Thematische Bibliographien / COX-2 selective inhibitor

Inhaltsverzeichnis

  1. Zeitschriftenartikel
  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte
  6. Berichte der Organisationen

Auswahl der wissenschaftlichen Literatur zum Thema „COX-2 selective inhibitor“

Autor: Grafiati
Veröffentlicht am 7. Juni 2025
Zuletzt aktualisiert am 2. August 2025

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Zeitschriftenartikel zum Thema "COX-2 selective inhibitor"

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NAKAMURA, Hideo. "Cyclooxygenase (COX)-2 selective inhibitors: aspirin, a dual COX-1/COX-2 inhibitor, to COX-2 selective inhibitors." Folia Pharmacologica Japonica 118, no. 3 (2001): 219–30. http://dx.doi.org/10.1254/fpj.118.219.

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Eibl, Guido, Yasunori Takata, Laszlo G. Boros, et al. "Growth Stimulation of COX-2–Negative Pancreatic Cancer by a Selective COX-2 Inhibitor." Cancer Research 65, no. 3 (2005): 982–90. http://dx.doi.org/10.1158/0008-5472.982.65.3.

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Abstract Cyclooxygenase 2 (COX-2) inhibitors are promising antiangiogenic agents in several preclinical models. The aim of the present study was to evaluate the effect of selective COX-2 inhibitors on vascular endothelial growth factor (VEGF) production in vitro and angiogenesis and growth of pancreatic cancer in vivo, focusing on putative differences between COX-2–negative and COX-2–positive tumors. VEGF production and angiogenesis in vitro were determined by ELISA and endothelial cell migration assay. To determine whether the effect of COX-2 inhibitors was mediated by peroxisome proliferator
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&NA;. "Rofecoxib: a selective COX-2 inhibitor." Drugs & Therapy Perspectives 15, no. 2 (2000): 1–5. http://dx.doi.org/10.2165/00042310-200015020-00001.

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Martina, Shaunta‘ D., Kimi S. Vesta, and Toni L. Ripley. "Etoricoxib: A Highly Selective COX-2 Inhibitor." Annals of Pharmacotherapy 39, no. 5 (2005): 854–62. http://dx.doi.org/10.1345/aph.1e543.

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OBJECTIVE: To review the available literature evaluating the pharmacology, pharmacokinetics, clinical efficacy, and adverse effects of etoricoxib, a highly selective cyclooxygenase-2 (COX-2) inhibitor that is not currently approved for use in the US. DATA SOURCES: Literature retrieval was accessed through MEDLINE (1966–December 2004), Current Contents (1998–December 2004), and Cochrane Library (4th quarter 2004). References from retrieved articles, information from the manufacturer, and abstracts from the American College of Rheumatology and Annual European Congress of Rheumatology meetings we
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Degraeve, Frédéric, Manlio Bolla, Stéphanie Blaie, et al. "Modulation of COX-2 Expression by Statins in Human Aortic Smooth Muscle Cells." Journal of Biological Chemistry 276, no. 50 (2001): 46849–55. http://dx.doi.org/10.1074/jbc.m104197200.

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Cyclooxygenase (COX)-2 and COX-1 play an important role in prostacyclin production in vessels and participate in maintaining vascular homeostasis. Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is crucial in cholesterol biosynthesis. Recently, cholesterol-independent effects of statins have been described. In this study, we evaluated the effect of two inhibitors of HMG CoA reductase, mevastatin and lovastatin, on the production of prostacyclin and the expression of COX in human aortic smooth muscle cells. Treatment of cells with 25 μmmevastatin or lo
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Jeger, Raban V., Jeffrey D. Greenberg, Krishnan Ramanathan, and Michael E. Farkouh. "Lumiracoxib, a highly selective COX-2 inhibitor." Expert Review of Clinical Immunology 1, no. 1 (2005): 37–45. http://dx.doi.org/10.1586/1744666x.1.1.37.

