Auswahl der wissenschaftlichen Literatur zum Thema „Minibioreactor“
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Zeitschriftenartikel zum Thema "Minibioreactor":
Vallejos, Jose R., Yordan Kostov, Arun Ram, Joseph A. French, Mark R. Marten und Govind Rao. „Optical analysis of liquid mixing in a minibioreactor“. Biotechnology and Bioengineering 93, Nr. 5 (2006): 906–11. http://dx.doi.org/10.1002/bit.20785.
Kumar, Arul, und M. N. Sivakumar. „Different Mechanized Minibioreactor Framework for Multifunctional Screening in Biotechnology“. Research Journal of Pharmacy and Technology 11, Nr. 12 (2018): 5379. http://dx.doi.org/10.5958/0974-360x.2018.00981.2.
Gu, Man Bock, Geun Cheol Gil und Joong Hyun Kim. „A two-stage minibioreactor system for continuous toxicity monitoring“. Biosensors and Bioelectronics 14, Nr. 4 (April 1999): 355–61. http://dx.doi.org/10.1016/s0956-5663(99)00017-2.
Rodriguez, Joaquín V., María Dolores Pizarro, Angel L. Scandizzi, Edgardo E. Guibert, Luciana L. Almada und María E. Mamprin. „Construction and Performance of a Minibioreactor Suitable as Experimental Bioartificial Liver“. Artificial Organs 32, Nr. 4 (April 2008): 323–28. http://dx.doi.org/10.1111/j.1525-1594.2007.00435.x.
Soley, A., A. Fontova, J. Gálvez, E. Sarró, M. Lecina, R. Bragós, J. J. Cairó und F. Gòdia. „Development of a simple disposable six minibioreactor system for suspension mammalian cell culture“. Process Biochemistry 47, Nr. 4 (April 2012): 597–605. http://dx.doi.org/10.1016/j.procbio.2011.12.022.
Lee, J. H., C. H. Song, B. C. Kim und M. B. Gu. „Application of a multi-channel system for continuous monitoring and an early warning system“. Water Science and Technology 53, Nr. 4-5 (01.02.2006): 341–46. http://dx.doi.org/10.2166/wst.2006.139.
Zou, Xiang, Xia Guo und Min Sun. „pH control strategy in a shaken minibioreactor for polysaccharide production by medicinal mushroom Phellinus linteus and its anti-hyperlipemia activity“. Bioprocess and Biosystems Engineering 32, Nr. 2 (28.06.2008): 277–81. http://dx.doi.org/10.1007/s00449-008-0241-5.
Kumar, Sathish, Christoph Wittmann und Elmar Heinzle. „Review: Minibioreactors“. Biotechnology Letters 26, Nr. 1 (Januar 2004): 1–10. http://dx.doi.org/10.1023/b:bile.0000009469.69116.03.
Aboka, Fredrick O., Wouter A. Winden, Mashego M. Reginald, Walter M. Gulik, Marco Berg, Arthur Oudshoorn und Joseph J. Heijnen. „Identification of informative metabolic responses using a minibioreactor: a small step change in the glucose supply rate creates a large metabolic response in Saccharomyces cerevisiae“. Yeast 29, Nr. 3-4 (März 2012): 95–110. http://dx.doi.org/10.1002/yea.2892.
Coufalík, Pavel, Peter Váczi, Ondřej Zvěřina, Kateřina Trnková, Kateřina Skácelová, Miloš Barták und Josef Komárek. „Nitrate and ammonium ions contents in field minibioreactors with Antarctic freshwater autotrophs“. Czech Polar Reports 3, Nr. 2 (01.06.2013): 196–207. http://dx.doi.org/10.5817/cpr2013-2-20.
Dissertationen zum Thema "Minibioreactor":
Jakešová, Michaela. „Vývoj minibioreaktoru pro mikrobiální biotechnologie“. Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-449744.
Soley, Astals Albert. „Disseny i desenvolupament de minibioreactors amb instrumentació per a l’optimització de cultius cel· lulars“. Doctoral thesis, Universitat Autònoma de Barcelona, 2010. http://hdl.handle.net/10803/48713.
