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Zeitschriftenartikel zum Thema "Endocrine system diseases – Drug therapy"

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Esin, O. R., A. I. Mashtakova, and R. G. Esin. "GABAergic system – physiological role and clinical significance." Meditsinskiy sovet = Medical Council, no. 3 (April 12, 2025): 118–26. https://doi.org/10.21518/ms2025-106.

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This work presents a review of the literature using the elibrary.ru, CyberLeninka, PubMed, Scopus and Google Scholar databases with the key terms “Gamma-aminobutyric acid (GABA)”, “GABA agonists”, “GABA antagonists”, “GABA pathophysiology”, “children and adolescents”. The information obtained was analyzed, systematized and presented in three sections: general aspects of GABA, pathophysiology of GABA and GABAergic pharmacology and therapy. Currently, three types of GABA receptors have been identified: two fast-acting GABA-A and GABA-C and one slow-acting GABA-B. GABA is a neurotransmitter and n
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Moon, Myung-Sang, Ki-Tae Kwon, Chang-Won Ha, Sung-Soo Kim, Sung Sim Kim, and Hanlim Moon. "BONE HISTOLOGY OF PATIENTS WITH ALENDRONATE-MEDIATED FRACTURED BONE — A NEW ENTITY OF ATYPICAL OSTEOMALACIA." Journal of Musculoskeletal Research 17, no. 03 (2014): 1450011. http://dx.doi.org/10.1142/s0218957714500110.

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Based on the pharmaco-physiology of the aminobisphosphonates, it could be speculated that bisphosphonates could induce not only the osteopetrotic bone disease because of their selective suppression of osteoclastic activity, but also could affect directly or indirectly the endocrine system, local factors, and also the bone metabolic turnover. Consequently, the bone fragility could be rather produced by long-term aminobisphosphonate therapy. Bisphosphonate-mediated bone disease was labeled by Odvina et al. in 2005 [Odvina CV, Zerwerth JE, Rao DS et al. Severely suppressed bone turnover; a potent
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Shih, Ming-Chi, Sergio Daniel Simon, Zhiming Jin, et al. "Efficient Synthesis of Glutamate Peptide-Estradiol Conjugate for Imaging Estrogen Receptor-Positive Diseases." BioMed Research International 2018 (September 25, 2018): 1–14. http://dx.doi.org/10.1155/2018/5208964.

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Molecular imaging of estrogen receptor-positive (ER+) pathway-activated system serves the basis of ER+ disease management such as cancers and endometriosis. ER+ patients have better response to endocrine therapy and survive twice as long as negative ER patients. However, tumor resistance resulting from clinical used aromatase inhibitors and antiestrogens is unpredictable. Radiolabeled ER+ ligand could quantify ER+ tissue uptake which helps to stage and restage of the cancer as well as endometriosis. The differential diagnosis of ER+ lesions by using a labeled ligand helps to select the patient
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Panova, Alexandra V., Daria V. Goliudsova, and Sergey L. Kiselev. "The prospect of pluripotent stem cells for diabetes mellitus treatment." World Journal of Personalized Medicine 1, no. 1 (2017): 13–17. http://dx.doi.org/10.14341/wjpm9297.

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Treatment options are limited for many diseases including diabetes, cancer and neurological and, many patients do not receive adequate therapy. New chemical entities largely developed within the BioPharma industry are not sufficient to satisfy patient’s needs. New gene and modified cell constructs were developed in academia and are expected on the market recently. This review presents describes somatic cells reprogramming technology and its application for the new drug development. We then summarize the progress made in genome editing and its application to cure monogenic hereditary disorders
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Orlyk, O. S., and A. V. Garnytska. "Endocrine side effects of immunotherapeutic drugs." Infusion & Chemotherapy, no. 3 (September 29, 2023): 43–48. http://dx.doi.org/10.32902/2663-0338-2023-3-43-48.

