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Thematische Bibliographien / Kidney relocation / Zeitschriftenartikel

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Zeitschriftenartikel zum Thema „Kidney relocation“

Autor: Grafiati

Veröffentlicht am 7. Juni 2025

Zuletzt aktualisiert am 2. August 2025

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1

Abrol, Nitin, and NitinS Kekre. "Focused ultrasound guided relocation of kidney stones." Indian Journal of Urology 31, no. 1 (2015): 28. http://dx.doi.org/10.4103/0970-1591.139577.

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Genereux, Denise, Lida Fan, and Keith Brownlee. "The Psychosocial and Somatic Effects of Relocation from Remote Canadian First Nation Communities to Urban Centres on Indigenous Peoples with Chronic Kidney Disease (CKD)." International Journal of Environmental Research and Public Health 18, no. 7 (2021): 3838. http://dx.doi.org/10.3390/ijerph18073838.

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Chronic kidney disease, also referred to as end-stage renal disease (ESRD), is a prevalent and chronic condition for which treatment is necessary as a means of survival once affected individuals reach the fifth and final stage of the disease. Dialysis is a form of maintenance treatment that aids with kidney functioning once a normal kidney is damaged. There are two main types of dialysis: hemodialysis (HD) and peritoneal dialysis (PD). Each form of treatment is discussed between the patient and nephrologist and is largely dependent upon the following factors: medical condition, ability to admi

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Mansi, Bhandawne Tanvi Jadhav* Hitesh Mahajan Omkar Labhade. "Immunosuppressive Drug Adherence in Kidney Relocate Patients: A Comprehensive Review." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1429–42. https://doi.org/10.5281/zenodo.15031749.

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Rebelliousness with immunosuppressive meds, after renal transplantation is accepted to be a significant reason for allograft dismissal and unite misfortune, with the great expenses of these specialists, thought about a huge justification for resistance. Our motivation was to decide the consistency paces of renal transfer patients who accepted their immunosuppressant treatment for nothing and assess their examples of consistency.All patients who got a renal transfer and accepted their immunosuppressant drugs at our foundation for their most memorable year post-transplant were remembered for the

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Rowart, P., P. Erpicum, J. M. Krzesinski, M. Sebbagh, and F. Jouret. "Mesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1." Stem Cells International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/9717353.

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Background. Mesenchymal stromal cells (MSC) are fibroblast-like multipotent cells capable of tissue-repair properties. Given the essentiality of tight junctions (TJ) in epithelial integrity, we hypothesized that MSC modulate TJ formation, via the AMP-activated kinase (AMPK) pathway. Liver kinase-β1 (LKB1) and Ca2+-calmodulin-dependent protein kinase kinase (CaMKK) represent the main kinases that activate AMPK.Methods. The in vitro Ca2+switch from 5 μM to 1.8 mM was performed using epithelial Madin-Darby canine kidney (MDCK) cells cultured alone or cocultured with rat bone marrow-derived MSC or

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Scholes-Robertson, Nicole Jane, Talia Gutman, Martin Howell, et al. "Clinicians’ perspectives on equity of access to dialysis and kidney transplantation for rural people in Australia: a semistructured interview study." BMJ Open 12, no. 2 (2022): e052315. http://dx.doi.org/10.1136/bmjopen-2021-052315.

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ObjectivesPeople with chronic kidney disease requiring dialysis or kidney transplantation in rural areas have worse outcomes, including an increased risk of hospitalisation and mortality and encounter many barriers to accessing kidney replacement therapy. We aim to describe clinicians’ perspectives of equity of access to dialysis and kidney transplantation in rural areas.DesignQualitative study with semistructured interviews.Setting and participantsTwenty eight nephrologists, nurses and social workers from 19 centres across seven states in Australia.ResultsWe identified five themes: the tyrann

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Kong, Juan, Li Han, Han Su, Yihan Hu, Xueshi Huang, and Yan Lou. "Riligustilide Attenuated Renal Injury by the Blockade of Renin." Cellular Physiology and Biochemistry 50, no. 2 (2018): 654–67. http://dx.doi.org/10.1159/000494186.

