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1

Johansson, J., W. A. Hapsari, S. Kelley, and G. Bodog. "Minimization of drive tests in 3GPP release 11." IEEE Communications Magazine 50, no. 11 (2012): 36–43. http://dx.doi.org/10.1109/mcom.2012.6353680.

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2

Yahya, Ahmad, Ata ul Razzaq Khan, Wahab Usaid Naeem, Sajid Bashir, Babar Murtaza, and Aqeel Aslam. "COST-MINIMIZATION ANALYSIS OF VARIOUS PHARMACEUTICAL ALTERNATIVES OF CLOPIDOGREL BISULFATE." Pakistan Journal of Pharmaceutical Research 2, no. 1 (2016): 37. http://dx.doi.org/10.22200/pjpr.2016137-41.

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Heart disease is widespread, and accounts for a quarter of all deaths in the US. Clopidogrel is used extensively for various cardiac conditions but has a high price. Cost-minimization analysis (CMA) differentiates alternative therapies based on price, given that all of the interventions have exactly the same health effects and must be bioequivalent when it comes to health benefits and adverse effects. Dissolution studies, using four marketed products, were conducted using a six stage, type II dissolution apparatus. Samples were analyzed at 240nm using a UV-VIS spectrophotometer. Concentration
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3

Koulamas, Christos, and George J. Kyparisis. "Makespan minimization on uniform parallel machines with release times." European Journal of Operational Research 157, no. 1 (2004): 262–66. http://dx.doi.org/10.1016/s0377-2217(03)00243-1.

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4

Zhang, Steven, Molly Vora, Alex H. S. Harris, Laurence Baker, Catherine Curtin, and Robin N. Kamal. "Cost-Minimization Analysis of Open and Endoscopic Carpal Tunnel Release." Journal of Bone and Joint Surgery 98, no. 23 (2016): 1970–77. http://dx.doi.org/10.2106/jbjs.16.00121.

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5

Cheng, T. C. Edwin, Mikhail Y. Kovalyov, and Natalia V. Shakhlevich. "Scheduling with controllable release dates and processing times: Makespan minimization." European Journal of Operational Research 175, no. 2 (2006): 751–68. http://dx.doi.org/10.1016/j.ejor.2005.06.021.

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6

Kuz’min, A. M. "Minimization of Heat-Release Distribution Instability in Burning Nuclear Fuel." Atomic Energy 124, no. 6 (2018): 387–91. http://dx.doi.org/10.1007/s10512-018-0427-0.

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7

Happach, Felix. "Makespan minimization with OR-precedence constraints." Journal of Scheduling 24, no. 3 (2021): 319–28. http://dx.doi.org/10.1007/s10951-021-00687-6.

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AbstractWe consider a variant of the NP-hard problem of assigning jobs to machines to minimize the completion time of the last job. Usually, precedence constraints are given by a partial order on the set of jobs, and each job requires all its predecessors to be completed before it can start. In this paper, we consider a different type of precedence relation that has not been discussed as extensively and is called OR-precedence. In order for a job to start, we require that at least one of its predecessors is completed—in contrast to all its predecessors. Additionally, we assume that each job ha
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8

Haidar, Ziyad S. "Mathematical Modeling for Pharmacokinetic Predictions from Controlled Drug Release Nano Systems: A Comparative Parametric Study." Biomedical and Pharmacology Journal 11, no. 4 (2018): 1801–6. http://dx.doi.org/10.13005/bpj/1552.

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In the present work, several mathematical models well-known in the literature for simulating drug release kinetics are compared using available experimental data sets obtained in real systems with different drugs and nano-sized carriers. Herein, the χ2 minimization method, is employed concluding that the Korsmeyer-Peppas model provides the best-fit in all cases. Hence, (i) better understanding of the exact mass transport mechanism(s) involved in drug(s) release, and (ii) quantitative prediction of the drug release kinetics, can be computed.
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9

Hezaveh, Hadi, and Ida Idayu Muhamad. "Controlled drug release via minimization of burst release in pH-response kappa-carrageenan/polyvinyl alcohol hydrogels." Chemical Engineering Research and Design 91, no. 3 (2013): 508–19. http://dx.doi.org/10.1016/j.cherd.2012.08.014.

