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1

J., V. Pinkerton. "HORMONE THERAPY FOR POSTMENOPAUSAL WOMEN." REPRODUCTIVE ENDOCRINOLOGY, no. 56 (December 30, 2020): 100–106. https://doi.org/10.18370/2309-4117.2020.56.100-106.

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Hormone therapy is recommended for relief from hot flashes or night sweats in women younger than age 60 years or those who entered menopause within 10 years of seeking treatment. Hormone therapy also can reduce bone loss and the risk of fractures; offer a potential cardioprotective benefit; and alleviate the genitourinary symptoms of menopause, including dysfunction of the bladder and irritation of the vagina and vulva. For women with early menopause without contraindications, hormone therapy is recommended until at least the average age of natural menopause. Observational studies suggest that
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Pearce, Jane, Keith Hawton, and Fiona Blake. "Psychological and Sexual Symptoms Associated with the Menopause and the Effects of Hormone Replacement Therapy." British Journal of Psychiatry 167, no. 2 (1995): 163–73. http://dx.doi.org/10.1192/bjp.167.2.163.

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BackgroundThere is considerable inconsistency in the results of studies of the psychological and sexual sequelae of the menopause and their treatment.MethodA search of the literature on Medline was made of studies of psychological symptoms in women who were either naturally or surgically menopausal or who were receiving hormone replacement therapy for menopausal symptoms.ResultsThere is evidence of a small increase in psychological morbidity (not usually amounting to psychiatric disorder) preceding the natural menopause and following the surgical menopause. Psychosocial as well as hormonal fac
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Riya, Fathima V. Christy T. Chacko A. R. Shabaraya. "Menopausal Hormone Therapy And Its Awareness In Women." International Journal in Pharmaceutical Sciences 2, no. 9 (2024): 986–93. https://doi.org/10.5281/zenodo.13820255.

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Menopause results from cease in ovarian follicular function and marks the end of menstruation. Most women experience menopause between the ages of 40 and 58 years. Hormone replacement therapy (HRT) in the form of estrogen alone or combined estrogen and progesterone formulations has been widely used to treat menopausal symptoms to improve women’s quality of life, control their climacteric symptoms and prevent osteoporosis. This study aims to investigate the knowledge and awareness of women towards menopausal hormone replacement therapy and its role in the management of menopause. A cross-
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Noble, Nikki. "Hormone replacement therapy: update and practical prescribing." Practice Nursing 32, no. 4 (2021): 148–56. http://dx.doi.org/10.12968/pnur.2021.32.4.148.

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Peri-menopause and menopause are a normal part of ageing. Nikki Noble gives an overview of hormone replacement therapy and practical prescribing tips Menopause is a physiological event of ovarian failure due to a loss of ovarian follicular activity. This leads to a lack of oestrogen, resulting in the cessation of menstruation and loss of reproductive function. This article discusses the symptoms of menopause and treatment with hormone replacement therapy. This includes practical prescribing, side effects and long-term benefits and risks. The current shortages of hormone replacement therapy are
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С., А. Шурпяк. "Principles of management of premature and surgical menopause in women with initial reproductive health problems." Reproductive Endocrinology, no. 41 (June 15, 2018): 48–54. https://doi.org/10.18370/2309-4117.2018.41.48-54.

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Menopausal hormone therapy remains the most effective treatment for vasomotor symptoms and genitourinary menopausal syndrome and has been shown to prevent bone loss and destruction. This circumstance makes it possible to consider menopausal hormone therapy as the main method for the treatment of premature and surgical menopause. It is important to note that despite the similarity of the long-term consequences bilateral oophorectomy and premature fading in ovarian function differ significantly in the dynamics of the hormones concentration decrease. The risks of menopausal hormone therapy vary d
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Romanenko, T. H., G. M. Zhaloba, and N. V. Yesyp. "Menopause hormone therapy (Literature review)." HEALTH OF WOMAN, no. 6(142) (July 29, 2019): 87–91. http://dx.doi.org/10.15574/hw.2019.142.87.

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Practitioners in the fields of obstetrics and gynecology get used to look at the women’s health from the point of view of maintaining her reproductive potential and assistance in its fulfillment. Less attention is paid to the problem of reproductive function`s descent. Common changes during the menopausal transition were out of specialists` focus and women were left with no choice but to deal with those problems on their own. Nevertheless, global tendency of population ageing and growing awareness about the importance of professional and cultural activities of these women makes it important to
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Batista, Nertan Ribeiro, Alessandra Honorato Aguiar, Ana Carolina da Ponte Cervo, et al. "HORMONE THERAPY DURING MENOPAUSE: BENEFITS AND INDICATIONS." Periódicos Brasil. Pesquisa Científica 3, no. 2 (2024): 264–80. http://dx.doi.org/10.36557/pbpc.v3i2.76.

