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1

Kusner, David John. "Regulation of phospholipase D activity in U937 cells." Case Western Reserve University School of Graduate Studies / OhioLINK, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=case1057945948.

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2

Torrie, Joan P. "Extracellular beta-D-mannanase activity from Trichoderma harzianum E58." Thesis, University of Ottawa (Canada), 1991. http://hdl.handle.net/10393/7732.

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In this work, 4 yeasts (Pichia wickerhammi, Candida wickerhammi, Pichia stipitis CBS5776, Pichia stipitis CBS5876), and 5 fungi (Theivalia spp., Thermoascus aurantiacus, Tyromyces palustris A, Aspergillus niger, Trichoderma harzianum), known to excrete enzymes capable of hydrolyzing polysaccharides found in association with $\beta$-D-mannans, were assessed for their ability to degrade $\beta$-D-mannans. The $\beta$-D-mannanase activity found in the culture filtrate of T. harzianum was selected for further study and a 'cellulase-free' $\beta$-D-mannanase isolated from culture filtrates of T. ha
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3

Raymond, Frank Damian. "Inositol specific phospholipase D activity : a GPI-cleaving enzyme." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321569.

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4

Jathoul, Amit Paul. "Activity of firefly luciferase with 6'-amino-D-luciferin." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612384.

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5

Blanke, Ulf Mario [Verfasser]. "Recognizing Complex Human Activity Based on Activity Spotting / Ulf Mario Blanke." München : Verlag Dr. Hut, 2011. http://d-nb.info/1017353484/34.

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6

Pham, Ethan. "Relationships among Vitamin D Deficiency, Metabolic Syndrome, Smoking Behavior, and Physical Activity." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/4812.

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Aging increases the risk of both vitamin D deficiency and metabolic syndrome. Vitamin D deficiency and metabolic syndrome may be related, although there are mixed findings. Furthermore, literature suggests other factors such as physical fitness activity and smoking behavior are associated with Vitamin D deficiency and the development of metabolic syndrome. A number of studies have documented associations between Vitamin D levels and physical fitness activities, while other studies found correlations between Vitamin D levels, metabolic syndrome, and smoking behavior. However, no previous study
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7

Suzana, Jovanović-Šanta. "Biološka aktivnost novosintetisanih D-seko i D-homo-estratrienskih derivata u in vivo i in vitro uslovima." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2010. http://dx.doi.org/10.2298/NS20101008JOVANOVICSANTA.

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Sintetisana su nova jedinjenja, 16- i 17-supstituisani&nbsp;16,17-sekoestratrienski derivati i D-homoestranski&nbsp;derivati, polazeći od 3-benziloksi-17-hidroksi-16,17-sekoestra-1,3,5(10)-trien-16-nitrila. Ispitana je&nbsp;estrogena i antiestrogena aktivnost u eksperimentima <em>in&nbsp;vivo</em>, antiaromatazna aktivnost <em>in vitro</em>, antioksidantna&nbsp;aktivnost DPPH &nbsp;i TBA testom, kao i antiproliferativna&nbsp;aktivnost prema ćelijskim linijama MCF-7 ATCC,&nbsp;MDA-MB-231, HT-29 i MRC-5 novosintetisanih&nbsp;jedinjenja.<br>Some new compounds, 16- and 17-substituted 16,17-secoest
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8

Fantino, Davide. "Innovation activity, R&D incentives, competition and market value." Thesis, London School of Economics and Political Science (University of London), 2010. http://etheses.lse.ac.uk/166/.

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This thesis examines some characteristics of the interaction between innovation activity of firms, in particular R&D, and economic system. The first main chapter analyses a mechanism of interaction between R&D and market structure, in a horizontally differentiated market where firms invest to increase differentiation among varieties. R&D activity declines over time; prices, output and short-run profits of firms producing the differentiated product move towards the higher steadystate values, production of the non-differentiated good falls. The increasing specialization improves the overall util
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9

Gupta-Ostermann, Disha [Verfasser]. "Computational Methods for Structure-Activity Relationship Analysis and Activity Prediction / Disha Gupta-Ostermann." Bonn : Universitäts- und Landesbibliothek Bonn, 2015. http://d-nb.info/1080561277/34.

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10

Scammells, Peter J., and n/a. "Pyrazolo(3,4-d)Pyrimidines and adenosine receptors: a structure/activity study." Griffith University. Division of Science and Technology, 1990. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20050826.141630.

