Thematische Bibliographien / Multidrug nanoparticles

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Auswahl der wissenschaftlichen Literatur zum Thema „Multidrug nanoparticles“

Autor: Grafiati

Veröffentlicht am 29. März 2025

Zuletzt aktualisiert am 31. Juli 2025

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Zeitschriftenartikel zum Thema "Multidrug nanoparticles"

T K, Pavan, Niranjan Raj S, and Syed Baker. "Nanoparticles as Antimicrobial Agents: A Promising Solution Against Multidrug Resistance." Nanoscale Reports 8, no. 2 (2025): 5–8. https://doi.org/10.26524/nr.8.5.

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Multidrug-resistant (MDR) pathogens pose a significant threat to global health, rendering many conventional antibiotics ineffective and leading to prolonged infections, higher mortality rates, and increased healthcare costs. As resistance mechanisms continue to evolve, alternative approaches are urgently needed. Nanoparticles (NPs), due to their unique physicochemical properties, have emerged as a promising solution to combat MDR infections. This paper explores the potential of nanoparticles as antimicrobial agents, focusing on their mechanisms of action, types, and applications in fighting ba

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& MAHMOOD, HAMID. "THE SYNERGISTIC EFFECT OF GOLD NANOPARTICLE LOADED WITH CEFTAZIDIUM ANTIBIOTIC AGAINST MULTIDRUG ERSISTANCE PSEUDOMONAS AERUGINOSA." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 52, no. 4 (2021): 828–35. http://dx.doi.org/10.36103/ijas.v52i4.1391.

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This study was aimed to evaluate the antimicrobial activity of gold nanoparticles that was synthesized by biological method using Aloe Vera extract. The Surface morphology of the synthesized gold nanoparticles was confirmed by Atomic force microscope (AFM) while the nature of functional groups present in gold nanoparticles was determined by FT-IR analysis. The antibacterial activity of gold nanoparticle was tested against multidrug resistance (MDR)pseudomonas aeruginosa, the results showed a significant effect against MDR isolates. Gold nanoparticle was loaded with ceftazidium antibiotic in or

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Huq, Md Amdadul, Md Ashrafudoulla, Md Anowar Khasru Parvez, et al. "Chitosan-Coated Polymeric Silver and Gold Nanoparticles: Biosynthesis, Characterization and Potential Antibacterial Applications: A Review." Polymers 14, no. 23 (2022): 5302. http://dx.doi.org/10.3390/polym14235302.

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Biosynthesized metal nanoparticles, especially silver and gold nanoparticles, and their conjugates with biopolymers have immense potential in various fields of science due to their enormous applications, including biomedical applications. Polymeric nanoparticles are particles of small sizes from 1 nm to 1000 nm. Among different polymeric nanoparticles, chitosan-coated silver and gold nanoparticles have gained significant interest from researchers due to their various biomedical applications, such as anti-cancer, antibacterial, antiviral, antifungal, anti-inflammatory technologies, as well as t

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Abd. Alaameri, Sally K., Huda S. A. Al-Hayanni, and Labeeb A. K. Al-Zubaidi. "Antibacterial and anti-biofilm properties of biosynthesized Silver nanoparticles using Sumac (Rhus coriaria L.) extracts against some pathogenic bacteria." Sumer 3 8, CSS 3 (2023): 1–15. http://dx.doi.org/10.21931/rb/css/2023.08.03.53.

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Multidrug-resistant bacteria have contributed to a rise in morbidity and death from microbial infections, making it more difficult to treat illnesses caused by resistant pathogenic bacteria. There is a growing interest in using nanoparticles as biomaterials around the globe. Nanoparticles might become a crucial, feasible therapeutic alternative for treating infections resistant to several drugs. Currently, they are recognized as feasible alternatives or additions to conventional antimicrobials. Nanotechnology focuses on developing eco-friendly methods for producing nanoparticles. The current w

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Shair Mohammad, Imran, Birendra Chaurasiya, Xuan Yang, Chuchu Lin, Hehui Rong, and Wei He. "Homotype-Targeted Biogenic Nanoparticles to Kill Multidrug-Resistant Cancer Cells." Pharmaceutics 12, no. 10 (2020): 950. http://dx.doi.org/10.3390/pharmaceutics12100950.

