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1

Maryin, G. G., A. V. Tutelyan, O. A. Gruzdeva, et al. "Role of natural and synthetic immunotropic agents in the prevention of acute respiratory infections." Infekcionnye bolezni 18, no. 3 (2020): 131–38. http://dx.doi.org/10.20953/1729-9225-2020-3-131-138.

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Respiratory tract infections (influenza, acute respiratory infections (ARIs), community-acquired pneumonia, etc.) pose a serious threat to organized groups (including military personnel, cadets, students of military universities, and schools). The most common complication of ARI is community-acquired pneumonia, severe forms of which may result in an unfavorable outcome. The use of some drugs, such as Carmolis ensures a 2.0–3.8 times reduction in the incidence of ARIs in organized groups and a 2.3–3.0 times reduction in the incidence of community-acquired pneumonia. Carmolis has a pronounced no
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Khan, Samrah Tahir, Hira Idrees, Maryam Aftab, Asmara Imtiaz, and Muhammad Amjad Khan. "Antibiotic Resistance in Laboratory acquired infections-A Review." Lahore Garrison University Journal of Life Sciences 3, no. 3 (2020): 147–62. http://dx.doi.org/10.54692/lgujls.2019.030371.

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Laboratory acquired infection occur globally. These infections are caused by multiple parasites and pathogens belonging to bacteria, fungi and the viruses. Laboratory acquired infections in laboratories of research and development; production installations and academic sectors i.e., teaching labs vary, but do contribute to morbidity and mortality with respect to their occurrence. The health status of a lab worker or technician is an important factor in keeping the community health as these acquired infections easily get introduced into the community. The current review gives an overview about
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S, Yi. "A Case Report on Community Acquired Postpartum Group A Streptococcus Septicemia." Open Access Journal of Gynecology 8, no. 1 (2023): 1–5. http://dx.doi.org/10.23880/oajg-16000254.

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Group A streptococcus is commonly found in the skin or mucosa of vagina or throat. It can be responsible for a wide variety of infections that can range from mild to life threatening and lethal. Common infections caused by this bacterium include pharyngitis, impetigo, and scarlet fever. More serious complications include rheumatic fever, post streptococcal glomerulonephritis, streptococcal toxic shock syndrome, amputation, necrotizing fasciitis, pneumonia, bacteremia, and multiorgan failure. This case report presents the management of a case of suspected community acquired group a streptococcu
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Shbaklo, Nour, Francesco Tandoi, Tommaso Lupia, Silvia Corcione, Renato Romagnoli, and Francesco Giuseppe De Rosa. "Bacterial and Viral Infections in Liver Transplantation: New Insights from Clinical and Surgical Perspectives." Biomedicines 10, no. 7 (2022): 1561. http://dx.doi.org/10.3390/biomedicines10071561.

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End-stage liver disease patients undergoing liver transplantation are prone to develop numerous infectious complications because of immunosuppression, surgical interventions, and malnutrition. Infections in transplant recipients account for the main cause of mortality and morbidity with rates of up to 80%. The challenges faced in the early post-transplant period tend to be linked to transplant procedures and nosocomial infections commonly in bloodstream, surgical, and intra-abdominal sites. Viral infections represent an additional complication of immunosuppression; they can be donor-derived, r
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Rosso, Giuseppina, and Maurizio Salvadori. "Infective complications in the renal transplant recipients." Giornale di Clinica Nefrologica e Dialisi 36, no. 1 (2024): 1–6. http://dx.doi.org/10.33393/gcnd.2024.3017.

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Infections remain a common complication of solid-organ transplantation and are a major factor of morbidity and mortality in renal transplant recipients. The incidence of infection in renal transplant patients is directly related to the net immunosuppressive effect achieved and the duration of the administration of immunosuppressive therapy. The major types of infections can be categorized according to the time post-transplant during which they occur: in the first month after transplantation post-surgical bacterial infections and in the period from one to four months post-transplant opportunist
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Al-Obaidi, Mohanad, and Tirdad T. Zangeneh. "705. Community Acquired Gastrointestinal Infections among Transplant Recipients." Open Forum Infectious Diseases 8, Supplement_1 (2021): S453. http://dx.doi.org/10.1093/ofid/ofab466.902.

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Abstract Background Community-acquired gastrointestinal (cGI) infections carry a significant risk of mortality and morbidity. Transplant patients are at increased risk of infectious complications. We aimed to study the risks and outcomes of cGI infections in this population. Methods After the institutional review board’s approval, a multi-center retrospective study was conducted. Data was collected from inpatient admission for patients with a history of hematopoietic stem transplantation or solid organ transplantation. Data regarding patient demographics, gastrointestinal polymerase chain reac
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Zhang, Qun, Pan Wang, Menghuan Shen, and Chun Shan. "Clinical characteristics and risk factors for Klebsiella pneumoniae bloodstream infection in 152 immunocompetent patients." Journal of Infection in Developing Countries 18, no. 02 (2024): 219–26. http://dx.doi.org/10.3855/jidc.18204.

