Thematische Bibliographien / Hydrophobic

Inhaltsverzeichnis

  1. Zeitschriftenartikel
  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte
  6. Berichte der Organisationen

Auswahl der wissenschaftlichen Literatur zum Thema „Hydrophobic“

Autor: Grafiati
Veröffentlicht am 4. Juni 2021
Zuletzt aktualisiert am 25. Juli 2025

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Zeitschriftenartikel zum Thema "Hydrophobic"

1

Vaishnavi, Kulwal, I. Mohamed Zara, P. Bhangui Varad, Jumnani Prohit, and Shraddha Kulkarni Dr. "Utilization of Fungal Proteins in Increasing Bioavailability and Stability of Hydrophobic Drugs." International Journal of Innovative Science and Research Technology 8, no. 5 (2023): 602–11. https://doi.org/10.5281/zenodo.7950921.

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Hydrophobins are a group of small, low molecular weight cysteine-rich fungal proteins found in the hyphae walls of fungi. Due to their composition, hydrophobins have the surface-modifying ability to form an amphiphilic membrane at the hydrophobichydrophilic interface in an aqueous solution which can be used to coat hydrophobic surfaces and change their nature. This property has applications in increasing the bioavailability of low aqueous solubility hydrophobic compounds by preparation of nanosuspensions. The low solubility hinders their efficacy in being used as therapeutic drugs. The objecti
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Scholtmeijer, Karin, Meike I. Janssen, Bertus Gerssen, et al. "Surface Modifications Created by Using Engineered Hydrophobins." Applied and Environmental Microbiology 68, no. 3 (2002): 1367–73. http://dx.doi.org/10.1128/aem.68.3.1367-1373.2002.

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ABSTRACT Hydrophobins are small (ca. 100 amino acids) secreted fungal proteins that are characterized by the presence of eight conserved cysteine residues and by a typical hydropathy pattern. Class I hydrophobins self-assemble at hydrophilic-hydrophobic interfaces into highly insoluble amphipathic membranes, thereby changing the nature of surfaces. Hydrophobic surfaces become hydrophilic, while hydrophilic surfaces become hydrophobic. To see whether surface properties of assembled hydrophobins can be changed, 25 N-terminal residues of the mature SC3 hydrophobin were deleted (TrSC3). In additio
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Scholtmeijer, K., M. I. Janssen, M. B. M. van Leeuwen, T. G. van Kooten, H. Hektor, and H. A. B. Wösten. "The use of hydrophobins to functionalize surfaces." Bio-Medical Materials and Engineering 14, no. 4 (2004): 447–54. https://doi.org/10.1177/095929892004014004011.

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The physiochemical nature of surfaces can be changed by small proteins which are secreted by filamentous fungi. These proteins, called hydrophobins, are characterized by the presence of eight conserved cysteine residues and a typical hydropathy pattern. Upon contact with a hydrophilic–hydrophobic interface they self‐assemble into highly insoluble amphipathic membranes. As a result, hydrophobic surfaces become hydrophilic and vice versa. Genetic engineering of hydrophobins was used to study structure–function relationships. In addition, engineered hydrophobins were constructed to increase the b
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Pennacchio, Anna, Paola Cicatiello, Eugenio Notomista, Paola Giardina, and Alessandra Piscitelli. "New clues into the self-assembly of Vmh2, a basidiomycota class I hydrophobin." Biological Chemistry 399, no. 8 (2018): 895–901. http://dx.doi.org/10.1515/hsz-2018-0124.

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Abstract Hydrophobins are fungal proteins that can self-assemble into amphiphilic films at hydrophobic-hydrophilic interfaces. Class I hydrophobin aggregates resemble amyloid fibrils, sharing some features with them. Here, five site-directed mutants of Vmh2, a member of basidiomycota class I hydrophobins, were designed and characterized to elucidate the molecular determinants playing a key role in class I hydrophobin self-assembly. The mechanism of fibril formation proposed for Vmh2 foresees that the triggering event is the destabilization of a specific loop (L1), leading to the formation of a
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Teertstra, Wieke R., Heine J. Deelstra, Miroslav Vranes, et al. "Repellents have functionally replaced hydrophobins in mediating attachment to a hydrophobic surface and in formation of hydrophobic aerial hyphae in Ustilago maydis." Microbiology 152, no. 12 (2006): 3607–12. http://dx.doi.org/10.1099/mic.0.29034-0.