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BACKGROUND. Immunotherapy is an innovative approach to treatment that is changing the paradigm in oncology and is achieving significant results in the fight against malignant tumors including leukemia, melanoma, lung cancer, kidney cancer and many others. This treatment uses the power of the body’s immune system to fight cancer cells. Immunotherapy can lead to long-term remission or even complete disappearance of tumors in patients with certain types of cancer. The success of therapy depends on many factors, including the type of cancer and individual patient characteristics. As with any treat
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Palibrk, Ivan, Jelena Velickovic, Vesna Pantic-Palibrk, Vladimir Arsenijevic, Biljana Tanovic, and Djordje Ugrinovic. "Preoperative preparation for patients with nutritional disorders." Acta chirurgica Iugoslavica 58, no. 2 (2011): 163–68. http://dx.doi.org/10.2298/aci1102163p.

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Eating disorders are very common today. An increasing number of patients that undergo anesthesia and surgery have some nutritional disorder. These disorders are very versatile starting from obesity to anorexia. Significant changes in all organ systems are present. These pathophysiological changes are increased with the duration of the disease. There are many changes in the functioning of the cardiovascular system in all these diseases and there are significant. Respiratory and ventilatory functions are changed too. There are also many endocrine disorders. As a final result, there are many seri
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Verbovoy, A. F., and Yu A. Dolgikh. "Hypothyroidism in a physician’s practice: difficulties of diagnostics and treatment." Medical Council, no. 21 (January 28, 2020): 206–12. http://dx.doi.org/10.21518/2079-701x-2019-21-206-212.

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Hypothyroidism is the most common endocrine disease after diabetes mellitus. Its frequency depends on age, sex and iodine intake. The highest prevalence of hypothyroidism is observed in older women. Chronic autoimmune thyroiditis is the most common cause of this condition. The peculiarity of hypothyroidism is an erased clinical picture, diversity and nonspecific symptoms. This makes it difficult to diagnose the disease, leads to an erroneous diagnosis and later detection of thyroid insufficiency. This article discusses the various «masks» of hypothyroidism and peculiarities of clinical manifes
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Verbovoy, A. F., N. I. Verbovaya, and Yu A. Dolgikh. "Symbiosis of cardiology and endocrinology." Meditsinskiy sovet = Medical Council, no. 14 (October 15, 2020): 80–89. http://dx.doi.org/10.21518/2079-701x-2020-14-80-89.

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In medical practice, there are often patients who have several diseases at once, both pathogenetically related to each other and not related. The article discusses endocrine diseases in which there are manifestations from the cardiovascular system - disorders of carbohydrate metabolism, pathology of the thyroid gland, adrenal glands and acromegaly. These diseases reduce the quality of life of patients and increase the risks of cardiovascular complications. The article also discusses the features of cardiovascular manifestations in these diseases and indications for differential diagnosis. Type
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Zelinska, N. B., N. G. Rudenko, E. V. Globa, O. V. Rudenko, К. Grishchenko, and Y. S. Kavetska. "Diseases of the endocrine system in children in Ukraine and the provision of specialized care to pediatric patients in 2020." Ukrainian Journal of Pediatric Endocrinology, no. 2 (July 16, 2021): 4–14. http://dx.doi.org/10.30978/ujpe2021-2-4.

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The articles provide information and analysis of statistical indicators on the state of endocrinological care for children in 2020 in general in Ukraine and in some regions, their dynamics for 2014—2020. Providing data on staffing of the pediatric endocrinology service; the state of inpatient care for children with endocrine diseases; disability due to endocrine pathology, which has been carried out in recent years, is constantly growing, in particular diabetes, hypothyroidism and others; diseases and prevalence of malignant diseases of the endocrine glands in children. It is also possible to
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Sienicka, Agnieszka, Krzysztof Kubasik, and Agata Pisula. "The Glucagon-Like Peptide-1 Analogues therapy in the non-diabetic patients." Prospects in Pharmaceutical Sciences 21, no. 1 (2023): 9–14. http://dx.doi.org/10.56782/pps.127.

