Thematische Bibliographien / Iron Therapeutic use Tanzania

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  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte

Auswahl der wissenschaftlichen Literatur zum Thema „Iron Therapeutic use Tanzania“

Autor: Grafiati
Veröffentlicht am 4. Juni 2021
Zuletzt aktualisiert am 28. Januar 2023

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Zeitschriftenartikel zum Thema "Iron Therapeutic use Tanzania"

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Hatcher, Heather C., Ravi N. Singh, Frank M. Torti, and Suzy V. Torti. "Synthetic and natural iron chelators: therapeutic potential and clinical use." Future Medicinal Chemistry 1, no. 9 (December 2009): 1643–70. http://dx.doi.org/10.4155/fmc.09.121.

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Bhandari, Bharti, and Anita Mehta. "Serum iron and serum retinol level of severe acute malnourished children on therapeutic intervention with WHO/UNICEF recommended therapeutic food and home based therapeutic food." International Journal of Contemporary Pediatrics 8, no. 2 (January 22, 2021): 337. http://dx.doi.org/10.18203/2349-3291.ijcp20210125.

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Background: The prevalence of anaemia and vitamin A deficiency among children with severe acute malnutrition (SAM) and their correction during nutritional rehabilitation are not well documented. This study assessed serum iron and serum retinol levels, effect of ready-to-use therapeutic foods (RUTF) and home based treatment on levels of serum iron and serum retinol level in SAM children.Methods: This was a simple randomised controlled trial in 6-59 months old children with SAM. Two groups of 70 each were divided, one was given RUTF and other home based food comparable to RUTF. Serum retinol and
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Boshuizen, M., K. van der Ploeg, L. von Bonsdorff, B. J. Biemond, S. S. Zeerleder, R. van Bruggen, and N. P. Juffermans. "Therapeutic use of transferrin to modulate anemia and conditions of iron toxicity." Blood Reviews 31, no. 6 (November 2017): 400–405. http://dx.doi.org/10.1016/j.blre.2017.07.005.

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Makis, Alexandros, Ersi Voskaridou, Ioannis Papassotiriou та Eleftheria Hatzimichael. "Novel Therapeutic Advances in β-Thalassemia". Biology 10, № 6 (18 червня 2021): 546. http://dx.doi.org/10.3390/biology10060546.

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The main characteristic of the pathophysiology of β-thalassemia is reduced β-globin chain production. The inevitable imbalance in the α/β-globin ratio and α-globin accumulation lead to oxidative stress in the erythroid lineage, apoptosis, and ineffective erythropoiesis. The result is compensatory hematopoietic expansion and impaired hepcidin production that causes increased intestinal iron absorption and progressive iron overload. Chronic hemolysis and red blood cell transfusions also contribute to iron tissue deposition. A better understanding of the underlying mechanisms led to the detection
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Islam, Sufia, Nazia Hoque, Nishat Nasrin, Mehnaz Hossain, Farhana Rizwan, Kushal Biswas, Muhammad Asaduzzaman, et al. "Iron Overload and Breast Cancer: Iron Chelation as a Potential Therapeutic Approach." Life 12, no. 7 (June 27, 2022): 963. http://dx.doi.org/10.3390/life12070963.

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Breast cancer has historically been one of the leading causes of death for women worldwide. As of 2020, breast cancer was reported to have overtaken lung cancer as the most common type of cancer globally, representing an estimated 11.3% of all cancer diagnoses. A multidisciplinary approach is taken for the diagnosis and treatment of breast cancer that includes conventional and targeted treatments. However, current therapeutic approaches to treating breast cancer have limitations, necessitating the search for new treatment options. Cancer cells require adequate iron for their continuous and rap
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Casu, Carla, and Stefano Rivella. "Iron age: novel targets for iron overload." Hematology 2014, no. 1 (December 5, 2014): 216–21. http://dx.doi.org/10.1182/asheducation-2014.1.216.

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Abstract Excess iron deposition in vital organs is the main cause of morbidity and mortality in patients affected by β-thalassemia and hereditary hemochromatosis. In both disorders, inappropriately low levels of the liver hormone hepcidin are responsible for the increased iron absorption, leading to toxic iron accumulation in many organs. Several studies have shown that targeting iron absorption could be beneficial in reducing or preventing iron overload in these 2 disorders, with promising preclinical data. New approaches target Tmprss6, the main suppressor of hepcidin expression, or use mini
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Sohn, Yang-Sung, William Breuer, Arnold Munnich, and Z. Ioav Cabantchik. "Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications." Blood 111, no. 3 (February 1, 2008): 1690–99. http://dx.doi.org/10.1182/blood-2007-07-102335.

