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Thematische Bibliographien / Marv

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Auswahl der wissenschaftlichen Literatur zum Thema „Marv“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 18. Februar 2022

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Zeitschriftenartikel zum Thema "Marv"

1

Blair, Paul, Maryam Keshtkar-Jahromi, Kevin Psoter, Ronald Reisler, Travis Warren, Sara Johnston, Arthur Goff, Lydia Downey, Sina Bavari und Anthony Cardile. „Virulence of Marburg Virus Angola Compared to Mt. Elgon (Musoke) in Macaques: A Pooled Survival Analysis“. Viruses 10, Nr. 11 (21.11.2018): 658. http://dx.doi.org/10.3390/v10110658.

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Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a dearth of published evidence supporting the higher virulence of MARV/Ang. In this retrospective study, we used data pooled from eight separate studies in nonhuman primates experimentally exposed with either 1000 pfu intramuscular (IM) MARV/Ang or MARV/MtE-Mus between 2012 and 2017 at the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). Multivariable Cox proportional hazards regression was used to evaluate the association of variant type with time to death, the development of anorexia, rash, viremia, and 10 select clinical laboratory values. A total of 47 cynomolgus monkeys were included, of which 18 were exposed to MARV/Ang in three separate studies and 29 to MARV/MtE-Mus in five studies. Following universally fatal Marburg virus exposure, compared to MARV/MtE-Mus, MARV/Ang was associated with an increased risk of death (HR = 22.10; 95% CI: 7.08, 68.93), rash (HR = 5.87; 95% CI: 2.76, 12.51) and loss of appetite (HR = 35.10; 95% CI: 7.60, 162.18). Our data demonstrate an increased virulence of MARV/Ang compared to MARV/MtE-Mus variant in the 1000 pfu IM cynomolgus macaque model.

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Bozhanova, Nina G., Amandeep K. Sangha, Alexander M. Sevy, Pavlo Gilchuk, Kai Huang, Rachel S. Nargi, Joseph X. Reidy et al. „Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions“. Proceedings of the National Academy of Sciences 117, Nr. 49 (23.11.2020): 31142–48. http://dx.doi.org/10.1073/pnas.1922654117.

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Marburg virus (MARV) disease is lethal, with fatality rates up to 90%. Neutralizing antibodies (Abs) are promising drug candidates to prevent or treat the disease. Current efforts are focused in part on vaccine development to induce such MARV-neutralizing Abs. We analyzed the antibody repertoire from healthy unexposed and previously MARV-infected individuals to assess if naïve repertoires contain suitable precursor antibodies that could become neutralizing with a limited set of somatic mutations. We computationally searched the human Ab variable gene repertoire for predicted structural homologs of the neutralizing Ab MR78 that is specific to the receptor binding site (RBS) of MARV glycoprotein (GP). Eight Ab heavy-chain complementarity determining region 3 (HCDR3) loops from MARV-naïve individuals and one from a previously MARV-infected individual were selected for testing as HCDR3 loop chimeras on the MR78 Ab framework. Three of these chimerized antibodies bound to MARV GP. We then tested a full-length native Ab heavy chain encoding the same 17-residue-long HCDR3 loop that bound to the MARV GP the best among the chimeric Abs tested. Despite only 57% amino acid sequence identity, the Ab from a MARV-naïve donor recognized MARV GP and possessed neutralizing activity against the virus. Crystallization of both chimeric and full-length native heavy chain-containing Abs provided structural insights into the mechanism of binding for these types of Abs. Our work suggests that the MARV GP RBS is a promising candidate for epitope-focused vaccine design to induce neutralizing Abs against MARV.

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Enterlein, Sven, Viktor Volchkov, Michael Weik, Larissa Kolesnikova, Valentina Volchkova, Hans-Dieter Klenk und Elke Mühlberger. „Rescue of Recombinant Marburg Virus from cDNA Is Dependent on Nucleocapsid Protein VP30“. Journal of Virology 80, Nr. 2 (15.01.2006): 1038–43. http://dx.doi.org/10.1128/jvi.80.2.1038-1043.2006.

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ABSTRACT Here we report recovery of infectious Marburg virus (MARV) from a full-length cDNA clone. Compared to the wild-type virus, recombinant MARV showed no difference in terms of morphology of virus particles, intracellular distribution in infected cells, and growth kinetics. The nucleocapsid protein VP30 of MARV and Ebola virus (EBOV) contains a Zn-binding motif which is important for the function of VP30 as a transcriptional activator in EBOV, whereas its role for MARV is unclear. It has been reported previously that MARV VP30 is able to support transcription in an EBOV-specific minigenome system. When the Zn-binding motif was destroyed, MARV VP30 was shown to be inactive in the EBOV system. While it was not possible to rescue recombinant MARV when the VP30 plasmid was omitted from transfection, MARV VP30 with a destroyed Zn-binding motif and EBOV VP30 were able to mediate virus recovery. In contrast, rescue of recombinant EBOV was not supported by EBOV VP30 containing a mutated Zn-binding domain.

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Daddario-DiCaprio, Kathleen M., Thomas W. Geisbert, Joan B. Geisbert, Ute Ströher, Lisa E. Hensley, Allen Grolla, Elizabeth A. Fritz, Friederike Feldmann, Heinz Feldmann und Steven M. Jones. „Cross-Protection against Marburg Virus Strains by Using a Live, Attenuated Recombinant Vaccine“. Journal of Virology 80, Nr. 19 (01.10.2006): 9659–66. http://dx.doi.org/10.1128/jvi.00959-06.

