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Dissertationen zum Thema „Diagnostics methods“

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1

Leitao, Maria Teresa Catarino. "Simulation-based methods for time series diagnostics." Thesis, London School of Economics and Political Science (University of London), 2004. http://etheses.lse.ac.uk/2299/.

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We present sampling-based methodologies for the estimation of structural time series in the presence of outliers and structural shifts. We start by considering a simple structural model: a local level model, in the presence of outliers and level shifts. The existence of shocks is accounted for by including a product of intervention variables in the measurement and transition equations. These factors are composed of the product of an indicator variable and a parameter for the magnitude of the intervention variable, defining the size of the shocks. The Gibbs sampler is the Markov chain Monte Car
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Al-Jaf, Bryar Salar Kamal. "Development of improved methods for phytoplasma diagnostics." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43654/.

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Phytoplasmas are plant pathogens that are small prokaryotic, wall-less bacteria causing significant diseases in hundreds of plant species globally. They have been named as distinct ‘Candidatus phytoplasma’ species and belong to the Mollicutes. These microorganisms are non-cultivable plant pathogens (obligate), so their diagnoses are primarily achieved by molecular techniques. In infected plants, they inhabit phloem tissues (sieve cells) and they are transmitted between plants by insects (phloem feeders) such as those in the orders Cicadellidae, Psyllidae and Fulgoridae. Phytoplasmas have extre
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Bazaras, Vilius. "Lėtaeigių riedėjimo guolių diagnostiniai tyrimai." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20130218_131748-24042.

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Baigiamajame darbe pateikta literatūros šaltinių apžvalga susijusi su riedėjimo guolių defektų diagnostika. Darbe sukurta lėtaeigių riedėjimo guolių (iki 380 aps/min) esančių „INVERFORM“ džiovyklinių mašinų grupėse tyrimų metodika bei atlikti eksperimentiniai tyrimai. Pagrindinis šių tyrimų tikslas – sukurti patikimą tyrimų metodą, skirtą eksploatuojamų lėtaeigių sferinių riedėjimo guolių defektams diagnozuoti ir techninei būklei įvertinti. Metodas buvo sukurtas išsamių guolių korpusų virpesių matavimų ir virpesių duomenų formatų analizės pagrindu, mašinai dirbant natūralios eksploatacijos sąl
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Jalali, Khooshahr Adrin [Verfasser]. "Interpretable methods in cancer diagnostics / Adrin Jalali Khooshahr." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2020. http://d-nb.info/1240674090/34.

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5

Hirvasniemi, J. (Jukka). "Novel X-ray-based methods for diagnostics of osteoarthritis." Doctoral thesis, Oulun yliopisto, 2015. http://urn.fi/urn:isbn:9789526210384.

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Abstract Osteoarthritis (OA) is the commonest joint disease in the world, and it has a major socioeconomic impact. OA causes progressive degenerative changes in the composition and structure of articular cartilage and subchondral bone. Clinical diagnosis of OA is based on physical examination and qualitative evaluation of changes on plain radiographs. Current clinical imaging methods are subjective or insensitive to early OA changes. Therefore, new methods are needed so as to quantify composition of the cartilage and characteristics of the subchondral bone. The aim of this thesis was to evalua
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Spooner, Andrew. "Multivariate analysis methods for veterinary diagnostics using SIFT-MS." Thesis, Cranfield University, 2010. http://dspace.lib.cranfield.ac.uk/handle/1826/5702.

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Selected ion flow tube mass spectroscopy (SIFT-MS) is an analytical method for the investigation of volatile organic compounds (VOCs). It produces mass to charge (m/z) ratio ion counts with a range of 10-200 m/z. Current data analysis involves sifting through the spectra files one at a time looking for peaks of interest. This is time consuming and requires expert knowledge. This thesis proposes, implements and demonstrates a novel approach to the analysis of SIFT-MS data using multivariate techniques similar to those employed to analyse electronic nose and gas chromatography mass spectroscopy
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Doria, Maria Luísa. "Development of spatially-resolved lipidomic methods for cancer diagnostics." Thesis, Imperial College London, 2017. http://hdl.handle.net/10044/1/58100.

