Auswahl der wissenschaftlichen Literatur zum Thema „COMBINATORIAL THERAPY“

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Zeitschriftenartikel zum Thema "COMBINATORIAL THERAPY"

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Stritzker, J., and A. A. Szalay. "Single-agent combinatorial cancer therapy." Proceedings of the National Academy of Sciences 110, no. 21 (2013): 8325–26. http://dx.doi.org/10.1073/pnas.1305832110.

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Baust, J. G. "Cryoablation: An Emergent Combinatorial Therapy." Cryobiology 92 (February 2020): 272. http://dx.doi.org/10.1016/j.cryobiol.2019.11.010.

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Koh, Yoon Woo. "Combinatorial Targeted Therapy in Thyroid Cancer." Korean Journal of Otorhinolaryngology-Head and Neck Surgery 53, no. 4 (2010): 203. http://dx.doi.org/10.3342/kjorl-hns.2010.53.4.203.

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Mittra, Arjun, and Debu Tripathy. "Looking ahead to rational combinatorial therapy." Community Oncology 9, no. 2 (2012): 40–41. http://dx.doi.org/10.1016/j.cmonc.2012.02.002.

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Sabbatino, Francesco, Yangyang Wang, Ravin Poudel, et al. "Novel combinatorial therapy for pancreatic adenocarcinoma." Journal of the American College of Surgeons 217, no. 3 (2013): S137. http://dx.doi.org/10.1016/j.jamcollsurg.2013.07.319.

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Anitha, A., S. Maya, Amal J. Sivaram, U. Mony, and R. Jayakumar. "Combinatorial nanomedicines for colon cancer therapy." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8, no. 1 (2015): 151–59. http://dx.doi.org/10.1002/wnan.1353.

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Vojvodic, Sladjana, Gabor Katona, and Miroslav Sarac. "Combinatorial pharmacogenomic test for successful antidepressant treatment of a major depressive disorder." Medical review 74, no. 3-4 (2021): 117–22. http://dx.doi.org/10.2298/mpns2104117v.

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Introduction. The combinatorial pharmacogenomic test has shown the potential to predict antidepressant response, tolerability, selection, and dosage in the treatment of a major depressive disorder. A case of successful management of antidepressant therapy adjustment is reported by using the combinatorial pharmacogenomic test. Case Report. A 53-year old man, severely disabled due to a rare genetic disease, Usher syndrome type 3, was treated with numerous antidepressants. However, episodes of major depression recurred, along with frequent suicidal thoughts. A combinatorial pharmacogenomic test w
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Kushwah, Atar Singh, Rajnikant Mishra, Ashwin Kumar Shukla, and Monisha Banerjee. "Combinatorial therapy of Cynodon dactylon and Metformin with Cisplatin in cervical cancer." Journal of Scientific Research 66, no. 04 (2022): 35–41. http://dx.doi.org/10.37398/jsr.2022.660406.

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Cisplatin based chemoradiation (CRT) is the standard treatment for cervical cancer, which controls tumor growth and improves the overall survival of patients. However, patients undergoing chemo-radiation show widespread toxicities which may be either early or late. There is a constant effort to improve cancer therapy and overcome current challenges in cervical cancer by developing a combinatorial drug therapy using phytocompounds. In the present study, we review the combinatorial therapy of Cynodon dactylon and metformin with cisplatin as an alternative therapy for cervical cancer. During freq
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Sabei, Fahad Y., Olena Taratula, Hassan A. Albarqi, et al. "A targeted combinatorial therapy for Ewing's sarcoma." Nanomedicine: Nanotechnology, Biology and Medicine 37 (October 2021): 102446. http://dx.doi.org/10.1016/j.nano.2021.102446.

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Kwong, L. N., and M. A. Davies. "Targeted therapy for melanoma: rational combinatorial approaches." Oncogene 33, no. 1 (2013): 1–9. http://dx.doi.org/10.1038/onc.2013.34.

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Dissertationen zum Thema "COMBINATORIAL THERAPY"

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CATTANEO, STEFANO. "Combinatorial gene therapy for epilepsy." Doctoral thesis, Università Vita-Salute San Raffaele, 2022. http://hdl.handle.net/20.500.11768/128275.

