Thematische Bibliographien / Circadian clock

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Auswahl der wissenschaftlichen Literatur zum Thema „Circadian clock“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 25. Juli 2025

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Zeitschriftenartikel zum Thema "Circadian clock"

Xiao, Yangbo, Ye Yuan, Mariana Jimenez, Neeraj Soni, and Swathi Yadlapalli. "Clock proteins regulate spatiotemporal organization of clock genes to control circadian rhythms." Proceedings of the National Academy of Sciences 118, no. 28 (2021): e2019756118. http://dx.doi.org/10.1073/pnas.2019756118.

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Circadian clocks regulate ∼24-h oscillations in gene expression, behavior, and physiology. While the genetic and molecular mechanisms of circadian rhythms are well characterized, what remains poorly understood are the intracellular dynamics of circadian clock components and how they affect circadian rhythms. Here, we elucidate how spatiotemporal organization and dynamics of core clock proteins and genes affect circadian rhythms in Drosophila clock neurons. Using high-resolution imaging and DNA-fluorescence in situ hybridization techniques, we demonstrate that Drosophila clock proteins (PERIOD

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Costello, Hannah M., and Michelle L. Gumz. "Circadian Rhythm, Clock Genes, and Hypertension: Recent Advances in Hypertension." Hypertension 78, no. 5 (2021): 1185–96. http://dx.doi.org/10.1161/hypertensionaha.121.14519.

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Accumulating evidence suggests that the molecular circadian clock is crucial in blood pressure (BP) control. Circadian rhythms are controlled by the central clock, which resides in the suprachiasmatic nucleus of the hypothalamus and peripheral clocks throughout the body. Both light and food cues entrain these clocks but whether these cues are important for the circadian rhythm of BP is a growing area of interest. The peripheral clocks in the smooth muscle, perivascular adipose tissue, liver, adrenal gland, and kidney have been recently implicated in the regulation of BP rhythm. Dysregulation o

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Clark, Amelia M., and Brian J. Altman. "Circadian control of macrophages in the tumor microenvironment." Journal of Immunology 208, no. 1_Supplement (2022): 165.06. http://dx.doi.org/10.4049/jimmunol.208.supp.165.06.

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Abstract Introduction All leukocytes tested to date have functional circadian clocks, and nearly every arm of the immune response is subject to circadian regulation. Circadian clocks instruct the time-of-day-dependent, rhythmic expression of genes in a tissue- and cell-specific manner. In macrophages (mΦs), the circadian clock regulates several factors that are critical to executing effective immune responses. Tumor-associated mΦs are major contributors to immune suppression in the tumor microenvironment (TME). Evidence suggests that metabolically stressful factors in the TME such as acidic pH

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Shakhmantsir, Iryna, and Amita Sehgal. "Splicing the Clock to Maintain and Entrain Circadian Rhythms." Journal of Biological Rhythms 34, no. 6 (2019): 584–95. http://dx.doi.org/10.1177/0748730419868136.

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Circadian clocks drive daily rhythms of physiology and behavior in multiple organisms and synchronize these rhythms to environmental cycles of light and temperature. The basic mechanism of the clock consists of a transcription-translation feedback loop, in which key clock proteins negatively regulate their own transcription. Although much of the focus with respect to clock mechanisms has been on the regulation of transcription and on the stability and activity of clock proteins, it is clear that other regulatory processes also have to be involved to explain aspects of clock function. Here, we

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Myung, Jihwan, Mei-Yi Wu, Chun-Ya Lee, et al. "The Kidney Clock Contributes to Timekeeping by the Master Circadian Clock." International Journal of Molecular Sciences 20, no. 11 (2019): 2765. http://dx.doi.org/10.3390/ijms20112765.

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The kidney harbors one of the strongest circadian clocks in the body. Kidney failure has long been known to cause circadian sleep disturbances. Using an adenine-induced model of chronic kidney disease (CKD) in mice, we probe the possibility that such sleep disturbances originate from aberrant circadian rhythms in kidney. Under the CKD condition, mice developed unstable behavioral circadian rhythms. When observed in isolation in vitro, the pacing of the master clock, the suprachiasmatic nucleus (SCN), remained uncompromised, while the kidney clock became a less robust circadian oscillator with

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Fu, Minnie, and Xiaoyong Yang. "The sweet tooth of the circadian clock." Biochemical Society Transactions 45, no. 4 (2017): 871–84. http://dx.doi.org/10.1042/bst20160183.

