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1

Aderinola, Musefiu, Bokolo Abovie, Festus Okosi, Igoniderigha Daniel, and G. F. Odubo. "Analysis of Different Ways of Crosstalk Measurement in GSM Network." International Journal of Reconfigurable and Embedded Systems (IJRES) 5, no. 2 (2016): 106. http://dx.doi.org/10.11591/ijres.v5.i2.pp106-110.

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<p>Crosstalk is one of the problems that affect the performance operation of global system mobile (GSM) network. Among the effect of crosstalk are call mute, call drop, wire propagation delay, dynamic power dissipation etc. Crosstalk is an undesirable signal arising due to the coupling capacitances between adjacent interconnecting wires and measured in decibel. In this paper some literature were reviewed and different ways of measuring crosstalk such as Near end croosstalk (NEXT), far end crosstalk (FEXT), Power sum crosstalk (PSNEXT) and alien crosstalk (AXT) were analyzed. </p>
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2

Hussein, Ahmed Ali. "Using rectangular trace to reduce the crosstalk of the coupled microstrip lines." International Journal of Engineering & Technology 5, no. 1 (2015): 7. http://dx.doi.org/10.14419/ijet.v5i1.4771.

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New electronic products must have high-speed, small size and lower voltages supply. With such layout, signal integrity (SI) becomes an actual important issue because sensitive equipment is affected on electromagnetic interference (EMI). Crosstalk is a major factor in signal integrity (SI) of printed circuit boards (PCBs). Crosstalk noise is usually represented in terms of Near-End crosstalk (NEXT) and Far-End crosstalk (FEXT). Crosstalk is a common problem that degrades circuit performance. To reduce this problem, via hole-fences connected by guard trace between double microstrip lines are use
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3

Hangleiter, Dominik. "Crosstalk diagnosis for the next generation of quantum processors." Quantum Views 4 (October 29, 2020): 46. http://dx.doi.org/10.22331/qv-2020-10-29-46.

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4

Venne, A. Saskia, Laxmikanth Kollipara, and René P. Zahedi. "The next level of complexity: Crosstalk of posttranslational modifications." PROTEOMICS 14, no. 4-5 (2014): 513–24. http://dx.doi.org/10.1002/pmic.201300344.

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5

Sarovar, Mohan, Timothy Proctor, Kenneth Rudinger, Kevin Young, Erik Nielsen, and Robin Blume-Kohout. "Detecting crosstalk errors in quantum information processors." Quantum 4 (September 11, 2020): 321. http://dx.doi.org/10.22331/q-2020-09-11-321.

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Crosstalk occurs in most quantum computing systems with more than one qubit. It can cause a variety of correlated and nonlocal crosstalk errors that can be especially harmful to fault-tolerant quantum error correction, which generally relies on errors being local and relatively predictable. Mitigating crosstalk errors requires understanding, modeling, and detecting them. In this paper, we introduce a comprehensive framework for crosstalk errors and a protocol for detecting and localizing them. We give a rigorous definition of crosstalk errors that captures a wide range of disparate physical ph
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6

Lee, Won-Jong, Dong-Gyu Kim, and Woo-Su Kim. "Enhancing the Electromagnetic Interference Performance of Vehicle Connectors Using Wave-Shaped Techniques." Korea Industrial Technology Convergence Society 28, no. 4 (2023): 189–95. http://dx.doi.org/10.29279/jitr.2023.28.4.189.

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This study shows the improvement in sufficient crosstalk and electromagnetic interference (EMI) performance by designing the terminal structure of a wave-shaped connector. In addition, impedance was improved without reducing the size of the terminal width of the connector. The operating range of the designed connector extended up to 6 GHz, providing 15-20 dB improvement in far-end crosstalk (FEXT) performance and 10-35 dB improvement in near-end crosstalk (NEXT) compared with traditional straight terminal methods.
 The EMI performance also improved by approximately 20 μV/m when applying t
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7

V, Yokesh. "On the Design of a Stepped Mixed Signal Transmission Line with Defected Microstrip Structure for High-Frequency PCB Traces." JOURNAL OF HIGH-FREQUENCY COMMUNICATION TECHNOLOGIES 2, no. 01 (2024): 120–29. http://dx.doi.org/10.58399/rzrq1838.

