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Zeitschriftenartikel zum Thema „Nap optimization“

Autor: Grafiati

Veröffentlicht am 28. Juli 2024

Zuletzt aktualisiert am 31. Juli 2025

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1

Huaccallo-Aguilar, Ysabel, Silvia Álvarez-Torrellas, Marcos Larriba, et al. "Optimization Parameters, Kinetics and Mechanism of Naproxen Removal by Catalytic Wet Peroxide Oxidation with a Hybrid Iron-Based Magnetic Catalyst." Catalysts 9, no. 3 (2019): 287. http://dx.doi.org/10.3390/catal9030287.

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This work presents a study of the assessment of the operating parameters of the catalytic wet peroxide oxidation (CWPO) of naproxen (NAP) using magnetite/multi-walled carbon nanotubes (Fe3O4/MWCNTs) as a catalyst. The effect of pH, temperature, and H2O2 dosage on CWPO process was evaluated by using the response surface model (RSM), allowing us to obtain an optimum NAP removal of 82% at the following operating conditions: pH = 5, T = 70 °C, [H2O2]0 = 1.5 mM, and [NAP]0 = 10.0 mg/L. Therefore, NAP degradation kinetics were revealed to follow a pseudo-second-order kinetic model, and an activation

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Noreen, Sobia, Fahad Pervaiz, Akram Ashames, et al. "Optimization of Novel Naproxen-Loaded Chitosan/Carrageenan Nanocarrier-Based Gel for Topical Delivery: Ex Vivo, Histopathological, and In Vivo Evaluation." Pharmaceuticals 14, no. 6 (2021): 557. http://dx.doi.org/10.3390/ph14060557.

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Naproxen (NAP) is commonly used for pain, inflammation, and stiffness associated with arthritis. However, systemic administration is linked with several gastrointestinal tract (GIT) side effects. The present work aims to prepare and evaluate NAP nanoparticulate shells of chitosan (CS) and carrageenan (CRG) loaded into a Carbopol 940 (Ca-940) gel system with unique features of sustained drug delivery as well as improved permeation through a topical route. Moreover, this study aims to evaluate its ex vivo, histopathological, and in vivo anti-inflammatory activity in albino Wistar rats. The perce

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Huaccallo-Aguilar, Ysabel, Silvia Álvarez-Torrellas, Johanny Martínez-Nieves, et al. "Magnetite-Based Catalyst in the Catalytic Wet Peroxide Oxidation for Different Aqueous Matrices Spiked with Naproxen–Diclofenac Mixture." Catalysts 11, no. 4 (2021): 514. http://dx.doi.org/10.3390/catal11040514.

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Magnetite supported on multiwalled carbon nanotubes catalysts were synthesized by co-precipitation and hydrothermal treatment. The magnetic catalysts were characterized by X-ray diffraction, Fourier-transform infrared spectrometry, thermogravimetric analysis and N2 physisorption. The catalysts were then tested for their ability to remove diclofenac (DCF) and naproxen (NAP) from an aqueous solution at different conditions (pH, temperature, and hydrogen peroxide) to determine the optimum conditions for chemical oxidation. The optimization of the process parameters was conducted using response su

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Sipeky, Csilla, and Béla Melegh. "Haplogroup analysis of vitamin-K epoxide reductase (VKORC1) gene: novel element in the optimization of anticoagulant therapy." Orvosi Hetilap 149, no. 39 (2008): 1839–44. http://dx.doi.org/10.1556/oh.2008.28456.

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A warfarin és az acenokumarolok a leggyakrabban alkalmazott antikoagulánsok, amelyek szűk terápiás tartománnyal rendelkeznek, a hatásos dózis pedig populáción belül és egyénenként is nagy változatosságot mutat. A kumarinok a K-vitamin-epoxidreduktáz enzim (VKOR) gátlásán keresztül akadályozzák meg a koagulációt. Az enzimet kódoló VKORC1 gén mutációi jelentősen befolyásolják a kumarinok iránti érzékenységet. A VKORC1 gén genetikai variabilitását a *2, *3 és a *4 haplotípusok fedik le a kaukázusi populációban. Antikoaguláns kezelésben részesülő betegek bemutatásán keresztül összefoglaló tanulmán

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Kobayashi, Ryo. "nap: A molecular dynamics package with parameter-optimization programs for classical and machine-learning potentials." Journal of Open Source Software 6, no. 57 (2021): 2768. http://dx.doi.org/10.21105/joss.02768.

