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Auswahl der wissenschaftlichen Literatur zum Thema „Hypodernic Injections“

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Zeitschriftenartikel zum Thema "Hypodernic Injections"

1

S, Geetha Pushpanjali, Leela Praveena V, and Swamy P V. "NEEDLE FREE INJECTION TECHNOLOGY: A REVIEW." International Journal of Research in Ayurveda and Pharmacy 11, no. 5 (2020): 205–11. http://dx.doi.org/10.7897/2277-4343.1105170.

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Needleless injection systems are novel ways to introduce various medicines into patients without piercing a conventional needle. Needleless injection technology was developed to reduce the number of needle-stick accidents and associated problems; easy to use, disposable and their use is expected to increase considerably. Self-administration is feasible with these devices. This technology is used to deliver not only drugs but also proteins, peptides, monoclonal antibodies, small molecules and vaccines. This review describes pre-requisites, comparison between hypodermic and needle free injections, manufacturing process, components, types and marketed products.
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2

Gonçalves, Aparecido Carlos, Sidnei Cavassana, Fábio R. Chavarette, Roberto Outa, Samuel J. Casarin, and Adalberto Vieira Corazza. "Variation of the Penetration Effort in an Artificial Tissue by Hypodermic Needles." Journal of Healthcare Engineering 2020 (September 22, 2020): 1–12. http://dx.doi.org/10.1155/2020/8822686.

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Fear of injection-related pain is a drawback to injectable therapy. Hypodermic injections are a cause for great anxiety and reduced adherence to the subcutaneous application of insulin for glycemic control in diabetics or in the treatment of multiple sclerosis, increasing the risk of complications and mortality. Injured or sick people have to undergo several daily injections, forcing them to rotate the veins and regions used to recover from the trauma caused by the perforation of the skin, tissue, muscles, veins, and arteries. People who suffer from type 1 diabetes mellitus (DM1) need to have their glycemic control 3 to 5 times a day and to take insulin up to 3 times a day. In both cases, the patient needs to perforate the skin. To quantify the pain perceived by the patients depends on the evaluation of each patient and therefore is subjective. This study aims to understand the application and self-application of hypodermic injections and decrease pain during its application and the phobia of the patient, following the reasoning that the lower the effort to penetrate the needle, the less trauma in the tissue and therefore the pain provoked. For that, it was analyzed how some of the characteristics of the needle can influence the sensation of pain in the injection. The needle penetration effort was measured in an artificial tissue (substitute skin model) for different cannula diameters, roughness, depth of penetration, lubrication, and angles of the perforating tip bevel. This study aimed to find alternatives to facilitate the application and self-application of hypodermic injections, increase safety and comfort, and reduce the pain intensity perceived by the patient. To do this, the bevel of needles used repeatedly was analyzed in the profile projector and SEM to verify the loss of the profile or the formation of burrs that could hamper the penetration or traumatize the tissue during the reuse of needles. It has also been mechanically analyzed, which can be done to prevent that the needles used in the subcutaneous application do not inadvertently reach the muscle. The greater penetration effort observed in the needles with greater angle of the bevel is responsible for the patient’s perception of pain.
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3

Li, Wen, Yi Ming Zhang, and Jing Chen. "Design, Fabrication and Characterization of in-Plane Titanium Microneedles for Transdermal Drug Delivery." Key Engineering Materials 483 (June 2011): 532–36. http://dx.doi.org/10.4028/www.scientific.net/kem.483.532.

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Transdermal drug delivery is an alternative way to transport drugs compared with oral route and hypodermic injection. The problem of oral route is the degradation of drugs in the gastrointestinal tract and their elimination through the liver. The hypodermic injection is problematic due to the pain and inconvenient for patients [1]. As a novel device of transdermal drug delivery, microneedles offer several advantages including the painless injection, the precise penetration depth under the skin and the long-term, continuous deliveries
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4

Ryan, R. P. "Hypodermic injections of brain extract in mental diseases." British Journal of Psychiatry 164, no. 2 (1994): 270. http://dx.doi.org/10.1192/s0007125000050984.