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Pyrazolopyrimidines are a general class of compounds which exhibit Aj adenosine receptor affmity. A number of pyrazolo(3,4-d)pyrimidine analogues of isoguanosine and i-methylisoguanosine has been synthesised. All compounds were tested forAi adenosine receptor affinity using a (311) R-PIA competitive binding assay. The N-i and N-5 positions were substituted with a number of different ailcyl and aryi groups. 3-Chiorophenyl substitution of the N-i position and butyl substitution of the N-5 position greatly enhanced the overall adenosine receptor affinity. Substitution by a methyl group at the N-7
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11

Devlin, Marni Allison. "The characterization of TSH-mediated phospholipase D activity in thyroid cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0017/MQ47020.pdf.

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12

Curtis, Ffion. "The role of Vitamin D and physical activity in glycaemic homeostasis." Thesis, Aberystwyth University, 2015. http://hdl.handle.net/2160/273bb25b-0cdf-4dfb-93fa-c7e0e89b3434.

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In Wales nearly 5% (160,000) of the population have been diagnosed with diabetes, and it is thought that there is another 66,000 undiagnosed cases (Diabetes UK). Vitamin D deficiency is also increasing in prevalence, and there is emerging evidence linking vitamin D deficiency to impaired β-cell function, insulin resistance, and glucose intolerance, all of which are central to the pathogenesis of type 2 diabetes (Song & Manson, 2010). Following NHS and University ethical approval Welsh domiciled participants (n = 116) with varying levels of glucose control attended the Department of Sport and E
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13

Dessyllas, Panayotis J. "Mergers, R&D and patenting activity in high technology sectors." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614788.

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14

Loedolff, Michiel Christiaan. "Synthesis and structure-activity relationships of ring D alkyl 19-norsteroids." Doctoral thesis, University of Cape Town, 1996. http://hdl.handle.net/11427/18380.

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Studies have been conducted in synthesising ring D alkyl 19- norsteroids. The aim was to investigate methods for the stereoselective introduction of alkyl groups at C(14) and C(15), for eventual conversion of the intermediates into 14- and 15-alkyl analogues of estradiol hormones. In the first phase of this investigation, 17β-tert-butyldimethylsilyloxyestra-1,3,5(10),14-tetraen-l6-one was synthesised as starting material for alkylation experiments. Estrone 3-methyl ether was converted into the derived 17β-hydroxy 16-ketone by standard methods. This conversion involved the introduction of a 16α
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15

Jardine, Mogamad Anwar. "Synthesis and structure activity relationships of ring D modified steroidal hormones." Doctoral thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/17900.

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Includes bibliographical references.<br>The synthesis of steroidal 14α,16-methano, 14α,17-methano-, 14α,17-ethano- and 14α,17-propano estradiol analogues as well as 14α-alkyl and 14α-functionalised-alkyl estradiol analogues was investigated. Furthermore, the synthesis of 17β-hydroxy-17α, 14-(epoxymethano)androst-4-en-3-one was undertaken and acid-mediated rearrangement of the 14,17-etheno bridged testosterone analogue gave the 14,16-ethano analogue of androst-4-en-3,17-dione. Established ring D cycloaddition and oxidative cleavage methodology gave ring D 14α-formyl and 14α, 17α-diformyl compou
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16

Scammells, Peter. "Pyrazolo(3,4-d)Pyrimidines and adenosine receptors: a structure/activity study." Thesis, Griffith University, 1990. http://hdl.handle.net/10072/365214.

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Pyrazolopyrimidines are a general class of compounds which exhibit Aj adenosine receptor affmity. A number of pyrazolo(3,4-d)pyrimidine analogues of isoguanosine and i-methylisoguanosine has been synthesised. All compounds were tested forAi adenosine receptor affinity using a (311) R-PIA competitive binding assay. The N-i and N-5 positions were substituted with a number of different ailcyl and aryi groups. 3-Chiorophenyl substitution of the N-i position and butyl substitution of the N-5 position greatly enhanced the overall adenosine receptor affinity. Substitution by a methyl group at the N-7
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17

Marianelli, Stefano. "In Vitro Activity Characterization of Novels Pyrazolo[3,4-d]Pyrimidine Prodrugs." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1202148.

