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1

Toner, Mehmet. "Thermodynamics and kinetics of ice nucleation inside biological cells during freezing : as applied to mouse oocytes." Thesis, Massachusetts Institute of Technology, 1989. http://hdl.handle.net/1721.1/29199.

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Thesis (Ph. D.)--Harvard University--Massachusetts Institute of Technology Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1989.<br>Includes bibliographical references (leaves 372-393).<br>by Mehmet Toner.<br>Ph.D.
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2

Huang, Hayden. "Cellular responses to mechanical stresses applied via magnetic manipulators." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/8349.

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Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, February 2002.<br>Includes bibliographical references (p. 99-103).<br>A mechanotransduction model aims to explain how a cell senses mechanical forces and translates them into molecular events, such as changes in intracellular ion concentrations, gene expression, post-translational protein modification, or cytoskeletal redistribution. Many studies of mechanotransduction explore the responses of cell populations to large and, occasionally, poorly characterized deformation. More recent techn
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3

Au, Pakwai. "Engineering functional blood vessels in vivo." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43867.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.<br>Includes bibliographical references.<br>At the present time, there are many hurdles to overcome in order to create a long-lasting and engineered tissue for tissue transplant in patients. The challenges include the isolation and expansion of appropriate cells, the arrangement of assorted cells into correct spatial organization, and the development of proper growth conditions. Furthermore, the creation of a three dimensional engineered tissue is limited by the fact that tissue assemblies greater than 100-200 microm
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4

Elisseeff, Jennifer Hartt 1973. "Transdermal photopolymerization of hydrogels for tissue engineering." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/84773.

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5

Von, Maltzahn Geoffrey. "A systems approach to engineering cancer nanotechnologies." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/58387.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, February 2010.<br>Vita. Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 203-210).<br>therapy. Over the past three decades, advances in nanomaterial synthesis have produced impressive nanostructures with unique electromagnetic and therapeutic properties. These represent a powerful toolkit of building blocks through which multi-component nanosystems could be constructed. Yet, while biological systems produce higher-order functions through coordinated interactions between multiple nanoscale c
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6

Zhu, Ting F. (Ting Fredrick). "Engineering artificial cell membranes by Ting F. Zhu." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/58299.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2010.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Growth and division are essential biological processes of cellular life. A crucial question concerning the origin of cellular life is how primitive cells (protocells) lacking complex biological machinery could grow and divide. To address this question, we first developed an effective method for preparing large monodisperse (uniform-sized) vesicles through a combination of extrusion and large-pore dialysis. The development of this pre
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7

Tam, Joshua. "Adipogenesis and angiogenesis : roles in tissue engineering and glucose metabolism." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54590.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 118-127).<br>Adipose tissue serves two main functions in the body: (1) it is the body's primary energy depot; and (2) it also serves as an important endocrine organ, producing and secreting various enzymes, growth factors, cytokines, and hormones. Both of these functions require ample access to circulating blood. Many aspects of angiogenesis during adipose tissue expansion remain poorly understood. Adipocytes produce a large variety
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8

Kearney, Cathal (Cathal John). "Non-invasive shock wave stimulated periosteum for bone tissue engineering." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/63082.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 211-225).<br>The cambium cells of the periosteum, which are known osteoprogenitor cells, have limited suitability for clinical applications of bone tissue engineering due to their low cell number (2-5 cells thick). Extracorporeal shock waves (ESWs) have been reported to cause thickening of the cambium layer and subsequent periosteal osteogenesis. This work proposes that ESW-therapy can be used as a non-invasive, inexpensive, and rapi
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9

Alterovitz, Gil 1975. "A Bayesian framework for statistical signal processing and knowledge discovery in proteomic engineering." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/34479.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, February 2006.<br>Includes bibliographical references (leaves 73-85).<br>Proteomics has been revolutionized in the last couple of years through integration of new mass spectrometry technologies such as -Enhanced Laser Desorption/Ionization (SELDI) mass spectrometry. As data is generated in an increasingly rapid and automated manner, novel and application-specific computational methods will be needed to deal with all of this information. This work seeks to develop a Bayesian framework in mass-based proteomics for protein i
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10

Chen, Patty P. 1981. "Lung tissue engineering : in vitro synthesis of lung tissue from neonatal and fetal rat lung cells cultured in a three-dimensional collagen matrix." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28758.