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Descrever os benefícios e as principais indicações para o tratamento de reposição de hormônios durante a menopausa. Métodos: O presente estudo foi realizado mediante uma revisão sistemática da literatura, que aborda os benefícios da terapia hormonal na menopausa, por meio das bases de dados EMBASE e MEDLINE, através dos descritores DeCS/MeSH “Hormone Replacement Therapy” e “Menopause”utilizando o operador booleano “and” entre os descritores, como representado a seguir: “Hormone Replacement Therapy” and “Menopause”. Resultados/Discussão: Após as etapas descritas na metodologia do estudo, foram
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Noble, Nikki. "Hormone replacement therapy: update and practical prescribing." Journal of Prescribing Practice 2, no. 2 (2020): 91–97. http://dx.doi.org/10.12968/jprp.2020.2.2.91.

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Menopause is a physiological event of ovarian failure due to a loss of ovarian follicular activity. This leads to a lack of oestrogen, resulting in the cessation of menstruation and loss of reproductive function. This article discusses the symptoms of menopause and treatment with hormone replacement therapy. This includes practical prescribing, side effects and long term benefits and risks. The current shortages of hormone replacement therapy are also addressed. The aim of this article is to enable healthcare professionals to define menopause and gain an understanding of the symptoms associate
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Topo, Paivi, and Elina Hemminki. "Is menopause withering away?" Journal of Biosocial Science 27, no. 3 (1995): 267–76. http://dx.doi.org/10.1017/s0021932000022793.

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SummaryMenopause (cessation of menstruction) and the period surrounding it (climacterium) are often defined retrospectively by asking a woman the date of her last menstrual period (LMP). Based on a survey of 2000 women aged 45–64 in 1989 in Finland, this study examines (1) the relation between these definitions and women's own definitions of their climacteric status and of the cessation of menstruction and (2) the effect of menopausal and postmeno pausal hormone therapy and hysterectomy on the definition of menopause and climacterium. Agreement of the woman's own definition of her climacteric
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Leshchenko, O. Ya. "Menopausal transition: ambiguous definitions, diagnostic markers, and treatment strategies." Russian Journal of Woman and Child Health 8, no. 2 (2025): 106–13. https://doi.org/10.32364/2618-8430-2025-8-2-3.

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Premenopause (or menopausal transition preceding menopause) is characterized by gradual depletion of ovarian follicular reserve, altered response to gonadotropin hormones, significant fluctuations of hormone levels, and irregular menstruation. Typically, a clinician is faced with a number of issues and difficulties regarding diagnosis and therapy in such patients Aim: to discuss primary pathophysiological processes associated with the menopausal transition, as well as a place of non-hormonal treatment of comorbidities at this stage. A systematic search for guidelines, approaches, and consensus
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Vargas-Hernandez, Víctor Manuel. "Hormonal Therapy of Menopause and Mental Health." Journal of Obstetrics Gynecology and Reproductive Sciences 9, no. 3 (2025): 01–08. https://doi.org/10.31579/2578-8965/256.

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During the menopausal transition, which begins 4 to 6 years prior to stopping menstruation, women at this stage experience progressive changes in ovarian activity and physiological impairment of hypothalamic-pituitary-ovarian axis function associated with fluctuations in levels. hormonal; where they can suffer symptoms related to menopause such as vasomotor symptoms, sleep disorders, mood changes, memory problems and genitourinary syndrome of menopause. Neurological symptoms such as sleep disturbance and mood swings are the most important discomfort in the transition to menopause, which impact
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Smail, Linda, Ghufran A. Jassim, and Khawla I. Sharaf. "Emirati Women’s Knowledge about the Menopause and Menopausal Hormone Therapy." International Journal of Environmental Research and Public Health 17, no. 13 (2020): 4875. http://dx.doi.org/10.3390/ijerph17134875.

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The aim of this study was to investigate the knowledge of Emirati women aged 30–64 about menopause, menopausal hormone therapy (MHT), and their associated health risks, and additionally, to determine the relationships between Emirati women’s knowledge about menopause and their sociodemographic and reproductive characteristics. A community-based cross-sectional study was conducted of 497 Emirati women visiting five primary healthcare centers in Dubai. Data were collected using a questionnaire composed of sociodemographic and reproductive characteristics, menopause knowledge scale (MKS), and men
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Rodrigues, Marcio Alexandre H., Zilma Silveira Nogueira Reis, Ana Paula de Andrade Verona, et al. "Climacteric women’s perspectives on menopause and hormone therapy: Knowledge gaps, fears, and the role of healthcare advice." PLOS One 20, no. 5 (2025): e0316873. https://doi.org/10.1371/journal.pone.0316873.

