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Thematische Bibliographien / Immediate loading. eng / Zeitschriftenartikel

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Zeitschriftenartikel zum Thema „Immediate loading. eng“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

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1

Hudgel, D. W., M. Mulholland, and C. Hendricks. "Neuromuscular and mechanical responses to inspiratory resistive loading during sleep." Journal of Applied Physiology 63, no. 2 (1987): 603–8. http://dx.doi.org/10.1152/jappl.1987.63.2.603.

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The purposes of this study were 1) to characterize the immediate inspiratory muscle and ventilation responses to inspiratory resistive loading during sleep in humans and 2) to determine whether upper airway caliber was compromised in the presence of a resistive load. Ventilation variables, chest wall, and upper airway inspiratory muscle electromyograms (EMG), and upper airway resistance were measured for two breaths immediately preceding and immediately following six applications of an inspiratory resistive load of 15 cmH2O.l–1 X s during wakefulness and stage 2 sleep. During wakefulness, ches

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Del Fabbro, Massimo, Tiziano Testori, Vladan Kekovic, Funda Goker, Margherita Tumedei, and Hom-Lay Wang. "A Systematic Review of Survival Rates of Osseointegrated Implants in Fully and Partially Edentulous Patients Following Immediate Loading." Journal of Clinical Medicine 8, no. 12 (2019): 2142. http://dx.doi.org/10.3390/jcm8122142.

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Background: The aim of this systematic review was to evaluate the survival rates of immediately loaded implants after at least five years. Besides implant failure, the amount of marginal bone loss around implants and the complication type were assessed. Methods: The electronic search was undertaken on Medline, Scopus, and Cochrane Central Register of Controlled Trials using key terms such as: “immediate loading”, “immediate function”, “immediate restoration”, “immediate temporization”, “dental implants”, “fully edentulous patients”, “partially edentulous patients”. The search terms were combin

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Zin, W. A., P. K. Behrakis, S. C. Luijendijk, et al. "Immediate response to resistive loading in anesthetized humans." Journal of Applied Physiology 60, no. 2 (1986): 506–12. http://dx.doi.org/10.1152/jappl.1986.60.2.506.

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In eight spontaneously breathing anesthetized subjects (halothane: approximately 1 minimal alveolar concn; 70% N2O-30% O2), we determined 1) the inspiratory driving pressure by analysis of the pressure developed at the airway opening (Poao) during inspiratory efforts against airways occluded at end expiration; 2) the active inspiratory impedance; and 3) the immediate (first loaded breath) response to added inspiratory resistive loads (delta R). Based on these data we made model predictions of the immediate tidal volume response to delta R. Such predictions closely fitted the experimental resul

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Kobylarz, E. J., and J. A. Daubenspeck. "Immediate diaphragmatic electromyogram responses to imperceptible mechanical loads in conscious humans." Journal of Applied Physiology 73, no. 1 (1992): 248–59. http://dx.doi.org/10.1152/jappl.1992.73.1.248.

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We used an esophageal electrode to measure the amplitude and neural inspiratory and expiratory (N TE) timing responses of crural diaphragmatic electrical activity in response to flow-resistive (R) and elastic (E) loads at or below the threshold for conscious detection, applied pseudorandomly to the oral airway of eight normal subjects. We observed a rapid first-breath neural reflex that modified respiratory timing such that N TE lengthened significantly in response to R loads in six of eight subjects and shortened in response to E loading in six of seven subjects. The prolongation of N TE with

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Andersen, Lars L., Christoffer H. Andersen, Ole S. Mortensen, Otto M. Poulsen, Inger Birthe T. Bjørnlund, and Mette K. Zebis. "Muscle Activation and Perceived Loading During Rehabilitation Exercises: Comparison of Dumbbells and Elastic Resistance." Physical Therapy 90, no. 4 (2010): 538–49. http://dx.doi.org/10.2522/ptj.20090167.

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BackgroundHigh-intensity resistance training plays an essential role in the prevention and rehabilitation of musculoskeletal injuries and disorders. Although resistance exercises with heavy weights yield high levels of muscle activation, the efficacy of more user-friendly forms of exercise needs to be examined.ObjectiveThe aim of this study was to investigate muscle activation and perceived loading during upper-extremity resistance exercises with dumbbells compared with elastic tubing.DesignA single-group, repeated-measures study design was used.SettingExercise evaluation was conducted in a la

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Rankinen, Katri, Eila Turtola, Riitta Lemola, Martyn Futter, and José Enrique Cano Bernal. "Nutrient Load Mitigation with Wintertime Cover as Estimated by the INCA Model." Water 13, no. 4 (2021): 450. http://dx.doi.org/10.3390/w13040450.

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Increased nutrient loading causes deterioration of receiving surface waters in areas of intensive agriculture. While nitrate and particulate phosphorus load can be efficiently controlled by reducing tillage frequency and increasing vegetation cover, many field studies have shown simultaneously increased loading of bioavailable phosphorus. In the latest phase of the Rural Programme of EU agri-environmental measures, the highest potential to reduce the nutrient loading to receiving waters were the maximum limits for fertilization of arable crops and retaining plant cover on fields with, e.g., no

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Kosch, P. C., P. W. Davenport, J. A. Wozniak, and A. R. Stark. "Reflex control of expiratory duration in newborn infants." Journal of Applied Physiology 58, no. 2 (1985): 575–81. http://dx.doi.org/10.1152/jappl.1985.58.2.575.