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The paper addresses the challenge of crosstalk in neighboring paths on PCBs, emphasizing its growing importance with the advancement of electronic circuits in terms of speed and frequency. The proposed solution involves the introduction of a novel W-shaped Defected Microstrip Structure (DMS) on a step-shaped coupled transmission lines to mitigate near-end crosstalk (NEXT) and far-end crosstalk (FEXT) using mixed signal input. A novel W-shaped defective microstrip structure (DMS) that is etched on step-shaped coupled transmission lines. The proposed technique focuses on minimizing the electroma
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8

Orozco-Galindo, Bianca Viviana, Blanca Sánchez-Ramírez, Cynthia Lizeth González-Trevizo, Beatriz Castro-Valenzuela, Luis Varela-Rodríguez, and M. Eduviges Burrola-Barraza. "Folliculogenesis: A Cellular Crosstalk Mechanism." Current Issues in Molecular Biology 47, no. 2 (2025): 113. https://doi.org/10.3390/cimb47020113.

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In vitro embryo production has accelerated in the cattle industry in recent years. Because women are similar to cows, this represents an opportunity to improve women’s reproductive protocols. This review focuses on crosstalk communication during folliculogenesis for an in-depth understanding of the events involved in developing the oocyte competence necessary to generate an embryo after fertilization. This knowledge can be used to improve oocytes in in vitro maturation cultures, which would allow us to obtain oocytes of high quality and competence, resulting in successful pregnancies in both w
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9

Jin, Jieqi, Mengkai Guang, Anthony Chukwunonso Ogbuehi, et al. "Shared Molecular Mechanisms between Alzheimer’s Disease and Periodontitis Revealed by Transcriptomic Analysis." BioMed Research International 2021 (April 1, 2021): 1–22. http://dx.doi.org/10.1155/2021/6633563.

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Objective. To investigate the genetic crosstalk mechanisms that link periodontitis and Alzheimer’s disease (AD). Background. Periodontitis, a common oral infectious disease, is associated with Alzheimer’s disease (AD) and considered a putative contributory factor to its progression. However, a comprehensive investigation of potential shared genetic mechanisms between these diseases has not yet been reported. Methods. Gene expression datasets related to periodontitis were downloaded from the Gene Expression Omnibus (GEO) database, and differential expression analysis was performed to identify d
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10

Heliotis, George, Lowell-Panayotis Dimos, Ioannis Kordoulis, and George Agapiou. "Performance and Limitations of VDSL2-based Next Generation Access Networks." Journal of Telecommunications and Information Technology, no. 1 (March 30, 2013): 98–102. http://dx.doi.org/10.26636/jtit.2013.1.1207.

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In this paper, we first briefly review the main operational aspects of FTTC (xPON)/VDSL2 access networks. Then, we present performance measurements with respect to network sub loop operating length and VDSL2 operational profiles (8b, 12a, 17a), studying the rates that can be achieved at different scenarios. We then provide results of the effect of stationary crosstalk and non-stationary impulse noise on the provisioned service in an operating VDSL2 access network.
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11

Tang, Pu, Jing Xiao, and Ming Tao. "Thermal Crosstalk Analysis of Phase Change Memory Considering Thermoelectric Effect and Thermal Boundary Resistance." Journal of Physics: Conference Series 2624, no. 1 (2023): 012020. http://dx.doi.org/10.1088/1742-6596/2624/1/012020.

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Abstract Phase change memory (PCM) has emerged as a promising memory for next-generation applications due to its high-speed read and write capabilities as well as non-volatility. However, as PCM scales down to smaller feature sizes, it faces the challenge of thermal crosstalk. During the reset operation, a large amount of heat is generated and dissipated in the PCM array, potentially affecting adjacent memory cells, compromising device stability, and limiting high-density integration. To accurately investigate the thermal crosstalk in the PCM array, the conventional finite element model of the
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12

Sathyakam, P. Uma, P. S. Mallick, and Paridhi Singh. "Geometry-Based Crosstalk Reduction in CNT Interconnects." Journal of Circuits, Systems and Computers 29, no. 06 (2019): 2050094. http://dx.doi.org/10.1142/s0218126620500942.

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This paper proposes novel triangular cross-sectioned geometry of carbon nanotube (CNT) bundles for crosstalk and delay reduction in CNT bundle interconnects for VLSI circuits. First, we formulate the equivalent single conductor (ESC) transmission line models of the interconnects. Through SPICE analysis of the ESC circuits, we find the propagation delays of the proposed CNT bundles. Next, we model the capacitively coupled interconnects for crosstalk analysis. It is found that the coupling capacitance of triangular CNT bundle is 29% lesser than the traditionally used square CNT bundles. Further,
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13

von Allmen, Douglas C., Lauren J. Francey, Garrett M. Rogers, et al. "Circadian Dysregulation: The Next Frontier in Obstructive Sleep Apnea Research." Otolaryngology–Head and Neck Surgery 159, no. 6 (2018): 948–55. http://dx.doi.org/10.1177/0194599818797311.