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Ustilago maydis contains one repellent and two class I hydrophobin genes in its genome. The repellent gene rep1 has been described previously. It encodes 11 secreted repellent peptides that result from the cleavage of a precursor protein at KEX2 recognition sites. The hydrophobin gene hum2 encodes a typical class I hydrophobin of 117 aa, while hum3 encodes a hydrophobin that is preceded by 17 repeat sequences. These repeats are separated, like the repellent peptides, by KEX2 recognition sites. Gene hum2, but not hum3, was shown to be expressed in a cross of two compatible wild-type strains, su
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Ahn, Sang-Oh, Ho-Dong Lim, Sung-Hwan You, Dae-Eun Cheong, and Geun-Joong Kim. "Soluble Expression and Efficient Purification of Recombinant Class I Hydrophobin DewA." International Journal of Molecular Sciences 22, no. 15 (2021): 7843. http://dx.doi.org/10.3390/ijms22157843.

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Hydrophobins are small proteins (<20 kDa) with an amphipathic tertiary structure that are secreted by various filamentous fungi. Their amphipathic properties provide surfactant-like activity, leading to the formation of robust amphipathic layers at hydrophilic–hydrophobic interfaces, which make them useful for a wide variety of industrial fields spanning protein immobilization to surface functionalization. However, the industrial use of recombinant hydrophobins has been hampered due to low yield from inclusion bodies owing to the complicated process, including an auxiliary refolding step. H
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Carro, Shirley, Valeria J. Gonzalez-Coronel, Jorge Castillo-Tejas, Hortensia Maldonado-Textle, and Nancy Tepale. "Rheological Properties in Aqueous Solution for Hydrophobically Modified Polyacrylamides Prepared in Inverse Emulsion Polymerization." International Journal of Polymer Science 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/8236870.

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Inverse emulsion polymerization technique was employed to synthesize hydrophobically modified polyacrylamide polymers with hydrophobe contents near to feed composition. Three different structures were obtained: multisticker, telechelic, and combined. N-Dimethyl-acrylamide (DMAM), n-dodecylacrylamide (DAM), and n-hexadecylacrylamide (HDAM) were used as hydrophobic comonomers. The effect of the hydrophobe length of comonomer, the initial monomer, and surfactant concentrations on shear viscosity was studied. Results show that the molecular weight of copolymer increases with initial monomer concen
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Serva, Alessandra, Mathieu Salanne, Martina Havenith, and Simone Pezzotti. "Size dependence of hydrophobic hydration at electrified gold/water interfaces." Proceedings of the National Academy of Sciences 118, no. 15 (2021): e2023867118. http://dx.doi.org/10.1073/pnas.2023867118.

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Hydrophobic hydration at metal/water interfaces actively contributes to the energetics of electrochemical reactions, e.g. CO2 and N2 reduction, where small hydrophobic molecules are involved. In this work, constant applied potential molecular dynamics is employed to study hydrophobic hydration at a gold/water interface. We propose an adaptation of the Lum–Chandler–Weeks (LCW) theory to describe the free energy of hydrophobic hydration at the interface as a function of solute size and applied voltage. Based on this model we are able to predict the free energy cost of cavity formation at the int
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Ohtaki, Shinsaku, Hiroshi Maeda, Toru Takahashi, et al. "Novel Hydrophobic Surface Binding Protein, HsbA, Produced by Aspergillus oryzae." Applied and Environmental Microbiology 72, no. 4 (2006): 2407–13. http://dx.doi.org/10.1128/aem.72.4.2407-2413.2006.

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ABSTRACT Hydrophobic surface binding protein A (HsbA) is a secreted protein (14.5 kDa) isolated from the culture broth of Aspergillus oryzae RIB40 grown in a medium containing polybutylene succinate-co-adipate (PBSA) as a sole carbon source. We purified HsbA from the culture broth and determined its N-terminal amino acid sequence. We found a DNA sequence encoding a protein whose N terminus matched that of purified HsbA in the A. ozyzae genomic sequence. We cloned the hsbA genomic DNA and cDNA from A. oryzae and constructed a recombinant A. oryzae strain highly expressing hsbA. Orthologues of H
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Kazmierczak, Pam, Dae Hyuk Kim, Massimo Turina, and Neal K. Van Alfen. "A Hydrophobin of the Chestnut Blight Fungus, Cryphonectria parasitica, Is Required for Stromal Pustule Eruption." Eukaryotic Cell 4, no. 5 (2005): 931–36. http://dx.doi.org/10.1128/ec.4.5.931-936.2005.