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10

Liu, Lu, Yang Tao Xu, Na Yin, and Ji Bo Wang. "Single Machine Group Scheduling Problem with Deteriorating Jobs and Release Dates." Applied Mechanics and Materials 513-517 (February 2014): 2145–48. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.2145.

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The paper deals with a single machine scheduling problem with deteriorating jobs and group technology (GT) assumption. By deteriorating jobs and group technology assumption, we mean that the group setup times and job processing times are both simple linear functions of their starting times. We show that the makespan minimization problem with release dates can be solved in polynomial time.
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11

Cheng, T. C. Edwin, Mikhail Y. Kovalyov, and Natalia V. Shakhlevich. "Scheduling with controllable release dates and processing times: Total completion time minimization." European Journal of Operational Research 175, no. 2 (2006): 769–81. http://dx.doi.org/10.1016/j.ejor.2005.06.072.

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12

Hsu, Chia-Chang, Owen RT Thomas, and Tim W. Overton. "Periplasmic expression in and release of Fab fragments fromEscherichia coliusing stress minimization." Journal of Chemical Technology & Biotechnology 91, no. 3 (2015): 815–22. http://dx.doi.org/10.1002/jctb.4672.

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13

Knees, Dorothee, and Matteo Negri. "Convergence of alternate minimization schemes for phase-field fracture and damage." Mathematical Models and Methods in Applied Sciences 27, no. 09 (2017): 1743–94. http://dx.doi.org/10.1142/s0218202517500312.

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We consider time-discrete evolutions for a phase-field model (for fracture and damage) obtained by alternate minimization schemes. First, we characterize their time-continuous limit in terms of parametrized [Formula: see text]-evolutions, introducing a suitable family of “intrinsic energy norms”. Further, we show that the limit evolution satisfies Griffith’s criterion, for a phase-field energy release, and that the irreversibility constraint is thermodynamically consistent.
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14

Solovova, Natalya V., Natalya N. Kapustina, and Olga Yu Kalmykova. "Assessment of personnel risks of the personnel release process." Vestnik of Samara University. Economics and Management 14, no. 3 (2023): 188–94. http://dx.doi.org/10.18287/2542-0461-2023-14-3-188-194.

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The problem of timely prevention of personnel risks is relevant for large industrial organizations due to a decrease in the comfort index of the organizational environment due to the socio-economic situation and ongoing organizational changes. In the article, the authors consider the problem of improving the methods of the process of releasing (dismissing) the personnel of an industrial organization in order to prevent personnel risks in modern socio-economic conditions. The purpose of the study is to develop scientific and practical recommendations for the implementation of methods for identi
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15

Wang, Dan, and Na Yin. "Single Machine Scheduling with Resource-Dependent Ready Times and Positional Deterioration Effect." Applied Mechanics and Materials 481 (December 2013): 207–11. http://dx.doi.org/10.4028/www.scientific.net/amm.481.207.

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The paper deals with the single machine scheduling problems with positional deterioration effect. It is assumed that the release time of a job is a positive strictly decreasing continuous function of the amount of consumed resource. We present a polynomial solution for the total resource consumption minimization problem under the constraint that the makespan does not exceed a given limit.
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16

Surender Reddy, S. "Multi-objective optimization considering cost, emission and loss objectives using PSO and fuzzy approach." International Journal of Engineering & Technology 7, no. 3 (2018): 1552. http://dx.doi.org/10.14419/ijet.v7i3.11203.