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AbstractVarious pathologies are characterized by the accumulation of toxic iron in cell compartments. In anemia of chronic disease, iron is withheld by macrophages, leaving extracellular fluids iron-depleted. In Friedreich ataxia, iron levels rise in the mitochondria of excitable cells but decrease in the cytosol. We explored the possibility of using deferiprone, a membrane-permeant iron chelator in clinical use, to capture labile iron accumulated in specific organelles of cardiomyocytes and macrophages and convey it to other locations for physiologic reuse. Deferiprone's capacity for shuttlin
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Torshin, I. Yu, and O. A. Gromova. "Worldwide experience of the therapeutic use of the human placental hydrolytes." Experimental and Clinical Gastroenterology 1, no. 10 (March 2, 2020): 79–89. http://dx.doi.org/10.31146/1682-8658-ecg-170-10-79-89.

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Here we present the results of a systematic analysis of publications on the clinical and the experimental pharmacology of human placental hydrolyzates (HPH). Searches were performed in the PUBMED, ELIBRARY and RSL databases. The results of the analyses of the peptide composition of HPH allowed us to formulate a number of previously unknown molecular mechanisms of their action. In the article we examine the effects of HPH in the therapy of liver diseases, atopic dermatitis, herpetic infection, viral hepatitis, joint diseases, iron overload, chronic fatigue syndrome and consider the general rege
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Scott, Cassidy, Gaurav Arora, Kayle Dickson, and Christian Lehmann. "Iron Chelation in Local Infection." Molecules 26, no. 1 (January 2, 2021): 189. http://dx.doi.org/10.3390/molecules26010189.

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Iron is an essential element in multiple biochemical pathways in humans and pathogens. As part of the innate immune response in local infection, iron availability is restricted locally in order to reduce overproduction of reactive oxygen species by the host and to attenuate bacterial growth. This physiological regulation represents the rationale for the therapeutic use of iron chelators to support induced iron deprivation and to treat infections. In this review paper we discuss the importance of iron regulation through examples of local infection and the potential of iron chelation in treating
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Moscheo, Carla, Elisa Fenizia, Mariaclaudia Meli, and Giovanna Russo. "Anemia sideropenica in età pediatrica: pillole di… ferro." QUADERNI ACP 28, no. 4 (2021): 173. http://dx.doi.org/10.53141/qacp.2021.176-180.

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Iron deficiency anemia is the most frequent haematological disorder in children. Although much is already known about the diagnostic-therapeutic approach, new frontiers regarding its diagnosis and therapeutic options emerge every day. An adequate intake with the diet is essential and can also be obtained in compliance with vegetarian-type diets. The use of glycinate or lysosomal preparations could positively affect the efficacy of therapy reducing the side effects associated with commonly used iron preparations. Parenteral iron therapy in pediatric age, which is currently limited to selected c
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Dissertationen zum Thema "Iron Therapeutic use Tanzania"

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Mwanri, Lillian. "Impact of vitamin A and iron on anaemia and cognitive functioning of anaemic school children in Tanzania." Title page, table of contents and summary only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phm994.pdf.

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Mouralian, Cindy. "Evaluation of novel iron chelators for therapeutic use in secondary iron overload disorders." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33071.

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Pyridoxal isonicotinoyl hydrazone (PIH) has been described as an orally effective Fe chelator. It is both membrane permeable and plasma soluble, and has a high affinity for Fe, making it an ideal model on which to base future chelators. Ten novel ligands have been synthesized based on these attributes. Characterization experiments were performed to determine the ligands' selectivity and binding affinity for iron, their lipophilicity as both free and Fe-ligand complexes, and their stoichiometric relationship with iron. Efficacy of the chelators has been determined through their ability to effec
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Li, Niya, and 李妮婭. "Meta-analysis of the safety of iron chelating agents." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208520.

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Background: Thalassaemia is a genetic disorder disease, one of the most clinically relevant haemoglobinopathies in paediatric population. It interferes with the synthesis of haemoglobin chain. For the sake of maintaining the serum haemoglobin at a normal level, regular blood cell transfusion is required to the patients with thalassaemia. In general, patients with thalassaemia are often diagnosed at an early age and need to take a life-long iron chelating therapy to prevent the multi-organ failure caused by iron-overload. The safety issue is considered a very importance aspect in the treatmen
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Sarmento, Carlos V. 1980. "Assessment of new iron chelating agents for treatment of iron-overload." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116063.

