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1

Kornerup, Tore. "CAPILLARY FRAGILITY AND DIABETIC RETINOPATHY." Acta Ophthalmologica 33, no. 5 (2009): 583–98. http://dx.doi.org/10.1111/j.1755-3768.1955.tb03332.x.

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2

Forster, PJG, and AD Wright. "Capillary Fragility at High Altitude." Clinical Science 75, s19 (1988): 14P. http://dx.doi.org/10.1042/cs075014pc.

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3

West, John B. "Fragility of pulmonary capillaries." Journal of Applied Physiology 115, no. 1 (2013): 1–15. http://dx.doi.org/10.1152/japplphysiol.00229.2013.

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Although the pulmonary capillaries were discovered in 1661, the ultrastructure of the wall was not elucidated until 60 years ago. Electron micrographs then showed that only 0.2 μm of tissue separated the capillary endothelium from the alveolar space over much of the area. In retrospect this vanishingly small protective layer should have alerted physiologists to the potential fragility of the capillaries, but this was not appreciated until almost 40 years later. This predicament is unique to pulmonary capillaries. No other capillaries in the body are shielded from the outside environment by suc
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Hunter, D. J., J. R. Smart, and L. Whitton. "Increased capillary fragility at high altitude." BMJ 292, no. 6513 (1986): 98. http://dx.doi.org/10.1136/bmj.292.6513.98.

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5

Kulkarni, Shradha A., Evan Strobelt, and Zaven Sargsyan. "Capillary Fragility in Zika Virus Infection." American Journal of Medicine 130, no. 2 (2017): e59. http://dx.doi.org/10.1016/j.amjmed.2016.10.008.

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6

Feinstein, A. R. "Tourniquet test for capillary fragility in diabetes." JAMA: The Journal of the American Medical Association 255, no. 3 (1986): 323b—323. http://dx.doi.org/10.1001/jama.255.3.323b.

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Feinstein, A. R. "Tourniquet Test for Capillary Fragility in Diabetes." JAMA: The Journal of the American Medical Association 255, no. 3 (1986): 323. http://dx.doi.org/10.1001/jama.1986.03370030041014.

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8

Wienert, Volker. "Efficacy of aescin on the capillary fragility in men." International Journal of Angiology 6, no. 02 (2011): 115–17. http://dx.doi.org/10.1007/bf01616680.

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9

Wiwanikit, Viroj. "Capillary Fragility, Zika Virus Infection, and Basic Screening Test." American Journal of Medicine 130, no. 6 (2017): e277. http://dx.doi.org/10.1016/j.amjmed.2017.01.047.

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10

de Godoy, Lívia Maria Pereira, Ana Carolina Pereira de Godoy, Henrique Jose Pereira de Godoy, and Jose Maria Pereira de Godoy. "Control of ochre dermatitis with aminaphtone in an adolescent." Our Dermatology Online 14, no. 3 (2023): 301–3. http://dx.doi.org/10.7241/ourd.20233.15.

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The aim of this manuscript is to report the case of a 22-year-old adolescent who presented with brownish patches on the skin of her lower legs persistent since the age of eleven years. She was treated by a dermatologist since the age of twelve years with a clinical diagnosis of ochre dermatitis confirmed by a biopsy. The patient was treated for two years without a success and was sent to a vascular surgeon at fourteen years of age. The diagnosis was confirmed, and the venous duplex scan discarded the possibility of a macrocirculation abnormality. The patient was treated with aminaphtone with t
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Kitchens, CS, and JF Pendergast. "Human thrombocytopenia is associated with structural abnormalities of the endothelium that are ameliorated by glucocorticosteroid administration." Blood 67, no. 1 (1986): 203–6. http://dx.doi.org/10.1182/blood.v67.1.203.203.

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Abstract Capillary fragility is characteristic of severe thrombocytopenia. This mechanical weakness may not be solely accounted for by decreased ability of platelets to repair endothelial breaks. Platelets may have a role in maintaining endothelial hemostasis. This laboratory has demonstrated thinning of capillary endothelium in experimental thrombocytopenia. We now report similar findings in human thrombocytopenia. Capillary endothelium supplying either skin or skeletal muscle was found to have a mean thickness only half that of normal as well as frequent very thinned areas, including some fe
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Kitchens, CS, and JF Pendergast. "Human thrombocytopenia is associated with structural abnormalities of the endothelium that are ameliorated by glucocorticosteroid administration." Blood 67, no. 1 (1986): 203–6. http://dx.doi.org/10.1182/blood.v67.1.203.bloodjournal671203.