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Thetford, Jay, Melisa Chang, and Kevin Eng. "1156 “NIV Nap” to Improve PAP Acceptability and Hypoventilation in Neuromuscular Disease." SLEEP 47, Supplement_1 (2024): A495. http://dx.doi.org/10.1093/sleep/zsae067.01156.

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Abstract Introduction Respiratory failure is the most common cause of death in patients with several types of neuromuscular disease (NMD), including myotonic dystrophy type 1 (MD1). Non-invasive ventilation (NIV) is the cornerstone of treatment, but consistent use and acceptability remain a challenge. While nap-titrations have improved CPAP adherence in obstructive sleep apnea (OSA), we present a case where increased use and optimization of therapy was achieved through a daytime nap NIV titration. Report of case(s) 47-year-old man with MD1, obesity , and mild OSA with long-standing PAP intoler

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Darwish, Hany W., Ahmed H. Bakheit, and Ali S. Abdelhameed. "Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods." Acta Pharmaceutica 66, no. 1 (2016): 83–95. http://dx.doi.org/10.1515/acph-2016-0004.

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Abstract Simultaneous spectrophotometric analysis of a multi-component dosage form of olmesartan, amlodipine and hydrochlorothiazide used for the treatment of hypertension has been carried out using various chemometric methods. Multivariate calibration methods include classical least squares (CLS) executed by net analyte processing (NAP-CLS), orthogonal signal correction (OSC-CLS) and direct orthogonal signal correction (DOSC-CLS) in addition to multivariate curve resolution-alternating least squares (MCR-ALS). Results demonstrated the efficiency of the proposed methods as quantitative tools o

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McCormick, Frank, John Kadzielski, Brady T. Evans, Christopher P. Landrigan, James Herndon, and Harry Rubash. "Fatigue Optimization Scheduling in Graduate Medical Education: Reducing Fatigue and Improving Patient Safety." Journal of Graduate Medical Education 5, no. 1 (2013): 107–11. http://dx.doi.org/10.4300/jgme-d-12-00021.1.

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Abstract Background Medical error is a major cause of preventable morbidity and mortality. Resident fatigue is likely to be a significant contributor. Objectives We calculated and compared predicted fatigue impairment in surgical residents on varying schedules by using the validated Sleep, Activity, Fatigue, and Task Effectiveness model and Fatigue Avoidance Scheduling Tool; we identified specific times of day and rotations during which residents were most affected, instituted countermeasures, and measured the predicted response. Methods We compared 4 scheduling patterns: day shift, trauma shi

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Чернявская, С. А., С. А. Мартиросян та С. С. Шевченко. "Тенденции и перспективы развития налога на профессиональный доход в России". Applied Economic Researches Journal, № 3 (27 травня 2025): 35–42. https://doi.org/10.47576/2949-1908.2025.3.3.004.

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Налог на профессиональный доход (НПД) стал важным элементом налоговой политики России, способствуя легализации деятельности самозанятых граждан и упрощению налогообложения для малого бизнеса. НПД значительно упростил процессы регистрации и уплаты налогов, что сделало его привлекательным для широкого круга индивидуальных предпринимателей. С каждым годом наблюдается рост числа зарегистрированных самозанятых, что подтверждает эффективность и актуальность налогового режима. В статье рассматриваются динамика численности самозанятых, изменения в структурах налоговых поступлений, а также миграционные

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Larsen, Trine Schifter, and Mari Holen. "Sleep as Homework and Engagement in Rehabilitation." Anthropology & Aging 42, no. 2 (2021): 105–25. http://dx.doi.org/10.5195/aa.2021.284.

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In today’s push for shorter and quicker hospitalisations, everyday life often becomes a place of rehabilitation for people after they undergo surgical procedures. In order for hospitals to manage shortened periods of admission and to facilitate post-operative rehabilitation, a patient‘s active engagement has become a central element to clinical treatment and care in Denmark. For example, in the recovery from orthopedic surgery, sleep becomes a type of "homework" assignment that is a vital element of the patient‘s rehabilitation trajectory. Building on the theoretical concept of ‘engagement’ de

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Srinivas, Subadhra, and K. Prabakaran. "A novel approach for solving the triangular fuzzy neutrosophic assignment problem." Yugoslav Journal of Operations Research, no. 00 (2024): 25. http://dx.doi.org/10.2298/yjor240316025s.