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Patients with acquired iron overload require chelation therapy using either Desferal or Exjade. Iron in excess may promote free radical formation in the Fenton reaction resulting in severe injuries of heart, liver and endocrine organs. Che1ators that bind ferric iron (Fe+3) in a 1:1 complex (Desferal) sequester it more efficiently than those che1ators that form 2:1 (Exjade) complexes. We initiated synthesis of new chelators derived from the tridentate chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogs. The aim of the synthesis was to generate chelators that bind iron in a 1:1 com
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Wong, Lai-Ming Ella, and 黃禮明. "Iron and ruthenium complexes with nitrogen and oxygen donor ligands for anti-cancer and anti-viral studies." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B3587742X.

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Mwanri, Lillian. "Impact of vitamin A and iron on anaemia and cognitive functioning of anaemic school children in Tanzania / Lillian Mwanri." Thesis, 2001. http://hdl.handle.net/2440/21747.

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Mukaya, Hembe Elie. "Macromolecular antineoplastic iron and platinum co-ordination compounds." Thesis, 2014.

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A thesis submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in fulfillment of the requirements for the degree of Doctor of Philosophy of Science. Johannesburg, 2013<br>Chemotherapy, while representing a vital component of cancer treatment modalities, has so far not fulfilled basic expectations with unsatisfactory cure rates and frequent relapse due to limited effectiveness of the therapeutic drugs, severe side effects and resistance problems. The platinumcontaining drugs used in present clinical practice are no exception to this generalized finding. Whi
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Lee, Chia-Lin. "Vitamin E and iron status in hemodialysis patients." Thesis, 2002. http://hdl.handle.net/1957/27225.

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The present study investigated whether vitamin E supplementation reduced oxidative stress in erythrocytes and improved vitamin E status in patients undergoing hemodialysis (HD). Plasma and erythrocyte α-tocopherol, plasma ascorbic acid, and iron status were determined in 11 regular HD patients prior to and post-dialysis, before and during oral supplementation of vitamin E, 400 IU daily for two months. HD patients were categorized into two groups according to their plasma ascorbic acid levels. We found that only the vitamin C sufficient group (>40 μM, Group I) had reliable measurements of eryth
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Schwendenwein, Shayne. "Idle Iron: Adaptive re-use of oil rigs into reef rehabilitation machines that decompose to form coral reef - Mtwara, Tanzania." Thesis, 2013. http://hdl.handle.net/10539/13095.

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I want to design a prototype where retired oil rigs of various types can be towed to nearby reef biodiversity areas under threat, converted into reef rehabilitators and researchers, community educators, and tourism friendly machines that will biodegrade over time to form artificial reefs. The premise is to get the communities reliant on the reef to get involved by teaching sustainable fishing methods, showing that tourism is a sustainable and growing income, spreading the word via radio and education and thus stemming the damage on reefs. During the reef’s life-span as a machine, certain par
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Bücher zum Thema "Iron Therapeutic use Tanzania"

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Irving, Holly Berry. Iron and human nutrition: Research & reference materials, 1982-1986 : 176 citations. Beltsville, Md: U.S. Dept. of Agriculture, National Agricultural Library, 1987.

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Irving, Holly Berry. Iron and human nutrition: Research and reference materials, 1983-1987 : 138 citations. Beltsville, Md: U.S. Dept. of Agriculture, National Agricultural Library, 1988.

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Mizner, Gail Elizabeth. The effects of desferrioxamine iron chelation therapy in hypertransfused beta-thalassemia patients. [New Haven: s.n.], 1986.

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Kim, Chong-ju. B-pyŏngdong sihwajŏn: Si chʻiryo ŭi iron kwa silche : kotʻong ŭi yuksŏng. Sŏul-si: Hana Ŭihaksa, 1989.

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1945-, Bergeron Raymond J., and Brittenham Gary M, eds. The Development of iron chelators for clinical use. Boca Raton: CRC Press, 1994.

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Kŏn'gang yaksŏn chori: Iron mit silsŭp = Health food based on Oriental medicinal theory. Kyŏnggi-do P'aju-si: Chigu Munhwasa, 2011.

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Christos, Kattamis, ed. Iron overload and chelation in thalassaemia: A symposium held during the 2nd International Conference on Thalass[a]emia and the Hemoglobinopathies, Herakleion, Crete, 1987. Toronto: H. Huber Publishers, 1989.

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Workshop for Reviewing the Salt Regulations (2003 Kibaha, Tanzania). Prevention and control of iodine deficiency disorders in Tanzania: Proceedings of the Workshop for Reviewing the Salt Regulations : held at Njuweni Hotel, Kibaha, 5th-7th February 2003. [Dar es Salaam]: NCCIDD, 2003.