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Objective: To investigate the clinical characteristics and prognostic risk factors for Klebsiella pneumoniae bloodstream infections in immunocompetent patients. Methods: The study included patients with K. pneumoniae bloodstream infection treated in Zhongda Hospital from June 2016 to June 2021. Clinical data and antibiotic susceptibility test results were retrospectively collected and analyzed. Independent risk factors for mortality were screened using the chi-square test and multivariate logistic regression. Results: A total of 152 patients were included in the analysis. In our cohort, 77.6%
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Shah, Rabeea, Naseem Salahuddin, Shameem Behram Khan, Rabiah Masroor, and Kiran Abbas. "Characteristics and Outcomes of Community Acquired Versus Hospital Acquired Sepsis at A Tertiary Care Hospital, Karachi." Pakistan Journal of Medical and Health Sciences 16, no. 11 (2022): 741–44. http://dx.doi.org/10.53350/pjmhs20221611741.

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Objective: The study compared the demographics, clinical characteristics and site of infection leading to community acquired and hospital acquired sepsis. Secondly, the study further compared the distribution of the isolated organisms and complications caused by community and hospital acquired sepsis. Methods: A prospective cohort study was undertaken at the intensive care unit, high dependency unit, and critical care unit at the Indus Hospital, Karachi, Pakistan between 14-April-2021 to 15th-April-2022. All the individuals diagnosed with sepsis, admitted through the Emergency Department or tr
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Zaytseva, A. A., E. B. Bukreeva, T. S. Ageeva, et al. "Features of the clinical presentation and course of community-acquired pneumonia against the background of type 2 diabetes mellitus." Bulletin of Siberian Medicine 21, no. 2 (2022): 145–51. http://dx.doi.org/10.20538/1682-0363-2022-2-145-151.

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Community-acquired pneumonia remains the leading infectious cause of death around the world. Many factors influence the prognosis and outcome of this disease. Compared with healthy individuals, patients with diabetes mellitus are at increased risk of respiratory tract infections, such as community-acquired pneumonia. Diabetes mellitus contributes to the development of pulmonary thrombotic microangiopathy, changing the functional state of the lungs. In numerous studies involving patients with diabetes mellitus, data on the state of the lungs were obtained by instrumental tests, such as spiromet
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Lamb, Avinash, and Amol Harinathrao Patil. "Management and outcome of community acquired pneumonia: hospital based study." International Journal of Research in Medical Sciences 6, no. 7 (2018): 2271. http://dx.doi.org/10.18203/2320-6012.ijrms20182404.

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Background: Lower Respiratory Tract infections are responsible for one-fifth of the deaths caused due to infectious diseases in India and Pneumonia is a major culprit. Timely and appropriate empirical treatment based on knowledge of local etiological factors is important in the management of the disease. Data related to investigation profile and therapy as well as morbidity and mortality is available from different geographic regions. Present study describes the management and outcome of disease data from a tertiary hospital at Rajkot in Gujarat state during the study period.Methods: The prese
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Dhedeepyaa, Dr Kothapally Sai, Dr K. Ramesh Kumar, Dr Ranganath D, Dr Mohd Ansar Hussain, and Dr G. Shreya Reddy. "To Determine the Predisposing Factors, Clinical Features, Bacteriological, Radiological Features of Community Acquired Pneumonia and its Complications." Scholars Journal of Applied Medical Sciences 9, no. 11 (2021): 1657–64. http://dx.doi.org/10.36347/sjams.2021.v09i11.003.

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Community acquired pneumonia is one the most common acute infections requiring admission in hospital. It is major cause of mortality and morbidity. Incidence of community acquired pneumonia is increased with age, Smoking and Diabetes. Communtiy acquired Pneumonia with Parapneumonic effusion is common feature. High index of suspicion, good clinical examination and necessity intervention in ICU are life saving with low mortality. We made an attempt to understand the mode of presentation, its clinical features, bacteriological and radiological features for the early detection of disease and empha
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Sergeeva, Evgeniya V., and Svetlana I. Petrova. "Community-acquired pneumonia in children. The modern features." Pediatrician (St. Petersburg) 7, no. 3 (2016): 5–10. http://dx.doi.org/10.17816/ped735-10.

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Acute respiratory infections are one of the most frequent diseases among children and teenagers around the World. Pneumonia which caused by infectious agents is dangerous disease of the lower respiratory tract that can lead to the death. The continuing high level of morbidity and mortality causes the issue. The article describes the WHO criteria for the diagnosis of community-acquired pneumonia (CAP) and CAP severity indicators, also radiographic signs of CAP and modern epidemiological data. The etiological structure of CAP has age-specific peculiarities. Streptococcus pneumoniae (S. pneumonia
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Mitra, Mario, Andrea Mancuso, Flavia Politi, and Alberto Maringhini. "Bacterial infections in cirrhosis: a narrative review and key points for clinical practice." Italian Journal of Medicine 14, no. 3 (2020): 126–35. http://dx.doi.org/10.4081/itjm.2020.1306.

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Bacterial infections are frequent complications of liver cirrhosis, accounting for severe clinical courses, and increased mortality. The reduction of the negative clinical impact of infections may be achieved by a combination of prophylactic measures to reduce the occurrence, early identification, and management. Spontaneous bacterial peritonitis (SBP), urinary tract infections, pneumonia, cellulitis, and spontaneous bacteremia are frequent in cirrhosis. The choice of initial empirical antimicrobial therapy should be based on both site, severity, and origin of infection (community-acquired, no
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Dr.Hadia, Riaz Dr.Mehwish Kalsoom Dr.Saba Irshad. "MANAGEMENT AND OUTCOME OF COMMUNITY ACQUIRED PNEUMONIA IN A TERTIARY CARE HOSPITAL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 02 (2019): 4706–10. https://doi.org/10.5281/zenodo.2582304.