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The assignment problem (AP) is a fundamental challenge in linear programming and operations research focused on optimizing assignments to minimize costs or maximize profits. This study extends the traditional AP to address uncertainties and ambiguities through the neutrosophic assignment problem (NAP). Further advancing this concept, the triangular fuzzy neutrosophic assignment problem (TFNAP) is introduced, utilizing triangular fuzzy neutrosophic numbers (TFNNs) to represent fuzziness and neutrosophy, thus offering a more comprehensive depiction of uncertainty and indeterminacy. The primary a

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Afanaseva, Olesya, Viktor El'mov, and Svetlana Filippova. "Comparing the Performance of dairy farming by households and self-employed people based on a project business model." Agrarian Bulletin of the 231, no. 02 (2023): 83–97. http://dx.doi.org/10.32417/1997-4868-2023-231-02-83-97.

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Abstract. The purpose. The level of marketability of milk in the households of the population of some subjects of the Volga Federal District from 2011 to 2021 increased by more than 20 p. p. The leader in this rating was the Chuvash Republic with the marketability of milk in the households of the population in 2021 at the level of 77.5 %. In connection with the high involvement of the population in the organized market for the sale of milk, the authors developed an economic and mathematical model for calculating the level of efficiency of dairy cattle breeding in the households of the populati

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Wu, C., J. Valenta, E. Hamilton, K. Modrow, and W. N. Osburn. "The Optimization of the Concentrations of Sodium Lactate (Nal), Sodium Erythorbate (Nae), and Sodium Bicarbonate (Nab) Applied to Beef Trimmings for Ground Beef Production." Meat and Muscle Biology 3, no. 2 (2019): 51. http://dx.doi.org/10.22175/mmb2019.0051.

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Aghera, Payal. "Enhanced Production of Citric Acid by Mutant PN12 of Aspergillus fumigatus Using Statistical Design." Bioscience Biotechnology Research Communications 14, no. 4 (2021): 1473–79. http://dx.doi.org/10.21786/bbrc/14.4.16.

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Distillery spent wash is an unwanted residual liquid waste generated during alcohol production. It is a potential source for production of different industrially important products. Distillery spent wash is dark colored and has many organic compounds as a waste. In this experiment, removal of color and organic compounds was carried out by anaerobic treatment. The treated spent wash was utilized for citric acid production with the help of microorganisms. The current study was performed with the treated spent wash which was applied for high level of citric acid production by a mutant strain of A

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Wibowo, Enggar, Raul Garcia-Diez, Tomas Bystron, et al. "Oxidation of Aqueous H₃PO₃ on Pt Studied By X-Ray Spectroscopies." ECS Meeting Abstracts MA2022-02, no. 56 (2022): 2162. http://dx.doi.org/10.1149/ma2022-02562162mtgabs.

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High-temperature polymer electrolyte membrane fuel cells (HT-PEMFCs) employing a phosphoric acid H3PO4-doped membrane are considered to be promising sustainable electrochemical energy storage. The high-temperature operation has several advantages, such as a higher tolerance to CO poisoning, allowing coupling of HT-PEMFCs with reformers [1-3], as well the possibility for heat and electric energy co-generation [1,2]. However, during operation, phosphorus oxo-acids (e.g.: H3PO3) are generated on the anode. These impurities adsorb on the Pt catalyst [4-6], thus possibly negatively affecting the HT

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Jiang, Zhihua, John Kamerud, Minlei Zhang, et al. "Strategies to develop highly drug-tolerant cell-based neutralizing antibody assay: neutralizing antidrug antibodies extraction and drug depletion." Bioanalysis 12, no. 18 (2020): 1279–93. http://dx.doi.org/10.4155/bio-2020-0091.

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Aim: Drug interference poses great analytical challenges for cell-based neutralizing antidrug antibodies (NAb) assay. The work aimed to improve assay drug tolerance through biotin-drug extraction with acid dissociation method optimization and developing new approach. Results: The NAb extraction with biotin-drug extraction with acid dissociation approach has been optimized by reducing biotinylated drug leaching and improving NAb elution efficiency, resulting in drug tolerance of up to 160 μg/ml. To circumvent the low acid elution efficiency of NAb from drug, a novel drug depletion approach was

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Szi Hui, Tan, and Mohamad Khairi Ishak. "Spike neuron optimization using deep reinforcement learning." IAES International Journal of Artificial Intelligence (IJ-AI) 10, no. 1 (2021): 175. http://dx.doi.org/10.11591/ijai.v10.i1.pp175-183.