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ABSTRACT Marburg virus (MARV) has been associated with sporadic episodes of hemorrhagic fever, including a recent highly publicized outbreak in Angola that produced severe disease and significant mortality in infected patients. MARV is also considered to have potential as a biological weapon. Recently, we reported the development of a promising attenuated, replication-competent vaccine against MARV based on recombinant vesicular stomatitis virus (VSV) expressing the glycoprotein of the Musoke strain of MARV (VSVΔG/MARVGP-Musoke). We used this vaccine to demonstrate complete protection of cynomolgus monkeys against a homologous MARV challenge. While these results are highly encouraging, an effective vaccine would need to confer protection against all relevant strains of MARV. Here, we evaluated the protective efficacy of the VSVΔG/MARVGP-Musoke vaccine against two heterologous MARV strains, the seemingly more pathogenic Angola strain and the more distantly related Ravn strain. In this study, seven cynomolgus monkeys were vaccinated with the VSVΔG/MARVGP-Musoke vector. Three of these animals were challenged with the Angola strain, three with the Ravn strain, and a single animal with the Musoke strain of MARV. Two animals served as controls and were each injected with a nonspecific VSV vector; these controls were challenged with the Angola and Ravn strains, respectively. Both controls succumbed to challenge by day 8. However, none of the specifically vaccinated animals showed any evidence of illness either from the vaccination or from the MARV challenges and all of these animals survived. These data suggest that the VSVΔG/MARVGP-Musoke vaccine should be sufficient to protect against all known MARV strains.

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Warfield, Kelly L., Steven B. Bradfute, Jay Wells, Loreen Lofts, Meagan T. Cooper, D. Anthony Alves, Daniel K. Reed, Sean A. VanTongeren, Christine A. Mech und Sina Bavari. „Development and Characterization of a Mouse Model for Marburg Hemorrhagic Fever“. Journal of Virology 83, Nr. 13 (15.04.2009): 6404–15. http://dx.doi.org/10.1128/jvi.00126-09.

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ABSTRACT The lack of a mouse model has hampered an understanding of the pathogenesis and immunity of Marburg hemorrhagic fever (MHF), the disease caused by marburgvirus (MARV), and has created a bottleneck in the development of antiviral therapeutics. Primary isolates of the filoviruses, i.e., ebolavirus (EBOV) and MARV, are not lethal to immunocompetent adult mice. Previously, pathological, virologic, and immunologic evaluation of a mouse-adapted EBOV, developed by sequential passages in suckling mice, identified many similarities between this model and EBOV infections in nonhuman primates. We recently demonstrated that serially passaging virus recovered from the liver homogenates of MARV-infected immunodeficient (SCID) mice was highly successful in reducing the time to death in these mice from 50 to 70 days to 7 to 10 days after challenge with the isolate MARV-Ci67, -Musoke, or -Ravn. In this study, we extended our findings to show that further sequential passages of MARV-Ravn in immunocompetent mice caused the MARV to kill BALB/c mice. Serial sampling studies to characterize the pathology of mouse-adapted MARV-Ravn revealed that this model is similar to the guinea pig and nonhuman primate MHF models. Infection of BALB/c mice with mouse-adapted MARV-Ravn caused uncontrolled viremia and high viral titers in the liver, spleen, lymph node, and other organs; profound lymphopenia; destruction of lymphocytes within the spleen and lymph nodes; and marked liver damage and thrombocytopenia. Sequencing the mouse-adapted MARV-Ravn strain revealed differences in 16 predicted amino acids from the progenitor virus, although the exact changes required for adaptation are unclear at this time. This mouse-adapted MARV strain can now be used to develop and evaluate novel vaccines and therapeutics and may also help to provide a better understanding of the virulence factors associated with MARV.

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Fowler, Trent, Sandra Bamberg, Peggy Möller, Hans-Dieter Klenk, Thomas F. Meyer, Stephan Becker und Thomas Rudel. „Inhibition of Marburg virus protein expression and viral release by RNA interference“. Journal of General Virology 86, Nr. 4 (01.04.2005): 1181–88. http://dx.doi.org/10.1099/vir.0.80622-0.

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High mortality rates and lack of an available vaccine against Marburg haemorrhagic fever (MHF) highlight the need for a defensive therapy against MHF and greater knowledge of the causative agent, the Marburg virus (MARV). Here, RNA interference (RNAi) is employed to destroy MARV transcripts, disrupting replication and allowing analysis of various roles of MARV proteins. Small interfering RNAs (siRNAs) homologous to three MARV transcripts (NP, VP35 and VP30) were co-transfected into cells with plasmids encoding the corresponding nucleocapsid proteins. The resulting decrease in MARV nucleocapsid-protein levels was shown to be specific, as siRNA that was not homologous to the MARV genome did not decrease the levels of viral nucleocapsid proteins. Additionally, transcript levels of double-stranded RNA (dsRNA)-sensor proteins, the dsRNA-activated protein kinase and 2′,5′-oligoadenylate synthetase 1 remained unchanged, suggesting that the decrease in viral proteins was not a result of activation of the antiviral properties of the interferon system. Subsequently, siRNAs were shown to reduce intracellular viral proteins in MARV-infected cells and viral material released into the medium. Targeted reduction of VP30 downregulated the intracellular levels of all other viral proteins, suggesting that VP30 plays an essential role for transcription/replication. The efficient reduction of MARV replication also suggests that RNAi may provide an agent against MHF.

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Polezhaeva, O. A., A. V. Zybkina, A. V. Zaikovskaya, O. V. P’yankov, S. A. P’yankov, A. V. Semenova, G. V. Semenova und D. N. Shcherbakov. „Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus“. Problems of Particularly Dangerous Infections, Nr. 4 (07.02.2021): 86–91. http://dx.doi.org/10.21055/0370-1069-2020-4-86-91.

