Thematische Bibliographien / Functionnal genes

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Auswahl der wissenschaftlichen Literatur zum Thema „Functionnal genes“

Autor: Grafiati

Veröffentlicht am 11. Januar 2025

Zuletzt aktualisiert am 31. Juli 2025

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Zeitschriftenartikel zum Thema "Functionnal genes"

Sitnicka, Dorota, Katarzyna Figurska, and Slawomir Orzechowski. "Functional Analysis of Genes." Advances in Cell Biology 2, no. 1 (2010): 1–16. http://dx.doi.org/10.2478/v10052-010-0001-y.

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SummaryThe aim of this article is to present the current literature concerning the expression analysis and methods of functional characteristics of genes. The progress in the analysis of gene expression within cells or whole tissues is undisputed and leads to a constant improvement of our understanding of the function of particular gene. The traditional methods of the functional characteristics of genes such as homology, inactivation and overexpression are more frequently being replaced by microarray and DNA chip analysis, which are extensively supported by bioinformatics tools. Knowledge of t

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Jeong, Soon-Seog, and Ridong Chen. "Functional misassignment of genes." Nature Biotechnology 19, no. 2 (2001): 95. http://dx.doi.org/10.1038/84480.

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Scott, Rodney J. "Cancer genes: Functional aspects." European Journal of Cancer 33, no. 10 (1997): 1706–7. http://dx.doi.org/10.1016/s0959-8049(97)00259-1.

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Carpenter, D., R. S. McIntosh, R. J. Pleass, and J. A. L. Armour. "Functional effects of CCL3L1 copy number." Genes & Immunity 13, no. 5 (2012): 374–79. http://dx.doi.org/10.1038/gene.2012.5.

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Klee, Eric W., Stephen C. Ekker, and Lynda B. M. Ellis. "Target selection forDanio rerio functional genomics." genesis 30, no. 3 (2001): 123–25. http://dx.doi.org/10.1002/gene.1045.

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Montgomery, Nathan D. "Functional genomics: A rose by another name." genesis 33, no. 3 (2002): 140. http://dx.doi.org/10.1002/gene.10101.

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ABDULAZIZ, ABDUJABAR, and GURJA BELAY Dr. "A Review on Molecular and Cellular Basis of Plant-Parasitic Root Knot Nematode-Host Interactions: Host Resistance." International Journal of Recent Research in Life Sciences 9, no. 2 (2022): 46–63. https://doi.org/10.5281/zenodo.6527409.

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<strong>Abstracts:</strong> Root‐knot nematodes (RKN), (<em>Meloidogyne</em> spp.) are obligate endoparasites of more than 3000 species of plants, which results in $70 billion worth of economic loss every year, worldwide. Controlling of obligated plant parasitic rootknot-nematode is generally difficult and also with the banning of many nematicides chemicals that control nematode, because of adverse environmental impacts, it is recommended to develop host resistance genes. Although, many R-gene confer resistance to RKN have been identified, the majority of these gene lose durability o

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Purnell, Beverly A. "Functional screen for microcephaly genes." Science 370, no. 6519 (2020): 926.3–926. http://dx.doi.org/10.1126/science.370.6519.926-c.

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Camilleri, M., and A. R. Zinsmeister. "Candidate genes and functional dyspepsia." Neurogastroenterology & Motility 21, no. 1 (2009): 94. http://dx.doi.org/10.1111/j.1365-2982.2008.01205.x.

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Oliveira, Daniela M., and Margaret A. Goodell. "Transient RNA interference in hematopoietic progenitors with functional consequences." genesis 36, no. 4 (2003): 203–8. http://dx.doi.org/10.1002/gene.10212.

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Dissertationen zum Thema "Functionnal genes"

Heglind, Mikael. "Functional studies of two forkhead genes /." Göteborg : Institute of Biomedicine, Department of Medical and Clinical Genetics, The Sahlgrenska Academy at University of Gothenburg, 2010. http://hdl.handle.net/2077/21481.