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5

Landau, Marina. "Using cannulas for dermal filler placement: why, when and how?" Journal of Aesthetic Nursing 8, no. 5 (2019): 230–33. http://dx.doi.org/10.12968/joan.2019.8.5.230.

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Traditionally, dermal fillers have been administered to the face using a hypodermic needle. However, injecting using cannulas has become increasingly popular over the past decade, due to the changing goals of treatment, aims to improve patient experience and attemting to prevent complications. Many dermal filler products are now sold packaged with both a needle and a cannula in order to give the practitioner the choice of injection tool. It is therefore essential that the aesthetic practitioner is well educated on the topic of how to select the best injection tool for a procedure. This article aims to asses why we have seen an increase in the use of cannulas in administering this procedure, with the hope of helping the aesthetic practitioner to make the best decision regarding injection tools.
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6

Singh, Jagdeep, Anoop Kalia, Ravinder Kumar Banga, and Anshul Dahuja. "Broken needle in gluteal region following an intramuscular injection: a case report." International Journal of Research in Orthopaedics 5, no. 4 (2019): 744. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20192229.

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<p class="abstract">Incidence of broken hypodermic needle in patients has been decreased because of superior manufacturing techniques. Breaking of hypodermic needle after intramuscular injection has been rarely reported. We report a case of broken needle in the gluteal region in a 36 years old woman following an intramuscular injection. Patient arrived in the emergency after 2 days of the episode. Patient was taken for surgery for removal of the needle. Initially attempts for removal of needle were made without use of image intensifier under local anaesthesia, but it failed as it was very difficult to locate the needle. Patient was taken up for surgery under spinal anaesthesia with the use of image intensifier. Broken needle was located and removed. The following case describes the management of broken hypodermic needle and suggests valuable guidelines for minimising the chances of undue complications arising due to needle migration.</p>
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7

Karimi, Kian, Chester F. Griffiths, Alex Reivitis, Austin Davis-Hunter, Elizabeth Zhang, and Dorna Pourang. "Microcannula Utilization for Injectable Facial Fillers: Standard of Care?" American Journal of Cosmetic Surgery 35, no. 4 (2018): 189–97. http://dx.doi.org/10.1177/0748806818781633.

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The microcannula technique has become an increasingly popular method for injecting cosmetic fillers. Previous studies have illustrated that the microcannula technique allows filler to be injected with less pain, swelling, and essentially no bruising. This study is a retrospective clinical series examining 247 patients who have undergone dermal filler injections using the microcannula technique from 2011 to 2016 with a single injector, Kian Karimi. The purpose of this study is to assess the frequency of adverse events associated with injections such as bruising and swelling. All 666 recorded patient visits from 2011 to 2016 were analyzed using electronic medical records based on the criteria that the patients had cosmetic filler using the microcannula technique by the surgeon investigator. Of the 666 filler treatments using the microcannula technique, 3 treatments (0.5%) produced adverse events on the day of service, and 32 treatments (4.8%) produced adverse events at 2-week follow-up. In total, 5.4% of treatments produced adverse events. At the 2-week follow-up, 5.7% of treatments using the 25-gauge microcannula produced adverse events ( P = .830); 3.9% of treatments using the 27-gauge microcannula produced adverse events ( P = .612]). Only 3 patients were treated with the 30-gauge microcannula, and 1 patient reported adverse events on the day of service. None of the treatments using the 30-gauge microcannula produced adverse events at the 2-week follow-up ( P = .160). The data support that the microcannula technique is a safe and effective alternative to hypodermic needles for the injection of dermal filler to minimize common adverse events.
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8

Mohammed Bashir, Rabiu, Afeez Abdulrahman, and Zakari Suleiman. "Effectiveness of Bupivacaine Trigger Points Injections in the Treatment of Myofascial Pain Syndrome." Annals of Clinical and Experimental Medicine 1, no. 1 (2020): 23–28. http://dx.doi.org/10.47838/acem.26011977.11162020.asmeda.4.0.