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The endogenous circadian clock is a key regulator of daily metabolic processes. On the other hand, circadian clocks in a broad range of tissues can be tuned by extrinsic and intrinsic metabolic cues. The bidirectional interaction between circadian clocks and metabolism involves both transcriptional and post-translational mechanisms. Nuclear receptors exemplify the transcriptional programs that couple molecular clocks to metabolism. The post-translational modifications of the core clock machinery are known to play a key role in metabolic entrainment of circadian clocks. O-linked N-acetylglucosa

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Wu, Yiyang. "The Evolutionary Pathways of the Circadian Rhythms through Phylogenetical Analysis of Basal Circadian Genes." Highlights in Science, Engineering and Technology 54 (July 4, 2023): 367–76. http://dx.doi.org/10.54097/hset.v54i.9795.

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Circadian rhythm is the endogenous clock in organisms that regulates the performance of various physiological and metabolic events in accordance with the periodic oscillating changes in the environment, especially the periodic light-dark cycle. The clock has endowed organisms with the ability in anticipating environmental changes allowing them to adjust their survival strategies accordingly, promoting their selective fitness. However, the evolutionary path and the emergence of such an intricate and vital system remain elusive. The article aims to analyse the molecular architecture and componen

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Li, Meina, Lijun Cao, Musoki Mwimba, et al. "Comprehensive mapping of abiotic stress inputs into the soybean circadian clock." Proceedings of the National Academy of Sciences 116, no. 47 (2019): 23840–49. http://dx.doi.org/10.1073/pnas.1708508116.

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The plant circadian clock evolved to increase fitness by synchronizing physiological processes with environmental oscillations. Crop fitness was artificially selected through domestication and breeding, and the circadian clock was identified by both natural and artificial selections as a key to improved fitness. Despite progress in Arabidopsis, our understanding of the crop circadian clock is still limited, impeding its rational improvement for enhanced fitness. To unveil the interactions between the crop circadian clock and various environmental cues, we comprehensively mapped abiotic stress

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Bailey, Shannon M. "Emerging role of circadian clock disruption in alcohol-induced liver disease." American Journal of Physiology-Gastrointestinal and Liver Physiology 315, no. 3 (2018): G364—G373. http://dx.doi.org/10.1152/ajpgi.00010.2018.

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The detrimental health effects of excessive alcohol consumption are well documented. Alcohol-induced liver disease (ALD) is the leading cause of death from chronic alcohol use. As with many diseases, the etiology of ALD is influenced by how the liver responds to other secondary insults. The molecular circadian clock is an intrinsic cellular timing system that helps organisms adapt and synchronize metabolism to changes in their environment. The clock also influences how tissues respond to toxic, environmental, and metabolic stressors, like alcohol. Consistent with the essential role for clocks

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Helfrich-Förster, Charlotte, Michael N. Nitabach, and Todd C. Holmes. "Insect circadian clock outputs." Essays in Biochemistry 49 (June 30, 2011): 87–101. http://dx.doi.org/10.1042/bse0490087.

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Insects display an impressive variety of daily rhythms, which are most evident in their behaviour. Circadian timekeeping systems that generate these daily rhythms of physiology and behaviour all involve three interacting elements: the timekeeper itself (i.e. the clock), inputs to the clock through which it entrains and otherwise responds to environmental cues such as light and temperature, and outputs from the clock through which it imposes daily rhythms on various physiological and behavioural parameters. In insects, as in other animals, cellular clocks are embodied in clock neurons capable o

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Dissertationen zum Thema "Circadian clock"

Brettschneider, Christian. "The cyanobacterial circadian clock." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16385.

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Cyanobakterien zŠhlen zu den Šltesten Lebewesen auf der Erde. Diese Bakterien, auch Blaualgen genannt, trugen wesentlich zur Sauerstoffanreicherung der Erde bei, da sie eine ausgeprŠgte FŠhigkeit zur Photosynthese besitzen. Der produzerte Sauerstoff der Photosynthese hemmt jedoch eine weitere AktivitŠt von Cyanobakterien, die Stickstofffixierung. Um die Hemmung zu vermeiden, werden diese AktivitŠten zeitlich getrennt und optimal dem tŠglichen Hell-Dunkel-Rhythmus angepasst. Ein evolutionŠrer Vorteil wird erzielt, wenn der Organismus diesen Rhythmus antizipiert und sich darauf vorbereitet. Aus

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Smith, Karen Lynn. "Entrainment of the circadian clock." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624358.