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We investigated the effect on expiratory duration (TE) of application of graded resistive and elastic loads and total airway occlusions to single expirations in 9 full-term healthy infants studied on the 2nd or 3rd day of life. The infants breathed through a face mask and pneumotachograph, and flow, volume, airway pressure, and diaphragm electromyogram (EMG) were recorded. Loads were applied to the expiratory outlet of a two-way respiratory valve using a manifold system. Application of all loads resulted in expired volumes (VE) decreased from control (P less than 0.05), and changes were progre

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Cheung, Vincent C. K., Andrea d'Avella, and Emilio Bizzi. "Adjustments of Motor Pattern for Load Compensation Via Modulated Activations of Muscle Synergies During Natural Behaviors." Journal of Neurophysiology 101, no. 3 (2009): 1235–57. http://dx.doi.org/10.1152/jn.01387.2007.

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It has been suggested that the motor system may circumvent the difficulty of controlling many degrees of freedom in the musculoskeletal apparatus by generating motor outputs through a combination of discrete muscle synergies. How a discretely organized motor system compensates for diverse perturbations has remained elusive. Here, we investigate whether motor responses observed after an inertial-load perturbation can be generated by altering the recruitment of synergies normally used for constructing unperturbed movements. Electromyographic (EMG, 13 muscles) data were collected from the bullfro

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Santagata, Mario, Luigi Guariniello, and Gianpaolo Tartaro. "Modified Edentulous Ridge Expansion Technique and Immediate Implant Placement: A 3-Year Follow-Up." Journal of Oral Implantology 41, no. 2 (2015): 184–87. http://dx.doi.org/10.1563/aaid-joi-d-12-00308.

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Restoration of the edentulous alveolar ridge with implants often requires the ridge width to be augmented to allow its placement. The aim of this study was to evaluate the split-crest technique, with subepithelial connective tissue graft used as biological barrier, in patients with narrow ridges, focusing on the status of soft and hard tissues and on implant success rate, at 36 months after implant loading. Thirteen patients (6 males and 7 females), ages 32–68 years (mean 49.4 years) with an atrophic maxillary jaw underwent modified edentulous ridge expansion technique for implant placement. A

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Dahl, Göran, Stephan Steigele, Per Hillertz, et al. "Unified Software Solution for Efficient SPR Data Analysis in Drug Research." SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, no. 2 (2016): 203–9. http://dx.doi.org/10.1177/1087057116675316.

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Surface plasmon resonance (SPR) is a powerful method for obtaining detailed molecular interaction parameters. Modern instrumentation with its increased throughput has enabled routine screening by SPR in hit-to-lead and lead optimization programs, and SPR has become a mainstream drug discovery technology. However, the processing and reporting of SPR data in drug discovery are typically performed manually, which is both time-consuming and tedious. Here, we present the workflow concept, design and experiences with a software module relying on a single, browser-based software platform for the proc

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Khorshid, Heba, and Nora Sheta. "Assessment of two different Splinting materials on the immediate functional loading of Implants placed in mandibular unilateral free end saddle cases." Egyptian Dental Journal 64, no. 4 (2018): 3535–42. http://dx.doi.org/10.21608/edj.2018.79175.

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Campbell, Veronique, and Daphne J. Fairbairn. "Prolonged copulation and the internal dynamics of sperm transfer in the water strider Aquarius remigis." Canadian Journal of Zoology 79, no. 10 (2001): 1801–12. http://dx.doi.org/10.1139/z01-148.

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Copulations lasting much longer than required to effect insemination are common throughout the Insecta, but their adaptive significance remains obscure. We address the hypothesis that prolonged copulations benefit male Aquarius remigis (Hemiptera, Gerridae) by influencing sperm use and storage following insemination. We describe the gynatrial complex of females and document sperm location immediately following 32 naturally terminated and 25 artificially terminated copulations. We also examine sperm storage in 22 females isolated from males for 210 days. Our results demonstrate that inseminati

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Chincotta, Dino, and Geoffrey Underwood. "Simultaneous interpreters and the effect of concurrent articulation on immediate memory." Interpreting. International Journal of Research and Practice in Interpreting 3, no. 1 (1998): 1–20. http://dx.doi.org/10.1075/intp.3.1.01chi.

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According to working memory theory (e.g., Baddeley, 1990), bilingual digit span is mediated by a variation in speech rate between the languages. This view is supported by findings that demonstrate the elimination of the bilingual digit span effect under concurrent articulation. The present study addressed the question as to how experienced simultaneous interpreters, experts in processing information whilst articulating a translation in a target language, cope with the deleterious effects of articulatory. suppression. Bilingual digit span with and without articulatory suppression was compared b

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Powell, Saul R., Ellen M. Gurzenda, Mark A. Wingertzahn, and Raul A. Wapnir. "Promotion of copper excretion from the isolated rat heart attenuates postischemic cardiac oxidative injury." American Journal of Physiology-Heart and Circulatory Physiology 277, no. 3 (1999): H956—H962. http://dx.doi.org/10.1152/ajpheart.1999.277.3.h956.