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ABSTRACT Hydrophobins are abundant small hydrophobic proteins that are present on the surfaces of many filamentous fungi. The chestnut blight pathogen Cryphonectria parasitica was shown to produce a class II hydrophobin, cryparin. Cryparin is the most abundant protein produced by this fungus when grown in liquid culture. When the fungus is growing on chestnut trees, cryparin is found only in the fungal fruiting body walls. Deletion of the gene encoding cryparin resulted in a culture phenotype typical of hydrophobin deletion mutants of other fungi, i.e., easily wettable (nonhydrophobic) hyphae.
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Dissertationen zum Thema "Hydrophobic"

1

Mancera, Ricardo Luis. "Understanding the hydrophobic effect." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627110.

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Pazhianur, Rajesh R. "Hydrophobic Forces in Flotation." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/28066.

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An atomic force microscope (AFM) has been used to conduct force measurements to better understand the role of hydrophobic forces in flotation. The force measurements were conducted between a flat mineral substrate and a hydrophobic glass sphere in aqueous solutions. It is assumed that the hydrophobic glass sphere may simulate the behavior of air bubbles during flotation. The results may provide information relevant to the bubble-particle interactions occurring during flotation. The glass sphere was hydrophobized by octadecyltrichlorosilane so that its water contact angle was 109 degrees. The m
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Cochin, D., P. Hendlinger, and André Laschewsky. "Polysoaps with fluorocarbon hydrophobic chains." Universität Potsdam, 1995. http://opus.kobv.de/ubp/volltexte/2008/1734/.

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A series of amphiphilic copolymers is prepared by copolymerization of choline methacrylate with 1,1,2,2-tetrahydroperfluorooctyl methacrylate in varying amounts. The copolymers bearing fluorocarbon chains are studied concerning their effects on viscosity, solubilization and surface activity in aqueous solution, exhibiting a general behavior characteristic for polysoaps. The results are compared with the ones obtained for an analogous series of amphiphilic copolymers bearing hydrocarbon chains.
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Quyum, Abdul. "Water migration through hydrophobic soils." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ65008.pdf.

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Singh, Baljit. "Studies on hydrophobic dendrimer nanoparticles." Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428133.

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Matthews, Andrew Ernest. "Synthesis of hydrophobic crosslinkable resins." Thesis, Kingston University, 1989. http://eprints.kingston.ac.uk/20528/.

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After reviewing the literature relating to the synthesis and properties of hydrophobic materials, and then considering potential methods for their synthesis, a route for the preparation of novel materials was chosen. A reaction scheme involving the condensation of an excess of 1,4-bis (chloromethyl) benzene with bisphenolic compounds, and conversion of the resultant chloromethyl products to their vinyl analogues is described. A variety of methods were used to accomplish the initial etherification. The use of dimethyl acetamide and potassium carbonate was found to reduce the incidence of side r
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Pan, Lei. "Hydrophobic Forces in Wetting Films." Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/76918.

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Flotation is an important separation process used in the mining industry. The process is based on hydrophobizing a selected mineral using an appropriate surfactant, so that an air bubble can spontaneously adhere on the mineral surface. The bubble-particle adhesion is possible only when the thin film of water between the bubble and particle ruptures, just like when two colloidal particles or air bubbles adhere with each other. Under most flotation conditions, however, both the double-layer and dispersion forces are repulsive, which makes it difficult to model the rupture of the wetting films us
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Boyett, Robin Ernest. "Computational studies of hydrophobic porphyrins." Thesis, University of Sussex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241621.

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Yang, Fan 1980. "Solvent mediated interaction between hydrophobic spheres." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84087.

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We develop a coarse grained methodology to study solvent mediated interactions between two or more hydrophobic spheres. The free energy of a configuration of two hydrophobic hard spheres is calculated as a function of their separation to understand the thermodynamic force between them mediated by water. The range of the hydrophobic interaction is found to be of the order of the equilibrium correlation length of water; beyond this range the hydrophobicity induced force is negligible. We also examine the free energy landscape corresponding to the two interacting hydrophobic spheres, and f
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Lipnizki, Frank. "Hydrophobic pervaporation : process integration and optimisation." Thesis, University of Bath, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343775.

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Bücher zum Thema "Hydrophobic"

1

Eunice, Li-Chan, ed. Hydrophobic interactions in food systems. CRC Press, 1988.

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Tuulmets, Ants. Ultrasound and hydrophobic interactions in solutions. Nova Science Publishers, 2010.

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Li, Zhaohao, Jinjin Yang, Hongming Fu, and Haiping Chen. Hydrophobic Ceramic Membranes for CO2 Capture. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-77678-6.