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A novel approach to solve multi-objective optimization (MOO) problem which aims at minimizing fuel cost, emission release and real power loss of the system simultaneously has been proposed in this paper. Conventional minimum cost operation cannot be the only basis for generation dispatch; emission release minimization and loss minimization must also be taken care of. Power system must be operated in such a way that both active and reactive powers are optimized simultaneously. Reactive powers should be optimized to provide better volt-age profile as well as to reduce system losses. In this pape
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17

Vlachou, Marilena, Efthymia Geraniou, and Angeliki Siamidi. "Modified release of furosemide from Eudragits® and poly(ethylene oxide)-based matrices and dry-coated tablets." Acta Pharmaceutica 70, no. 1 (2020): 49–61. http://dx.doi.org/10.2478/acph-2020-0010.

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AbstractModified release of furosemide from tablet formulations is preferred by patients, because of physiological problems, acute diuresis being the most serious, compared to the forms designed for immediate release. With this in view, we aimed at achieving furosemide’s longer gastric retention and waste minimization by preparing matrix and compression coated tablets incorporating different grades of Eudragit® and poly(ethylene oxide) (PEO), polyvinylpyrrolidone (PVP) and lactose monohydrate. Dissolution profiles of the new formulations were compared with that of the main stream drug Lasix®,
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18

Bai, Danyu, Xiaoyuan Bai, Jie Yang, et al. "Minimization of maximum lateness in a flowshop learning effect scheduling with release dates." Computers & Industrial Engineering 158 (August 2021): 107309. http://dx.doi.org/10.1016/j.cie.2021.107309.

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19

TOGO, Norihisa, Toru EGUCHI, and Takeshi MURAYAMA. "S1440104 Lead Time Minimization Using a Release Time Decision Method Based on Scheduling." Proceedings of Mechanical Engineering Congress, Japan 2015 (2015): _S1440104——_S1440104—. http://dx.doi.org/10.1299/jsmemecj.2015._s1440104-.

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20

M. E. Teske and H. W. Thistle. "POULTRY A SIMULATION OF RELEASE HEIGHT AND WIND SPEED EFFECTS FOR DRIFT MINIMIZATION." Transactions of the ASAE 42, no. 3 (1999): 583–91. http://dx.doi.org/10.13031/2013.13218.

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21

Pal, Himanshu, and Vikas Kumar Sharma. "Development, Optimization & Evaluation Of Solid Lipid Nanoparticles Of Celecoxib." Journal of Neonatal Surgery 14, no. 15S (2025): 704–19. https://doi.org/10.63682/jns.v14i15s.3576.

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Celecoxib belongs to the category of nonsteroidal anti-inflammatory drug having poor oral bioavailability caused by the first-pass metabolism. Work in present to improve the oral bioavailability of celecoxib by incorporating into SLNs. Several celecoxib loaded formulation of SLNs were formulated using lipid by a method known as solvent emulsification-diffusion method and optimization is done by central composite drug design. The physical compatibility study of drug excipients was done by FTIR. Optimizes celecoxib loaded-SLNs have particle size in range of 314 nm with entrapment efficiency vary
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22

Karmakar, B., MM Rahman, MAR Sarkar, et al. "Adoption Lag Minimization for Increasing Rice Yield." Bangladesh Rice Journal 25, no. 1 (2021): 75–88. http://dx.doi.org/10.3329/brj.v25i1.55180.

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Sustainable adoption of promising technology leads to increase yield and productivity of rice significantly. Yield gap reduction through minimization of adoption cycle of rice technologies is essential to increase food security of Bangladesh. Adoption of promising rice variety required 16±3 years to reach its adoption peak at farm level following the existing dissemination protocol. The specific objective is to find out the ways and means to curtail adoption lag of variety, management practices and rice based technologies for sustainable food security of Bangladesh. The study is accomplished a
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23

Xu, Yuhan, Sheng Fang, Xinwen Dong, and Shuhan Zhuang. "A spatiotemporally separated framework for reconstructing the sources of atmospheric radionuclide releases." Geoscientific Model Development 17, no. 12 (2024): 4961–82. http://dx.doi.org/10.5194/gmd-17-4961-2024.