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Background/Aims: Nephropathy related with renin can be alleviated with ACE-inhibitors or AT1R blockers, whereas they might be ineffective after long-term administration because of a feedback production of enhanced renin. Therefore, it is urgent to develop a new category of anti-nephropathy medicine directly targeting renin. Riligustilide (C20), originally isolated from the Chinese herb Ligusticumporteri, a rhizome, was confirmed effective against many diseases. Methods: The therapeutic effect of C20 on renal injury and its underlying mechanism were investigated in three different nephrotic mod

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Lei, Lei, Ming Huang, Limin Su, et al. "Manganese promotes intracellular accumulation of AQP2 via modulating F-actin polymerization and reduces urinary concentration in mice." American Journal of Physiology-Renal Physiology 314, no. 2 (2018): F306—F316. http://dx.doi.org/10.1152/ajprenal.00391.2017.

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Aquaporin-2 (AQP2) is a water channel protein expressed in principal cells (PCs) of the kidney collecting ducts (CDs) and plays a critical role in mediating water reabsorption and urine concentration. AQP2 undergoes both regulated trafficking mediated by vasopressin (VP) and constitutive recycling, which is independent of VP. For both pathways, actin cytoskeletal dynamics is a key determinant of AQP2 trafficking. We report here that manganese chloride (MnCl2) is a novel and potent regulator of AQP2 trafficking in cultured cells and in the kidney. MnCl2 treatment promoted internalization and in

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Hou, Shurong, Franck Madoux, Louis Scampavia, Jo Ann Janovick, P. Michael Conn, and Timothy P. Spicer. "Drug Library Screening for the Identification of Ionophores That Correct the Mistrafficking Disorder Associated with Oxalosis Kidney Disease." SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, no. 7 (2017): 887–96. http://dx.doi.org/10.1177/2472555217689992.

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Primary hyperoxaluria is the underlying cause of oxalosis and is a life-threatening autosomal recessive disease, for which treatment may require dialysis or dual liver-kidney transplantation. The most common primary hyperoxaluria type 1 (PH1) is caused by genetic mutations of a liver-specific enzyme alanine:glyoxylate aminotransferase (AGT), which results in the misrouting of AGT from the peroxisomes to the mitochondria. Pharmacoperones are small molecules with the ability to modify misfolded proteins and route them correctly within the cells, which may present an effective strategy to treat A

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Contreras, R. G., G. Avila, C. Gutierrez, et al. "Repolarization of Na+-K+ pumps during establishment of epithelial monolayers." American Journal of Physiology-Cell Physiology 257, no. 5 (1989): C896—C905. http://dx.doi.org/10.1152/ajpcell.1989.257.5.c896.

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Madin-Darby canine kidney (MDCK) cells plated at confluence and incubated for 20 h in low (5 microM) Ca2+ have no tight junctions (TJs), and their Na+-K+-ATPase is randomly distributed over the surface. On transfer to normal Ca2+ levels (1.8 mM) ("Ca2+ switch"), TJs and transepithelial resistance develop quickly, trapping a considerable fraction (35%) of the surface Na+-K+-ATPase on the apical (incorrect) side. This misplaced enzyme is subsequently removed from this region or inactivated, demonstrating that polarization proceeds despite TJs. Simultaneously, the amount of Na+-K+-ATPase on the b

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Masika, Golden Mwakibo, Ansfrida Rwezaura ALFRED, and Rehema Bakari OMARI. "Adversities of Living With Renal Failure in Africa: The Lived Experiences of Patients Receiving Renal Replacement Therapy in Dodoma Tanzania." International Journal of Critical Care 18, no. 4 (2024): 36–37. https://doi.org/10.29173/ijcc1003.