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Glucagon like peptide-1 (GLP-1) receptor agonists are a group of hypoglycemic drugs that are used primarily to treat type 2 diabetes both as monotherapy and in combination with other antidiabetic drugs. In contrast to most hypoglycemic drugs, GLP-1 receptor agonists not only do not cause weight gain, but can even lead to weight reduction. This is why they are recently also increasingly used in the treatment of obesity in patients without type 2 diabetes. Current research indicate that liraglutide and semaglutide are effective and safe methods of treatment for overweight and obesity in patients
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Dissertationen zum Thema "Endocrine system diseases – Drug therapy"

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Krause, Lauren Kendall. "Gene Expression patterns in High-Altitude Pulmonary Edema: A Gene Microway Analysis." Yale University, 2008. http://ymtdl.med.yale.edu/theses/available/etd-08152007-111828/.

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Multiple modulating genes and environmental factors have been implicated in the pathogenesis of high-altitude pulmonary edema (HAPE). However, at the present time, there exists an incomplete understanding of the molecular mechanisms and pathways which underlie constitutional susceptibility. Genome-wide measurements of gene expression in peripheral blood mononuclear cells (PBMCs) were performed using microarray technology. Comparison of gene expression profiles of HAPE-susceptible and resistant individuals resulted in the identification of several previously undescribed candidate genes. RhoA an
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Scisci, Nathália. "Prevalência e características da dor neuropática e neuropatia periférica em doentes submetidos à oxaliplatina para tratamento do câncer colorretal." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-24102016-152636/.

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Dor neuropática e neuropatia causadas pelo quimioterápico oxaliplatina são comuns e causam restrições às atividades funcionais e qualidade de vida. Muitos estudos têm quantificado e qualificado esses sintomas, porém raramente utilizando amostra expressiva e instrumentos validados e específicos para este fim. Neste estudo é proposta uma análise ampla, por instrumentos que quantificam e qualificam a dor e neuropatia relacionadas à oxaliplatina e suas características associadas. Objetivos: Identificar a prevalência de dor neuropática e neuropatia periférica em doentes com câncer colorretal recebe
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Tonezzer, Tania. "Uso da Estimulação Elétrica Nervosa Transcutânea (TENS) na redução dos sintomas de neuropatia periférica induzida por quimioterapia anti-neoplásica." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5170/tde-08032017-163417/.

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INTRODUÇÃO: A neuropatia periférica induzida por quimioterapia (NPIQ) está entre os efeitos colaterais mais comuns decorrentes da quimioterapia antineoplásica e uma das principais causas da redução da dose ou interrupção do tratamento. Os sintomas mais prevalentes são a dor e a parestesia, acarretando desconfortos crônicos e perda de habilidades funcionais, interferindo negativamente na qualidade de vida dos pacientes. Estudos recentes têm avaliado o uso da Estimulação Elétrica Nervosa Transcutânea (TENS) nesta patologia, apresentando evidências positivas na redução da dor, porém seu efeito no
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Smith, Jordan L. "Reversing Cancer Cell Fate: Driving Therapeutic Differentiation of Hepatoblastoma to Functional Hepatocyte-Like Cells." eScholarship@UMMS, 2020. https://escholarship.umassmed.edu/gsbs_diss/1067.

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Background & Aims: Despite advances in surgical care and chemotherapeutic regimens, the five-year survival rate for Stage IV Hepatoblastoma (HB), the predominant pediatric liver tumor, remains at 27%. YAP1 and β-Catenin co-activation occurs in 80% of children’s HB; however, a lack of conditional genetic models precludes exploration of tumor maintenance and therapeutic targets. Thus, the clinical need for a targeted therapy remains unmet. Given the predominance of YAP1 and β-catenin activation in children’s tumors, I sought to evaluate YAP1 as a therapeutic target in HB. Approach & Results: Her
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"Effects of menopause and menopausal hormone therapy on vascular reactivity in Hong Kong Chinese women." Thesis, 2006. http://library.cuhk.edu.hk/record=b6074199.