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“Off-targeting” and receptor density expressed at the target sites always compromise the efficacy of the nanoparticle-based drug delivery systems. In this study, we isolated different cell membranes and constructed cell membrane-cloaked biogenic nanoparticles for co-delivery of antitumor paclitaxel (PTX) and multidrug resistance (MDR)-modulator disulfiram (DSF). Consequently, MDR cancer cell membrane (A549/T)-coated hybrid nanoparticles (A549/T CM-HNPs) selectively recognized the source cells and increased the uptake by ninefold via the homotypic binding mechanism. Moreover, the A549/T CM-HNPs

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Roszczenko, Piotr, Olga Klaudia Szewczyk, Robert Czarnomysy, Krzysztof Bielawski, and Anna Bielawska. "Biosynthesized Gold, Silver, Palladium, Platinum, Copper, and Other Transition Metal Nanoparticles." Pharmaceutics 14, no. 11 (2022): 2286. http://dx.doi.org/10.3390/pharmaceutics14112286.

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Nanomedicine is a potential provider of novel therapeutic and diagnostic routes of treatment. Considering the development of multidrug resistance in pathogenic bacteria and the commonness of cancer, novel approaches are being sought for the safe and efficient synthesis of new nanoparticles, which have multifaceted applications in medicine. Unfortunately, the chemical synthesis of nanoparticles raises justified environmental concerns. A significant problem in their widespread use is also the toxicity of compounds that maintain nanoparticle stability, which significantly limits their clinical us

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Shrivastava, A., RK Singh, PK Tyagi, and D. Gore. "Synthesis of Zinc Oxide, Titanium Dioxide and Magnesium Dioxide Nanoparticles and Their Prospective in Pharmaceutical and Biotechnological Applications." Journal of Biomedical Research & Environmental Sciences 2, no. 1 (2021): 011–20. http://dx.doi.org/10.37871/jbres1180.

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The use of nanoparticles for the therapeutic purpose is gaining pronounced importance. In the last two decades, a number of nanomedicines received regulatory approval and several showed promises through clinical trials. In this content, it is important to synthesize nanoparticles from various sources and to check its efficiency, especially its antibacterial activity. In today’s scenario number nanomedicines are proving useful to control multidrug resistance and since the mechanism of action of nanoparticles is totally different from the small molecules like antibiotics it obviates the chances

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Abhinav, Shrivastava1 Ravi Kant Singh1 Pankaj Kumar Tyagi2* and Dilip Gore3. "Synthesis of Zinc Oxide, Titanium Dioxide and Magnesium Dioxide Nanoparticles and Their Prospective in Pharmaceutical and Biotechnological Applications." Journal of Biomedical Research & Environmental Sciences 2, no. 1 (2021): 011–20. https://doi.org/10.37871/jbres1180.

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Zaineb, Tayyaba, Bushra Uzair, Waleed Y. Rizg, et al. "Synthesis and Characterization of Calcium Alginate-Based Microspheres Entrapped with TiO2 Nanoparticles and Cinnamon Essential Oil Targeting Clinical Staphylococcus aureus." Pharmaceutics 14, no. 12 (2022): 2764. http://dx.doi.org/10.3390/pharmaceutics14122764.

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It is important to create new generations of materials that can destroy multidrug-resistant bacterial strains, which are a serious public health concern. This study focused on the biosynthesis of an essential oil entrapped in titanium dioxide (TiO2) calcium alginate-based microspheres. In this research, calcium alginate-based microspheres with entrapped TiO2 nanoparticles and cinnamon essential oil (CI-TiO2-MSs) were synthesized, using an aqueous extract of Nigella sativa seeds for TiO2 nanoparticle preparation, and the ionotropic gelation method for microsphere preparation. The microspheres o

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Abdelhamid, Mohamed A. A., Mi-Ran Ki, Amer Ali Abd Abd El-Hafeez, Ryeo Gang Son, and Seung Pil Pack. "Tailored Functionalized Protein Nanocarriers for Cancer Therapy: Recent Developments and Prospects." Pharmaceutics 15, no. 1 (2023): 168. http://dx.doi.org/10.3390/pharmaceutics15010168.

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Recently, the potential use of nanoparticles for the targeted delivery of therapeutic and diagnostic agents has garnered increased interest. Several nanoparticle drug delivery systems have been developed for cancer treatment. Typically, protein-based nanocarriers offer several advantages, including biodegradability and biocompatibility. Using genetic engineering or chemical conjugation approaches, well-known naturally occurring protein nanoparticles can be further prepared, engineered, and functionalized in their self-assembly to meet the demands of clinical production efficiency. Accordingly,

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Dissertationen zum Thema "Multidrug nanoparticles"

Trần, Natalie Lan Linh. "Innovative multidrug nanomedicines for the treatment of myocardial ischemia/ reperfusion injuries." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASQ073.