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Background Chronic kidney disease (CKD) involves a progressive loss of kidney function due to damage to the epithelia and endothelia kidney cells, lasting at least 3 months (Kipp & Kellerman, 2008). It emerges as a global health concern as it affects an average of one in ten people and is listed among the top ten causes of mortality globally (Kovesdy, 2022). In Tanzania, CKD causes three times higher mortality than other diseases (Kilonzo et al., 2016). The impact of CKD on patient’s quality of life due to debilitating physical and psychological symptoms resulting from accumulation of toxi

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Sparwasser, P., S. Epple, A. Thomas, et al. "First completely robot-assisted retroperitoneal nephroureterectomy with bladder cuff: a step-by-step technique." World Journal of Urology 40, no. 4 (2022): 1019–26. http://dx.doi.org/10.1007/s00345-021-03920-1.

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Abstract Introduction While various surgical techniques have been reported for open and minimally invasive treatment of upper tract urothelial cancer (UTUC), the procedure of robot-assisted nephroureterectomy (NU) with bladder cuff has never been reported using only retroperitoneum without entering abdominal cavity. We developed a novel port placement and technique allowing to perform robot-assisted NU by a unique retroperitoneal approach. Methods Between February and June 2021 patients with history of UTUC were treated by robot-assisted NU completely restricted to retroperitoneal space using

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Ray, Gautam. "Health and social burden of alcohol use disorders in an industrial population of India." International Journal Of Community Medicine And Public Health 10, no. 4 (2023): 1561–67. http://dx.doi.org/10.18203/2394-6040.ijcmph20230942.

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Background: In the last two decades the rate of alcohol consumption has substantially increased in India but the socioeconomic burden of alcohol use disorders (AUD) is understudied. Methods: 48613 patients admitted from January 2009 to December 2018 for diseases directly or indirectly related to alcohol use (40.1% of total admission) were analysed. Retrospective analysis of prospectively maintained data was used as current study design. Diagnosis were arrived at by history, clinical examination and relevant investigations. Social data included demography, alcohol related information, social, e

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Kozlov, Yu A., S. S. Poloyan, A. A. Marchuk, et al. "FLUORESCENCE-GUIDED SURGERY. THE FIRST USE IN CHILDREN." Pediatria. Journal named after G.N. Speransky 102, no. 5 (2023): 222–30. http://dx.doi.org/10.24110/0031-403x-2023-102-5-222-230.

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Article represents the first use of fluorescence-guided surgery in pediatric patients and demonstrates procedures that can be recommended for use in children. Materials and methods used: medical records of 28 pediatric patients who underwent laparoscopic and thoracoscopic procedures under fluorescence guidance were studied. Surgical procedures were performed using Rubina® endovideosurgical system by KARL STORZ, Germany. The most frequently performed surgical procedure in childhood was laparoscopic varicocelectomy, with 10 cases where ICG navigation was used to identify testicular lymphatic ves

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Alcalde, J., P. Bonay, A. Roa, S. Vilaro, and I. V. Sandoval. "Assembly and disassembly of the Golgi complex: two processes arranged in a cis-trans direction." Journal of Cell Biology 116, no. 1 (1992): 69–83. http://dx.doi.org/10.1083/jcb.116.1.69.

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We have studied the disassembly and assembly of two morphologically and functionally distinct parts of the Golgi complex, the cis/middle and trans cisterna/trans network compartments. For this purpose we have followed the redistribution of three cis/middle- (GMPc-1, GMPc-2, MG 160) and two trans- (GMPt-1 and GMPt-2) Golgi membrane proteins during and after treatment of normal rat kidney (NRK) cells with brefeldin A (BFA). BFA induced complete disassembly of the cis/middle- and trans-Golgi complex and translocation of GMPc and GMPt to the ER. Cells treated for short times (3 min) with BFA showe

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Bulbarelli, Alessandra, Teresa Sprocati, Massimo Barberi, Emanuela Pedrazzini, and Nica Borgese. "Trafficking of tail-anchored proteins: transport from the endoplasmic reticulum to the plasma membrane and sorting between surface domains in polarised epithelial cells." Journal of Cell Science 115, no. 8 (2002): 1689–702. http://dx.doi.org/10.1242/jcs.115.8.1689.