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Objective This study aims to evaluate the knowledge, attitudes, and practices of Brazilian women regarding menopause, related symptoms, and the use of hormone therapy, including indications and contraindications. Methods A cross-sectional study was conducted between 2022/07/18 and 2023/10/01, involving women aged 40–65 years from various cities in Minas Gerais, São Paulo, and other regions of Brazil. A structured KAP (Knowledge, Attitudes, and Practices) Survey was used to assess sociodemographic characteristics, the prevalence of menopausal symptoms, and the participants’ knowledge and practi
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Khashukoeva, A. Z., E. A. Markova, M. V. Burdenko, L. A. Nosova, A. M. Solovyova, and E. A. Lukyanova. "Menopausal transition. Is it possible to delay the prescription of menopausal hormone therapy?" Meditsinskiy sovet = Medical Council, no. 15 (October 21, 2023): 126–33. http://dx.doi.org/10.21518/ms2023-342.

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After the end of the reproductive period, women spend a third of their lives in menopause. During this period, they experience a range of predictable symptoms and conditions associated with changing levels of sex hormones and aging of the body. The menopausal transition precedes menopause by several years and is usually characterized by irregular menstrual cycles, hot flashes and night sweats. After menopause, genitourinary symptoms predominate, including vulvovaginal atrophy and dryness and complaints associated with urinary disturbances: increased urinary frequency, urgency, and nocturia. Me
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Hernández, Víctor Manuel Vargas. "Long-Term Consequences of Menopause Victor manuel vargas hernandez Academic of the Mexican Academy of Surgery Secretary of the Mexican Association for the study of Climacteric." Obstetrics Gynecology and Reproductive Sciences 4, no. 3 (2020): 01–06. http://dx.doi.org/10.31579/2578-8965/094.

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The dramatic changes in sex hormone levels that occur during the transition to menopause and beyond are responsible for the long-term consequences, which are of primary importance to healthy aging in women. Sex hormones have a vital physiological role in maintaining the health and normal functioning of various organs; like bone, heart and brain. Disease activity is highly dependent on estrogen exposure; cardiovascular and musculoskeletal disorders frequently occur during postmenopause. Even cognitive decline is related to hypoestrogenism during the menopausal transition. Several lines of evide
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Watt, Fiona E. "Hand osteoarthritis, menopause and menopausal hormone therapy." Maturitas 83 (January 2016): 13–18. http://dx.doi.org/10.1016/j.maturitas.2015.09.007.

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Anagnostis, Ellena A. "Menopausal Hormone Therapy (MHT)." Journal of Pharmacy Practice 25, no. 3 (2012): 324–30. http://dx.doi.org/10.1177/0897190012442064.

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The perceptions of menopausal hormone therapy (MHT) have evolved considerably. Observational studies suggested that MHT could relieve vasomotor symptoms and prevent coronary heart disease (CHD). However, randomized controlled trials later showed no reduction in CHD and an increased risk of stroke. Subsequent analyses of these trials have shown that in women younger and closer to menopause, the risks associated with MHT may not be as great as originally thought. Several organizations, including the North American Menopause Society, the International Menopause Society, and the Endocrine Society,
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Yakushevskaya, O. V., S. V. Yureneva, M. V. Averyanova, et al. "Hormonal Correction of Menopausal Disorders in Patients with Burdened Oncological History of Serous Ovarian Cancer." Doctor.Ru 23, no. 2 (2024): 49–54. http://dx.doi.org/10.31550/1727-2378-2024-23-2-49-54.

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Aim. To provide clinicians with a systematic review of the available information regarding the use of menopausal hormone therapy in women with induced menopause due to combined treatment of ovarian cancer. Key points. Ovarian cancer is the eighth most common and seventh leading cause of cancer death. Menopausal hormone therapy is effective in correcting menopausal disorders, but its safety for patients who have had ovarian cancer is questioned. Conclusion. In patients with a history of ovarian cancer, menopausal hormone therapy is currently thought to improve overall survival and has little to
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Smith, R., and J. W. W. Studd. "A Pilot Study of the Effect upon Multiple Sclerosis of the Menopause, Hormone Replacement Therapy and the Menstrual Cycle." Journal of the Royal Society of Medicine 85, no. 10 (1992): 612–13. http://dx.doi.org/10.1177/014107689208501008.