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Ovarian cancer is the fifth most common cancer among women, with a great demand for the development of diagnostics towards improved performance, shorter turnaround time and lower costs. Lipids represent an important class of biomolecules with a unique but nevertheless poorly understood role in cancer pathophysiology. DESI-MSI (Desorption electrospray ionization mass spectrometric imaging) is an emerging mass spectrometric technique with great potential in cancer diagnostics and prognostics, giving spatially resolved profiling information. These techniques provide information on the metabolic a
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Dawson, Amy. "Paper microfluidics for clinical diagnostics using colourimetric detection methods." Thesis, University of Hull, 2014. http://hydra.hull.ac.uk/resources/hull:10515.

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Microfluidics is a technology currently aiming to advance the medical devices currently available in the developing and developed world through simultaneously creating point-of-care devices which are “as good” or better than current methods at a cheaper production cost. To be able to diagnose diseases and infections quickly and affordably remains the aim of many researchers and the use microfluidics has advantages which plug this difficulty. However, one main gap in the research is to train users for these devices which give accurate results when compared to current methods. Described herein a
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Retana, Hernández Roberto Carlos. "Diagnostics methods for armature faults in fractional horsepower commutator motors /." München : Verl. Dr. Hut, 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018707871&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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10

Veksler, Boris. "Low coherence optical methods for express noninvasive bio-medical diagnostics." Thesis, Cranfield University, 2010. http://dspace.lib.cranfield.ac.uk/handle/1826/4500.

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Coherence is the fundamental property of optical radiation. Methods based on this characteristic are employed in different areas of research even in NASA and European space agency. However, coherence properties of light can be successfully applied in life sciences for the purposes of diagnostics and treatment. The subject of current research is the development and improvement of the quantitative performance of non-invasive low coherence optical diagnostic which is a novel modern biomedical technique uniquely suited for the measurements of particles distribution within the topical layers of bio
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Terchi, Abdelaziz. "Wavelets and kernel based methods and acoustic emission signal diagnostics." Thesis, Brunel University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427664.

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Al-Taweel, Younus. "Diagnostics and simulation-based methods for validating Gaussian process emulators." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/19873/.

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Emulation is a statistical technique that can be utilised for estimating model simulations when the computer models are too computationally expensive to run. Emulators need to be subjected to a validation process since various assumptions have to be made. One assumption is that the computer model output is thought of as a realization of a Gaussian process with a mean and a covariance function. The computer model, however, is not a random sample from the Gaussian process distribution. In this thesis, we develop a graphical diagnostic that can be used to investigate whether the Gaussian process
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Andblom, Mikael. "Improved Differential Diagnostics Using Methods in Machine Learning and Regression." Thesis, KTH, Optimeringslära och systemteori, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-240083.

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There is a desire both from the patient and the society to have efficient tools for differential diagnostics. Mathematical relationships between diseases and observable consequences are defined in the thesis. Specifically artificial neural networks are considered in the modeling of the doctor’s methodology. To suggest further lab tests or symptoms to look for the network is inverted by looking at a minimization problem where the objective function gradient can be analytically calculated. Due to difficulties in obtaining real life medical data a program was constructed to generate artificial patient dat
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Kemp-Harper, Richard Owen. "Development of multiple-pulse NMR methods for investigation of sodium ions in vitro." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339303.

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Smagala, James A. "Novel bioinformatic methods for emerging pathogens with applications in influenza diagnostics." Connect to online resource, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3273816.

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Thesis (Ph.D.)--University of Colorado at Boulder, 2007.<br>Source: Dissertation Abstracts International, Volume: 68-07, Section: B, page: 4442. Adviser: Kathy L. Rowlen. Includes supplementary digital materials.
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Khodakovskiy, Nikita [Verfasser]. "Methods of ultra-fast laser contrast diagnostics and optimization / Nikita Khodakovskiy." Berlin : Freie Universität Berlin, 2020. http://d-nb.info/120492693X/34.

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17

SOFFRITTI, GIOVANNA. "Development of rapid molecular diagnostics methods for the agro-food sector." Doctoral thesis, Università Cattolica del Sacro Cuore, 2021. http://hdl.handle.net/10280/108769.

