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1

Shih, Ming-Kuei, You-Lin Tain, Chiu-Min Cheng, et al. "Separation and Identification of Resveratrol Butyrate Ester Complexes and Their Bioactivity in HepG2 Cell Models." International Journal of Molecular Sciences 22, no. 24 (2021): 13539. http://dx.doi.org/10.3390/ijms222413539.

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Resveratrol butyrate ester (RBE) complexes have demonstrated higher antioxidant capacity and anti-fat accumulation activity in previous studies. In this study, silica gel, high-performance liquid chromatography, and 1H nuclear magnetic resonance were used for separation and identification of RBE complex components. With the exception of resveratrol, five different structures of ester derivatives were separated from silica gel: 3,4′-di-O-butanoylresveratrol (ED2, 18.8%), 3-O-butanoylresveratrol (ED4, 35.7%), 4′-O-butanoylresveratrol (ED5, 4.4%), 3,5,4′-tri-O-butanoylresveratrol (ED6, 1.5%), and
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2

Adaileh, Fedaa. "Crosslinking of Water-Soluble Cyclodextrin with Hyaluronic Acid for Targeted Drug Delivery." Jordan Journal of Pharmaceutical Sciences 16, no. 2 (2023): 558. http://dx.doi.org/10.35516/jjps.v16i2.1497.

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Introduction: Most of the cytotoxic anticancer drugs belong to substances with both low solubility in aqueous fluids and poor cellular uptake, which lead to lack of specific therapy with apparent side effects. Therefore, there is a need to develop a novel drug delivery that can remotely and selectively release their payload. Curcumin(CUR) is an antibiotic, also a powerful inhibitor of the proliferation of several tumor cells.
 Aims: The aim of the present work is to highlight and discussed hyaluronic acid (HA ) to be grafted with Mono-6-deoxyl-6-ethylenediamino-γ-cyclodextrin (ɣ-CD-EDA) t
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3

Yang, Zhonglie, Yutong Liu, Kun Cao, Xiaobin Zhang, Hezhong Jiang, and Jiahong Li. "Synthetic reactions driven by electron-donor–acceptor (EDA) complexes." Beilstein Journal of Organic Chemistry 17 (April 6, 2021): 771–99. http://dx.doi.org/10.3762/bjoc.17.67.

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The reversible, weak ground-state aggregate formed by dipole–dipole interactions between an electron donor and an electron acceptor is referred to as an electron-donor–acceptor (EDA) complex. Generally, upon light irradiation, the EDA complex turns into the excited state, causing an electron transfer to give radicals and to initiate subsequent reactions. Besides light as an external energy source, reactions involving the participation of EDA complexes are mild, obviating transition metal catalysts or photosensitizers in the majority of cases and are in line with the theme of green chemistry. T
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4

Gromowski, Gregory D., Nicholas D. Barrett, and Alan D. T. Barrett. "Characterization of Dengue Virus Complex-Specific Neutralizing Epitopes on Envelope Protein Domain III of Dengue 2 Virus." Journal of Virology 82, no. 17 (2008): 8828–37. http://dx.doi.org/10.1128/jvi.00606-08.

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ABSTRACT The surface of the mature dengue virus (DENV) particle is covered with 180 envelope (E) proteins arranged as homodimers that lie relatively flat on the virion surface. Each monomer consists of three domains (ED1, ED2, and ED3), of which ED3 contains the critical neutralization determinant(s). In this study, a large panel of DENV-2 recombinant ED3 mutant proteins was used to physically and biologically map the epitopes of five DENV complex-specific monoclonal antibodies (MAbs). All five MAbs recognized a single antigenic site that includes residues K310, I312, P332, L389, and W391. The
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5

Jorge, C. Herrera-Luna, Carmen Pérez-Aguilar María, Gerken Leon, García Mancheño Olga, Consuelo Jiménez M., and Pérez-Ruiz Raúl. "Effective Formation of New C(sp2)−S Bonds via Photoactivation of Alkylamine-based Electron Donor-Acceptor Complexes." Chem. Eur. J. 29, no. 6 (2023): e202203353. https://doi.org/10.1002/chem.202203353.

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An effective approach for the direct thiolation of five-membered heteroarenes involving visible-light-absorbing EDA complexes is reported. The reaction takes place from an EDA complex between an alkylamine and the heteroarene halide. Selective photolysis to the EDA complex has allowed to generate the heteroarene radical that is suitably trapped by disulfide derivatives, providing a potent synthetic versatility.
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6

Rodriguez-Parada, Jose M., and Virgil Percec. "Interchain EDA complexes: A model for LCST?" Journal of Polymer Science Part A: Polymer Chemistry 24, no. 3 (1986): 579–87. http://dx.doi.org/10.1002/pola.1986.080240316.