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Capillary fragility is characteristic of severe thrombocytopenia. This mechanical weakness may not be solely accounted for by decreased ability of platelets to repair endothelial breaks. Platelets may have a role in maintaining endothelial hemostasis. This laboratory has demonstrated thinning of capillary endothelium in experimental thrombocytopenia. We now report similar findings in human thrombocytopenia. Capillary endothelium supplying either skin or skeletal muscle was found to have a mean thickness only half that of normal as well as frequent very thinned areas, including some fenestratio
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Cantero, A., and L. C. Simard. "A Study of the Tumor Necrotizing Effects with S. Marcenscens Polysaccharide in Mice Transplanted Sarcomas (S-37)." Revista Brasileira de Cancerologia 4, no. 7 (2023): 48–50. http://dx.doi.org/10.32635/2176-9745.rbc.1951v4n7.4247.

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Mice bearing sarcoma implants (S.37) obtained from the National Câncer Institute received sublethal dosage of Serrata Marcenscens polysaccharide (as obtained from Dr. Shear). The cytotoxic like action, characterized by hemorrhage and necrosis in the tumor mass has been investigated, as to its relationship to an anaphylactic action, or as due to an increased capillary fragility. Results are herewith reported.
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West, John B. "Role of the fragility of the pulmonary blood-gas barrier in the evolution of the pulmonary circulation." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 304, no. 3 (2013): R171—R176. http://dx.doi.org/10.1152/ajpregu.00444.2012.

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In 1953 Frank Low published the first high-resolution electron micrographs of the human pulmonary blood-gas barrier. These showed that a structure only 0.3-μm thick separated the capillary blood from the alveolar gas, immediately suggesting that the barrier might be vulnerable to mechanical failure if the capillary pressure increased. However, it was 38 years before stress failure was recognized. Initially it was implicated in the pathogenesis of High Altitude Pulmonary Edema, but it was soon clear that stress failure of pulmonary capillaries is common. The vulnerability of the blood-gas barri
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Cesarone, M. R., A. Ricci, A. Di Renzo, G. Belcaro, and M. Dugall. "Efficacy of Topical Treatment with Aescin + Essential Phospholipids Gel on Capillary Fragility." Angiology 55, no. 6_suppl (2004): S23—S25. http://dx.doi.org/10.1177/000331970405500606.

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Iriti, Marcello, Elena Maria Varoni, and Sara Vitalini. "Bioactive Compounds in Health and Disease – Focus on Rutin." Bioactive Compounds in Health and Disease 6, no. 10 (2023): 235. http://dx.doi.org/10.31989/bchd.v6i10.1145.

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The flavonoid rutin was first isolated from rue (Ruta graveolens L.) and is used therapeutically as a capillary stabilizing and vasoprotective agent to reduce capillary fragility, although no health claims have been approved in the EU. This article briefly focuses on physicochemical properties, occurrence in foods and oral bioavailability of rutin, with emphasis on human studies. According to the available information, rutin can be considered a promising bioactive compound, despite the paucity of clinical trials. In addition to its therapeutic relevance in pathological and pathophysiological c
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Fu, Zhenxing, Gregory P. Heldt, and John B. West. "Increased fragility of pulmonary capillaries in newborn rabbit." American Journal of Physiology-Lung Cellular and Molecular Physiology 284, no. 5 (2003): L703—L709. http://dx.doi.org/10.1152/ajplung.00276.2002.

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The pulmonary capillaries of neonatal lungs are potentially vulnerable to stress failure because of the complex changes in the pulmonary circulation that occur at birth. We perfusion fixed the lungs from nine anesthetized newborn rabbits at capillary transmural pressures (Ptm) of 5 ± 5, 10 ± 5, and 15 ± 5 cmH2O. Normal microscopic appearances were seen at Ptm values of 5 ± 5 and 10 ± 5 cmH2O, but massive airway edema was observed in lungs perfused at a Ptm of 15 ± 5 cmH2O. Consistent with this, no disruptions of the alveolar epithelium were observed at Ptm values of 5 ± 5 cmH2O, but mean value
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Tarnev, Tsvetan, Cychy Cychy, Corina Andronescu, Martin Muhler, Wolfgang Schuhmann, and Yen-Ting Chen. "A Universal Nano-capillary Based Method of Catalyst Immobilization for Liquid-Cell Transmission Electron Microscopy." Angew. Chem. Int. Ed. 59 (March 2, 2020): 5586–90. https://doi.org/10.1002/anie.201916419.