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L’elaborato è stato strutturato in base alle matrici analizzate. Il primo capitolo è dedicato alla caratterizzazione genetica e conseguente possibilità di utilizzo dei marcatori microsatellitari all’interno di 28 popolazioni locali di mais. L’analisi ha permesso di valutare lo stato di conservazione delle accessioni e realizzare un albero filogenetico per individuare le relazioni esistenti tra le diverse varietà. Su un numero più ridotto di materiali è stata valutata la possibilità di utilizzare i marcatori molecolari per la tracciabilità della filiera maidicola, in particolare farina destinat
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Marx, Douw. "Towards a hybrid approach for diagnostics and prognostics of planetary gearboxes." Diss., University of Pretoria, 2021. http://hdl.handle.net/2263/78157.

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The reliable operation of planetary gearboxes is critical for the sustained operation of many machines such as wind turbines and helicopter transmissions. Hybrid methods that make use of the respective advantages of physics-based and data-driven models can be valuable in addressing the unique challenges associated with the condition monitoring of planetary gearboxes. In this dissertation, a hybrid framework for diagnostics and prognostics of planetary gearboxes is proposed. The proposed framework aims to diagnose and predict the root crack length in a planet gear tooth from accelerometer meas
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Öberg, Månsson Ingrid. "Electroanalytical devices with fluidic control using textile materials and methods." Licentiate thesis, KTH, Fiberteknologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-279327.

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This thesis, written by Ingrid Öberg Månsson at KTH Royal Institute of Technology and entitled “Electroanalytical devices with fluidic control using textile materials and methods”, presents experimental studies on the development of textile based electronic devices and biosensors. One of the reasons why this is of interest is the growing demand for integrated smart products for wearable health monitoring or energy harvesting. To enable such products, new interdisciplinary fields arise combining traditional textile technology and electronics. Textile based devices have garnered much interest in
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Soukup, Patrik. "Diagnostika točivých elektrických strojů." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377107.

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The thesis Diagnostics of rotating electric machines deals with the theory of diagnostics of rotating machines, focusing especially on the diagnosis of asynchronous motors of high power. Due to the importance of maintaining the trouble-free condition of these machines with regard to serviceability, the importance of their diagnosis is growing. Due to inappropriate working conditions or for many other reasons, different types of malfunctions may occur in the machine. The list and the way of occurrence of possible failures are included and explained in this thesis. With the growing age of the ma
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Carnell, Mark Thomas. "The application of optical diagnostics to high energy electromagnetic acoustic transducers." Thesis, Loughborough University, 1995. https://dspace.lboro.ac.uk/2134/11239.

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This thesis is concerned with the design and construction of an electromagnetic acoustic transducer (EMAT) and the characterisation of its acoustic field both conventionally, using a hydrophone and with high resolution laser illuminated schlieren techniques. During the early 80s the introduction of the EMA T along with the other types of shock wave source used for lithotripsy, revolutionised the treatment of stone disease. The process of shock wave induced destruction of calculi and the use of shock waves in other areas of medicine will be discussed, along with the causes and effects of stone
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Loberg, John. "Novel Diagnostics and Computational Methods of Neutron Fluxes in Boiling Water Reactors." Doctoral thesis, Uppsala universitet, Tillämpad kärnfysik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-133238.

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The focus in this thesis is to improve knowledge of the BWR related uncertainties void, channel bow, and control rods. The presence of void determines the moderation of neutrons in BWRs. A high void fraction is less efficient in moderating neutrons than a low one. As a consequence, the ratio of thermal to fast neutrons is dependent on the surrounding void fraction. In this thesis, calculations with 2D/3D codes corroborate this dependence, the void correlation, to be linear and very robust to changes in different reactor parameters. The void fraction could be predicted from the ratio of simulta
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Harrison, Michael J. "The enhancement of intra-operative diagnostics and decision-making using computational methods." Thesis, University of Auckland, 2005. http://hdl.handle.net/2292/74.

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The data presented and views expressed in this document are the result of multiple published and unpublished studies over the last 25 years. My over-arching goal in this research was to use modern computing power to create functionally useful diagnoses, in real time, from the monitoring systems used during routine anaesthesia and to present these diagnoses in an ergonomic manner. In addition it was intended to incorporate into the anaesthetic monitor, expert systems that help with the management of uncommon situations. The Australian and New Zealand College guidelines on monitoring during anae
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SOAVE, Elia. "Diagnostics and prognostics of rotating machines through cyclostationary methods and machine learning." Doctoral thesis, Università degli studi di Ferrara, 2022. http://hdl.handle.net/11392/2490999.