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&NA;. "Rofecoxib: a selective and effective COX-2 inhibitor." Drugs & Therapy Perspectives 18, no. 2 (2002): 1–3. http://dx.doi.org/10.2165/00042310-200218020-00001.

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Miller, Jane L. "Second selective COX-2 inhibitor receives marketing approval." American Journal of Health-System Pharmacy 56, no. 13 (1999): 1294. http://dx.doi.org/10.1093/ajhp/56.13.1294a.

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Takahashi, Toshiyuki, and Mitsuo Miyazawa. "N-Caffeoyl serotonin as selective COX-2 inhibitor." Bioorganic & Medicinal Chemistry Letters 22, no. 7 (2012): 2494–96. http://dx.doi.org/10.1016/j.bmcl.2012.02.002.

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Zhu, Xi-Tian, Lei Chen, and Jian-Hua Lin. "Selective COX-2 inhibitor versus non-selective COX-2 inhibitor for the prevention of heterotopic ossification after total hip arthroplasty." Medicine 97, no. 31 (2018): e11649. http://dx.doi.org/10.1097/md.0000000000011649.

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Dissertationen zum Thema "COX-2 selective inhibitor"

1

Davies, Richard. "Effect of selective COX-2 inhibitors on hepatic progenitor cells and the pathologies of experimental hepatocarcinogenesis." University of Western Australia. School of Medicine and Pharmacology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0190.

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[Truncated abstract] Hepatocellular carcinoma (HCC) is the major malignancy complicating chronic liver disease. New therapies for the prevention of HCC are required due to the limited success and high tumour recurrence rates of existing treatments. Emerging evidence suggests that HCC arise from the transformation of adult liver progenitor cells (LPCs), which have the capacity to differentiate into hepatocytes and biliary cells during liver regeneration. LPC activation precedes neoplasia in experimental hepatocarcinogenesis. LPCs share antigenic epitopes with HCCs, including α-fetoprotein (AFP)
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Li, Zhigang. "Suppression of N-nitrosomethylbenzylamine(NMBA)-induced esophageal tumorigenesis in F344 rats by JTE-522,a selective COX-2 inhibitor." Kyoto University, 2002. http://hdl.handle.net/2433/149320.

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Silva, Aline Alves da. "Avaliação clínica de Rattus norvegicus após terapia antiinflamatória com inibidor seletivo ou não para COX-2 por extrapolação alométrica." Universidade Federal de Santa Maria, 2004. http://repositorio.ufsm.br/handle/1/4112.

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The anti-inflammatories no esteroidais (AINEs) they are the drugs of larger prescription all over the world, for humans and for animals. They combat the inflammation, the pain, the temperature increase, could also inhibit the aggregation plaques. They act inhibiting the production of the acid araquidônico and ciclooxigenases (COXs) decreasing like this, the prostaglandins production. They become separated in inhibitors no selective for COX-1 and 2, being those the most traditional; and in selective inhibitors for COX-2, considered more modern drugs. AINEs no selective they reduce the productio
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King, Liam Denson. "COX-2 selective inhibitors as an adjunct to radiotherapy." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/382714.

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Background Radiotherapy is a common treatment modality for many solid state cancers including prostate cancer (PCa). Unfortunately, up to 50% of patients that undergo radiotherapy for localised PCa will develop biochemical failure. Acute and delayed toxicities and tumour resistance are two key factors limiting the effectiveness of many cancer treatments, including radiotherapy. Toxicity rates in PCa patients that accompany radiotherapy are high with 80% of men experiencing some degree of urinary frequency, 40% bowel frequency and chronic impotence is usual. Furthermore, tumour radioresistance
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Hasan, Kamrul. "Clclo-oxygenase (COX) isoforms in the cardiovascular system : Implications for the future of COX-2 selective inhibitors." Thesis, Imperial College London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536024.

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Chen, Qilei. "Discovery of COX-2 selective inhibitors from saussurea laniceps using an enzyme-anchored nanomagnetic ligand fishing platform." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/708.