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<strong><em>Background: </em></strong><em>Lower Respiratory Tract (LRT) infections are the reason of 1/5 the deaths caused due to infectious diseases and Pneumonia. Timely and appropriate empirical treatment based on knowledge of local etiological factors is important in the management of the disease. Investigation data has been available from different geographical regions. </em> <strong><em>Methods: </em></strong><em>The present prospective observational study was completed in the study duration at CHEST Medicine Ward of Services Hospital lahore. The number of patients included in the study
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Ozbay, Sedat, Mustafa Ayan, Orhan Ozsoy, Canan Akman, and Ozgur Karcioglu. "Diagnostic and Prognostic Roles of Procalcitonin and Other Tools in Community-Acquired Pneumonia: A Narrative Review." Diagnostics 13, no. 11 (2023): 1869. http://dx.doi.org/10.3390/diagnostics13111869.

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Community-acquired pneumonia (CAP) is among the most common causes of death and one of the leading healthcare concerns worldwide. It can evolve into sepsis and septic shock, which have a high mortality rate, especially in critical patients and comorbidities. The definitions of sepsis were revised in the last decade as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. Procalcitonin (PCT), C-reactive protein (CRP), and complete blood count, including white blood cells, are among the most commonly analyzed sepsis-specific biomarkers also used in pneumonia i
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Önal, Pınar, Gözde Apaydın Sever, Beste Akdeniz Eren, et al. "Investigating Different Clinical Manifestations of Staphylococcus aureus Infections in Childhood—Can D-Dimer and Fibrinogen Predict Deep Tissue Invasion?" Children 12, no. 8 (2025): 959. https://doi.org/10.3390/children12080959.

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Background: Staphylococcus aureus is a significant pathogen causing both local and systemic infections in children, with deep tissue involvement leading to severe complications. This study aimed to assess clinical manifestations and identify risk factors for deep tissue involvement in pediatric S. aureus infections. Methods: All children between 1 month and 18 years who had S. aureus growth in blood, pus, or joint fluid culture were included. Results: A total of 61 patients (median age 55 months) were included, with 22.9% having deep tissue infections. Osteoarticular infections, pyomyositis, a
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Argunova, A. N., Zh V. Bondareva, E. S. Prokopiev, and O. М. Nosikhina. "Analysis of Morbidity Dynamics and Factors Influencing the Development of Pneumococcal Infections among the Adult Population of the Sakha Republic (Yakutia)." Epidemiology and Vaccine Prevention 17, no. 4 (2018): 38–45. http://dx.doi.org/10.31631/2073-3046-2018-17-4-38-45.

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The pneumococcal infection is an important issue due to its prevalence, numerous severe complications, high mortality rate and disability. However modern vaccination allows preventing of the pneumococcal infection and reduces the severity of clinical complications. This article presents the analysis of the morbidity and mortality indicators from community-acquired pneumonia and the effect of pneumococcal vaccination on its dynamic in the at-risk groups within the adult population of the Aldan area and the city of Aldan of the Sakha Republic (Yakutia). In the Aldan area pneumonia morbidity pers
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Houlihan, Elaine, Raymond McLoughlin, and Ruth Waldron. "Streptococcus pneumoniae purulent pericarditis secondary to influenza A infection and pneumococcal pneumonia in an immunocompetent woman." BMJ Case Reports 14, no. 3 (2021): e240763. http://dx.doi.org/10.1136/bcr-2020-240763.

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A 44-year-old previously well woman presented with features of respiratory sepsis including a productive cough and fevers, with a recent preceding influenza-like illness. She was diagnosed with community-acquired pneumonia on chest radiograph, influenza infection via nasopharyngeal swab and Streptococcus pneumoniae bloodstream infection with associated purulent pericarditis. She was managed with pericardial drainage and concurrent treatment with antibiotics and made an excellent recovery. This case highlights the complications of both influenza and S. pneumoniae infections, and the importance
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Korkmazov, M. Yu, N. V. Kornova, M. A. Lengina, A. A. Smirnov, A. M. Korkmazov, and I. D. Dubinets. "Effective antibiotic therapy for community-acquired otorhinolaryngological respiratory infection (clinical description)." Meditsinskiy sovet = Medical Council, no. 20 (November 16, 2022): 73–81. http://dx.doi.org/10.21518/2079-701x-2022-16-20-73-81.

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The State Report on the state of sanitary and epidemiological well-being of the population in the Russian Federation speaks of the continued growth of respiratory infections, reaching more than 33 million cases and amounting to more than 606 billion rubles of direct economic damage in 2021. Of particular importance is the new coronavirus infection SARS-CoV-2, and manifestations of its various new genovariants, for example, variant B.1.1.529 called omicron, causes various inflammatory nosologies on the part of the mucous membranes of the ENT organs (acute rhinosinusitis, acute tonsillopharyngit
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Piljić, Dilista, Dragan Piljić, Sead Ahmetagić, Farid Ljuca, and Humera Porobić-Jahić. "Clinical and Laboratory Characteristics of Acute Community-Acquired Urinary Tract Infections in Adult Hospitalised Patients." Bosnian Journal of Basic Medical Sciences 10, no. 1 (2010): 49–53. http://dx.doi.org/10.17305/bjbms.2010.2735.