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Tail-anchored (TA) proteins, which are defined by an N-terminal cytosolic region and a C-terminal transmembrane domain (TMD), provide useful models for studying the role of the TMD in sorting within the exo-endocytic system. Previous work has shown that a short TMD is required to keep ER-resident TA proteins from escaping to downstream compartments of the secretory pathway. To investigate the role of the TMD in TA protein sorting, we used model constructs, which consisted of GFP linked at its C-terminus to the tail region of cytochrome b(5) with TMDs of differing length or hydrophobicity. Expr

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Eguchi, Takanori, Eva Csizmadia, Hotaka Kawai, et al. "SCAND1 Reverses Epithelial-to-Mesenchymal Transition (EMT) and Suppresses Prostate Cancer Growth and Migration." Cells 11, no. 24 (2022): 3993. http://dx.doi.org/10.3390/cells11243993.

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Epithelial–mesenchymal transition (EMT) is a reversible cellular program that transiently places epithelial (E) cells into pseudo-mesenchymal (M) cell states. The malignant progression and resistance of many carcinomas depend on EMT activation, partial EMT, or hybrid E/M status in neoplastic cells. EMT is activated by tumor microenvironmental TGFβ signal and EMT-inducing transcription factors, such as ZEB1/2, in tumor cells. However, reverse EMT factors are less studied. We demonstrate that prostate epithelial transcription factor SCAND1 can reverse the cancer cell mesenchymal and hybrid E/M p

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Prichasuk, Somchai, and Opas Sinphurmsukskul. "Kidner Procedure for Symptomatic Accessory Navicular and Its Relation to Pes Planus." Foot & Ankle International 16, no. 8 (1995): 500–503. http://dx.doi.org/10.1177/107110079501600807.

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The role of relocation of tibialis posterior tendon insertion in the treatment of symptomatic accessory navicular and its relation to the pes planus was studied in 28 patients with symptomatic accessory navicular. Two hundred non-affected individuals were used as control. The calcaneal pitch angle measured radiographically, was used as an indicator of pes planus. All patients had had an excision of the accessory navicular and relocation of the tibialis posterior tendon insertion (Kidner procedure). The average follow-up was 3.2 years. The results were good in 27 patients, and fair in 1 patient

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Robinson, Tyler P., Daniel P. Milgrom, Santosh Nagaraju, William C. Goggins, Kannan P. Samy, and Leonidas G. Koniaris. "Bilateral Renal Auto-Transplantation for Retroperitoneal Sarcomas: Is It Underutilized?" Current Oncology 30, no. 8 (2023): 7620–26. http://dx.doi.org/10.3390/curroncol30080552.

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Sarcomas are a rare tumor of mesenchymal origin. The liposarcoma is the most common sarcoma of the retroperitoneum. Liposarcomas are typically low grade, and present at an advanced stage and a large size. We report a case of a large retroperitoneal liposarcoma, approximately 50 kg, encasing both kidneys, which was managed via a two-stage resection and staged renal auto-transplantation into the intra-peritoneal pelvis. The patient maintained normal renal function throughout, and remains disease free two years post-resection. Renal auto-transplantation with pelvic placement may facilitate improv

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Barisione, Chiara, Daniela Verzola, Silvano Garibaldi, et al. "Renal Ischemia/Reperfusion Early Induces Myostatin and PCSK9 Expression in Rat Kidneys and HK-2 Cells." International Journal of Molecular Sciences 22, no. 18 (2021): 9884. http://dx.doi.org/10.3390/ijms22189884.