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Background: Myofascial pain syndrome is a regional or widespread muscular pain associated with tenderness localized to linear or nodular hardening, trigger points in one or group of muscles. It is a major cause of time loss from work and low quality of life. Injections of myofascial trigger points either with local anaesthetics, steroid, normal saline or without any agent have been proven to provide pain relief. This study aims to determine the effectiveness of trigger point injection with bupivacaine in treatment of myofascial pain syndrome and improvement in quality of life. Methods: After Institutional Ethical Committee approval, forty one patients aged 16 years and above with myofacial pain syndrome had 0.5mls of 0.25% plain bupivacaine trigger points injections with size 26G 11 /2 inch hypodermic needle. Pain was assessed using Numerical Rating Scale and Pain disability questionnaire was administered to all the patients before the procedures and 1 month post-intervention (follow-up visits) to assessed functional and psychological component of pain disability scale and their response to treatment. Results:
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9

CHOU, S. M., L. Y. ZHAI, and E. S. H. YEOH. "THE EFFECT OF HYPODERMIC NEEDLE PERFORATIONS ON THE TENSILE PROPERTIES OF CHICKEN TENDONS." Journal of Mechanics in Medicine and Biology 06, no. 04 (2006): 447–53. http://dx.doi.org/10.1142/s0219519406002011.

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Corticosteroid injection using hypodermic needles is one of the commonly accepted treatments for patients with hand conditions. However, in some cases the needle perforations may cause tendon ruptures. This paper aims to investigate the relationships between a tendon's ultimate tensile strength (UTS) and the number of hypodermic needle perforations as well as needle sizes. The UTS was determined for all specimens at the loading rate of 0.4 mm/s. Tendon specimens with perforations punctured by large-sized (19 G) hypodermic needles were found to have significantly lower UTS than those with perforations punctured by medium-sized (23 G) and small-sized (27 G) needles. For specimens punctured by medium- and small-sized needles, no significant difference in UTS was observed between tendons with three perforations and those with one perforation.
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10

Botwin, Kenneth P. "Electromyographically Guided Trigger Point Injections in the Cervicothoracic Musculature of Obese Patients: A New and Unreported Technique." November 2007 6;10, no. 6;11 (2007): 753–56. http://dx.doi.org/10.36076/ppj.2007/10/753.

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Background: Myofascial pain is defined as pain that originates from myofascial trigger points in skeletal muscle. It is prevalent in regional musculoskeletal pain syndromes, either alone or in combination with other pain generators. The myofascial pain syndrome is one of the largest groups of under-diagnosed and under-treated medical problems encountered in clinical practice. Trigger points are commonly seen in patients with myofascial pain that can be responsible for localized pain in the affected muscles as well as referred pain patterns. Correct needle placement in a myofascial trigger point is vital to prevent complications and improve efficacy of the trigger point injection to help reduce or relieve myofascial pain. In the obese patients, these injections may not reach the target tissue. In the cervicothoracic spine, a misguided or misplaced injection can result in a pneumothorax. Here, we review an electromyographically guided trigger point injection technique to avoid this potential pitfall. Methods: Using a disposable Teflon coated hypodermic injection needle attached to an electromyography (EMG) machine, a trigger point injection can be performed utilizing electromyographic guidance. This guidance by observing motor unit action potentials (MUAPs) on the EMG screen helps confirm the needle placement to be within the muscle tissue and not in an adipose tissue or any other non-musculature structure. Results: The technique is simple when performed by a pain management specialist who has electromyographic training. Conclusion: This technique helps confirm proper needle placement within the cervicothoracic musculature in an obese patient in whom the musculature is not readily palpated. This, thus, reduces the potential for a pneumothorax by an improperly placed injection. Key words: Trigger point injection, myofascial pain, electromyography
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