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Urinary tract infections (UTI) cause a great number of morbidity and mortality. These infections are serious complications in pregnancy, patients with diabetes, polycystic kidneys disease, sickle cell anaemia, kidney transplant and in patients with functional or structural anomalies of the urinary tract. The aim of this investigation was to determine a dominant causative agents of UTI and some of the clinical and laboratory characteristics of acute community-acquired UTI in adult hospitalised patients. We studied 200 adult patients with acute community-acquired UTI hospitalised in the Clinic f
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Gruszecka, Jolanta, and Rafał Filip. "Epidemiological Study of Pathogens in Spontaneous Bacterial Peritonitis in 2017–2024—A Preliminary Report of the University Hospital in South-Eastern Poland." Microorganisms 12, no. 5 (2024): 1008. http://dx.doi.org/10.3390/microorganisms12051008.

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Spontaneous Bacterial Peritonitis (SBP) is a serious complication and a common cause of death in patients with liver cirrhosis. Between January 2017 and March 2024, a retrospective study was conducted involving 302 patients (&gt;18 years old) with ascites treated at a tertiary referral center in south-eastern Poland. Microbiological analysis of the ascitic fluids was performed in all patients. The presence of microorganisms was found in samples from 17 patients, and 21 pathogens were isolated, including 15 Gram-positive bacteria and 6 Gram-negative bacteria. Staphylococcus epidermidis, MRCNS (
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Worden, Lacy, Lisa E. Dumkow, Lisa E. Dumkow, Kali VanLangan, Thomas Beuschel, and Andrew Jameson. "695. Antipseudomonal Versus Narrow-spectrum Agents for the Treatment of Community-onset Intra-abdominal Infections." Open Forum Infectious Diseases 8, Supplement_1 (2021): S449. http://dx.doi.org/10.1093/ofid/ofab466.892.

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Abstract Background Antipseudomonal antibiotic regiments are often used to treat community-acquired intra-abdominal infections (CA-IAI) despite common causative pathogens being susceptible to more narrow-spectrum agents. The purpose of this study was to compare post-infection complications in adult patients treated for CA-IAI with antipseudomonal or narrow-spectrum regimens Methods This retrospective cohort study included patients ≥18 years admitted for CA-IAI treated with antibiotics between January 1, 2013, and December 31, 2019. Patients who had bacteremia or peritonitis were excluded. The
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Solanga Arachchige, Anushika Luckmy, and Dushantha Madegedara. "CHARACTERISTICS OF COMMUNITY ACQUIRED PNEUMONIA AT A SINGLE CENTER IN CENTRAL SRI LANKA DURING COVID-19 PANDEMIC: A DESCRIPTIVE CROSS-SECTIONAL STUDY." International Journal of Research -GRANTHAALAYAH 11, no. 5 (2023): 97–111. http://dx.doi.org/10.29121/granthaalayah.v11.i5.2023.5180.

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Introduction and Objective:Community acquired pneumonia (CAP) is associated with increased mortality and morbidity. The disease severity is multifactorial, co-morbid conditions and advanced age are the most important risk factors. At present, there is a sparsity in published data on CAP in Sri Lankan adults and adolescents. Aim of study to identify complications and outcome of CAP.Methods:A single center descriptive prospective study was carried out in Respiratory Unit 11 in National Hospital-Kandy, Sri Lanka, among diagnosed CAP patients during six months from 1st of September 2020 to 28th of
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Khusnutdinova, Tatiana A., Elena V. Shipitsyna, Anna A. Krysanova, Alevtina M. Savicheva, and Roman V. Kapustin. "Antibiotic resistance of pathogens causing community-acquired urinary tract infections in pregnant women with diabetes mellitus." Journal of obstetrics and women's diseases 72, no. 1 (2023): 53–62. http://dx.doi.org/10.17816/jowd115215.

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BACKGROUND: Urinary tract infections are among the most common infectious diseases in women and are the most frequent cause of infectious complications of pregnancy, especially in pregnant women with type 1 diabetes mellitus. For adequate treatment of urinary tract infections in pregnant women with type 1 diabetes mellitus, it is requisite to regularly monitor antimicrobial resistance of uropathogens in order to update empirical schemes of antibacterial therapy.&#x0D; AIM: The aim of this study was to determine the spectrum of uropathogens and the activity of antibacterial drugs against pathog
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Kraeva, L. A., O. A. Burgasova, I. S. Petrova, et al. "Antibiotic resistance of Moraxella catarrhalis strains isolated from patients with complicated acute respiratory viral infections and other acute respiratory diseases." Infekcionnye bolezni 19, no. 3 (2021): 85–91. http://dx.doi.org/10.20953/1729-9225-2021-3-85-91.