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A universal nano-capillary based method for sample deposition on the silicon nitride membrane of liquid-cell transmission electron microscopy (LCTEM) chips is demonstrated. It is applicable to all substances which can be dispersed in a solvent and are suitable for drop casting, including catalysts, biological samples, and polymers. Most importantly, this method overcomes limitations concerning sample immobilization due to the fragility of the ultra-thin silicon nitride membrane required for electron transmission. Thus, a straightforward way is presented to widen the research area of deposited
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19

Doughty, H. A., and C. Beardmore. "Bleeding Time at Altitude." Journal of the Royal Society of Medicine 87, no. 6 (1994): 317–19. http://dx.doi.org/10.1177/014107689408700605.

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Disorders of coagulation during ascent to high altitude in the unacclimatized are well recognized. In order to document the sequence of haematological changes, the bleeding time was estimated weekly in six climbers during a six week climb. The median bleeding time was shown to increase by 50% between the first and fourth week, it then plateaued during continued ascent to 5700 m. During the sixth week the bleeding time rapidly reverted to baseline levels whilst still at altitude. The observations might be explained by the compensatory changes in coagulation factors following the initial prothro
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Fu, Jack B., and Shinichiro Morishita. "Inpatient Rehabilitation of Hematopoietic Stem Cell Transplant Patients." American Journal of Physical Medicine & Rehabilitation 103, no. 3S (2024): S46—S51. http://dx.doi.org/10.1097/phm.0000000000002408.

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Abstract Hematopoietic stem cell transplants play an important role in the treatment of cancer, particularly hematologic malignancies. These patients can encounter functional impairments unique to hematopoietic stem cell transplant, including deconditioning, cancer-related fatigue, steroid myopathy, graft versus host disease, and capillary leak syndrome. Medical fragility and increased risk of infection may make rehabilitation challenging on the acute care and postacute care settings. Patients admitted to acute inpatient rehabilitation experience a high rate of transfer to the primary acute se
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Guolo, E., P. Romagnoni, and F. Peron. "Capillary rising damp in Venetian context: state of the art and numerical simulation." Journal of Physics: Conference Series 2069, no. 1 (2021): 012046. http://dx.doi.org/10.1088/1742-6596/2069/1/012046.

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Abstract The fragility of Venice and its buildings are linked to the floods, observed since ancient times and emphasized in recent years: the periodic sea level rise, accompanied by rising damp, are the main causes of the alteration. In particular, the rising damp causes a series of complex diseases in the historic buildings, such as physical decay, chemical or biological, with loss of aesthetic and economic value. In addition, greater heat dispersion and reduced thermal comfort can also occur in interior spaces, with consequent risks for human health. This is a sign of “Sick Building Syndrome
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Tomson, C. R. V., S. M. Channon, I. S. Parkinson, et al. "Correction of subclinical ascorbate deficiency in patients receiving dialysis: Effects on plasma oxalate, serum cholesterol, and capillary fragility." Clinica Chimica Acta 180, no. 3 (1989): 255–64. http://dx.doi.org/10.1016/0009-8981(89)90007-7.

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Pinto, Thiago Maurício de Souza, Fabrini Luiz Alves Almeida, Julianna Oliveira de Lucas Xavier, et al. "Biopharmacotechnical and physical properties of solid pharmaceutical forms containing rutin commercially acquired in Juiz de Fora city, Brazil." Acta Scientiarum. Health Sciences 42 (July 9, 2020): e52212. http://dx.doi.org/10.4025/actascihealthsci.v42i1.52212.

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Rutin is a flavonoid used in clinical practice to treat capillary fragility and prevent bleeding due to its wide variety of pharmacological actions, including antioxidant, anti-inflammatory, anti-allergic, antiproliferative, and anticarcinogenic activities. In this study, the biopharmacotechnical and physical properties of film-coated tablets containing rutin marketed in drugstores were evaluated. Using samples from three batches called A, B and C, we determined the average weight, disintegration time, hardness, content and dissolution profile, and kinetics of the tablets. The samples demonstr
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Mitra, Zarea Nemati. "Investigating marketing of children's food stuff and methods of advertising in Iran." International Journal of Trend in Scientific Research and Development 1, no. 4 (2017): 1–11. https://doi.org/10.31142/ijtsrd78.

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Marketing of food stuff to increase sale is possible with different methods. Capillary marketing is one of the most influential techniques in the issue of more sales in organizations especially in terms of selling food stuff. Food stuff should be sold in a short time due to the short durability. People who make better use of capillary marketing to supply their products and services can sell better and faster. Dependency of Iran's economy on oil incomes and affectability of such incomes from political, economic and international issues cause vulnerability and fragility of the economy. One o
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Torrente, Y., M. Belicchi, C. Marchesi, et al. "Autologous Transplantation of Muscle-Derived CD133+ Stem Cells in Duchenne Muscle Patients." Cell Transplantation 16, no. 6 (2007): 563–77. http://dx.doi.org/10.3727/000000007783465064.