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The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and pseudovirus particles exhibiting GP of three strains of MARV – Popp, Musoke and DRC2000 based on lentivirus and recombinant strain of vesicular stomatitis virus (VSV) were used as immunogens. Two groups of birds were involved in the study. Chickens were immunized 9 times: first time they were injected with the recombinant vaccinia virus, and then 8 times – with pseudovirus particles (based on lentivirus and a recombinant strain of the vesicular stomatitis virus). The accumulation of specific antibodies was evaluated by enzyme-linked immunosorbent assay (ELISA). We used recombinant VSV exhibiting GP MARV, and natural MARV strain Popp for the analysis of accumulation of neutralizing antibodies.Results and discussion. We have developed an effective immunization schedule for chickens with three recombinant constructs presenting GP MARV, which results in the induction of chicken IgY antibodies against Marburg virus with a titer in ELISA from 1:100 to 1:1 million. The obtained IgY neutralize MARV pseudoviruses (Popp, DRC2000, Musoke) at a dilution of 1/256 to 1/1024 and the natural MARV virus of the Popp strain at a dilution of 1/8. More stable results were demonstrated by immunization using Freund’s incomplete adjuvant.

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Arnold, Catherine, Jonathan Guito, Louis Altamura, Sean Lovett, Elyse Nagle, Gustavo Palacios, Mariano Sanchez-Lockhart und Jonathan Towner. „Transcriptomics Reveal Antiviral Gene Induction in the Egyptian Rousette Bat Is Antagonized In Vitro by Marburg Virus Infection“. Viruses 10, Nr. 11 (02.11.2018): 607. http://dx.doi.org/10.3390/v10110607.

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The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host. ERBs develop a productive MARV infection with low viremia and shedding but no overt disease, suggesting this virus is efficiently controlled by ERB antiviral responses. This dynamic would contrast with humans, where MARV-mediated interferon (IFN) antagonism early in infection is thought to contribute to the severe, often fatal disease. The newly-annotated ERB genome and transcriptome have now enabled us to use a custom-designed NanoString nCounter ERB CodeSet in conjunction with RNA-seq to investigate responses in a MARV-infected ERB cell line. Both transcriptomic platforms correlated well and showed that MARV inhibited the antiviral program in ERB cells, while an IFN antagonism-impaired MARV was less efficient at suppressing the response gene induction, phenotypes previously reported for primate cells. Interestingly, and despite the expansion of IFN loci in the ERB genome, neither MARV showed specific induction of almost any IFN gene. However, we detected an upregulation of putative, unannotated ERB antiviral paralogs, as well as an elevated basal expression in uninfected ERB cells of key antiviral genes.

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Hamilton Spence, Erin, Monica Huff, Karen Shattuck, Amy Vickers, Nadezda Yun und Slobodan Paessler. „Ebola Virus and Marburg Virus in Human Milk Are Inactivated by Holder Pasteurization“. Journal of Human Lactation 33, Nr. 2 (30.01.2017): 351–54. http://dx.doi.org/10.1177/0890334416685564.

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Background: Potential donors of human milk are screened for Ebola virus (EBOV) using standard questions, but testing for EBOV and Marburg virus (MARV) is not part of routine serological testing performed by milk banks. Research aim: This study tested the hypothesis that EBOV would be inactivated in donor human milk (DHM) by standard pasteurization techniques (Holder) used in all North American nonprofit milk banks. Methods: Milk samples were obtained from a nonprofit milk bank. They were inoculated with EBOV (Zaire strain) and MARV (Angola strain) and processed by standard Holder pasteurization technique. Plaque assays for EBOV and MARV were performed to detect the presence of virus after pasteurization. Results: Neither EBOV nor MARV was detectable by viral plaque assay in DHM or culture media samples, which were pasteurized by the Holder process. Conclusion: EBOV and MARV are safely inactivated in human milk by standard Holder pasteurization technique. Screening for EBOV or MARV beyond questionnaire and self-deferral is not needed to ensure safety of DHM for high-risk infants.

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Saito, Takeshi, Junki Maruyama, Noriyo Nagata, Mao Isono, Kosuke Okuya, Yoshihiro Takadate, Yurie Kida et al. „A Surrogate Animal Model for Screening of Ebola and Marburg Glycoprotein-Targeting Drugs Using Pseudotyped Vesicular Stomatitis Viruses“. Viruses 12, Nr. 9 (22.08.2020): 923. http://dx.doi.org/10.3390/v12090923.

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Filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV), cause severe hemorrhagic fever in humans and nonhuman primates with high mortality rates. There is no approved therapy against these deadly viruses. Antiviral drug development has been hampered by the requirement of a biosafety level (BSL)-4 facility to handle infectious EBOV and MARV because of their high pathogenicity to humans. In this study, we aimed to establish a surrogate animal model that can be used for anti-EBOV and -MARV drug screening under BSL-2 conditions by focusing on the replication-competent recombinant vesicular stomatitis virus (rVSV) pseudotyped with the envelope glycoprotein (GP) of EBOV (rVSV/EBOV) and MARV (rVSV/MARV), which has been investigated as vaccine candidates and thus widely used in BSL-2 laboratories. We first inoculated mice, rats, and hamsters intraperitoneally with rVSV/EBOV and found that only hamsters showed disease signs and succumbed within 4 days post-infection. Infection with rVSV/MARV also caused lethal infection in hamsters. Both rVSV/EBOV and rVSV/MARV were detected at high titers in multiple organs including the liver, spleen, kidney, and lungs of infected hamsters, indicating acute and systemic infection resulting in fatal outcomes. Therapeutic effects of passive immunization with an anti-EBOV neutralizing antibody were specifically observed in rVSV/EBOV-infected hamsters. Thus, this animal model is expected to be a useful tool to facilitate in vivo screening of anti-filovirus drugs targeting the GP molecule.