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Deep reinforcement learning (DRL) which involved reinforcement learning and artificial neural network allows agents to take the best possible actions to achieve goals. Spiking Neural Network (SNN) faced difficulty in training due to the non-differentiable spike function of spike neuron. In order to overcome the difficulty, Deep Q network (DQN) and Deep Q learning with normalized advantage function (NAF) are proposed to interact with a custom environment. DQN is applied for discrete action space whereas NAF is implemented for continuous action space. The model is trained and tested to validate

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Tan, Szi Hui, and Khairi Ishak Mohamad. "Spike neuron optimization using deep reinforcement learning." International Journal of Artificial Intelligence (IJ-AI) 10, no. 1 (2021): 175–83. https://doi.org/10.11591/ijai.v10.i1.pp175-183.

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Deep reinforcement learning (DRL) which involved reinforcement learning and artificial neural network allows agents to take the best possible actions to achieve goals. Spiking neural network (SNN) faced difficulty in training due to the non-differentiable spike function of spike neuron. In order to overcome the difficulty, deep Q network (DQN) and deep Q learning with normalized advantage function (NAF) are proposed to interact with a custom environment. DQN is applied for discrete action space whereas NAF is implemented for continuous action space. The model is trained and tested to validate

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Prabhanjan, Shinde, and Desai Sandeep. "EMISSION OPTIMIZATION OF 60 HP AGRICULTURAL TRACTOR ENGINE." JournalNX - A Multidisciplinary Peer Reviewed Journal RIT PG Con-18 (April 22, 2018): 22–24. https://doi.org/10.5281/zenodo.1413138.

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In order to meet emission norms, modern diesel engines rely on methods of in-cylinder emission reduction and expensive exhaust after treatment devices. Engine manufacturers across the world are finding difficulty in maintaining balance between customers demand for better fuel consumption and obeying the stringent legislative emission regulations. The main goal of this experimental work is to investigate the effect of optimum combination of variables such as piston bowl diameter with the range of increase up to 1-2 mm precisely matched with engine. Then, the experimental tests were carried out

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Kamboj, Harsimran, Krishan Kumar, J. S. Brar, Anil Kumar, and Parshotam Kumar (PK) Arora. "Optimization of in vitro propagation of jamun variety Konkan Bahadoli." Indian Journal of Horticulture 80, no. 03 (2023): 245–50. http://dx.doi.org/10.58993/ijh/2023.80.3.3.

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Micro-propagation is a vital technique for round-the-year clonal multiplication of plants. Jamun is anindigenous fruit tree with great pharmacological importance. Two explants viz., shoot tips and nodal explants were cultured from January to May. The shoot regeneration from nodal explants was tested using 6-benzyl amino purine (BAP; 1.0-4.0 mg l-1) and α-naphthalene acetic acid (NAA; 0-0.25 mg l-1), while rooting was investigated with NAA (0.5-2.0 mg l-1). Maximum explant establishment was recorded in May. The nodal explants showed better establishment response (50.0%) than shoot tips (40.7%).

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Wong, Wai Tuck, Sarah Kinsey, Ramesha Karunasena, Thanh H. Nguyen, and Arunesh Sinha. "Beyond NaN: Resiliency of Optimization Layers in the Face of Infeasibility." Proceedings of the AAAI Conference on Artificial Intelligence 37, no. 12 (2023): 15242–50. http://dx.doi.org/10.1609/aaai.v37i12.26778.

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Prior work has successfully incorporated optimization layers as the last layer in neural networks for various problems, thereby allowing joint learning and planning in one neural network forward pass. In this work, we identify a weakness in such a set-up where inputs to the optimization layer lead to undefined output of the neural network. Such undefined decision outputs can lead to possible catastrophic outcomes in critical real time applications. We show that an adversary can cause such failures by forcing rank deficiency on the matrix fed to the optimization layer which results in the optim

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Li, Hui Jun, Daniel Grudgings, Nathan Larkin, John Norrish, Mark Callaghan, and Lenka Kuzmikova. "Optimization of Welding Parameters for Repairing NiAl Bronze Components." Materials Science Forum 706-709 (January 2012): 2980–85. http://dx.doi.org/10.4028/www.scientific.net/msf.706-709.2980.

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The objective of this study is to determine an optimal welding procedure that can be implemented to repair damaged Nickel Aluminium Bronze (NAB) components. NAB is commonly used in marine applications where components are subject to a constant corrosive environment and high stresses. Research into ideal NAB microstructure for a marine application, was performed in order to gain a baseline for experimental analysis of potential welding procedures. The results indicated that the welding repair can be performed with a wide range of heat input. The effect of post-weld heat treatment (PWHT) on the

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Wadapurkar, Rucha, Swarda Deo, Renuka Khanzode, and Ajay Singh. "Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products." Pharmaceutics 17, no. 1 (2024): 30. https://doi.org/10.3390/pharmaceutics17010030.