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Objective To review the effects of the circadian clock on homeostasis, the functional interaction between the circadian clock and hypoxia-inducible factors, and the role of circadian dysregulation in the progression of cardiopulmonary disease in obstructive sleep apnea (OSA). Data Sources The MEDLINE database was accessed through PubMed. Review Methods A general review is presented on molecular pathways disrupted in OSA, circadian rhythms and the role of the circadian clock, hypoxia signaling, crosstalk between the circadian and hypoxia systems, the role of the circadian clock in cardiovascula
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14

Oliveira, Ramon Alves, and Helder May Nunes da Silva Oliveira. "Multi-Criteria, crosstalk-sensitive flexible topology approach for routing in SDM-EONs." Journal of Internet Services and Applications 16, no. 1 (2025): 43–57. https://doi.org/10.5753/jisa.2025.5041.

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In recent years, the demand for high-capacity, flexible optical networks has driven significant advancements in network design, especially within Space-Division Multiplexing Elastic Optical Networks (SDM-EONs). These networks are expected to efficiently handle the increasing volume of data traffic while minimizing issues such as inter-core crosstalk and request blocking, which can degrade performance. To address these challenges, we propose an RMSSA (Routing, Modulation, Spectrum, and Space Assignment) approach specifically for SDM-EONs. Our method dynamically calculates link-weight across the
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15

Zhang, Qiming, Xiaoquan Hua, Jianghui Kang, et al. "P‐9.22: Research on Light‐field Naked‐eye 3D Display Based on Diffraction Optics." SID Symposium Digest of Technical Papers 56, S1 (2025): 1388–91. https://doi.org/10.1002/sdtp.19094.

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This paper studies the naked‐eye 3D display technology based on diffractive optics. A viewpoint modulation plate was designed and fabricated, utilizing the shining Fresnel‐type diffraction optical element (FDOE), achieving a large field of view and low crosstalk for autostereoscopic 3D display. First, the FDOE structure was designed through the phase recovery algorithm to achieve four‐view naked‐eye 3D display, and its optical properties were verified through experiments. Next, a modulation plate containing multiple viewpoints was designed, and its viewing angle light‐field distribution, diffr
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16

Singh, Rima, Natalie Yousefian, Nina Steele, and Christopher Halbrook. "Abstract LB454: Targeting the epithelial-stromal cell crosstalk in metastatic pancreatic cancer." Cancer Research 85, no. 8_Supplement_2 (2025): LB454. https://doi.org/10.1158/1538-7445.am2025-lb454.

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Abstract Pancreatic Ductal Adenocarcinoma (PDA) is a devastating disease with a 5-year survival of 13%. However, if detected at an earlier stage, PDA has a 5-year survival of more than 30%. Accordingly, the dismal prognosis can be ascribed to late diagnosis after the disease has metastasized, most frequently to the liver. However, work to develop treatments have been largely designed for primary PDA cells residing in hypoxic & nutrient deficient tumor microenvironment (TME) of the pancreas. It is likely that these treatments will not be equally effective against metastasized PDA cells in a
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17

Ma, Sen, Dejun Ji, Xiaolong Wang, Yuxin Yang, Yinghua Shi, and Yulin Chen. "Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats." Cells 12, no. 12 (2023): 1645. http://dx.doi.org/10.3390/cells12121645.

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Hair fiber growth is determined by the spatiotemporally controlled proliferation, differentiation, and apoptosis of hair matrix cells (HMCs) inside the hair follicle (HF); however, dermal papilla cells (DPCs), the cell population surrounded by HMCs, manipulate the above processes via intercellular crosstalk with HMCs. Therefore, exploring how the mutual commutations between the cells are molecularly achieved is vital to understanding the mechanisms underlying hair growth. Here, based on our previous successes in cultivating HMCs and DPCs from cashmere goats, we combined a series of techniques,
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18

Liu, Yike, Xuejian Liu, Are Osen, Yu Shao, Hao Hu, and Yingcai Zheng. "Least-squares reverse time migration using controlled-order multiple reflections." GEOPHYSICS 81, no. 5 (2016): S347—S357. http://dx.doi.org/10.1190/geo2015-0479.1.

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Reverse time migration (RTM) using multiples generates inherent crosstalk artifacts due to the interference among multiples of different orders. We have developed a method to remove such crosstalk. This approach first separates the recorded seismic data into primary reflections and multiples using the surface-related multiples elimination algorithm and then isolates the multiples into different orders. We can take any specified, say the [Formula: see text]th, order of multiples data as the incident wave and the next higher order multiples data, ([Formula: see text])th order, as the correspondi
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19

Peiffer, Raphaël, Yasmine Boumahd, Charlotte Gullo, et al. "Cancer-Associated Fibroblast Diversity Shapes Tumor Metabolism in Pancreatic Cancer." Cancers 15, no. 1 (2022): 61. http://dx.doi.org/10.3390/cancers15010061.