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This study examined the role of Cu as a mediator of cardiac postischemic oxidative injury. Isolated rat hearts were subjected to 20 min of normothermic global ischemia, followed by 30 min of reperfusion; after 20 min of preischemic loading with Krebs-Henseleit buffer ± 20 or 30 μM zinc-bis-histidinate (Zn-His2), 0.5 mM deferoxamine (DEF) or 42 μM neocuproine (NEO). Postischemic developed systolic pressure and rate-pressure product were highest and postischemic end-diastolic pressure was lowest in hearts treated with 20 or 30 μM Zn-His2 and 0.5 mM DEF. Cu efflux was significantly increased by 2

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Taniyama, Kiichi, Hideki Oda, Kazuko Okawa, Katsuhito Himeno, Koki Shikanai, and Tohru Shibutani. "Psychosedation With Dexmedetomidine Hydrochloride During Minor Oral Surgery." Anesthesia Progress 56, no. 3 (2009): 75–80. http://dx.doi.org/10.2344/0003-3006-56.3.75.

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Abstract We performed intravenous sedation with dexmedetomidine hydrochloride during minor oral surgery and compared this agent with propofol. Patients were randomly divided into 2 groups: dexmedetomidine hydrochloride (D) and propofol (P) groups. In Group D, systolic blood pressure (SBP) increased immediately after the start of initial loading, although no significant differences were noted. Both SBP and diastolic blood pressure (DBP) gradually decreased during maintenance administration and were significantly lower than pretreatment values. The heart rate decreased immediately after the star

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Coxson, Darwyn, Susan Stevenson, and Jocelyn Campbell. "Short-term impacts of partial cutting on lichen retention and canopy microclimate in an Engelmann spruce subalpine fir forest in north-central British Columbia." Canadian Journal of Forest Research 33, no. 5 (2003): 830–41. http://dx.doi.org/10.1139/x03-006.

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The retention of canopy lichens (Alectoria, Bryoria, and foliose) in group selection (GS) and single-tree selection (STS) partial cuts (30% removal) was studied within a subalpine sprucefir forest (Picea englemannii Parry ex Engelm. Abies lasiocarpa (Hook.) Nutt.) in north-central British Columbia. Baseline canopy lichen loading (preharvest and immediate postharvest) was compared with lichen loading 2 years after harvesting, using both ground- and canopy-based sampling techniques. Additionally, canopy microclimate was compared between GS and adjacent stand areas with no harvest treatment (N

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Holyoak, Derek T., Tibra A. Wheeler, Marjolein C. H. van der Meulen, and Ankur Singh. "Injectable mechanical pillows for attenuation of load-induced post-traumatic osteoarthritis." Regenerative Biomaterials 6, no. 4 (2019): 211–19. http://dx.doi.org/10.1093/rb/rbz013.

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Abstract Osteoarthritis (OA) of the knee joint is a degenerative disease initiated by mechanical stress that affects millions of individuals. The disease manifests as joint damage and synovial inflammation. Post-traumatic osteoarthritis (PTOA) is a specific form of OA caused by mechanical trauma to the joint. The progression of PTOA is prevented by immediate post-injury therapeutic intervention. Intra-articular injection of anti-inflammatory therapeutics (e.g. corticosteroids) is a common treatment option for OA before end-stage surgical intervention. However, the efficacy of intra-articular i

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Simpson, Jeremy A., Keith R. Brunt, Christine P. Collier, and Steve Iscoe. "Hyperinflation-induced cardiorespiratory failure in rats." Journal of Applied Physiology 107, no. 1 (2009): 275–82. http://dx.doi.org/10.1152/japplphysiol.91342.2008.

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We previously showed that severe inspiratory resistive loads cause acute (<1 h) cardiorespiratory failure characterized by arterial hypotension, multifocal myocardial infarcts, and diaphragmatic fatigue. The mechanisms responsible for cardiovascular failure are unknown, but one factor may be the increased ventricular afterload caused by the large negative intrathoracic pressures generated when breathing against an inspiratory load. Because expiratory threshold loads increase intrathoracic pressure and decrease left ventricular afterload, we hypothesized that anesthetized rats forced to brea

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Xue, Liang, Yuning Fu, and Hilary R. Martens. "Seasonal hydrological loading in the Great Lakes region detected by GNSS: a comparison with hydrological models." Geophysical Journal International 226, no. 2 (2021): 1174–86. http://dx.doi.org/10.1093/gji/ggab158.

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SUMMARY Crustal deformation caused by hydrological processes has long been detected using space geodetic techniques, yet questions remain about the relative contributions of surface water and groundwater to the geodetic signals in different regions. Here, we investigate forward models of elastic loading deformation caused by a variety of water-storage changes within the Great Lakes region, including fluctuations in lake-water volume, soil moisture and snow load. We use lake-level data from the Great Lakes Environmental Research Laboratory, soil-moisture content from the North American Land Dat

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Di Giacomo, Giovanni, Jorge Silva, Rodrigo Martines, and Sergio Ajzen. "Computer-designed selective laser sintering surgical guide and immediate loading dental implants with definitive prosthesis in edentulous patient: A preliminary method." European Journal of Dentistry 08, no. 01 (2014): 100–106. http://dx.doi.org/10.4103/1305-7456.126257.