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Rice, Kim. "Functional analysis of the HOX11 target genes ALDH1A1 and FHL1." Thesis, Rice, Kim (2004) Functional analysis of the HOX11 target genes ALDH1A1 and FHL1. PhD thesis, Murdoch University, 2004. https://researchrepository.murdoch.edu.au/id/eprint/277/.

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HOX11 is a developmental regulator that plays a crucial role in the normal development of the spleen and is also aberrantly activated by the t(10;14)(q24;q11) and variant t(7;10)(q35;q24) translocations in a subset of T-cell acute lymphoblastic leukaemias (TALLs). The recent finding that HOX11 is deregulated in up to 40% of childhood TALLs when abnormalities not detected by cytogenetics are included, suggests that the over-expression of HOX11 and subsequent deregulation of downstream target genes are critical events in the progression of this tumour type. To date, three candidate HOX11 target

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Rice, Kim. "Functional analysis of the HOX11 target genes ALDH1A1 and FHL1 /." Access via Murdoch University Digital Theses Project, 2004. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20051012.93820.

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Fernandes, Alinda. "Lentiviral-mediated gene delivery to investigate the functional role of neuropsychiatric genes." Thesis, King's College London (University of London), 2013. https://kclpure.kcl.ac.uk/portal/en/theses/lentiviralmediated-gene-delivery-to-investigate-the-functional-role-of-neuropsychiatric-genes(b6392e47-e94b-4e64-b343-e7eafd696b26).html.

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Genetic studies have led to the identification of several candidate genes, some novel and others established, that may contribute to the risk of developing neuropsychiatric disorders. For example, dopamine receptor genes are established candidates for a number of psychiatric disorders such as Parkinson’s Disease, alcohol addiction and mood disorders. On the other hand, a gene of unknown function, AUTS2 (Autism susceptibility candidate 2), has recently been associated with alcohol consumption in a GWAS meta-analysis performed by our group. Interestingly, it has been associated with a broad rang

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Kacar, Betül, Eva Garmendia, Nurcan Tuncbag, Dan I. Andersson, and Diarmaid Hughes. "Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs." AMER SOC MICROBIOLOGY, 2017. http://hdl.handle.net/10150/625744.

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Genes encoding proteins that carry out essential informational tasks in the cell, in particular where multiple interaction partners are involved, are less likely to be transferable to a foreign organism. Here, we investigated the constraints on transfer of a gene encoding a highly conserved informational protein, translation elongation factor Tu (EF-Tu), by systematically replacing the endogenous tufA gene in the Escherichia coli genome with its extant and ancestral homologs. The extant homologs represented tuf variants from both near and distant homologous organisms. The ancestral homologs re

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Fan, Li. "Map based candidate gene cloning and functional analysis of genes involved in VLCFAs synthesis." [Ames, Iowa : Iowa State University], 2007.

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Ashwood, Lauren M. "Characterising the functional venom profiles of sea anemones." Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/227457/1/Lauren_Ashwood_Thesis.pdf.

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This project examined the relationship between the ecological roles of venom and patterns of venom production in sea anemones. It was found that sea anemones produce multiple venoms and that these distinct venoms are associated with the ecological functions of envenomating structures. Overall, this information provides insights into the ecological context of venom regulation and provides a rational framework for pharmaceutical bioprospecting in sea anemones.

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Kolle, Gabriel Victor. "Functional analysis of vertebrate Crim1 /." [St. Lucia, Qld.], 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16804.pdf.

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Couldrey, Christine. "A gene trap approach to identify the functional role of genes expressed during murine gametogenesis." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624246.

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Tronnersjö, Susanna. "Functional studies of RNA polymerase II-dependent transcription in yeast Saccharomyces cerevisiae /." Uppsala : Department of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/2006109.pdf.

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Bücher zum Thema "Functionnal genes"

Enrico, Mihich, Housman David E, and Pezcoller Symposium on Cancer Genes: Functional Aspects (7th. : 1995 : Trento, Italy), eds. Cancer genes: Functional aspects. Plenum Press, 1996.