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Duchenne muscular dystrophy (DMD) is a lethal X-linked recessive muscle disease due to defect on the gene encoding dystrophin. The lack of a functional dystrophin in muscles results in the fragility of the muscle fiber membrane with progressive muscle weakness and premature death. There is no cure for DMD and current treatment options focus primarily on respiratory assistance, comfort care, and delaying the loss of ambulation. Recent works support the idea that stem cells can contribute to muscle repair as well as to replenishment of the satellite cell pool. Here we tested the safety of autolo
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Mansur, Fadlul Azim Fauzi, and Nurul Azmawati Mohamed. "Islands of White in a Sea of Red: A Cutaneous Manifestation of Dengue Fever in a Pregnant Woman." Malaysian Journal of Science Health & Technology 7, no. 3 (2021): 64–66. http://dx.doi.org/10.33102/mjosht.v7i3.203.

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Dengue fever is a significant public health problem in Asia, resulting in serious morbidity and even mortality. It is mainly known for causing severe constitutional symptoms and bleeding, often resulting in haemorrhagic shock. Dengue fever may manifest cutaneously in several forms. These include petechial rash, maculopapular rash and what has been termed as islands of white in a sea of red. Most can be attributed to capillary fragility, which led to tests such as the tourniquet test. This case highlights the dengue fever cutaneous presentation of islands of white in a sea of red in a multigrav
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Kimak, Agnieszka, and Agnieszka Żebrowska. "Therapeutic Approach in Pigmented Purpuric Dermatoses—A Scoping Review." International Journal of Molecular Sciences 25, no. 5 (2024): 2644. http://dx.doi.org/10.3390/ijms25052644.

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Pigmented purpuric dermatoses (PPD) encompass a group of chronic skin conditions characterized by the presence of petechiae, purpura, and pigmentation changes. While generally benign, these dermatoses can be persistent and aesthetically bothersome. Key clinical features include red to brownish patches with a distinctive “cayenne pepper” appearance, predominantly localized on the lower extremities, particularly the shins. Subtypes include Schamberg disease, Majocchi’s disease, Gougerot–Blum disease, Ducas and Kapetanakis pigmented purpura, and lichen aureus. Diagnosis relies primarily on clinic
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Napolitano, Angela, Laura De Michieli, Giulio Sinigiani, Tamara Berno, Alberto Cipriani, and Luca Spiezia. "Thromboembolic and Bleeding Events in Transthyretin Amyloidosis and Coagulation System Abnormalities: A Review." Journal of Clinical Medicine 12, no. 20 (2023): 6640. http://dx.doi.org/10.3390/jcm12206640.

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Transthyretin amyloidosis (ATTR) is a group of diseases caused by the deposition of insoluble fibrils derived from misfolded transthyretin, which compromises the structure and function of various organs, including the heart. Thromboembolic events and increased bleeding risk are among the most important complications of ATTR, though the underlying mechanisms are not yet fully understood. Transthyretin plays a complex role in the coagulation cascade, contributing to the activation and regulation of the coagulation and fibrinolytic systems. The prevalence of atrial fibrillation, cardiac mechanica
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Shekhar, Neema, Ranjan Eeshaan, Durga Madhab Tripathy, Mani Siddharth, and Oberoi Bhavni. "Pigmented purpuric dermatoses: A review." Pigment International 11, no. 1 (2024): 1–11. http://dx.doi.org/10.4103/pigmentinternational.pigmentinternational_53_23.

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Pigmented purpuric dermatosis (PPD) comprises a group of skin conditions characterized by flat, nonpalpable petechiae and purpura as a result of capillaritis. Although the precise cause of PPD is as yet unknown, increased vascular permeability and capillary fragility are key factors in its pathophysiology. PPD has diverse clinical presentations, but the histopathology of all these variants essentially remains the same. The initial purpuric lesions develop a golden-brown hue owing to hemosiderin absorption and eventually progress to chronic pigmentary changes. These lesions, which often affect
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Arafa Musa, Ehab M. Mostafa, Mohammad M. Al-Sanea, Shaimaa R. Ahmed, Gomaa Mostafa-Hedeab, and Mohamed A. Abdelgawad. "Insights Studies for Certain Natural FDA Approved Polyphenolics and Repurposing for COVID-19." International Journal of Research in Pharmaceutical Sciences 11, SPL1 (2020): 1390–95. http://dx.doi.org/10.26452/ijrps.v11ispl1.3667.