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ABSTRACT Objective: The aim of this study was to analyze a preliminary method of immediately loading dental implants and a definitive prosthesis based on the computer-aided design/computer-aided manufacturing systems, after 2 years of clinical follow-up. Materials and Methods: The study comprised one patient in good general health with edentulous maxilla. Cone beam computer tomography (CBCT) was performed using a radiographic template. The surgical plan was made using the digital imaging and communications in medicine protocol with ImplantViewer (version 1.9, Anne Solutions, Sao Paulo, SP, Bra

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Seracino, R., D. J. Oehlers, and M. F. Yeo. "Behaviour of Stud Shear Connectors Subjected to Bi-Directional Cyclic Loading." Advances in Structural Engineering 6, no. 1 (2003): 65–75. http://dx.doi.org/10.1260/136943303321625748.

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Almost all stud shear connectors in composite steel-concrete bridge beams are subjected to bi-directional cyclic loading at some stage during the fatigue life of the structure. In the assessment of an existing structure, it is desirable to predict the extent of fatigue damage experienced by the stud shear connectors as accurately as possible as this component of the structure can not be visually inspected. However, very little research has been carried out to quantify the fatigue behaviour of stud shear connectors subjected to bi-directional cyclic loading. This paper presents a new push-pull

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Kellis, Eleftherios, Andreas Zafeiridis, and Ioannis G. Amiridis. "Muscle Coactivation Before and After the Impact Phase of Running Following Isokinetic Fatigue." Journal of Athletic Training 46, no. 1 (2011): 11–19. http://dx.doi.org/10.4085/1062-6050-46.1.11.

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Abstract Context: The effects of fatigue on impact loading during running are unclear, with some authors reporting increased impact forces and others reporting decreased forces. Objective: To examine the effects of isokinetic fatigue on muscle cocontraction ratios about the knee and ankle during running. Design: Cross-sectional study. Setting: Neuromechanics laboratory. Patients or Other Participants: Female middle-distance runners (age = 21.3 ± 1.93 years) with at least 5 years of training experience. Intervention(s): Participants ran on the treadmill at 3.61 m/s before and immediately after

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Wakida, Masanori, Koji Ohata, Yu Hashiguchi, Kimihiko Mori, Kimitaka Hase, and Shigehito Yamada. "Immediate Effect on Ground Reaction Forces Induced by Step Training Based on Discrete Skill during Gait in Poststroke Individuals: A Pilot Study." Rehabilitation Research and Practice 2020 (May 19, 2020): 1–8. http://dx.doi.org/10.1155/2020/2397374.

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Background/Aim. Improving walking ability, especially the step-to-step transition control, is important in individuals after stroke. Although walking is a continuous skill, the discrete skills of gait, defined as movements with a clear beginning and end, may effectively modify walking performance. This pilot study shows the immediate effects of a discrete skill-based step training on ground reaction forces (GRFs) during gait in individuals with chronic hemiplegia following stroke. Methods. Twenty-two community-dwelling patients with chronic hemiplegia participated in this study. Eight particip

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Eastwood, P. R., D. R. Hillman, and K. E. Finucane. "Ventilatory responses to inspiratory threshold loading and role of muscle fatigue in task failure." Journal of Applied Physiology 76, no. 1 (1994): 185–95. http://dx.doi.org/10.1152/jappl.1994.76.1.185.

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To examine respiratory muscle recruitment pattern during inspiratory loading and role of fatigue in limiting endurance, we studied seven normal subjects on 17 +/- 6 days during breathing against progressive inspiratory threshold load. Threshold pressure (Pth) was progressively increased 14 +/- 5 cmH2O every 2 min until voluntary cessation (task failure). Subjects could adopt any breathing pattern. Tidal volume (VT), chest wall motion, end-tidal PCO2, and arterial O2 saturation were measured. At moderate loads [50–75% of maximum Pth (Pthmax)], inspiratory time (TI) decreased and VT/TI and expir

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Badr, M. S., J. B. Skatrud, J. A. Dempsey, and R. L. Begle. "Effect of mechanical loading on expiratory and inspiratory muscle activity during NREM sleep." Journal of Applied Physiology 68, no. 3 (1990): 1195–202. http://dx.doi.org/10.1152/jappl.1990.68.3.1195.

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We investigated the effect of acute and sustained inspiratory resistive loading (IRL) on the activity of expiratory abdominal muscles (EMGab) and the diaphragm (EMGdi) and on ventilation during wakefulness and non-rapid-eye-movement (NREM) sleep in healthy subjects. EMGdi and EMGab were measured with esophageal and transcutaneous electrodes, respectively. During wakefulness, EMGdi increased in response to acute loading (18 cmH2O.l-1.s) (+23%); this was accompanied by preservation of tidal volume (VT) and minute ventilation (VE). During NREM sleep, no augmentation was noted in EMGdi or EMGab. I

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Gohin, Stephanie, Behzad Javaheri, Mark Hopkinson, Andrew Anthony Pitsillides, Timothy R. Arnett, and Chantal Chenu. "Applied mechanical loading to mouse hindlimb acutely increases skeletal perfusion and chronically enhanced vascular porosity." Journal of Applied Physiology 128, no. 4 (2020): 838–46. http://dx.doi.org/10.1152/japplphysiol.00416.2019.