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Galvanin, Silvia. "Circadian Clock Study Through Frequency-Encoded Entrainment Stimulations." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3422301.

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Circadian clocks are intrinsic, time-tracking systems that enable organisms to maintain their physiological state and their synchrony with the 24-hour rotation of the Earth, by partitioning behavioural and metabolic processes according to time of day within each tissue. They are entrained to the external environment by light/dark cycles and by food timing, which act as clock synchronizers. Emerging evidence suggests that circadian regulation is intimately linked to metabolic homeostasis and that dysregulation of circadian rhythms can contribute to disease. Conversely, metabolic signals also fe

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Gegnaw, Shumet T. "The connection between circadian clock impairment and retinal disease." Electronic Thesis or Diss., Strasbourg, 2023. http://www.theses.fr/2023STRAJ120.

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Cette thèse a étudié comment une dérégulation de l'horloge circadienne, qui n'avait pas été clairement associée à une maladie rétinienne jusqu'à présent, pourrait contribuer à la dégénérescence et influencer le développement et la fonction de la rétine. L'inactivation spécifique du gène horloge Bmal1 (rod-Bmal1KO) dans la lignée de souris portant la mutation P23H de la rhodopsine aggrave les symptômes de dégénérescence rétinienne, tels que la réduction de la réponse ERG et la perte de bâtonnets, induits par la seule mutation P23H. Ces observations ont été corroborées par l'analyse RNA-Seq qui

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Gesto, João Silveira Moledo. "Circadian clock genes and seasonal behaviour." Thesis, University of Leicester, 2011. http://hdl.handle.net/2381/10266.

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Circadian and photoperiodic phenomena serve to organize the temporal pattern of various biological processes. While the former generates endogenous daily rhythms, the latter is related to seasonality. In Drosophila melanogaster, the gene timeless (tim) encodes a cardinal component of the circadian clock and also contributes to photoperiodism, which is observed as an adult reproductive diapause. In this work, natural tim variants were examined for diapause across different temperatures and photoperiods. The newly derived allele, ls-tim, exhibited consistently higher diapause levels than the anc

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Curran, Jack. "Ageing and the Drosophila circadian clock." Thesis, University of Bristol, 2019. http://hdl.handle.net/1983/7b02ec7c-f6a2-4640-b50f-ce97a66a5a11.

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It is well established that elderly individuals have increased difficulty sleeping at night combined with falling asleep and waking up earlier. Although these age-related declines in circadian output are clearly observable in activity recordings of laboratory animals, the underlying changes in molecular and neuronal activity remain unknown. The fruit fly, Drosophila melanogaster, has long been used as a model for studying the circadian system and for ageing research. In this thesis Drosophila was used as a model to study the effect of ageing on circadian and sleep behaviour. Circadian behaviou

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Beynon, Amy Louise. "Neuroimmune modulation of the circadian clock." Thesis, Swansea University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678517.

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Jaeger, Cassie Danielle. "Chronic Circadian Misalignment Disrupts the Circadian Clock and Promotes Metabolic Syndrome." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/1081.

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Obesity, metabolic syndrome, and diabetes represent a major source of morbidity and mortality in the United States and worldwide. Chronic misalignment of an organism’s internal circadian clock with diurnal, cyclic changes in the external environment, prevalent in professions that require shift work, contributes significantly to Type 2 Diabetes development. Experimentally, only short-term models of circadian disruption have been explored. Therefore, the goal of this study was to establish an animal model of chronic circadian disruption, which would more closely mimic the harmful misalignment as

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Cotter, Sean. "Characterisation of the circadian clock in barley." Thesis, University of Liverpool, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548780.

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Reddy, Akhilesh Basi. "Molecular Neurobiology of the mammalian circadian clock." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619684.

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Bücher zum Thema "Circadian clock"

Albrecht, Urs, ed. The Circadian Clock. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1262-6.

