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1

Pushpanjali., A. Bidwai, N. Wankhade Lokesh, and S. Bhonde Rajkumar. "Responses of the neurosecretory cells of the terrestrial slug, Semperula maculata to temperature acclimation (32°c and 15°c." Int. Res. Journal of Science & Engineering, 2023 A13 (December 31, 2023): 29–33. https://doi.org/10.5281/zenodo.10516175.

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Changes in the neurosecretory cell (cell A and cell B) cytology of <em>Semperula maculata </em>subjected to thermal acclimation (32&deg;c <u>+</u> 0.5&deg;c and 15&deg;c <u>+</u> 0.5&deg;c) for 10 days have been investigated. Of the two temperatures in which slugs are acclimated striking changes were evident in 32&deg;c than 15&deg;c. After acclimation treatment (15&deg;c) there was increase in neurosecretory material and nuclear diameter in cell A and cell B. While on 32&deg;c acclimation, nuclear diameter of the slug showed enlargement and neurosecretory material intensity was lowered in cel
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2

Mrdakovic, Marija, Larisa Ilijin, Milena Jankovic-Tomanic, et al. "Effects of thermal stress on activity of corpora allata and dorsolateral neurosecretory neurons in Morimus funereus larvae." Archives of Biological Sciences 57, no. 2 (2005): 83–92. http://dx.doi.org/10.2298/abs0502083m.

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The effects of different temperatures (23?C and 8?C) on activity of corpora allata (CA) and dorsolateral (L1, L2) protocerebral neurosecretory neurons were investigated in Morimus funereus Mulsant (1863) larvae collected from a natural population during March. Activity of CA was revealed by monitoring of CA volume and cell number. Increase of CA volume after two day exposure to both temperatures was shown to be the result of increase in cell number. Activity of CA was higher at 23?C than 8?C. Activity of L1 and L2 neurosecretory neurons was inhibited at both temperatures. Neurosecretory neuron
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3

Raghavan, Sudha Devi Arath, Aswani Ayanath, and Bhadravathi Kenchappa Chandrasekhar Sagar. "Fine structure of neurosecretory cells and sinus gland in the eyestalk of the freshwater crab Travancoriana schirnerae Bott, 1969 (Decapoda: Gecarcinucidae)." Brazilian Journal of Biological Sciences 6, no. 14 (2019): 535–55. http://dx.doi.org/10.21472/bjbs.061406.

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This study elucidated the fine structure of neurosecretory cells and sinus gland in the optic ganglia of the freshwater crab Travancoriana schirnerae Bott, 1969 (Decapoda: Gecarcinucidae). The eyestalk ganglion showed the presence of four well defined ganglia arranged below the ommatidium: lamina ganglionaris, medulla externa, medulla interna and medulla terminalis of which the lamina ganglionaris, was devoid of neurosecretory cells. Groups of neurosecretory cells seen distributed along the medulla externa, interna and terminalis regions constitute the X-organs. Electron microscopic observatio
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4

Rossler, W., and U. Bickmeyer. "LOCUST MEDIAL NEUROSECRETORY CELLS IN VITRO: MORPHOLOGY, ELECTROPHYSIOLOGICAL PROPERTIES AND EFFECTS OF TEMPERATURE." Journal of Experimental Biology 183, no. 1 (1993): 323–39. http://dx.doi.org/10.1242/jeb.183.1.323.

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The medial neurosecretory cells of the pars intercerebralis in the protocerebrum of larval and adult locusts (Locusta migratoria) were cultured in a chemically defined serum-free culture medium. The morphology of the cells was investigated by light microscopy and the electrophysiological properties were studied using the patch-clamp technique in the whole-cell configuration. The dissociated neurosecretory cells grew new processes under these conditions and were maintained in culture for up to 2 months. The percentage of cells showing outgrowth was significantly higher in third-instar larvae th
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5

Mahmud, S., PV Mladenov, SC Chakraborty, and MAR Faruk. "Relationship Between Gonad Condition and Neurosecretory Cell Activity in the Green-Lipped Mussel, Perna canaliculus." Progressive Agriculture 18, no. 2 (2014): 135–48. http://dx.doi.org/10.3329/pa.v18i2.18169.