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Background/Objectives: The nucleic acid-based product (NAP) portfolio is expanding continuously and provides safer curative options for many disease indications. Nucleic acid-based products offer several advantages compared to proteins and virus-based products. They represent an emerging field; thus, their quality control and regulatory landscape is evolving to ensure adequate quality and safety. Next-Generation Sequencing (NGS) is mostly recommended for NAP identity testing, and we are leveraging its application for impurity profiling. Methods: We proposed a workflow for the purity assessment

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Sandow, Lyndsey, Justin Grenet, Adel Kardosh, et al. "NeoOPTIMIZE: Phase II trial of adaptive switching of neoadjuvant FOLFIRINOX (FFX) to gemcitabine/nab-paclitaxel (GA) resectable/borderline resectable (BR)/locally advanced (LA) pancreatic adenocarcinoma (PDAC)." Journal of Clinical Oncology 43, no. 16_suppl (2025): 4190. https://doi.org/10.1200/jco.2025.43.16_suppl.4190.

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4190 Background: Neoadjuvant chemotherapy (NAC) for localized PDAC may improve R0 resection. FFX and GA are used but lack of predictive biomarkers remains a barrier to optimal NAC. The angiotensin-II receptor blocker (ARB), losartan, remodels vascular perfusion to enhance NAC efficacy. We established an experimental platform for dynamic switching of NAC +/- radiation therapy for resectable/BR PDAC and an exploratory cohort of LA PDAC. Methods: Patients (pts) received 4 cycles of FFX (ox 85 mg/m2; LV 400 mg/m2; iri 150 mg/m2; 5-FU 2400 mg/m2), then were restaged in a multi-disciplinary tumor bo

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Bernabei, R., and A. Incicchitti. "Low background techniques in NaI(Tl) setups." International Journal of Modern Physics A 32, no. 30 (2017): 1743007. http://dx.doi.org/10.1142/s0217751x17430072.

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The application of very low background techniques is fundamental in deep underground experiments dedicated to the investigation of rare processes. In this paper, the case of NaI(Tl) detectors is discussed mainly considering their crucial role for direct Dark Matter (DM) investigation. In particular, the DAMA/LIBRA apparatus, as a result of a long-standing activity focused on the optimization of NaI(Tl) detectors, is underlined.

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Demeler, Borries, and Guangwen Zhou. "Neural network optimization forE.colipromoter prediction." Nucleic Acids Research 19, no. 7 (1991): 1593–99. http://dx.doi.org/10.1093/nar/19.7.1593.

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Royset, Johannes O., and Hiroyuki Sato. "Route optimization for multiple searchers." Naval Research Logistics (NRL) 57, no. 8 (2010): 701–17. http://dx.doi.org/10.1002/nav.20432.

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Gunduz, Seval, Dhruba J. Deka, Jaesung Kim, Serra Yesilata, and Umit Ozkan. "High-Temperature Electrocatalysis in Electrolyzer and Ion-Pump Modes: Insights from Operando Spectroscopy and Microscopy." ECS Meeting Abstracts MA2025-01, no. 52 (2025): 2600. https://doi.org/10.1149/ma2025-01522600mtgabs.

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High-temperature electrocatalysis plays a crucial role in advancing energy conversion processes, i.e. chemicals to electricity conversion (fuel cell mode) and electricity to chemicals conversion (electrolyzer and ion-pump modes) with high efficiency. Despite the significant progress in the development of these processes, a deeper understanding of the structural dynamics of electrode materials under the electrochemical reaction conditions and the relation between the structural changes and the activity/selectivity/stability of these electrodes remain a key challenge due to the complex nature of

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Nazarov, V. M., M. V. Frontasyeva, P. A. Lavdanskij, and N. I. Stephanov. "NAA for optimization of radiation shielding of nuclear power plants." Journal of Radioanalytical and Nuclear Chemistry Articles 180, no. 1 (1994): 83–95. http://dx.doi.org/10.1007/bf02039906.

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Kamal, N., KM Nasuruddin, MS Haque, and S. Yasmin. "Optimization of Regeneration Protocol of Rice from Embryo Derived Callus." Progressive Agriculture 18, no. 2 (2013): 25–33. http://dx.doi.org/10.3329/pa.v18i2.17461.