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A questionnaire enquiring about changes in severity of symptoms of multiple sclerosis with the menstrual cycle, menopause and use of hormone replacement therapy was answered retrospectively by 11 premenopausal and 19 postmenopausal women. Eighty-two per cent of menopausal women reported an increase in severity premenstrually. Of the postmenopausal women 54% reported a worsening of symptoms with the menopause, and 75% of those who had tried hormone replacement therapy reported an improvement. The results of this pilot study indicate the need for further research to clarify the effects of the me
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Pirhadi, Roxanna, Vikram Sinai Talaulikar, Joseph Onwude, and Isaac Manyonda. "It is all in the name: The importance of correct terminology in hormone replacement therapy." Post Reproductive Health 26, no. 3 (2020): 142–46. http://dx.doi.org/10.1177/2053369120924175.

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The global increase in life expectancy to 74 years for women, while the median age of the menopause remains at 51 years, means that an increasing number of women will live a significant portion of their adult lives in the menopause. The WHI publications in 2003/4 reported on the dangers of hormone replacement therapy, in particular with respect to breast cancer and dementia risk. This resulted in a dramatic reduction in hormone replacement therapy prescription and use. However, the findings from the WHI studies have been re-appraised, and the new perspective is reflected in the guidance publis
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С., О. Шурпяк. "The effectiveness and safety of mht depending on the type, route of administration of estrogens, and the type of progestogen. Analysis of data from clinical trials and international recommendations." REPRODUCTIVE ENDOCRINOLOGY, no. 38 (December 28, 2017): 72–80. https://doi.org/10.18370/2309-4117.2017.38.72-80.

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The hormone therapy remains the most effective method for treating of the vasomotor symptoms and genitourinary syndrome in menopause. The evidence available to date suggests that for women younger than 60 and with a postmenopause no more than 10 years without contraindications, the benefits of administering systemic hormone therapy for the treatment of vasomotor symptoms, sleep disorders and prevention of bone loss exceed possible risks. In addition, the data about statistically significant reduction in all-cause mortality in women who initiate hormone therapy before the age of 60 and/or 10 ye
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Quaile, Heather, Christine Hart-Kress, and Jaclyn Piasta. "Understanding and Prescribing Menopausal Hormone Therapy for Vasomotor Symptoms." Clinical Journal for Nurse Practitioners in Women's Health 2, no. 1 (2025): 13–21. https://doi.org/10.1891/cjnpwh-2510.

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Menopausal hormone therapy is a critical intervention for managing menopause-related vasomotor symptoms. Nurse practitioners have a pivotal role in prescribing and managing menopausal hormone therapy. This article explores the pathophysiology of vasomotor symptoms, highlighting the efficacy of available forms of estrogen and progestogen in alleviating symptoms. It delves into the criteria for patient selection, emphasizing the importance of individualized treatment plans. The currently approved indications, safety profile, and potential risks and benefits of menopausal hormone therapy are exam
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О., О. Єфіменко. "MENOPAUSE. A PROBLEM THAT IS NOT OUT OF DATE. SPECIALIST COMMENT AND UPDATED DATA FROM THE NATIONAL CONSENSUS ON THE MANAGEMENT OF PATIENTS IN MENOPAUSE." REPRODUCTIVE ENDOCRINOLOGY, no. 51 (February 27, 2020): 72–88. https://doi.org/10.18370/2309-4117.2020.51.72-88.

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Climacteric is a physiological transition period in a woman’s life during which the reproductive system involutive processes against the age-related changes are dominated in the body, and characterized by reduction of menstrual and generative function due to genetically programmed cessation of ovarian function. There are 4 periods of menopause: menopausal transition period, menopause, perimenopause and menopause. This document provides an overview of existing diagnosis and treatment methods of menopausal disorders in women, proposed algorithms for diagnosis and treatment of this disease
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Martins, Vera, Nick Legroux, Monica Lascar, and Marion Gluck. "Compounded bioidentical HRT improves quality of life and reduces menopausal symptoms." Journal of Prescribing Practice 2, no. 7 (2020): 384–90. http://dx.doi.org/10.12968/jprp.2020.2.7.384.

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Bioidentical hormone replacement therapy, a form of hormone balancing and treatment that uses hormones identical to the ones naturally produced by the body, is an effective and well-tolerated method of hormone replacement therapy. The Marion Gluck Clinic conducted a small-scale study to assess the effectiveness of compounded bioidentical hormone replacement therapy treatment protocols and their impact on the quality of life of women experiencing symptoms of the menopause. Quality of life was assessed by completing the Greene Climacteric Scale questionnaire before and after bioidentical hormone
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Ou, Ying-Ju, Jia-In Lee, Shu-Pin Huang, Szu-Chia Chen, Jiun-Hung Geng, and Chia-Hung Su. "Association between Menopause, Postmenopausal Hormone Therapy and Metabolic Syndrome." Journal of Clinical Medicine 12, no. 13 (2023): 4435. http://dx.doi.org/10.3390/jcm12134435.