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The relationship between the activity of neurosecretory cells and gonad development of Perna canaliculus was investigated. The variation in staining intensity of the neurosecretory cells in different ganglia was evaluated. Changes in staining intensity of neurosecretory cells (NSC) were correlated with gonad development. The variation in colour intensity (CI) resulted from differences in the amount of secretory materials within the NSCs. The neurosecretory cell types A and B showed a similar pattern of staining intensity, and showed correlation with gametogenesis and spawning. At the beginning
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6

Meyer, C., M. J. Freund-Mercier, Y. Guerné, and Ph Richard. "Relationship between oxytocin release and amplitude of oxytocin cell neurosecretory bursts during suckling in the rat." Journal of Endocrinology 114, no. 2 (1987): 263–70. http://dx.doi.org/10.1677/joe.0.1140263.

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ABSTRACT Plasma concentrations of oxytocin and vasopressin were measured in relationship to oxytocin cell firing during suckling in urethane-anaesthetized rats. Preliminary experiments showed that plasma concentrations of oxytocin and vasopressin, which were increased immediately after anaesthesia, reverted to basal concentrations 3 h later. Moreover, it was found that exogenous oxytocin had entirely disappeared 5 min after i.v. bolus injections of known doses of oxytocin. Suckling did not modify the basal plasma concentration of oxytocin (14·6 ± 2·9 compared with 14·±61·5 pmol/l before suckli
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7

Fairweather, I., and D. W. Halton. "Neuropeptides in platyhelminths." Parasitology 102, S1 (1991): S77—S92. http://dx.doi.org/10.1017/s0031182000073315.

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The neuropeptide story began in 1928 with the description by Ernst Scharrer of gland-like nerve cells in the hypothalamus of the minnow, Phoxinus laevis. Because these nerve cells were overwhelmingly specialized for secretory activity, overshadowing other neuronal properties, Scharrer termed them ‘neurosecretory neurons’. What was even more remarkable about the cells was that their products were released into the bloodstream to act as hormones, specifically neurohormones. Neurosecretory cells were identified largely on morphological grounds. That is, they could be stained with special techniqu
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8

Göhde, Ronja, Benjamin Naumann, Davis Laundon, et al. "Choanoflagellates and the ancestry of neurosecretory vesicles." Philosophical Transactions of the Royal Society B: Biological Sciences 376, no. 1821 (2021): 20190759. http://dx.doi.org/10.1098/rstb.2019.0759.

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Neurosecretory vesicles are highly specialized trafficking organelles that store neurotransmitters that are released at presynaptic nerve endings and are, therefore, important for animal cell–cell signalling. Despite considerable anatomical and functional diversity of neurons in animals, the protein composition of neurosecretory vesicles in bilaterians appears to be similar. This similarity points towards a common evolutionary origin. Moreover, many putative homologues of key neurosecretory vesicle proteins predate the origin of the first neurons, and some even the origin of the first animals.
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9

Shamsiyeva, N. К., and A. A. Khusinov. "Activities of the anterior hypothalamus neurosecretory nuclear enzymes in exposure to organophosphorus compounds." Problems of Endocrinology 39, no. 2 (1993): 49–51. http://dx.doi.org/10.14341/probl11977.

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Under study were activities of glycolysis enzymes: LDH, Crebs cycle SDH, those of electron transport system NAD and NADP-diaphorase, and of the hydrolytic enzymes, acid and alkaline phosphatases in the hypothalamus, as were morphofunctional shifts in these enzymes activities in poisoning with organophosphorus compounds. The experiments were carried out in 72 white male outbread rats weighing 180-200 g, that were administered PHOS antio (an organophosphorus compound) in a daily dose of 0.1 LD50 for 30 days. Early dates of poisoning were associated with an essential rise of the redox enzymes and
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10

Garcia, U., and H. Arechiga. "Regulatory Influences on Crustacean Neurosecretory Cells." Physiology 12, no. 1 (1997): 16–21. http://dx.doi.org/10.1152/physiologyonline.1997.12.1.16.

