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1

Rosenfeld, Michael E. "Inflammation and atherosclerosis: direct versus indirect mechanisms." Current Opinion in Pharmacology 13, no. 2 (2013): 154–60. http://dx.doi.org/10.1016/j.coph.2013.01.003.

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Pawlos, Agnieszka, Mateusz Niedzielski, Paulina Gorzelak-Pabiś, Marlena Broncel, and Ewelina Woźniak. "COVID-19: Direct and Indirect Mechanisms of Statins." International Journal of Molecular Sciences 22, no. 8 (2021): 4177. http://dx.doi.org/10.3390/ijms22084177.

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The virus responsible for the current COVID-19 pandemic is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a new virus with high infectivity and moderate mortality. The major clinical manifestation of COVID-19 is interstitial pneumonia, which may progress to acute respiratory distress syndrome (ARDS). However, the disease causes a potent systemic hyperin-flammatory response, i.e., a cytokine storm or macrophage activation syndrome (MAS), which is associated with thrombotic complications. The complexity of the disease requires appropriate intensive treatment. One of promising trea
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Tzani, Marina A., Dimitra K. Gioftsidou, Michael G. Kallitsakis, et al. "Direct and Indirect Chemiluminescence: Reactions, Mechanisms and Challenges." Molecules 26, no. 24 (2021): 7664. http://dx.doi.org/10.3390/molecules26247664.

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Emission of light by matter can occur through a variety of mechanisms. When it results from an electronically excited state of a species produced by a chemical reaction, it is called chemiluminescence (CL). The phenomenon can take place both in natural and artificial chemical systems and it has been utilized in a variety of applications. In this review, we aim to revisit some of the latest CL applications based on direct and indirect production modes. The characteristics of the chemical reactions and the underpinning CL mechanisms are thoroughly discussed in view of studies from the very recen
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Sarai, A., M. M. Gromiha, P. Prabakaran, S. Selvaraj, J. G. Siebers, and H. Kono. "Direct and indirect mechanisms in protein-DNA recognition." Seibutsu Butsuri 41, supplement (2001): S184. http://dx.doi.org/10.2142/biophys.41.s184_1.

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Mackowiak, Bryan, and Hongbing Wang. "Mechanisms of xenobiotic receptor activation: Direct vs. indirect." Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1859, no. 9 (2016): 1130–40. http://dx.doi.org/10.1016/j.bbagrm.2016.02.006.

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6

Kravitz, Alexxai V., and Anatol C. Kreitzer. "Striatal Mechanisms Underlying Movement, Reinforcement, and Punishment." Physiology 27, no. 3 (2012): 167–77. http://dx.doi.org/10.1152/physiol.00004.2012.

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Direct and indirect pathway striatal neurons are known to exert opposing control over motor output. In this review, we discuss a hypothetical extension of this framework, in which direct pathway striatal neurons also mediate reinforcement and reward, and indirect pathway neurons mediate punishment and aversion.
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Munneke, Jaap, Artem Belopolsky, and Jan Theeuwes. "Direct and Indirect Mechanisms of Value-Driven Attentional Guidance." Journal of Vision 16, no. 12 (2016): 82. http://dx.doi.org/10.1167/16.12.82.

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Nikolic-Paterson, David J., Shuang Wang, and Hui Yao Lan. "Macrophages promote renal fibrosis through direct and indirect mechanisms." Kidney International Supplements 4, no. 1 (2014): 34–38. http://dx.doi.org/10.1038/kisup.2014.7.

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Roncin, P., M. Barat, M. N. Gaboriaud, Z. S. Szilagyi, and A. K. Kazansky. "Direct and indirect stabilisation mechanisms in multiple electron capture." Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 98, no. 1-4 (1995): 275–79. http://dx.doi.org/10.1016/0168-583x(95)00125-5.

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Capon, C. J., M. Brown, and R. R. Boyce. "Direct and indirect charged aerodynamic mechanisms in the ionosphere." Advances in Space Research 62, no. 5 (2018): 1090–101. http://dx.doi.org/10.1016/j.asr.2018.06.007.

