Einloggen

Thematische Bibliographien / DNBSEQ-G400 / Zeitschriftenartikel

Um die anderen Arten von Veröffentlichungen zu diesem Thema anzuzeigen, folgen Sie diesem Link: DNBSEQ-G400.

Zeitschriftenartikel zum Thema „DNBSEQ-G400“

Autor: Grafiati

Veröffentlicht am 4. Juni 2025

Zuletzt aktualisiert am 1. August 2025

Geben Sie eine Quelle nach APA, MLA, Chicago, Harvard und anderen Zitierweisen an

Wählen Sie eine Art der Quelle aus:

Machen Sie sich mit Top-37 Zeitschriftenartikel für die Forschung zum Thema "DNBSEQ-G400" bekannt.

Neben jedem Werk im Literaturverzeichnis ist die Option "Zur Bibliographie hinzufügen" verfügbar. Nutzen Sie sie, wird Ihre bibliographische Angabe des gewählten Werkes nach der nötigen Zitierweise (APA, MLA, Harvard, Chicago, Vancouver usw.) automatisch gestaltet.

Sie können auch den vollen Text der wissenschaftlichen Publikation im PDF-Format herunterladen und eine Online-Annotation der Arbeit lesen, wenn die relevanten Parameter in den Metadaten verfügbar sind.

Sehen Sie die Zeitschriftenartikel für verschiedene Spezialgebieten durch und erstellen Sie Ihre Bibliographie auf korrekte Weise.

1

Sun, Xiaohuan, Yue-Hua Hu, Jingjing Wang, et al. "Efficient and stable metabarcoding sequencing data using a DNBSEQ-G400 sequencer validated by comprehensive community analyses." Gigabyte 2021 (March 19, 2021): 1–15. http://dx.doi.org/10.46471/gigabyte.16.

Der volle Inhalt der Quelle

Annotation:

Metabarcoding is a widely used method for fast characterization of microbial communities in complex environmental samples. However, the selction of sequencing platform can have a noticeable effect on the estimated community composition. Here, we evaluated the metabarcoding performance of a DNBSEQ-G400 sequencer developed by MGI Tech using 16S and internal transcribed spacer (ITS) markers to investigate bacterial and fungal mock communities, as well as the ITS2 marker to investigate the fungal community of 1144 soil samples, with additional technical replicates. We show that highly accurate seq

APA, Harvard, Vancouver, ISO und andere Zitierweisen

2

Konanov, Dmitry N., Vera Y. Tereshchuk, Ignat V. Sonets, et al. "Analysis of Software Read Cross-Contamination in DNBSEQ Data." Biology 14, no. 6 (2025): 670. https://doi.org/10.3390/biology14060670.

Der volle Inhalt der Quelle

Annotation:

DNA nanoball sequencing (DNBSEQ) is one of the most rapidly developing sequencing technologies and is widely applied in genomic and transcriptomic investigations. Recently, a new PE300 sequencing option primarily recommended for amplicon analysis was released for DNBSEQ-G99 and G400 devices. Given their unprecedentedly high data yield per flow cell, the new PE300 kits could be a great choice for various sequencing tasks, but we found that combining different types of DNA libraries in a single run could lead to undesired artifacts in the data. In this study, we investigate the occasional read c

APA, Harvard, Vancouver, ISO und andere Zitierweisen

3

Makarova, M. V., M. V. Nemtsova, M. S. Belenikin, et al. "The diagnosis of hereditary cancer syndromes with atypical manifestation: clinical cases." Malignant tumours 13, no. 4 (2023): 93–100. http://dx.doi.org/10.18027/2224-5057-2023-13-4-93-100.

Der volle Inhalt der Quelle

Annotation:

Background: Germinal pathogenic variants are the cause of the development of hereditary cancer syndromes (HCS). Various genetic tests are used for HCS detect, from the «frequent» mutations of one or several genes analysis to the full-length gene sequence, next-generation sequencing (NGS) based panel, whole exome (WES) or whole genome sequencing (WGS).There are some HCS cases with atypical clinical manifestations and the family history does not allow one to suspect a specific HCS and limit oneself to the study of only one or a few genes. Conducting research using NGS to assess the selected samp

APA, Harvard, Vancouver, ISO und andere Zitierweisen

4

Pavlova, Anna, Vera Belova, Robert Afasizhev, Irina Bulusheva, Denis Rebrikov, and Dmitriy Korostin. "Runcer-Necromancer: a method to rescue data from an interrupted run on MGISEQ-2000." F1000Research 10 (January 14, 2021): 22. http://dx.doi.org/10.12688/f1000research.27763.1.