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In recent years, acute respiratory viral infections (ARVIs) and other acute respiratory diseases (ARDs) have acquired some new characteristics of the disease course. The structure of complications has changed, in particular, such complications as community-acquired pneumonia (CAP) and lesions to the upper respiratory tract have become significantly more common. CAP remains one of the main causes of death in patients with ARVIs and other acute respiratory infections due to bacterial resistance to antibiotics. Objective. To assess drug sensitivity of Moraxella catarrhalis strains isolated from p
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Maloletnikova, I. M., and N. S. Paramonova. "ETIOLOGICAL STRUCTURE OF ACUTE COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN." Journal of the Grodno State Medical University 22, no. 1 (2024): 73–77. http://dx.doi.org/10.25298/2221-8785-2024-22-1-73-77.

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Background. Difficulties in the etiological diagnosis of pneumonia in children are due to its polyetiology. Pneumonia can be caused by both typical bacterial agents and atypical pathogens. The condition of frequently ill children is characterized by a combination of several pathogens, in particular, a viral-bacterial association. The frequent use of antibacterial therapy in a group of frequently ill children should be taken into account when choosing initial therapy in a hospital. Objective. To establish the etiological structure of acute community-acquired pneumonia in frequently ill children
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Zhang, Jin. "Review on the laboratory diagnosis of Mycoplasma pneumoniae infection." Infection International 7, no. 3 (2018): 67–74. http://dx.doi.org/10.2478/ii-2018-0030.

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AbstractMycoplasma pneumoniae(MP) is an important pathogen of community-acquired pneumonia in children. As a type of self-limited disease, most MP infections cause mild clinical symptoms, but they can also lead to severe pneumonia or extrapulmonary complications. The resistance rate of MP has increased in recent years. Early and rapid diagnosis of MP infection is important for the treatment and prognosis of the disease. Current methods for diagnosing MP infection include isolation culture, serological diagnosis, and molecular biological diagnosis. This review summarizes the recent research pro
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Elabd, Hatem, Anjuli Eagleston, Dominique Brandt, and Stephen Blatt. "267. Characteristics and Trends of Serratia Blood Stream Infections." Open Forum Infectious Diseases 7, Supplement_1 (2020): S133—S134. http://dx.doi.org/10.1093/ofid/ofaa439.311.

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Abstract Background Serratia is an opportunistic pathogen known to cause an array of infectious presentations including UTIs, pneumonia, wound infections, skin and soft tissue infections, surgical site infections and although rare, endocarditis and bacteremia. The aim of the proposed study is to identify the characteristics of patients with community-acquired Serratia blood stream infection over a five-year period within the TriHealth inpatient population within the Cincinnati, Ohio Region. The study will also examine antibiotic resistance patterns among patients with Serratia bloodstream infe
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Maraolo, Alberto Enrico, Antonio Riccardo Buonomo, Emanuela Zappulo, Riccardo Scotto, Biagio Pinchera, and Ivan Gentile. "Unsolved Issues in the Treatment of Spontaneous Peritonitis in Patients with Cirrhosis: Nosocomial Versus Community-acquired Infections and the Role of Fungi." Reviews on Recent Clinical Trials 14, no. 2 (2019): 129–35. http://dx.doi.org/10.2174/1574887114666181204102516.

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Introduction:Historically, spontaneous bacterial peritonitis (SBP) has represented one of the most frequent and relevant infectious complications of advanced liver disease, and this is still valid today. Nevertheless, in recent years the role of fungi as causative pathogens of primary peritonitis in patients with cirrhosis has become not negligible. Another issue is linked with the traditional distinction, instrumental in therapeutic choice, between community-acquired and nosocomial forms, according to the onset. Between these two categories, another one has been introduced: the so-called “hea
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Aybazova, M. I., N. V. Dryagina, L. M. Tsentsiper, L. A. Shmidt, N. V. Goncharuk, and A. N. Kondratyev. "Nosocomial meningitis and ventriculitis: clinic, diagnosis, prevention (literature review)." Messenger of ANESTHESIOLOGY AND RESUSCITATION 22, no. 3 (2025): 108–18. https://doi.org/10.24884/2078-5658-2025-22-3-108-118.

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The objective was to summarize data from the literature on methods of diagnosis and prevention of nosocomial meningitis.Nosocomial meningitis (NM) and ventriculitis are severe, often life-threatening complications in neurosurgery. Currently, postoperative meningitis, shunt infections, and drainage-associated ventriculitis are distinguished. For each of the above groups of diseases, there are specific diagnostic approaches, etiotropic agents, and treatments that differ significantly from community-acquired infections of the central nervous system. Pathogens are represented by a wide range of op
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Patel, Dikesh Kumar Thakorbhai, Kumar Panjibhai Ganvit Manoj, and Kumar Rajendrabhai Chaudhary Minesh. "Study of Clinical Profile of Respiratory Diseases in Geriatric Population." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 1766–68. https://doi.org/10.5281/zenodo.11140943.

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Geriatric individuals are more susceptible to different infections, especially respiratory-tract infections (RTIs) due to their compromised immune system. Hence, the objectives was to study the profile of respiratory diseases in geriatric population attending a tertiary care centre. Geriatric patients, those consenting, with respiratory complaints attending Department of Respiratory Medicine, were taken up for study. 200 patients were included in study, 120 males and 80 females. 30% patients were of Upper Respiratory Tract Infection, 24% cases were of Chronic Obstructive Pulmonary Disease, 10%
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Patel, Dikesh Kumar Thakorbhai, Kumar Panjibhai Ganvit Manoj, and Kumar Rajendrabhai Chaudhary Minesh. "Study of Clinical Profile of Respiratory Diseases in Geriatric Population." International Journal of Pharmaceutical and Clinical Research 15, no. 10 (2024): 1575–77. https://doi.org/10.5281/zenodo.11312183.