The research and development in the biotechnological field generates a vast amount of new cells and products of interest for various economical sectors. In this framework, it is needed to explore, in reasonable times and with automated means, the potential of the generated, regarding its growth, productivity and quality of the obtained products. Establishing the culture conditions of a productive process based in cells required accomplishing several stages: from the selection of the cellular system and the realization of molecular biology works to the achievement of a bioprocess having optimized conditions. In this work the design and development of a multiple minibioreactor system is presented, having the aim of fastening the first stages of the bioprocess development, in a systematic way, and acquiring relevant information regarding the evolution of the main culture variables, making possible the realization of various sorts of experiments such as clone selections, the characterization of its culture performance, the culture medium optimization, and the toxicological evaluation of molecules. The design of the multiple minibioreactor system combines the benefits of the usual small scale culture systems, such as the consumption of small amounts of medium ad the capability of performing multiple parallel cultures, and the benefits of larger scale culture systems, such as the homogeneity and the knowledge of the main culture variables, ensuring these do not have limiting values. Consequently, special attention has been paid to the development of a stirring system ensuring the homogeneity of the bioreactor content and to the monitoring systems allowing the characterization of the cell growth and metabolism, which permits having sufficient data to upscale the process, minimizing the risks of such duty. Before starting the technological development stage, a preliminary study has been done with the aim of identifying and characterizing the required equipment features, regarding the auxiliary equipment supplying the culture conditions (stirring, aeration), and also regarding the potentiality and limitations of the monitoring systems. The main culture environmental variables to be monitored are pH and dissolved oxygen, whereas to monitor growth cellular concentration is to be followed. Additionally, oxygen consumption is to be used as a metabolic indicator, and pH is also a variable from which it can be obtained interesting information regarding culture physiology and metabolism. Given the different design possibilities for the required technologies depending on the cellular models to be used, one of them, precisely mammalian cells have been chosen. Thus, the detailed design and development of the minibioreactor system has been directed towards applications with such cellular model, paying special attention to the characteristic requirements of mammalian cells (basically agitation and aeration), and to the hydrodynamic characteristics of the system. On the other hand, also in the technological development chapter, techniques to monitor cell concentration, pH, dissolved oxygen and oxygen consumption have been implemented. Once the technological development has been completed and the required functionalities validated, in the last part of this work various cultures are performed with the aim of evaluating the culture reproducibility, and the information obtained by the equipment as it is used for culturing a certain cell line at various conditions. Finally, it is also interesting to underline the potential fields of development based on this work: new features of the multiple minibioreactor system, such as the pH and dissolved oxygen controls, and the potential use of the system for the culture of bacteria and yeast.
Silva, João Fernando de Andrade Cardoso da. „Mixing characterization in novel high throughput minibioreactors: scale-down modeling from bench scale“. Dissertação, 2010. http://hdl.handle.net/10216/58031.
Silva, João Fernando de Andrade Cardoso da. „Mixing characterization in novel high throughput minibioreactors: scale-down modeling from bench scale“. Master's thesis, 2010. http://hdl.handle.net/10216/58031.
Buchteile zum Thema "Minibioreactor":
Fontova, A., A. Soley, E. Sarró, J. Gálvez, R. Bragos, J. J. Cairó und F. Gòdia. „A Multiple Minibioreactor Platform for Parallel and Automated Mammalian Cell Culture“. In Cells and Culture, 289–93. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-3419-9_51.
De León, Antonio, Héctor Mayani und Octavio T. Ramírez. „Design, characterization and application of a minibioreactor for the culture of human hematopoietic cells under controlled conditions“. In Current Applications of Cell Culture Engineering, 127–38. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4786-6_14.
Auchtung, Jennifer M., Catherine D. Robinson, Kylie Farrell und Robert A. Britton. „MiniBioReactor Arrays (MBRAs) as a Tool for Studying C. difficile Physiology in the Presence of a Complex Community“. In Methods in Molecular Biology, 235–58. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6361-4_18.
„A minibioreactor for developing “perfused” capillaries in cardiomyocyte aggregates“. In Innovative Developments in Design and Manufacturing, 45–48. CRC Press, 2009. http://dx.doi.org/10.1201/9780203859476-9.
Mironov, V., V. Kasyanov, K. Leong, D. Liu und C. Chua. „A minibioreactor for developing “perfused” capillaries in cardiomyocyte aggregates“. In Innovative Developments in Design and Manufacturing. CRC Press, 2009. http://dx.doi.org/10.1201/9780203859476.ch3.
Konferenzberichte zum Thema "Minibioreactor":
Fontova, A., A. Soley, J. Galvez, E. Sarro, M. Lecina, J. Rosell, P. Riu, J. Cairo, F. Godia und R. Bragos. „Multiple automated minibioreactor system for multifunctional screening in biotechnology“. In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.4397480.
Fontova, A., A. Soley, J. Galvez, E. Sarro, M. Lecina, J. Rosell, P. Riu, J. Cairo, F. Godia und R. Bragos. „Multiple automated minibioreactor system for multifunctional screening in biotechnology“. In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.260628.