Der volle Inhalt der Quelle

Annotation:

During the sequencing process, problems can occur with any device, including the MGISEQ-2000 (DNBSEQ-G400) platform. We encountered a power outage that resulted in a temporary shutdown of a sequencer in the middle of the run. Since barcode reading in MGISEQ-2000 takes place at the end of the run, it was impossible to use non-demultiplexed raw data. We decided to completely use up the same cartridge with reagents and flow cell loaded with DNB and started a new run in a shortened custom mode. We figured out how the MGISEQ-2000 converts preliminary data in .cal format into .fastq files and wrote

APA, Harvard, Vancouver, ISO und andere Zitierweisen

5

Pavlova, Anna, Vera Belova, Robert Afasizhev, Irina Bulusheva, Denis Rebrikov, and Dmitriy Korostin. "Runcer-Necromancer: a method to rescue data from an interrupted run on MGISEQ-2000." F1000Research 10 (February 14, 2022): 22. http://dx.doi.org/10.12688/f1000research.27763.2.

Der volle Inhalt der Quelle

Annotation:

During the sequencing process, problems can occur with any device, including the MGISEQ-2000 (DNBSEQ-G400) platform. We encountered a power outage that resulted in a temporary shutdown of a sequencer in the middle of the run. Since barcode reading in MGISEQ-2000 takes place at the end of the run, it was impossible to use non-demultiplexed raw data. We decided to completely use up the same cartridge with reagents and flow cell loaded with DNB and started a new run in a shortened custom mode. We figured out how the MGISEQ-2000 converts preliminary data in .cal format into .fastq files and wrote

APA, Harvard, Vancouver, ISO und andere Zitierweisen

6

Haars, Jonathan, Navaneethan Palanisamy, Frans Wallin, et al. "Prevalence of SARS-CoV-2 Omicron Sublineages and Spike Protein Mutations Conferring Resistance against Monoclonal Antibodies in a Swedish Cohort during 2022–2023." Microorganisms 11, no. 10 (2023): 2417. http://dx.doi.org/10.3390/microorganisms11102417.

Der volle Inhalt der Quelle

Annotation:

Monoclonal antibodies (mAbs) are an important treatment option for COVID-19 caused by SARS-CoV-2, especially in immunosuppressed patients. However, this treatment option can become ineffective due to mutations in the SARS-CoV-2 genome, mainly in the receptor binding domain (RBD) of the spike (S) protein. In the present study, 7950 SARS-CoV-2 positive samples from the Uppsala and Örebro regions of central Sweden, collected between March 2022 and May 2023, were whole-genome sequenced using amplicon-based sequencing methods on Oxford Nanopore GridION, Illumina MiSeq, Illumina HiSeq, or MGI DNBSEQ

APA, Harvard, Vancouver, ISO und andere Zitierweisen

7

Ульянова, Татьяна, Индира Бейшова, Диляра Гриценко та ін. "РЕСЕКВЕНИРОВАНИЕ ПОЛНОГО ГЕНОМА КРУПНОГО РОГАТОГО СКОТА КАЗАХСКОЙ БЕЛОГОЛОВОЙ ПОРОДЫ". Ġylym ža̋ne bìlìm 2, № 3(76) (2024): 130–40. https://doi.org/10.52578/2305-9397-2024-3-2-130-140.

Der volle Inhalt der Quelle

Annotation:

В статье представлена характеристика первой полученной последовательности генома крупного рогатого скота казахской белоголовой породы в Казахстане. Целью работы было провести ресеквенирование крупного рогатого скота казахской белоголовой породы, разводимой в Республике Казахстан. Были собраны образцы цельной крови и волосяных луковиц наиболее типичных эталонных представителей казахской белоголовой породы. Для проведения полногеномного ресеквенирования выделена ДНК из образцов отобранного биоматериала с использованием коммерческих наборов «ДНК Экстран-2» (ООО «Синтол», РФ), «PureLink Genomic DN

APA, Harvard, Vancouver, ISO und andere Zitierweisen

8

Dolotkazin, D. R., D. A. Averinskaya, E. N. Knyazev, et al. "Assessment of miR-21-5p, miR-451a, and miR-144-3p level in urine in differential diagnosis of localized prostate cancer." Cancer Urology 20, no. 1 (2024): 36–43. http://dx.doi.org/10.17650/1726-9776-2024-20-1-36-43.

Der volle Inhalt der Quelle

Annotation:

Background. Limited sensitivity and specificity of existing prostate cancer (PCa) diagnosis methods drive the search for new markers. A number of studies has demonstrated the potential for measuring expression of certain microRNAs in urine.Aim. To evaluate the diagnostic potential of measuring microRNA expression in urine in PCa.Materials and methods. A collection of urine sediment samples from 19 patients with benign prostatic hyperplasia and 44 patients with PCa was analyzed. RNA was isolated using the miRNEasy Serum/Plasma Kit. 16 µL of RNA isolated from each sample were converted into cDNA

APA, Harvard, Vancouver, ISO und andere Zitierweisen

9

Shimansky, Valentin, Oleg Popov, Alexander Kel, et al. "Analysis of the Expression Profile in COVID-19 Patients in the Russian Population Considering Disease Severity, Mortality, and Cytokine Storm." Biomedicines 13, no. 4 (2025): 863. https://doi.org/10.3390/biomedicines13040863.