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An efficient and reproducible protocol for in vitro regeneration is required to achieve high frequency transformation from transformed calli. We report here high frequency plant regeneration from mature embryonic calli of two BINA rice cultivars Binasail and Binadhan-4. Embryonic calllus initiated on MS basal medium supplemented with 2 mg/l 2, 4-D. Several media with different combinations of growth regulators were tried. Maximum shoot regeneration frequency (63.33%) was observed in Binadhan-4 on MS medium supplemented with 5 mg/l Kinetin + 0.5 mg/l NAA. Maximum root regeneration frequency (70

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Levitin, G. "Threshold optimization for weighted voting classifiers." Naval Research Logistics 50, no. 4 (2003): 322–44. http://dx.doi.org/10.1002/nav.10061.

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Wang, Yin, and Ruiling Yao. "Optimization of rhizogenesis for in vitro shoot culture of Pinus massoniana Lamb." Journal of Forestry Research 32, no. 1 (2019): 203–9. http://dx.doi.org/10.1007/s11676-019-01076-8.

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AbstractThe rooting capacity of Pinusmassoniana is poor, especially for mature trees, and has prevented the development of clonal forestry for P.massoniana. In this study, we varied explant types, subculture times and exogenous hormones for plantlet regeneration and assessed shoots for rooting rate and root number for P.massoniana. Following five repetitive grafts, new shoots from grafts used as explant sources were rejuvenated as observed from juvenile shoot morphology and anatomy, leading to greatly enhanced plant regeneration in comparison to that of mature materials from 26-year-old P.mass

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Wang, Qian, Boyan Cai, Yajie Yu, and Hui Cao. "Spectral Quantitative Analysis Model with Combining Wavelength Selection and Topology Structure Optimization." Journal of Spectroscopy 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/5616503.

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Spectroscopy is an efficient and widely used quantitative analysis method. In this paper, a spectral quantitative analysis model with combining wavelength selection and topology structure optimization is proposed. For the proposed method, backpropagation neural network is adopted for building the component prediction model, and the simultaneousness optimization of the wavelength selection and the topology structure of neural network is realized by nonlinear adaptive evolutionary programming (NAEP). The hybrid chromosome in binary scheme of NAEP has three parts. The first part represents the to

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Gingas, V. M., J. C. Kamalay, and S. C. Domir. "041 OPTIMIZATION OF ULMUS SUSPENSION CULTURES FOR ELICITOR/PHYTOALEXIN EXPERIMENTS." HortScience 29, no. 5 (1994): 433f—433. http://dx.doi.org/10.21273/hortsci.29.5.433f.

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Suspension cultures of five elm selections (U. americana A, 680, 8630 and Del 2 and U. pumila S) exhibiting a range of susceptibility responses to the Dutch Elm Disease fungus (Ophiostoma ulmi) have been successfully established for future elicitor/phytoalexin studies. Calli initiated from foliar tissues of mature, greenhouse-grown trees cultured on a solid modified MS medium containing 2,4-D and BA were adapted to a liquid modified MS medium containing BA and either IAA or NAA. Cells were grown in either the presence or absence of light with continuous agitation. Uniform, rapidly dividing cel

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Hum, Sin‐Hoon, and Mahmut Parlar. "Modeling and optimization of multilevel marketing operations." Naval Research Logistics (NRL) 69, no. 4 (2021): 581–98. http://dx.doi.org/10.1002/nav.22031.

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Chuang, Li-Yeh, Jui-Hung Tsai, and Cheng-Hong Yang. "Binary particle swarm optimization for operon prediction." Nucleic Acids Research 38, no. 12 (2010): e128-e128. http://dx.doi.org/10.1093/nar/gkq204.

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Andradóttir, Sigrún, and Andrei A. Prudius. "Adaptive random search for continuous simulation optimization." Naval Research Logistics (NRL) 57, no. 6 (2010): 583–604. http://dx.doi.org/10.1002/nav.20422.

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Gandomi, A. H., A. R. Kashani, M. Mousavi, and M. Jalalvandi. "Slope stability analysis using evolutionary optimization techniques." International Journal for Numerical and Analytical Methods in Geomechanics 41, no. 2 (2016): 251–64. http://dx.doi.org/10.1002/nag.2554.

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Diković, Jasmina, and Ida Panev. "SQLquery tuning and optimization." Zbornik Veleučilišta u Rijeci 11, no. 1 (2023): 289–310. http://dx.doi.org/10.31784/zvr.11.1.16.

