qin, et al. "Neuroprotective constituents from the aerial parts of Cannabis sativa L. subsp. sativa." RSC Advances 10, no. 53 (2020): 32043–49. http://dx.doi.org/10.1039/d0ra04565a.

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5 new compounds including 3 new cannabinoids, cannabisativas A–C, 2 new phenolic acids, (7Z,9Z)-cannabiphenolic acid A and (8S,9Z)-cannabiphenolic acid B, together with 12 known compounds, were isolated from the aerial parts of Cannabis sativa L. subsp. sativa.
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Wizenberg, Sydney B., Jillian Muir-Guarnaccia, and Lesley G. Campbell. "Cosexuality Reduces Pollen Production and Fitness in Cannabis sativa L." Plants 12, no. 21 (2023): 3731. http://dx.doi.org/10.3390/plants12213731.

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Cannabis sativa L. is cultivated globally for its cannabinoid-dense inflorescences. Commercial preference for sinsemilla has led to the development of methods for producing feminized seeds through cross-pollination of cosexual (masculinized) female plants. Although the induction of cosexuality in Cannabis plants is common, to date, no work has empirically tested how masculinization of female Cannabis plants impacts male flowering, pollen production, pollen fitness, and related life-history trade-offs. Here, we cultivated a population of Cannabis plants (CFX-2) and explored how the route to cos
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Lowe, Henry, Blair Steele, Joseph Bryant, Ngeh Toyang, and Wilfred Ngwa. "Non-Cannabinoid Metabolites of Cannabis sativa L. with Therapeutic Potential." Plants 10, no. 2 (2021): 400. http://dx.doi.org/10.3390/plants10020400.

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The cannabis plant (Cannabis sativa L.) produces an estimated 545 chemical compounds of different biogenetic classes. In addition to economic value, many of these phytochemicals have medicinal and physiological activity. The plant is most popularly known for its two most-prominent and most-studied secondary metabolites—Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD). Both Δ9-THC and CBD have a wide therapeutic window across many ailments and form part of a class of secondary metabolites called cannabinoids—of which approximately over 104 exist. This review will focus on non-cannabinoid
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BILALIS, Dimitrios, Stella KARIDOGIANNI, Ioannis ROUSSIS, Varvara KOUNELI, Ioanna KAKABOUKI, and Antigolena FOLINA. "Cannabis sativa L.: A New Promising Crop for Medical and Industrial Use." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Horticulture 76, no. 2 (2019): 145. http://dx.doi.org/10.15835/buasvmcn-hort:2019.0020.

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The cannabis plant was discovered 10,000 years ago without its exact use being known in China and Central Asia. Equally highly interested in this plant are the pharmaceutical and construction sectors. The cultivation of Cannabis sativa L. varieties containing more than 0.2% tetrahydrocannabinol (THC) has been legalized by the law 4523/2018 in Greece for the sole purpose of producing end-products of medicinal cannabis. The use of medicinal cannabis is important for dealing with chronic diseases. As far as cannabis cultivated for industrial use is concerned, there is a significant increase in th
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Bernstein, Nirit, Jonathan Gorelick, and Sraya Koch. "Interplay between chemistry and morphology in medical cannabis (Cannabis sativa L.)." Industrial Crops and Products 129 (March 2019): 185–94. http://dx.doi.org/10.1016/j.indcrop.2018.11.039.

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48

Melzig, Matthias F. "Cannabis – was wirkt wie?" Zeitschrift für Phytotherapie 44, no. 01 (2023): 3–4. http://dx.doi.org/10.1055/a-1962-0761.

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Cannabis, genauer die oberirdischen Pflanzenteile, v. a. Triebspitzen und Blüten der weiblichen Pflanze von Cannabis sativa L., enthalten mehr als 500 Verbindungen, von denen mindestens 100 als Cannabinoide bzw. Phytocannabinoide bekannt sind. Weitere Sekundärstoffe sind Flavonoide und Terpene.
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Kubiliene, Asta, Karolina Mickute, Juste Baranauskaite, Mindaugas Marksa, Arunas Liekis, and Ilona Sadauskiene. "The Effects of Cannabis sativa L. Extract on Oxidative Stress Markers In Vivo." Life 11, no. 7 (2021): 647. http://dx.doi.org/10.3390/life11070647.

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In recent decades, a lot of attention has been paid to Cannabis sativa L. due to its useful applications, including in fibers, oil, food for humans and animals, and therapeutics. The present study aimed to determine antioxidant activity of cannabinoids in Cannabis sativa L. in vivo, evaluating the possible antioxidative effect of Cannabis sativa L. extract (CE) on malondialdehyde (MDA) and glutathione (GSH) concentrations as well as on catalase (CAT) activity in BALB/c mice. In total, 40 mice were divided into five equal groups: the aluminum group (7.5 mg AlCl3/kg/d (0.15 LD50), the saline gro
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Valizadehderakhshan, Mehrab, Abolghasem Shahbazi, Masoud Kazem-Rostami, Matthew Scott Todd, Arnab Bhowmik, and Lijun Wang. "Extraction of Cannabinoids from Cannabis sativa L. (Hemp)—Review." Agriculture 11, no. 5 (2021): 384. http://dx.doi.org/10.3390/agriculture11050384.

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Cannabis plant has long been execrated by law in different nations due to the psychoactive properties of only a few cannabinoids. Recent scientific advances coupled with growing public awareness of cannabinoids as a medical commodity drove legislation change and brought about a historic transition where the demand rose over ten-fold in less than five years. On the other hand, the technology required for cannabis processing and the extraction of the most valuable chemical compounds from the cannabis flower remains the bottleneck of processing technology. This paper sheds light on the downstream
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