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(1) Background: We aimed to explore the associations between menopause, postmenopausal hormone therapy, and metabolic syndrome in a large community-based group of Asian women. (2) Methods: This is a cross-sectional study in which we enrolled women aged 30 to 70 years with sufficient information about menopausal status from the Taiwan Biobank. The definition for metabolic syndrome used in this study aligns with the Bureau of Health Promotion’s (Taiwan) proposed definition. (3) Results: A total of 17,460 women were recruited. The postmenopausal group had a higher metabolic syndrome prevalence (3
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&NA;. "Hormone Therapy After Menopause." Nurse Practitioner 28, no. 4 (2003): 55–56. http://dx.doi.org/10.1097/00006205-200304000-00021.

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Heutling, D., and H. Lehnert. "Hormone therapy and menopause." DMW - Deutsche Medizinische Wochenschrift 130, no. 13 (2005): 829–34. http://dx.doi.org/10.1055/s-2005-865097.

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Abitbol, Jean. "Hormone Replacement Therapy and Voice." Perspectives of the ASHA Special Interest Groups 4, no. 4 (2019): 607–14. http://dx.doi.org/10.1044/2019_pers-sig3-2018-0007.

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The purpose of this article is to update the management of the treatment of the female voice at perimenopause and menopause. Voice and hormones—these are 2 words that clash, meet, and harmonize. If we are to solve this inquiry, we shall inevitably have to understand the hormones, their impact, and the scars of time. The endocrine effects on laryngeal structures are numerous: The actions of estrogens and progesterone produce modification of glandular secretions. Low dose of androgens are secreted principally by the adrenal cortex, but they are also secreted by the ovaries. Their effect may incr
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Gava, Orsili, Alvisi, Mancini, Seracchioli, and Meriggiola. "Cognition, Mood and Sleep in Menopausal Transition: The Role of Menopause Hormone Therapy." Medicina 55, no. 10 (2019): 668. http://dx.doi.org/10.3390/medicina55100668.

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During the menopausal transition, which begins four to six years before cessation of menses, middle-aged women experience a progressive change in ovarian activity and a physiologic deterioration of hypothalamic-pituitary-ovarian axis function associated with fluctuating hormone levels. During this transition, women can suffer symptoms related to menopause (such as hot flushes, sleep disturbance, mood changes, memory complaints and vaginal dryness). Neurological symptoms such as sleep disturbance, “brain fog” and mood changes are a major complaint of women transitioning menopause, with a signif
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Diaz Brinton, Roberta. "Minireview: Translational Animal Models of Human Menopause: Challenges and Emerging Opportunities." Endocrinology 153, no. 8 (2012): 3571–78. http://dx.doi.org/10.1210/en.2012-1340.

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Increasing importance is placed on the translational validity of animal models of human menopause to discern risk vs. benefit for prediction of outcomes after therapeutic interventions and to develop new therapeutic strategies to promote health. Basic discovery research conducted over many decades has built an extensive body of knowledge regarding reproductive senescence across mammalian species upon which to advance animal models of human menopause. Modifications to existing animal models could rapidly address translational gaps relevant to clinical issues in human menopausal health, which in
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Cheng, Yu-Jung, Chieh-Hsin Lin, and Hsien-Yuan Lane. "From Menopause to Neurodegeneration—Molecular Basis and Potential Therapy." International Journal of Molecular Sciences 22, no. 16 (2021): 8654. http://dx.doi.org/10.3390/ijms22168654.

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The impacts of menopause on neurodegenerative diseases, especially the changes in steroid hormones, have been well described in cell models, animal models, and humans. However, the therapeutic effects of hormone replacement therapy on postmenopausal women with neurodegenerative diseases remain controversial. The steroid hormones, steroid hormone receptors, and downstream signal pathways in the brain change with aging and contribute to disease progression. Estrogen and progesterone are two steroid hormones which decline in circulation and the brain during menopause. Insulin-like growth factor 1
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Masibroda, N. G. "Menopause: not hormonal correction of disorders, as a personalized approach to improving a woman's quality of life." Reports of Vinnytsia National Medical University 27, no. 4 (2023): 678–83. http://dx.doi.org/10.31393/reports-vnmedical-2023-27(4)-26.