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Količina nastalih informacija svakim se danom povećava, a time rastu i zahtjevi za kapacitetomračunalnih resursa kojima se one obrađuju i analiziraju. Rastuću ulogu u obradi podataka imaračunarstvo u oblaku. Budući da se korištenje usluga u oblaku uobičajeno temelji na plaćanju popotrošnji, poznavanjem mogućnosti optimizacije i efikasnog korištenja resursa moguće je upravljatiželjenim performansama i troškovima. U ovom radu opisani su i prikazani na praktičnom primjerurazličiti postupci koji se mogu provesti u svrhu optimizacije podataka i SQL upita, a prilikom korištenjausluga u oblaku za rad

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Matteucci, Federica, Marta Ferrati, Eleonora Spinozzi, et al. "Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes." Pharmaceuticals 17, no. 6 (2024): 739. http://dx.doi.org/10.3390/ph17060739.

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Nicotinamide adenine dinucleotide (NAD) cofactor metabolism plays a significant role in cancer development. Tumor cells have an increased demand for NAD and ATP to support rapid growth and proliferation. Limiting the amount of available NAD by targeting critical NAD biosynthesis enzymes has emerged as a promising anticancer therapeutic approach. In mammals, the enzyme nicotinamide/nicotinic acid adenylyltransferase (NMNAT) catalyzes a crucial downstream reaction for all known NAD synthesis routes. Novel nicotinamide/nicotinic acid adenine dinucleotide (NAD/NaAD) analogues 1–4, containing a met

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George, Jacob, Harsh Pal Bais, G. A. Ravishankar, and P. Manilal. "Optimization of Media Constituents for Shoot Regeneration from Leaf Callus Cultures of Decalepis hamiltonii Wight. & Arn." HortScience 35, no. 2 (2000): 296–99. http://dx.doi.org/10.21273/hortsci.35.2.296.

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Response surface methodology was utilized in statistical optimization of three quality factors (the number of multiple shoots, shoot length, and number of leaves) pertaining to regeneration of plantlets from leaf calli of Decalepis hamiltonii Wight. & Arn. (swallow root). The variables evaluated were the levels of sucrose, BA, and NAA each at two different concentrations. Response surfaces for shoot length and multiple shoot number were useful in achieving optimal levels of media constituents and in understanding their interactions, but response surfaces for number of leaves were not. The

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LIPMAN, JUSTIN, PAUL BOUSTEAD, and JOHN JUDGE. "NEIGHBOR AWARE ADAPTIVE POWER FLOODING (NAAP) IN MOBILE AD HOC NETWORKS." International Journal of Foundations of Computer Science 14, no. 02 (2003): 237–52. http://dx.doi.org/10.1142/s0129054103001704.

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This paper introduces Neighbor Aware Adaptive Power flooding, an optimized flooding mechanism used in mobile ad hoc networks (MANETS) that employs several mechanisms (neighbor coverage, power control, neighbor awareness and local optimization) to limit the broadcast storm problem, reduce duplicate packet reception and lower power consumption in both transmission and reception. Upon receiving an optimized broadcast, a relay determines a new set of possible relays (to continue the flood) based upon local neighbor information and the previous optimized broadcast. Additionally, neighboring relays

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F. B歡kmann, Andreas. "Optimization of the Synthesis of N(1)-(2-Aminoethyl)-NAD(P)." HETEROCYCLES 27, no. 7 (1988): 1623. http://dx.doi.org/10.3987/com-87-4475.

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Rusičová, Zuzana, and Magdaléna Bálintová. "Environmental Risk Assessment for Landscape - ecological Planning in the City Vranov nad Topľou." Selected Scientific Papers - Journal of Civil Engineering 7, no. 2 (2012): 41–50. http://dx.doi.org/10.2478/v10299-012-0005-2.

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Abstract Pollution of the environment components in many cases presents unacceptable risks to human health and the environment. Risk analysis is one of the tools which help to find a socially acceptable level of the environmental quality. Evaluation of the environmental impacts can be the base for the optimal spatial arrangement and functional use of territory - landscape optimization. In Slovakia, LANDEP methodology based on the principles of sustainable development, is very often used for landscape planning. The paper deals with environmental risk assessment of components of environment (air

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Jafari, Marziyeh, and Mohammad Hosein Daneshvar. "Machine learning-mediated Passiflora caerulea callogenesis optimization." PLOS ONE 19, no. 1 (2024): e0292359. http://dx.doi.org/10.1371/journal.pone.0292359.