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Zhao, Hanyi, Yixiang Tian, Xiangyun Zhou, Luping Zhang, and Wei Meng. "Rating Regulatory Mechanism Effect Promotion under the Environmental Issuance Effects: Based on the Incentive Difference Hotelling Model." Sustainability 13, no. 10 (2021): 5368. http://dx.doi.org/10.3390/su13105368.

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Issuance effects are regarded as one of the most important aspects referring to the regulatory guidelines of green corporate bond ratings. This paper developed a new incentive difference Hotelling model, considering four major factors, i.e., the direct effect of issuance, the indirect effect of issuance, the reputation of rating agencies and the regulatory penalties. In this model, how the direct effect and the indirect effect impact the dual rating mechanism and the integrated rating mechanism was discussed. Numerical experiments were conducted to explore the regulatory effects on the two def
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Hamilton-Miller, J. M. T. "Immunopharmacology of Antibiotics: Direct and Indirect Immunomodulation of Defence Mechanisms." Journal of Chemotherapy 13, no. 2 (2001): 107–11. http://dx.doi.org/10.1179/joc.2001.13.2.107.

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13

Alvariño, J. M., F. J. Basterrechea, and A. Laganà. "Direct versus indirect microscopic mechanisms in the Li + HF reaction." Molecular Physics 59, no. 3 (1986): 559–68. http://dx.doi.org/10.1080/00268978600102251.

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Zinovchuk, A. V. "Direct and indirect mechanisms of auger recombination in n-InGaN." Technical Physics Letters 40, no. 5 (2014): 408–10. http://dx.doi.org/10.1134/s1063785014050277.

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Broughan, C. "Fragrant mechanisms The impact of odours — direct and indirect effects." International Journal of Aromatherapy 9, no. 4 (1999): 166–69. http://dx.doi.org/10.1016/s0962-4562(98)80061-1.

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Wang, Yongkai, Xiaojing Wen, Yu Qu, Tong Fu, and Zhongyue Zhang. "Direct and indirect coupling mechanisms in a chiral plasmonic system." Journal of Physics D: Applied Physics 49, no. 40 (2016): 405104. http://dx.doi.org/10.1088/0022-3727/49/40/405104.

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17

Wenderoth, Peter, and Syren Johnstone. "The different mechanisms of the direct and indirect tilt illusions." Vision Research 28, no. 2 (1988): 301–12. http://dx.doi.org/10.1016/0042-6989(88)90158-7.

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Donati, E. R., S. Porro, and P. H. Tedesco. "Direct and indirect mechanisms in the bacterial leaching of covellite." Biotechnology Letters 10, no. 12 (1988): 889–94. http://dx.doi.org/10.1007/bf01027001.

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19

Hartwig, A., R. D. Snyder, U. Kasten, R. Schlepegrell, and D. Beyersmann. "Direct and indirect mechanisms in cobalt genotoxicity in mammalian cells." Mutation Research/Environmental Mutagenesis and Related Subjects 271, no. 2 (1992): 121. http://dx.doi.org/10.1016/0165-1161(92)91098-c.

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Brisken, Cathrin, Sarabjeet Kaur, Tony E. Chavarria, et al. "Prolactin Controls Mammary Gland Development via Direct and Indirect Mechanisms." Developmental Biology 210, no. 1 (1999): 96–106. http://dx.doi.org/10.1006/dbio.1999.9271.

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Thron, Raymond W. "Direct and Indirect Exposure to Air Pollution." Otolaryngology–Head and Neck Surgery 114, no. 2 (1996): 281–85. http://dx.doi.org/10.1016/s0194-59989670184-5.