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Conclusion 1. The results of the research partly supported hypothesis 1a. There was a significant reduction in both endothelium-dependent arterial relaxation following a surgical menopause. The results of the research partly supported hypothesis 1b. There was a significant reduction in endothelium-dependent arterial relaxation but no significant effect on endothelium-independent arterial relaxation.<br>Conclusion 2. The results of the research partly supported hypothesis 2a. The addition of unopposed oestrogen significantly improved endothelium-dependent but not endothelium-independent arteria
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"Effect of phytoestrogens on low-density- lipoprotein receptor and apolipoprotein A-I expression in HepG2 cells." 2005. http://library.cuhk.edu.hk/record=b5896408.

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Yuen Yee Man.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2005.<br>Includes bibliographical references (leaves 108-125).<br>Abstracts in English and Chinese.<br>TITLE PAGE --- p.1<br>ACKNOWLEGDEMENTS --- p.2<br>ABSTRACT --- p.3<br>摘要 --- p.5<br>table of contents --- p.7<br>list of figures and tables --- p.13<br>CHAPTER 1 GENERAL INTRODUCTION --- p.16<br>Chapter 1.1 --- role of PHYTOESTROGENS in soy and red WINE the PREVENTION OF CARDIOVASCULAR DISEASES (CVD) --- p.17<br>Chapter 1.1.1 --- INTRoduction and Classification of Phytoestrogens --- p.17<br>Chapter 1.1.2 --- estrogen
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"The impact of selective COX-2 inhibitor on the cost of NSAID-induced gastrointestinal toxicity in a public hospital setting in Hong Kong." 2005. http://library.cuhk.edu.hk/record=b5892477.

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Ho Toi Sze Joyce.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2005.<br>Includes bibliographical references (leaves 65-74).<br>Abstracts in English and Chinese.<br>Acknowledgement --- p.ii<br>Contents --- p.iii<br>Abstract --- p.viii<br>List of Abbreviations --- p.xvii<br>List of Tables --- p.xix<br>List of Figures --- p.xx<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- The role of Non-steroidal anti-inflammatory drugs (NSAIDs) --- p.1<br>Chapter 1.2 --- NSAID-induced gastrointestinal (GI) toxicity --- p.1<br>Chapter 1.2.1 --- Pathogenesis of NSAID-induced G
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Bücher zum Thema "Endocrine system diseases – Drug therapy"

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Wayne, Meikle A., ed. Endocrine replacement therapy in clinical practice. Humana Press, 2003.

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Jean, Ginsburg, and Prelević Gordana M, eds. Drug therapy in reproductive endocrinology. Arnold, 1996.

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Milne, George W. A., 1937-, ed. Ashgate handbook of endocrine system agents and steroids. Ashgate, 2000.

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Wayne, Meikle A., ed. Hormone replacement therapy. Humana Press, 1999.

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S, Avery Graeme, and Speight Trevor M. ed, eds. Drug treatment: Principles and practice of clinical pharmacology and therapeutics. 3rd ed. Williams & Wilkins, 1987.

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L, Tan S., and Tulandi T, eds. Reproductive endocrinology and infertility: Current trends and developments. Marcel Dekker, 2003.

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M, Hall George. Core topics in endocrinology in anaesthesia and critical care. Cambridge University Press, 2010.

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F, Crass M., and Avioli Louis V, eds. Calcium-regulating hormones and cardiovascular function. CRC Press, 1995.

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1933-, Thomas J. A., Korach Kenneth S, and McLachlan John A, eds. Endocrine toxicology. Raven Press, 1985.

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1934-, Bardin C. Wayne, ed. Current therapy in endocrinology and metabolism--3. 3rd ed. B.C. Decker, 1988.