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Abstract. Determining the source location and release rate are critical tasks when assessing the environmental consequences of atmospheric radionuclide releases, but they remain challenging because of the huge multi-dimensional solution space. We propose a spatiotemporally separated two-step framework that reduces the dimension of the solution space in each step and improves the source reconstruction accuracy. The separation process applies a temporal sliding-window average filter to the observations, thereby reducing the influence of temporal variations in the release rate on the observations
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24

Kachru, N., and S. S. Sansgiry. "Once-a-day extended-release versus two-times-daily immediate-release methylphenidate for the treatment of adhd - A cost minimization study." Value in Health 16, no. 3 (2013): A62. http://dx.doi.org/10.1016/j.jval.2013.03.1586.

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25

Baker, S., S. C. Brooks, and D. M. Walker. "The Release of Residual Monomeric Methyl Methacrylate from Acrylic Appliances in the Human Mouth: An Assay for Monomer in Saliva." Journal of Dental Research 67, no. 10 (1988): 1295–99. http://dx.doi.org/10.1177/00220345880670101001.

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A gas-liquid chromatography assay has been developed for the estimation of methyl methacrylate monomer (MMA) in whole saliva, with a lower limit of detection in the order of 1μg/mL. Healthy human dentate subjects wore recently made autopolymerized or heat-polymerized polymethyl methacrylate (PMMA) palatal appliances. MMA released into saliva was detected for up to one week after insertion of autopolymerized appliances, with a maximum concentration of 45 μg/mL in whole saliva or 180 μg/mL in the salivary film on the fitting surface. The MMA was not detected in blood or urine. MMA was also prese
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26

Akande, Saheed, Ayodeji Emmanuel Oluleye, and Elkanah Oyetunji. "Minimization of Total Tardiness and Total Flowtime on Single Machine with Non-Zero Release Dates." International Journal of Engineering Research in Africa 29 (March 2017): 154–64. http://dx.doi.org/10.4028/www.scientific.net/jera.29.154.

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This paper considers the bicriteria scheduling problem of minimizing the composite function of total tardiness and total flow time on single machine with non-zero release dates. The problem is strongly Non Polynomial (NP). Thus, two heuristics SA7 and SA8 were proposed to solve the problem. The generalized algorithm and the branch and bound procedure were also implemented. The four solution methods were tested on a total of 800 randomly generated problems ranging from 5 to 1000 jobs. Results based on effectiveness and efficiency show that the SA7 heuristic is the most suited solution method to
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27

Kononov, Alexander, and Maxim Sviridenko. "A linear time approximation scheme for makespan minimization in an open shop with release dates." Operations Research Letters 30, no. 4 (2002): 276–80. http://dx.doi.org/10.1016/s0167-6377(02)00115-3.

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28

Köksoy, Gözde T., and F. Dilek Sanin. "Effect of digester F/M ratio on gas production and sludge minimization of ultrasonically treated sludge." Water Science and Technology 62, no. 7 (2010): 1510–17. http://dx.doi.org/10.2166/wst.2010.447.

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Sludge pretreatment by mechanical, chemical or thermal methods before anaerobic digestion has been applied to increase the digestability of excess sludge. Pretreatment processes rely on their ability to disrupt cell membranes and to release organic materials from the cells into the aqueous phase. Pretreatment by mechanical disintegration has grown rapidly in recent years in parallel with the advances in technology. Ultrasonic sludge disintegration –one of the most commonly used mechanical pretreatment methods- enables the occurrence of cavitation bubbles for the break-up of microorganism cells
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29

Parejiya, P. B., B. S. Barot, and P. K. Shelat. "Development of Prolonged Delivery of Tramadol and Dissolution Translation by Statistical Data Treatment." International Journal of Pharmaceutical Sciences and Nanotechnology 4, no. 1 (2011): 1331–37. http://dx.doi.org/10.37285/ijpsn.2011.4.1.5.