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1936-, Laskowski J., Poling G. W, and Conference of Metallurgists (34th : 1995 : Vancouver, B.C.), eds. Processing of hydrophobic minerals and fine coal. Canadian Institute of Mining, Metallurgy and Petroleum, 1995.

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Hansch, Corwin H. Exploring QSAR: Hydrophobic, electronic, and steric constants. American Chemical Society, 1995.

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Tronin, V. N. Energetics and percolation properties of hydrophobic nanoporous media. Nova Science Publishers, 2010.

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Pomroy, Neil Christopher. Solubilization of hydrophobic peptides by reversible cysteine PEGylation. National Library of Canada, 1999.

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Filho, Murillo Villela. Enantioselective reduction of hydrophobic keto compounds in multiphase bioreactor. Forschungszentrum, Zentralbibliothek, 2007.

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Rekker, Roelof F. Calculation of drug lipophilicity: Tte hydrophobic fragmental constant approach. VCH, 1992.

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M, Gschwend P., and Environmental Research Laboratory (Athens, Ga.), eds. Modeling the benthos-water column exchange of hydrophobic chemicals. U.S. Environmental Protection Agency, Environmental Research Laboratory, 1987.

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Buchteile zum Thema "Hydrophobic"

1

Kook, Daniel, Mehdi Shajari, and Thomas Kohnen. "Hydrophobic." In Encyclopedia of Ophthalmology. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-35951-4_487-3.

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Kook, Daniel, Mehdi Shajari, and Thomas Kohnen. "Hydrophobic." In Encyclopedia of Ophthalmology. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-540-69000-9_487.

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Gooch, Jan W. "Hydrophobic." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_6137.

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Gooch, Jan W. "Hydrophobic." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_6138.

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Gooch, Jan W. "Hydrophobic." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_13963.

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Thakur, Kirti, Swaroop Gharde, Sarang Jamdade, and Balasubramanian Kandasubramanian. "Hydrophobic and Super-Hydrophobic Polymer Coatings." In Smart Polymers. CRC Press, 2022. http://dx.doi.org/10.1201/9781003037880-11.

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Pratt, Lawrence. "Hydrophobic Effect." In Encyclopedia of Astrobiology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27833-4_704-3.

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Pratt, Lawrence. "Hydrophobic Effect." In Encyclopedia of Astrobiology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-44185-5_704.

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Liu, Fu. "Hydrophobic Membranes." In Encyclopedia of Membranes. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-44324-8_1678.

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Olea, Andrés F. "Hydrophobic Polyelectrolytes." In Ionic Interactions in Natural and Synthetic Macromolecules. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118165850.ch7.

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Konferenzberichte zum Thema "Hydrophobic"

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Koene, Bryan E., Adam Goff, Tammy Metroke, and Alaina McGregor. "Durable Hydrophobic Coatings for Metal Corrosion Protection." In CORROSION 2015. NACE International, 2015. https://doi.org/10.5006/c2015-05673.

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Abstract An exceptionally durable, transparent fluid resistant coating has been developed for corrosion mitigation on selected metals and alloys. This new coating is being presented as new surface treatment for improved protection of metallic substrates. There have been many recent research and commercial efforts in the area of hydrophobic or water repellent coatings that have demonstrated the ability to shed fluids quickly off of surfaces. Whereas many technologies and coatings have achieved the primary goal of achieving fluid shedding properties, they have all lacked mechanical / environment
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Peters, John. "Hydrophobic Coatings: Water Is No Match for Me." In Coatings+ 2019. SSPC, 2019. https://doi.org/10.5006/s2019-00041.

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Framatome identified a need to reduce radioactive contaminants on plant equipment and vendor supplied tooling, through the use of hydrophobic coatings, as a potential cost savings within the Nuclear Industry.
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Hirano, Susumu, Ayano Yasui, Hirotaka Mizukami, Tatsuya Sei, and Toshiyuki Sunaba. "Effect of Hydrophobic Interaction on Corrosion Inhibitor Efficiency." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17597.

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Abstract Surfactants are well known as an active ingredient of corrosion inhibitors; however, the molecular structure and its content of commercial inhibitors are not disclosed to users. The performance of commercial inhibitors was studied by treating the whole aspect of inhibitor as a kind of surfactant. The corrosion rate was measured with an autoclave by using an electrochemical measurement; namely, linear polarization resistance (LPR) in an oil flowline condition solution. Firstly, the corrosion rate was measured only with a corrosion inhibitor, and a hydrocarbon solvent was added afterwar
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Kostikov, V. I. "Modified hydrophobic concrete with reinforced hydrophobic properties." In ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ. НИЦ «Л-Журнал», 2018. http://dx.doi.org/10.18411/lj-05-2018-89.