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Thesis (M. Eng.)--Harvard-MIT Division of Health Sciences and Technology, 2004.<br>Includes bibliographical references (p. 76-77).<br>The focus of this study was to investigate the histology of tissue formed when fetal (16-20 days gestation) and neonatal (2 days old) rat lung cells were grown in a collagen-glycosaminoglycan scaffold. This project employed a collagen-GAG scaffold specifically developed for tissue engineering and investigated the effect of this substratum on the formation of lung histotypic structures in vitro. A cell isolation procedure was developed whereby 19-days gestation t
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11

Yoo, Seung-Schik 1970. "Adaptive functional magnetic resonance imaging." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/70893.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 2000.<br>Some research performed with the Harvard-M.I.T. Division of Health Sciences and Technology.<br>Includes bibliographical references (leaves 132-140).<br>Functional MRI (fMRI) detects the signal associated with neuronal activation, and has been widely used to map brain functions. Locations of neuronal activation are localized and distributed throughout the brain, however, conventional encoding methods based on k-space acquisition have limited spatial selectivity. To improve it, we propose an adaptive fM
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12

Zhang, Li 1969. "Near field three-dimensional coded aperture techniques : theoretical and experimental exploration for applications in imaging and detection systems." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9849.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering; and, Harvard-MIT Division of Health Sciences and Technology, 1998.<br>Includes bibliographical references (leaves 149-154).<br>by Li Zhang.<br>Ph.D.
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13

Syed, Zeeshan Hassan 1980. "Computational methods for physiological data." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54671.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>Author is also affiliated with the MIT Dept. of Electrical Engineering and Computer Science. Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 177-188).<br>Large volumes of continuous waveform data are now collected in hospitals. These datasets provide an opportunity to advance medical care, by capturing rare or subtle phenomena associated with specific medical conditions, and by providing fresh insights into disease dynamics over long time scales. We describe how progress in medici
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14

Smith, Joseph Martin. "The stochastic nature of cardiac electrical instability : theory and experiment." Thesis, Massachusetts Institute of Technology, 1985. http://hdl.handle.net/1721.1/14339.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology, 1986.<br>Vita.<br>Includes bibliographical references (leaves 190-206).<br>by Joseph Martin Smith.<br>Ph.D.
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15

Stearns, Charles William. "Accelerated image reconstruction for a cylindrical positron tomograph using Fourier domain methods." Thesis, Massachusetts Institute of Technology, 1990. http://hdl.handle.net/1721.1/29201.

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Thesis (Ph. D.)--Harvard University--Massachusetts Institute of Technology Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1990.<br>Includes bibliographical references (leaves 142-150).<br>by Charles William Stearns.<br>Ph.D.
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16

Lotz, Jeffrey Charles. "Hip fracture risk predictions by x-ray computed tomography." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/14410.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1988.<br>Includes bibliographical references.<br>by Jeffrey Charles Lotz.<br>Ph.D.
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17

Albrecht, Paul 1956. "Stochastic characterization of chronic ventricular ectopic activity." Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/29514.

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Thesis (Ph.D.)--Harvard-Massachusetts Institute of Technology Division of Health Science and Technology Program in Medical Engineering and Medical Physics, 1986.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.<br>Bibliography: leaves 277-289.<br>by Paul Albrecht.<br>Ph.D.
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18

Ladin, Zvi. "Set-theoretic analysis of multi-link systems with applications to gait." Thesis, Massachusetts Institute of Technology, 1985. http://hdl.handle.net/1721.1/17201.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1985.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.<br>Bibliography: leaves 163-169.<br>by Zvi Ladin.<br>Ph.D.
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19

Burstein, Deborah. "NMR studies of intracellular sodium in the perfused frog heart." Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/17203.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1986.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.<br>Bibliography: leaves 140-153.<br>by Deborah Burstein.<br>Ph.D.
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20

Walsh, Joseph Tonry. "Pulsed laser ablation of tissue : analysis of the removal process and tissue healing." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/14412.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1988.<br>Includes bibliographical references.<br>by Joseph T. Walsh, Jr.<br>Ph.D.
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21

Wodicka, George R. "Acoustic transmission in the respiratory system." Thesis, Massachusetts Institute of Technology, 1989. http://hdl.handle.net/1721.1/29200.