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7

Lin, Li, Zhonglie Yang, Jianchen Liu, et al. "Visible-light-induced surfactant-promoted sulfonylation of alkenes and alkynes with sulfonyl chloride by the formation of an EDA-complex with NaI in water at room temperature." Green Chemistry 23, no. 15 (2021): 5467–73. http://dx.doi.org/10.1039/d1gc00956g.

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We report an efficient visible-light-induced iodosulfonyl reaction of alkenes in water using an EDA complex strategy at room temperature. The addition of a cationic surfactant allows for the easy formation of colored EDA complexes in water.
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8

Kwiecień, Anna, Jana Ruda-Kucerova, Kamil Kamiński, et al. "Improved Pharmacokinetics and Tissue Uptake of Complexed Daidzein in Rats." Pharmaceutics 12, no. 2 (2020): 162. http://dx.doi.org/10.3390/pharmaceutics12020162.

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The pharmacokinetic profile and tissue uptake of daidzein (DAI) was determined in rat serum and tissues (lungs, eyes, brain, heart, spleen, fat, liver, kidney, and testes) after intravenous and intraperitoneal administration of DAI in suspension or complexed with ethylenediamine-modified γ-cyclodextrin (GCD-EDA/DAI). The absolute and relative bioavailability of DAI suspended (20 mg/kg i.v. vs. 50 mg/kg i.p.) and complexed (0.54 mg/kg i.v. vs. 1.35 mg/kg i.p.) was determined. After i.p. administration, absorption of DAI complexed with GCD-EDA was more rapid (tmax = 15 min) than that of DAI in s
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9

Jeliński, Tomasz, Maciej Przybyłek, Magdalena Mianowana, Kinga Misiak, and Piotr Cysewski. "Deep Eutectic Solvents as Agents for Improving the Solubility of Edaravone: Experimental and Theoretical Considerations." Molecules 29, no. 6 (2024): 1261. http://dx.doi.org/10.3390/molecules29061261.

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In this study, both practical and theoretical aspects of the solubility of edaravone (EDA) in Deep Eutectic Solvents (DESs) were considered. The solubility of edaravone in some media, including water, can be limited, which creates the need for new efficient and environmentally safe solvents. The solubility of EDA was measured spectrophotometrically and the complex intermolecular interactions within the systems were studied with the COSMO-RS framework. Of the four studied DES systems, three outperformed the most efficient classical organic solvent, namely dichloromethane, with the DES comprisin
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10

Edulji, S. K., and S. T. Nguyen. "Substrate scope in the olefin cyclopropanation reaction catalyzed by m-oxo-bis[(salen)iron(III)] complexes." Pure and Applied Chemistry 76, no. 3 (2004): 645–49. http://dx.doi.org/10.1351/pac200476030645.

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The cyclopropanation of various alkenes with different diazoester compounds was investigated using two different μ-oxo-bis[(salen)iron(III)] complexes, [Fe(3,3',5,5'-tBu4salen)]2O and [Fe(salen)]2O. Ethyl diazoacetate (EDA), tert-butyl diazoacetate (tBDA), and ethyl diazoacetoacetate (EDAA) were used with mono- and disubstituted terminal olefins (styrene and 1,1-diphenyl ethylene, respectively), internal olefin (trans-β-methyl styrene), and an electron-rich alkene (n-butyl vinyl ether). Moderate-to-good cyclopropanation yields were obtained for most substrates.
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11

Singh, Joaquín O., Jorge D. Anunziata та Juana J. Silber. "n–π Electron donor–acceptor complexes. II. Aliphatic amines with dinitrobenzenes". Canadian Journal of Chemistry 63, № 4 (1985): 903–7. http://dx.doi.org/10.1139/v85-150.

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The interaction of several aliphatic amines as n-donors and dinitrobenzenes (DNB) as π-acceptors has been studied in n-hexane. The formation of electron donor – acceptor (EDA) complexes is proposed to explain the spectroscopic behaviour of the mixtures. The stability constants (Ks) for these complexes have been calculated by an iterative procedure. For a given acceptor, the donor strength of RNH2 > R2NH > R3N was found. This order is explained by considering the role that steric effect may play in the EDA complex formation. On the other hand, the fact that for a given donor Ks follows th
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12

Tkachev, V. A., E. I. Mal’tsev, A. V. Vannikov, A. Yu Kryukov, H. H. Hörhold, and J. Klee. "Laser photolysis of polymer EDA complexes including 4,4′-diaminodiphenylmethane derivatives." Research on Chemical Intermediates 13, no. 1 (1990): 7–16. http://dx.doi.org/10.1163/156856790x00021.