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Dissertationen zum Thema "Marv"

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Murdough, Adam C. „Worlds Will Live, Worlds Will Die: Myth, Metatext, Continuity and Cataclysm in DC Comics’ Crisis on Infinite Earths“. Connect to this title online, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1151329477.

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Bode, Matthias [Verfasser], Steffen [Akademischer Betreuer] Marx und Peter [Akademischer Betreuer] Mark. „Energetische Schädigungsanalyse von ermüdungsbeanspruchtem Beton / Matthias Bode ; Steffen Marx, Peter Mark“. Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2020. http://d-nb.info/1224045866/34.

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Selamé, Glena Nicole. „Mare nostrum : el derecho de salida al mar de los pueblos“. Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/279395.

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Esta tesis defiende un derecho universal de salida al mar. La falta de acceso marítimo priva a los Estados de la autonomía necesaria para perseguir sus fines y menoscaba sus posibilidades de desarrollo. Sostengo que a pesar de que Rawls es un improbable aliado de este proyecto, este derecho puede ser defendido desde una perspectiva rawlsiana. Rechazo la objeción de que los Estados acosteros puedan considerarse colectivamente responsables por su situación y que sea necesario hacer responsables a los otros Estados para exigir una solución. Apelo a teorías cercanas a la tradición geoísta que sostienen que el planeta pertenece a toda la humanidad y que la distribución desigual de los recursos debe ser compensada, y respondo a una posible objeción. Finalmente, rechazo la idea de que mi propuesta pueda ser rebatida sobre la base de la idea de soberanía y derechos territoriales.
This thesis defends a universal right to access the sea. The lack of access deprives states of the autonomy they need to pursue their goals and undermines their development potential. I hold that though John Rawls is an unlikely allied to this project, this right can be defended from a Rawlsian perspective. I reject the objection that landlocked states can be considered collectively responsible for their situation and I also deny it is necessary to hold other states collectively responsible in order to demand a solution. I appeal to theories close to the geoist tradition that claim the planet belongs to all humanity and that a very unequal distribution of resources should be redressed. I also reply to a possible geoist objection to my proposal. Finally, I object to the idea that a conclusive argument against my proposal can be grounded on the ideas of sovereignty and territorial rights.

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Sanio, David [Verfasser], Peter [Gutachter] Mark und Steffen [Gutachter] Marx. „Genauigkeit monitoringbasierter Lebensdauerprognosen von Betonbrücken bei Spannstahlermüdung / David Sanio ; Gutachter: Peter Mark, Steffen Marx“. Bochum : Ruhr-Universität Bochum, 2017. http://d-nb.info/1127335146/34.

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Romano, Ana Lucia Travassos. „Analise espectral e modelagem adaptativa de sinais de mare em mar semi-fechado“. [s.n.], 1995. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261952.

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Orientador: Amauri Lopes
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica
Made available in DSpace on 2018-07-20T02:59:35Z (GMT). No. of bitstreams: 1 Romano_AnaLuciaTravassos_M.pdf: 7197475 bytes, checksum: 0c76fbaba88c387b05ddae90f765dfe6 (MD5) Previous issue date: 1995
Resumo: O objetivo deste trabalho é estudar o comportamento das flutuações de maré em mar semi-fechado, através de técnicas de processamento de sinais e de análise espectral. Com isso pretende-se estabelecer um comportamento padrão para a região em estudo (Baía de Sepetiba) e, sobretudo, mostrar o potencial de aplicação das ferramentas desenvolvidas para a análise. Os métodos utilizados são: Análise Clássica de Fourier, onde através de algoritmos de Transformada Rápida (FFT) obtém-se a densidade espectral de freqüência pelo método do Periodograma; Métodos Paramétricos, visando uma maior definição do espectro e estabelecendo um modelo auto-regressivo para o sinal, a partir dos dados disponíveis; Métodos Adaptativos, finalmente levando-se em conta o caráter não estacionário do sinal de maré e obtendo-se um modelo auto-regressivo de forma adaptativa, o qual permite acompanhar as variações de freqüência e, principalmente, de intensidade das diversos componentes de maré ao longo do ano. Os resultados apresentados mostram que os espectros obtidos por FFI, por Modelamento AR e por Filtragem Adaptativa, estiveram de acordo entre si e com os obtidos teoricamente. Os três métodos podem ser utilizados em qualquer conjunto de dados de altura do nível do mar e podem referir-se a qualquer âmbito de intervalo de freqüência de maré. O modelo AR, adaptativo ou não, abre novas e interessantes perspectivas para a análise da curva de maré, conseguindo bom desempenho, mesmo com número limitado de dados, e viabilizando previsões com base nesses modelos
Abstract: Not informed.
Mestrado
Mestre em Engenharia Elétrica

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Kotrba, Karen J. „She Who is Like a Mare: Poems of Mary Breckinridge and the Frontier Nursing Service“. Youngstown State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1290961163.

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Pesant, Monique. „Développement de l'intrigue dans l'Évangile de Marc : Rhoads et Michie (1982) et Kingsbury (1989) revisités“. Master's thesis, Université Laval, 2002. http://hdl.handle.net/20.500.11794/66133.

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À la suite de Rhoads et Michie (1982), et de Kingsbury (1989), l’évangile de Marc est étudié comme récit. Le développement de l’intrigue est analysé en fonction des divers types de conflits qui surviennent entre Jésus et les forces d’opposition à l’avènement du Règne de Dieu. Le Mémoire comporte trois parties. Première partie: préalables à l'étude — problématique (p. 6-20); précision des termes (p. 21-48). Deuxième partie: aspects méthodologiques — théorie du récit (p. 50-90); procédure d'analyse des données et de présentation des résultats (p. 91-99). Troisième partie: développement de l'intrigue — vue d’ensemble de l’évangile (p. 101-135); conflits entre Jésus et les forces d'opposition à l'avènement du Règne de Dieu (p. 136-365). Le Mémoire comporte 105 tableaux présentés en appendices.