Der volle Inhalt der Quelle

Annotation:

Background/Objectives: The COVID-19 pandemic has posed a significant challenge to global healthcare systems and has prompted a need for a better understanding of the molecular mechanisms underlying SARS-CoV-2 infection. This study aims to analyze differential gene expression in COVID-19 patients to identify regulatory genes influencing key pathways involved in disease progression. Methods: We conducted a transcriptomic analysis of patients admitted to the Infectious Disease Department of City Hospital No. 40, confirmed with SARS-CoV-2 via PCR. The study received ethical approval (protocol No.

APA, Harvard, Vancouver, ISO und andere Zitierweisen

10

Gervas, P. A., A. Yu Molokov, N. N. Babyshkina, et al. "Whole exome sequencing: the search for mutations associated with hereditary breast cancer in ethnic groups of Siberia." Siberian journal of oncology 23, no. 5 (2024): 35–46. http://dx.doi.org/10.21294/1814-4861-2024-23-5-35-46.

Der volle Inhalt der Quelle

Annotation:

Hereditary breast cancer (HBC) is a heterogeneous disease caused by mutations in genes characterized by ethnic specifcity. The clinical heterogeneity of this disease signifcantly complicates its diagnosis. The use of high-throughput sequencing is one of the approaches that allow the search for genes and their variants associated with the development of HBC. The purpose of the study was to search for new genes associated with HBC in the understudied ethnic groups of Siberia by using whole exome sequencing (WES).Material and Methods. WES was performed on a cohort of 16 probands with BC (Tuvan, Y

APA, Harvard, Vancouver, ISO und andere Zitierweisen

11

Ogarkov, O. B., A. E. Suzdalnitsky, I. G. Kondratov, et al. "Isolation and whole genome sequencing of a lipophilic anaerobic bacterium, a representative of the species complex <i>Corynebacterium tuberculostearicum</i>, from a tuberculosis focus." Acta Biomedica Scientifica 8, no. 4 (2023): 12–19. http://dx.doi.org/10.29413/abs.2023-8.4.2.

Der volle Inhalt der Quelle

Annotation:

Background. The study of the lower respiratory tract microbiome has been actively developed inrecent years with the help of whole genome sequencing (WGS) methods. Due to this, it became clear that the nature of the lungs microbiota is very different from other microbial communities inhabiting the human body. One of the important directions in the study of pathological lungs biocenosis is the study of the role of the satellite microbiota of the tuberculosis focus. The aim of the work. To isolate and characterize oxygen-tolerant anaerobes from the necrotic contents of tuberculomas. Materials and

APA, Harvard, Vancouver, ISO und andere Zitierweisen

12

Safika, Safika, Agustin Indrawati, Rahmat Hidayat, and Alif Puarada. "<b>Characterizing the gut microbiome of birds-of-paradise in the northwest lowland of Papua Island</b>." Open Veterinary Journal 14, no. 12 (2024): 3345. https://doi.org/10.5455/ovj.2024.v14.i12.19.

Der volle Inhalt der Quelle

Annotation:

Background: Birds-of-paradise, renowned for their stunning plumage and intricate mating rituals, have been extensively studied for their external characteristics. However, the microbial communities inhabiting their digestive tracts remain largely unexplored. The gut microbiome plays a vital role in host health and physiology, influencing digestion, nutrient absorption, and immune function. Understanding the microbiome of birds-of-paradise, particularly in their unique tropical rainforest habitats, may offer valuable insights into their adaptation and overall health. Aim: This study aims to cha

APA, Harvard, Vancouver, ISO und andere Zitierweisen

13

Maekawa, Shigekatsu, Masahi Fujita, Ryo Takata, et al. "Abstract 1416: Genomic features of renal cell carcinoma developed during end-stage renal disease and dialysis." Cancer Research 83, no. 7_Supplement (2023): 1416. http://dx.doi.org/10.1158/1538-7445.am2023-1416.