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Smoler, Gunilla Kanter. Functional characterisation of conserved checkpoint genes. [s.n.], 1998.

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Schumann, Wolfgang, Prof. Dr. rer. nat., Ehrlich S. Dusko, and Ogasawara Naotake, eds. Functional analysis of bacterial genes: A practical manual. J. Wiley, 2001.

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Alonso, Jose M., and Anna N. Stepanova. Plant functional genomics: Methods and protocols. Humana Press, 2015.

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Erjavec, Stephanie O'Toole. Utilizing functional genomics approaches to characterize risk genes in alopecia areata. [publisher not identified], 2020.

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Roepke, Jonathon. Localization and functional characterization of iridoid biosynthetic genes in Catharanthus roseus. Brock University, Centre for Biotechnology, 2008.

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Berkowitz, Noah C. Functional importance of polymorphic subregions in the C3H anti I-Ab alloresponse. [Columbia University], 1993.

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Erich, Grotewold, ed. Plant functional genomics. Humana Press, 2003.

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Wuke. cDNA cloning, sequence analysis, and expression studies of the murine Hox-1.7 and Hox-1.8 homeobox genes and functional studies of the murine Hox-1.4 homeobox gene. Columbia University, 1992.

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Issar, Smith, Slepecky Ralph, Setlow Peter, and International Spore Conference, (10th : 1988 : Woods Hole, Mass.), eds. Regulation of procaryotic development: A structural and functional analysis of bacterial sporulation and germination. American Society for Microbiology, 1989.

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Buchteile zum Thema "Functionnal genes"

Andleeb, Tayyaba, James Milson, and Philippa Borrill. "The Wheat Transcriptome and Discovery of Functional Gene Networks." In Compendium of Plant Genomes. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-38294-9_5.

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AbstractGene expression patterns have been a widely applied source of information to start understanding gene function in multiple plant species. In wheat, the advent of increasingly accurate and complete gene annotations now enables transcriptomic studies to be carried out on a routine basis and studies by groups around the world have compared gene expression changes under an array of environmental and developmental stages. However, associating data from differentially expressed genes to understanding the biological role of these genes and their applications for breeding is a major challenge.

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Ng, Esther Feng Ying, and Franz Meitinger. "Genetic Engineering and Screening Using Base Editing and Inducible Gene Knockout." In Methods in Molecular Biology. Springer US, 2024. https://doi.org/10.1007/978-1-0716-4224-5_12.

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AbstractGenetic engineering and screening in human cells are powerful techniques for the precise and comprehensive identification and analysis of gene and protein domain functions. Genome-wide knockout screens have been extensively utilized to discover essential genes, tumor suppressors, and genes that regulate responses to various chemicals, including antimitotic and therapeutic drugs. The advent of base editors, which facilitate the targeted mutation of single amino acids, has advanced the identification of critical and functional domains or motifs. In this context, we outline methods for cr

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Rasheed, Awais, Humaira Qayyum, and Rudi Appels. "Genome-Informed Discovery of Genes and Framework of Functional Genes in Wheat." In Compendium of Plant Genomes. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-38294-9_9.

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AbstractThe complete reference genome of wheat was released in 2018 (IWGSC in Science 361:eaar7191, 2018), and since then many wheats genomic resources have been developed in a short period of time. These resources include resequencing of several hundred wheat varieties, exome capture from thousands of wheat germplasm lines, large-scale RNAseq studies, and complete genome sequences with de novo assemblies of 17 important cultivars. These genomic resources provide impetus for accelerated gene discovery and manipulation of genes for genetic improvement in wheat. The groundwork for this prospect

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Guo, Hui-jun, Yong-dun Xie, Lin-shu Zhao, et al. "Progress of mutant resource development and tilling on starch biosynthesis in wheat." In Mutation breeding, genetic diversity and crop adaptation to climate change. CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0028.