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Costa, Daniel Silva. „Variação do nível médio do mar - técnicas para a avaliação“. Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/3/3138/tde-17012008-110654/.

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A variação do Nível Médio do Mar (NMM) é um assunto de grande importância para a sociedade, pois a sua elevação, que é verificada em diversas estações de monitoramento no mundo, pode trazer diversos prejuízos para o homem. Aponta-se como razão principal deste fenômeno a elevação da temperatura média do planeta causada pelo aumento da concentração dos Gases de Efeito Estufa (GEE). Em Cananéia, litoral sul do estado de São Paulo, o nível do mar vem sendo monitorado há mais de 50 anos através de um marégrafo. A estação também conta, desde o ano de 2002, com um receptor do Global Positioning System (GPS) cuja antena está instalada em um pilar adequado, engastado na rocha. Além disso, um gravímetro geodinâmico foi instalado junto à estação para, associado ao marégrafo e ao receptor GPS, contribuir para a determinação da variação absoluta do NMM, que representa a diferença entre os movimentos do nível do mar e da crosta. Com os dados maregráficos durante o período de 1954 a 2004 foi possível determinar um aumento relativo do NMM de 4,2 mm/ano, com a determinação de um modelo global de marés oceânicas que melhor se adaptou à região. A análise das observações gravimétricas permitiram a determinação de um modelo de maré terrestre para a estação, porém a deriva instrumental impediu a detecção de alguma tendência para a crosta. Já os resultados obtidos através do processamento das observações GPS entre os anos de 2004 e 2006 através do método Precise Point Positioning (PPP) determinaram um rebaixamento da crosta de 1,59 mm/ano. No entanto, este curto período de observações processadas impede que se conclua algo de definitivo sobre o movimento da crosta.
The Mean Sea Level (MSL) variation is very important for the society because its elevation, verified in many monitoring stations around the world, causes several damages for the humanity. It\'s pointed how principal reason of this phenomena the elevation of the world mean temperature due to greenhouse gases concentration increasing. At Cananéia, south coast of São Paulo, the sea level has been monitored for more than 50 years by a tide gauge. The station has since 2002 a GPS receiver whose antenna is installed in a stable pillar fixed in the bed rock. Moreover a geodynamic gravitymeter installed at the site of the station, out of the tide gauge and the GPS receiver, contributes for the determination of absolute variation of the MSL that represents the difference between the movement of the sea level and the crust. With tide gauge observations from 1954 to 2004 it was possible to find a relative increasing of MSL of 4.2 mm/year with the determination of the ocean tide model that best fit in the region. The analysis of gravimetric observations allowed the determination of an earth tide model but the instrumental drift hindered the detection of some crust tendency. However the results obtained by processing GPS observations between 2004 and 2006 by Precise Point Positioning showed a decrease of the crust of 1.59 mm/year. However, any definite conclusion on the crust movement need a longe period of observations with GPS.

