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1

Bonk, Robert J., Lori N. Simons, Timothy M. Scepansky, Nancy B. Blank, and Elisa B. Berman. "A Multidisciplinary Assessment of Chesteropoly as an Academic-Service Experience." Journal of Experiential Education 32, no. 2 (2009): 155–77. http://dx.doi.org/10.1177/105382590903200205.

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Because service-learning challenges participants to widen perspectives on social issues, we designed and assessed a multi-semester, multidisciplinary project with both academic and service objectives. In this project, undergraduate students developed a script and video centered on a board game designed to educate high-school students about their community, Chester, Pennsylvania. The script and video featured undergraduate students playing Chesteropoly, with deeded properties reflecting Chester's current community agencies, as well as business, educational, entertainment, and government groups
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Bentz, Bradford G., David E. Granstrom, and Shelby Stamper. "Seroprevalence of antibodies to Sarcocystis neurona in horses residing in a county of southeastern Pennsylvania." Journal of the American Veterinary Medical Association 210, no. 4 (1997): 517–18. http://dx.doi.org/10.2460/javma.1997.210.04.517.

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Objective To determine seroprevalence of Sarcocystis neurona-specific antibodies in a population of horses residing in Chester County, Pa. Design Prevalence survey. Sample Population 117 serum samples from selected members of a population of 580 Thoroughbred horses. Procedure Serum was analyzed for antibodies to Sarcocystic neurona, using a western blot. Information regarding age, sex, and housing of horse was obtained by questionnaire. Data were analyzed, using multivariable logistic regression. Results Seroprevalence was 45.3% (95% CI, 36.3 to 54.3%). A relationship was not found between ser
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Ozkaya, Sait I. "Using Probabilistic Decision Trees to Detect Fracture Corridors From Dynamic Data in Mature Oil Fields." SPE Reservoir Evaluation & Engineering 11, no. 06 (2008): 1061–70. http://dx.doi.org/10.2118/105015-pa.

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Summary This paper describes the procedure of building a probabilistic decision tree on the basis of the integration of data from multiple sources, conditional probabilities, and the application to map fracture corridors (FCs) in a mature oil field with abundant production data. A fracture corridor is a tabular, subvertical, fault-related fracture swarm that intersects the entire reservoir and extends laterally for several tens or hundreds of meters. Direct indicators of fracture corridors, such as image logs, flow profiles, well tests, and seismic fault maps, are sometimes insufficient to map
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Paul, Pijush K., Mark D. Zoback, and Peter H. Hennings. "Fluid Flow in a Fractured Reservoir Using a Geomechanically Constrained Fault-Zone-Damage Model for Reservoir Simulation." SPE Reservoir Evaluation & Engineering 12, no. 04 (2009): 562–75. http://dx.doi.org/10.2118/110542-pa.

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Summary Secondary fractures and faults associated with reservoir-scale faults affect both permeability and permeability anisotropy and hence play an important role in controlling the production behavior of a faulted reservoir. It is well known from geologic studies that there is a concentration of secondary fractures and faults in damage zones adjacent to large faults. Because there are usually inadequate data to fully incorporate damage-zone fractures and faults into reservoir-simulation models, this study uses the principles of dynamic rupture propagation from earthquake seismology to predic
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Marais, Richard M., Joanna Grabarek, Myria Ioannou, et al. "Abstract 1735: The discovery of PKMYT1 inhibitors to exploit synthetic lethality caused by replication stress." Cancer Research 85, no. 8_Supplement_1 (2025): 1735. https://doi.org/10.1158/1538-7445.am2025-1735.

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Background: Replication stress is a feature of the hyper-proliferation experienced by many cancers, leading to genome instability and accumulation of potentially lethal DNA damage. During their evolution, many cancer cells inactivate specific DNA-damage response pathways, placing high dependence on the pathways that remain, one of which is regulated by PKMYT1. This protein kinase prevents unscheduled G2 to M transition to allow cells the time needed for DNA repair before division. In cells that rely on PKMYT1, its inhibition forces cells to divide when they are not ready, leading to synthetic
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Alden, Stephanie Leigh, Soren Charmsaz, Madelena Brancati, et al. "Abstract 3846: The obesity paradox in immune checkpoint blockade: A pan-tumor analysis." Cancer Research 84, no. 6_Supplement (2024): 3846. http://dx.doi.org/10.1158/1538-7445.am2024-3846.

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Abstract Background: Chronic systemic inflammation mediated by pro-inflammatory cytokines serves as a major mechanism by which obesity contributes to cancer development. Paradoxically, elevated body mass (BMI) has been associated with improved outcomes after treatment with immune checkpoint inhibitors (ICIs) in many tumor types. The interplay between cytokine response and obesity after ICIs is poorly understood. To characterize underlying mechanisms, we investigated cytokine profiles in relation to obesity and clinical outcomes in patients treated with ICIs. Methods: From June 2021 to October
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Sims, Robert C., Darlene E. Fisher, Steven A. Leibo, et al. "Book Reviews." Teaching History: A Journal of Methods 13, no. 2 (1988): 80–104. http://dx.doi.org/10.33043/th.13.2.80-104.