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Epilepsy is a neurological disease characterized by a persistent predisposition to generate seizures, that affects about 1% of the world population. About 30% of epileptic patients are drug-resistant, thus refractory to currently available anti-epileptic drugs (AEDs). Less than 10% of these drug-resistant patients are eligible for resective brain surgery, often due to generalized or multiple epileptic foci, or due to proximity of the epileptic focus to eloquent brain areas. Therefore, gene therapy may represent a doable approach for the unmet medical need of these patients. Neuropeptide Y (NP
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Pace, Emily A. "Investigating combinatorial ligand addiction provides insights into rational drug combinations in cancer therapy." Thesis, Boston University, 2012. https://hdl.handle.net/2144/34647.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Cancer, the second most common cause of death in the United States, is a collection of diseases caused by uncontrolled cell growth and metastasis. The main treatment for cancer is chemotherapy, which generall
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Tavallai, Mehrad. "INTRODUCING NOVEL COMBINATORIAL TARGETED THERAPIES IN MULTIPLE TYPES OF CANCER." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4088.

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The cancers of liver, colon and breast are amongst the top five most prevalent and most fatal worldwide. As the Raf/MEK/ERK pathway is frequently deregulated in hepatocellular carcinoma (HCC), sorafenib, a Raf kinase inhibitor, became the first systemic therapy approved for the treatment of patients with HCC. However, sorafenib only produced modest effects with low response rates in the clinic. Similarly, regorafenib, which was approved for the treatment of metastatic colorectal cancer (CRC), has had a poor response rate in the clinic. Since phosphodiesterase type 5 has been reported to be ove
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Valencia, Pedro M. (Pedro Miguel). "A microfluidic platform for combinatorial synthesis and optimization of targeted polymeric nanoparticles for cancer therapy." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/79197.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, February 2013.<br>"November 2012." Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>The use of nanotechnology to engineer drug delivery vehicles comprised of controlled release polymers with targeting molecules has the potential to revolutionize cancer therapy, among other diseases. Although a myriad of nanotherapeutics have been developed at the bench side, many of them stay at the research stage due to their complexity and difficulty in their optimization. A key challenge fo
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MAROCCHI, FEDERICA. "FUNCTIONAL DROP-OUT SCREENINGS IDENTIFY ACTIONABLE VULNERABILITIES TO HALT MELANOMA GROWTH AND METASTASIS FORMATION." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/820408.

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Advanced and metastatic melanoma prognosis is poor. Recent approval of targeted and immune therapies markedly improved overall survival rates, but nevertheless, the majority of patients experience recurrence and resistance, as well as treatment discontinuation due to severe toxicities. To explore new promising therapeutic approach in melanoma, I made use of our cohort of metastatic melanoma patient-derived xenografts (PDXs) to perform drop-out genetic screens, by means of a shRNA library targeting actionable genes, for which drugs are already available and can be repurposed for melanoma treatm
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Mary, Bareford. "Sorafenib enhances pemetrexed-induced cytotoxicity through and autophagy-dependent mechanism in cancer cells." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2870.

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Acquired cellular resistance to traditional chemotherapeutics is a common obstacle in the treatment of most cancer cell types. This resistance occurs as a result of changes in the underlying molecular mechanisms of disease progression. The development of novel chemotherapeutic approaches designed to enhance the efficacy of protypical anti-cancer drugs is important in order to overcome this issue. Such approaches will aid in understanding the biomolecular phenomena responsible for drug resistance and disease progression. Combining signaling pathway inhibitors has become an effective strategy fo
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KUMAR, SUNIL. "COMBINATORIAL THERAPY FOR TUMOR TREATMENT." Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/20430.

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Cancer is a complex and multifaceted disease that continues to pose a significant challenge to global health. As the second leading cause of death worldwide. Early detection and noninvasive techniques of detecting cancer are necessary to improve treatment outcomes, save lives and improve the quality of life. Biopsies of tumors are often expensive and invasive and raise the risk of serious complications like infection, excessive bleeding, and puncture damage to nearby tissues and organs. Early detection biomarkers are often variably expressed in different patients and may even be bel
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Rhee, Younghwa. "Efficacy of losartan and growth hormone combinatorial therapy in DyW mice." Thesis, 2015. https://hdl.handle.net/2144/16344.