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L'ischémie/ reperfusion cardiaque est une condition pathologique complexe impliquant divers mécanismes de signalisation. En raison de leurs interactions, les traitements disponibles pour les lésions de reperfusion sont souvent insuffisants. Il est donc crucial d'explorer des approches intégrantes plusieurs agents ciblant différentes voies biologiques. Bien que la nanomédecine offre des opportunités pour protéger les principes actifs et optimiser le ciblage thérapeutique, elle fait face à des défis tels qu'un faible taux d'incorporation des médicaments. La méthode de squalenoylisation pourrait

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Vlerken, Lilian Emilia van. "Modulation of multidrug resistance in cancer using polymer-blend nanoparticles : thesis /." Diss., View dissertation online, 2008. http://hdl.handle.net/2047/d10017355.

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Taute, C. J. F. "Tumour specific targeted in vitro theranostics application of fabricated nanostructures in a multi-drug resistant ovarian carcinoma cell line." Thesis, University of the Western Cape, 2013. http://hdl.handle.net/11394/4530.

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Philosophiae Doctor - PhD Ovarian cancer is called the “Silent Killer” as it is often diagnosed in advanced stages of the disease or misdiagnosed which ends with a poor prognostic outcome for the patient. A high rate of disease relapse, a high incidence-to-mortality ratio as well as acquired multidrug resistance makes it necessary to find alternative diagnostic- and therapeutic tools for ovarian cancer. Nanotechnology describes molecular devices with at least one dimension in the sub- 1μm scale and has been suggested as a possible solution for overcoming challenges in cancer multidrug resis

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Sen, Gulseren Petek. "Fabrication Of Poly (dl-lactic-co-glycolic Acid) Nanoparticles And Synthetic Peptide Drug Conjugate For Anti-cancer Drug Delivery." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12611405/index.pdf.

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Cancer is a group of diseases in which normal cells are converted to cells capable of autonomous growth and invasion. In the chemotherapeutic control of cancer, drugs are usually given systemically so they reach toxic levels in healthy cells as well as cancer cells. This causes serious side effects. Another important problem with chemotherapy is resistance developed to cytotoxic drugs (multi drug resistance). Doxorubicin (Dox) occupies a central position in the treatment of breast cancer. However doxorubicin induced cardiac toxicity is associated with a high incidence of morbidity and mortali

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Wan, Chung Ping Leon. "The effect of P-glycoprotein inhibition and ultrasound exposure on the cytotoxicity of taxane loaded diblock copolymer nanoparticles in multidrug resistant cells." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/49957.

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One of the major mechanisms of multidrug resistance involves an efflux protein, P-glycoprotein (Pgp), which pumps commonly used anticancer drugs such as taxanes out of cells, leading to a decrease in cellular drug accumulation. The overall goal of this project was to develop strategies to enhance intracellular drug accumulation and cytotoxicity of nanoparticulate taxanes in multi-drug resistant (MDR) cell lines. Paclitaxel (PTX) loaded nanoparticles fabricated from micelle forming MePEG₁₁₄-b-PCL₁₉ and nanosphere forming MePEG₁₁₄-b-PCL₁₀₄ were compared for drug and block copolymer uptake, and c

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Ngema, Xolani Terrance. "Metallic nanoparticles with polymeric shell: A multifunctional platform for application to biosensor." University of the Western Cape, 2018. http://hdl.handle.net/11394/6330.

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Philosophiae Doctor - PhD (Chemistry) Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis (MTB) that usually affects the lungs leading to severe coughing, fever and chest pains. It was estimated that over 9.6 million people worldwide developed TB and 1.5 million died from the infectious disease of which 12 % were co-infected with human immunodeficiency virus (HIV) in the year 2015. In 2016 the statistics increased to a total of 1.7 million people reportedly died from TB with an estimated 10.4 million new cases of TB diagnosed worldwide. The development of the effic

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Dormont, Flavio. "Development of nanomedicines for inflammation disorders : evaluation of pharmacological efficacy on preclinical models Nanomedicines for the management of Sepsis Nanoplumbers: Biomaterials to fight cardiovascular diseases Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation Translation of Nanomedicines from Lab to Industrial Scale Synthesis: The Case of Squalene-Adenosine Nanoparticles." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS451.