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Abstract Induced mutations have been widely utilized for the development of plant mutant germplasm and varieties since 1927 and have contributed to genetic diversity enhancement and food security in the world. Mutant resources are essential for gene identification and functional characterization by forward and reverse genetic strategies. The publishing of annotated wheat reference genomes is greatly promoting the progress of wheat functional genomic research. Mutant resources of a broad spectrum and diversified wild- types will be the prerequisites in this process, in part due to the polyploid

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Murphy, P. J., A. Karakousis, S. E. Smith, and P. Langridge. "Cloning Functional Endomycorrhiza Genes." In Biotechnology of Ectomycorrhizae. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1889-1_7.

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Zhegunov, Gennadiy. "Functional Systems of Genes." In The Dual Nature of Life. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-30394-4_23.

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Makino, Takashi, David G. Knowles, and Aoife McLysaght. "Functional Divergence of Duplicated Genes." In Evolution after Gene Duplication. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9780470619902.ch2.

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Caskey, C. T., Q. Liu, M. L. Metzker, D. Gerhold, and C. P. Austin. "Functional Analysis of Human Genes." In Genomics: commercial opportunities from a scientific revolution. Garland Science, 2023. http://dx.doi.org/10.1201/9781003423782-7.

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Xu, Ying. "Computational Methods for Functional Prediction of Genes." In Microbial Functional Genomics. John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471647527.ch5.

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Bhalla, Parinishtha, Anukriti Verma, Bhawna Rathi, Shivani Sharda, and Pallavi Somvanshi. "Exploring Molecular Signatures in Spondyloarthritis: A Step Towards Early Diagnosis." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_15.

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AbstractSpondyloarthritis is an acute inflammatory disorder of the musculoskeletal system often accompanied by pain, stiffness, bone and tissue damage. It majorly consists of ankylosing spondylitis, psoriatic arthritis and reactive arthritis. It follows a differential diagnosis pattern for demarcation between the spondyloarthritis subtypes and other arthritic subtypes such as rheumatoid arthritis, juvenile arthritis and osteoarthritis due to the heterogeneity causing gradual chronicity and complications. Presence of definite molecular markers can not only improve diagnosis efficiency but also

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Konferenzberichte zum Thema "Functionnal genes"

Zhu, Xiang Y., Alvin Ayala, Hetal Modi, and John J. Kilbane. "Application of Quantitative, Real-Time PCR in Monitoring Microbiologically-Influenced Corrosion (MIC) in Gas Pipelines." In CORROSION 2005. NACE International, 2005. https://doi.org/10.5006/c2005-05493.

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Abstract Quantitative PCR (qPCR) methods (fluorogenic 5′-nuclease assay and SYBR Green I assay) were developed to detect and quantify bacteria and some critical sub-populations related to gas and oil pipeline corrosion. 16S rRNA genes were targeted for the detection and quantification of total bacteria using fluorogenic 5′-nuclease assays. The functional genes, dissimilatory sulfite reductase gene (dsrAB), nitrite reductase gene (nirS), and methyl-coenzyme M reductase gene (mcrA), were targeted for sulfate reducing bacteria (SRB), denitrifying bacteria, and methanognes, respectively. The metho

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Otte, Lennart B., Christer Hogstrand, Adil Mardinoglu, and Miao Guo. "Multi-Omics biological embeddings for ML-models." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.136974.

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Machine learning algorithms have led to the development of numerous vector embeddings for biological entities such as metabolites, proteins, genes, and enzymes. However, these embeddings often lack contextual information due to their specialized focus on individual omics. Disease progression and biosynthesis pathways are increasingly understood through complex, multi-layered networks that integrate diverse omics data and intricate signaling and reaction sequences. Capturing these relationships in a meaningful way requires embeddings that account for both functional and multi-modal dependencies

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Fida, Tekle, Luke Austin, Scott Leleika, Taylor Rambo, and Karen Crippen. "Development of Molecular Probe for Iron Reducing and Thiosulfate Reducing Bacteria." In CONFERENCE 2024. AMPP, 2024. https://doi.org/10.5006/c2024-20885.