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Merosin-deficient CMD type 1A (MDC1A) is the second most common form of congenital muscular dystrophy (CMD) that presents at or near birth. MDC1A is caused by a mutation in the LAMA2 gene which encodes a protein called laminin-2. The clinical manifestations of MDC1A include profound muscle weakness, muscle hypotonia, loss of independent ambulation, and respiratory failure. There is still no cure or effective treatment available for MDC1A patients. In this study we use the Lama2dyW (DyW) mouse model which shares analogous phenotypes with the MDC1A disease in humans. To this point, therapy de
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JAIN, SHALEEN. "PREPARATION OF TUMOR TARGETING COMBINATORIAL THERAPY USING NANOPARTICLE CONJUGATED NATURAL COMPOUNDS." Thesis, 2020. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18150.

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Cancer, a multifactorial disease, caused by several genetic and environmental factors and their interactions in which normal cells become progressively transformed to malignant cells, is currently the most studied topic. Numerous receptors and pathways have been identified for cancer that play a crucial role in its progression. Natural compounds obtained from various medicinal plants have shown a promising potential in targeting cancer in multiple ways. In the present project we are exploring the design of a combinatorial cancer therapy. At first, different bioactive compounds were scree
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Bao, Xuhui. "Immunotoxin Monotherapy and Combinatorial Therapy With Immune Checkpoint Inhibitors for Malignant Brain Tumors." Diss., 2016. http://hdl.handle.net/10161/13365.

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<p>Glioblastoma is the most common and aggressive malignant brain tumor among all primary brain and central nervous system (CNS) tumors. The median survival time for glioblastoma patients given the current standard of care treatment (surgery, radiation, and chemotherapy) is less than 15 months. Medulloblastoma is another major malignant brain tumor that most frequently occurs in children. Although recent advances in surgery, radiotherapy, and chemotherapy have led to an increase in 5-year survival rates of medulloblastoma patients, treatment-related toxicity often has a major impact on long-te
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Bücher zum Thema "COMBINATORIAL THERAPY"

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Ganai, Shabir Ahmad. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8179-3.

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1966-, Seeberger Peter H., ed. Solid support oligosaccharide synthesis and combinatorial carbohydrate libraries. Wiley, 2001.

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Ganai, Shabir Ahmad. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore Pte. Limited, 2020.

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Ganai, Shabir Ahmad. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore Pte. Limited, 2021.

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Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries. Wiley & Sons Canada, Limited, John, 2004.

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Andersson, Patrik, and Christian Ostheimer, eds. Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88963-161-2.

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Atta-ur-Rahman and M. Iqbal Choudhary, eds. Frontiers in Cardiovascular Drug Discovery: Volume 4. BENTHAM SCIENCE PUBLISHERS, 2019. http://dx.doi.org/10.2174/97816810839951180401.

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Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The fourth volume of the series cov
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Kahn, Michael. High Throughput Screening for Novel Anti-Inflammatories. Birkhauser Verlag, 2012.

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Kahn, Michael. High Throughput Screening for Novel Anti-Inflammatories (Progress in Inflammation Research). Birkhauser, 2000.

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Kahn, Michael. High Throughput Screening for Novel Anti-Inflammatories. Birkhäuser, 2012.

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Buchteile zum Thema "COMBINATORIAL THERAPY"

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Dalasanur Nagaprashantha, Lokesh. "Combinatorial Cancer Therapy." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_7158-7.

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Nagaprashantha, Lokesh Dalasanur. "Combinatorial Cancer Therapy." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46875-3_7158.

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Winbanks, Catherine E., and Paul Gregorevic. "Combinatorial Gene Therapy Strategies for Treating Muscular Dystrophies." In Muscle Gene Therapy. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1207-7_8.

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Rothenberg, S. Michael, Joan Fisher, David Zapol, et al. "Intracellular Combinatorial Chemistry with Peptides in Selection of Caspase-like Inhibitors." In Gene Therapy. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72160-1_18.