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Geriatric individuals are more susceptible to different infections, especially respiratory-tract infections (RTIs) due to their compromised immune system. Hence, the objectives was to study the profile of respiratory diseases in geriatric population attending a tertiary care centre. Geriatric patients, those consenting, with respiratory complaints attending Department of Respiratory Medicine, were taken up for study. 200 patients were included in study, 120 males and 80 females. 30% patients were of Upper Respiratory Tract Infection, 24% cases were of Chronic Obstructive Pulmonary Disease, 10
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Rius-Peris, J. M., P. Tambe, M. Chilet Chilet Sáez, M. Requena, E. Prada, and J. Mateo. "Incidence and Severity of Community- and Hospital-Acquired Hyponatremia in Pediatrics." Journal of Clinical Medicine 11, no. 24 (2022): 7522. http://dx.doi.org/10.3390/jcm11247522.

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Hyponatremia is the most common electrolyte disturbance in hospitalized children, with a reported incidence of 15–30%, but its overall incidence and severity are not well known. The objective of our study was to determine the incidence, severity, and associated risk factors of community- and hospital-acquired hyponatremia on a general pediatric ward. Data of 5550 children admitted from June 2012 to December 2019 on plasma sodium and discharge diagnosis were analyzed by logistic regression model. Clinically relevant diagnostic groups were created. Hyponatremia was classified as mild, moderate,
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Maukayeva, S. B., G. I. Nuralinova, Zh B. Issabekova, et al. "COMMUNITY-ACQUIRED PNEUMONIA IN PREGNANT. CLINICAL CASE." Наука и здравоохранение, no. 6(26) (December 30, 2024): 234–41. https://doi.org/10.34689/sh.2024.26.6.027.

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Introduction.Community-acquired pneumonia is the leading cause of morbidity and mortality worldwide. The clinical features, diagnosis, and treatment of respiratory infections in pregnant and nonpregnant patients are generally similar, although there are risk factors. The incidence rates of community-acquired pneumonia in pregnant women range from 0.2 to 8.5 per 1,000 births. Concomitant diseases such as asthma, smoking, malnutrition, liver disease, chronic obstructive pulmonary disease, and pregnancy increase the risk of complications. A wide range of microorganisms can cause pneumonia during
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Zaitsev, A. A. "Epidemiology and pharmacotherapy of lower respiratory tract infections: role of inhibitor-protected aminopenicillins." Medical Council, no. 15 (October 12, 2018): 76–81. http://dx.doi.org/10.21518/2079-701x-2018-15-76-81.

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The article is devoted to the role of inhibitor-protected aminopenicillins in the treatment of community-acquired infections of the lower respiratory tract. Data are provided on the relevance of LRTIs, the aetiology of CAP and infectious exacerbations of COPD, the pharmacological characteristics of amoxicillin /clavulanate, which allowed it to occupy a leading role in the antibiotic therapy regimens of these diseases. The paper presented modern ideas about the directions of antimicrobial therapy of CAP and its complications (lung abscess, pleural empyema). It considered the antibacterial thera
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Shimizu, Akihiro, Tetsuya Horino, Yumiko Hosaka, et al. "1069. Predictive Factors for Metastatic Infection in Patients With Bacteremia Caused by Staphylococcus aureus." Open Forum Infectious Diseases 5, suppl_1 (2018): S320. http://dx.doi.org/10.1093/ofid/ofy210.906.

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Abstract Background Metastatic infections, such as infective endocarditis and pyogenic spondylitis, are very serious complications of Staphylococcus aureus bacteremia (SAB), because failure to identify metastatic infections may cause poor prognosis. The aim of the present study is to determine the predictive factors for metastatic infections of SAB. Methods This retrospective cohort study was conducted among patients with bacteremia due to S. aureus (including both methicillin-sensitive S. aureus and methicillin-resistant S. aureus: MSSA and MRSA) in The Jikei University Kashiwa Hospital. The
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Laratta, Matteo, Stefano Agliardi, Matteo Sola, Stefano Spina, and Roberto Fumagalli. "Effective Management of a Skin and Soft Tissue Infection Caused by Community-Acquired MRSA Through Triple-Targeted Therapy Along with Aggressive Source Control: A Case Report." Infectious Disease Reports 17, no. 2 (2025): 27. https://doi.org/10.3390/idr17020027.

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Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of healthcare-associated infections in Europe. It has become increasingly prevalent in community settings, causing skin and soft tissue infections (SSTIs). Managing community-acquired (CA) MRSA infections is challenging due to its high virulence and resistance to common antibiotics, and prevention outside the hospital setting is complex. Combination therapy has demonstrated efficacy in the treatment of severe MRSA infections. Furthermore, surgical source control is critical in treating CA-MRSA infections, inv
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Wald, Ellen R., Nancy Guerra, and Carol Byers. "Upper Respiratory Tract Infections in Young Children: Duration of and Frequency of Complications." Pediatrics 87, no. 2 (1991): 129–33. http://dx.doi.org/10.1542/peds.87.2.129.