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Abstract Microbiologically Influenced Corrosion (MIC) activities are mostly monitored by using canonical culture-based methods. However, these methods detect only culturable bacteria or require months of incubation to get results. To overcome this, molecular detection methods were developed for many of the MIC-causing microbes but were not available for Iron Reducing Bacteria (IRB) and Thiosulfate Reducing Bacteria (TRB). IRB and TRB are among the dominant group of microbes involved in corrosion and souring oil and gas infrastructures. In the present study, molecular probes were developed for

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Coorey, H., R. Jayatillaka, N. Jayathilaka, and N. Ambanpola. "Determining Differentially Expressed Genes in Dengue Patients during Disease Progression." In SLIIT International Conference on Advancements in Sciences and Humanities 2023. Faculty of Humanities and Sciences, SLIIT, 2023. http://dx.doi.org/10.54389/ajrm6708.

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Gene expression studies on gene transcription to synthesize functional gene products have been used extensively to understand the biological differences between different disease conditions. Thus, this study determines differentially expressed genes in dengue infection during disease progression following the three phases: Febrile, Defervescence and Convalescent. Integrative data analysis of two publicly available longitudinal datasets in the Gene Expression Omnibus (GEO) database has been employed to accomplish the prime objective of exploring temporal gene expression patterns. The Friedman t

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Malyutina, T. A. "NEUROPEPTIDES INVOLVING IN THE REGULATION OF LOCOMOTOR BEHAVIOR OF ROOT-KNOT PLANT-PARASITIC NEMATODES (REVIEW)." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.281-284.

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In the last few decades, the attention of researchers has been attracted by endogenous FMRFamide-like neuropeptides found in a number of invertebrates, including species of the Nematoda phylum. A foreign literature review was presented for the functional significance of endogenous FMRFamide-like neuropeptides in locomotor behaviour of root-knot phytonematodes, representatives of the genus Meloidogyne Goldi, 1982, namely, Meloidogyne incognita, M. minor, M. hapla and M. graminicola. In Russia, such studies are not carried out. The main characteristics o

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Uvarova, A. N., E. A. Tkachenko, K. V. Korneev, and D. V. Kuprash. "FUNCTIONAL ANALYSIS OF SNPS ASSOCIATED WITH SEVERE VIRAL RESPIRATORY DISEASES AND LOCATED IN THE REGULATORY REGIONS OF ANTIVIRAL IMMUNE RESPONSE GENES." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-378.

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We investigated the regulatory regions of the CD55, LGALS1, and IFNAR2 genes in cell models of human macrophages and B-cells and analyzed several SNPs located in the regulatory regions of these genes and associated with severe COVID-19 or flu. In the course of this work, we characterized the IFNAR2 gene enhancer and performed functional annotation of several SNPs in the CD55 and LGALS1 promoters.

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Ploos van Amstel, J. K., A. L. van der Zanden, P. H. Reitsma, and R. M. Bertina. "RESTRICTION ANALYSIS AND SOUTHERN BLOTTING OF TOTAL HUMAN DNA REVEALS THE EXISTENCE OF MORE THAN ONE GENE HOMOLOGOUS WITH PROTEIN S cDNA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644639.

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A deficiency in protein S, the cofactor of activated protein C, is associated with an increased risk for the development of venous thrombosis. It is inherited as an autosomal dominant disorder. To improve the detection of heterozygotes in affected families, we have started to search for restriction fragment length polymorphism (RFLP) in the protein S gene. This study revealed the existence of two genes containing sequences homologous to protein S cDNA.Three non-overlapping fragments of clone pSUL5, which codes for the carboxy-terminal part of protein S and contains the complete 3' untranslated

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Zeng, Erliang, Giri Narasimhan, Lisa Schneper, and Kalai Mathee. "A Functional Network of Yeast Genes Using Gene Ontology Information." In 2008 IEEE International Conference on Bioinformatics and Biomedicine. IEEE, 2008. http://dx.doi.org/10.1109/bibm.2008.60.