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The present study was carried out to fabricate a prolonged design for tramadol using Kollidon SR (Polyvinyl acetate and povidone based matrix retarding polymer). Matrix tablet formulations were prepared by direct compression of Kollidon SR of a varying proportion with a fixed percentage of tramadol. Tablets containing a 1:0.5 (Drug: Kollidon SR) ratio exhibited a rapid rate of drug release with an initial burst effect. Incorporation of more Kollidon SR in the matrix tablet extended the release of drug with subsequent minimization of the burst effect as confirmed by the mean dissolution time, d
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30

LAZZARONI, GIULIANO, and RODICA TOADER. "A MODEL FOR CRACK PROPAGATION BASED ON VISCOUS APPROXIMATION." Mathematical Models and Methods in Applied Sciences 21, no. 10 (2011): 2019–47. http://dx.doi.org/10.1142/s0218202511005647.

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In the setting of antiplane linearized elasticity, we show the existence of quasistatic evolutions of cracks in brittle materials by using a vanishing viscosity approach, thus taking into account local minimization. The main feature of our model is that the path followed by the crack need not be prescribed a priori: indeed, it is found as the limit (in the sense of Hausdorff convergence) of curves obtained by an incremental procedure. The result is based on a continuity property for the energy release rate in a suitable class of admissible cracks.
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31

Putranto, Utama, Retno Intani, and Mediana Handayani. "ANALISIS PRESS RELEASE SEBAGAI STRATEGI KRISIS “PENCURIAN DATA INFORMASI PENGGUNA TOKOPEDIA”." Jurnal Dinamika Ilmu Komunikasi 9, no. 2 (2023): 67–74. http://dx.doi.org/10.32509/dinamika.v9i2.4283.

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Penelitian ini bertujuan untuk menganalisis strategi image repair atau perbaikan citra yang dilakukan Tokopedia pada kasus pencurian data informasi pengguna Tokopedia. Penelitian ini merupakan penelitian deskriptif kualitatif dengan pendekatan studi kasus. Penelitian ini menggunakan teori Image Repair atau perbaikan citra. Teknik untuk mengecek keabsahan data yang digunakan pada penelitian ini adalah teknik triangulasi sumber data. Data penelitian mengacu pada 3 (tiga) rilis pers yang dipublikasikan melalui kanal pusat informasi media Tokopedia dan Kominfo serta hasil wawancara dengan ahli kom
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32

Kacem, Imed, Nizar Souayah, and Mohamed Haouari. "Branch-and-bound algorithm for total weighted tardiness minimization on parallel machines under release dates assumptions." RAIRO - Operations Research 46, no. 2 (2012): 125–47. http://dx.doi.org/10.1051/ro/2012010.

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33

Rudek, R. "Computational complexity of the single processor makespan minimization problem with release dates and job-dependent learning." Journal of the Operational Research Society 65, no. 8 (2014): 1170–76. http://dx.doi.org/10.1057/jors.2013.19.

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34

Lin, Shih-Wei, Zne-Jung Lee, Kuo-Ching Ying, and Chung-Cheng Lu. "Minimization of maximum lateness on parallel machines with sequence-dependent setup times and job release dates." Computers & Operations Research 38, no. 5 (2011): 809–15. http://dx.doi.org/10.1016/j.cor.2010.09.020.

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35

Archetti, Claudia, Dominique Feillet, Andrea Mor, and M. Grazia Speranza. "An iterated local search for the Traveling Salesman Problem with release dates and completion time minimization." Computers & Operations Research 98 (October 2018): 24–37. http://dx.doi.org/10.1016/j.cor.2018.05.001.