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Buchteile zum Thema "Endocrine system diseases – Drug therapy"

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Bos, Jan D. "Skin immune system (SIS)." In Immunology and Drug Therapy of Allergic Skin Diseases. Birkhäuser Basel, 2000. http://dx.doi.org/10.1007/978-3-0348-8464-8_1.

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Buchanan, W. W., and P. M. Brooks. "Prediction of organ system toxicity with antirheumatic drug therapy." In Prognosis in the Rheumatic Diseases. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3896-3_18.

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Maruyama, Wakako, and Makoto Naoi. "Application of the Multi-Electrode Detection System to the Monitoring of Drug Therapy in Neurological Diseases." In Coulometric Electrode Array Detectors for HPLC. CRC Press, 2024. http://dx.doi.org/10.1201/9780429070303-12.

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Duzova, Mursel. "Ensuring Functional Recovery After Radiothrapy." In Oncological Rehabilitation a Handbook for Healthcare Professionals. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358893.3.

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Radiotherapy, a cornerstone of cancer treatment, often leads to significant side effects that can impair a patient’s functional abilities and quality of life. This chapter explores the critical role of rehabilitation in mitigating these side effects and ensuring functional recovery and maintenance across various cancer types. Radiotherapy can cause a range of complications, including tissue fibrosis, muscle weakness, lymphedema, and cognitive deficits, necessitating a comprehensive rehabilitation approach. We begin by highlighting the necessity of rehabilitation for patients undergoing head an
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Telang, Nitin. "Stem Cell Models: Novel Experimental Approach for Testable Alternatives against Therapy-resistant Breast and Colon Cancer." In Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815179217123010018.

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Breast and colon cancer represent the leading causes of mortality in developed countries. The treatment options for these organ site cancers differ depending on the status of hormone/growth factor receptors in molecular subtypes that exhibit altered expression of oncogenes/tumor suppressor genes and growth factormediated molecular pathways. Conventional cytotoxic chemo-endocrine therapy traditionally includes the use of anthracyclin, taxol, cisplatin, anti-estrogens, antifolates and DNA anti-metabolites. Additionally, the use of molecular pathway-specific small molecule inhibitors represents e
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Reddy, Bhavanam Sudhakara, Sirigireddy Sivajothi, and Kambala Swetha. "Prevention and Control Strategy." In Common Ear Diseases in Dogs: Diagnosis and Management. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815313598125010026.

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Ear diseases are considered as one of the common disorders in small animal practice and the number one cause for veterinary visits among dog owners. Commonly reported clinical signs in dogs with ear disease were scratching or pawing at the ear, otitis, head tilting, head shaking, strong and unpleasant odour from the ears, abnormal ear discharges and pain evincing while palpation of ears. These ear infections can cause significant discomfort to the dogs as well as occurrence of recurrence. The first step in the control and prevention of ear infections is to identify the primary and/ or perpetua
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Richards, Duncan, Jeffrey Aronson, D. John Reynolds, and Jamie Coleman. "Endocrine system; obstetrics and gynaecology." In Oxford Handbook of Practical Drug Therapy. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199562855.003.0194.

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LØnning, Per Eystein. "Anti-endocrine drugs used in cancer treatment." In Cancer Clinical Pharmacology. Oxford University PressNew York, NY, 2005. http://dx.doi.org/10.1093/oso/9780192629661.003.0015.

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Abstract The discovery by Beatson a century ago that castration may cause tumour regression in premenopausal breast cancer patients marks endocrine therapy as the first successful systemic treatment strategy for malignant diseases. Although other forms of ablative surgery (orchiectomy in males suffering from prostatic carcinomas, and adrenalectomy and hypophysectomy in postmenopausal breast cancer patients) and, in the 1950s and 1960s, additive treatment with oestrogens or glucocorticoids came into
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Duncan, Richards, and Jeffrey Aronson. "Chapter 6 Endocrine system; obstetrics and gynaecology." In Oxford Handbook of Practical Drug Therapy. Oxford University Press, 2005. http://dx.doi.org/10.1093/med/9780198530077.003.0006.