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Despite extensive research, the 5-year survival rate of pancreatic cancer (PDAC) patients remains at only 9%. Patients often show poor treatment response, due partly to a highly complex tumor microenvironment (TME). Cancer-associated fibroblast (CAF) heterogeneity is characteristic of the pancreatic TME, where several CAF subpopulations have been identified, such as myofibroblastic CAFs (myCAFs), inflammatory CAFs (iCAFs), and antigen presenting CAFs (apCAFs). In PDAC, cancer cells continuously adapt their metabolism (metabolic switch) to environmental changes in pH, oxygenation, and nutrient
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20

Shifteh, David, Tzuriel Sapir, Moshe Pahmer, Sanjay Goel, and Radhashree Maitra. "Abstract 534: PRMT5 inhibition as a therapeutic strategy for KRAS mutant CRC: downstream mediators of the PRMT5-KRAS crosstalk." Cancer Research 83, no. 7_Supplement (2023): 534. http://dx.doi.org/10.1158/1538-7445.am2023-534.

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Abstract Despite decades of research, there are still no effective targeted treatments for the nearly 45% of colorectal cancer (CRC) patients harboring a mutation in their KRAS gene. Protein Arginine Methyltransferase 5 (PRMT5) is an epigenetic regulator undergoing clinical trials as a potential therapeutic target for cancer. Our group has previously reported that PRMT5 is overexpressed in KRAS mutant CRC when compared to KRAS wild-type (WT) CRC, and that PRMT5 inhibition exhibited greater therapeutic efficacy in KRAS mutant CRC when compared to KRAS WT CRC. We therefore proposed that PRMT5 ma
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21

Aldhaibani, A. O., S. A. Aljunid, Hilal A. Fadhil, and M. S. Anuar. "Increasing Capacity and Suppress the Crosstalk by Using Hybrid Optical OFDM/WDM System." Key Engineering Materials 594-595 (December 2013): 1041–44. http://dx.doi.org/10.4028/www.scientific.net/kem.594-595.1041.

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Hybrid optical OFDM/WDM system is proposed to provide longer reach and larger capacity comparing with existing PON systems in order to meet the ever increasing bandwidth demand and data rate of next generation optical access networks. In this paper, two channels using different modulation at 10 Gb/s are used for downstream link. OFDM signals occupy different portions of the available signal spectrum for signal transmissions by using WDM. As a result, the system has good performance based on SNR with 50 km distance and QAM modulation delivers better performance compared with PSK.
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Peer, Elisabeth, Suzana Tesanovic, and Fritz Aberger. "Next-Generation Hedgehog/GLI Pathway Inhibitors for Cancer Therapy." Cancers 11, no. 4 (2019): 538. http://dx.doi.org/10.3390/cancers11040538.

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The Hedgehog/Glioma-associated oncogene homolog (HH/GLI) signaling pathway regulates self-renewal of rare and highly malignant cancer stem cells (CSC), which have been shown to account for the initiation and maintenance of tumor growth as well as for drug resistance, metastatic spread and relapse. Efficacious therapeutic approaches targeting CSC pathways, such as HH/GLI signaling in combination with chemo, radiation or immunotherapy are, therefore, of high medical need. Pharmacological inhibition of HH/GLI pathway activity represents a promising approach to eliminate malignant CSC. Clinically
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23

Yang, Hee Jo, Doo Sang Kim, Kwang Woo Lee, and Young Ho Kim. "The Urinary Microbiome; Axis Crosstalk and Short-Chain Fatty Acid." Diagnostics 12, no. 12 (2022): 3119. http://dx.doi.org/10.3390/diagnostics12123119.

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Our knowledge that “urine is sterile” is no longer accepted after the development of a next-generation sequencing (NGS) test. Using NGS, microbiota in the human body were discovered, and it is expected that this will improve our understanding of human diseases. However, the mechanism involved in the effect of the microbiome on diseases is still poorly understood. Associations of gut microbiome with diseases have been recently reported. Based on such associations, bladder–gut–brain axis, gut–bladder axis, gut–vagina–bladder axis, and gut–kidney axis as novel mechanisms of action of the microbio
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24

Chung, Carolina H., Da-Wei Lin, Alec Eames, and Sriram Chandrasekaran. "Next-Generation Genome-Scale Metabolic Modeling through Integration of Regulatory Mechanisms." Metabolites 11, no. 9 (2021): 606. http://dx.doi.org/10.3390/metabo11090606.