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Rizvi, Syed Ibrahim, and Gaurav Majumdar. Circadian Clock and Aging. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-6695-6.

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Engmann, Olivia, and Marco Brancaccio, eds. Circadian Clock in Brain Health and Disease. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-81147-1.

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Björn, Lemmer, and Rensing Ludger, eds. From the biological clock to chronopharmacology. Medpharm, 1996.

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Ewa, Kulczykowska, Popek Wlodzimierz, and Kapoor B. G, eds. Biological clock in fish. Science Publishers, 2010.

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Csernus, Valér. The avian pineal gland: A model of the biological clock. Akadémiai Kiadó, 2004.

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Hirota, Tsuyoshi, Megumi Hatori, and Satchidananda Panda, eds. Circadian Clocks. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2577-4.

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Brown, Steven A., ed. Circadian Clocks. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-0381-9.

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Kramer, Achim, and Martha Merrow, eds. Circadian Clocks. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-25950-0.

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S, Takahashi Joseph, Turek Fred W, and Moore Robert Y, eds. Circadian clocks. Kluwer Academic/Plenum Publishers, 2001.

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Buchteile zum Thema "Circadian clock"

Levesque, Roger J. R. "Circadian Clock." In Encyclopedia of Adolescence. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-1695-2_460.

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Thiriet, Marc. "Circadian Clock." In Control of Cell Fate in the Circulatory and Ventilatory Systems. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-0329-6_5.

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Levesque, Roger J. R. "Circadian Clock." In Encyclopedia of Adolescence. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-33228-4_460.

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Michel, Stephan, Gene D. Block, and Johanna H. Meijer. "The Aging Clock." In Circadian Medicine. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118467831.ch22.

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Daniel Rudic, R. "The Cardiovascular Clock." In Circadian Medicine. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118467831.ch8.

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Herzog, Erik D., and Paul H. Taghert. "Circadian Neural Networks." In The Circadian Clock. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1262-6_8.

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Daan, Serge. "A History of Chronobiological Concepts." In The Circadian Clock. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1262-6_1.

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Feillet, Céline, and Urs Albrecht. "Clocks, Brain Function, and Dysfunction." In The Circadian Clock. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1262-6_10.

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d’Eysmond, Thomas, and Felix Naef. "Systems Biology and Modeling of Circadian Rhythms." In The Circadian Clock. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1262-6_11.

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Ripperger, Jürgen A., and Steven A. Brown. "Transcriptional Regulation of Circadian Clocks." In The Circadian Clock. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1262-6_2.

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Konferenzberichte zum Thema "Circadian clock"

Lyons, Jeri-Anne, Ann Liebert, Roberta Chow, Peter Bian, Chunling Huang, and Carol Pollock. "Circadian clock modulation as a mechanism of PBM treatment effects." In Mechanisms of Photobiomodulation Therapy XIX, edited by James D. Carroll, Ann Liebert, and Jeri-Anne Lyons. SPIE, 2025. https://doi.org/10.1117/12.3062675.

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AXMANN, ILKA M., STEFAN LEGEWIE, and HANSPETER HERZEL. "A MINIMAL CIRCADIAN CLOCK MODEL." In Proceedings of the 7th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2007). IMPERIAL COLLEGE PRESS, 2007. http://dx.doi.org/10.1142/9781860949920_0006.

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O’Reilly, Steven. "04.22 Circadian clock and fibrosis." In 37th European Workshop for Rheumatology Research 2–4 March 2017 Athens, Greece. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2016-211051.22.

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Naik, A., K. Forrest, S. Gavronski, U. Valekunja, A. Reddy, and S. Sengupta. "Circadian Clock Modulates Lung Repair and Regeneration." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4525.

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Lewis, R. D. "A feedback model for an insect circadian clock." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.95054.

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Kurosawa, Gen, Kazuyuki Aihara, and Yoh Iwasa. "Bifurcation analyses in the cyanobacterial circadian clock model." In 2006 IEEE/NLM Life Science Systems and Applications Workshop. IEEE, 2006. http://dx.doi.org/10.1109/lssa.2006.250394.