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Hazardous substances that originally are discharged as air pollutants may find their pathway to human exposure through multiple routes, including ingestion and dermal contact, as well as direct inhalation. The mechanisms for modeling and understanding the fate of air pollutants through atmospheric transport, deposition into water and soil, bioaccumulation, and ultimate uptake to receptor organs and systems in the human body are complex. Pollution prevention programs can be better engineered, pollution priorities can be identified, and greater environmental public health gains (attributable to
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Yu, Chunxiao, and Caroline Attardo Genco. "Fur-Mediated Global Regulatory Circuits in Pathogenic Neisseria Species." Journal of Bacteriology 194, no. 23 (2012): 6372–81. http://dx.doi.org/10.1128/jb.00262-12.

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ABSTRACTTheferricuptakeregulator (Fur) protein has been shown to function as a repressor of transcription in a number of diverse microorganisms. However, recent studies have established that Fur can function at a global level as both an activator and a repressor of transcription through both direct and indirect mechanisms. Fur-mediated indirect activation occurs via the repression of additional repressor proteins, or small regulatory RNAs, thereby activating transcription of a previously silent gene. Fur mediates direct activation through binding of Fur to the promoter regions of genes. Wherea
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Oaks, Adam W., and Anita Sidhu. "Parallel mechanisms for direct and indirect membrane protein trafficking by synucleins." Communicative & Integrative Biology 6, no. 6 (2013): e26794. http://dx.doi.org/10.4161/cib.26794.

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24

Bi, Y., and R. Yang. "Direct and Indirect Regulatory Mechanisms in TH17 cell Differentiation and Functions." Scandinavian Journal of Immunology 75, no. 6 (2012): 543–52. http://dx.doi.org/10.1111/j.1365-3083.2012.02686.x.

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25

Watkins, Derrick, Chiaolong Hsiao, Kristen Kruger Woods, Gerald B. Koudelka, and Loren Dean Williams. "P22 c2 Repressor−Operator Complex: Mechanisms of Direct and Indirect Readout‡." Biochemistry 47, no. 8 (2008): 2325–38. http://dx.doi.org/10.1021/bi701826f.

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26

Catalano, I. M., A. Cingolani, R. Cingolani, and M. Lepore. "Interband two-photon absorption mechanisms in direct and indirect GAP materials." Physica Scripta 37, no. 4 (1988): 579–82. http://dx.doi.org/10.1088/0031-8949/37/4/014.

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27

Egan, R. W., W. K. Hagmann, and P. H. Gale. "Naphthalenes as inhibitors of myeloperoxidase: Direct and indirect mechanisms of inhibition." Agents and Actions 29, no. 3-4 (1990): 266–76. http://dx.doi.org/10.1007/bf01966457.

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Xianghu Zhao, Jing Hu, Jie Liu, et al. "Direct or indirect action mechanisms of Naringin in maintaining bone homeostasis." Cellular and Molecular Biology 69, no. 6 (2023): 151–59. http://dx.doi.org/10.14715/cmb/2023.69.6.23.

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Fischer, Rico, Franziska Plessow, and Andrea Kiesel. "Auditory Warning Signals Affect Mechanisms of Response Selection." Experimental Psychology 57, no. 2 (2010): 89–97. http://dx.doi.org/10.1027/1618-3169/a000012.

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Irrelevant tone (accessory) stimuli facilitate performance in simple and choice reaction time tasks. In the present study, we combined accessory stimulation with a selective attention paradigm in order to investigate its influence on mechanisms of response selection. In the framework of a spatial stimulus-response compatibility task (Simon task), we tested whether accessory stimuli selectively affect bottom up triggered response activation processes (e.g., direct route processing), processing of task-relevant stimulus features (indirect route processing), or both/none. Results suggest a two-co
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Doksaki, Eftichia. "THE NEXUS BETWEEN FINANCIAL MECHANISMS AND ECONOMIC PERFORMANCE: EMPIRICAL EVIDENCE FROM GREECE." Entrepreneurship 12, no. 1 (2024): 27–39. http://dx.doi.org/10.37708/ep.swu.v12i1.4.