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This study was performed to determine the usual duration of community-acquired viral upper respiratory tract infections and the incidence of complications (otitis media/sinusitis) of these respiratory tract infections in infancy and early childhood. Children in various forms of child-care arrangements (home care, group care, and day care) were enrolled at birth and observed for 3 years. Families were telephoned every 2 weeks to record on a standardized form the type and severity of illnesses experienced during the previous interval. Only children remaining in their original child-care group fo
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Kalmanson, L. M., I. V. Shlyk, Yu S. Polushin, O. V. Stanevich, and A. A. Galkina. "The Effect of Nosocomial Infection on the Severity and Outcome of the Disease in Patients with Severe and Extremely Severe COVID-19." Messenger of ANESTHESIOLOGY AND RESUSCITATION 18, no. 6 (2021): 15–21. http://dx.doi.org/10.21292/2078-5658-2021-18-6-15-21.

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The mechanisms of development of nosocomial infectious complications in COVID-19 and the contribution of bacterial and mycotic superinfection to the formation of extremely high mortality among patients with severe and extremely severe course of this disease have not yet been fully revealed. The objective: to study epidemiology, risk factors for the development of nosocomial superinfection, and its effect on the severity and outcome of the disease in patients with COVID-19.Subjects and Methods. 383 cases of severe and extremely severe COVID-19 were retrospectively analyzed. Demographic data, th
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Martin, Eric, Wesam Frandah, Rishi Raj, and Kenneth Nugent. "A young adult with a fulminant <i>Staphylococcus aureus</i> infection and multiple thrombi." Chest Disease Reports 4, no. 1 (2011): e16. http://dx.doi.org/10.4081/cdr.4.204.

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Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) can induce infections of the skin and soft tissues, as well as pneumonia with necrosis. Following a minor injury, a patient developed ankle cellulitis, MRSA bacteremia, necrotizing pneumonia, respiratory failure, shock, and multiple thrombi. This case illustrates the fulminant course, the potential need for empiric antibiotic coverage upon admission for MRSA, and the high probability of thrombotic complications in these patients.
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He, Hangyong, and Richard G. Wunderink. "Staphylococcus aureus Pneumonia in the Community." Seminars in Respiratory and Critical Care Medicine 41, no. 04 (2020): 470–79. http://dx.doi.org/10.1055/s-0040-1709992.

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Abstract Staphylococcus aureus is an emergent etiology of community-acquired pneumonia (CAP) over the past 2 decades, with severe community-acquired pneumonia (SCAP) caused by methicillin-resistant S. aureus (MRSA) leading to critical illness and death. S. aureus colonization is associated with a high incidence of pneumonia. Panton-Valentine leukocidin (PVL) is one of the most important virulence factors of S. aureus associated with serious complications. In recent years, community-associated MRSA (CA-MRSA) clones that caused infections in young adults and healthy individuals with no exposure
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Nazarchuk, O. A., V. L. Vitkovskiy, and Yu M. Babina. "Use of Linezolid in the treatment of surgical infectious complications under antibiotic resistance." Perioperaciina Medicina 3, no. 2 (2021): 34–39. http://dx.doi.org/10.31636/prmd.v3i2.5.

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Linezolid – a first representative of the new class of synthetic antibiotics oxazolidones. Its antibacterial spectrum includes Gram-positive microorganisms, including multi-resistant strains. Its unique mechanism of action conditions absence of cross-resistance with other antibiotics. This drug is presented in peroral and parenteral forms. Unlike vancomycin, it has optimal pharmacokinetic profile. Linezolid was approved by Food and Drug Administration (FDA) in 2000 for the treatment of the following diseases: hospital- and community-acquired pneumonia, skin and soft tissue infections with or w
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Adenipekun, Eyitayo O., Charlene R. Jackson, Hazem Ramadan, et al. "Prevalence and multidrug resistance of Escherichia coli from community-acquired infections in Lagos, Nigeria." Journal of Infection in Developing Countries 10, no. 09 (2016): 920–31. http://dx.doi.org/10.3855/jidc.7997.

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Introduction: The emergence of multidrug resistance (MDR; resistance to ≥ 2 more antimicrobials) in Escherichia coli is of concern due to complications encountered in treatment. Methodology: In this study, prevalence, antimicrobial resistance, and genetic characteristics of MDR community isolates of E. coli from Lagos, Nigeria were determined. Urine and stool samples were obtained from outpatients attending Lagos State hospitals and from animal handlers in abattoirs, poultries, and open markets, from December 2012 to July 2013. Results: Approximately 50% of urine (200/394) and 88% of stool sam
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Bhumi, Suthar, Vachharajani Vishwa, Khanna Pragya, and Bhojak Ratna. "Serum Procalcitonin Levels in Children with Community-Acquired Pneumonia: A Cross-Sectional Study." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 315–20. https://doi.org/10.5281/zenodo.14034933.