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Annotation. A review of scientific sources concerning the problem of menopausal syndrome and conditions associated with menopausal and perimenopausal disorders are presented below. Increasing the duration of life is important medical and socioeconomic significance for the country Menopausal hormone therapy (MHT) remains the most effective therapy for menopausal disorders. The vast majority of menopausal women remain alone with the existing manifestations and risks of this period for the rest of their lives. The goal of our work was the search, analysis and systematization of relevant scientifi
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Yureneva, S. V., and Ya A. Orlova. "Menopausal Transition — Time for Early and Effective Targeting of Cardiometabolic Risks." Doctor.Ru 22, no. 5 (2023): 40–48. http://dx.doi.org/10.31550/1727-2378-2023-22-5-40-48.

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Aim: to examine the features of risk factors and cardiovascular diseases in middle-aged women with a focus on period of the menopausal transition, which is of key importance to early prevention. Key Points. The studies showed distinct patterns of adverse changes in fat distribution, lipid profile, structural and functional indicators of vascular health during the menopausal transition regardless of aging. Conclusion. The cardiometabolic health of middle-aged women is systematically underestimated; the period of menopausal transition may be a critical window of opportunity for initiation of ear
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Henderson, VW, and BB Sherwin. "Surgical vs Natural Menopause: Cognitive Issues." Journal of SAFOMS 2, no. 1 (2014): 54–55. http://dx.doi.org/10.5005/jsafoms-2-1-54.

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Abstract Objective Women who undergo both natural and surgical menopause experience the loss of cyclic ovarian production of estrogen, but hormonal and demographic differences distinguish these two groups of women. Our objective was to review published evidence on whether the premature cessation of endogenous estrogen production in women who underwent a surgical menopause has deleterious consequences for cognitive aging and to determine whether consequences differ for women if they undergo natural menopause. Studies of estrogen-containing hormone therapy are relevant to this issue. Design We r
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Rynkiewicz, Agnieszka, Ewa Ferensztajn-Rochowiak, Rachel L. Moseley, et al. "Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report." Psychiatria i Psychologia Kliniczna 24, no. 4 (2025): 356–62. https://doi.org/10.15557/pipk.2024.0045.

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Considered a taboo topic in many societies, menopause in autistic women is still under-recognised, and little research addresses its impact. Existing studies suggest that this often-difficult transition period is associated with numerous unmet health needs and a frustrating lack of knowledge and support from healthcare professionals. Menopausal vasomotor symptoms, the hallmark of menopause, can intensify and worsen sensory sensitivities in many autistic women. We present the case of a 53-year-old Caucasian autistic woman without intellectual disability or other current psychiatric comorbiditie
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Sumarni, Deris, Nurul Badriyah, Satriyani Satriyani, Sarminah Sarminah, and Wisnu Probo Wijayanto. "Pengaruh Pemberian Kedelai (Glycine Max L.) Terhadap Keluhan Hot Flush pada Wanita Menopause di Puskesmas Tanjung Raja Kabupaten Lampung Utara." MAHESA : Malahayati Health Student Journal 4, no. 6 (2024): 2305–12. http://dx.doi.org/10.33024/mahesa.v4i6.14458.

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ABSTRACT The effects of hot flashes due to decreased esterogen levels can lead to osteoporosis, cardiovascular disease, and Alzheimer's dementia. Efforts to prevent the effects of hot flashes can use hormone therapy or hormone replacement is one of the most effective treatments to reduce menopausal symptoms. The purpose of the study was to determine the effect of soy on hot flush complaints in menopausal women at Tanjung Raja Health Center. This type of research is quantitative with a quasi-experimental research design with a one group pre-post test design. The population in this study were al
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Balan, Vera E., Elena V. Tikhomirova, Anastasia S. Zhuravel, Julia P. Titchenko, and Tatyana V. Lovygina. "New trends in current menopausal hormone therapy." Gynecology 23, no. 1 (2021): 33–36. http://dx.doi.org/10.26442/20795696.2021.1.200635.

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The article presents the results of recent studies on the effectiveness, safety and duration of menopausal hormone therapy (MHT). The main cardio-metabolic risk factors for cardiovascular diseases are formed in women precisely during the transition to menopause and are clearly associated with the appearance of vegetative menopausal symptoms and the development of endothelial dysfunction, which is a predictor of future serious health problems, especially cardiovascular diseases. The results of a number of epidemiological studies have shown that in women with severe climacteric manifestations, e
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Lersten, Ivy, Elizabeth Clain, and Nanette Santoro. "Use of Hormone Therapy in Women with Early Menopause and Premature Ovarian Insufficiency." Seminars in Reproductive Medicine 38, no. 04/05 (2020): 302–8. http://dx.doi.org/10.1055/s-0040-1721719.