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The paper aims to investigate the impact of direct and indirect financial mechanisms on the economic performance of Greece over the period 1999-2019. Employing both bivariate analysis tools and the Generalized Method of Moments (GMM) technique, the study reveals diverse interactions among key macroeconomic factors. Direct finance, exemplified by heightened stock market activity, exhibits a positive impact on economic growth. Meanwhile, lagged inflation, indirect finance, and foreign direct investment emerge as significant contributors to inflation. Unemployment dynamics reveal a robust positiv
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Elma, Yusuf, Emine Yilmaz Can, Meryem Akpolat Ferah, and Mete Kececi. "The Monoacylglycerol Lipase Inhibitor JZL184 and ARDS: Differential Effects in Direct and Indirect Rat Models." Journal of Anesthesia & Pain Medicine 9, no. 4 (2024): 01–08. https://doi.org/10.33140/japm.09.04.03.

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Purpose: Acute respiratory distress syndrome (ARDS) leads to high morbidity and mortality, with limited pharmacological treatments and a reliance on supportive therapies. Recent evidence suggests cannabinoids may offer protective and therapeutic benefits against tissue damage, including lung pathologies. While cannabinoids' positive impacts on lung pathologies are known, their specific effects on ARDS mechanisms have not been thoroughly examined. The study purposes to explore the protective effects of cannabinoids on lung injury in direct and indirect ARDS models, focusing on differences in pa
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Xu, Jiamin, Zelong Li, Yuxin Zheng, et al. "OmniSR: Shadow Removal Under Direct and Indirect Lighting." Proceedings of the AAAI Conference on Artificial Intelligence 39, no. 8 (2025): 8887–95. https://doi.org/10.1609/aaai.v39i8.32961.

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Shadows can originate from occlusions in both direct and indirect illumination. Although most current shadow removal research focuses on shadows caused by direct illumination, shadows from indirect illumination are often just as pervasive, particularly in indoor scenes. A significant challenge in removing shadows from indirect illumination is obtaining shadow-free images to train the shadow removal network. To overcome this challenge, we propose a novel rendering pipeline for generating shadowed and shadow-free images under direct and indirect illumination, and create a comprehensive synthetic
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Ćavar Mišković, Filipa, and Goran Milas. "Mindfulness Reduces Adolescent Depression Through Stress Appraisal and Cognitive Reactivity: Evidence from a Four-Wave Longitudinal Study." Medicina 61, no. 7 (2025): 1154. https://doi.org/10.3390/medicina61071154.

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Background and Objectives: Adolescence is a critical yet vulnerable developmental stage, characterized by increased exposure to stressful life events (SLEs), which are strongly linked to the onset and progression of depression. Although mindfulness has been consistently associated with lower depressive symptoms, the mechanisms underlying this relationship—particularly in adolescents—remain underexplored. Prior research suggests that mindfulness operates through cognitive mechanisms, such as reduced rumination, enhanced emotional regulation, and greater cognitive flexibility. However, much of t
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Choe, Hwang, Yasuyuki Gondo, Ayaka Kasuga, et al. "The Relationship Between Social Interaction and Anxiety Regarding COVID-19 in Japanese Older Adults." Gerontology and Geriatric Medicine 9 (January 2023): 233372142311757. http://dx.doi.org/10.1177/23337214231175713.

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While previous studies suggest that women have higher anxiety than men regarding COVID-19, underlying mechanisms remain unclear. This study tries to explain the mechanisms by gender difference in social interaction based on a theory of social amplification of risk framework (SARF). We surveyed older adults in Japan regarding their anxiety regarding COVID-19, as well as the frequencies of their direct and indirect social interaction in July 2020 ( N = 1,587, aged 78–99 years). To explore the way in which gender and anxiety regarding COVID-19 were mediated by these two types of social interactio
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Bondareva, Lydia, and Nadezhda Kudryasheva. "Direct and Indirect Detoxification Effects of Humic Substances." Agronomy 11, no. 2 (2021): 198. http://dx.doi.org/10.3390/agronomy11020198.