Der volle Inhalt der Quelle

Annotation:

Abstract Introduction: Patients with end-stage renal disease (ESRD) or receiving dialysis have a much higher risk for renal cell carcinoma (RCC), but carcinogenic mechanisms and genomic features remain little explored and undefined. This study’s goal was to identify the genomic features of ESRD RCC and characterize them for associations with tumor histology and dialysis exposure. In this study, we obtained 33 RCCs, with various histological subtypes, that developed in ESRD patients receiving dialysis and performed whole-genome sequencing and transcriptome analyses. Materials and Methods: Froze

APA, Harvard, Vancouver, ISO und andere Zitierweisen

14

Izawa, Masao, and Fuminori Taniguchi. "ODP403 Diversity of Estrogen-Responsive Genes in Endometriotic Lesions." Journal of the Endocrine Society 6, Supplement_1 (2022): A657—A658. http://dx.doi.org/10.1210/jendso/bvac150.1359.

Der volle Inhalt der Quelle

Annotation:

Abstract Background Endometriosis has been accepted as an estrogen-dependent disease for more than two decades. So far, estrogen modulators that targeting estrogen depletion in endometriotic lesions have been expected as the first option of treatments to improve the symptoms associated with endometriosis. However, the limits of treatment are becoming apparent. Objective As the background of limits, we hypothesized the heterogeneity of genetic and/or epigenetic environments in endometriotic lesions (1). To test our hypothesis, we examined the expression profile of estrogen-responsive genes usin

APA, Harvard, Vancouver, ISO und andere Zitierweisen

15

Scorilas, Andreas, Katerina-Marina Pilala, Panagiotis Tsiakanikas, et al. "Abstract 3337: Unveiling m6A epitranscriptome-related genomic variations in bladder cancer: predictive biomarkers for disease progression and treatment outcome towards tailored therapeutics." Cancer Research 85, no. 8_Supplement_1 (2025): 3337. https://doi.org/10.1158/1538-7445.am2025-3337.

Der volle Inhalt der Quelle

Annotation:

Abstract Due to its highly heterogenous molecular landscape, bladder cancer (BlCa) is still characterized by non-personalized prognosis and treatment decisions. N6-methyladenosine (m6A) has emerged as the most common and conserved internal mRNA modification, regulating RNA metabolism and translation. Herein, we have profiled mutations and copy number variations (CNVs) within m6A RNA machinery genes and assessed their clinical relevance in BlCa patients’ prognosis and treatment outcome. DNA-seq libraries were prepared from 96 bladder specimens (tumors: n=87; normal urothelium: n=9) using a cust

APA, Harvard, Vancouver, ISO und andere Zitierweisen

16

Uemura, Yu, Miwako Nishio, Runa Shimomaki, et al. "The Potential of Plasma CXCL10 As a Biomarker That Reflects Pathogenesis and Prognosis in Systemic Chronic Active EBV Disease." Blood 144, Supplement 1 (2024): 2969. https://doi.org/10.1182/blood-2024-209612.

Der volle Inhalt der Quelle

Annotation:

Background and Purpose: Systemic Chronic Active Epstein-Barr Virus disease (sCAEBV) is a refractory disease characterized by the activation and clonal proliferation of EBV-infected T or NK cells, leading to a progressive and fatal course. The primary clinical feature is persistent systemic inflammation. Its only curative treatment is hematopoietic stem cell transplantation (Blood Adv. 2020;4:2918), but following disease activities of inflammatory symptoms are poor prognostic factors after the treatment: fever, elevated ALT, vasculitis, uveitis, and progressive skin lesions. Elucidating the mec

APA, Harvard, Vancouver, ISO und andere Zitierweisen

17

Anna, Pavlova. "runcer-necromancer." December 11, 2020. https://doi.org/10.5281/zenodo.4316802.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

18

Zhang, Zhidong, Jing Zhu, Osman Ghenijan, Jianwei Chen, Yuxian Wang, and Ling Jiang. "Prokaryotic taxonomy and functional diversity assessment of different sequencing platform in a hyper-arid Gobi soil in Xinjiang Turpan Basin, China." Frontiers in Microbiology 14 (November 14, 2023). http://dx.doi.org/10.3389/fmicb.2023.1211915.

Der volle Inhalt der Quelle

Annotation:

Turpan Basin located in the eastern Xinjiang is a typical arid inland basin with extremely scarce water resources and a fragile ecosystem. Prokaryotic communities with unique genetic and physiological modifications can survive and function in such harsh environments, offering diverse microbial resources. However, numerous microbes can enter the viable but non-culturable state because of drought stress in the desert soil. In this work, next generation sequencing (NGS) technology based on DNA nanoball sequencing platform (DNBSEQ-G400) and sequencing-by-synthesis platform (NovaSeq 6000) were appl

APA, Harvard, Vancouver, ISO und andere Zitierweisen

19

Naval-Sanchez, Marina, Nikita Deshpande, Minh Tran, et al. "Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions." Frontiers in Molecular Biosciences 9 (July 7, 2022). http://dx.doi.org/10.3389/fmolb.2022.900323.