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13

Zon, M. A., H. Fernandez, L. Sereno, and J. J. Silber. "The kinetics of formation of electron donor–acceptor complexes. A temperature-jump study." Canadian Journal of Chemistry 68, no. 2 (1990): 278–81. http://dx.doi.org/10.1139/v90-038.

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The kinetics of the Electron Donor–Acceptor (EDA) complex between N,N,N′,N′-tetramethyl-p-phenylenediamine and m-dinitrobenzene in acetonitrile has been studied by the temperature-jump technique. The magnitude of the rate constants of association and dissociation, although relatively large, is well below the diffusion control values. The calculated rates closely coincide with those obtained by chronoamperometry. An entropy control is suggested for this reaction. The results obtained in this work are useful to demonstrate that the concept about EDA complexes being formed by diffusion-controlled
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14

Biasutti, M. A., and Juana J. Silber. "Interaction between tetracyanoethylene and naphthalene in reverse micelles of AOT in n-hexane. The electron-donor properties of AOT." Canadian Journal of Chemistry 74, no. 9 (1996): 1603–8. http://dx.doi.org/10.1139/v96-177.

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The electron donor–acceptor (EDA) interaction between TCNE and naphthalene (Naph) in n-hexane and reverse micelles of AOT in n-hexane was studied by UV–visible spectroscopy with the aim of determining the influence of the micellar media on the EDA interaction. The spectra of the mixtures of TCNE–Naph in n-hexane show two typical maxima at 418 and 534 nm, assigned to the formation of a π–π EDA complex. In the micellar media a new band is observed at 398 nm. When the spectra of TCNE in n-hexane are studied in the presence of AOT two new bands at 398 and 418 nm are detected. These bands are consi
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15

Sima, Jian, Zhijiang Yan, Yaohui Chen, et al. "Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation." Proceedings of the National Academy of Sciences 115, no. 32 (2018): 8173–78. http://dx.doi.org/10.1073/pnas.1800930115.

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Ectodysplasin A (Eda) signaling activates NF-κB during skin appendage formation, but how Eda controls specific gene transcription remains unclear. Here, we find that Eda triggers the formation of an NF-κB–associated SWI/SNF (BAF) complex in which p50/RelB recruits a linker protein, Tfg, that interacts with BAF45d in the BAF complex. We further reveal that Tfg is initially induced by Eda-mediated RelB activation and then bridges RelB and BAF for subsequent gene regulation. The BAF component BAF250a is particularly up-regulated in skin appendages, and epidermal knockout of BAF250a impairs skin a
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16

Pereira, Juscélia C., Luciana M. Lima, Rita C. Alfenas, et al. "Consumption of energy drinks on cardiovascular and metabolic response and performance. Is there an effect?" Archivos de Medicina del Deporte 39, no. 4 (2022): 222–28. http://dx.doi.org/10.18176/archmeddeporte.00094.

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Over the years, the search for nutritional strategies that promote improved sports performance has increased. Among the available options, energy drinks appear as potential nutritional resources for this purpose, because they offer, in addition to caffeine, substances that act synergistically to improve performance, such as taurine, carbohydrates, amino acids, vitamins and minerals, promoting improved performance for both amateur and professional athletes. The aim of the study was to verify the effects of ingesting energy drinks with (ED1) and without carbohydrates (ED0) containing 2 mg·kg-1 o
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17

Neelgund, Gururaj M., Abhay S. Kulkarni, and M. L. Budni. "EDA Complexes of 2,3-Dichloro-1,4-naphthoquinone with Some Substituted Anilines." Monatshefte f�r Chemie / Chemical Monthly 135, no. 4 (2004): 343–55. http://dx.doi.org/10.1007/s00706-003-0128-8.

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18

Jamróz, M. H., J. Cz Dobrowolski, K. Bajdor та M. A. Borowiak. "Ab initio study of the ν(CO2) mode in EDA complexes". Journal of Molecular Structure 349 (квітень 1995): 9–12. http://dx.doi.org/10.1016/0022-2860(95)08696-s.