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During the last decade, new evidence has been produced on the subtle mechanisms by which invertebrate neurosecretory cell activity is regulated. Multiple synaptic and humoral mechanisms regulate the endogenous activity of secretory neurons. Specific cellular interactions and ionic mechanisms have been disclosed, and new insights are now available on the integrative features of invertebrate neurosecretory systems.
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11

ICHIKAWA, TOSHIO. "Architecture of Cerebral Neurosecretory Cell Systems in the Silkworm Bombyx Mori." Journal of Experimental Biology 161, no. 1 (1991): 217–37. http://dx.doi.org/10.1242/jeb.161.1.217.

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Anatomical and physiological characteristics of putative neurosecretory cells (NSCs) in the medial and lateral areas of the larval brain of Bombyx mori, identifiable by the opalescent appearance of their somata, were examined by means of intracellular recording and staining. Intracellular injection of Lucifer Yellow revealed that the medial cell group consisted of at least six subgroups of cells distinguishable by the geometry of their dendritic branches. Five subgroups of cells project axons to the contralateral corpus allatum (CA) or to the corpus cardiacum (CC). The remaining subgroup sends
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12

Brown, Colin H., John A. Russell, and Gareth Leng. "Opioid modulation of magnocellular neurosecretory cell activity." Neuroscience Research 36, no. 2 (2000): 97–120. http://dx.doi.org/10.1016/s0168-0102(99)00121-2.

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13

Navone, F., G. Di Gioia, R. Jahn, M. Browning, P. Greengard, and P. De Camilli. "Microvesicles of the neurohypophysis are biochemically related to small synaptic vesicles of presynaptic nerve terminals." Journal of Cell Biology 109, no. 6 (1989): 3425–33. http://dx.doi.org/10.1083/jcb.109.6.3425.

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Nerve endings of the posterior pituitary are densely populated by dense-core neurosecretory granules which are the storage sites for peptide neurohormones. In addition, they contain numerous clear microvesicles which are the same size as small synaptic vesicles of typical presynaptic nerve terminals. Several of the major proteins of small synaptic vesicles of presynaptic nerve terminals are present at high concentration in the posterior pituitary. We have now investigated the subcellular localization of such proteins. By immunogold electron microscopy carried out on bovine neurohypophysis we h
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14

Wen, Peter J., Shona L. Osborne, Isabel C. Morrow, Robert G. Parton, Jan Domin та Frederic A. Meunier. "Ca2+-regulated Pool of Phosphatidylinositol-3-phosphate Produced by Phosphatidylinositol 3-Kinase C2α on Neurosecretory Vesicles". Molecular Biology of the Cell 19, № 12 (2008): 5593–603. http://dx.doi.org/10.1091/mbc.e08-06-0595.

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Phosphatidylinositol-3-phosphate [PtdIns(3)P] is a key player in early endosomal trafficking and is mainly produced by class III phosphatidylinositol 3-kinase (PI3K). In neurosecretory cells, class II PI3K-C2α and its lipid product PtdIns(3)P have recently been shown to play a critical role during neuroexocytosis, suggesting that two distinct pools of PtdIns(3)P might coexist in these cells. However, the precise characterization of this additional pool of PtdIns(3)P remains to be established. Using a selective PtdIns(3)P probe, we have identified a novel PtdIns(3)P-positive pool localized on s
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15

Bai, Hongdong, Samir Nangia, and Robert J. Parmer. "The Plasminogen Activation System and the Regulation of Catecholaminergic Function." Journal of Biomedicine and Biotechnology 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/721657.