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Michael B. Katz. Reconstructing American Education. Cambridge and London: Harvard University Press, 1987. Pp. viii, 212. Cloth, $22.50; E. D. Hirsch, Jr. Cultural Literacy: What Every American Needs to Know. Boston: Houghton Mifflin Co., 1987. Pp. xvii, 251. Cloth, $16.45; Diana Ravitch and Chester E. Finn, Jr. What Do Our 17-Year-Olds Know? A Report on the First National Assessment of History and Literature. New York: Harper & Row, 1987. Pp. ix, 293. Cloth, $15.95. Review by Richard A. Diem of The University of Texas at San Antonio. Henry J. Steffens and Mary Jane Dickerson. Writer's Guid
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Thakar, Amit, Shawn Dutkiewicz, Timothy Hoffman, Paul Joyce, and Vishal Shah. "Absence of SARS-CoV-2 in the air and on the surfaces within the school environment." Journal of Medical Microbiology 70, no. 9 (2021). http://dx.doi.org/10.1099/jmm.0.001424.

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To the best of our knowledge to date there are no scientific studies specifically investigating whether the SARS-CoV-2 virus is present in the air or on the various surfaces in the school environment. The aim of this study was to determine if SARS-CoV-2 is present on various high touch surfaces and in the air across the elementary, middle and high schools in the Chester County of Pennsylvania, USA. One hundred and fifty surface swab samples and 45 air samples were analysed for the presence of the virus. All the samples tested were negative for the presence of SARS-CoV-2. The results indicate t
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Montandon, Line, Dan Yedu Quansah, Alain Lacroix, et al. "Maternal Physical Activity, Fitness, and Body Composition in Women with Gestational Diabetes: A Prospective Study." Medicine & Science in Sports & Exercise, April 4, 2025. https://doi.org/10.1249/mss.0000000000003716.

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ABSTRACT Purpose This study aimed to 1) describe perinatal changes of physical activity (PA), physical fitness (PF), and body composition (BC) and 2) investigate prospective associations between PA and PF, and between PF and BC in metabolically high-risk women with gestational diabetes mellitus (GDM). Methods This secondary analysis of the MySweetheart trial included 211 women with GDM. Outcomes were measured at 24-32 weeks of gestational age (GA) and at 1 year postpartum. PA was measured using accelerometer and BC with Bioelectrical Impedance Analysis (fat mass (FM), fat-free mass (FFM)) or D
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Sheffels, Erin, Mariam Khalil, Kristen Hutchison, et al. "Evaluation of Post-Operative Outcomes of Femoral Neck Fracture Interventions: A Systematic Review." Geriatric Orthopaedic Surgery & Rehabilitation 15 (January 2024). http://dx.doi.org/10.1177/21514593241273326.

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Introduction Femoral neck fractures (FNF) represent a significant challenge in orthopedic practice, demanding prompt intervention to restore function and mobility in affected individuals. Numerous surgical interventions have been developed to address these fractures, including internal fixation with devices such as the Femoral Neck System (FNS, DePuy Synthes, Inc., West Chester, PA, USA). However, the optimal fixation system remains unclear. Understanding the postoperative outcomes associated with these interventions is crucial for optimizing patient care and informing treatment decisions. Sig
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Reynolds, Kirsten. "The Former Mistake." InTensions, April 1, 2009. http://dx.doi.org/10.25071/1913-5874/37333.

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When absence is disguised as excess, looking becomes a comedic performance. Architectural structures, poised in a moment between imminent collapse and perpetual construction, suggest a strangely funny and dreadful event on the verge of becoming. Useless or interstitial spaces invited peeping, whimsical, biomorphic creatures appear to pause in the midst of creeping, oozing or watching and additional elements, furtively placed among the architecture, intensify the potential for a narrative. My work activates the agency of that which evades certain knowing, experienced at the intersection of lang
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"11.B. Round table: From Science to Policy Making: Lessons learned from ASPHER’s COVID-19 Task Force." European Journal of Public Health 32, Supplement_3 (2022). http://dx.doi.org/10.1093/eurpub/ckac129.692.

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Abstract ASPHER, the Association of Public Health Schools in the European Region, convened a COVID-19 Task Force (TF) at the start of the pandemic. The TF has involved over 60 experts, 30 member schools, more than 20 countries across four continents, supported by young professionals (YPs). The COVID-19 TF became a unique expert forum for mutual support, sharing, reviewing, and presenting evidence on epidemiological, technical, societal, and political dimensions of the COVID-19 pandemic across Europe. Working with European and national health authorities and non-governmental organisations (NGOs
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Schneider, Friedemann, Fabian Geir, Christian Koidl, Luise Gehrer, Armin Runer, and Rohit Arora. "Retrospective evaluation of radiological and clinical outcomes after surgical treatment of proximal femur fractures utilizing TFNA." Archives of Orthopaedic and Trauma Surgery, December 2, 2022. http://dx.doi.org/10.1007/s00402-022-04704-x.