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19

Dolenc, Darko, and Barbara Modec. "EDA Complexes of N-halosaccharins with N- and O-donor ligands." New Journal of Chemistry 33, no. 11 (2009): 2344. http://dx.doi.org/10.1039/b9nj00263d.

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20

S., P. ARYA, and L. MALLA J. "A Spectrophotometric Method for the Deter-mination of Vanadium as Vanadium(IV)- EDTA Complex." Journal of Indian Chemical Society Vol. 68, Nov 1991 (1991): 635–36. https://doi.org/10.5281/zenodo.6158137.

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Department of Chemistry, Kurukshetra University, Kurukshetra-132 119 <em>Manuscript received 2 April 1991,&nbsp; revised 21 November 1991, accepted 27 November 1991</em> A Spectrophotometric Method for the Deter-mination of Vanadium as Vanadium(IV)- EDTA Complex
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21

Shivji, M. K., and N. B. La Thangue. "Multicomponent differentiation-regulated transcription factors in F9 embryonal carcinoma stem cells." Molecular and Cellular Biology 11, no. 3 (1991): 1686–95. http://dx.doi.org/10.1128/mcb.11.3.1686-1695.1991.

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Murine F9 embryonal carcinoma (F9 EC) stem cells have an E1a-like transcription activity that is down-regulated as these cells differentiate to parietal endoderm. For the adenovirus E2A promoter, this activity requires at least two sequence-specific transcription factors, one that binds the cyclic AMP-responsive element (CRE) and the other, DRTF1, the DNA-binding activity of which is down-regulated as F9 EC cells differentiate. Here we report the characterization of several binding activities in F9 EC cell extracts, referred to as DRTF 1a, 1b and 1c, that recognize the DRTF1 cis-regulatory seq
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Shivji, M. K., and N. B. La Thangue. "Multicomponent differentiation-regulated transcription factors in F9 embryonal carcinoma stem cells." Molecular and Cellular Biology 11, no. 3 (1991): 1686–95. http://dx.doi.org/10.1128/mcb.11.3.1686.

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Murine F9 embryonal carcinoma (F9 EC) stem cells have an E1a-like transcription activity that is down-regulated as these cells differentiate to parietal endoderm. For the adenovirus E2A promoter, this activity requires at least two sequence-specific transcription factors, one that binds the cyclic AMP-responsive element (CRE) and the other, DRTF1, the DNA-binding activity of which is down-regulated as F9 EC cells differentiate. Here we report the characterization of several binding activities in F9 EC cell extracts, referred to as DRTF 1a, 1b and 1c, that recognize the DRTF1 cis-regulatory seq
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23

Mao, Yuezhi, Matthias Loipersberger, Paul R. Horn, et al. "From Intermolecular Interaction Energies and Observable Shifts to Component Contributions and Back Again: A Tale of Variational Energy Decomposition Analysis." Annual Review of Physical Chemistry 72, no. 1 (2021): 641–66. http://dx.doi.org/10.1146/annurev-physchem-090419-115149.

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Quantum chemistry in the form of density functional theory (DFT) calculations is a powerful numerical experiment for predicting intermolecular interaction energies. However, no chemical insight is gained in this way beyond predictions of observables. Energy decomposition analysis (EDA) can quantitatively bridge this gap by providing values for the chemical drivers of the interactions, such as permanent electrostatics, Pauli repulsion, dispersion, and charge transfer. These energetic contributions are identified by performing DFT calculations with constraints that disable components of the inte
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24

Moubayed, Abdallah. "A Complete EDA and DL Pipeline for Softwarized 5G Network Intrusion Detection." Future Internet 16, no. 9 (2024): 331. http://dx.doi.org/10.3390/fi16090331.

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The rise of 5G networks is driven by increasing deployments of IoT devices and expanding mobile and fixed broadband subscriptions. Concurrently, the deployment of 5G networks has led to a surge in network-related attacks, due to expanded attack surfaces. Machine learning (ML), particularly deep learning (DL), has emerged as a promising tool for addressing these security challenges in 5G networks. To that end, this work proposed an exploratory data analysis (EDA) and DL-based framework designed for 5G network intrusion detection. The approach aimed to better understand dataset characteristics,
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25

Muro, Andrés F., Massimo Caputi, Rajalakshmi Pariyarath, Franco Pagani, Emanuele Buratti, and Francisco E. Baralle. "Regulation of Fibronectin EDA Exon Alternative Splicing: Possible Role of RNA Secondary Structure for Enhancer Display." Molecular and Cellular Biology 19, no. 4 (1999): 2657–71. http://dx.doi.org/10.1128/mcb.19.4.2657.