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Natural polyphenolic drugs were approved for treatment of various diseases. Diosmin, rutin, quercetin, aesculin, genistein, hesperidin and silybin are known for their safety and have been applied for several human disorders including cancer, cardiovascular disorders, atherosclerosis, oxidative stress, capillary fragility, liver and pancreatic disorders and others. As the structures of the selected polyphenolic compounds possess variable chemical moieties with diverse chemical and electronic characters, these properties have been employed for further insights studies to predict new applications
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Troуan, Vyacheslav, and Bogdan Kindras. "Increasing the crack resistance of high-strength self-compacting concrete." Technology audit and production reserves 1, no. 1(57) (2021): 17–24. http://dx.doi.org/10.15587/2706-5448.2021.225500.

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The object of research is high-strength self-compacting concrete, which does not require additional vibration during laying. One of the most problematic issues of high-strength self-compacting concretes is increased cracking, associated with large shrinkage deformations of such concretes and their fragile destruction.
 A decrease in shrinkage deformations of concrete was established when part of the cement was replaced to mineral additives. This effect is explained by a decrease of the cement content and, accordingly, a decrease of the chemical component of the autogenous shrinkage of con
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Ebrahim, Hanan S., Nourhan M. Deyab, Basamat S. Shaheen, Ahmed M. M. Gabr, and Nageh K. Allam. "In Vitro: The Extraordinary Enhancement in Rutin Accumulation and Antioxidant Activity in Philodendron “Imperial Red” Plantlets Using Ti-Mo-Ni-O Nanotubes as a Novel Elicitor." BioTech 13, no. 3 (2024): 24. http://dx.doi.org/10.3390/biotech13030024.

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Rutin, a flavonoid phytochemical compound, plays a vital role in human health. It is used in treating capillary fragility and has anti-Alzheimer, anti-inflammatory, and antioxidant effects. In this study, Ti-Mo-Ni-O nanotubes (NTs) were used, for the first time, in an unprecedented plant biotechnology application, wherein in vitro Philodendron shoots (Philodendron erubescens) known as “Imperial Red” were targeted for rutin accumulation. The antioxidant responses and the accumulation of rutin were evaluated in treated Philodendron erubescens (P. erubescens) shoots using 5.0 mg/L of Ti-Mo-Ni-O N
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Rezazadeh, Arash, Sandra C. Hollensead, Damian A. Laber, and Goetz H. Kloecker. "Intracranial Hemorrhage in a Patient with Osteogenesis Imperfecta Due to Inherited and Acquired Platelet Dysfunction." Blood 108, no. 11 (2006): 3960. http://dx.doi.org/10.1182/blood.v108.11.3960.3960.

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Abstract A 42 year-old man with Osteogenesis Imperfecta (OI) had three episodes of spontaneous Subdural Hematoma (SH) after binge drinking. There is no remote history of abnormal bleeding or easy bruising despite multiple fractures. Medications included Aspirin (ASA). The first and second SH occurred within the preceding year and were treated conservatively. The third SH occurred while on ASA and drinking more than 500cc liquor/day. The Platelet Function Assay (PFA-100) was significantly abnormal (see table). After platelet transfusions the SH was surgically evacuated without complications. An
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Jørgensen, J. O. L., S. A. Pedersen, J. Ingerslev, F. J. Møller, and J. S. Christiansen. "Growth hormone (GH) therapy in GH-deficient patients, the plasma Factor VIII-von Willebrand factor complex, and capillary fragility. A double-blind, placebo-controlled crossover study." Scandinavian Journal of Clinical and Laboratory Investigation 50, no. 4 (1990): 417–20. http://dx.doi.org/10.3109/00365519009091600.

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Espinoza, Betty Manrique, Ana Rivera Almaraz, and Aaron Salinas Rodriguez. "HYPERGLYCEMIA AND INCIDENCE OF FRAILTY IN OLDER MEXICAN ADULTS LIVING IN RURAL AREAS." Innovation in Aging 3, Supplement_1 (2019): S680. http://dx.doi.org/10.1093/geroni/igz038.2511.

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Abstract Hyperglycemia is the main characteristic of diabetes and is the result of an absolute or partial deficit in the production or action of insulin. Recent evidence suggests that hyperglycemia increases the risk of frailty. This issue is of great importance for the Mexican population given the high prevalence of diabetes, particularly in older adults. Our objective was to analyze the association between hyperglycemia and the incidence of frailty in a cohort of rural older adults in Mexico. Prospective cohort study with 600 rural older adults, with measurements made in 2009, 2013 and 2018.
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Vyacheslav, Troуan, and Kindras Bogdan. "Increasing the crack resistance of high-strength self-compacting concrete." Technology audit and production reserves 1, no. 1(57) (2021): 17–24. https://doi.org/10.15587/2706-5448.2021.225500.