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CARNEIRO, Isis Santos Cabral. „Comunidade de peixes nas piscinas de maré do Atol das Rocas, Brasil : a influência da conexão com o mar“. Universidade Federal Rural de Pernambuco, 2016. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5228.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
The reef environments have the highest species diversity among marine ecosystems. The reef fish communities are characterized by their high diversity, both in terms of numbers of species as in morphology and are important components of the biota of these environments, working in the structuring of communities through predation and competition processes. The structure of fish populations respond to various environmental factors (rainfall regime, environmental geomorphology, tidal dynamics, water transparency, quality and type of organic matter, current velocity and availability of food resources), these factors influence the spatial distribution and temporal species. Thus, this aimed to understand the timeline distribution of fish populations between the pools with or without connection to the open sea in Rocas Atoll, identifying the environmental characteristics with the greatest influence on the structure of fish populations. This is the only atoll in the South Atlantic Ocean and is located 266 km off the Brazilian coast, differs from other atolls because it is composed exclusively of algae encrusting coralline. In its plateau occur tidal pools, canals and sandy islands. 90 hours of diving were held in two pools with connection to the open sea and two disjoint through five linearly arranged transects the edge to the center of the pool, including the dry and rainy seasons. The temperature data were recorded, salinity, pH and dissolved oxygen from each pool much water in the dry season and the rainy. It was identified to the substrate composition of the pools through the photos using the methodology Coral Point Count with Excel Extensions program. 12,065 individuals, distributed in 20 families and 33 species were observed. The pools with connection with the sea showed the highest values of diversity and abundance and presented as the most abundant species Thalassoma noronhanum, Acanthurus chirurgus, Abudefduf saxatilis and Stegastes rocacensis, these species are equivalent to 87.3% of relative abundance these pools. The pools without connection with the sea showed a difference in the fish community in comparison to the pools with connection, being the most abundant species the A.saxatilis, A. chirurgus, T. noronhanum and Haemulon chrysargyreum. The richness, diversity and equitability varied between climatic periods and connection type. A significant correlation between the diversity and depth (RS 0,322e = p <0.05) was observed. They were observed seven types of substrate: coral, zoanthid, turf algae, seaweed, corallinae algae, gravel and sand. The substrate showed a correlation between the two pools open with rS = 0.857, p <0.05 where both presented seaweed as most of the substrate. In Rocas Atoll the connection type and depth of the pool, time of year and the type of substrate influence the composition and distribution of fish populations between the pools.
Os ambientes recifais apresentam a maior diversidade de espécies dentre os ecossistemas marinhos. As comunidades de peixes recifais são caracterizadas pela sua elevada diversidade, tanto em termos de números de espécies como em morfologia, sendo componentes importantes da biota destes ambientes, atuando na estruturação das comunidades através de processos de predação e competição. A estrutura da ictiofauna responde a diversos fatores ambientais (regime de pluviosidade, geomorfologia do ambiente, dinâmica da maré, transparência da água, qualidade e tipo de matéria orgânica, velocidade das correntes e disponibilidade dos recursos alimentares), esses fatores influenciam na distribuição espacial e temporal das espécies. Desta forma, o presente objetivou compreender a distribuição espaço temporal da ictiofauna entre as piscinas com ou sem conexão com o mar aberto no Atol das Rocas, identificando as características ambientais com maior influência na estruturação da ictiofauna. Este é o único atol do Oceano Atlântico Sul e está localizado a 266 km da costa brasileira, difere dos outros atóis porque é composto exclusivamente por algas coralíneas incrustantes. Em seu platô ocorrem piscinas de maré, canais e ilhas arenosas. Foram realizadas 90 horas de mergulho, em duas piscinas com conexão com o mar aberto e duas sem conexão, por meio de cinco transectos dispostos linearmente da borda para o centro da piscina, abrangendo os períodos seco e chuvoso. Foram registrados os dados de temperatura, salinidade, pH e oxigênio dissolvido da água de cada piscina tanto no período seco como no chuvoso. Foi identificada a composicão do substrato das piscinas através da metodologia de fotografias utilizando o programa Coral Point Count with Excel Extensions. Foram observados 12.065 indivíduos, distribuídos em 20 famílias e 33 espécies. As piscinas com conexão com o mar apresentaram os maiores valores de diversidade e abundância e apresentaram como espécie mais abundantes Thalassoma noronhanum, Acanthurus chirurgus, Abudefduf saxatilise, Stegastes rocacensis, essas espécies equivalem a 87,3% da abundância relativa dessas piscinas. As piscinas sem conexão com o mar apresentaram uma diferença na composição ictiofaunística em comparação com as piscinas fechadas, sendo as espécies mais abundantes o Abudefuf saxatilis, A. chirurgus, T. noronhanum e Haemulonchrysargyreum. Os valores de riqueza, diversidade e equitabilidade variaram entre períodos climáticos e tipo de conexão. Foi observada uma correlação entre a diversidade e profundidade (rS=0,322e p<0,05).Foram observados sete tipos de substrato: coral, zoantídeo, alga turf, macroalga, alga coralínea, cascalho e areia. O substrato apresentou correlação entre as duas piscinas abertas com rS =0,857 e p<0,05 onde ambas apresentaram macroalgas como maior parte do substrato. No Atol das Rocas o tipo de conexão e profundidade da piscina, período do ano e o tipo de substrato influenciam na composição e distribuição da ictiofauna entre as piscinas.

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Massey, Ryan B. „Mari“. Digital Commons at Loyola Marymount University and Loyola Law School, 2016. https://digitalcommons.lmu.edu/etd/281.

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Bücher zum Thema "Marv"

1

Humāyūn, Surūsh, Hrsg. Juljutā dar Marv. [Tehran]: Varashān, 2001.

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Andreyev, Sam. Thoughts of Marv Sandeye. [Toronto]: Expert Press, 2002.

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Balkhābī, Ḥasan Aḥmadī Nizhād Ḥasan. Sīmā-yi Marv: Mīzbān-i khūrshīd. [Tehran]: Sāzmān-i Tablīghāt-i Islāmī, 1997.

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Lee, Stan. Marv el Comics presents The enslavers. New York, N.Y: Marvel Comics, 1990.

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Sīmā-yi Marv: Mīzbān-i khvurshīd. [Tehran]: Sāzmān-i Tablīghāt-i Islāmī, 1997.

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6

Marv, Davidov, Hrsg. You can't do that!: Marv Davidov, nonviolent revolutionary. Minneapolis, MN: Nodin Press, 2009.

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7

Levy, Marv. Marv Levy: Where else would you rather be? New York: Sports Pub., 2011.

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8

Masters, Carol. You can't do that!: Marv Davidov, nonviolent revolutionary. Minneapolis, MN: Nodin Press, 2009.

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Masters, Carol. You can't do that!: Marv Davidov, nonviolent revolutionary. Minneapolis, MN: Nodin Press, 2009.

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Pizhūhishgāh-i ʻUlūm-i Insānī va Muṭālaʻāt-i Farhangī (Tehran, Iran), Hrsg. Masʼalah-ʼi Marv dar tārīkh-i muʻāṣir-i Īrān. Tihrān: Pizhūhishgāh-i ʻUlūm-i Insānī va Muṭālaʻāt-i Farhangī, 2005.

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Buchteile zum Thema "Marv"

1

Mannooramparampil, Thomas. „ACTS OF MAR MARI“. In The Harp (Volume 25), herausgegeben von Baby Varghese, Rev Jacob Thekeparampil und Abraham Kalakudi, 137–54. Piscataway, NJ, USA: Gorgias Press, 2012. http://dx.doi.org/10.31826/9781463233143-012.

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Schenk, Gerrit Jasper. „More Resilient with Mars or Mary?“ In Strategies, Dispositions and Resources of Social Resilience, 139–62. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-29059-7_8.

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Comrie, Bernard. „Markedness“. In Handbook of Pragmatics, 1–13. Amsterdam: John Benjamins Publishing Company, 1997. http://dx.doi.org/10.1075/hop.2.mar2.

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Messina-Dysert, Gina. „Mary“. In Christian Doctrines for Global Gender Justice, 105–17. New York: Palgrave Macmillan US, 2015. http://dx.doi.org/10.1057/9781137462220_7.