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Gupta, Dr Surya Prakash. "Endocrine System." In Edited Book of Pathophysiology. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/nbennurebch10.

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The endocrine system is essential for regulating various physiological processes through hormone secretion. Disorders in this system, such as diabetes, thyroid diseases, and sex hormone imbalances, can have significant health impacts. Diabetes mellitus is a chronic condition characterized by high blood glucose levels due to insulin deficiency (Type 1) or insulin resistance (Type 2). The pathophysiology involves autoimmune destruction of pancreatic beta cells in Type 1 diabetes and insulin resistance with progressive beta-cell dysfunction in Type 2. Epidemiologically, diabetes is a global epide
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Konferenzberichte zum Thema "Endocrine system diseases – Drug therapy"

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Okun', Dmitriy. "FORMAL REPRESENTATION OF KNOWLEDGE ABOUT MEDICAMENTAL THERAPY FOR ISCHEMIC HEART DISEASES (detail)." In XIV International Scientific Conference "System Analysis in Medicine". Far Eastern Scientific Center of Physiology and Pathology of Respiration, 2020. http://dx.doi.org/10.12737/conferencearticle_5fe01d9bce39f8.78028503.

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The paper describes a fragment of the knowledge base of drug therapy for ischemic heart disease, hosted on the IACPaaS platform. Generally accepted medical terminology is used in the formation of knowledge.
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ХИЗРИЕВ, М. Д., И. Э. АТАШЕВА, and З. О. ГАРУНОВ. "Drug therapy of patients with stable angina pectoris." In II Международная научно-практическая конференция "Преобразование современного мира: проблемы и возможности". Crossref, 2024. http://dx.doi.org/10.26118/5186.2024.80.69.007.

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Одной из значимых проблем, которые продолжают убивать людей в мировой медицинской практике, являются заболевания системы кровообращения, несмотря на постоянное совершенствование методов лечения. В 2016 году сердечно-сосудистыми заболеваниями страдали, согласно отчету Всемирной организации здравоохранения, 17,9 млн человек, и это составило 85% всех случаев, связанных с инфарктами и инсультами, закончившимися летально [1]. По данным за 2020 год, в Российской Федерации 938 536 смертей вызваны болезнями системы кровообращения, из них 54,2% приходится на ишемическую болезнь сердца. Основными фактор
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Filipović, Nenad. "Applied artificial intelligence in diagnostics and therapy of cardiovascular diseases." In Veštacka inteligencija - prakticna primena i izazovi. Savez inženjera i tehničara Srbije, 2024. https://doi.org/10.5937/vi24043f.

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The use of a computational platform can reduce costs and time required for developing new models of medical devices and drugs. EU project STRATIFYHF is to develop and clinically validate a truly innovative AI-based Decision Support System for predicting the risk of heart failure, facilitating its early diagnosis and progression prediction that will radically change how heart failure is managed in both primary and secondary care. It is developed using state-of-the-art finite element modelling for macro simulation of fluid-structure interaction with micro modelling at the molecular level for dru
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Sheenkova, M. V. "ON THE PATHOGENESIS OF GASTRODUODENAL ZONE LESIONS IN VARIOUS VARIANTS OF DRUG THERAPY FOR OCCUPATIONAL RESPIRATORY DISEASES." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-575-578.

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Abstract. A survey of workers of large industrial enterprises with occupational diseases of the respiratory system was conducted to assess the dependence of the risk of damage to the upper gastrointestinal tract on the features of pharmacological therapy of respiratory pathology. The specificity of the pathogenesis of gastric and duodenal lesions associated with the properties of drug treatment of occupational respiratory diseases was revealed.
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Smirnykh, D. V., E. S. Sushko, A. G. Kicheeva, and N. S. Kudryasheva. "THE EFFECT OF METAL-ORGANIC FRAMEWORKS FUNCTIONALIZED WITH MAGNETITE ON THE BIOLUMINESCENT ENZYMATIC ASSAY SYSTEM." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-214.