Der volle Inhalt der Quelle

Annotation:

Background: Chromatin falls into one of two major subtypes: closed heterochromatin and euchromatin which is accessible, transcriptionally active, and occupied by transcription factors (TFs). The most widely used approach to interrogate differences in the chromatin state landscape is the Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq). While library generation is relatively inexpensive, sequencing depth requirements can make this assay cost-prohibitive for some laboratories.Findings: Here, we benchmark data from Beijing Genomics Institute’s (BGI) DNBSEQ-G400 low-cost sequ

APA, Harvard, Vancouver, ISO und andere Zitierweisen

20

Póliska, Szilárd, Chahra Fareh, Adél Lengyel, Loránd Göczi, József Tőzsér, and Istvan Szatmari. "Comparative transcriptomic analysis of Illumina and MGI next-generation sequencing platforms using RUNX3- and ZBTB46-instructed embryonic stem cells." Frontiers in Genetics 14 (January 5, 2024). http://dx.doi.org/10.3389/fgene.2023.1275383.

Der volle Inhalt der Quelle

Annotation:

Introduction: We have previously observed phenotypic and developmental changes upon the ectopic expression of the RUNX3 or the ZBTB46 transcription factors in mouse embryonic stem cell (ESC) derived progenitors. In this study, we evaluated the gene expression profiles of the RUNX3- and the ZBTB46-instructed murine ESCs with RNA-seq testing two next-generation sequencing technologies.Methods: We compared the DNA nanoball-based DNBSEQ G400 sequencer (MGI) with the bridge-PCR-based NextSeq 500 instrument (Illumina) for RNA sequencing. Moreover, we also compared two types of MGI sequencing reagent

APA, Harvard, Vancouver, ISO und andere Zitierweisen

21

Jia, Yangyang, Shengguo Zhao, Wenjie Guo, et al. "Sequencing introduced false positive rare taxa lead to biased microbial community diversity, assembly, and interaction interpretation in amplicon studies." Environmental Microbiome 17, no. 1 (2022). http://dx.doi.org/10.1186/s40793-022-00436-y.

Der volle Inhalt der Quelle

Annotation:

Abstract Background Increasing studies have demonstrated potential disproportionate functional and ecological contributions of rare taxa in a microbial community. However, the study of the microbial rare biosphere is hampered by their inherent scarcity and the deficiency of currently available techniques. Sample-wise cross contaminations might be introduced by sample index misassignment in the most widely used metabarcoding amplicon sequencing approach. Although downstream bioinformatic quality control and clustering or denoising algorithms could remove sequencing errors and non-biological art

APA, Harvard, Vancouver, ISO und andere Zitierweisen

22

Шмитко, А. О., И. А. Булушева, Ю. А. Василиадис, et al. "Razrabotka kastomnyh barkodov dlya sekvenirovaniya na platforme MGI." Вестник Российского государственного медицинского университета, no. 2024(5) (October 2024). http://dx.doi.org/10.24075/vrgmu.2024.040.

Der volle Inhalt der Quelle

Annotation:

Platforma sekvenirovaniya sleduyushchego pokoleniya MGI (MGI Tech Co. Ltd., Kitaj), vklyuchayushchaya sekvenatory DNBSEQ-G50, -G400 i -T7, aktivno vnedryaetsya v nauchnye issledovaniya. Odnako sohranyayutsya ogranicheniya, svyazannye s ispol'zovaniem standartnyh barkodov, v chastnosti, na kolichestvo odnovremenno sekveniruemyh obrazcov i na sootnoshenie ih kolichestva, a takzhe prisutstvuet problema sovmestimosti barkodov iz raznyh ili nepolnyh setov. Cel'yu raboty bylo razrabotat' universal'nyj metod, pozvolyayushchij sekvenirovat' do 252 obrazcov odnovremenno na odnoj dorozhke sekvenatora, s

APA, Harvard, Vancouver, ISO und andere Zitierweisen

23

Hosoi, Sayaka, Takako Hirose, Shoji Matsumura, et al. "Effect of sequencing platforms on the sensitivity of chemical mutation detection using Hawk-Seq™." Genes and Environment 46, no. 1 (2024). http://dx.doi.org/10.1186/s41021-024-00313-9.

Der volle Inhalt der Quelle

Annotation:

Abstract Background Error-corrected next-generation sequencing (ecNGS) technologies have enabled the direct evaluation of genome-wide mutations after exposure to mutagens. Previously, we reported an ecNGS methodology, Hawk-Seq™, and demonstrated its utility in evaluating mutagenicity. The evaluation of technical transferability is essential to further evaluate the reliability of ecNGS-based assays. However, cutting-edge sequencing platforms are continually evolving, which can affect the sensitivity of ecNGS. Therefore, the effect of differences in sequencing instruments on mutation data qualit

APA, Harvard, Vancouver, ISO und andere Zitierweisen

24

Shmitko, AO, IA Bulusheva, YuA Vasiliadis, et al. "Designing of custom barcodes for sequencing on the MGI platform." Bulletin of Russian State Medical University, no. 2024(5) (October 2024). http://dx.doi.org/10.24075/brsmu.2024.040.