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Callogenesis is one of the most powerful biotechnological approaches for in vitro secondary metabolite production and indirect organogenesis in Passiflora caerulea. Comprehensive knowledge of callogenesis and optimized protocol can be obtained by the application of a combination of machine learning (ML) and optimization algorithms. In the present investigation, the callogenesis responses (i.e., callogenesis rate and callus fresh weight) of P. caerulea were predicted based on different types and concentrations of plant growth regulators (PGRs) (i.e., 2,4-dichlorophenoxyacetic acid (2,4-D), 6-be

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Phung, Khanh Dai, Liem Thanh Le, and Quang Trong Hoang. "Using mathematical programming method to optimize amount of injection gas for Dai Hung field, Nam Con Son basin, offshore Vietnam." Science and Technology Development Journal 17, no. 3 (2014): 166–71. http://dx.doi.org/10.32508/stdj.v17i3.1492.

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During oil – production by gaslift method, because of the limitation of injection gas rate, the optimization of distributing injection gas rate for group of well is universally interesting. There are some optimization methods for gaslift well in Vietnam, nearly all uses analytical mathematic method with solutions finding the extrema for multivariable function. This paper presents an optimization method for group of gaslift well to increase the oil rate for Dai Hung field, Nam Con Son Basin, offshore Vietnam.

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Oyama, Takahiro, Takumi Yamamoto, Takeshi Kameda, et al. "Supplementation of Nicotinic Acid and Its Derivatives Up-Regulates Cellular NAD+ Level Rather than Nicotinamide Derivatives in Cultured Normal Human Epidermal Keratinocytes." Life 14, no. 3 (2024): 413. http://dx.doi.org/10.3390/life14030413.

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Nicotinamide adenine dinucleotide (NAD+) plays a pivotal role in various physiological processes within mammalian cells, including energy metabolism, redox homeostasis, and genetic regulation. In the majority of mammalian cellular contexts, NAD+ biosynthesis primarily relies on vitamin B3, including nicotinamide (NAM) and nicotinic acid (NA). The concept of NAD+ augmentation therapy has recently emerged as a promising strategy to mitigate aging-associated phenomena, termed rejuvenation. Despite the involvement of diverse enzymatic cascades in NAD+ biosynthesis, certain cellular environments ex

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Bellut, Konstantin, Maximilian Michel, Martin Zarnkow, et al. "Screening and Application of Cyberlindnera Yeasts to Produce a Fruity, Non-Alcoholic Beer." Fermentation 5, no. 4 (2019): 103. http://dx.doi.org/10.3390/fermentation5040103.

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Non-alcoholic beer (NAB) is enjoying growing demand and popularity due to consumer lifestyle trends and improved production methods. In recent years in particular, research into the application of non-Saccharomyces yeasts to produce NAB via limited fermentation has gained momentum. Non-Saccharomyces yeasts are known to produce fruity aromas, owing to a high ester production. This trait could be harnessed to mask the often-criticized wort-like off-flavor of NAB produced via limited fermentation. Six Cyberlindnera strains were characterized and screened in wort extract. Four of the six strains p

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Welner, Ditte H., Søren Lindemose, J. Günter Grossmann, et al. "DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors." Biochemical Journal 444, no. 3 (2012): 395–404. http://dx.doi.org/10.1042/bj20111742.

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NAC (NAM/ATAF/CUC) plant transcription factors regulate essential processes in development, stress responses and nutrient distribution in important crop and model plants (rice, Populus, Arabidopsis), which makes them highly relevant in the context of crop optimization and bioenergy production. The structure of the DNA-binding NAC domain of ANAC019 has previously been determined by X-ray crystallography, revealing a dimeric and predominantly β-fold structure, but the mode of binding to cognate DNA has remained elusive. In the present study, information from low resolution X-ray structures and s

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Trunjaruen, Attachai, Prathan Luecha, and Worasitikulya Taratima. "The Optimization of Medium Conditions and Auxins in the Induction of Adventitious Roots of Pokeweed (Phytolacca americana L.) and Their Phytochemical Constituents." Scientifica 2023 (August 21, 2023): 1–14. http://dx.doi.org/10.1155/2023/2983812.

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Pokeweed, Phytolacca americana L., is considered a widely spreading invasive plant, while saponin contents accumulated in the roots have pharmaceutical uses, such as rheumatism treatments and anti-inflammation. Adventitious root cultures are an important source of diverse secondary metabolites, which have significant applications in various fields. This study focused on the optimization of parameters for root induction using different medium states and treatments with auxins on a pokeweed leaf. Semisolid and liquid MS (Murashige and Skoog, 1962) media were supplemented with indole-3-butyric ac

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