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<em>The object of research is high-strength self-compacting concrete, which does not require additional vibration during laying. One of the most problematic issues of high-strength self-compacting concretes is increased cracking, associated with large shrinkage deformations of such concretes and their fragile destruction.</em> <em>A decrease in shrinkage deformations of concrete was established when part of the cement was replaced to mineral additives. This effect is explained by a decrease of the cement content and, accordingly, a decrease of the chemical component of the autogenous shrinkage
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Anand, Siddharth, Pratibha Pawal-Aute, Shashikant Gunale, and Meenal Agarwal. "A Rare Pathogenic Variant in the SERPINF1 Gene in Association with Early-Onset Severe Presentation of Autosomal Recessive Type of Osteogenesis Imperfecta VI: A Case Report." Case Reports in Orthopedic Research 5, no. 3 (2023): 108–14. http://dx.doi.org/10.1159/000527988.

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Osteogenesis imperfecta (OI) refers to a group of genetic disorders with the typical clinical presentation of increased bone fragility. More than 90% of OI cases have an underlying genetic mutation in the collagen genes COL1A1 or COL1A2. However, there are now 22 different recognized OI subtypes based on the underlying gene implicated. OI type VI is caused by pathogenic variants in the serine proteinase inhibitor clade F (SERPINF1) gene. In this case study, the patient was a 4-year-old female, born in a consanguineous family, with a history of delayed gross motor milestones and recurrent fract
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Nizamov, F. Kh. "Chronic venous insufficiency after COVID-19: management of edema and pain syndromes." Ambulatornaya khirurgiya = Ambulatory Surgery (Russia) 18, no. 2 (2021): 151–53. http://dx.doi.org/10.21518/1995-1477-2021-18-2-151-153.

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Introduction. COVID-19 infection raises many questions regarding the health condition of patients after they have had COVID-19. The aim of this study is to examine the characteristic symptoms of chronic venous insufficiency in the postcovid period.Materials and methods. The materials that were used for work included the results of studying the medical aid appealability, characteristic symptoms, diagnosis and treatment of symptoms of chronic venous insufficiency in persons who have had the coronavirus infection. 47 patients presented with complaints about deterioration of their condition after
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Alkindi, Nour, Abdurahman Andijani, Samara Zavalkoff, and Karl Muchantef. "C4 (Clinical Case) Vascular Ehlers-Danlos Syndrome in the Paediatric Population: A Case Report of an Internal Bleed Caused by Ruptured Pseudoaneurysm." Paediatrics & Child Health 28, Supplement_1 (2023): e50-e51. http://dx.doi.org/10.1093/pch/pxad055.105.

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Abstract Introduction/Background Ehlers-Danols syndrome (EDS) is a connective tissue disease characterized by joint hypermobility, skin hyperextensibility and tissue fragility. EDS has six types. Type IV EDS: vascular EDS (vEDS), is rare but also the most malignant. Case Description We report a 15-year-old boy with a previous history of spontaneous colon perforation and two left shoulder dislocations. He presented with sudden onset abdominal pain, vomiting, dizziness, and lethargy with a Glasgow coma scale of 13. His abdomen was soft but mildly tender. He had a capillary refill of 3 seconds wi
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Gutiérrez, Lorena Suárez. "Iatrogenic Cushing Syndrome and Secondary Adrenal Insufficiency Due to an Interaction Between Fluticasone and Ritonavir." Journal of the Endocrine Society 5, Supplement_1 (2021): A136. http://dx.doi.org/10.1210/jendso/bvab048.274.

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Abstract Introduction: The interaction between corticosteroids and protease inhibitors (PIs) is a clearly described drug interaction. Several case series have been described.-Fluticasone is the one with the greatest potential risk of producing iatrogenic adrenal insufficiency given its pharmacokinetic characteristics. Clinical Case: 44-year-old woman diagnosed with HIV (human immunodeficiency virus) category B3 diagnosed in 1989; multiple antiretroviral treatments. Severe lipodystrophy Also HCV genotype IA. Bronchial asthma since 2000. A treatment with fluticasone 1 inh / 24h, salbutamol on de
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Fridriksdottir, Halla, Andreas Ørslev Rasmussen, Jens Lykkesfeldt, Maria Rossing, and Eva Birgitte Leinoe. "Reduced Vitamin C Levels in Patients with Bleeding of Unknown Cause and Generalized Joint Hypermobility." Blood 142, Supplement 1 (2023): 25. http://dx.doi.org/10.1182/blood-2023-173361.