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Serious cardiovascular side effects are reported from synthetic cyclooxygenase-2 (COX-2) selective nonsteroidal anti-inflammatory drugs, the most common medication for rheumatoid arthritis (RA) and osteoarthritis (OA). Natural products from herbal medicine are inspirational source of safe and effective remedy due to its distinguished chemical diversity. Nanomagnetic ligand fishing using enzyme-anchored-magnetic nanoparticles (MNPs) is an advanced selective bioseparation strategy based on macromolecular target-ligand binding, which can screen enzyme inhibitors from complex mixtures. "Snow lotus
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Gu, Baoying. "Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy : effects of nimesulide." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112627.

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Wernicke's encephalopathy is a neuropsychiatric disorder resulting from thiamine deficiency (TD) and is characterized by neuronal loss, astrocytic proliferation and microglial activation. Cyclooxygenases (COX) are enzymes which catalyze the first step in the synthesis of prostanoids. COX-1 is expressed constitutively and COX-2 is the inducible isoform. Groups of TD rats and pair-fed controls were killed at presymptomatic and symptomatic stages of encephalopathy. Cresyl violet and NeuN staining showed decreased numbers of neuronal cells in vulnerable regions (medial thalamus and inferior collic
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Sawdy, Robert John. "The role of the type-2 isoform of the cyclooxygenase enzyme (COX-2) in human parturition : potential benefits of selective COX-2 inhibitors in the management of preterm labour." Thesis, Imperial College London, 2003. http://hdl.handle.net/10044/1/11444.

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Borges, Alexandre [UNESP]. "Estudos de modelagem molecular de lignanas em complexos com ciclooxigenases-1 e 2." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/140137.

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Submitted by ALEXANDRE BORGES null (alex.brgs@hotmail.com) on 2016-06-28T19:11:21Z No. of bitstreams: 1 ESTUDOS DE MODELAGEM MOLECULAR DE LIGNANAS EM COMPLEXOS COM CICLOOXIGENASES-1 E 2.pdf: 4325586 bytes, checksum: 2f6ab56677aea7746bd28dad4b24ea23 (MD5)<br>Approved for entry into archive by Ana Paula Grisoto (grisotoana@reitoria.unesp.br) on 2016-06-29T17:41:12Z (GMT) No. of bitstreams: 1 borges_a_dr_ilha.pdf: 4325586 bytes, checksum: 2f6ab56677aea7746bd28dad4b24ea23 (MD5)<br>Made available in DSpace on 2016-06-29T17:41:12Z (GMT). No. of bitstreams: 1 borges_a_dr_ilha.pdf: 4325586 bytes,
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Borges, Alexandre. "Estudos de modelagem molecular de lignanas em complexos com ciclooxigenases-1 e 2 /." Ilha Solteira, 2016. http://hdl.handle.net/11449/140137.

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Orientador: Rosangela da Silva de Laurentiz<br>Resumo: Os inibidores seletivos da ciclooxigenase-2 (COX-2), como o rofecoxibe (2) e o celecoxibe (1), formam uma importante classe de medicamentos anti-inflamatórios desenvolvidos a partir da descoberta das duas isoformas das ciclooxigenases (COX-1 e COX-2) na década de 1979. A isoforma 1 esta relacionada com a citoproteção gástrica, agregação plaquetária e função renal e a isoforma 2 relacionada a processos inflamatórios. Estes inibidores seletivos apesar de não apresentarem os efeitos colaterais (ulceras e gastrites) dos anti-inflamatórios não
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Bücher zum Thema "COX-2 selective inhibitor"

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Vane, John, and Jack Botting, eds. Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6.

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R, Vane John, Botting Jack H, and William Harvey Research Conference (1997 : Cannes, France), eds. Selective COX-2 inhibitors: Pharmacology, clinical effects and therapeutic potential : proceedings of a conference held on March 20-21, 1997, in Cannes, France. Kluwer Academic, 1998.