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During visceral interventions, the transient clampage of supraceliac aorta causes ischemia/reperfusion (I/R) in kidneys, sometime resulting in acute renal failure; preclinical studies identified redox imbalance as the main driver of I/R injury. However, in humans, the metabolic/inflammatory responses seem to prevail on oxidative stress. We investigated myostatin (Mstn) and proprotein convertase subtilisin/kexin type 9 (PCSK9), proatherogenic mediators, during renal I/R. Compared to sham-operated animals, the kidneys of rats who had experienced ischemia (30 min) had higher Mstn and PCSK9 expres

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Uslu, Mehmet, Mehmet Ezer, Umit Yildirim, Murat Bagcioglu, and Kemal Sarica. "A Novel Technique for Relocating Renal Lower Calyceal Stones During Retrograde Intrarenal Surgery: ‘’Jab and Pull’’." New Journal of Urology 19, no. 1 (2024): 1–7. http://dx.doi.org/10.33719/nju1339275.

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Objective : It is advised to move the stones from the lower calyx to the middle or upper calyx using a nitinol basket. In order to protect the flexible ureterorenoscopy and increase the stone-free rate during retrograde intrarenal surgery In this descriptive study, we presented a method for moving stones to other calyces where the need for deflection is less, using holmium fiber in cases where the nitinol basket is not available. Materials and Methods: With the “Jab and Pull” method we have described, 32 patients who underwent RIRS for symptomatic (pain or infection) renal lower calyceal stone

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Kravchenko, Julia, Masudul Hoque, and Igor Akushevich. "CHRONIC CONDITIONS DURING THE COVID PANDEMIC: MORTALITY PATTERNS IN THE UNITED STATES." Innovation in Aging 6, Supplement_1 (2022): 257. http://dx.doi.org/10.1093/geroni/igac059.1021.

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Abstract Patients with chronic diseases, especially the older adults, are at increased risk of death during the COVID pandemic. We analyzed monthly patterns of mortality rates for patients with diabetes, arterial hypertension, cerebrovascular disease, heart failure, and kidney disease using the provisional Multiple Cause of Death data (2018-2022), for age-, gender, and race/ethnicity-specific population groups. Since population is available at annual basis, we used interpolation of population at risk to have the estimates of population at monthly basis. For all studied diseases, there were sub

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OLESTI RAYO, ANDREU. "La solidaridad en la gestión de los flujos migratorios internos de la Unión Europea." RVAP 128-II, no. 128-II (April 1, 2024): 23–57. http://dx.doi.org/10.47623/ivap-rvap.128.2024.2.01.

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La designada crisis de los refugiados obligó a replantearse la política de gestión de la política migratoria y la política de asilo, pues las consecuencias del traslado de cientos de miles de personas en el espacio Schengen ponía en peligro la efectiva libre circulación de personas. Entre las medidas propuestas destacan las relativas a la creación de un mecanismo de reubicación entre los Estados miembros, de las personas solicitantes de protección internacional. Los inconvenientes e impedimentos para alcanzar un sistema estable, previsible y solidario

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Borwick, Kimberly, Christine Loignon, Chantal Viscogliosi, Bibiane Courtois, Marie-Claude Battista, and Frédérick D’Aragon. "Culturally Safe Care Barriers and Facilitators in Organ Transplantation and Donation According to First Nations and Health Professionals in Quebec, Canada." Progress in Transplantation, August 14, 2024. http://dx.doi.org/10.1177/15269248241268672.

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Introduction: First Nations are most at risk of developing end-stage kidney disease. Kidney transplantation is the best treatment option for these patients; however, First Nations donors are underrepresented. The aim of this study was to describe and understand barriers and facilitators of culturally safe organ transplantation and donation from the perspective of First Nations and Health Professionals in the Province of Quebec, Canada. Methods/Approach: This was a qualitative descriptive study using the decolonizing Two-Eyed Seeing approach. The sample consisted of First Nations people and hea

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Yang, Jenq-Lin. "Maintaining Cerebral-Endothelial Integrity and Permeability Guard Against Uremic Toxins Induced Cognitive Impairment." Physiology 38, S1 (2023). http://dx.doi.org/10.1152/physiol.2023.38.s1.5728887.