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R, Tatala S., Shirika la Chakula Bora Tanzania., and Chalmers tekniska hogskola. Dept. of Food Science., eds. Prevalence of iron deficiency anaemia in preschool children and the effect of vitamin C supplementation: A study carried out in Msoga Village, Coast Region, Tanzania, 1992/1993. Dar es Salaam, Tanzania: Tanzania Food and Nutrition Centre, 1993.

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(Editor), David G. Badman, Raymond J. Bergeron (Editor), and Gary M. Brittenham (Editor), eds. Iron Chelators: New Development Strategies. Saratoga Group, 2000.

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Buchteile zum Thema "Iron Therapeutic use Tanzania"

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Templeton, D. M. "Therapeutic Use of Chelating Agents in Iron Overload." In Toxicology of Metals, 305–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79162-8_14.

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"3. IRON CHELATION FOR IRON OVERLOAD IN THALASSEMIA." In Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic, 49–86. De Gruyter, 2019. http://dx.doi.org/10.1515/9783110527872-003.

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"5. INFECTIONS ASSOCIATED WITH IRON ADMINISTRATION." In Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic, 123–56. De Gruyter, 2019. http://dx.doi.org/10.1515/9783110527872-005.

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"6. IRON OXIDE NANOPARTICLE FORMULATIONS FOR SUPPLEMENTATION." In Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic, 157–80. De Gruyter, 2019. http://dx.doi.org/10.1515/9783110527872-006.

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Farag, Mayada R., Mahmoud Alagawany, Mohamed E. Abd El-Hack, Sameh A. Abdelnour, Kuldeep Dhama, Ayman A. Swelum, and Alessandro Di Cerbo. "Dandelion Herb: Chemical Composition and Use in Poultry Nutrition." In Antibiotic Alternatives in Poultry and Fish Feed, 124–36. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049015122010012.

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Taraxacum officinale, also known as dandelion herb, is a popular medicinal and therapeutic herb used for many years and is mostly raised in Europe, Asia, North and South America. It contains several nutrients and bioactive substances, especially the leaves and roots of this herb, which are a rich source of fiber, lecithin, choline, and micronutrients such as minerals (potassium, magnesium, calcium, zinc, etc., iron) and vitamins (A, C, K, and B-complex). The root has been commonly used for digestive and liver problems due to its stimulatory effects on the production of bile and detoxification functions. The leaves of dandelion have stimulatory functions on the digestive system and possess diuretic effects. Furthermore, several studies have shown that dandelion leaves can enhance the growth and productivity of poultry. Various functions on the intestinal mucosa have been reported, including the effects on the architecture of villi, villus height/crypt depth ratio, and cellular infiltration. This herb also has various beneficial functions, such as immunomodulatory effects, stimulation of the digestive system and insulin activation, enhancing the metabolism of androgens, and acting as a probiotic, antiangiogenic, antineoplastic and demulcent. Moreover, the dandelion herb can treat indigestions and hepatitis B infection. Due to the lack of studies on the effects of dandelion, further research has to be conducted to exploit the medicinal properties of this herb for its beneficial health impact on humans, pet and livestock animals (e.g., poultry) nutrition.
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Boumaiza, Mohamed, Samia Rourou, Paolo Arosio, and Mohamed Nejib Marzouki. "The Use of Ferritin as a Carrier of Peptides and Its Application for Hepcidin." In BioMechanics and Functional Tissue Engineering [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94408.

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Hepcidin a 25-amino-acid and highly disulfide bonded hormone, is the central regulator of iron homeostasis. In this chapter we propose ferritin as a peptide carrier to promote the association of the hybrid hepcidin/ferritin nanoparticle with a particular cell or tissue for therapeutic or diagnostic use. Indeed, human ferritin H-chain fused directly (on its 5’end) with camel mature hepcidin was cloned into the pASK-43 plus vector and expressed using BL21 (DE3) pLys E. coli strain. The transformed E.coli produced efficiently hepcidin-ferritin construct (hepcH), consisting of 213 amino acids with a molecular weight of 24 KDa. The recovered product is a ferritin exposing hepcidin on outer surface. The hepcH monomer was characterized by immunoblotting using a monoclonal antibody specific for human ferritin and a polyclonal antibody specific for hepcidin-25. The results were also confirmed by MALDI-TOF mass spectrometry. The recombinant native human ferritin and the commercial human hepcidin-25 were used as controls in this experiment. The assembly of hepcH, as an heteropolymer molecule, was performed in presence of denatured human ferritin-H and -L chains. After cysteine oxidation of the recombinant nanoparticles, cellular binding assays were performed on mammalian cells such as mouse monocyte–macrophage cell line J774, HepG2 and COS7.
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Singh, Indu, Janelle Guerrero, and Michael J. Simmonds. "Developing a National Registry for Hemochromatosis." In Improving Health Management through Clinical Decision Support Systems, 154–64. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-4666-9432-3.ch007.