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36

Panotopoulos, Grigorios P., and Ziyad S. Haidar. "Mathematical Modeling for Pharmaco-Kinetic and -Dynamic Predictions from Controlled Drug Release NanoSystems: A Comparative Parametric Study." Scientifica 2019 (January 6, 2019): 1–5. http://dx.doi.org/10.1155/2019/9153876.

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Predicting pharmacokinetics, based on the theory of dynamic systems, for an administered drug (whether intravenously, orally, intramuscularly, etc.), is an industrial and clinical challenge. Often, mathematical modeling of pharmacokinetics is preformed using only a measured concentration time profile of a drug administered in plasma and/or in blood. Yet, in dynamic systems, mathematical modeling (linear) uses both a mathematically described drug administration and a mathematically described body response to the administered drug. In the present work, we compare several mathematical models well
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37

Hiley, Michael J., and Maurice R. Yeadon. "The Effect of Cost Function on Optimum Technique of the Undersomersault on Parallel Bars." Journal of Applied Biomechanics 28, no. 1 (2012): 10–19. http://dx.doi.org/10.1123/jab.28.1.10.

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The undersomersault, or felge, to handstand on parallel bars has become an important skill in Men’s Artistic Gymnastics as it forms the basis of many complex variations. To receive no deductions from the judges, the undersomersault must be performed without demonstrating the use of strength to achieve the final handstand position. Two male gymnasts each performed nine undersomersaults from handstand to handstand while data were recorded using an automatic motion capture system. The highest and lowest scoring trials of each gymnast, as determined by four international judges, were chosen for fu
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38

Karaduman, Alper, Huseyin Lekesiz, and Ali Riza Yildiz. "Minimization of release bearing load loss in a clutch system for high-speed rotations using the differential evolution algorithm." Materials Testing 64, no. 11 (2022): 1627–35. http://dx.doi.org/10.1515/mt-2022-0111.

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Abstract Diaphragm spring is a critical part of a clutch system because it affects the release bearing load characteristics directly and that determines the quality of disengagement. Bearing load provides required clamping for coupling however it may vary significantly during the engagement/disengagement process. A significant drop in bearing load may be experienced especially for high engine velocities for certain bearing displacement due to centrifugal forces occurring on the fingertips of diaphragm springs. The falling in release bearing load is undesirable for comfortable driving and clutc
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39

Chupin, Maxime, Thomas Haberkorn, and Emmanuel Trélat. "Low-thrust Lyapunov to Lyapunov and Halo to Halo missions with L2-minimization." ESAIM: Mathematical Modelling and Numerical Analysis 51, no. 3 (2017): 965–96. http://dx.doi.org/10.1051/m2an/2016044.

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In this work, we develop a new method to design energy minimum low-thrust missions (L2-minimization). In the Circular Restricted Three Body Problem, the knowledge of invariant manifolds helps us initialize an indirect method solving a transfer mission between periodic Lyapunov orbits. Indeed, using the PMP, the optimal control problem is solved using Newton-like algorithms finding the zero of a shooting function. To compute a Lyapunov to Lyapunov mission, we first compute an admissible trajectory using a heteroclinic orbit between the two periodic orbits. It is then used to initialize a multip
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40

Ardatovsky, M. I., and T. G. Maximova. "Combined Method of Release Planning in Agile Teams Based on Genetic Algorithms." Economics Law Innovaion, no. 4 (December 29, 2024): 60–68. https://doi.org/10.17586/2713-1874-2024-4-60-68.

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The paper analyzes the practices of release planning and task allocation in agile project management using multi-criteria optimization methods and genetic algorithms. A combined method that solves the problem of selecting re-quirements for release (Next Release Problem) based on NSGA-II algorithm and optimization of task scheduling con-sidering resource constraints and sequence of stages (Resource Constrained Project Scheduling Problem) is developed. The peculiarities of using DEAP library in Python to implement evolutionary computations are described, as well as the use of NumPy library to ac
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41

Trindade, Ana C. V., Sónia I. G. Fangaia, Pedro M. G. Nicolau, et al. "Transport Properties of Carbohydrates: Towards the Minimization Toxicological Risks of Cobalt and Chromium Ions." Processes 11, no. 6 (2023): 1701. http://dx.doi.org/10.3390/pr11061701.