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The inhibitory ability of three iron-containing coordination polymers (MOF, Fe3 O4 -MОF and MОF-Fe3 O4 ) was analyzed using a bioluminescent enzymatic assay. The results showed the neutrality of all coordination polymers and a low ROS content of non-functional polymers. Safe operation of these polymers for local drug delivery in therapy of oncological diseases is assumed.
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Dahmen, Christian, Tim Wortmann, and Sergej Fatikow. "Magnetic Resonance Imaging of Magnetic Particles for Targeted Drug Delivery." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13149.

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Recently there have been initial investigations towards magnetic resonance imaging (MRI) guided actuation and control of untethered devices inside the human cardiovascular system. This form of therapy has the potential to revolutionize today’s treatment of cancer and other diseases by providing an accuracy of targeted drug application far beyond conventional approaches. Additionally it is based on standard MRI hardware and does not require any special or tailored hardware. In this article, we present recent work that is focused on visual feedback for the position control of untethered magnetic
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Pogodaeva, P. S. "Changes in the biochemical parameters of the blood of rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-11-35-40.

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An interesting and unexplored to date is the hepatoprotective effect of hypoglycemic drugs, analogues of glucagon-like peptide-1, which include liraglutide. Knowing the positive effect of liraglutide on plasma lipid fractions and a general decrease in adipose tissue, a decrease in glucagon production and an increase in insulin synthesis, a beneficial effect on the cardiovascular system and an anti-inflammatory effect, there is reason to believe that this drug may be useful in the complex therapy of liver diseases, such as fatty hepatosis, cirrhosis and non-infectious hepatitis, as its action a
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Marković, Maja. "Controlled release of caffeine from three dimensional networks based on poly(metacrylic acid) and casein - analysis of the effect of caffeine concentration on release process." In 35th International Congress on Process Industry. SMEITS, 2022. http://dx.doi.org/10.24094/ptk.022.019.

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Everyday demands for safer and more efficient therapy for many diseases, especially serious ones such as various types of cancer, put various challenges in front of modern science. One of them lies in the fact that numerous anticancer drugs are poorly-water soluble and therefore their encapsulation and controlled release are quite demanding processes. In the present study, we deepened our research of carrier based on hydrophilic poly(methacrylic acid) modified with amphiphilic casein, in which poorly water-soluble model drug caffeine was encapsulated (PMAC-Caf hydrogels). It was investigated h
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Andrade, Dariana Rodrigues, Letícia Mendes de Lima, Luis Henrique Goes Hamati Rosa, and Edvaldo Cardoso. "Brain-gut-microbiota axis in motor disorders." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.401.

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Introduction: There seems to be a strong relationship and influence on the brain-gut- microbiota axis in the control and prevention of several diseases, including degenerative diseases that are related to motor disorders. Objectives: To analyze the relationship between movement disorders and the intestinal microbiota. Methods: Integrative review performed at PUBMED, using the descriptors Movement disorder and intestinal microbiota, in the last five years and having as inclusion criteria complete texts in English. Results: The literature suggests that the intestinal microbiota regulates the act
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Berichte der Organisationen zum Thema "Endocrine system diseases – Drug therapy"

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Grueso-Navarro, Elena, Leticia Rodríguez-Alcolado, Ángel Arias, Emilio J. Laserna-Mendieta та Alfredo J. Lucendo. Influence of HLA-DQA1*05 allele in the response to anti-TNFα drugs in inflammatory bowel diseases. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0076.

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Review question / Objective: Do patients with inflammatory bowel disease and treated with any anti-TNFα drug who had the HLA-DQA1*05 allele (in heterozygosis or homozygosis) have lower response or persistence to those drugs than patients without HLA-DQA1*05 allele? Condition being studied: Inflammatory bowel diseases (IBD), which includes Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory condition that may affect any part of the digestive tract (CD) or be limited to the colon (UC). While the specific aetiology of IBD remains unknown, it is believed to involve a comple
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