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In the last decades, the vibration analysis has been exploited for monitoring many mechanical systems for industrial applications. Although several works demonstrated how the vibration based diagnostics may reach satisfactory results, the nowadays industrial scenario is deeply changing, driven by the fundamental need of time and cost reduction. In this direction, the academic research has to focus on the improvement of the computational efficiency for the signal processing techniques applied in the mechanical diagnostics field. In the same way, the industrial word requires an increasing attent
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Carvalho, Ricardo Jorge da Silva. "Revisiting molecular diagnostics of Streptococcus pneumoniae." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/16115.

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Mestrado em Biologia Molecular e Celular<br>Streptococcus pneumoniae is a human pathobiont that colonizes the nasopharynx. S. pneumoniae is responsible for causing non-invasive and invasive disease such as otitis, pneumonia, meningitis, and sepsis, being a leading cause of infectious diseases worldwide. Due to similarities with closely related species sharing the same niche, it may be a challenge to correctly distinguish S. pneumoniae from its relatives when using only non-culture based methods such as real time PCR (qPCR). In 2007, a molecular method targeting the major autolysin (lytA) of S.
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Lindberg, Martin. "Decision Support Systems: Diagnostics and Explanation methods : In the context of telecommunication networks." Thesis, Umeå universitet, Institutionen för fysik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-73666.

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This thesis work, conducted at Ericsson Software Research, aims to recommend a system setup for a tool to help troubleshooting personal at network operation centres (NOC) who monitors the telecom network. This thesis examines several different artificial intelligence algorithms resulting in the conclusion that Bayesian networks are suitable for the aimed system. Since the system will act as a decision support system it needs to be able to explain how recommendations have been developed. Hence a number of explanation methods have been examined. Unfortunately no satisfactory method was found and
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Rhen, Mats. "Studies of condition monitoring methods for system health assessment : health diagnostics and prognostics." Licentiate thesis, Luleå tekniska universitet, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-26751.

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Increasing interest in productivity, safety and environmental issues have highlighted the area of maintenance and reliability. The increasing cost of maintenance covers both preservation and sustainable exploitation of resources and awareness in maintaining equipment in a way to ensure return on investment both in the short and long run. The information obtained from condition monitoring of existing turbine, plant, rails and pumps can provide an important basis for dimensioning of future systems and components. The main objective of this research work is to develop and apply methods for effici
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Suwatthikul, Jittiwut. "A framework and methods for on-board network level fault diagnostics in automobiles." Thesis, University of Warwick, 2008. http://wrap.warwick.ac.uk/4102/.

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A significant number of electronic control units (ECUs) are nowadays networked in automotive vehicles to help achieve advanced vehicle control and eliminate bulky electrical wiring. This, however, inevitably leads to increased complexity in vehicle fault diagnostics. Traditional off-board fault diagnostics and repair at service centres, by using only diagnostic trouble codes logged by conventional onboard diagnostics, can become unwieldy especially when dealing with intermittent faults in complex networked electronic systems. This can result in inaccurate and time consuming diagnostics due to
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au, N. Williams@murdoch edu, and Nari Michelle Anderson. "DNA methods for the detection of Phytophthora cinnamomi from soil." Murdoch University, 2006. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070820.130155.

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This project assesses two aspects of DNA detection of Phytophthora species from soil samples. Firstly, a nested PCR protocol was established with both primary and nested PCR specific for P. cinnamomi detection. PCR amplification of P. cinnamomi DNA isolated from soil was optimised with the addition of bovine serum albumin and formamide. This was found to improve both the specificity and sensitivity of PCR amplification of DNA in the presence of inhibitors co-extracted along with the target DNA from soil samples. The application of diagnostic nested PCR with the addition of BSA and formamide wa
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Steltner, Holger. "Data analysis in respiratory medicine model selection and classification methods applied to clinical diagnostics /." [S.l.] : [s.n.], 2001. http://www.freidok.uni-freiburg.de/volltexte/324.