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ABSTRACT The fibronectin primary transcript undergoes alternative splicing in three noncoordinated sites: the cassette-type EDA and EDB exons and the more complex IIICS region. We have shown previously that an 81-nucleotide region within the EDA exon is necessary for exon recognition and that this region contains at least two splicing-regulatory elements: a polypurinic enhancer (exonic splicing enhancer [ESE]) and a nearby silencer element (exonic splicing silencer [ESS]). Here, we have analyzed the function of both elements in different cell types. We have mapped the ESS to the nucleotide lev
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Hamity, M., and R. H. Lema. "The photochemistry of electron donor–acceptor (EDA) complexes in micellar solutions. I. The stilbene–methylviologen system." Canadian Journal of Chemistry 66, no. 7 (1988): 1552–57. http://dx.doi.org/10.1139/v88-252.

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The association constants for the electron donor–acceptor (EDA) complexes formed between both cis-stilbene (cS) and trans-stilbene (tS) as donors and methylviologen (MV+2) as acceptor were determined in ethanol and micellar sodium dodecyl sulfate (SDS) solutions in the range of SDS concentration 0.05–0.1 M. The values obtained in micellar solutions were much higher than those in ethanol and were heavily dependent upon SDS concentration. This effect is due to an increase in the local concentration of the reactants in the micellar pseudophase. The tS fluorescence quenching by MV+2 was also studi
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Ciarrocchi, Carlo, Guido Colucci, Massimo Boiocchi, et al. "Interligand Charge-Transfer Processes in Zinc Complexes." Chemistry 4, no. 3 (2022): 717–34. http://dx.doi.org/10.3390/chemistry4030051.

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Electron donor–acceptor (EDA) complexes are characterized by charge-transfer (CT) processes between electron-rich and electron-poor counterparts, typically resulting in a new absorption band at a higher wavelength. In this paper, we report a series of novel 2,6-di(imino)pyridine ligands with different electron-rich aromatic substituents and their 1:2 (metal/ligand) complexes with zinc(II) in which the formation of a CT species is promoted by the metal ion coordination. The absorption properties of these complexes were studied, showing the presence of a CT absorption band only in the case of ar
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Asaad, Adel N., and Gunnar Aksnes. "Kinetics and Mechanism of the 2+ 2 Cycloaddition of Tetracyanoethylene to 2,5-Dimethyl-2,4-Hexadiene." Zeitschrift für Naturforschung A 43, no. 5 (1988): 435–41. http://dx.doi.org/10.1515/zna-1988-0507.

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The kinetics of the 2 + 2 cycloaddition reaction between tetracyanoethylene and 2,5-dimethyl- 2,4-hexadiene in different solvents has been studied by following the disappearance of the intermediate EDA-complex spectrophotometrically. It is concluded that the EDA-complex is transformed through a concerted cyclicpolar transition state to give the vinyl cyclobutane derivative (III). The effects of various solvents on the reaction rates have been analysed using a multiparameter approach. The thermodynamic parameters (ΔH0 and ΔS0), of EDA-complex formation and the activation parameters (ΔH# and ΔS#
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Leuranguer, Valérie, Robert T. Dirksen, and Kurt G. Beam. "Potentiated L-type Ca2+ Channels Rectify." Journal of General Physiology 121, no. 6 (2003): 541–50. http://dx.doi.org/10.1085/jgp.200308833.

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Strong depolarization and dihydropyridine agonists potentiate inward currents through native L-type Ca2+ channels, but the effect on outward currents is less clear due to the small size of these currents. Here, we examined potentiation of wild-type α1C and two constructs bearing mutations in conserved glutamates in the pore regions of repeats II and IV (E2A/E4A-α1C) or repeat III (E3K-α1C). With 10 mM Ca2+ in the bath and 110 mM Cs+ in the pipette, these mutated channels, expressed in dysgenic myotubes, produced both inward and outward currents of substantial amplitude. For both the wild-type
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Lee, Kwanyoung Y., and Jay K. Kochi. "Charge-transfer structures of aromatic EDA complexes with N-heteroatom-substituted pyridinium cations." Journal of the Chemical Society, Perkin Transactions 2, no. 7 (1992): 1011. http://dx.doi.org/10.1039/p29920001011.