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The local environment of neurosecretory cells contains the major components of the plasminogen activation system, including the plasminogen activators, tissue plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), as well as binding sites for t-PA, the receptor for u-PA (uPAR), and also the plasminogen activator inhibitor, PAI-1. Furthermore, these cells express specific binding sites for plasminogen, which is available in the circulation and in interstitial fluid. Colocalization of plasminogen and its activators on cell surfaces provides a mechanism for promoting local
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16

Onetti, C. G., U. Garcia, R. F. Valdiosera, and H. Arechiga. "Ionic currents in crustacean neurosecretory cells." Journal of Neurophysiology 64, no. 5 (1990): 1514–26. http://dx.doi.org/10.1152/jn.1990.64.5.1514.

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1. The patterns of electrical activity and membrane characteristics of a population of neurosecretory-cell somata in the X-organ of the crayfish were investigated with microelectrodes and whole-cell, voltage-clamp techniques. Some neurons (56%) were silent but could be excited by intracellular current injection: other cells showed spontaneous tonic activity (35%), and some had spontaneous bursting activity (9%). The spiking activity was abolished by tetrodotoxin (TTX) exposure and by severing the axon near the cell body. After axotomy, only a small, slow, regenerative depolarization remained t
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17

Day, T. A., and J. R. Sibbald. "Noxious somatic stimuli excite neurosecretory vasopressin cells via A1 cell group." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 258, no. 6 (1990): R1516—R1520. http://dx.doi.org/10.1152/ajpregu.1990.258.6.r1516.

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Activation of nociceptive somatic afferents excites hypothalamic neurosecretory cells and stimulates the release of vasopressin. To investigate the possibility that relevant afferent information is relayed through the A1 norepinephrine cell group of the caudal ventrolateral medulla, single-unit recording experiments were performed in pentobarbital sodium-anesthetized rats. The effects of somatic nerve stimulation, application of noxious somatic stimuli, and A1 region stimulation on the activity of putative vasopressin-secreting neurosecretory cells of the supraoptic nucleus were compared. The
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18

Fuenzalida, Lidia C., Kim L. Keen, and Ei Terasawa. "Colocalization of FM1-43, Bassoon, and GnRH-1: GnRH-1 Release from Cell Bodies and Their Neuroprocesses." Endocrinology 152, no. 11 (2011): 4310–21. http://dx.doi.org/10.1210/en.2011-1416.

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Pulsatile release of GnRH-1 is critical for reproductive function. However, the cellular mechanism of GnRH-1 neurosecretion is still elusive. In this study, we examined the neurosecretory process of GnRH-1 neurons using time-lapse image acquisition followed by immunocytochemistry with confocal microscopy. To monitor exocytotic processes, cultured GnRH-1 neurons derived from monkey embryos were labeled with the lipophilic dye, FM1-43, or its fixable form FM1-43Fx, in the presence or absence of depolarization signals, and changes in vesicles labeled with FM1-43 were analyzed. The results show FM
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Nässel, Dick R., and Meet Zandawala. "Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions." Cell and Tissue Research 382, no. 2 (2020): 233–66. http://dx.doi.org/10.1007/s00441-020-03264-z.

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Abstract Hormones regulate development, as well as many vital processes in the daily life of an animal. Many of these hormones are peptides that act at a higher hierarchical level in the animal with roles as organizers that globally orchestrate metabolism, physiology and behavior. Peptide hormones can act on multiple peripheral targets and simultaneously convey basal states, such as metabolic status and sleep-awake or arousal across many central neuronal circuits. Thereby, they coordinate responses to changing internal and external environments. The activity of neurosecretory cells is controll
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Latchford, Kevin J., and Alastair V. Ferguson. "Angiotensin depolarizes parvocellular neurons in paraventricular nucleus through modulation of putative nonselective cationic and potassium conductances." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 289, no. 1 (2005): R52—R58. http://dx.doi.org/10.1152/ajpregu.00549.2004.