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Les syndromes inflammatoires, marqués par une réaction excessive du système immunitaire, sont associés à de nombreuses conditions pathologiques comme le sepsis, les accidents d’ischémie/reperfusion ou l’athérosclérose. En effet, une réponse inflammatoire excessive à l’encontre des tissus caractérise souvent l’apparition et la pathophysiologie de ces maladies complexes pour lesquelles ils manquent toujours des traitements efficaces. Ainsi, la plupart des thérapies disponibles pour adapter la réponse inflammatoire sont limitées la plupart du temps par des effets secondaires indésirables, une mau

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Carrasco, Letícia Dias de Melo. "Arrranjos supramoleculares de lípide catiônico, antibióticos e polímeros: preparação, caracterização e atividade contra bactérias multirresistentes e micobactérias de crescimento rápido." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-04082016-092804/.

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Arranjos supramoleculares combinando o lípide catiônico brometo de dioctadecildimetilamônio (DOD) com polímeros, como carboximetilcelulose (CMC) e cloreto de poli(dialildimetilamônio) (PDDA), foram preparados na forma de nanopartículas (NPs), na ausência ou presença de antimicrobiano tradicional, como a claritromicina (CLA). NPs preparadas por atração eletrostática entre os fragmentos de bicamada (BF) de DOD, CMC e PDDA foram avaliadas, in vitro, quanto à atividade contra isolados clínicos de micro-organismos multirresistentes (MR) a antimicrobianos, como Pseudomonas aeruginosa MR, Klebsiella

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Dreaden, Erik Christopher. "Chemistry, photophysics, and biomedical applications of gold nanotechnologies." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/51320.

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Gold nanoparticles exhibit a combination of physical, chemical, optical, and electronic properties unique from all other nanotechnologies. These structures can provide a highly multifunctional platform with which to diagnose and treat diseases and can dramatically enhance a variety of photonic and electronic processes and devices. The work herein highlights some newly emerging applications of these phenomena as they relate to the targeted diagnosis and treatment of cancer, improved charge carrier generation in photovoltaic device materials, and strategies for enhanced spectrochemical analysis

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Hsiao, Jui-Pin, and 蕭睿彬. "Development of nanoparticles with chemotherapeutic/siRNA dual functions against multidrug-resistant cancer cells." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/20319311035879470789.

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碩士 臺灣大學 醫學工程學研究所 98 To realize gene therapy and chemotherapy in multi-drug-resistant cancer cell, we develop carriers which can co-delivery gene and chemotherapy drug. The mPEG-PCL-PEI (M510i) tri-block polymers were synthesized by use mMPEG-PCL copolymer modified to PEI. The characteristic of these tri-block polymers were evaluated by 1H nuclear magnetic resonance and gel permeation chromatography. The critical micelle concentration (CMC) of micelle was evaluated by using pyrene as fluorescence probe. The particle size, zeta potential, and morphology of micelle was studied by dyna

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Bücher zum Thema "Multidrug nanoparticles"

Banu, Afreen, Vandana Rathod, and E. Ranganath. Synthesis and Characterization of Silver Nanoparticles by Rhizopus Stolonifer and Its Activity Against Multidrug Resistant Escherichia Coli and S. GRIN Verlag GmbH, 2012.

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Wong, Ho-Lun. A study of nanoparticle drug carrier for treatment of multidrug-resistant breast cancer with loco-regional involvement. 2006.

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Buchteile zum Thema "Multidrug nanoparticles"

Palaskar, Rutuja S., Darshana S. Dhokane, and Balaprasad G. Ankamwar. "Green-Synthesized Nanoparticles to Combat Multidrug-Resistant Bacteria." In Nanotechnology Based Strategies for Combating Antimicrobial Resistance. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-2023-1_19.

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Chandrasekaran, Aiswarya, and G. H. R. Eranga Karunaratne. "Use of Nanoparticles in Multidrug Resistant Tuberculosis Diagnosis." In Nanotechnology for Infectious Diseases. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9190-4_17.

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Hossain, Md Monir, Shakil Ahmed Polash, Tanushree Saha, and Satya Ranjan Sarker. "Gold Nanoparticles: A Lethal Nanoweapon Against Multidrug-Resistant Bacteria." In Nanotechnology in the Life Sciences. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-10220-2_9.