Der volle Inhalt der Quelle

Annotation:

The MGI (MGI Tech Co. Ltd., China) next-generation sequencing platform, including the DNBSEQ-G50, -G400, and -T7 sequencers, is being actively adopted in research. Despite its widespread adoption, challenges persist in the form of limitations associated with the manufacturer's provided barcode set for library preparation. These limitations include constraints on the number of samples that can be concurrently sequenced, compatibility issues with barcodes from diverse or incomplete sets, and restrictions on the sample ratio. Purpose: to develop a universal method that allows sequencing of up to

APA, Harvard, Vancouver, ISO und andere Zitierweisen

25

Meslier, Victoria, Benoit Quinquis, Kévin Da Silva, et al. "Benchmarking second and third-generation sequencing platforms for microbial metagenomics." Scientific Data 9, no. 1 (2022). http://dx.doi.org/10.1038/s41597-022-01762-z.

Der volle Inhalt der Quelle

Annotation:

AbstractShotgun metagenomic sequencing is a common approach for studying the taxonomic diversity and metabolic potential of complex microbial communities. Current methods primarily use second generation short read sequencing, yet advances in third generation long read technologies provide opportunities to overcome some of the limitations of short read sequencing. Here, we compared seven platforms, encompassing second generation sequencers (Illumina HiSeq 300, MGI DNBSEQ-G400 and DNBSEQ-T7, ThermoFisher Ion GeneStudio S5 and Ion Proton P1) and third generation sequencers (Oxford Nanopore Techno

APA, Harvard, Vancouver, ISO und andere Zitierweisen

26

Belova, Vera, Anna Shmitko, Anna Pavlova, et al. "Performance comparison of Agilent new SureSelect All Exon v8 probes with v7 probes for exome sequencing." BMC Genomics 23, no. 1 (2022). http://dx.doi.org/10.1186/s12864-022-08825-w.

Der volle Inhalt der Quelle

Annotation:

AbstractExome sequencing is becoming a routine in health care, because it increases the chance of pinpointing the genetic cause of an individual patient's condition and thus making an accurate diagnosis. It is important for facilities providing genetic services to keep track of changes in the technology of exome capture in order to maximize throughput while reducing cost per sample. In this study, we focused on comparing the newly released exome probe set Agilent SureSelect Human All Exon v8 and the previous probe set v7. In preparation for higher throughput of exome sequencing using the DNBSE

APA, Harvard, Vancouver, ISO und andere Zitierweisen

27

Suzuki, Akihiko, Masaki Kamakura, Takuya Shiramata, Shinji Nakaoka, and Yoshiko Sakamoto. "Comparison of RNA-Seq analysis data between tracheal mite-infested and uninfested Japanese honey bees (Apis cerana japonica)." BMC Research Notes 16, no. 1 (2023). http://dx.doi.org/10.1186/s13104-023-06381-4.

Der volle Inhalt der Quelle

Annotation:

Abstract Objective The purpose of this data set is to investigate differences in RNA-Seq transcriptome profiles between Acarapis woodi-infested and uninfested Japanese honey bees (Apis cerana japonica). The data set is strengthened by data collected from different body parts (head, thorax, and abdomen). The data set will support future studies of molecular biological changes in mite-infested honey bees. Data description We collected 5 mite-infested and 5 uninfested A. cerana japonica workers from each of 3 different colonies (designated as A, B, and C). Workers were dissected into 3 body sites

APA, Harvard, Vancouver, ISO und andere Zitierweisen

28

Koçak, Nadir, Ali Torabi, Batuhan Şanlıtürk, Ozkan Bagci, Ebru Marzioğlu-özdemir, and Tülin Çora. "Klinik Ekzom Sekans Trio Örneklerinde De Novo Mutasyonların Sıklığı ve Karakteristik Özlelliklerinin Araştırılması." Genel Tıp Dergisi, April 26, 2024. http://dx.doi.org/10.54005/geneltip.1463733.