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Neurosecretory parvocellular neurons in the hypothalamic paraventricular nucleus (PVN) exercise considerable influence over the adenohypophysis and thus play a critical role in neuroendocrine regulation. ANG II has been demonstrated to act as a neurotransmitter in PVN, exerting significant impact on neuronal excitability and also influencing corticotrophin-releasing hormone secretion from the median eminence and, therefore, release of ACTH from the pituitary. We have used whole cell patch-clamp techniques in hypothalamic slices to examine the effects of ANG II on the excitability of neurosecre
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Hatcher, Nathan G., and Jonathan V. Sweedler. "Aplysia Bag Cells Function as a Distributed Neurosecretory Network." Journal of Neurophysiology 99, no. 1 (2008): 333–43. http://dx.doi.org/10.1152/jn.00968.2007.

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The anatomical organization of many neuroendocrine systems implies multiple sites of hormone release in areas mediating multiple aspects of physiology and behavior, yet this neurosecretory complexity has not often been verified. Here we probe the well-characterized hormonal model, the reproductive bag cell neuroendocrine system of the sea slug Aplysia californica. The bag cell neurons of Aplysia mediate egg-laying behavior through the coordinated secretion of a suite of peptides derived from a single gene product, the egg-laying prohormone (proELH). Although the majority of bag cell neurons ar
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22

Biserova, N. M., I. A. Kutyrev, and V. V. Malakhov. "New type of gland discovered in cestodes: neurosecretory neurons release a secret into the fish host." Доклады Российской академии наук. Науки о жизни 514, no. 1 (2024): 16–20. http://dx.doi.org/10.31857/s2686738924010039.

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In 5 species of cestode plerocercoids parasitizing fish, free endings of peripheral neurosecretory neurons were found in the tegument in the ultrastructural study. These free terminals secreted vesicles on the tegument surface and into the host body. An increase in secretion under the influence of the blood serum of a fish host has been experimentally shown. In the body of cestodes, neurosecretory neurons (NN) form paracrine-type contacts near the cell membranes of the frontal glands, tegument, and muscles, performing the function of endocrine glands. Simultaneously, NN function as exocrine gl
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23

Ilijin, Larisa, Marija Mrdakovic, Vesna Peric-Mataruga, et al. "Adjustment of L1 neurosecretory neuron activity in response to different stressors in gypsy moth caterpillars." Archives of Biological Sciences 67, no. 3 (2015): 965–72. http://dx.doi.org/10.2298/abs141210059i.

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Gypsy moth caterpillars were exposed to an increased rearing temperature of 35?C and diet, supplemented with Cd, a heavy metal pollutant, and tannic acid, a plant secondary metabolite. After 3 days? exposure to stressors, changes in the number, morphometric parameters of L1 neurosecretory neurons (nsn) (sizes of the nsn and their nuclei), and the quantity of neurosecretory material in the cytoplasm of the neurons were estimated. Acute exposure to the high temperature of 35?C induced increases in the number of L1 nsn, their size and the size of their nuclei with prolonged exposure time. After a
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24

Quatacker, J. R., W. G. Annaert, B. J. Miserez, and W. P. De Potter. "Immunocytochemical demonstration of dopamine-beta-hydroxylase and cytochrome B561 on the axonal reticulum in bovine sympathetic neurons." Journal of Histochemistry & Cytochemistry 40, no. 10 (1992): 1599–604. http://dx.doi.org/10.1177/40.10.1527378.

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In sympathetic neurons the axonal reticulum can be considered an extension of the secretory pole of the Golgi apparatus. If this tubular system indeed represents the neurosecretory apparatus, it would likely contain on its membranes the enzymes involved in catecholamine synthesis. To test this hypothesis, we investigated the distribution of dopamine-beta-hydroxylase and cytochrome b561 in bovine splenic nerve and nerve terminals in the vas deferens with an immunogold procedure after glycolmethacrylate embedding. Counterstaining with phosphotungstic acid at low pH selectively revealed the axona
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KHAN, H., and A. SALEUDDIN. "Neurofilaments of the neurosecretory cells of a snail." Cell Biology International Reports 11, no. 10 (1987): 691–97. http://dx.doi.org/10.1016/0309-1651(87)90127-5.