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An, Xiao-De, Hui-Yun Wang, Long-Xue Wang, et al. "Visible-light-induced hydrosulfonylation of alkynes driven by electron-donor–acceptor (EDA) complexes." Tetrahedron Letters 153 (December 2024): 155368. http://dx.doi.org/10.1016/j.tetlet.2024.155368.

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Takemura, Hiroyuki, Saori Nakata, Akiko Inoue, and Ayaka Mishima. "Synthesis of a hexacationic cyclophane and formation of EDA-type host–guest complexes." Journal of Inclusion Phenomena and Macrocyclic Chemistry 77, no. 1-4 (2013): 483–87. http://dx.doi.org/10.1007/s10847-013-0321-2.

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Spange, Stefan, Annett Fährmann, Anett Reuter, Ralph Walther, and Yvonne Zimmermann. "Solvatochromism of carbenium-arene EDA (electrondonor-acceptor) complexes and their behaviour on silica." Journal of Physical Organic Chemistry 14, no. 5 (2001): 271–83. http://dx.doi.org/10.1002/poc.360.

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Ikeda, M. A., and J. R. Nevins. "Identification of distinct roles for separate E1A domains in disruption of E2F complexes." Molecular and Cellular Biology 13, no. 11 (1993): 7029–35. http://dx.doi.org/10.1128/mcb.13.11.7029-7035.1993.

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The adenovirus E1A protein can disrupt protein complexes containing the E2F transcription factor in association with cellular regulatory proteins such as the retinoblastoma gene product (Rb) and the Rb-related p107 protein. Previous experiments have shown that the CR1 and CR2 domains of E1A are required for this activity. We now demonstrate that the CR2 domain is essential for allowing E1A to interact with the E2F-Rb or the E2F-p107-cyclin A-cdk2 complex. Multimeric complexes containing E1A can be detected when the CR1 domain has been rendered inactive by mutation. In addition, the E1A CR1 dom
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Ikeda, M. A., and J. R. Nevins. "Identification of distinct roles for separate E1A domains in disruption of E2F complexes." Molecular and Cellular Biology 13, no. 11 (1993): 7029–35. http://dx.doi.org/10.1128/mcb.13.11.7029.

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The adenovirus E1A protein can disrupt protein complexes containing the E2F transcription factor in association with cellular regulatory proteins such as the retinoblastoma gene product (Rb) and the Rb-related p107 protein. Previous experiments have shown that the CR1 and CR2 domains of E1A are required for this activity. We now demonstrate that the CR2 domain is essential for allowing E1A to interact with the E2F-Rb or the E2F-p107-cyclin A-cdk2 complex. Multimeric complexes containing E1A can be detected when the CR1 domain has been rendered inactive by mutation. In addition, the E1A CR1 dom
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N., Gopalakrishna Bhat, and Narayana B. "Indirect complexometric determination of cadmium(II) using citric acid as a masking agent." Journal of Indian Chemical Society Vol. 89, Apr 2012 (2012): 563–65. https://doi.org/10.5281/zenodo.5761575.

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Doepartment of Chemistry, Srinivas Institute of Technology, Valachil, Mangalore-574 143, Karnataka, Ind1a Department of Chemistry, Mangalore University, Mangalagangothri-571 199, Mangalore, Karnataka. India <em>E-mail</em> : shreedakumar@yahoo.co.in <em>Manuscript received 05 October 2009, revised 07 July 2011&nbsp;accepted 21 July 2011</em> An indirect complexometric method is described for the determination of cadmium(II), citric acid being used as masking agent. Cadmium(II) in a given sample solution is initially complexed with an excess of EDT A and the surplus&nbsp;EDTA is titrated with l
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Theuerkauf, Martin, and John Couwenberg. "The extended downscaling approach: A new R-tool for pollen-based reconstruction of vegetation patterns." Holocene 27, no. 8 (2016): 1252–58. http://dx.doi.org/10.1177/0959683616683256.

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The extended downscaling approach (EDA) is a quantitative method in palynology that aims to detect past vegetation patterns and communities in the landscape. The EDA uses iterative forward modelling to fit vegetation composition to robust landscape patterns by comparing simulated with actually observed pollen deposition. The approach employs a set of pollen records, preferably from medium sized to large lakes or peatlands, as well as maps of robust landscape patterns, such as soils and relief. So far, the EDA has been applied in simple settings with only few taxa. To be able to apply the model
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Muro, Andrés F., Anil K. Chauhan, Srecko Gajovic, et al. "Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan." Journal of Cell Biology 162, no. 1 (2003): 149–60. http://dx.doi.org/10.1083/jcb.200212079.