Der volle Inhalt der Quelle

Annotation:

Özet Gelişmiş genom dizileme teknolojileri, genom ile ilişkilendirilen koşulların mekanizmalarını derinlemesine anlama fırsatı sunmuştur. Son zamanlarda, üreme hücrelerinde ortaya çıkan ve ebeveynlerde bulunmayan genetik değişiklikler olan de novo mutasyonların özelliklerini anlama konusunda önemli bir ilgi olmuştur ve oluşumlarına dahil olan mekanizmaları anlamak. Bu mutasyonlar sonraki nesillere aktarılabilir ve genetik çeşitliliği ve hastalıklara duyarlılığı etkileme potansiyeline sahiptir, bu nedenle bu konu önemlidir. Bu alandaki sınırlı çalışmalar nedeniyle, bu mutasyonların oluşum mekan

APA, Harvard, Vancouver, ISO und andere Zitierweisen

29

Ahmed, N., K. Beatson, J. Patel, M. Eddama, T. Abdel-Aziz, and L. Clapp. "75 CIRCULATING EXTRACELLULAR VESICLES AS DIAGNOSTIC BIOMARKERS FOR INDETERMINATE THYROID NODULES." British Journal of Surgery 111, Supplement_4 (2024). http://dx.doi.org/10.1093/bjs/znae104.014.

Der volle Inhalt der Quelle

Annotation:

Abstract Background Preoperative differentiation of benign from malignant indeterminate thyroid nodules (ITN) remains one of the most challenging issues in endocrine oncology. Most patients with an ITN will undergo diagnostic surgery with around 80% receiving a benign diagnosis on final histology. Liquid biopsy-based analysis of circulating extracellular vesicles (EVs) presents a promising diagnostic modality. The objective of this study is to measure the plasma levels of circulating EVs and identifying differentially expressed EV miRNAs in patients with benign versus malignant ITNs. Methods T

APA, Harvard, Vancouver, ISO und andere Zitierweisen

30

Cai, Ying, Ellis Anderson, Wen Xue, et al. "Assembly and analysis of the genome of Notholithocarpus densiflorus." G3: Genes, Genomes, Genetics, March 1, 2024. http://dx.doi.org/10.1093/g3journal/jkae043.

Der volle Inhalt der Quelle

Annotation:

Abstract Tanoak (Notholithocarpus densiflorus) is an evergreen tree in the Fagaceae family found in California and southern Oregon. Historically, tanoak acorns were an important food source for Native American tribes and the bark was used extensively in the leather tanning process. Long considered a disjunct relictual element of the Asian stone oaks (Lithocarpus spp.), phylogenetic analysis has determined that the tanoak is an example of convergent evolution. Tanoaks are deeply divergent from oaks (Quercus) of the Pacific Northwest and comprise a new genus with a single species. These trees ar

APA, Harvard, Vancouver, ISO und andere Zitierweisen

31

ALI, Azhin Saber, and Lana Sardar ALALEM. "Exploring the Diagnostic Potential of IHC and Next-Generation Sequencing Approaches for Endometrial Carcinoma Detection and Classification." Journal of Clinical Medicine: Current Research 3, no. 2 (2023). http://dx.doi.org/10.53043/2832-7551.jcmcr.3.008.

Der volle Inhalt der Quelle

Annotation:

Background: Globally, in 2018 endometrial cancer (EC) regarded as the sixth most commonly diagnosed cancer and the fourteenth leading cause of cancer with more deaths in females. Nowadays classical and modern classifications can be performing for diagnosing various types of cancers including endometrial cancer. Based on this our Objective of study is to determine the effectiveness of immunohistochemical observation, a quick and easy method for determining MSI and/or other types of EC which based on modern classification. As molecular study takes more cost we want to compare the both methods an

APA, Harvard, Vancouver, ISO und andere Zitierweisen

32

Milan, Paul Kubelac, Iulian Hotinceanu, Andreea Truican, et al. "Performance of a 52-gene NGS panel combined with shallow WGS for accurate HRD analysis." Journal of Clinical Oncology 43, no. 16_suppl (2025). https://doi.org/10.1200/jco.2025.43.16_suppl.e17570.

Der volle Inhalt der Quelle

Annotation:

e17570 Background: Homologous recombination deficiency (HRD) is a pivotal biomarker for predicting response to PARP inhibitors in multiple cancers. This study evaluates the analytical performance of a 53-gene somatic NGS panel combined with low-pass whole genome sequencing (shallow WGS, sWGS) for HRD assessment. Methods: In the present study, 36 FFPE tissues from ovarian cancer patients were analyzed for 52 genes implicated in DNA repair pathways, along with sWGS for the evaluation of tumor genomic instability (GI). Libraries were generated with the KAPA HyperPlus Kit (Roche) and sequenced in

APA, Harvard, Vancouver, ISO und andere Zitierweisen

33

Lima, Giscard, Alexander Kolliari-Turner, Fernanda Rossell Malinsky, et al. "Integrating Whole Blood Transcriptomic Collection Procedures Into the Current Anti-Doping Testing System, Including Long-Term Storage and Re-Testing of Anti-Doping Samples." Frontiers in Molecular Biosciences 8 (October 26, 2021). http://dx.doi.org/10.3389/fmolb.2021.728273.