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Blood supply is essential for osteogenesis, yet its relationship to load-related increases in bone mass is poorly defined. Herein, we aim to investigate the link between load-induced osteogenesis and the blood supply (bone perfusion and vascular porosity) using an established osteogenic noninvasive model of axial loading. Accordingly, 12 N mechanical loads were applied to the right tibiae of six male C57BL6 mice at 10–12 wk of age, 3 times/wk for 2 wk. Skeletal perfusion was measured acutely (postloading) and chronically in loaded and contralateral, nonloaded hindlimbs by laser-Doppler imaging

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Raoof, M., and T. J. Davies. "End fixity to spiral strands undergoing cyclic bending." Journal of Strain Analysis for Engineering Design 40, no. 2 (2005): 129–37. http://dx.doi.org/10.1243/030932405x7746.

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Based on a semi-empirical approach and guided by the previously reported experimental observations and theoretical work by the first author, it is suggested that for spiral strands with mean axial strains εc > 0.0025 and outside diameters d ≤ 40 mm, plane-section bending may reasonably be assumed in the course of theoretically determining the deflected shape, of the strands in the immediate vicinity of fixed end(s) with the proviso that, at the assumed ideal fixed end(s) to the spiral strands, ρ/d > 630, where ρ is the estimated minimum radius of curvature at the fixed end. It is also sh

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Iacona, Gwenllian D., Hugh P. Possingham, and Michael Bode. "Waiting can be an optimal conservation strategy, even in a crisis discipline." Proceedings of the National Academy of Sciences 114, no. 39 (2017): 10497–502. http://dx.doi.org/10.1073/pnas.1702111114.

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Biodiversity conservation projects confront immediate and escalating threats with limited funding. Conservation theory suggests that the best response to the species extinction crisis is to spend money as soon as it becomes available, and this is often an explicit constraint placed on funding. We use a general dynamic model of a conservation landscape to show that this decision to “front-load” project spending can be suboptimal if a delay allows managers to use resources more strategically. Our model demonstrates the existence of temporal efficiencies in conservation management, which parallel

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Raza, Saim, Muhammad K. I. Khan, Scott J. Menegon, Hing-Ho Tsang, and John L. Wilson. "Strengthening and Repair of Reinforced Concrete Columns by Jacketing: State-of-the-Art Review." Sustainability 11, no. 11 (2019): 3208. http://dx.doi.org/10.3390/su11113208.

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Sustainability necessitates the protection of infrastructure from any kind of deterioration over the life cycle of the asset. Deterioration in the capacity of reinforced concrete (RC) infrastructure (e.g., bridges, buildings, etc.) may result from localised damage sustained during extreme loading scenarios, such as earthquakes, hurricanes or tsunamis. In addition, factors such as the corrosion of rebars or ageing may also deteriorate or degrade the capacity of an RC column, thereby necessitating immediate strengthening to either extend or ensure its design life is not limited. The aim of this

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Paranque, Armand-Régis, Marc Steve, Lydia Vazquez, Alain Bolleyn, Marie-Andrée Roze-Pellat, and David M. Dohan Ehrenfest. "Esthetic and Functional Reconstruction of the Posttumoral Interrupted Mandible With Double-Barrel Fibular Free Flap Graft: Rationale for a Microsurgical and Prosthodontic Approach." Journal of Oral Implantology 37, no. 5 (2011): 571–77. http://dx.doi.org/10.1563/aaid-joi-d-10-00060.

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Reconstruction after substantial osseous, cutaneous, and muscular tissue loss following a mandibular resection is a challenge. The use of a fibular free flap is an outstanding, but delicate, treatment option. These grafts, using the double-barrel technique, can achieve an almost complete reconstruction of the mandibular defect. The challenge posed by these treatments is to achieve an end result that is both functional and esthetically pleasing—an endeavor that requires a defined prosthetic plan prior to complete microsurgical reconstruction. Using a detailed clinical case, this article discuss

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Giampá, Sara Quaglia de Campos, Jorge Fernando Tavares de Souza, Marco Túlio de Mello, Sergio Tufik, Ronaldo Vagner Thomatieli dos Santos, and Hanna Karen Moreira Antunes. "MAXIMUM EFFORT TRAINING PERFORMED IN HYPOXIA ALTERS THE MOOD PROFILE." Revista Brasileira de Medicina do Esporte 24, no. 6 (2018): 440–45. http://dx.doi.org/10.1590/1517-869220182406133712.

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ABSTRACT Introduction: Physical exercise at high altitude has become constant. However, the risks associated with this type of exercise represent a major concern, considering the influence of important stressors such as hypoxia and physical exercise on psychobiological and physiological responses. Objective: Analyze the mood state and behavior of physiological variables of volunteers subjected to a progressive loading protocol until they reached maximum volitional exhaustion, both at sea level and at a simulated altitude of 4500 meters. Method: For both conditions studied, the volunteers respo

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Poon, C. S., S. A. Ward, and B. J. Whipp. "Influence of inspiratory assistance on ventilatory control during moderate exercise." Journal of Applied Physiology 62, no. 2 (1987): 551–60. http://dx.doi.org/10.1152/jappl.1987.62.2.551.