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White, James D. „Marx“. In Karl Marx and the Intellectual Origins of Dialectical Materialism, 145–210. London: Palgrave Macmillan UK, 1996. http://dx.doi.org/10.1057/9780230374218_5.

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Fischer, Daniel, und Hilmar Duerbeck. „Mars“. In Hubble Revisited, 177–81. New York, NY: Springer New York, 1998. http://dx.doi.org/10.1007/978-1-4612-2232-3_30.

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Shipman, Harry L. „Mars“. In Humans in Space, 199–223. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4899-6104-4_11.

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Fredrickson, Regina A. „Mary“. In Encyclopedia of Psychology and Religion, 1078–81. Boston, MA: Springer US, 2014. http://dx.doi.org/10.1007/978-1-4614-6086-2_404.

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Henry, Michel. „Marx“. In A Companion to Continental Philosophy, 118–27. Oxford, UK: Blackwell Publishing Ltd, 2017. http://dx.doi.org/10.1002/9781405164542.ch8.

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Löwith, Karl. „Marx“. In Weltgeschichte und Heilsgeschehen, 42–61. Stuttgart: J.B. Metzler, 2004. http://dx.doi.org/10.1007/978-3-476-02944-7_3.

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Konferenzberichte zum Thema "Marv"

1

CHAVY, S., und T. ABENSUR. „Design of penetration-oriented MARV“. In Aerospace Design Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1992. http://dx.doi.org/10.2514/6.1992-1003.

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Moore, Joan, und John Moore. „High Turbulence Turbine Cascade Performance Using the MARV Reynolds Stress Model“. In 47th AIAA Aerospace Sciences Meeting including The New Horizons Forum and Aerospace Exposition. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2009. http://dx.doi.org/10.2514/6.2009-1322.

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Majernik, Filip, Meiko Jensen und Jorg Schwenk. „MARV - Data Level Confidentiality Protection in BPEL-Based Web Service Compositions“. In 2011 Conference on Network and Information Systems Security (SAR-SSI). IEEE, 2011. http://dx.doi.org/10.1109/sar-ssi.2011.5931365.

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Bertolani, Diego Nunes, Vinicius Pacheco Bacheti und Mario Sarcinelli-Filho. „Controlling a formation of a MARV in backward movements with an UAV for inspection tasks**This work was supported by CNPq-Brazil and FAPES-ES, Brazil“. In 2021 International Conference on Unmanned Aircraft Systems (ICUAS). IEEE, 2021. http://dx.doi.org/10.1109/icuas51884.2021.9476748.

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Bean, Quincy, Lisa Tunstill McCollum, Rachel McCauley, Andrew Prince, Darius Yaghoubi und Andrew Schnell. „Mars Ascent Vehicle (MAV) Propulsion Subsystems Design“. In 2019 IEEE Aerospace Conference. IEEE, 2019. http://dx.doi.org/10.1109/aero.2019.8742205.

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Lindemann, Randel. „Dynamic Testing and Simulation of the Mars Exploration Rover“. In ASME 2005 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/detc2005-85622.

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In January of 2004, NASA landed two mobile robotic spacecraft on the surface of Mars as part of the Mars Exploration Rover (MER) project. Named Spirit and Opportunity, each of these rovers is performing their separate scientific missions of exploration more than a year after landing. The Mars Exploration Rovers represent a great advance in planetary rover technology. Part of that advance is represented by the mobility capabilities of these vehicles. At the 1.5 year mark, the two vehicles have traversed more than 10 km over broad plains, craters, rocks, and hills. In order to assess the mobility characteristics of the rovers in the Mars environment, an engineering model vehicle was tested before the mission launches in a representative environment of slopes, rock obstacles, and soft soil. In addition, to gain better insight into the rovers’ capabilities, a dynamic model of the rovers was created in the software package ADAMS. The rover model was then used to simulate many of the test cases, which provided a means for model correction and correlation. The results and lessons learned of the test and dynamic simulation of the MER vehicles is provided in this paper. The results from the test and simulation program allowed Spirit and Opportunity to be used in terrain well outside of the original mission requirements. The resulting increase in terrain access, led to substantial additions to the missions science return.

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Klein, Eric, Erik Nilsen, Austin Nicholas, Charles Whetsel, Joseph Parrish, Richard Mattingly und Lisa May. „The Mobile MAV concept for Mars Sample Return“. In 2014 IEEE Aerospace Conference. IEEE, 2014. http://dx.doi.org/10.1109/aero.2014.6836446.

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De Wagter, Christophe, Bert Bijnens und Jan Albert Mulder. „Vision-Only Control of a Flapping MAV on Mars“. In AIAA Guidance, Navigation and Control Conference and Exhibit. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2007. http://dx.doi.org/10.2514/6.2007-6853.

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Ross, D., J. Russell und B. Sutter. „Mars Ascent Vehicle (MAV): Designing for high heritage and low risk“. In 2012 IEEE Aerospace Conference. IEEE, 2012. http://dx.doi.org/10.1109/aero.2012.6187296.

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Sitina, Natalya, Natalya Sitina, Tatyana Sitina und Tatyana Sitina. „GEOECOLOGICAL CHARACTERISTIC OF THE CHEBOKSARY RESERVOIR COAST“. In Managing risks to coastal regions and communities in a changing world. Academus Publishing, 2017. http://dx.doi.org/10.21610/conferencearticle_58b4316e6a24c.