Der volle Inhalt der Quelle

Annotation:

Introduction: Recombinant human erythropoietin (rHuEPO) administration studies involving transcriptomic approaches have demonstrated a gene expression signature that could aid blood doping detection. However, current anti-doping testing does not involve collecting whole blood into tubes with RNA preservative. This study investigated if whole blood in long-term storage and whole blood left over from standard hematological testing in short-term storage could be used for transcriptomic analysis despite lacking RNA preservation.Methods: Whole blood samples were collected from twelve and fourteen h

APA, Harvard, Vancouver, ISO und andere Zitierweisen

34

Zrelovs, Nikita, Gunta Resevica, Ieva Kalnciema, et al. "First report of black currant-associated rhabdovirus in blackcurrants in Latvia." Plant Disease, September 7, 2021. http://dx.doi.org/10.1094/pdis-06-21-1288-pdn.

Der volle Inhalt der Quelle

Annotation:

Blackcurrants (Ribes nigrum) are among the most important commercial berry crops in Latvia and, together with redcurrants and gooseberries, have a long history of local cultivation and breeding (Zuļģe et al. 2018). So far at least 20 viruses were reported to infect Ribes plants (Špak et al. 2021). Blackcurrant-associated rhabdovirus (BCaRV) was previously identified in USA by high throughput sequencing (HTS) of blackcurrant germplasm accession introduced from Russia (isolate Veloy) and now serves as an exemplar isolate for BCaRV (Wu et al. 2018). Presence of BCaRV was also confirmed by RT-PCR

APA, Harvard, Vancouver, ISO und andere Zitierweisen

35

Krog, M. C., N. Peker, L. W. Hugerth, et al. "O-262 The vaginal and faecal microbiome in women with recurrent pregnancy loss (RPL) before pregnancy according to the reproductive outcome after referral." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.316.

Der volle Inhalt der Quelle

Annotation:

Abstract Study question Is the vaginal or faecal microbiome different between primary RPL (pRPL) and secondary RPL (sRPL) patients, and is it related to reproductive outcome after referral? Summary answer Before pregnancy, the vaginal microbiome differed between pRPL and sRPL, and the faecal microbiome was altered in those who did not achieve pregnancy after follow-up. What is known already RPL is a heterogeneous condition leaving 50% of the couples without any known risk factors after the initial diagnostic workup. The microbiome of the reproductive tract seems to be an essential factor in wo

APA, Harvard, Vancouver, ISO und andere Zitierweisen

36

Handa, M., T. Takiuchi, T. Miyake, Y. Ando, J. W. Shin, and T. Kimura. "P-281 Single-cell RNA sequencing analysis of granulosa cells in preovulatory follicles in normal ovarian reserve patients undergoing progestin-primed ovarian stimulation and GnRH-antagonist." Human Reproduction 38, Supplement_1 (2023). http://dx.doi.org/10.1093/humrep/dead093.639.

Der volle Inhalt der Quelle

Annotation:

Abstract Study question Could the difference in controlled ovarian stimulation protocol between progestin-primed ovarian stimulation and GnRH-antagonist induce change in the expression genes of human granulosa cells? Summary answer The mitochondrial DNA (mtDNA) gene expression of granulosa cells in patients who underwent progestin-primed ovarian stimulation was significantly higher than the GnRH-antagonist. What is known already The progestin-primed ovarian stimulation (PPOS) protocol has attracted attention and many studies have reported similar pregnancy outcomes for both PPOS and the GnRH-a

APA, Harvard, Vancouver, ISO und andere Zitierweisen

37

Handa, M., T. Takiuchi, T. Miyake, Y. Ando, J. W. Shin, and T. Kimura. "P-549 Differentially expressed genes in the immune cells obtained from preovulatory follicles undergoing progestin-primed ovarian stimulation and GnRH-antagonist: Insights from single-cell RNA sequencing analysis." Human Reproduction 39, Supplement_1 (2024). http://dx.doi.org/10.1093/humrep/deae108.888.

Der volle Inhalt der Quelle

Annotation:

Abstract Study question Could controlled ovarian stimulation protocol (progestin-primed ovarian stimulation [PPOS] vs GnRH-antagonist [GnRH-ant]) affect the gene expression of human immune cells (ICs) in preovulatory follicles? Summary answer Proinflammatory cytokine-related gene expression was significantly higher and proinflammatory pathways were also more prominently involved in ICs in PPOS than the GnRH-ant. What is known already PPOS has garnered attention, with several studies suggesting reproductive outcomes comparable to GnRH-ant. However, in our previous study, pregnancy outcomes with

APA, Harvard, Vancouver, ISO und andere Zitierweisen

Wir bieten Rabatte auf alle Premium-Pläne für Autoren, deren Werke in thematische Literatursammlungen aufgenommen wurden. Kontaktieren Sie uns, um einen einzigartigen Promo-Code zu erhalten!