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In five healthy subjects, we studied the effects of controlled mechanical unloading of the respiratory system on ventilatory control during moderate exercise, utilizing a modified positive-pressure ventilator (IEEE Trans. Biomed. Eng. BME-33: 361–365, 1986). We were especially interested in whether isocapnia was maintained when a portion of the normal ventilatory response to constant-load cycling was subserved by the ventilator. The mechanical unloading was achieved by “assisting” airflow throughout inspiration in a constant proportion to instantaneous flow. Two modest degrees of assistance (A

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Jilma-Stohlawetz, Petra, Paul Knöbl, James C. Gilbert, and Bernd Jilma. "The anti-von Willebrand factor aptamer ARC1779 increases von Willebrand factor levels and platelet counts in patients with type 2B von Willebrand disease." Thrombosis and Haemostasis 108, no. 08 (2012): 284–90. http://dx.doi.org/10.1160/th11-12-0889.

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SummaryBlockade of hyperactive von Willebrand factor (VWF) by ARC1779 blunted the platelet drop induced by desmopressin in patients with type 2B von Willebrand disease (VWD). Thus, we hypothesised that ARC1779 may increase VWF levels and correct thrombocytopenia. Three thrombocytopenic patients suffering from type 2B VWD received a loading dose of 0.23 mg/kg ARC1779 followed by 4 μg/kg/min intravenously for 72 hours in a prospective clinical trial. ARC1779 was well tolerated and safe. Plasma concentrations of ARC1779 increased to 76 μg/ml (59–130) leading to an immediate decrease of free VWF A

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Yokouchi, Hajime, and Yoshimitsu Ohashi. "Repairing and Recovering Structural Performance of Earthen Walls Used in Japanese Dozo-Style Structures After Seismic Damage." Journal of Disaster Research 13, no. 7 (2018): 1333–44. http://dx.doi.org/10.20965/jdr.2018.p1333.

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Several traditional building group districts exist in Japan as a system for preserving the remaining historical villages and townscapes of the country, along with their surrounding environment. In the northern Kanto region of Japan, there remain examples of many dozo-style structures called “Dozo-dukuri,” forming a distinctive historical townscape. In the 2011 Tohoku Region Pacific Offshore Earthquake, the traditional townscapes and dozo-style structures of the Kanto region were seriously damaged. When restoring the walls of damaged dozo-style structures to a sound condition, demolishing and r

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Sun, Cong, Jinxiu Zhao, Chen Jianghao, and Tao Hong. "Effect of Heavy Smoking on Dental Implants Placed in Male Patients Posterior Mandibles: A Prospective Clinical Study." Journal of Oral Implantology 42, no. 6 (2016): 477–83. http://dx.doi.org/10.1563/aaid-joi-d-16-00078.

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The objective of this study was to evaluate the implant stability and peri-implant tissue response in heavy smokers receiving dental implants due to partially edentulous posterior mandibles. Forty-five ITI Straumann dental implants were placed into the partially edentulous posterior mandibles of 16 heavy smokers and 16 nonsmokers. One implant in each patient was evaluated for implant stability after surgery and before loading, and for the modified plaque index (mPLI), modified sulcus bleeding index (mSBI), probing depth (PD), and marginal bone loss (MBL) after loading. Meanwhile, the osteogeni

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Schmidt, Christoph, Carl Roosens, Michel Struys, et al. "Contractility in Humans after Coronary Artery Surgery." Anesthesiology 91, no. 1 (1999): 58–70. http://dx.doi.org/10.1097/00000542-199907000-00012.

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Background Propofol's unique pharmacokinetic profile offers advantages for titration and rapid emergence in patients after coronary artery bypass graft (CABG) surgery, but concern for negative inotropic properties potentially limits its use in these patients. The current study analyzed the effect of various propofol plasma concentrations on left ventricular (LV) contractility by means of a single-beat contractile index based on LV maximal power (PWR(max)). Methods The study was conducted in 30 patients after CABG surgery. Immediately after admission to the intensive care unit (ICU), four diffe

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Tang, J., B. Zhang, C. Gao, and H. Zepp. "Subsurface lateral flow from hillslope and its contribution to nitrate loading in the streams during typical storm events in an agricultural catchment." Hydrology and Earth System Sciences Discussions 8, no. 2 (2011): 4151–93. http://dx.doi.org/10.5194/hessd-8-4151-2011.

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Abstract. Compared with overland flow from agricultural hillslopes, subsurface lateral flow is often overlooked partly due to monitoring difficulties and the lack of quantitative identification its role in nutrient delivery to surface water. The objectives of this study were to examine how subsurface lateral flow generates from hillslopes to streams and to quantify its contribution to nutrient loading in streams. Hillslope hydrology and stream hydrology were simultaneously monitored during two typical storms and subsurface flow was separated by chemical mixing model. Positive soil water potent

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Weng, Li-Jun, Xian-Wen Hu, Yun Li, Shi-Yun Jin, Rui Li, and Ye Zhang. "Intraocular Pressure Elevation During Laparoscopic Hysterectomy of Patients in the Steep Trendelenburg Position Under Propofol Anesthesia." Journal of Medical Imaging and Health Informatics 9, no. 2 (2019): 297–302. http://dx.doi.org/10.1166/jmihi.2019.2620.