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Genome-scale metabolic models (GEMs) are powerful tools for understanding metabolism from a systems-level perspective. However, GEMs in their most basic form fail to account for cellular regulation. A diverse set of mechanisms regulate cellular metabolism, enabling organisms to respond to a wide range of conditions. This limitation of GEMs has prompted the development of new methods to integrate regulatory mechanisms, thereby enhancing the predictive capabilities and broadening the scope of GEMs. Here, we cover integrative models encompassing six types of regulatory mechanisms: transcriptional
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Chachalis, Demosthenis, Eleni Tani, Aliki Kapazoglou, et al. "Broomrapes in Major Mediterranean Crops: From Management Strategies to Novel Approaches for Next-Generation Control." BioTech 14, no. 2 (2025): 40. https://doi.org/10.3390/biotech14020040.

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Broomrapes (Orobanche and Phelipanche spp.) are parasitic weeds that significantly impact the productivity of major crops in the Mediterranean region, like tomato (Solanum spp.) and faba bean (Vicia faba) species. This review article extensively discusses management strategies to control broomrapes, which range from preventive measures to curative approaches. Additionally, it includes meaningful information on the intricate molecular mechanisms underlying the broomrape–host interaction, focusing on the host recognition of parasitic plant molecular patterns and the hormonal crosstalk that regul
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Buliga-Finis, Oana Nicoleta, Anca Ouatu, Minerva Codruta Badescu, et al. "Beyond the Cardiorenal Syndrome: Pathophysiological Approaches and Biomarkers for Renal and Cardiac Crosstalk." Diagnostics 12, no. 4 (2022): 773. http://dx.doi.org/10.3390/diagnostics12040773.

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Cardiorenal syndrome encompasses complex multifactorial facets and carries significant morbidity and mortality worldwide. The bi-directional relationship between the heart and kidneys, where dysfunction in one organ worsens the function of the other, has been the leading motor for research in the last few years. In the pathophysiological process, small noncoding RNAs, epigenetics, vascular growth factors, oxidative stress, hemodynamic factors, and biomarkers play a pivotal role in the development of cardiorenal syndrome. It is therefore important to elucidate all the mechanisms in order to pro
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27

Ross, Karen E., Guolin Zhang, Cuneyt Akcora, et al. "Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer." PLOS Computational Biology 19, no. 3 (2023): e1010690. http://dx.doi.org/10.1371/journal.pcbi.1010690.

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We analyzed large-scale post-translational modification (PTM) data to outline cell signaling pathways affected by tyrosine kinase inhibitors (TKIs) in ten lung cancer cell lines. Tyrosine phosphorylated, lysine ubiquitinated, and lysine acetylated proteins were concomitantly identified using sequential enrichment of post translational modification (SEPTM) proteomics. Machine learning was used to identify PTM clusters that represent functional modules that respond to TKIs. To model lung cancer signaling at the protein level, PTM clusters were used to create a co-cluster correlation network (CCC
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Singhal, Ankur, Amit Gupta, Surbhi Bakshi, Harbinder Singh, and Tarun Singhal. "Impact of higher‐order dispersion on crosstalk in hybrid OWC access systems for next‐generation communication networks." Microwave and Optical Technology Letters 64, no. 4 (2022): 655–59. http://dx.doi.org/10.1002/mop.33171.

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29

Murthy, Aditya, Yang Washington Shao, Juan Guinea-Viniegra, et al. "Epidermal ADAM17 provides barrier immunity and prevents myeloproliferative disease by regulating Notch-AP1 interaction (166.7)." Journal of Immunology 186, no. 1_Supplement (2011): 166.7. http://dx.doi.org/10.4049/jimmunol.186.supp.166.7.

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Abstract Epithelial cells are the major component of mucosal tissues such as the skin, gut and lungs. They are critical barriers against environmental stress factors which induce significant immunopathology. Keratinocytes in the skin may act as key decision-makers of immune cell function by directing local adaptive immune responses and hematopoietic development, however mechanisms driving epithelial:immune crosstalk are incompletely understood. The cell surface sheddase A Disintegrin and Metalloproteinase 17 (ADAM17) cleaves numerous proteins with key roles in development, stress response and
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Pancheva, Alexandrina, Helen Wheadon, Simon Rogers, and Thomas D. Otto. "Using topic modeling to detect cellular crosstalk in scRNA-seq." PLOS Computational Biology 18, no. 4 (2022): e1009975. http://dx.doi.org/10.1371/journal.pcbi.1009975.