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AbstractWomen with early menopause or primary ovarian insufficiency (POI) experience a menopausal state a decade or more earlier than their peers. The health consequences for POI are vast and varied with detrimental effects seen on neurological, psychological, bone, and cardiovascular systems. The risk profile of POI patients requires special attention, as they differ from a typical menopausal population. This review will explore the health risks associated with POI and examine the various treatment options and also the risks associated with hormone therapy. Given the risks and benefits, POI p
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Reeves, Alexis, Oscar Lopez, Michelle Shardell, and Michelle Odden. "THE ROLE OF REPRODUCTIVE AGING FOR ALZHEIMER’S DISEASE AND RELATED DEMENTIAS IN THE CARDIOVASCULAR HEALTH STUDY." Innovation in Aging 7, Supplement_1 (2023): 437. http://dx.doi.org/10.1093/geroni/igad104.1441.

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Abstract Most US individuals with ADRD are women. As early as midlife, Black individuals have nearly double the ADRD risk than Whites. Menopause occurs in midlife, accompanied by declines in potentially neuro-protective and cardio-protective hormones. Earlier menopause possibly means earlier exposure to decreased sex hormones, which increases ADRD risk. Surgical menopause via reproductive surgeries causes a sudden loss of hormones and could be a modifiable ADRD risk factor. We used data from 1,977 women prospectively followed for an average of 7.5 years, to determine if menopausal type (natura
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Cabral, Aléxia Alves, Vanessa Manso Torres, and Janaína Henriques Sobrinho Ribeiro. "Indicações, riscos e benefícios da reposição de hormônios bioidênticos na menopausa: uma revisão narrativa." Cadernos UniFOA 17, no. 48 (2022): 147–52. http://dx.doi.org/10.47385/cadunifoa.v17.n48.3592.

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RESUMOAtualmente, a terapia de reposição hormonal (TRH) na menopausa está indicada na presença de sintomas vasomotores e síndrome geniturinária da menopausa e para prevenção da perda de massa óssea e menopausa precoce. Após serem demonstrados riscos cardiovasculares e tromboembólicos em mulheres em uso da TRH, iniciaram-se novas buscas por alternativas de reposição hormonal. Essa revisão objetiva pontuar as indicações da TH para mulheres na menopausa e discutir sobre a atualização das novas tecnologias de TH, tratando-se dos hormônios bioidênticos (HB). Trata-se de uma revisão narrativa, reali
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John, Nimmy N., Riya Juan, and Manchu S. Danam. "An epidemiological study on knowledge, attitude and practice of married women about menopause and hormone replacement therapy." International Journal Of Community Medicine And Public Health 8, no. 5 (2021): 2299. http://dx.doi.org/10.18203/2394-6040.ijcmph20211749.

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Background: Women all over the world now have to spend almost 1/3rd of their lives in menopausal years. Therefore, menopause now is a concerning matter to maintain and improve women’s health. Hormone replacement therapy (HRT) is an effective treatment for menopausal symptoms. This study was conducted to determine knowledge, attitude and practice toward menopause HRT among women. Objective of the study was to determine the level of knowledge, attitude, and practice related to menopause and HRT among women.Methods: This cross-sectional study was carried out in May 2020 to July 2020 in a rural ar
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Van Schoor, Jacky. "Hot flushes." South African Family Practice 57, no. 6 (2015): 4. http://dx.doi.org/10.4102/safp.v57i6.4393.

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Vasomotor symptoms, such as hot flushes and night sweats, are considered to be the cardinal symptoms of menopause, and are experienced by most women. The physiology of hot flushes is not fully understood, and is likely to reflect the interplay between multiple central and peripheral physiological systems. Reproductive hormones play an integral role, as evidenced by the onset of vasomotor symptoms during the dramatic reproductive hormone changes of the menopausal transition, and by the efficacy of exogenous oestrogen in the treatment of hot flushes. Menopausal hormone therapy with oestrogen, an
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Chung, Bo Young, Chandler Johnson, Jin Seo Park, et al. "Patient-reported Impact of Menopause and Hormone Replacement Therapy on Psoriasis." Acta Dermato-Venereologica 105 (April 9, 2025): adv42843. https://doi.org/10.2340/actadv.v105.42843.

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Menopause’s impact on psoriasis remains unclear. This study’s aim was to gather information on patient perception of the impact of menopause and hormone replacement therapy (HRT) on psoriasis. This survey-based study analysed 139 postmenopausal women with psoriasis from the USA and South Korea. In the combined cohort, most women reported menopause either had no effect on their psoriasis (41.7%) or worsened their psoriasis (33.1%). In the combined cohort, a majority of women (73.4%) reported that there was no change in their psoriasis treatment with menopause. Of the women receiving HRT (n = 29
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Palacios, Santiago, John C. Stevenson, Katrin Schaudig, Monika Lukasiewicz, and Alessandra Graziottin. "Hormone therapy for first-line management of menopausal symptoms: Practical recommendations." Women's Health 15 (January 2019): 174550651986400. http://dx.doi.org/10.1177/1745506519864009.