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Teixeira, Lívia, Izabela Conceição, Paulo Caramelli, Marcelo Luizon, and Karina Gomes. "ALZHEIMER’S DISEASE AND TYPE 2 DIABETES MELLITUS: COMMON MIRNAS, GENES AND REGULATORY BIOLOGICAL PATHWAYS." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda066.

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Background: The increased incidence of Type 2 Diabetes Mellitus (T2DM) in the 21st century, along with the higher risk of developing Alzheimer’s disease (AD) in diabetic patients have stimulated the search for pathways that link glycemic disorders to neurodegeneration. MicroRNAs (miRNAs) are non-coding RNAs that play key roles in regulating gene expression. Objective: To identify miRNAs, genes and their regulatory pathways in common in AD and T2DM. Methods: Literature search was carried out to find miRNAs commonly expressed in AD and T2DM. MiRTarBase database was used to provide experimentally

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Yarshevich, A. V., and P. M. Marozik. "ANALYSIS OF ASSOCIATION OF VDR GENE VARIANTS WITH SERUM VITAMIN D LEVEL IN PATIENTS WITH BONE-MUSCULAR DISEASE." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2021. http://dx.doi.org/10.46646/sakh-2021-2-146-149.

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Currently, the pathology of the musculoskeletal system is considered in several multifactorial diseases, the pathogenesis of which is complex and is due to the interaction of environmental and endogenous factors. An important role in the progression of pathology is played by disorders in metabolism and a decrease in sensitivity to vitamin D. Studies of the past two decades have shown that the various biological actions of the active metabolite of vitamin D - 1,25-dihydroxy vitamin D (calcitriol) - are carried out by modulating the expression of genes that are mediated by interaction with the i

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Berichte der Organisationen zum Thema "Functionnal genes"

Meir, Shimon, Michael Reid, Cai-Zhong Jiang, Amnon Lers, and Sonia Philosoph-Hadas. Molecular Studies of Postharvest Leaf and Flower Abscission. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7696523.bard.

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Original objectives: Understanding the regulation of abscission competence by exploring the nature and function of auxin-related gene expression changes in the leaf and pedicelAZs of tomato (as a model system), was the main goal of the previously submitted proposal. We proposed to achieve this goal by using microarray GeneChip analysis, to identify potential target genes for functional analysis by virus-induced gene silencing (VIGS). To increase the potential of accomplishing the objectives of the previously submitted proposal, we were asked by BARD to show feasibility for the use of these two

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Mawassi, Munir, Baozhong Meng, and Lorne Stobbs. Development of Virus Induced Gene Silencing Tools for Functional Genomics in Grapevine. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7613887.bard.

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Grapevine is perhaps the most widely grown fruit crop. To understand the genetic make-up so as to improve the yield and quality of grapes and grape products, researchers in Europe have recently sequenced the genomes of Pinot noir and its inbred. As expected, function of many grape genes is unknown. Functional genomics studies have become the major focus of grape researchers and breeders. Current genetic approaches for gene function studies include mutagenesis, crossing and genetic transformation. However, these approaches are difficult to apply to grapes and takes long periods of time to accom

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Levin, Ilan, John W. Scott, Moshe Lapidot, and Moshe Reuveni. Fine mapping, functional analysis and pyramiding of genes controlling begomovirus resistance in tomato. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7594406.bard.