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Cell-cell interactions are vital for numerous biological processes including development, differentiation, and response to inflammation. Currently, most methods for studying interactions on scRNA-seq level are based on curated databases of ligands and receptors. While those methods are useful, they are limited to our current biological knowledge. Recent advances in single cell protocols have allowed for physically interacting cells to be captured, and as such we have the potential to study interactions in a complimentary way without relying on prior knowledge. We introduce a new method based o
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Enguita, Francisco, Marina Costa, Ana Fusco-Almeida, Maria Mendes-Giannini, and Ana Leitão. "Transcriptomic Crosstalk between Fungal Invasive Pathogens and Their Host Cells: Opportunities and Challenges for Next-Generation Sequencing Methods." Journal of Fungi 2, no. 1 (2016): 7. http://dx.doi.org/10.3390/jof2010007.

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32

Enguita, Francisco, Marina Costa, Ana Fusco-Almeida, Maria Mendes-Giannini, and Ana Leitão. "Transcriptomic Crosstalk between Fungal Invasive Pathogens and Their Host Cells: Opportunities and Challenges for Next-Generation Sequencing Methods." Journal of Fungi 2, no. 1 (2016): 7. https://doi.org/10.5281/zenodo.13526022.

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33

Enguita, Francisco, Marina Costa, Ana Fusco-Almeida, Maria Mendes-Giannini, and Ana Leitão. "Transcriptomic Crosstalk between Fungal Invasive Pathogens and Their Host Cells: Opportunities and Challenges for Next-Generation Sequencing Methods." Journal of Fungi 2, no. 1 (2016): 7. https://doi.org/10.5281/zenodo.13526022.

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34

Enguita, Francisco, Marina Costa, Ana Fusco-Almeida, Maria Mendes-Giannini, and Ana Leitão. "Transcriptomic Crosstalk between Fungal Invasive Pathogens and Their Host Cells: Opportunities and Challenges for Next-Generation Sequencing Methods." Journal of Fungi 2, no. 1 (2016): 7. https://doi.org/10.5281/zenodo.13526022.

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35

Enguita, Francisco, Marina Costa, Ana Fusco-Almeida, Maria Mendes-Giannini, and Ana Leitão. "Transcriptomic Crosstalk between Fungal Invasive Pathogens and Their Host Cells: Opportunities and Challenges for Next-Generation Sequencing Methods." Journal of Fungi 2, no. 1 (2016): 7. https://doi.org/10.5281/zenodo.13526022.

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36

Rivera, Cristobal, Michele Silvestro, Muhammad Yogi Pratama, Steven Medvedovsky, and Bhama Ramkhelawon. "Crosstalk between Megakaryocyte Niches Unveils the Origin of Immunoreactive Platelets." Blood 142, Supplement 1 (2023): 679. http://dx.doi.org/10.1182/blood-2023-173055.

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Platelets play a prominent role in the pathophysiology of cardiovascular disease (CVD) however, the precise origin and function of pathological platelets remain elusive. While the bone marrow has been long established as a central site of platelet production, other important niches of platelet biogenesis have recently emerged. The role of platelets produced outside the bone marrow and the cross-communication between these niches remain incompletely understood. Here, we investigate the pathological role of lung-derived platelets in the development of immunothrombotic diseases. First, we show th
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Xu, Shuoyan, Zigan Xu, Ding Li, et al. "Recent Advances in Flexible Piezoresistive Arrays: Materials, Design, and Applications." Polymers 15, no. 12 (2023): 2699. http://dx.doi.org/10.3390/polym15122699.

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Spatial distribution perception has become an important trend for flexible pressure sensors, which endows wearable health devices, bionic robots, and human–machine interactive interfaces (HMI) with more precise tactile perception capabilities. Flexible pressure sensor arrays can monitor and extract abundant health information to assist in medical detection and diagnosis. Bionic robots and HMI with higher tactile perception abilities will maximize the freedom of human hands. Flexible arrays based on piezoresistive mechanisms have been extensively researched due to the high performance of pressu
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Gu, Moses, Suin Chae, Seonwoo Kim, et al. "High-Performance EMI Shielding Film Based on Low-Dk Polyimide and Trimodal Ag Ink for High-Speed Signal Integrity Enhancement." Micro 5, no. 2 (2025): 26. https://doi.org/10.3390/micro5020026.