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Fibronectins (FNs) are multifunctional high molecular weight glycoproteins present in the blood plasma and in the ECMs of tissues. The FN primary transcript undergoes alternative splicing in three regions generating up to 20 main different variants in humans. However, the precise role of the FN isoforms is poorly understood. One of the alternatively spliced exons is the extra domain A (EDA) or extra type III homology that is regulated spatially and temporally during development and aging. To study its in vivo function, we generated mice devoid of EDA exon-regulated splicing. Constitutive exon
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Abdel-Hamid, Refat, Ahmed A. El-Samahy, Abdel-Hafiz El-Taher, and Hussein El-Sagher. "Spectral studies on the interaction of iodine with thiazoles." Canadian Journal of Chemistry 65, no. 3 (1987): 468–72. http://dx.doi.org/10.1139/v87-081.

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The electron donor–acceptor molecular complexes between thiazole and some of its derivatives and iodine in several solvents have been investigated spectrophotometrically at different temperatures. Spectral characteristics, equilibrium constants, K, extinction coefficients, ε, and thermodynamic functions of formation, ΔH0, ΔG0, and ΔS0 have been determined. It was found that the data fit satisfactorily the 1:1 stoichiometric equilibrium: D + I2 = DI2 "outer complex". The EDA complexes obtained are of "n–σ*" type in which the nitrogen atom of thiazole is the donor center. Moreover, the effect of
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Gholamreza Ghane Shalmani, Reza Ghiasi, and Azam Marjani. "EDA, CDA and QTAIM Investigations in the (para-C5H4X) Ir(PH3)3 Iridabenzene Complexes." Russian Journal of Physical Chemistry B 15, S1 (2021): S6—S13. http://dx.doi.org/10.1134/s1990793121090141.

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Lima, Carolina G. S., Thiago de M. Lima, Marcelo Duarte, Igor D. Jurberg, and Márcio W. Paixão. "Organic Synthesis Enabled by Light-Irradiation of EDA Complexes: Theoretical Background and Synthetic Applications." ACS Catalysis 6, no. 3 (2016): 1389–407. http://dx.doi.org/10.1021/acscatal.5b02386.

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Weissflog, W., G. Pelzi, and D. Demus. "EDA Complexes in Liquid Crystalline Mixed Phases of Novel Compounds with Lateral Dicyanoethenyl Substituents." Crystal Research and Technology 21, no. 1 (1986): 117–21. http://dx.doi.org/10.1002/crat.2170210128.

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Lochhead, Marina R., Alexandra D. Brown, Alyssa C. Kirlin, et al. "Structural insights into TAZ2 domain–mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A." Journal of Biological Chemistry 295, no. 13 (2020): 4303–15. http://dx.doi.org/10.1074/jbc.ra119.011078.

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The E-protein transcription factors guide immune cell differentiation, with E12 and E47 (hereafter called E2A) being essential for B-cell specification and maturation. E2A and the oncogenic chimera E2A-PBX1 contain three transactivation domains (ADs), with AD1 and AD2 having redundant, independent, and cooperative functions in a cell-dependent manner. AD1 and AD2 both mediate their functions by binding to the KIX domain of the histone acetyltransferase paralogues CREB-binding protein (CBP) and E1A-binding protein P300 (p300). This interaction is necessary for B-cell maturation and oncogenesis
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Yang, Hong-qiang. "Application of EDA technology in intelligent communication electronic circuit." Journal of Electronic Research and Application 7, no. 5 (2023): 10–15. http://dx.doi.org/10.26689/jera.v7i5.5308.

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Abstract: Electronic design automation (EDA) technology is the product of the computer age and finds its foundation in CAD, CAM, CAT, and CAE. EDA is a kind of auxiliary tool in the design process, which requires the designer to carry out the file design work using hardware language as the foundation. Subsequently, the computer system automatically compiles and integrates the file to achieve simulation goals, and can complete the programming download of the target chip. At present, this technology is widely used in the communication of electronic circuits. This paper summarizes EDA technology
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Jose, Nidhin. "Innovations in Real Time Inventory Management: Leveraging Event Driven Architecture in Modern Retail Supply Chains." European Journal of Computer Science and Information Technology 13, no. 49 (2025): 32–43. https://doi.org/10.37745/ejcsit.2013/vol13n493243.