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Abstract. Tomato yellow leaf curl virus (TYLCV), a monopartitebegomovirus, is one of the most devastating viruses of cultivated tomatoes and poses increasing threat to tomato production worldwide. Because all accessions of the cultivated tomato are susceptible to these viruses, wild tomato species have become a valuable resource of resistance genes. QTL controlling resistance to TYLCV and other begomoviruses (Ty loci) were introgressed from several wild tomato species and mapped to the tomato genome. Additionally, a non-isogenic F₁diallel study demonstrated that several of these resistance sou

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Lifschitz, Eliezer, and Elliot Meyerowitz. The Relations between Cell Division and Cell Type Specification in Floral and Vegetative Meristems of Tomato and Arabidopsis. United States Department of Agriculture, 1996. http://dx.doi.org/10.32747/1996.7613032.bard.

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Meristems were the central issue of our project. Genes that are required for cell division, cell elongation, cell proliferation and cell fate were studied in the tomato system. The analysis of the dUTPase and threonine deaminase genes, along with the dissection of their regulatory regions is completed, while that of the RNR2 and PPO genes is at an advanced stage. All these genes were isolated in our laboratory. In addition, 8 different MADS box genes were studied in transgenic plants and their genetic relevances discovered. We have also shown that a given MADS box gene can modify the polarity

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Lichter, Amnon, Gopi K. Podila, and Maria R. Davis. Identification of Genetic Determinants that Facilitate Development of B. cinerea at Low Temperature and its Postharvest Pathogenicity. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7592641.bard.

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Botrytis cinerea is the postharvest pathogen of many agricultural produce with table grapes, strawberries and tomatoes as major targets. The high efficiency with which B. cinerea causes disease on these produce during storage is attributed in part due to its exceptional ability to develop at very low temperature. Our major goal was to understand the genetic determinants which enable it to develop at low temperature. The specific research objectives were: 1. Identify expression pattern of genes in a coldenriched cDNA library. 2. Identify B. cinerea orthologs of cold-induced genes 3. Profile pro

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Busov, Victor. Functional Gene Discovery and Characterization of Genes and Alleles Affecting Wood Biomass Yield and Quality in Populus. Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1343386.

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Katzir, Nurit, James Giovannoni, Marla Binzel, Efraim Lewinsohn, Joseph Burger, and Arthur Schaffer. Genomic Approach to the Improvement of Fruit Quality in Melon (Cucumis melo) and Related Cucurbit Crops II: Functional Genomics. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592123.bard.

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Background: Genomics tools for enhancement of melon research, with an emphasis on fruit, were developed through a previous BARD project of the PIs (IS -333-02). These included the first public melon EST collection, a database to relay this information to the research community and a publicly available microarray. The current project (IS-3877- 06) aimed to apply these tools for identification of important genes for improvement of melon (Cucumis melo) fruit quality. Specifically, the research plans included expression analysis using the microarray and functional analyses of selected genes. The o

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Dubcovsky, Jorge, Tzion Fahima, Ann Blechl, and Phillip San Miguel. Validation of a candidate gene for increased grain protein content in wheat. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7695857.bard.

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High Grain Protein Content (GPC) of wheat is important for improved nutritional value and industrial quality. However, selection for this trait is limited by our poor understanding of the genes involved in the accumulation of protein in the grain. A gene with a large effect on GPC was detected on the short arm of chromosome 6B in a Triticum turgidum ssp. dicoccoides accession from Israel (DIC, hereafter). During the previous BARD project we constructed a half-million clones Bacterial Artificial Chromosome (BAC) library of tetraploid wheat including the high GPC allele from DIC and mapped the G

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King, Mary-Claire, and Piri L. Welcsh. Novel Functional Screen for New Breast Cancer Genes. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada433029.

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Lers, Amnon, and Gan Susheng. Study of the regulatory mechanism involved in dark-induced Postharvest leaf senescence. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7591734.bard.

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Postharvest leaf senescence contributes to quality losses in flowers and leafy vegetables. The general goal of this research project was to investigate the regulatory mechanisms involved in dark-induced leaf senescence. The regulatory system involved in senescence induction and control is highly complex and possibly involves a network of senescence promoting pathways responsible for activation of the senescence-associated genes. Pathways involving different internal signals and environmental factors may have distinctive importance in different leaf senescence systems. Darkness is known to have

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