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The influence of oligosaccharides (α-cyclodextrin, β-cyclodextrin and γ-cyclodextrin), and a polysaccharide, sodium hyaluronate (NaHy), on the diffusion of aqueous solutions of cobalt and chromium chlorides has been investigated. Cobalt and chromium are constituents of metal alloys for biomedical use, including dental prostheses. Thus, the release of these ions in the human body can lead to harmful biological effects. The interaction of metal ions with saccharides might have information on the role of mouthwashes in preventing these effects. This interaction has been assessed by measuring mult
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42

Jia, Zhao-Hong, Ting-Ting Wen, Joseph Y.-T. Leung, and Kai Li. "Effective heuristics for makespan minimization in parallel batch machines with non-identical capacities and job release times." Journal of Industrial & Management Optimization 13, no. 2 (2017): 977–93. http://dx.doi.org/10.3934/jimo.2016057.

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43

Vlachou, Marilena, Angeliki Siamidi, and Yannis Dotsikas. "Utilization of a Single Experimental Design for the Optimization of Furosemide Modified-Release Tablet Formulations." Current Drug Delivery 16, no. 10 (2019): 931–39. http://dx.doi.org/10.2174/1567201816666191029130324.

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Background: The loop diuretic drug furosemide is widely used for the treatment of edema in various conditions, such as pulmonary, cardiac and hepatic edema, as well as cardiac infarction. Furosemide, due to its poor water solubility and low bioavailability after oral administration of conventional dosage form, is categorized as class IV in the biopharmaceutical classification system. Objective: In the case of furosemide, this release profile is responsible for various physiological problems, acute diuresis being the most serious. This adverse effect can be circumvented by the modified release
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Trummler, T., A. Begemann, E. Trautner, and M. Klein. "Numerical investigation of the segregation of turbulent emulsions." Physics of Fluids 34, no. 11 (2022): 113324. http://dx.doi.org/10.1063/5.0112565.

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We study the segregation of emulsions in decaying turbulence using direct numerical simulations in combination with the volume of fluid method. To this end, we generate emulsions in forced homogeneous isotropic turbulence and then turn the forcing off and activate the gravitational acceleration. This allows us to study the segregation process in decaying turbulence and under gravity. We consider non-iso-density emulsions, where the dispersed phase is the lighter one. The segregation process is driven by both the minimization of the potential energy achieved by the sinking of the heavier phase
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45

Zyryanov, S. K., and I. N. Dyakov. "Updated pharmacoeconomic analysis of atesolizumab efficiency compared with other PD-1 inhibitors in patients with advanced non-small cell lung cancer after chemotherapy." FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology 16, no. 3 (2023): 422–30. http://dx.doi.org/10.17749/2070-4909/farmakoekonomika.2023.211.

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Objective: to evaluate the pharmacoeconomic efficiency of atezolizumab (inhibitor of programmed death ligand 1 (PD-L1)) in comparison with other checkpoint inhibitors (inhibitors of programmed cell death protein 1 (PD-1)) in patients with advanced non-small cell lung cancer (NSCLC) after previous chemotherapy in the current conditions of the Russian healthcare system.Material and methods. The study design was a retrospective analysis of publications and modeling. The previously performed pharmacoeconomic study was updated considering a decrease in the cost of pembrolizumab after the generic fo
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46

Marozsán, Marianna. "Examination of the possible role of biofertilizers and wood ash in the nutrient supply of plants." Acta Agraria Debreceniensis, no. 36 (November 2, 2009): 87–95. http://dx.doi.org/10.34101/actaagrar/36/2797.