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Kvasniuk, D. I. "Using optio-polarizational methods and arthroscopy in early diagnostics and treatment of septic arthritis." Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19678.

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Hauschild, Anne-Christin [Verfasser], and Volkard [Akademischer Betreuer] Helms. "Computational methods for breath metabolomics in clinical diagnostics / Anne-Christin Hauschild. Betreuer: Volkard Helms." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2016. http://d-nb.info/1108255795/34.

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Novák, Jakub. "Diagnostika vybrané mostní konstrukce." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2019. http://www.nusl.cz/ntk/nusl-392122.

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The Diploma thesis deals with the Diagnostics of Reinforced Concrete Bridge in the village of Luhačovice. This thesis also describes the individual Diagnostic methods and instruments used in purpose to make Diagnosis of bridge constructions. The main aim of the Diagnostics is to determine the current state of the Bridge which consists in verification of the actual road structure, determination of the physical and mechanical parameters of the Concrete (strength, depth of carbonation) and in some parts of the bridge structure to determine the type, number and position of the bending or shear rei
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Brennecke, Johannes. "Molecular diagnostics of the bacterial response to antibiotic therapy." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28843.

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Bacterial bloodstream infections (BSIs) are a major healthcare problem causing high mortality and economic cost. BSIs require an immediate initiation of antibiotic therapy as any delay is associated with a mortality increase. With the emergence of antimicrobial resistance, the choice of the appropriate antibiotic becomes increasingly difficult, thus creating an urgent need for new diagnostics, ideally to be done at the point of care. The current gold standard is blood culture with subsequent susceptibility testing although several molecular methods have recently entered the market. However, in
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Ling, Daphne. "Alternative approaches to tuberculosis diagnostics research: methods for estimating the incremental value of new tests." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114458.

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Tuberculosis (TB) remains a global health problem. Diagnosis is the critical first step for control of TB, and several promising tests have been developed, including the interferon-gamma release assay (IGRA). Unfortunately, TB diagnostics research is still focused on measures of test accuracy (i.e. sensitivity and specificity). There are limited data on the incremental value of new tests over and above conventional tests and their impact on clinical management. Test accuracy data, while necessary, are only surrogates for patient-important outcomes and cannot provide high quality evidence f
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Metzger, A. Susanne. "Assurance of Indoor Environmental Quality through Building Diagnostics at Schematic Design." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/31057.

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With increasing knowledge about the indoor climate in recent years, preventive methods to avoid health problems caused by deficient building performance may become preferable to reactive methods. Benefits from preventive actions have been suggested for late building design phases, construction, and building operations, however, few data are available that demonstrate the benefits of preventive actions in early planning phases. <p> In a case study, expected building performance in respect to indoor air quality and thermal conditions in a large judicial facility in North America was evaluat
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Mignardi, Marco. "In situ Sequencing : Methods for spatially-resolved transcriptome analysis." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-110057.

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It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. In order to link the heterogeneity observed at molecular level with the morphological context of tissues, new methods are needed which achieve an additional level of information,
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Carrander, Claes. "Magnetizing Currents in Power Transformers : Measurements, Simulations, and Diagnostic Methods." Doctoral thesis, KTH, Elektroteknisk teori och konstruktion, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-208422.

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This thesis demonstrates a method for transformer core diagnostics. The method uses the no-load current of the transformer as an indicator, and gives different characteristic signatures for different types of faults or defects. Using the no-load current for the diagnostic gives high sensitivity. The method is therefore able to detect defects that are too small to have an impact on the losses. In addition to different types of fault, the method can in some cases also distinguish between faults in different locations within the core. Both single-phase and three-phase transformers can be diagnose
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Lalremruata, Albert [Verfasser]. "Development of molecular methods for screening Plasmodium infections : New diagnostics for the era of malaria elimination / Albert Lalremruata." Tübingen : Universitätsbibliothek Tübingen, 2021. http://d-nb.info/1226756301/34.

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Sjöstrand, Henrik. "Neutron Spectroscopy : Instrumentation and Methods for Fusion Plasmas." Doctoral thesis, Uppsala University, Department of Physics and Astronomy, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9296.