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Abstract Introduction The aim of this study was to evaluate the clinical and radiological outcomes of patients treated with the TFN-Advanced™ Proximal Femoral Nailing system (TFNA¸ DePuy Synthes, West Chester, PA) including intra- and postoperative complications. Materials and methods All patients with an acute proximal femur fracture consequently treated with a TFNA between September 2014 and December 2018 were evaluated. Clinical and radiological data were assessed for intra- and postoperative complications, including treatment failure. In addition, intra- and postoperative X-rays were used
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14

Attwa, Mohamed W., Haitham AlRabiah, Ali S. Abdelhameed, and Adnan A. Kadi. "Assessment of the in vitro metabolic stability of CEP-37440, a selective FAK/ALK inhibitor, in HLMs using fast UPLC–MS/MS method: in silico metabolic lability and DEREK alerts screening." Frontiers in Chemistry 12 (September 26, 2024). http://dx.doi.org/10.3389/fchem.2024.1323738.

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IntroductionCEP-37440 was synthesized and supplied by the research and development division of Teva Branded Pharmaceutical Products (West Chester, PA, United States). CEP-37440 represents a newly developed compound that exhibits selectivity inhibition of Focal Adhesion Kinase and Anaplastic Lymphoma Kinase FAK/ALK receptors, demonstrating novel characteristics as an orally active inhibitor. The simultaneous inhibition of ALK and FAK can effectively address resistance and enhance the therapeutic efficacy against tumors through a synergistic mechanism.MethodsThe objective of this research was to
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Sulz, David. "News, Awards, and Announcements." Deakin Review of Children's Literature 4, no. 1 (2014). http://dx.doi.org/10.20361/g2x31f.

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Probably, you are enjoying the wonderful summer by reading books, books, and more books. We, too, are busy reading and enjoying summer so the news this time around is brief.In June, Barbro Lindgren was awarded the Astrid Lindgren Memorial award at the Stockholm Concert Hall. This award, founded in 2002 by the Swedish Arts Council, is the world’s largest award for children’s and young adult literature at 5 million SEK (about $700,000 CAD). If it sounds suspicious that a Swedish writer with the same surname as the Swedish award’s Swedish namesake has won, rest assured that it truly is open to th
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Brien, Donna Lee. "Fat in Contemporary Autobiographical Writing and Publishing." M/C Journal 18, no. 3 (2015). http://dx.doi.org/10.5204/mcj.965.

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At a time when almost every human transgression, illness, profession and other personal aspect of life has been chronicled in autobiographical writing (Rak)—in 1998 Zinsser called ours “the age of memoir” (3)—writing about fat is one of the most recent subjects to be addressed in this way. This article surveys a range of contemporary autobiographical texts that are titled with, or revolve around, that powerful and most evocative word, “fat”. Following a number of cultural studies of fat in society (Critser; Gilman, Fat Boys; Fat: A Cultural History; Stearns), this discussion views fat in socio
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Sears, Cornelia, and Jessica Johnston. "Wasted Whiteness: The Racial Politics of the Stoner Film." M/C Journal 13, no. 4 (2010). http://dx.doi.org/10.5204/mcj.267.

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We take as our subject what many would deem a waste of good celluloid: the degraded cultural form of the stoner film. Stoner films plot the experiences of the wasted (those intoxicated on marijuana) as they exhibit wastefulness—excessiveness, improvidence, decay—on a number of fronts. Stoners waste time in constantly hunting for pot and in failing to pursue more productive activity whilst wasted. Stoners waste their minds, both literally, if we believe contested studies that indicate marijuana smoking kills brains cells, and figuratively, in rendering themselves cognitively impaired. Stoners w
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Foster, Kevin. "True North: Essential Identity and Cultural Camouflage in H.V. Morton’s In Search of England." M/C Journal 20, no. 6 (2017). http://dx.doi.org/10.5204/mcj.1362.

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When the National Trust was established in 1895 its founders, Canon Rawnsley, Sir Robert Hunter and Octavia Hill, were, as Cannadine notes, “primarily concerned with preserving open spaces of outstanding natural beauty which were threatened with development or spoliation.” This was because, like Ruskin, Morris and “many of their contemporaries, they believed that the essence of Englishness was to be found in the fields and hedgerows, not in the suburbs and slums” (Cannadine 227). It was important to protect these sites of beauty and historical interest from development not only for what they w
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Beyer, Sue. "Fantasyland Autofiction." M/C Journal 27, no. 5 (2024). http://dx.doi.org/10.5204/mcj.3104.

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This essay explores a return to hope and romanticism by contemporary artists looking at themes of fantasy worlds and mapping imaginary lands as a type of autofiction. These fantasylands are created in collaboration with hallucinating machine learning platforms, as a tool for contemporary art-making. Seen through the framework of Metamodernism, how does AI hallucination contribute to Metamodern structure of feeling? AI, as part of the metacrisis, places society and culture in a type of no man’s land or in-between, where rapid and unchecked advancements in machine learning and generative technol
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