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Some physiological effects of bacteria containing fertilizer and some wood ash were examined in the experiments. The minimization of the use of chemicals in agriculture has been an ongoing challenge. One option lies in the intenzification of soil life. The release of organic matters by the roots and bacteria play a significant role in the uptake of minerals. The main problem to usilize wood ash in agriculture is its heavy metal contents. The solubility of heavy metals is very low, therefore there is no risk to use the wood ash in the agriculture and in the horticulture according to our experim
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Marianna Marozsán. "The special questions of nutrition of forest plants." Acta Agraria Debreceniensis, no. 41 (December 15, 2010): 83–88. http://dx.doi.org/10.34101/actaagrar/41/2685.

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Some physiological effects of bacteria containing fertilizer and some wood ash were examined in the experiments. The minimization of the use of chemicals in agriculture has been an ongoing challenge. One option lies in the intenzification of soil life. The release of organic matters by the roots and bacteria play a significant role in the uptake of minerals. The main problem to usilize wood ash in agriculture is its heavy metal contents. Thesolubility of heavy metals is very low, therefore there is no risk to use the wood ash in the agriculture and in the horticulture according to our experime
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48

Chen, Yarong, Zailin Guan, Chen Wang, Fuh-Der Chou, and Lei Yue. "Bi-objective optimization of identical parallel machine scheduling with flexible maintenance and job release times." International Journal of Industrial Engineering Computations 13, no. 4 (2022): 457–676. http://dx.doi.org/10.5267/j.ijiec.2022.8.003.

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This paper investigates an identical parallel machine scheduling problem with flexible maintenance and job release times and attempts to optimize two objectives: the minimization of the makespan and total tardiness simultaneously. A mixed-integer programming (MIP) model for solving small-scale instances is presented first, and then a modified NSGA-Ⅱ (M-NSGA-Ⅱ) algorithm is constructed for solving medium- and large-scale instances by incorporating several strategies. These strategies include: (ⅰ) the proposal of a decoding method based on dynamic programming, (ⅱ) the design of dynamic probabili
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49

Bhowmick, Aditi, Tushar Saha, James Regun Karmoker, and Md Selim Reza. "Design of Experiment (DoE) Approach to Prepare, Characterize and Optimize the Gastroretentive Mucoadhesive Microspheres of Repaglinide." Bangladesh Pharmaceutical Journal 22, no. 2 (2019): 135–45. http://dx.doi.org/10.3329/bpj.v22i2.42297.

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In this present investigation, gastroretentive mucoadhesive microspheres of Repaglinide was formulated, characterized and optimized by applying the design of experiment (DoE) for better release profile and sustain action of the drug. Solvent evaporation technique was used to prepare microspheres, where Methocel K15M CR (X1), Eudragit L 100 (X2) and rpm (X3) were used as independent variables whereas percent cumulative drug release at 8 hours (Y1), bond strength (Y2) and swelling at 8 hours (Y3) were used as dependent variables. Particle size, surface morphology, mucoadhesive bond strength, swe
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Belyaev, A. F., and G. E. Piskunova. "Comparative analysis of changes of bioelectrical activity of the brain during the neutral touch and during the performance of the myofascial release technique." Russian Osteopathic Journal, no. 1-2 (August 8, 2018): 46–55. http://dx.doi.org/10.32885/2220-0975-2018-1-2-46-55.

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Introduction. One of the main tools of an osteopath are soft tissue techniques, which have a number of particular qualities such as minimization of force and duration of indirect techniques with an emphasis on muscle and ligamentous structures; combination of gestures, tendency to maximal relaxation and exclusion of direct action on pathological symptoms such as tension, overtone and pain. Minimization of the force applied during the performance of soft tissue techniques often invites a question whether there are differences between the usual touch and the therapeutic touch of an osteopath.Goa
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