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<p>When the heavy hydrogen isotopes deuterium (D) and tritium (T) undergo nuclear fusion large amounts of energy are released. At the Joint European Torus (JET) research is performed on how to harvest this energy. Two of the most important fusion reactions, d+d→<sup>3</sup>He+n (E<sub>n</sub> = 2.5 MeV) and d+t→<sup>4</sup>He+n (E<sub>n</sub> = 14 MeV), produce neutrons. This thesis investigates how measurements of these neutrons can provide information on the fusion performance.</p><p>The Magnetic Proton Recoil (MPR) neutron spectrometer has operated at JET since 1996. The spectrometer was de
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Pedersen, Jan Egedal. "Fast ions in tokamaks and their collective measurement by collective Thomson scattering." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298419.

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Martin, Geoff W. "Quantitative spectroscopy of low temperature magnesium and titanium plasma plumes." Thesis, Queen's University Belfast, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300776.

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Kresak, Adam M. "The Technological History of Immunohistochemical Methods and Applications in Clinical Cancer Diagnosis and Research." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1531755545522738.

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Lama, Lara. "Novel methods for improving rapid paper-based protein assays with gold nanoparticle detection." Licentiate thesis, KTH, Proteomik och nanobioteknologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-214065.

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This thesis describes methods for improving sensitivity in rapid singleplex and multiplex microarray assays. The assays utilize the optical characteristics of colloidal gold nanoparticles for the colorimetric detection of proteins. Multiplexed detection in sandwich immunoassays is limited by cross-reactivity between different detection antibodies. The cross-reactivity between antibodies can contribute to increased background noise - decreasing the Limit-of-Detection of the assay - or generate false positive signals. Paper I shows improved assay sensitivity in a multiplexed vertical flow assay
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45

Nilsson, Andreas. "Future diagnostics of sepsis : Defining optimization methods in detection and quantification of circulating microRNA using the QIAcube and two-tailed RT-qPCR." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-20227.

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Sepsis, defined as a life-threatening organ dysfunction, is a condition triggered by an adverse immune reaction often leading to a considerable cost in human lives. A fast and early detection is the cornerstone for treating sepsis, however, current therapeutic standard relies on blood culturing, a slow and non-specific indicator. Modern research has heightened an interest in a new set of biomarkers collectively named, microRNA, to fight against sepsis induced mortality. MicroRNAs are highly stable in biofluids and attractive candidates as biomarkers due to being detectable by non-invasive mean
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46

Hoarty, David John. "Measurement of ion and electron populations in laser produced plasmas by x-ray absorption spectroscopy." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300085.

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47

Short, Robert Franklin. "Novel approaches in imaging and image-guided therapy microfabrication, quantitative diagnostic methods, and a model of lymphangiogenesis /." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1117553725.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xvi, 218 p.; also includes graphics (some col.). Includes bibliographical references (p. 200-218). Available online via OhioLINK's ETD Center
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Plan, Elodie L. "Pharmacometric Methods and Novel Models for Discrete Data." Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-150929.

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Pharmacodynamic processes and disease progression are increasingly characterized with pharmacometric models. However, modelling options for discrete-type responses remain limited, although these response variables are commonly encountered clinical endpoints. Types of data defined as discrete data are generally ordinal, e.g. symptom severity, count, i.e. event frequency, and time-to-event, i.e. event occurrence. Underlying assumptions accompanying discrete data models need investigation and possibly adaptations in order to expand their use. Moreover, because these models are highly non-linear,
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49

Hassan, Ibrahim Hamed Ibrahim [Verfasser]. "Performance Diagnostics Qu antitative Methods To Provide Training Consequences - Empirical Study To Deve lopment And Evaluation Field Team Sports / Ibrahim Hamed Ibrahim Hassan." Wuppertal : Universitätsbibliothek Wuppertal, 2013. http://d-nb.info/103362229X/34.

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50

Hindra, Matěj. "Diagnostické metody sledování plynů rozpuštěných v transformátorovém oleji." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230178.

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This thesis is devoted to analysis of the diagnostic methods used in practice. It is divided into two parts: theoretical and practical. The theoretical part concerns with the general description of the transformers. Further it provils informatik about systems for sampling oil from transformers with insulating oil – paper system. Another important part is the description of gas chromatography and TRANSPORT X. Description of the most appropriate evaluation methods for assessment of the state of the transformer is included as well.
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