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The review summarizes studies on the detoxification effects of water-soluble humic substances (HS), which are products of the natural transformation of organic substances in soils and bottom sediments that serve as natural detoxifying agents in water solutions. The detoxifying effects of HS on microorganisms are quite complex: HS neutralize free pollutants (indirect bioeffects) and also stimulate the protective response of organisms (direct bioeffects). Prospects and potential problems of bioluminescent bacteria-based assay to monitor toxicity of solutions in the presence of HS are discussed.
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Homburg, Christian, Arnd Vomberg, and Stephan Muehlhaeuser. "Design and Governance of Multichannel Sales Systems: Financial Performance Consequences in Business-to-Business Markets." Journal of Marketing Research 57, no. 6 (2020): 1113–34. http://dx.doi.org/10.1177/0022243720929676.

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Multichannel sales systems in business-to-business markets vary substantially in their designs and thereby either attenuate or aggravate agency conflicts between manufacturers and sales partners. Drawing on multiple agency theory, the authors introduce direct and indirect channel usage as focal design dimensions of multichannel sales systems and investigate each channel’s performance effects using a matched manufacturer–sales partner data set. Whereas direct channel usage predominantly lowers agency conflicts in terms of information asymmetry and sales partner moral hazard, indirect channel us
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Jain, Kalpna, Shyam Kishor, Khundrakpam S. Singh, Michael Odelius, and Lavanya M. Ramaniah. "Quantum dots as an electron or hole acceptor: on some factors affecting charge transfer in dye–quantum dot composites." Physical Chemistry Chemical Physics 20, no. 42 (2018): 27036–48. http://dx.doi.org/10.1039/c8cp04577a.

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Piotrowska, Maria. "DIRECT AND INDIRECT EFFECTS OF PRO-POOR GROWTH." Buletin Ekonomi Moneter dan Perbankan 18, no. 3 (2016): 251–80. http://dx.doi.org/10.21098/bemp.v18i3.548.

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Balancing sustainable growth requires poverty to be reduced. The paper is aimed at determining under which conditions growth can be considered pro-poor. Own approaching to the definition of pro-poor growth is suggested. It allows identifying the growth factors, which directly reduce poverty. Furthermore, it analyses two transmission mechanisms through which growth can reduce poverty; a labor market and local redistribution. It reveals barriers in poverty reduction thus pointing at necessary state intervention. It also helps to evaluate if the sectors of strongest foreign direct investments con
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Mendelevich, Elena G., Alsu A. Saifeeva, and Artur I. Kurbanov. "COVID-19-associated orthostatic hypotension syndrome: direct and indirect mechanisms of development." Neurology Bulletin LIII, no. 3 (2021): 64–70. http://dx.doi.org/10.17816/nb81629.

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Background. The article presents an observation of the clinical case of orthostatic hypotension that developed after an infection caused by the SARS-CoV-2 virus. The issues of etiology, pathogenesis, diagnosis are outlined. The complexity of diagnosis at the stage of clinical observation is due to the comorbidity of possible mechanisms and the difficulty of determining the primary factor. Taking into account the study of variants of direct and indirect action of this 2019-nCoV, the description of the clinical observation of orthostatic hypotension supplements the data on the spectrum of manife
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Leyko, M., F. Nicoud, and T. Poinsot. "Comparison of Direct and Indirect Combustion Noise Mechanisms in a Model Combustor." AIAA Journal 47, no. 11 (2009): 2709–16. http://dx.doi.org/10.2514/1.43729.

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Sánchez-de-Armas, Rocío, Jaime Oviedo, Miguel Ángel San Miguel, and Javier Fdez Sanz. "Direct vs Indirect Mechanisms for Electron Injection in Dye-Sensitized Solar Cells." Journal of Physical Chemistry C 115, no. 22 (2011): 11293–301. http://dx.doi.org/10.1021/jp201233y.