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Electromagnetic interference (EMI) shielding is critical for maintaining signal integrity in high-speed electronic packaging. However, conventional shielding approaches face limitations in process complexity and spatial efficiency. In this study, an EMI shielding film based on trimodal silver (Ag) ink and low-dielectric polyimide (PI) resin was developed and comprehensively evaluated. The fabricated film exhibited an average shielding effectiveness (SE) of −99.7 dB in the 6–18 GHz frequency range and demonstrated a 50% increase in electrical conductivity after lamination (from 0.752 × 105 S/m
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Craddock, Vaughn D., Christine M. Cook, and Navneet K. Dhillon. "Exploring extracellular vesicles as mediators of clinical disease and vehicles for viral therapeutics: Insights from the COVID-19 pandemic." Extracellular Vesicles and Circulating Nucleic Acids 3, no. 3 (2022): 172–88. http://dx.doi.org/10.20517/evcna.2022.19.

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The COVID-19 pandemic has challenged researchers to rapidly understand the capabilities of the SARS-CoV-2 virus and investigate potential therapeutics for SARS-CoV-2 infection. COVID-19 has been associated with devastating lung and cardiac injury, profound inflammation, and a heightened coagulopathic state, which may, in part, be driven by cellular crosstalk facilitated by extracellular vesicles (EVs). In recent years, EVs have emerged as important biomarkers of disease, and while extracellular vesicles may contribute to the spread of COVID-19 infection from one cell to the next, they also may
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Borodinov, Andrew, Vladimir Manoilov, Igor Zarutsky, Alexander Petrov, Vladimir Kurochkin, and Aleksey Saraev. "Machine Learning in Base-Calling for Next-Generation Sequencing Methods." Informatics and Automation 21, no. 3 (2022): 572–603. http://dx.doi.org/10.15622/ia.21.3.5.

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The development of next-generation sequencing (NGS) technologies has made a significant contribution to the trend of reducing costs and obtaining massive sequencing data. The Institute for Analytical Instrumentation of the Russian Academy of Sciences is developing a hardware-software complex for deciphering nucleic acid sequences by the method of mass parallel sequencing (Nanofor SPS). Image processing algorithms play an essential role in solving the problems of genome deciphering. The final part of this preliminary analysis of raw data is the base-calling process. Base-calling is the process
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Hur, Y., Moonkyun Maeng, C. Chun, et al. "Equalization and near-end crosstalk (NEXT) noise cancellation for 20-Gb/s 4-PAM backplane serial I/O interconnections." IEEE Transactions on Microwave Theory and Techniques 53, no. 1 (2005): 246–55. http://dx.doi.org/10.1109/tmtt.2004.839311.

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Mishra, Jitendra K., B. M. A. Rahman, and Vishnu Priye. "Rectangular Array Multicore Fiber Realizing Low Crosstalk Suitable for Next-Generation Short-Reach Optical Interconnects With Low Misalignment Loss." IEEE Photonics Journal 8, no. 4 (2016): 1–14. http://dx.doi.org/10.1109/jphot.2016.2591002.

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43

Bauminger, Hagar, and Inna Gaisler-Salomon. "Beyond NMDA Receptors: Homeostasis at the Glutamate Tripartite Synapse and Its Contributions to Cognitive Dysfunction in Schizophrenia." International Journal of Molecular Sciences 23, no. 15 (2022): 8617. http://dx.doi.org/10.3390/ijms23158617.

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Cognitive deficits are core symptoms of schizophrenia but remain poorly addressed by dopamine-based antipsychotic medications. Glutamate abnormalities are implicated in schizophrenia-related cognitive deficits. While the role of the NMDA receptor has been extensively studied, less attention was given to other components that control glutamate homeostasis. Glutamate dynamics at the tripartite synapse include presynaptic and postsynaptic components and are tightly regulated by neuron–astrocyte crosstalk. Here, we delineate the role of glutamate homeostasis at the tripartite synapse in schizophre
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Tan, Mengtian, Lai Jiang, Yinglei Li, and Wei Jiang. "Dual Inhibition of BMP and WNT Signals Promotes Pancreatic Differentiation from Human Pluripotent Stem Cells." Stem Cells International 2019 (December 1, 2019): 1–15. http://dx.doi.org/10.1155/2019/5026793.

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Pathological or functional loss of pancreatic beta cells is the cause of diabetes. Understanding how signaling pathways regulate pancreatic lineage and searching for combinations of signal modulators to promote pancreatic differentiation will definitely facilitate the robust generation of functional beta cells for curing hyperglycemia. In this study, we first tested the effect of several potent BMP inhibitors on pancreatic differentiation using human embryonic stem cells. Next, we examined the endodermal lineage bias upon potent BMP inhibitor treatment and further checked the crosstalk between
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Ennishi, Daisuke, Fong Chun Chan, David W. Scott, et al. "Genetic Alterations In Immune Cell Crosstalk Genes In Diffuse Large B-Cell Lymphoma Predict Survival." Blood 122, no. 21 (2013): 500. http://dx.doi.org/10.1182/blood.v122.21.500.500.