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McNeely, Michael R., Mark K. Spute, Nadeem A. Tusneem, and Arnold R. Oliphant. "Hydrophobic microfluidics." In Symposium on Micromachining and Microfabrication, edited by Chong H. Ahn and A. Bruno Frazier. SPIE, 1999. http://dx.doi.org/10.1117/12.359339.

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Mejias-Brizuela, N. Y., A. Olivares-Pérez, G. Páez-Trujillo, M. P. Hernández-Garay, R. Fontanilla-Urdaneta, and I. Fuentes-Tapia. "Hydrophobic sugar holograms." In Integrated Optoelectronic Devices 2008, edited by Hans I. Bjelkhagen and Raymond K. Kostuk. SPIE, 2008. http://dx.doi.org/10.1117/12.761994.

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Thakkar, Shraddha, Rosa I. Sanchez, Chidambaram Bhuveneswaran, Cesar M. Compadre, and Olga Tarasenko. "EXPLORING HYDROPHOBIC BINDING SURFACES USING COMFA AND FLEXIBLE HYDROPHOBIC LIGANDS." In BIOLOGY, NANOTECHNOLOGY, TOXICOLOGY, AND APPLICATIONS: Proceedings of the 5th BioNanoTox and Applications International Research Conference. AIP, 2011. http://dx.doi.org/10.1063/1.3587465.

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Wu, Xiao, Ke Ji, Rixin Wang, Yusuke Tahara, Rui Yatabe, and Kiyoshi Toko. "Taste sensor using strongly hydrophobic membranes to measure hydrophobic substances." In 2016 10th International Conference on Sensing Technology (ICST). IEEE, 2016. http://dx.doi.org/10.1109/icsenst.2016.7796341.

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Yamaguchi, Haruki, Teruko Toyoda, and Tsutomu Arakawa. "COMPLEX-TYPE N-GLYCANS HAVE A HYDROPHOBIC PLANE AND STABILIZE PROTEIN CONFORMATION THROUGH HYDROPHOBIC INTERACTIONS WITH HYDROPHOBIC PROTEIN SURFACE." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.571.

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Klicova, Marketa, Lukas Volesky, Andrea Klapstova, Vaclav Liska Jachym Rosendorf, Richard Palek, and Jana Horakova. "Hydrophobic Ultrafine Hyaluronic Acid Nanofibers." In The 5th World Congress on New Technologies. Avestia Publishing, 2019. http://dx.doi.org/10.11159/icnfa19.151.

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Berichte der Organisationen zum Thema "Hydrophobic"

1

BUNKER, BRUCE C., DALE L. HUBER, MICHAEL S. KENT, et al. Switchable Hydrophobic-Hydrophilic Surfaces. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/806703.

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Drzymala, J., and T. D. Wheelock. Air agglomeration of hydrophobic particles. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/204691.

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Ioannides, Constantin G. Tumor Immunity by Hydrophobic Bearing Antigens. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada436894.

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Ioannides, Constantin G. Tumor Immunity by Hydrophobic Appendage Bearing Antigens. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada410277.

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Yoon, R., and G. Luttrell. Development of the Selective Hydrophobic Coagulation process. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/7055229.

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Yoon, R. H., and G. H. Luttrell. Development of the selective hydrophobic coagulation process. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/6879257.

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7

Cardin, Karl. Jet Rebound from Hydrophobic Substrates in Microgravity. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.6706.

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8

Chefetz, Benny, and Baoshan Xing. Sorption of hydrophobic pesticides to aliphatic components of soil organic matter. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7587241.bard.

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Annotation:
Sorption of hydrophobic compounds to aliphatic components of soil organic matter (SOM) is poorly understood even though these aliphatic carbons are a major fraction of SOM. The main source of aliphatic compounds in SOM is above- and below-ground plant cuticular materials (cutin, cutan and suberin). As decomposition proceeds, these aliphatic moieties tend to accumulate in soils. Therefore, if we consider that cuticular material contributes significantly to SOM, we can hypothesize that the cuticular materials play an important role in the sorption processes of hydrophobic compounds (including pe
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Marín Boyero, Adrián, and Miguel Angel Rodriguez Valverde. Shear adhesion of a sessile drop under a centrifugal field. Fundación Avanza, 2023. http://dx.doi.org/10.60096/fundacionavanza/1542022.

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EVANS, LINDSEY, and JAMES E. MILLER. Sweeping Gas Membrane Desalination Using Commercial Hydrophobic Hollow Fiber Membranes. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/793312.

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