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Hormone therapy use has undergone dramatic changes over the past 20 years. Widespread use of hormone therapy in the 1980s and 1990s came to an abrupt halt in the early 2000s after initial findings of the Women’s Health Initiative trial were published and the study was terminated. Since then, much has been learned about the characteristics of women most likely to benefit from hormone therapy. There is general agreement that women younger than 60 years or who initiate hormone therapy within 10 years of menopause onset gain short-term benefit in terms of symptomatic relief and long-term benefit i
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Sohail, Rubina. "Latest Recommendations for Hormone Replacement Therapy." Journal of SAFOMS 1, no. 2 (2013): 82–83. http://dx.doi.org/10.5005/jp-journals-10032-1019.

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ABSTRACT Menopause is an area of increasing importance. Menopause management and hormone replacement therapy have had their share of popularity and downward trends. At the peak of its popularity came the WHI trial resulting in a lot of confusion and worry leading to the diuse of HRT. However the recent guidelines published by the British Menopause Society have put HRT in perspective. How to cite this article Sohail R. Latest Recommendations for Hormone Replacement Therapy. J South Asian Feder Menopause Soc 2013;1(2):82-83.
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Honigberg, Michael C., Aniruddh P. Patel, Tim Lahm, et al. "Association of premature menopause with incident pulmonary hypertension: A cohort study." PLOS ONE 16, no. 3 (2021): e0247398. http://dx.doi.org/10.1371/journal.pone.0247398.

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Background Several forms of pulmonary hypertension (PH) disproportionately affect women. Animal and human studies suggest that estradiol exerts mixed effects on the pulmonary vasculature. Whether premature menopause represents a risk factor for PH is unknown. Methods and findings In this cohort study, women in the UK Biobank aged 40–69 years who were postmenopausal and had complete data available on reproductive history were included. Premature menopause, defined as menopause occurring before age 40 years. Postmenopausal women without premature menopause served as the reference group. The prim
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Karpenko, V. G., and Viktoriia Aleksandrovna Ilchenko. "PRINCIPLES OF HORMONE REPLACEMENT THERAPY IN WOMEN DURING MENOPAUSE." International Medical Journal, no. 2 (July 15, 2020): 29–31. http://dx.doi.org/10.37436/2308-5274-2020-2-6.

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One of the most pressing problems is the onset of menopause in the women over the age of 45 and the development of menopausal syndrome. Because a large number of women with severe menopausal symptoms does not receive adequate therapy and applies for the alternative ineffective ways to alleviate the condition, they should be informed about preventive measures and treatment of this syndrome. The paper describes in details the disorders that occur during menopause. Particular attention is paid to the examination of such women, the study of complaints related to the nervous and cardiovascular syst
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О., О. Єфіменко, and В. Занько О. "MENOPAUSE: FOCUS ON ADDITIONAL THERAPY OPPORTUNITIES. LITERATURE REVIEW." REPRODUCTIVE ENDOCRINOLOGY, no. 53 (June 30, 2020): 62–68. https://doi.org/10.18370/2309-4117.2020.53.62-68.

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About 10% of the world's populations are menopausal women. This period coincides with the most active social and professional activities of almost every woman. In addition to typical manifestations, this age stage is characterized by menopausal metabolic syndrome, which is caused by estrogen deficiency and is found in 35–49% of women in older age groups. Modern approaches to the treatment and prevention of menopausal disorders include following principles: lifestyle changes, menopausal hormone therapy (MHT), non-hormonal therapy (drugs with hormone-like effects, phytoestrogens, selec
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Schulkin, Jay. "Hormone Therapy, Dilemmas, Medical Decisions." Journal of Law, Medicine & Ethics 36, no. 1 (2008): 73–88. http://dx.doi.org/10.1111/j.1748-720x.2008.00239.x.

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The question of why women, in consultation with their physicians, should choose hormone therapy (HT) in response to menopause represents a renewed controversy at the beginning of the new century. Conflicting messages regarding the health risks and benefits of HT have been conveyed in the mainstream media, especially information in the media regarding the results of large-scale studies of the health impact of hormone therapy. Women who have been on one or another of the hormone replacement regimes have been forced to reconsider continuing on HT. Doctors who suggest these hormones to their patie
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Mahmud, Khalid. "Natural hormone therapy for menopause." Gynecological Endocrinology 26, no. 2 (2009): 81–85. http://dx.doi.org/10.3109/09513590903184134.

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