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Chronic kidney disease (CKD) is with a characterization of progressing loss of renal function; commonly, CKD progression leads to multiple comorbidities, including neurological dysfunction and immune disorders. Our previous study reported that accumulation of uremic toxins, including creatinine, blood urea nitrogen (BUN), indoxyl sulfate (IS), and p-cresol sulfate (PCS), could not only induce neuronal inflammation, but also NLRP3-inflammasome-correlated astrocytic inflammation; both neuronal and astrocytic inflammation significantly contribute to CKD-triggered cognitive impairment. Our study a

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Jabbarli, I. Sh, D. D. Ivanov, I. V. Krasiuk, L. D. Denova, I. M. Zavalna та Ye K. Lagodych. "Organization of nephrological care for patients with terminal chronic kidney disease and concomitant SARS-CоV-2 infection under martial law: a retrospective study (2022–2024)". KIDNEYS 14, № 2 (2025). https://doi.org/10.22141/2307-1257.14.2.2025.525.

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Background. Patients with chronic kidney disease (CKD) are one of the most vulnerable populations during pandemics due to impaired immune response, frequent hospitalizations, and dependence on life-sustaining renal replacement therapy. SARS-CoV-2 may directly affect renal structures via ACE2 receptors expressed in proximal tubules and indirectly through systemic inflammation and hypercoagulability. In dialysis patients, COVID-19 is associated with increased risk of complications, erythropoietin resistance, and high mortality. Since the beginning of the armed conflict in Ukraine in 2022, nephr

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Davtyan, K. V., N. A. Mironova, I. A. Chugunov, E. M. Gupalo, and A. G. Topchyan. "Cardiac contractility modulation therapy in patients with implanted cardiac resynchronization therapy: results of the 2 year follow-up." Journal of Arrhythmology, July 12, 2023. http://dx.doi.org/10.35336/va-1145.

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Aim. Cardiac contractility modulation (CCM) is a device therapy for patients with heart failure with reduced ejection fraction (HFrEF), most of the data on its programming are concerned patients with narrow QRS and of limited follow up. Our aim was to propose programming approach for Optimizer device in setting of wide QRS complex and fragmented ventricular local activation.Methods. We enrolled 11 patients with HFrEF (median age, 8 males, median NYHA class 3) and LBBB-related wide QRS complex, who underwent Optimizer™ device implantation. Three patients got Optimizer™ IV system and eight patie

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Sayer, Michael, Christian Thiel, Martin Schenk, et al. "Intraperitoneal extension of the peritoneal dialysis catheter—a new technique for catheter implantation in patients with obesity." Journal of Nephrology, July 8, 2021. http://dx.doi.org/10.1007/s40620-021-01077-z.

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Abstract Background In patients with obesity and end-stage kidney disease, implantation of the peritoneal dialysis (PD) catheter may be complicated by increased abdominal circumference or skin folds. Relocation of the implantation site to the upper abdomen could solve this problem. However, this would require an extended catheter. Methods We developed an extended PD catheter based on a swan neck Missouri PD catheter with the help of two adaptors and a straight intraperitoneal extension segment. The extended catheter was assembled intraoperatively, and its length was adjusted individually to en

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Gorham, Gillian, Kirsten Howard, Joan Cunningham, et al. "Dialysis attendance patterns and health care utilisation of Aboriginal patients attending dialysis services in urban, rural and remote locations." BMC Health Services Research 22, no. 1 (2022). http://dx.doi.org/10.1186/s12913-022-07628-9.

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Abstract Background Aboriginal people in the Northern Territory (NT) suffer the heaviest burden of kidney failure in Australia with most living in remote areas at time of dialysis commencement. As there are few dialysis services in remote areas, many Aboriginal people are required to relocate often permanently, to access treatment. Missing dialysis treatments is not uncommon amongst Aboriginal patients but the relationship between location of dialysis service and dialysis attendance (and subsequent hospital use) has not been explored to date. Aim To examine the relationships between location o

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Huang, Bo, Junwu Ren, Qiang Ma, et al. "A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway." Molecular Cancer 23, no. 1 (2024). http://dx.doi.org/10.1186/s12943-024-01940-0.