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Hereditary Hemochromatosis (HH) is a disorder where iron and ferritin concentrations in a patient's blood are much higher than normal healthy levels. The main therapeutic intervention for individuals with HH is removing 300-500 mL of blood every few months to maintain ferritin concentration within acceptable ranges. The blood collected during these venesections is usually discarded as there is a belief that blood with high levels of ferritin are not suitable for blood transfusion purposes. Australian Red Cross Blood Services voluntarily collects blood from donors for subsequent use in blood transfusion. Annually more than 700 thousand units are transfused within Australia and there is a constant need for new donors given the significant imbalance between supply and demand of blood products. Besides red cell transfusions, the Red Cross also issues donor blood for development of many other blood products essential for patient health care. The HH blood can currently be used for other blood products if not for red cell transfusion. However, there is evidence to suggest that there is no significant difference between the red cells of the normal healthy population compared to those from HH patients. Australian Red Cross has developed a mobile computer application (High Ferritin “app”) as they have started collecting blood from HH patients. Though there is little or no awareness about the existence and use of this High Ferritin app in general HH population, their doctors and nurses collecting their blood for therapeutic purposes. This chapter describes possibility of saving and utilizing the blood collected from hemochromatosis patients for therapeutic purposes. A national hemochromatosis patients registry, in collaboration with High Ferritin app (HFa) developed by Australian Red Cross Blood Services, accessible to the patients, their doctors and Red Cross Blood Collection Sservices 24 hours a day anywhere in the country can allow the patients to donate the blood collected for therapeutic purposes at any affiliated blood collection center in the country after they automatically get a message either by email or text message after their blood results have been reviewed by their doctor and they are required to go for venesection.
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Konferenzberichte zum Thema "Iron Therapeutic use Tanzania"

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Ristic, Bojana, Sathish Sivaprakasam, Jiro Ogura, and Vadivel Ganapathy. "Abstract 4477: Downregulation of ABCG2 expression in colitis and colon cancer: Relevance to iron overload, hemochromatosis and p53, and therapeutic use of carbidopa to reverse the downregulation." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-4477.

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Yuan, Yuan, and Diana-Andra Borca-Tasciuc. "The Influence of Coating and Agglomeration on Specific Absorption Rate of Iron Oxide Nanoparticles." In ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2011. http://dx.doi.org/10.1115/icnmm2011-58217.

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Magnetic nanofluids can be remotely heated by alternating magnetic field and have significant potential for cancer hyperthermia therapy. The heat generated by magnetic nanoparticles is typically quantified by the specific absorption rate (SAR), which represents the thermal power per unit mass of magnetic material generated in the presence of an alternating magnetic field. During hyperthermia treatment, heat dosage of tumor tissue correlates with slowing tumor growth. The therapeutic ratios of cancer can be increased with the use of biofunctionalized magnetic nanoparticles that have higher SAR
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Al-Ansari, Dana E., Nura A. Mohamed, Isra Marei, Huseyin Yalcin, and Haissam Abou-Saleh. "Assessment of Metal Organic Framework as Potential Drug Carriers in Cardiovascular Diseases." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0127.

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Background: Cardiovascular diseases (CVDs) are considered the major cause of death worldwide. Therapeutic delivery to the cardiovascular system may play an important role in the successful treatment of a variety of CVDs, including atherosclerosis, ischemic-reperfusion injury, and microvascular diseases. Despite their clinical benefits, current therapeutic drugs are hindered by their short half-life and systemic side effects. This limitation could be overcome using controlled drug release with the potential for targeted drug delivery using a nanomedicine approach. In the current study, we have
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Babarykin, Dmitry, Gaļina Smirnova, Svetlana Vasiļjeva, Anna Fedotova, Andrey Fedotov, and Natālija Basova. "Evaluation of the biological activity of sugar-free fractionated red beetroot juice." In 80th International Scientific Conference of the University of Latvia. University of Latvia, 2023. http://dx.doi.org/10.22364/iarb.2022.05.

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In the case of type II diabetes, the most important preventive and therapeutic effect gives a diet with a minimal amount of easily digestible carbohydrates. Vegetable juices are posi-tioned as healthy food, because of the high content of phenolic and other biologically active compounds. However, due to the high glycemic index, juices are contraindicated in obesity, and diabetes, while juices with a reduced glycemic index, are not available on the market. We have developed a technology for the fractionation of red beetroot juice based on molecular mass using ultrafiltration. The resulting fract
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