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Objective: To evaluate the intraocular pressure (IOP) during laparoscopic hysterectomy of patients in the steep trendelenburg (ST) position under propofol anesthesia. Methods: Seventy female patients, without history of ocular pathology, undergoing elective laparoscopic hysterectomy, were randomly assigned to control (Con) group or dexmedetomidine (Dex) group. The Dex group was treated with a loading dose of Dex (1 μg/kg), infusing intravenously over 15 min, followed by continuous infusion of Dex (0.4 μg/kg/h) until the end of procedure. The Con group received an equal volume of normal saline.

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Weng, Li-Jun, Xian-Wen Hu, Yun Li, Shi-Yun Jin, Rui Li, and Ye Zhang. "Intraocular Pressure Elevation During Laparoscopic Hysterectomy of Patients in the Steep Trendelenburg Position Under Propofol Anesthesia." Journal of Medical Imaging and Health Informatics 9, no. 2 (2019): 297–302. http://dx.doi.org/10.1166/jmihi.2019.2620297.

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Objective: To evaluate the intraocular pressure (IOP) during laparoscopic hysterectomy of patients in the steep trendelenburg (ST) position under propofol anesthesia. Methods: Seventy female patients, without history of ocular pathology, undergoing elective laparoscopic hysterectomy, were randomly assigned to control (Con) group or dexmedetomidine (Dex) group. The Dex group was treated with a loading dose of Dex (1 μg/kg), infusing intravenously over 15 min, followed by continuous infusion of Dex (0.4 μg/kg/h) until the end of procedure. The Con group received an equal volume of normal saline.

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Hanumanthappa, Prakashappa Thamalehally, Bharath Raja B. S., and Muthu Kishore Marichamy. "Radiological outcomes of AO type B and C distal radius fractures managed with 2.7 mm volar locking plate fixation in geriatric population: a retrospective analysis." International Journal of Research in Orthopaedics 7, no. 4 (2021): 768. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20212419.

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<p class="abstract"><strong>Background:</strong> Distal end radius fractures are one of the most common fractures. Compared to younger patients, elderly with distal radius fractures with osteoporosis and higher comminution compromise the treatment outcomes. Anatomic reduction with stable fixation is usually the choice of treatment for displaced intra-articular fractures. While osteoporosis and poor bone quality hamper fracture stabilization, locking compression plates (LCPs) provide enhanced stability and axial loading force as compared to conventional plates. The current stu

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Chang, Nai-Jen, Kuan-Wei Lee, Chih-Jou Chu, et al. "A Preclinical Assessment of Early Continuous Passive Motion and Treadmill Therapeutic Exercises for Generating Chondroprotective Effects After Anterior Cruciate Ligament Rupture." American Journal of Sports Medicine 45, no. 10 (2017): 2284–93. http://dx.doi.org/10.1177/0363546517704847.

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Background: Anterior cruciate ligament (ACL) injury is a well-known risk factor for the development of posttraumatic osteoarthritis (PTOA). However, whether using continuous passive motion (CPM) with or without additional treadmill exercise (TRE) in early ACL injury might provide chondroprotective effects and further decrease the risk of PTOA has yet to be determined. Hypothesis: CPM may offer an enhanced chondroprotective effect, but TRE may attenuate that effect due to the mechanical stress on the joint and inflammatory cytokines in the joint. Study Design: Controlled laboratory study. Metho

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Schreppers, G. J. M. A., A. A. H. J. Sauren, and A. Huson. "A Model of Force Transmission in the Tibio-Femoral Contact Incorporating Fluid and Mixtures." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 205, no. 4 (1991): 233–41. http://dx.doi.org/10.1243/pime_proc_1991_205_299_02.

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An axisymmetric finite element model is formulated which comprises a rigid spherical indentor, a meniscal ring and an articular cartilage layer, both considered as mixture materials which are interacting with an ideal fluid sub-system. From parameter studies it is concluded that the application of the mixture theory in comparison with solid modelling only leads to significant effects when the outer surfaces of the components are not sealed. The load distribution appears to change enormously during relaxation of the models. Initially the largest fraction of the load is borne by the fluid in the

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Dechman, G., M. Mishima, and J. H. Bates. "Assessment of acute pleural effusion in dogs by computed tomography." Journal of Applied Physiology 76, no. 5 (1994): 1993–98. http://dx.doi.org/10.1152/jappl.1994.76.5.1993.

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We used computed tomography (CT) to examine the effects of infusing 60 ml/kg of saline into the pleural space of four anesthetized paralyzed dogs ventilated with a constant tidal volume at a positive end-expiratory pressure of 0.5 kPa. The dogs were positioned supine, and the thoracic cavity was scanned from apex to base before and immediately after effusate loading. Each CT image was analyzed semi-automatically on a 486 personal computer with custom-designed software. We found that, despite right-side infusion, the effusate was distributed bilaterally no doubt because of the incomplete canine

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Bach, H. K., D. Orhon, O. K. Jensen, and I. S. Hansen. "Environmental model studies for the Istanbul Master Plan. Part II: water quality and eutrophication." Water Science and Technology 32, no. 2 (1995): 149–58. http://dx.doi.org/10.2166/wst.1995.0092.