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Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most prevalent kidney cancer with high aggressive phenotype and poor prognosis. Accumulating evidence suggests that circRNAs have been identified as pivotal mediators in cancers. However, the role of circRNAs in ccRCC progression remains elusive. Methods The differentially expressed circRNAs in 4 paired human ccRCC and adjacent noncancerous tissues ccRCC were screened using circRNA microarrays and the candidate target was selected based on circRNA expression level using weighted gene correlation network analysis (WGCNA) and the

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Gorham, Gillian, Kirsten Howard, Joan Cunningham, Federica Barzi, Paul Lawton, and Alan Cass. "Do remote dialysis services really cost more? An economic analysis of hospital and dialysis modality costs associated with dialysis services in urban, rural and remote settings." BMC Health Services Research 21, no. 1 (2021). http://dx.doi.org/10.1186/s12913-021-06612-z.

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Abstract Background Rates of end-stage kidney disease in Australia are highest in the Northern Territory (NT), with the burden of disease heaviest in remote areas. However, the high cost of delivering dialysis services in remote areas has resulted in centralisation, requiring many people to relocate for treatment. Patients argue that treatment closer to home improves health outcomes and reduces downstream healthcare use. Existing dialysis cost studies have not compared total health care costs associated with treatment in different locations. Objective To estimate and compare, from a payer pers

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Ozmen, Ozlem, Hale Secilmis, Leyla Elif Ozgu Ayozger, and M. Cagri Karakurum. "Clinical and pathological insights into severe acute copper poisoning with extreme liver and kidney accumulation." Veterinary Record Case Reports, April 4, 2025. https://doi.org/10.1002/vrc2.70062.

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AbstractThis study investigated acute copper poisoning in sheep, resulting in 42 deaths out of 170 (24.7%) within 1 week. The owner had an orchard near the pasture that was sprayed with copper sulphate for pest control 2 months earlier. Although the sheep were usually kept away from this area, the gates were opened during rain for shelter, allowing some to enter, drink rainwater, and eat fallen leaves and grass. Two weeks later, clinical signs emerged, including tachycardia, dyspnoea, jaundice and anorexia. Despite relocating the sheep to another pasture, fatalities continued. Two sheep were b

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Bouzid, Fériel, Fabienne Brégeon, Hubert Lepidi, Helen D. Donoghue, David E. Minnikin, and Michel Drancourt. "Ready Experimental Translocation of Mycobacterium canettii Yields Pulmonary Tuberculosis." Infection and Immunity 85, no. 12 (2017). http://dx.doi.org/10.1128/iai.00507-17.

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ABSTRACT Mycobacterium canettii, which has a smooth colony morphology, is the tuberculous organism retaining the most genetic traits from the putative last common ancestor of the rough-morphology Mycobacterium tuberculosis complex. To explore whether M. canettii can infect individuals by the oral route, mice were fed phosphate-buffered saline or 106 M. canettii mycobacteria and sacrificed over a 28-day experiment. While no M. canettii was detected in negative controls, M. canettii-infected mice yielded granuloma-like lesions for 4/4 lungs at days 14 and 28 postinoculation (p.i.) and positive P

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Alkhatib, Ismail, Sami Alasfar, Gilbert Burnham, and Nimetcan Mehmet Orhun. "End-stage kidney diseases in areas of conflict: patients’ perspective and patient access to hemodialysis services in Northwest Syria." BMC Health Services Research 25, no. 1 (2025). https://doi.org/10.1186/s12913-025-12673-1.

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Abstract Background There are an estimated 850 persons with End-Stage Kidney Disease (ESKD) receiving hemodialysis in the conflict-affected Northwest Syria. This study examines patients’ perspectives, and experiences with hemodialysis and their knowledge about their disease and treatment. Methods This study used telephone interviews with 101 randomly selected ESKD patients from 12 of the 14 hemodialysis units in Northwest Syria during early 2023 in a cross-sectional study. Results The mean age of respondents was 50.3 ± 16.7 years (range 7 to 81), with 55.4% males. The sample included 53 local

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