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Abstract Background Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype accounting for ∼40% of all non-Hodgkin lymphomas. Although R-CHOP has significantly improved outcome in DLBCL, 35% of patients still experience relapsed/refractory disease. Further investigation into the genomic architecture of DLBCL is needed to determine the biological correlates that underlie treatment failure. Immune cell signatures have been shown to impact survival in DLBCL (Lenz et al, NEJM 2008). Recurrent mutations and/or copy number alterations (CNAs) in genes that impact the tumor's immune-
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Grozovsky, Renata, Cameron Fraser, Karin M. Hoffmeister, Kristopher Sarosiek, and Silvia Giannini. "Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance." Blood 134, Supplement_1 (2019): 1055. http://dx.doi.org/10.1182/blood-2019-122184.

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Our understanding of cell biological processes involved in aging has advance greatly over the past decades. Platelets are small cells that circulate for 4-5 days in mice and 7-10 days in humans. And even though, platelets are anucleated cells, a growing body of evidence shows that platelet clearance is a well-regulated mechanism. We have recently demonstrated that platelets lose sialic acid as they circulate and age in blood and are rapidly cleared by the hepatic Ashwell-Morell receptor (AMR). And others have shown, in a series of studies using genetically modified mice or pharmacological inhi
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YUE, C. PATRICK, JAEJIN PARK, RUIFENG SUN, L. RICK CARLEY, and FRANK O'MAHONY. "LOW-POWER, PARALLEL INTERFACE WITH CONTINUOUS-TIME ADAPTIVE PASSIVE EQUALIZER AND CROSSTALK CANCELLATION." International Journal of High Speed Electronics and Systems 15, no. 02 (2005): 459–76. http://dx.doi.org/10.1142/s0129156405003260.

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This paper presents the low-power circuit techniques suitable for high-speed digital parallel interfaces each operating at over 10 Gbps. One potential application for such high-performance I/Os is the interface between the channel IC and the magnetic read head in future compact hard disk systems. First, a crosstalk cancellation technique using a novel data encoding scheme is introduced to suppress electromagnetic interference (EMI) generated by the adjacent parallel I/Os . This technique is implemented utilizing a novel 8-4-PAM signaling with a data look-ahead algorithm. The key circuit compon
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Smaga, Irena. "Understanding the Links among Maternal Diet, Myelination, and Depression: Preclinical and Clinical Overview." Cells 11, no. 3 (2022): 540. http://dx.doi.org/10.3390/cells11030540.

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Depression is one of the most common mental disorders in the general population, and multiple mechanisms are involved in the etiology of this disease, including myelination. According to the Developmental Origins of Health and Disease (DOHaD) hypothesis, maternal diet affects the lifetime of the individual during adulthood and may contribute to the development of neuropsychiatric disorders. Additionally, the intensive processes of myelination contribute to the development of the central nervous system in the perinatal period, while any alterations during this crucial process providing the phys
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Lee, Sangbin, Jaehyun Hong, Joonho Kang, et al. "Inverse design of color routers in CMOS image sensors: toward minimizing interpixel crosstalk." Nanophotonics, July 1, 2024. http://dx.doi.org/10.1515/nanoph-2024-0269.

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Abstract Over the past decade, significant advancements in high-resolution imaging technology have been driven by the miniaturization of pixels within image sensors. However, this reduction in pixel size to submicrometer dimensions has led to decreased efficiency in color filters and microlens arrays. The development of color routers that operate at visible wavelengths presents a promising avenue for further miniaturization. Despite this, existing color routers often encounter severe interpixel crosstalk, around 70 %, due to the reliance on periodic boundary conditions. Here, we present interp
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Ponchua, Jirasak, and Suchada Sitjongsataporn. "Design of Four-Core Uncoupled Multicore Fiber for Next-Generation Inter-Data Center Networks." Journal of Mobile Multimedia, November 16, 2021. http://dx.doi.org/10.13052/jmm1550-4646.1821.

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The increasing demands within and between the data centers used for data traffic has required. Efficient links are important to data center applications for supporting the unlimited demand. Transmission capacity of single-mode fiber (SMF) is limited by fiber nonlinearity which prevents the increasing transmission power and finite amplifier bandwidth. Single-mode multi-core fibers (SM-MCFs) that are expected to overcome the current limitation of optical communication capacity. However, the inter-core crosstalk still has an effect on SM-MCF, which can limit the transmission of the inter-data cen
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