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R, Vane John, Botting Regina M, William Harvey Research Conference (1997 : Phuket, Thailand), and William Harvey Research Conference (1998 : Boston, Mass.), eds. Clinical significance and potential of selective COX-2 inhibitors: The combined proceedings of the William Harvey Conferences held in Phuket, Thailand, on 18-19 September, 1997 and in Boston, USA, on 23-24 April, 1998, supported by an educational grant from Boehringer Ingelheim. William Harvey Press, 1998.

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Vane, John. Selective COX-2 Inhibitors. Springer, 2012.

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Therapeutic Roles Of Selective Cox-2 Inhibitors. WILLIAM HARVEY PRESS, 2001.

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Simon, Lee S., and Marc C. Hochberg. Non-steroidal anti-inflammatory drugs. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0030.

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Non-steroidal anti-inflammatory drugs (NSAIDs) are a chemically diverse group of compounds that share three cardinal characteristics: they are anti-inflammatory, analgesic, and antipyretic. They are approved by regulatory authorities for the treatment of patients with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, and some forms of juvenile idiopathic arthritis. There are at least 20 chemically different NSAIDs currently available in Europe and the United States. These include not only the ‘traditional’ non-selective cyclooxygenase (COX) inhibitors that inhibit both
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Vane, Sir John, ed. Clinical Significance And Potential Of Selective Cox-2 Inhibitors. WILLIAM HARVEY PRESS, 1998.

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Sir John R. Vane (Editor) and Jack H. Botting (Editor), eds. Selective COX-2 Inhibitors: Pharmacology, Clinical Effects and Therapeutic Potential. Springer, 1998.

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Botting, Jack H., and Sir John R. Vane. Selective COX-2 Inhibitors: Pharmacology, Clinical Effects and Therapeutic Potential. Springer, 2012.

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Selective COX-2 inhibitors: Pharmacology, clinical effects, and therapeutic potential : proceedings of a conference held on March 20-21, 1997, in Cannes, France. Kluwer Academic, 1998.

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Buchteile zum Thema "COX-2 selective inhibitor"

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Lau, C. K., W. C. Black, M. Belley, et al. "From Indomethacin to a Selective Cox-2 Inhibitor." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4899-1813-0_11.

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Bolten, W. "Clinical experience with meloxicam, a selective COX-2 inhibitor." In New Targets in Inflammation. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-011-5386-7_12.

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Akarsu, Eyup S., Soner Mamuk, and Sibel Arat. "Variable Antipyretic Effect of SC-58236, a Selective Cyclooxygenase (COX)-2 Inhibitor, in Rats." In Advances in Experimental Medicine and Biology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9194-2_28.

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Kalgutkar, Amit S., Brenda C. Crews, Scott W. Rowlinson, Carlos Garner, and Lawrence J. Marnett. "Discovery of a New Class of Selective Cyclooxygenase-2 (COX-2) Inhibitor that Covalently Modifies the Isozyme." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4793-8_21.

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Vane, J. R., and R. M. Botting. "Mechanism of action of anti-inflammatory drugs: an overview." In Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6_1.

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Gryglewski, R. J. "Aspirin-induced asthma and cyclooxygenases." In Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6_10.

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Fenner, H. "New classification of aspirin-like drugs." In Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6_11.

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Ford-Hutchinson, A. W. "New highly selective COX-2 inhibitors." In Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6_12.

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Isakson, P., B. Zweifel, J. Masferrer, et al. "Specific COX-2 inhibitors: from bench to bedside." In Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6_13.

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Furst, D. E. "Meloxicam: selective COX-2 inhibition in clinical practice." In Selective COX-2 Inhibitors. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4872-6_14.

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Konferenzberichte zum Thema "COX-2 selective inhibitor"

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Powell, Daniel E. "Methodology for Designing Field Tests to Evaluate Different Types of Corrosion Inhibitors in Crude Oil Production Systems." In CORROSION 2004. NACE International, 2004. https://doi.org/10.5006/c2004-04367.