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This article examines the transformative impact of Event Driven Architecture (EDA) on retail inventory management. As consumer expectations shift toward omnichannel fulfillment and immediate availability, traditional batch processing approaches increasingly fail to meet market demands. It explores how EDA reimagines inventory management through real time event processing, enabling continuous visibility and automated decision making across complex supply networks. It investigates the stream processing technologies powering these systems, primarily Apache Kafka and Apache Flink, alongside the in
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Siddharth Ravikumar. "AI-driven verification: Augmenting engineers in semiconductor EDA workflows." World Journal of Advanced Engineering Technology and Sciences 15, no. 2 (2025): 223–30. https://doi.org/10.30574/wjaets.2025.15.2.0424.

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The semiconductor industry faces mounting verification challenges as chip designs grow increasingly complex, with process nodes shrinking and design elements multiplying. AI-driven verification emerges as a transformative solution, creating a symbiosis between human expertise and machine intelligence rather than replacing engineers. This article explores how AI technologies augment verification workflows through predictive models for testbench generation, advanced anomaly detection systems, and collaborative human-machine partnerships. These innovations enable verification teams to navigate co
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Visnovcova, Zuzana, Lucia Bona Olexova, Nikola Sekaninova, et al. "Spectral and Nonlinear Analysis of Electrodermal Activity in Adolescent Anorexia Nervosa." Applied Sciences 10, no. 13 (2020): 4514. http://dx.doi.org/10.3390/app10134514.

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Anorexia nervosa (AN) is an eating disorder with increasing prevalence in childhood and adolescence. Sympathetic dysregulation is supposed to be the underlying mechanism of increased cardiovascular risk in AN. Thus, we assess the electrodermal activity (EDA) as a non-invasive index of sympathetic cholinergic activity using linear and nonlinear analysis in adolescent AN with the aim of detecting potential biomarkers for AN-linked cardiovascular risk. We examined 25 adolescent girls with AN and 25 age-matched controls. EDA was continuously recorded during a 5-min resting phase. Evaluated paramet
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Bherwani, Harsh. "Machine Learning Models for Cannabis Strain Rating With EDA." International Scientific Journal of Engineering and Management 04, no. 05 (2025): 1–7. https://doi.org/10.55041/isjem03515.

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Abstract: This project investigates the application of machine learning models to predict user ratings of cannabis strains based on features such as flavor, effects, and strain type. Using a dataset of 2,351 strains sourced from Kaggle, the study evaluates three regression models—Linear Regression, Random Forest, and XGBoost—for their predictive accuracy. After preprocessing and feature engineering, including one-hot encoding and CountVectorizer transformations, the models were trained and tested using standard metrics like Mean Squared Error (MSE), R-squared (R²), and Mean Absolute Error (MAE
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Gökdere, Sare, Holm Schneider, Ute Hehr, Laure Willen, Pascal Schneider, and Sigrun Maier-Wohlfart. "Functional and clinical analysis of five EDA variants associated with ectodermal dysplasia but with a hard-to-predict significance." Frontiers in Genetics 13 (July 18, 2022). http://dx.doi.org/10.3389/fgene.2022.934395.

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Deficiency of ectodysplasin A1 (EDA1) due to variants of the gene EDA causes X-linked hypohidrotic ectodermal dysplasia (XLHED), a rare genetic condition characterized by abnormal development of ectodermal structures. XLHED is defined by the triad of hypotrichosis, hypo- or anhidrosis, and hypo- or anodontia. Anhidrosis may lead to life-threatening hyperthermia. A definite genetic diagnosis is, thus, important for the patients’ management and amenability to a novel prenatal treatment option. Here, we describe five familial EDA variants segregating with the disease in three families, for which
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Yan, Tingtao, Jianjing Yang, Kelu Yan, Zhonglei Wang, Bingwen Li, and Jiangwei Wen. "A General Photoactive H‐Bonding EDA Complex Model Drives the Selective Hydrothiolation and Hydroxysulfenylation of Carbonyl Activated Alkenes." Angewandte Chemie, July 2, 2024. http://dx.doi.org/10.1002/ange.202405186.

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Excitation of photoactive electron donor−acceptor (EDA) complexes to generate radical is a promising approach in radical chemistry. In this study, we introduce a new model of H‐bonding EDA complexes for the selective hydrothiolation and hydroxysulfenylation of carbonyl‐activated alkenes with diverse thiols under visible light conditions. The reliability of this H‐bonding EDA complex model has been confirmed by meticulous experimental and theoretical calculations. Mechanistic investigations have revealed the significant influence of the solvent in determining whether the excitation of photoacti
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