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Introduction Vitamin C is essential for the synthesis of collagen. Ehler-Danlos syndrome (EDS) is a group of collagen disorders associated with generalized joint hypermobility (HM), bleeding and bruising. The genetic cause of the HM EDS subtype (hEDS) is unknown. Referral to haematology clinics may result in the diagnosis: bleeding of unknown cause (BUC), where no specific haemostatic treatment is available. However, it is a clinical experience, published in many textbooks, that bleeding, and bruising associated with EDS improve by oral intake of vitamin C. No previous studies examined vitamin
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Chami, Ariana de Sousa, Ellen Marcia Peres, Helena Ferraz Gomes, Dayana Carvalho Leite, Bruna Maiara Ferreira Barreto Pires, and Ariane da Silva Pires. "Cateteres venosos utilizados em adolescentes hospitalizados: estudo descritivo." Revista Recien - Revista Científica de Enfermagem 12, no. 38 (2022): 60–67. http://dx.doi.org/10.24276/rrecien2022.12.38.60-67.

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Avaliar os tipos de cateteres venosos utilizados por adolescentes hospitalizados. Estudo descritivo, documental, quantitativo, desenvolvido numa enfermaria de saúde do adolescente. A amostra constituiu-se de 30 prontuários de adolescentes submetidos à cateterização venosa. Os dados foram analisados através de estatística descritiva simples. Dos 85 dispositivos inseridos 78,8% (n=67) foram cateteres intravenosos periféricos e 9,4% (n=8) cateter central de inserção periférica. Quanto ao tempo da terapêutica 85,9% (n=73) destinaram-se àquelas com tempo &lt; que 21 dias. Em relação à farmacologia
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Franco, Katty Manrique, and Helard Manrique. "ODP521 THYROID HORMONE RESISTANCE SYNDROME." Journal of the Endocrine Society 6, Supplement_1 (2022): A783—A784. http://dx.doi.org/10.1210/jendso/bvac150.1620.

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Abstract Introduction The Thyroid hormone resistance syndrome is characterized by decreased tissue sensitivity to thyroid hormones. The incidence is about 1/50,000. We present two clinical cases of this disease. Clinical case 1A 59-year-old woman was evaluated for presenting palpitations for more than one year during exercise and rest. Also, she noticed heat even in the winter. Headache, hair loss, dry skin, capillary fragility were other complaints. She denies trembling in the hands, diarrhea and subcutaneous edemas. Cardiologist didn't find any cardiac alterations. Holter showed sinus tachyc
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Mazzolini, Anna, Valeria Fedeli, and Grazia Concilio. "Fragilit&agrave; urbane, mobilit&agrave; e politiche di contrasto al Covid in Africa." TERRITORIO, no. 97 (February 2022): 61–66. http://dx.doi.org/10.3280/tr2021-097-supplementooa12928.

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Alcuni contesti urbani necessitano di una mobilit&amp;agrave; permanente e flessibile di beni e persone come condizione per la vita collettiva e il sostentamento di base. Per questi contesti la pandemia ha concretizzato sfide che non possono essere analizzate con paradigmi cognitivi di origine americo-euro-centrica.Per la citt&amp;agrave; di Maputo, l'articolo riflette sulle fragilit&amp;agrave; urbane dell'Africa subsahariana, analizzando le misure di prevenzione della pandemia in relazione alla mobilit&amp;agrave; come fattore di co-produzione della citt&amp;agrave;. In tal senso si ridefini
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Valentina KIEFFER. "Aspect clinique et traitement des troubles trophiques d’origine veineuse avec peau intacte." Les pathologies vasculaires (anciennement ANGEIOLOGIE) 71, no. 02 (2019): 5. http://dx.doi.org/10.54695/mva.71.02.2182.

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Les maladies veineuses aiguës et chroniques font partiedes manifestations cliniques les plus répandues dans lapopulation, elles sont souvent mésestimées voir négligéeset seules les complications, fréquentes, invalidantes attirentl’attention.Les troubles trophiques sont un motif fréquent de consultation. Elles touchent près d’un individu sur deux.Dans cet ouvrage, nous allons traiter, les troubles trophiques d’origine veineuse sans lésion ouverte de la peau,caractéristiques des stades C1EAP à C5EAP de la maladieveineuse.Nous parlerons des télangiectasies qui correspondent àdes dilations intrad
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Malko, N. V., and Yu L. Bandrivskyi. "ASSESSING THE EFFECTIVENESS OF INTEGRATED TREATMENT IN ADOLESCENTS WITH CHRONIC CATARRHAL GINGIVITIS LIVING IN ENVIRONMENTALLY COMPROMISED AREAS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 24, no. 4 (2024): 168–72. https://doi.org/10.31718/2077-1096.24.4.168.