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Abstract This paper presents a methodology for designing field tests to assess the relative performance of inhibitors and other chemical products, which are used to control corrosion associated with crude oil production. The same corrosion inhibitor injection points and corrosion monitoring points can be used for (1) routine operations, and for (2) field performance tests of candidate products. Field tests, which assess the performance of individual products for three phase fluids or wet gas production, require precise step changes in the chemical treatments rates in order to accurately determ
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Hill, R. T., F. A. Ramirez, B. Monty, and G. Palanivel. "Material Selection Assessment for Topside Process Equipment for Production Fluids with High CO2 Content." In CORROSION 2011. NACE International, 2011. https://doi.org/10.5006/c2011-11118.

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Abstract During recent years, in the exploration for new oil and gas sources, the tendency towards developing offshore fields in more stringent environments has increased. Operators are now developing deep water, high pressure, high temperature, and high CO2 fields. This tendency has created numerous challenges to the project initial cost (CAPEX) and subsequent operational cost (OPEX). The material selection is critical for such fields showing high CO2 content. Although the initial capital cost for using carbon steel may be much lower than that of a corrosion resistant alloy (CRA), the total c
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Seiersten, Marion. "Corrosion of Mild Steel in Concentrated Monoethylene Glycol (MEG)." In CORROSION 2021. AMPP, 2021. https://doi.org/10.5006/c2021-16701.

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Abstract Material selection for Monoethylene glycol (MEG) regeneration units is a challenge due to the high temperature combined with high salt content. The oxygen level is low, and carbon steel is a cost-effective choice. The corrosion rate of carbon steel is too high in neutral or acidic conditions, but in alkaline solution, C-steel might be an alternative even without the use of film forming corrosion inhibitor. The corrosion rate of carbon steel in ca. 97 wt% MEG at 120 °C, is quite low in alkaline solutions. If the MEG solution contains more than 2 mmol/kg alkalinity, the corrosion rate i
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Fartash, Roozbeh, Saba NavabZadeh, Habib Amirkhizi, and Mobin Salasi. "A Systematic Approach toward Selection of Cost-Effective and Corrosion Resistant Materials and Corrosion Inhibition and Protection Methods by Using Corrosion Prediction Models." In CORROSION 2010. NACE International, 2010. https://doi.org/10.5006/c2010-10368.

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Abstract A methodology was developed to identify and choose the most cost-effective material and also appropriate remedial corrosion inhibition and protection methods by using 4 reputable corrosion prediction models in dry and wet oil &amp; gas pipeline containing CO2 with and without H2S. The importance of the corrosion allowance factor for the basic design stage, initiated this project as an active study in NEC(2) in early 2008. Observed discrepancies in the predicted corrosion rates by different corrosion prediction models for identical conditions, aimed the group to develop a methodology t
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Luft, H. B., K. E. Szklarz, J. Nowinka, and H. Skrzypek. "Evaluating Fitness-for-Purpose of Coiled Tubing for Underbalanced Drilling of Sour Wells." In CORROSION 2002. NACE International, 2002. https://doi.org/10.5006/c2002-02054.

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Abstract A multi-year joint industry program (JIP) has been completed involving an experimental testing program to evaluate the fitness-for-purpose of high-strength low-alloy steel coiled tubing (CT) in under-balanced drilling of sour oil and gas wells. The primary focus is the cold-worked material response to sour well conditions when subjecting the tubing to multiple cycles of plastic tension and compression strains in the range of 2% to 3%. The material performance and/or degradation parameters measured include low-cycle corrosion-fatigue (LCCF) life, critical stress corrosion cracking (SCC
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Barker, Richard, Michael Bryant, Frederick Pessu, and Anne Neville. "Determining the Behavior of Sulfur Compounds in Controlling Preferential Weld Corrosion in CO2-Saturated Brine." In CORROSION 2014. NACE International, 2014. https://doi.org/10.5006/c2014-4213.