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Construction of Cheboksary hydroelectric power station with a reservoir was begun in 1968 and was stopped in 1981. The hydrostation was put into operation when filling a reservoir to a mark of 63,0 m with incomplete construction of protective actions. As a result of rise in level of the Cheboksary reservoir to 68,0 m territories of the Nizhny Novgorod Region, the Republics of Mari El and the Chuvash will be flooded. Operation of the Cheboksary reservoir within 33 years on a temporary mark of the retaining level of 63,0 m promotes further development of possible negative impacts and deterioration of life of the population in points of accommodation getting to a zone of influence of a reservoir. In work problems of influence of the Cheboksary reservoir on the nature of adjacent territories are considered. The analysis of influence of natural and technogenic factors on the Cheboksary reservoir is submitted. Comparative research of the territory of a right bank and left bank on studying of hydrological and hydrogeological processes and processing of coast in a zone of influence of a reservoir on key points is conducted. The state is considered recreational development of the territory. Features of a current state of technical objects of the Cheboksary reservoir are defined, the geoecological situation on coast of a reservoir on the studied key sites is revealed. Recommendations about decrease in negative impact of recreational use of coastal zones of a reservoir are developed.

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Berichte der Organisationen zum Thema "Marv"

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Morris, J. MaRV (maneuverable reentry vehicles) PoP (probability of penetration) vs CEP (circular error probability) analysis concept study (MaRV Penetration Study Project). Office of Scientific and Technical Information (OSTI), August 1986. http://dx.doi.org/10.2172/6423110.

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Lozano, G. Mark and Signed Mark Objects Mapping. RFC Editor, Juni 2016. http://dx.doi.org/10.17487/rfc7848.

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Cabrita, Maria Teresa, Ana David und Gonçalo Vieira. Portuguese Polar Program Annual Report 2020. Centro de Estudos Geográficos, Universidade de Lisboa, 2021. http://dx.doi.org/10.33787/ceg20210001.

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The Portuguese Polar Program - PROPOLAR is funded by the Fundação para a Ciência e a Tecnologia ( based at Instituto de Geografia e Ordenamento do Território ( of the University of Lisbon ( The coordination of PROPOLAR is led by the Centro de Estudos Geográficos from Instituto de Geografia e Ordenamento do Território University of Lisbon (CEG/IGOT ULISBOA), under a Coordinating Committee that includes members from 4 other research centres, namely the Centro de Ciências do Mar University of Algarve (CCMAR UALG), the Centro de Ciências do Mar e do Ambiente University of Coimbra (MARE UC), the Centro de Química Estrutural from Instituto Superior Técnico University of Lisboa (CQE/IST ULISBOA), and the Centro Interdisciplinar de Investigação Marinha e Ambiental University of Oporto (CIIMAR U PORTO) Gonçalo Vieira (CEG/IGOT ULISBOA) is the Head of the program The remarkable effort and commitment of the Portuguese Polar scientists, within the framework of the International Polar Year ( 2007 08 were key to promote awareness of the importance of Polar science and research for Portugal A strategic plan encompassing three main objectives was then set out to i creating a Portuguese Polar Program focused on polar research and innovation and supporting the young generation of Polar scientists,scientists,( signing the Antarctic Treaty, and ( implementing a national Polar education and outreach program With the support of the FCT, PROPOLAR started in 2007 Portugal ratified the Antarctic Treaty in 2010 and the Madrid Protocol in 2014 and has established liaisons with major international Polar scientific and management organisations and networks PROPOLAR in close connection with the FCT, has ensured consolidation and sustainability of the development of Portuguese Polar science

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Thomas, Douglas, und Mellon Michael. Sublimation of terrestrial permafrost and the implications for ice-loss processes on Mars. Engineer Research and Development Center (U.S.), Juli 2021. http://dx.doi.org/10.21079/11681/41244.

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Sublimation of ice is rate-controlled by vapor transport away from its outer surface and may have generated landforms on Mars. In ice-cemented ground (permafrost), the lag of soil particles remaining after ice loss decreases subsequent sublimation. Varying soil-ice ratios lead to differential lag development. Here we report 52 years of sublimation measurements from a permafrost tunnel near Fairbanks, Alaska, and constrain models of sublimation, diffusion through porous soil, and lag formation. We derive the first long-term in situ effective diffusion coefficient of ice-free loess, a Mars analog soil, of 9.05 × 10⁻⁶ m² s⁻¹, ~5× larger than past theoretical studies. Exposed ice-wedge sublimation proceeds ~4× faster than predicted from analogy to heat loss by buoyant convection, a theory frequently employed in Mars studies. Our results can be used to map near-surface ice-content differences, identify surface processes controlling landform formation and morphology, and identify target landing sites for human exploration of Mars.

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Deming, M. Elen, und Scott Douglas. Mary Bartelme Park. Landscape Architecture Foundation, 2015. http://dx.doi.org/10.31353/cs0890.

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Buckner, M. R. Mark 22 Reactivity. Office of Scientific and Technical Information (OSTI), Juli 2001. http://dx.doi.org/10.2172/782820.

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Mocko, Michael Jeffrey, Lukas Zavorka und Paul E. Koehler. Lujan Mark-4. Office of Scientific and Technical Information (OSTI), November 2017. http://dx.doi.org/10.2172/1408859.

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AIR FORCE RESEARCH LAB EDWARDS AFB CA. JPL Mars Lander. Fort Belvoir, VA: Defense Technical Information Center, August 2002. http://dx.doi.org/10.21236/ada405516.

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Staelin, D. H., J. W. Barrett, E. J. Kim und H. R. Stuart. Mark III Interferometer. Fort Belvoir, VA: Defense Technical Information Center, September 1989. http://dx.doi.org/10.21236/ada213155.

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Clegg, Samuel M. ChemCam on Mars. Office of Scientific and Technical Information (OSTI), Oktober 2012. http://dx.doi.org/10.2172/1053549.

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