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The first part of this thesis focuses on the set-up of a bio-analytical and synthesis laboratory in line with ISO and GLP-Like requirements. Research projects carried out in the academic world while valid from a scientific point of view, are characterized by a poor level of accuracy and robustness due to the absence of a fine procedural and operational control. This defect inevitably compromises the quality of the data obtained, making the entire scientific project less attractive for investors such as pharmaceutical companies. Good Laboratory Practices (GLP) as well as ISO standards deal with
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18

Lennefer, Thomas [Verfasser]. "Activity Trackers Work / Thomas Lennefer." Berlin : Humboldt-Universität zu Berlin, 2021. http://d-nb.info/1226153313/34.

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19

P, Savić Marina. "Sinteza i antiproliferativna aktivnost novih D-homo i D-seko derivata androstana." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2013. http://dx.doi.org/10.2298/NS20130319SAVIC.

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U prvom delu ove doktorske disertacije je izvr&scaron;enasinteza novih derivata androstana sa D-laktonskomfunkcijom ili D-seko derivata, sa modifikacijama u Ai/ili B-prstenovima. U drugom delu je ispitanaantiproliferativna aktivnost odabranihnovosintetizovanih jedinjenja prema humanimtumorskim ćelijskim linijama (MCF-7, MDA-MB-231,PC-3, HeLa, HT-29, K562) kao i prema zdravimćelijama fetalnih fibroblasta pluća (MRC-5).<br>In first part of this work was achieved synthesis of&nbsp;some new androstane derivatives with D-lactone&nbsp;function and new D-seco derivatives with modification&nbsp;in A a
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20

Naude, Dollien. "Liggaamsamestelling, groeivertraging en fisieke aktiwiteit van swart adolessente in 'n dorpsgemeenskap : PLAY studie / D. Naude." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4982.

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In South Africa a remarkable weight gain is found in black adolescent girls during mid-adolescence, which is not necessarily the case among boys (Kalk, 2001:577) . Anthropometry is one of the most basic methods for determining over-nutrition and malnutrition status. A considerable amount of research is indeed done on obesity, and quite an amount on growth stunting (OS), but few interventions exist for prevention and treatment of OS. The World Health Organization (WHO) has determined that approximately 230 million children world wide are growth stunted (OS) (WHO working group, 1986). Physical a
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21

Poisot, Vazquez Martha Emilia [Verfasser]. "Studies to develop high activity MoS2 : crystallography, thermal analysis and catalytic activity / Martha Emilia Poisot Vazquez." Kiel : Universitätsbibliothek Kiel, 2008. http://d-nb.info/1019613386/34.

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22

Gräfenhain, Maria. "Young children's understanding of joint activity." Leipzig Leipziger Univ.-Verl, 2008. http://d-nb.info/998767239/04.

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23

Kotecha, Suhas Ashok. "G-protein coupled receptor modulation of N-methyl-D-aspartate channel activity." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ63766.pdf.

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24

Arktedius, Andreas, and Viktor Preiman. "IPO Underpricing and R&D Activity : Evidence from the Swedish Market." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447054.

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Historical research on initial public offerings (IPOs) presents strong evidence of underpricing. This study investigates if there is a relationship between underpricing of IPOs and pre-IPO research and development (R&amp;D) activities within a company. According to the literature, R&amp;D activities have characteristics of information asymmetry and uncertainty, which can increase underpricing. This study’s sample consists of 231 Swedish companies listed on Nasdaq Stockholm and Nasdaq First North between January 2010 and December 2020. Sweden has a strong association with innovation activities
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25

Kenny, Niall Anthony P. "Locomotor activity rhythms and photoperiodic time-measurement in the blowfly Calliphora vicina R-D." Thesis, University of Edinburgh, 1989. http://hdl.handle.net/1842/12352.

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26

Alves, Teixeira Maraiza. "Cholecalciferol (vitamin D3) has a direct protective activity in C2C12 myotubes." Doctoral thesis, Università del Piemonte Orientale, 2021. http://hdl.handle.net/11579/127832.

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Skeletal muscle depletion occurs, among other conditions, in oncologic patients. Cancer cachexia is a multicomponent syndrome which physiopathology involves metabolic alterations, like hormonal imbalance. One of the hormones that are dysregulated in cancer cachexia is Vitamin D (VD). Besides its important role in bone mineralization, regulating calcium and phosphate homeostasis, VD affects skeletal muscle. In fact, VD deficiency has been associated with a wide range of muscle disorders, such as a decrease in muscle mass and functionality. Even though VD deficiency is highly prevalent among adv
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27

Scholl, Philipp Marcel [Verfasser], Kristof Van [Akademischer Betreuer] Laerhoven, and Bernd [Akademischer Betreuer] Becker. "Activity recognition with instrumented and wearable artifacts." Freiburg : Universität, 2018. http://d-nb.info/1155722396/34.