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Thesis (Ph. D.)--Harvard University--Massachusetts Institute of Technology MIT Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1989.<br>Vita.<br>Includes bibliographical references (leaves 161-163).<br>by George Robert Wodicka.<br>Ph.D.
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22

Chernoff, Daniel Michael. "Kinetics of local anesthetic binding to sodium channels : role of pKa̳." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/29203.

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Thesis (Ph. D.)--Harvard University--Massachusetts Institute of Technology Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1989.<br>On t.p. "a" is subscript.<br>Includes bibliographical references (leaves 165-175).<br>by Daniel Michael Chernoff.<br>Ph.D.
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23

Prince, Martin Raymond. "Selective laser ablation of diseased tissue : investigations on a safe method of opening occluded arteries." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/14411.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1988.<br>Includes bibliographical references.<br>by Martin R. Prince.<br>Ph.D.
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24

Saltzman, William Mark. "A microstructural approach for modelling diffusion of bioactive macromolecules in porous polymers." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/14625.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1987.<br>Bibliography: v. 2, leaves 335-343.<br>by William Mark Saltzman.<br>Ph.D.
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25

McFarland, Eric W. (Eric Wesley). "Nuclear spin transfer studies of chemical reactions in living systems." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/17215.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1987.<br>Bibliography: leaves 212-227.<br>by Eric W. McFarland.<br>Ph.D.
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26

Carley, David William. "The stability of respiratory control in man : mathematical and experimental analyses." Thesis, Massachusetts Institute of Technology, 1985. http://hdl.handle.net/1721.1/17192.

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Thesis (Ph. D.)--M.I.T., Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1985.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIECNE.<br>Vita.<br>Includes bibliographical references.<br>by David William Carley.<br>Ph.D.
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27

Cheal, Edward John. "Trabecular bone remodeling around implants." Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/17204.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1986.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.<br>Bibliography: p. 332-347.<br>by Edward John Cheal.<br>Ph.D.
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28

Chueh, Henry C. "Integration of expert knowledge into computer-controlled databases in the medical domain : HEMAVID, a case study." Thesis, Massachusetts Institute of Technology, 1989. http://hdl.handle.net/1721.1/29202.

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Thesis (M.S.)--Harvard University--Massachusetts Institute of Technology Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1989.<br>Includes bibliographical references (leaves [165]-[172]).<br>by Henry C. Chueh.<br>M.S.
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29

Gray, Martha Lane. "Physical regulation of epiphyseal cartilage biosynthesis : responses to electrical, mechanical, and chemical signals." Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/17205.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1986.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.<br>Bibliography: leaves 194-205.<br>by Martha Lane Gray.<br>Ph.D.
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30

Powell, Kevin. "Mammalian cell clonal growth and secretion measurements using gel microdroplets and flow cytometry." Thesis, Massachusetts Institute of Technology, 1989. http://hdl.handle.net/1721.1/29198.

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Thesis (Ph. D.)--Harvard University--Massachusetts Institute of Technology Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1989.<br>Includes bibliographical references (leaves 94-98).<br>by Kevin Thomas Powell.<br>Ph.D.
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31

Valor, Sabatier Josep. "Mathematical tools and budgetary mechanisms for hospital cost control." Thesis, Massachusetts Institute of Technology, 1985. http://hdl.handle.net/1721.1/29513.

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Thesis (Sc. D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1985.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE<br>Bibliography: leaves 140-146.<br>by Josep Valor Sabatier.<br>Sc.D.
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32

Sung, Cynthia. "A study of polyethylene oxide-polysiloxane networks as biomaterials for drug release." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/14501.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1989.<br>Includes bibliographical references.<br>by Cynthia Sung.<br>Ph.D.
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33

Allbritton, Nancy L. (Nancy Lynn). "The role of calcium in the destruction of target cells by cytotoxic T cells." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/29517.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Divison of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1987.<br>Title as it appears in M.I.T. Graduate List, June 1987: The role of calcium in the destruction of target cells by cytotoxic T lymphocytes.<br>Bibliography: leaves 224-239.<br>by Nancy L. Allbritton.<br>Ph.D.
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