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Abstract This paper presents the application of white light interferometry as a new complimentary technique in addition to zero resistance ammetry (ZRA) and the linear polarization resistance (LPR) technique to determine regions of selective attack on 1% Ni welds in CO2-saturated environments. Un-segmented electrodes consisting of a parent material, heat affected zone (HAZ) and weld were subjected to long duration immersion tests and subsequently 3D profiled using white light interferometry to assess which regions (if any) preferentially corroded. In parallel tests, a multi-array electrode was
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Amdekar, Sarika, and Vinod Singh. "Lactobacillus acidophilus A Selective COX 2 Inhibitor Protected Ovary and Testis in Induced Arthritic Model." In Annual International Conference on Advances in Biotechnology. Global Science & Technology Forum (GSTF), 2013. http://dx.doi.org/10.5176/2251-2489_biotech13.71.

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Rao, Chinthalapally V., Suresh Guruswamy, Jagan Mohan R. Patlolla, Naveena Janakiram, and Venkat S. Malisetty. "Abstract A53: Chemoprevention of colon cancer by PBIT, an iNOS‐selective inhibitor, administered alone or in combination with low‐doses of celecoxib, a COX‐2 selective inhibitor." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Dec 6–9, 2009; Houston, TX. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1940-6207.prev-09-a53.

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Tripathi, Shweta, Sudhir Chandna, B. S. Dwarkanath, Daman Saluja, and Madhu Chopra. "Abstract A37: Mechanistic study involving antiproliferative effect of Etoricoxib, a highly selective COX‐2 inhibitor on human cancer cell lines." In Abstracts: First AACR International Conference on Frontiers in Basic Cancer Research--Oct 8–11, 2009; Boston MA. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.fbcr09-a37.

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Curtis, SP, J. Maldonado-Cocco, BR Losada, et al. "FRI0030 Treatment with etoricoxib (mk-0663), a cox-2 selective inhibitor, resulted in maintenance of clinical improvement in rheumatoid arthritis." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.1159.

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Berichte der Organisationen zum Thema "COX-2 selective inhibitor"

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Splitter, Gary, Zeev Trainin, and Yacov Brenner. Lymphocyte Response to Genetically Engineered Bovine Leukemia Virus Proteins in Persistently Lymphocytic Cattle from Israel and the U.S. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570556.bard.

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The goal of this proposal was to identify proteins of BLV recognized by lymphocyte subpopulations and determine the contribution of these proteins to viral pathogenesis. Our hypothesis was that BLV pathogenesis is governed by the T-cell response and that the immune system likely plays an important role in controlling the utcome of infection. Our studies presented in ths final report demonstrate that T cell competency declines with advancing stages of infection. Dramatic differences were observed in lymphocyte proliferation to recombinant proteins encoded by BLV gag (p12, p15, and p24) and env
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2

Sadka, Avi, Mikeal L. Roose, and Yair Erner. Molecular Genetic Analysis of Citric Acid Accumulation in Citrus Fruit. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7573071.bard.

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The acid content of the juice sac cells is a major determinant of maturity and fruit quality in citrus. Many citrus varieties accumulate acid in concentrations that exceed market desires, reducing grower income and consumer satisfaction. Pulp acidity is thought to be dependent on two mechanisms: the accumulation of citric acid in the vacuoles of the juice sac cells, and acidification of the vacuole. The major aim of the project was to direct effort toward understanding the mechanism of citric acid accumulation in the fruit. The following objectives were suggested: Measure the activity of enzym
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3

Ohad, Itzhak, and Himadri Pakrasi. Role of Cytochrome B559 in Photoinhibition. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7613031.bard.

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The aim of this research project was to obtain information on the role of the cytochrome b559 in the function of Photosystem-II (PSII) with special emphasis on the light induced photo inactivation of PSII and turnover of the photochemical reaction center II protein subunit RCII-D1. The major goals of this project were: 1) Isolation and sequencing of the Chlamydomonas chloroplast psbE and psbF genes encoding the cytochrome b559 a and b subunits respectively; 2) Generation of site directed mutants and testing the effect of such mutation on the function of PSII under various light conditions; 3)
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