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Sorkin, Maria. "A Comprehensive Interactome for the Arabidopsis Circadian Clock." In ASPB PLANT BIOLOGY 2020. ASPB, 2020. http://dx.doi.org/10.46678/pb.20.989669.

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Figueiredo, Erika Ciconelli de, and Maria Augusta Justi Pisani. "Office building typologies and circadian potential." In XVII ENCONTRO NACIONAL DE CONFORTO NO AMBIENTE CONSTRUÍDO. ANTAC, 2023. http://dx.doi.org/10.46421/encac.v17i1.3878.

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Circadian rhythms are internal manifestations of the solar day that allow adaptations to environmental-temporal changes. Mood disorders are often associated with disrupted circadian clock-controlled responses, whereas circadian rhythm disruption is correlated to jet lag, night-shift work, or to exposure to artificial light at night. Modern lifestyle patterns lead to circadian rhythm disruption, and it results in several diseases. Circadian rhythm disruption is one of the factors most often investigated, besides smoking, diet, fatigue and quality sleep, increased body mass index and obesity. La

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Merlin, Christine. "Circadian clock control of the monarch butterfly seasonal migration." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.92863.

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Foo, Mathias, Hee Young Yoo, and Pan-Jun Kim. "System identification of circadian clock in plant Arabidopsis thaliana." In 2013 13th International Conference on Control, Automaton and Systems (ICCAS). IEEE, 2013. http://dx.doi.org/10.1109/iccas.2013.6703901.

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Berichte der Organisationen zum Thema "Circadian clock"

Johnson, Carl H. Cell-permeable Circadian Clock Proteins. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada405529.

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Czeisler, Charles A., and Laura K. Barger. Clinical Trial of Exercise on Circadian Clock Resetting. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada387100.

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Casey, Therese, Sameer J. Mabjeesh, Avi Shamay, and Karen Plaut. Photoperiod effects on milk production in goats: Are they mediated by the molecular clock in the mammary gland? United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7598164.bard.

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US scientists, Dr. Theresa Casey and Dr. Karen Plaut, collaborated with Israeli scientists, Dr. SameerMabjeesh and Dr. AviShamay to conduct studies proposed in the BARD Project No. US-4715-14 Photoperiod effects on milk production in goats: Are they mediated by the molecular clock in the mammary gland over the last 3 years. CLOCK and BMAL1 are core components of the circadian clock and as heterodimers function as a transcription factor to drive circadian-rhythms of gene expression. Studies of CLOCK-mutant mice found impaired mammary development in late pregnancy was related to poor lactation p

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Van Cauter, Eve. Phase-Shifting Effects of Light and Activity on the Human Circadian Clock. Defense Technical Information Center, 1994. http://dx.doi.org/10.21236/ada281204.

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Van Cauter, Eve. Phase-Shifting Effect of Light and Exercise on the Human Circadian Clock. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada253012.

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Van Cauter, Eve, Jeppe Sturis, Maria M. Byrne, et al. Phase-Shifting Effect of Light and Exercise on the Human Circadian Clock. Defense Technical Information Center, 1993. http://dx.doi.org/10.21236/ada265732.

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Van Cauter, Eve. Phase Shifting Effects of Light and Activity on the Human Circadian Clock. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada337545.

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Gauger, Michele A. Determining the Effect of Cryptochrome Loss and Circadian Clock Disruption on Tumorigenesis in Mice. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada435115.

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Gillette, Martha. AASERT-92 Augmentation of Research Training in Chronobiology: Regulation of the Mammalian Circadian Clock by Neurotransmitters. Defense Technical Information Center, 1994. http://dx.doi.org/10.21236/ada288243.

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Wagner, D. Ry, Eliezer Lifschitz, and Steve A. Kay. Molecular Genetic Analysis of Flowering in Arabidopsis and Tomato. United States Department of Agriculture, 2002. http://dx.doi.org/10.32747/2002.7585198.bard.

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The primary objectives for the US lab included: the characterization of ELF3 transcription and translation; the creation and characterization of various transgenic lines that misexpress ELF3; defining genetic pathways related to ELF3 function regulating floral initiation in Arabidopsis; and the identification of genes that either interact with or are regulated by ELF3. Light quality, photoperiod, and temperature often act as important and, for some species, essential environmental cues for the initiation of flowering. However, there is relatively little information on the molecular mechanisms

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