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Yu, Ting, and Fuxing Zeng. "Chloramphenicol Interferes with 50S Ribosomal Subunit Maturation via Direct and Indirect Mechanisms." Biomolecules 14, no. 10 (2024): 1225. http://dx.doi.org/10.3390/biom14101225.

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Chloramphenicol (CAM), a well-known broad-spectrum antibiotic, inhibits peptide bond formation in bacterial ribosomes. It has been reported to affect ribosome assembly mainly through disrupting the balance of ribosomal proteins. The present study investigates the multifaceted effects of CAM on the maturation of the 50S ribosomal subunit in Escherichia coli (E. coli). Using label-free quantitative mass spectrometry (LFQ-MS), we observed that CAM treatment also leads to the upregulation of assembly factors. Further cryo-electron microscopy (cryo-EM) analysis of the ribosomal precursors character
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Nakano, Nobuhiro, Chiharu Nishiyama, Ko Okumura, Shigaku Ikeda, and Hideoki Ogawa. "Notch signaling augments mast cell cytokine production by direct and indirect mechanisms." Journal of Dermatological Science 69, no. 2 (2013): e73. http://dx.doi.org/10.1016/j.jdermsci.2012.11.525.

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Sánchez-de-Armas, R., M. A. San-Miguel, J. Oviedo, and J. Fdez Sanz. "Direct vs. indirect mechanisms for electron injection in DSSC: Catechol and alizarin." Computational and Theoretical Chemistry 975, no. 1-3 (2011): 99–105. http://dx.doi.org/10.1016/j.comptc.2011.01.010.

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Klippenstein, Stephen J., and James T. Hynes. "Direct and indirect solvent coupling vibrational dephasing mechanisms in hydrogen-bonded molecules." Journal of Physical Chemistry 95, no. 12 (1991): 4651–59. http://dx.doi.org/10.1021/j100165a013.

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Zhou, Peng, Anna Santoro, Odile D. Peroni, et al. "PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms." Journal of Clinical Investigation 129, no. 10 (2019): 4138–50. http://dx.doi.org/10.1172/jci127092.

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Shah, Shaheen, and Ce Hao. "Density functional theory study of direct and indirect photodegradation mechanisms of sulfameter." Environmental Science and Pollution Research 23, no. 19 (2016): 19921–30. http://dx.doi.org/10.1007/s11356-016-6956-y.

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Wang, Ji Ming, Luoling Xu, William J. Murphy, Dennis D. Taub, and Oleg Chertov. "IL-8-Induced T-Lymphocyte Migration: Direct as Well as Indirect Mechanisms." Methods 10, no. 1 (1996): 135–44. http://dx.doi.org/10.1006/meth.1996.0087.

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Tam, Robert C., Johnson YN Lau, and Zhi Hong. "Mechanisms of Action of Ribavirin in Antiviral Therapies." Antiviral Chemistry and Chemotherapy 12, no. 5 (2001): 261–72. http://dx.doi.org/10.1177/095632020101200501.

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Although ribavirin was originally synthesized over 30 years ago and has been used to treat viral infections as monotherapy (respiratory syncytial virus and Lassa fever virus) or with interferon-α (IFN-α) as combination therapy (hepatitis C virus), the precise mechanism of its therapeutic activities remains controversial. In this review we focus on two main biological properties of ribavirin: its indirect and direct antiviral activities (with particular emphasis on its efficacy against chronic hepatitis C infection). Each property could individually or collectively account for its clinical effi
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Sánchez-Bayo, Francisco. "Indirect Effect of Pesticides on Insects and Other Arthropods." Toxics 9, no. 8 (2021): 177. http://dx.doi.org/10.3390/toxics9080177.

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Pesticides released to the environment can indirectly affect target and non-target species in ways that are often contrary to their intended use. Such indirect effects are mediated through direct impacts on other species or the physical environment and depend on ecological mechanisms and species interactions. Typical mechanisms are the release of herbivores from predation and release from competition among species with similar niches. Application of insecticides to agriculture often results in subsequent pest outbreaks due to the elimination of natural enemies. The loss of floristic diversity
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