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28

Tazkari, Reza [Verfasser]. "Physical activity, aging and cognition / Reza Tazkari." Bielefeld : Universitätsbibliothek Bielefeld, 2016. http://d-nb.info/1084885328/34.

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29

Böhme, Martin [Verfasser]. "Tracking gaze and human activity / Martin Böhme." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2010. http://d-nb.info/1004772181/34.

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30

Högström, Magnus. "Vitamins, fatty acids, physical activity and peak bone mass /." Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1451.

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31

Psakis, Georgios. "The D-galactose-H⁺ symporter (GaIP) from Escherichia coli : structure-activity relationship." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414216.

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32

Peery, Sven L. "Catalase Activity Mediates the Inhibitory Actions of 24,25 Dihydroxyvitamin D3." DigitalCommons@USU, 2006. https://digitalcommons.usu.edu/etd/5535.

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The steroid hormone 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] rapidly stimulates the uptake of phosphate in isolated chick intestinal cells , while the steroid 24,25- dihydroxyvitamin D3 [24,25(OH)2D3] inhibits the rapid stimulation by l,25(OH)2D3. Earlier work in this laboratory has indicated that a cellular binding protein for the 24,25(OH)2D3 is the enzyme catalase. Since binding resulted in decreased catalase activity and increased H2O2 production, studies were undertaken to determine if pro-oxidant conditions mimicked the inhibitory actions of 24,25(OH)2D3, and anti-oxidant conditions preven
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33

Högström, Magnus. "Vitamins, fatty acids, physical activity and peak bone mass." Doctoral thesis, Umeå universitet, Kirurgisk och perioperativ vetenskap, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1451.

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Osteoporosis is a disease characterized by low bone mineral density, deteriorated bone microstructure and increased fracture risk. About 50% of all women and 25% of all men will have an osteoporotic fracture. Given that there is no effective cure in established osteoporosis, prevention is of high importance. Bone mineral density (BMD) is accumulated during childhood and adolescence with a peak at about 20 years of age. Peak BMD has been suggested to explain at least half of the variation in BMD up to old age. Thus, to increase peak BMD could decrease the risk of later fractures. The purpose of
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34

Gardell, Pierre. "R&D Activity Investments and Macroeconomic Determinant Factors : A Firm-level Investigation of Two Segments of the Electronic Industry in Sweden." Thesis, Södertörns högskola, Institutionen för samhällsvetenskaper, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-19610.

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Investments in R&amp;D activities are essential to firms. Decisions to increase or decrease R&amp;D investments may rely according to changes in macroeconomic factors. The purpose of this paper is: to examine how firms in the industries; manufacturing computers, electronics and optics and manufacturing electrical equipment, have increased or decreased their R&amp;D investments, in conjunction with macro factors during the 2000s. The sample is 49 Swedish firms. This paper is based on quantitative firm-level panel data on R&amp;D activity investments and aggregated quantitative macro-level data
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35

Blanco, Rodríguez Julián. "Magnetic activity at the poles of the sun." [Katlenburg-Lindau] Copernicus Publ, 2008. http://d-nb.info/988508125/04.

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36

Kiefer, René [Verfasser], and Markus [Akademischer Betreuer] Roth. "Seismic investigations of solar and stellar magnetic activity." Freiburg : Universität, 2018. http://d-nb.info/1160875421/34.

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37

Hauser, Jörn H. "Business-activity-Monitoring : ein Konzept zur Echtzeit-Prozessüberwachung /." Saarbrücken : VDM Verlag Dr. Müller, 2007. http://d-nb.info/986631450/04.

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38

Monfardini, Júlia Dietsche [UNESP]. "Diterpenos tetranorlabdanos e isocumarinas produzidos por Botryosphaeria parva, um fungo endofítico em Eugenia jambolana Lam. (Myrtaceae)." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/137771.