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Uddin, Imran, Divya S. Parimi, Tarun K. Bollu, Chandra S. Bhatt, and Anil K. Suresh. "Silver Nanoparticles as Potent Multidrug-Resistant Incorporants in Biomedicine." In Emerging Modalities in Mitigation of Antimicrobial Resistance. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84126-3_21.

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Tian, Sichao, Peiyan Yuan, and Qing-Hua Xu. "Metal Nanoparticles As Alternative Antimicrobial Agents to Combat Multidrug Resistance Bacteria." In Nanotechnology Based Strategies for Combating Antimicrobial Resistance. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-2023-1_4.

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Bharadwaj, Kaushik Kumar, Bijuli Rabha, Bhabesh Kumar Choudhury, et al. "Role of Gold Nanoparticles Against Multidrug Resistance (MDR) Bacteria: An Emerging Therapeutic Revolution." In Emerging Modalities in Mitigation of Antimicrobial Resistance. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84126-3_22.

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Ahmed, Abeer Ahmed Qaed, Lin Xiao, Tracey Jill Morton McKay, and Guang Yang. "Green Metal-Based Nanoparticles Synthesized Using Medicinal Plants and Plant Phytochemicals against Multidrug-Resistant Staphylococcus aureus." In Green Synthesis in Nanomedicine and Human Health. CRC Press, 2021. http://dx.doi.org/10.1201/9781003023197-15.

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Parmar, Ankush, and Shweta Sharma. "Nanoparticles: A Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections—A Holistic View on Underlying Mechanisms and Antibacterial Properties." In Biomedical Translational Research. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9232-1_11.

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Bondhopadhyay, Banashree, Tanmay J. Urs, Shreya Gupta, and Ruchika Ruchika. "Nano-Engineered Therapies for Breast Cancer." In Innovations and Applications of Advanced Biomaterials in Healthcare and Engineering. IGI Global, 2025. https://doi.org/10.4018/979-8-3373-1305-4.ch012.

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The effectiveness of the conventional treatment strategies is falling, as tumors are gradually becoming chemoresistant. Breast cancer cells are persistently overexposed to therapeutic agents, leading them to develop multidrug resistance. Molecular mechanisms causing Multidrug Resistance (MDR) include the overexpression of drug efflux transporters, evasion of apoptosis, activation of NF-κB and other signaling pathways supporting tumor proliferation, dysregulation of DNA repair mechanisms, epigenetic modulations and tumor-supportive microenvironment. This present study explores the biomedical ap

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Pinky, Nirantak Kumar, and Ankita Sharma. "Synergic Effects of Nanoparticles with other Drugs and Their Combined Effects." In Plant Mediated Synthesis of Metal Nanoparticles. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815256352124010007.

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As discussed in previous chapters that the formation of nanoparticles results in various advantages for multidrug delivery when combined with particular drug as compared to free drugs. So this article emphasize on use of nanoparticle and drug combination to reduce the toxicity and improve the efficiency which is given in the form of advantages. Drud combination analysis has been explained in the form of isoboles and dose equivalent etc. Synergic effects of drug-nanoparticle combination on bacteria, fungi, virus, diabetes and cancer has been shown by proper mechanism. Beside these harmful effec

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Konferenzberichte zum Thema "Multidrug nanoparticles"

Sabir, Dana. "SYNERGISTIC EFFECT OF SILVER NANOPARTICLES COMBINED WITH DIFFERENT ANTIBIOTICS AGAINST MULTIDRUG-RESISTANT ACINETOBACTER BAUMANNII STRAIN H72721." In International Conference of Natural Science. Presidency of Charmo University, 2018. http://dx.doi.org/10.31530/17028.

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Yuvasree, P., K. Nithya, and N. Neelakandeswari. "Biosynthesis of silver nanoparticles from Aloe vera plant extract and its antimicrobial activity against multidrug resistant pathogens." In International Conference on Advanced Nanomaterials & Emerging Engineering Technologies (ICANMEET-2013). IEEE, 2013. http://dx.doi.org/10.1109/icanmeet.2013.6609241.

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Wang, Xu, Jun Li, Yuxiang Wang, et al. "Abstract LB-196: A folate receptor-targeted nanoparticle minimizes multidrug resistance in human cancer xenograft model." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-196.

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