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The challenging ecological situation in Western Ukraine, coupled with natural geochemical factors such as deficiencies in fluorine and iodine, contributes to the deterioration of children's somatic and dental health. This underscores the urgent need to develop comprehensive treatment and preventive strategies to mitigate pathological processes in periodontal tissues and enhance treatment outcomes. Purpose: The study aimed to evaluate the effectiveness of treating chronic catarrhal gingivitis in children residing in environmentally polluted areas with iodine and fluorine deficiencies (the citie
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Doll, R. "Die Pflanzengesellschaften der Stehenden Gewässer im Norden der DDR Teil I. Die Gesellschaften des offenen Wassers (Characeen‐Gesellschaften)." Feddes Repertorium 100, no. 5-6 (1989): 281–324. http://dx.doi.org/10.1002/j.1522-239x.1989.tb00188.x.

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ZusammenfassungIn dieser Arbeit werden die Characeen‐Gesellschaften des nördlichen Teils der Deutschen Demokratischen Republik erfaßt und diskutiert.Es wurden die folgenden Gesellschaften unterschieden: Nitelletum flexilis Corill, 57, Nitelletum opacac Corill. 57, Nitelletum mucronatae Doll. ass. nov., Nitello‐Vaucherietum dichotomae (Pass. 04) Krausch 64, Charetum asperae Corill. 57, Charetum contrariae Corill. 57, Charetum ‘macrotelis’. Schmidt 81, Charetum delicatulae Doll ass. nov., Charetum intermediae A. Melzkr 77, Charetum tomentosac (Sauer 37) Corill. 57, Charetum polyacanthae Dambska
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Marassiro, Mateus João, Marcelo Leles Romarco de Oliveira, and Sergio Feliciano Come. "Three Decades of Agricultural Extension in Mozambique: Between Advances and Setbacks." Journal of Agricultural Studies 8, no. 2 (2020): 418. http://dx.doi.org/10.5296/jas.v8i2.16647.

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This article aims to analyze the intervention in the area of public agrarian extension in Mozambique, taking into consideration the trajectory of this policy in this country. The methodology used is the literature review and consultation of documents that guide the agrarian extension in the country. Documentary analysis of plans and programs that address the theme was performed, as well as the consultation of articles available on Google scholar published between 2000 and 2019, which brought discussions about agrarian extension. The results suggest that the intervention of extension technician
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Ostapets, M. O., I. I. Shevtsov, L. V. Karabut та M. E. Bereznyakova. "The effect of dry extract of Geranium Palustre herb on coagulation system = Вплив сухого екстракту трави герані болотної на систему зсідання крові". Journal of Education, Health and Sport 5, № 8 (2015): 119–25. https://doi.org/10.5281/zenodo.27484.

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<strong>Ostapets M</strong><strong>. </strong><strong>O</strong><strong>., </strong><strong>Shevtsov I</strong><strong>. </strong><strong>I</strong><strong>., </strong><strong>Karabut L</strong><strong>. </strong><strong>V</strong><strong>., </strong><strong>Bereznyakova</strong> <strong>M</strong><strong>. </strong><strong>E</strong><strong>.</strong> <strong>The</strong> <strong>effect</strong> <strong>of</strong> <strong>dry</strong> <strong>extract</strong> <strong>of</strong> <strong><em>Geranium</em></strong> <strong><em>Palustre</em></strong> <strong>herb</strong> <strong>on</strong> <s
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Núñez, Paula Gabriela, and Ana Inés Barelli. "Marcas urbanas y sentidos sociales en disputa. San Carlos de Bariloche, Argentina, 1966-1983." HiSTOReLo. Revista de Historia Regional y Local 5, no. 10 (2013): 164–96. http://dx.doi.org/10.15446/historelo.v5n10.38530.

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San Carlos de Bariloche es la principal localidad turística de la Patagonia argentina. Representa, por su dimensión, a la ciudad más poblada de la provincia de Río Negro y es la tercera en tamaño en la Patagonia. Su crecimiento demográfico ha estado nutrido por diferentes migraciones nacionales y extranjeras. De estas últimas las principales provienen de países latinoamericanos. El artículo apunta a indagar en la desvalorización de su migración más importante, la chilena, durante la segunda mitad del siglo XX. Esta exclusión se fortaleció entre 1966 y 1983, por las iniciativas estatales que ex
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