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Submitted by JULIA DIETSCHE MONFARDINI null (juliadm@iq.unesp.br) on 2016-04-01T16:52:10Z No. of bitstreams: 1 Dissertação_Julia Dietsche Monfardini.pdf: 10246419 bytes, checksum: dff6716d7f1e0f36c408ba7afeff1e25 (MD5)<br>Approved for entry into archive by Ana Paula Grisoto (grisotoana@reitoria.unesp.br) on 2016-04-05T18:12:36Z (GMT) No. of bitstreams: 1 monfardini_jd_me_araiq_par.pdf: 807325 bytes, checksum: 9a9635608b6709f23a60f0fd6f5e676e (MD5)<br>Made available in DSpace on 2016-04-05T18:12:36Z (GMT). No. of bitstreams: 1 monfardini_jd_me_araiq_par.pdf: 807325 bytes, checksum: 9a96356
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Poulsen, Sally-Ann, and n/a. "Pyrazolo(3,4-d)pyrimidines: Synthesis and Structure-Activity Relationships for Binding to Adenosine Receptors." Griffith University. School of Science, 1996. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20050901.161632.

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Chapter 1 of thesis is a literature review of adenosine research. The central importance of the contributions of both classical pharmacology and, more recently, molecular biology to adenosine research is demonstrated. These disciplines have enabled the classification and characterisation of adenosine receptors and as well an understanding of the physiological significance of endogenous adenosine. The significant benefits of developing therapeutics for regulation of the diverse physiological functions of adenosine, by regulation of adenosine receptors, is outlined. For this therapeutic potentia
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40

Meenaghan, Michael. "Human erythrocyte membrane UDPgal:GalNAc #beta#1,3 D-galactosyltransferase activity in individuals with Tn syndrome." Thesis, University of the West of England, Bristol, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236252.

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41

Poulsen, Sally-Ann. "Pyrazolo(3,4-d)pyrimidines: Synthesis and Structure-Activity Relationships for Binding to Adenosine Receptors." Thesis, Griffith University, 1996. http://hdl.handle.net/10072/365893.

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Chapter 1 of thesis is a literature review of adenosine research. The central importance of the contributions of both classical pharmacology and, more recently, molecular biology to adenosine research is demonstrated. These disciplines have enabled the classification and characterisation of adenosine receptors and as well an understanding of the physiological significance of endogenous adenosine. The significant benefits of developing therapeutics for regulation of the diverse physiological functions of adenosine, by regulation of adenosine receptors, is outlined. For this therapeutic potentia
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42

Wientzek-Fleischmann, Angelika [Verfasser], Heiner [Akademischer Betreuer] Boeing, and Reinhard [Akademischer Betreuer] Busse. "Physical activity and chronic disease risk : development and evaluation of a physical activity index and baseline physical activity data calibration in EPIC Germany / Angelika Wientzek-Fleischmann. Gutachter: Heiner Boeing ; Reinhard Busse. Betreuer: Heiner Boeing." Berlin : Technische Universität Berlin, 2014. http://d-nb.info/1067385959/34.

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43

Grieger, Jens [Verfasser]. "Cyclonic Activity and its Influences on Antarctica / Jens Grieger." Berlin : Freie Universität Berlin, 2015. http://d-nb.info/1077007248/34.

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44

Krause, Stefan [Verfasser]. "Effects of microbial activity on marine carbonates / Stefan Krause." Kiel : Universitätsbibliothek Kiel, 2012. http://d-nb.info/102687727X/34.

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45

Merkt, Benjamin [Verfasser], and Stefan [Akademischer Betreuer] Rotter. "On the measurement and analysis of neuronal subpopulation activity." Freiburg : Universität, 2019. http://d-nb.info/1187658553/34.

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46

Buck, Sebastian [Verfasser]. "Modeling Robotic Systems with Activity Flow Graphs / Sebastian Buck." München : Verlag Dr. Hut, 2018. http://d-nb.info/1164293788/34.

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47

Martinovic, Jasna. "Event related gamma-band activity in visual object representation." Leipzig Leipziger Univ.-Verl, 2007. http://d-nb.info/997541539/04.

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48

Roye, Björn van [Verfasser]. "Financial stress, uncertainty, and economic activity / Björn van Roye." Kiel : Universitätsbibliothek Kiel, 2013. http://d-nb.info/1042185573/34.

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49

Trescher, Saskia [Verfasser]. "Estimating Gene Regulatory Activity using Mathematical Optimization / Saskia Trescher." Berlin : Humboldt-Universität zu Berlin, 2020. http://d-nb.info/1218529822/34.

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Schauer, Christian Lothar [Verfasser], and Trese [Akademischer Betreuer] Leinders-Zufall. "GnRH-induced calcium signals and spike activity in GnRHR neurons : Change in activity during reproductive cycle? / Christian Lothar Schauer. Betreuer: Trese Leinders-Zufall." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2016. http://d-nb.info/1097263355/34.

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