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<strong>Background:&nbsp;</strong>Community-acquired pneumonia (CAP) continues to be a major contributor to both mortality and morbidity among children under five years of age. Recently, there has been growing interest in procalcitonin (PCT) as potential biomarker for CAP. Emerging evidence indicates that a low procalcitonin level has a high negative predictive value for ruling out typical bacterial infections in pediatric patients. In light of this, the present study aims to evaluate the clinical utility of PCT in managing pediatric CAP.&nbsp;<strong>Materials and Methods:</strong>&nbsp;This
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Loubet, Paul, Salomé Guitton, Simon Rolland, et al. "Characteristics of Human Metapneumovirus Infection Compared to Respiratory Syncytial Virus and Influenza Infections in Adults Hospitalized for Influenza-Like Illness in France, 2012–2022." Journal of Infectious Diseases 232, Supplement_1 (2025): S93—S100. https://doi.org/10.1093/infdis/jiaf082.

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Abstract Background We aimed to compare the characteristics of human metapneumovirus (hMPV) infection with influenza A and B virus (FLUV) and respiratory syncytial virus (RSV) infections in adults hospitalized with influenza-like illness (ILI). Methods We conducted a post hoc analysis of adult patients hospitalized with community-acquired ILI who were enrolled in the FLUVAC study at 5 French referral hospitals from 2012 to 2022. Results At least 1 respiratory virus was detected in 3620 of 6618 patients (55%), including FLUV (1524/3620 [42%]), RSV (248/3620 [7%]), and hMPV (162/3620 [5%]). hMPV
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Taraș, Roxana, Beatrice Mahler, Mihaela Bălgrădean, et al. "The Role of Mannose-Binding Lectin and Inflammatory Markers in Establishing the Course and Prognosis of Community-Acquired Pneumonia in Children." Children 10, no. 11 (2023): 1744. http://dx.doi.org/10.3390/children10111744.

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Background: Community-acquired pneumonia (CAP) is one of the most significant childhood diseases worldwide and a leading infectious cause of death in children. This study aimed to evaluate the prognostic value of the inflammatory markers—C-reactive protein (CRP) and procalcitonin (PCT)—and the polymorphic glycoprotein mannose-binding lectin (MBL), deficiency of which is associated with severe infections, in the determination of the optimal type and timing of therapeutic intervention for CAP in childhood. Methods: Retrospective evaluation was conducted on a cohort of 204 children aged 4 months–
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Wingard, John R., W. Garrett Nichols, and George B. McDonald. "Supportive Care." Hematology 2004, no. 1 (2004): 372–89. http://dx.doi.org/10.1182/asheducation-2004.1.372.

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Abstract To optimize treatment outcomes for hematologic malignancies, minimizing the consequences of treatment complications requires as much skill as the choice of the treatment itself. Myelosuppression and immunosuppression are frequent complications and have potentially serious infectious consequences. Invasive fungal infections and infections from respiratory viruses are increasing in frequency and have life-threatening potential. Damage to vital organs, especially the liver, is another important concern. In this chapter, the scope of invasive fungal and respiratory viral infections, recen
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Araújo Cruz, Ana Karina, Livia de Paula Caetano Mosca, Matheus Tavella da Silva, Elaine Cristina Faria, and Jorge Pamplona Pagnossa. "Epidemiological aspects and new perspectives for the prevention of diabetic foot and its consequences." International Journal of Family & Community Medicine 8, no. 6 (2024): 160–64. https://doi.org/10.15406/ijfcm.2024.08.00371.

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Diabetes Mellitus (DM) is a clinical condition characterized as a chronic non-communicable disease, which imposes challenges in the lives of individuals when neglected in the context of community and preventive health. In this context, the identification and description of the consequences acquired by this disease imply greater chances of early diagnosis of bacterial infections and mitigation of the occurrence of antibiotic resistance, developed mainly by people who have complications of DM, such as diabetic foot. This complication leads to a high number of lower limb amputations. As discussed
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Tatevosov, V. R., M. P. Kostinov, A. D. Protasov, et al. "The effectiveness of immunotherapy in the complex treatment of community-acquired pneumonia of mild course in organized groups." Astrakhan medical journal 19, no. 2 (2024): 101–10. http://dx.doi.org/10.17021/1992-6499-2024-2-101-110.

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Community-acquired pneumonia is one of the most common acute infectious diseases, especially in organized groups. Community-acquired pneumonia in military personnel is a serious problem of the medical service and is diagnosed 2–3 times more often than among civilians. The purpose of the study. To study the clinical features of the action of “Immunovac-VP-4 ®” in the complex treatment of community-acquired pneumonia in new recruits. Materials and methods. The study group included 88 conscripted military personnel from among the new recruits who were hospitalized with a diagnosis of mild communi
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Besner, Anne-Sophie, Christian Renaud, and Jocelyn Gravel. "43 Etiology of community-acquired bacterial meningitis in children seen in the emergency department in Canada." Paediatrics & Child Health 29, Supplement_1 (2024): e20-e20. http://dx.doi.org/10.1093/pch/pxae067.042.

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Abstract Background Bacterial meningitis poses a significant threat to paediatric health, resulting in substantial morbidity and mortality in children. Though previous studies have delineated the causative agents behind community-acquired meningitis, recent vaccination initiatives may have reshaped its underlying etiology. Objectives This study aimed to identify the bacteria responsible for community-acquired bacterial meningitis in children in Canada. Design/Methods This was a retrospective cohort study including children aged 1 day-18 years with confirmed bacterial meningitis, evaluated at a
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