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A comprehensive environmental modelling study has been carried out to support the Istanbul Master Plan Study reviewing the waste water strategy for the period up to year 2030, at which time the sewerage system is expected to be extended to serve about 20 million people. Already today the local marine areas suffer from pollution effects caused by sewage discharge. The affected areas in particular are the Bosphorus Strait and the Bosphorus Strait-Sea of Marmara junction area, which are also the natural receiving waters for the sewage from the planned new development areas of Istanbul. The genera

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Shim, Eun Yong, Soo Jin Hong, Ji-Hyun Oum, Yvonne Yanez, Yu Zhang, and Sang Eun Lee. "RSC Mobilizes Nucleosomes To Improve Accessibility of Repair Machinery to the Damaged Chromatin." Molecular and Cellular Biology 27, no. 5 (2006): 1602–13. http://dx.doi.org/10.1128/mcb.01956-06.

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ABSTRACT Repair of DNA double-strand breaks (DSBs) protects cells and organisms, as well as their genome integrity. Since DSB repair occurs in the context of chromatin, chromatin must be modified to prevent it from inhibiting DSB repair. Evidence supports the role of histone modifications and ATP-dependent chromatin remodeling in repair and signaling of chromosome DSBs. The key questions are, then, what the nature of chromatin altered by DSBs is and how remodeling of chromatin facilitates DSB repair. Here we report a chromatin alteration caused by a single HO endonuclease-generated DSB at the

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Yamada, Hiroyuki, Midori Hotta, and Nagahisa Ogasawara. "Effect of Displacement Rate on Sharp Millimeter Indentation." Key Engineering Materials 715 (September 2016): 111–15. http://dx.doi.org/10.4028/www.scientific.net/kem.715.111.

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Indentation is widely used to investigate the elastic and plastic properties of materials, which include strain rate dependence. However, the results of the general micro-indentation test were affected by the microscopic scale of materials (e.g., surface roughness, and crystal grain size distribution), since the displacement was small. In the present study, we develop the sharp millimeter indention expanded displacement without the microscopic scale of materials. Furthermore, the effect of displacement rate on the sharp millimeter indentation was evaluated using the quasi-static and impact ind

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Paterson, N., A. Tawn, K. Williams, and A. D. Nurse. "On the numerical modelling of laser shearing of glass sheets used to optimize production methods." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 218, no. 1 (2004): 1–11. http://dx.doi.org/10.1243/095440604322786901.

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The problem of the control of the propagating crack tip during laser shearing (or zero width laser cutting of glass) is essentially one of controlling the stress field within the substrate. The glass substrate is stressed thermally using surface absorption of 10.6 μm laser radiation followed by cooling, in this case from a fine atomized waterjet. The stresses created in a large sheet, combined with the residual stresses within the glass substrate, are sufficient to propagate a subsurface flaw to form a controlled crack that gives excellent cut quality. This process has previously been studied

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Nickerson, William C., Nagaraja Iyyer, Keith Legg, and Mehdi Amiri. "Modeling galvanic coupling and localized damage initiation in airframe structures." Corrosion Reviews 35, no. 4-5 (2017): 205–23. http://dx.doi.org/10.1515/corrrev-2017-0025.

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AbstractTraditionally, airframe structures are designed for immediate mechanical performance and loads-only structural response; the lifetime of aircraft structures is predicted on these analyses and environmental degradation of properties over the life cycle and during operations is often an afterthought. Although the maintenance of aircraft structures is primarily determined by material degradation, galvanic management of airframe designs and corrosion-resistant material selection have never been done systematically. From end-of-life tear-down inspections, we know that, predominantly, struct

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McBeck, Jessica A., Wenlu Zhu, and François Renard. "The competition between fracture nucleation, propagation, and coalescence in dry and water-saturated crystalline rock." Solid Earth 12, no. 2 (2021): 375–87. http://dx.doi.org/10.5194/se-12-375-2021.

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Abstract. The continuum of behavior that emerges during fracture network development in crystalline rock may be categorized into three end-member modes: fracture nucleation, isolated fracture propagation, and fracture coalescence. These different modes of fracture growth produce fracture networks with distinctive geometric attributes, such as clustering and connectivity, that exert important controls on permeability and the extent of fluid–rock interactions. To track how these modes of fracture development vary in dominance throughout loading toward failure and thus how the geometric attribute

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Oordt, Andrew J., Gerilyn S. Soreghan, Lars Stemmerik, and Linda A. Hinnov. "A record of dust deposition in northern, mid-latitude Pangaea during peak icehouse conditions of the late Paleozoic ice age." Journal of Sedimentary Research 90, no. 4 (2020): 337–63. http://dx.doi.org/10.2110/jsr.2020.15.

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ABSTRACT The Wordiekammen Formation, a carbonate ramp on Spitsbergen developed on the Northern Pangaean margin in Moscovian (Carboniferous) through Sakmarian (Permian) time at a paleolatitude of 30–35° N. The study site on the Nordfjorden High was isolated from any source of fluvio-deltaic input, such that detrital material that occurs in this system experienced eolian transport, thus forming a proxy for atmospheric dust loading. We analyzed two intervals, of Moscovian (10 m) and Asselian (27 m) age, at 20 cm resolution, and identified five mid-ramp subtidal facies organized in upwardly shallo

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