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Banerjee, Ena Ray. "Novel Combinatorial Probiotics in Therapy and Prophylaxis." In Perspectives in Translational Research in Life Sciences and Biomedicine. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5870-7_3.

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Mangla, Bharti, Pankaj Kumar, Kamya Goyal, Kanchan Kohli, and Shammy Jindal. "Breast Cancer Therapy by Combinatorial Herbo-Synthetic Nanocarrier." In Bioactive-Loaded Nanomedicine for the Management of Health and Disease. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003277101-5.

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Ganai, Shabir Ahmad. "Overview of Epigenetic Signatures and Their Regulation by Epigenetic Modification Enzymes." In Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8179-3_1.

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Ganai, Shabir Ahmad. "Combining Histone Deacetylase Inhibitors with Other Anticancer Agents as a Novel Strategy for Circumventing Limited Therapeutic Efficacy and Mitigating Toxicity." In Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8179-3_10.

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Ganai, Shabir Ahmad. "Futuristic Approaches Towards Designing of Isozyme-Selective Histone Deacetylase Inhibitors Against Zinc-Dependent Histone Deacetylases." In Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8179-3_11.

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Ganai, Shabir Ahmad. "Epigenetic Regulator Enzymes and Their Implications in Distinct Malignancies." In Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8179-3_2.

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Konferenzberichte zum Thema "COMBINATORIAL THERAPY"

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Xavierselvan, Marvin, Ronak Shethia, Brooke Bednarke, Satya Siva Kishan Yalamarty, and Srivalleesha Mallidi. "Enhancing efficacy in hypoxic HNC spheroids with PDT-based combinatorial treatments." In Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXIII, edited by David H. Kessel, Tayyaba Hasan, and Edward V. Maytin. SPIE, 2025. https://doi.org/10.1117/12.3043981.

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Khatun, Sajmina, Monika Pebam, Anamika Verma, and Aravind Kumar Rengan. "Harnessing Nature's Fury: Hyptis Suaveolens-IR775 Encapsulated Biodegradable Liposome for Combinatorial Photothermal Therapy of Lung Cancer." In 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2024. http://dx.doi.org/10.1109/nems60219.2024.10639872.

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Amiji, Mansoor M. "Multifunctional combinatorial-designed nanoparticles for nucleic acid therapy." In SPIE Defense + Security, edited by Thomas George, Achyut K. Dutta, and M. Saif Islam. SPIE, 2016. http://dx.doi.org/10.1117/12.2224764.

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Lam, Kit S., and Ruiwu Liu. "From Combinatorial Chemistry to Nanotechnology to Cancer Therapy." In The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.014.

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Wang, Yangyang, Shalin S. Patel, Juan Cong, et al. "Abstract 3639: Combinatorial therapy for triple negative breast cancer." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3639.

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Nguyen, J. P., M. Bianca, R. D. Huff, et al. "Development of a Novel Combinatorial Therapy for Cystic Fibrosis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2580.

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Lam, Kit S. "From Combinatorial Chemistry to Nanocarriers for Cancer Therapy and Imaging." In Asia Communications and Photonics Conference. OSA, 2012. http://dx.doi.org/10.1364/acp.2012.as3e.4.

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Lam, Kit S. "From Combinatorial Chemistry to Nanocarriers for Cancer Therapy and Imaging." In Asia Communications and Photonics Conference. OSA, 2012. http://dx.doi.org/10.1364/acpc.2012.as3e.4.

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Srivastava, Jyoti, Devaraja Rajasekaran, Ayesha Siddiq, et al. "Abstract 5400: A novel combinatorial therapy for hepatocellular carcinoma (HCC)." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5400.

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Bölükbas, Deniz Ali, Stefan Datz, Charlotte Meyer-Schwickerath, et al. "Combinatorial delivery of targeted mesoporous silica nanoparticles for lung cancer therapy." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2841.

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Berichte der Organisationen zum Thema "COMBINATORIAL THERAPY"

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Baia, Gilson S. Combinatorial Therapy Approaches for NF2-Deficient Meningiomas. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada567130.

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Baia, Gilson S. Combinatorial Therapy Approaches for NF2-Deficient Meningiomas. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada584501.

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