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Schenk, Elaine B., Frederic A. Meunier, and Dietmar B. Oelz. "Spatial redistribution of neurosecretory vesicles upon stimulation accelerates their directed transport to the plasma membrane." PLOS ONE 17, no. 3 (2022): e0264521. http://dx.doi.org/10.1371/journal.pone.0264521.

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Through the integration of results from an imaging analysis of intracellular trafficking of labelled neurosecretory vesicles in chromaffin cells, we develop a Markov state model to describe their transport and binding kinetics. Our simulation results indicate that a spatial redistribution of neurosecretory vesicles occurs upon secretagogue stimulation leading vesicles to the plasma membrane where they undergo fusion thereby releasing adrenaline and noradrenaline. Furthermore, we find that this redistribution alone can explain the observed up-regulation of vesicle transport upon stimulation and
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Wang, X., SN Treistman, A. Wilson, JJ Nordmann, and JR Lemos. "Ca2+ Channels and Peptide Release From Neurosecretory Terminals." Physiology 8, no. 2 (1993): 64–68. http://dx.doi.org/10.1152/physiologyonline.1993.8.2.64.

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Evoked release of neuropeptides and/or neurotransmitters requires activation of membrane Ca2+ channels. Because of the generally small size and inaccessibility of nerve endings, most electrophysiological studies have observed this activation only in cell bodies. However, recent techniques have permitted insights into the diversity and behavior of Ca2+ channels in neurosecretory terminals.
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Cuzin-Roudy, Janine, and A. S. M. Saleuddin. "A study of the neurosecretory centres of the eyestalk in Siriella armata M. Edw. (Crustacea: Mysidacea): their involvement in molting and reproduction." Canadian Journal of Zoology 63, no. 12 (1985): 2783–88. http://dx.doi.org/10.1139/z85-416.

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Neurosecretory cells and centres arc described in the eyestalk of the mysid Siriela armata. The sinus gland is situated on the neuropilar regions along the main blood sinus. The medulla interna and medulla externa X organ is formed of G1 cells; the medulla terminalis X organ consists of G3 and G4 cells. Other neurons, the G2 cells, and a "giant cell" may also be neurosecretory. Destruction of the medulla interna – medulla externa X organ results in an inhibition of the preparation for molt and ecdysis in both sexes. Reproducing females also show inhibition of secondary vitellogenesis and of ma
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Mukai, S. T., and A. S. M. Saleuddin. "Mating increases the synthetic activity of the neurosecretory caudodorsal cells of Helisoma duryi (Mollusca: Pulmonata)." Canadian Journal of Zoology 67, no. 10 (1989): 2363–67. http://dx.doi.org/10.1139/z89-334.

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In Helisoma duryi, virgin snails lay significantly fewer eggs than mated snails. It is generally accepted that in basommatophoran pulmonates, the neurosecretory caudodorsal cells located in the cerebral ganglia produce a hormone that regulates egg laying. The synthetic activity of the caudodorsal cells in Helisoma has been measured in vitro and in vivo using tritiated leucine. Virgin and castrated snails (reproductively inactive) showed significantly reduced levels of [3H]leucine incorporation compared with first-mated snails (24 and 48 h postmating). This increase in synthetic activity follow
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Osborne, Shona L., Peter J. Wen, Christine Boucheron, et al. "PIKfyve Negatively Regulates Exocytosis in Neurosecretory Cells." Journal of Biological Chemistry 283, no. 5 (2007): 2804–13. http://dx.doi.org/10.1074/jbc.m704856200.

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31

Chaudhuri, P. S., and R. Datta. "Neuroendocrine control of cocoon production in native earthworm Perionyx ceylanensis subjected to seasonal variation." Journal of Environmental Biology 42, no. 4 (2021): 930–37. http://dx.doi.org/10.22438/jeb/42/4/mrn-1658.

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Aim: The aim of the present study was to observe the role of cerebral ganglionic neurosecretory cells (NSCs) during cocoon production in native earthworm species Perionyx ceylanensis subjected to amputation and seasonal variations. Methodology: Histological studies (using Aldehyde Fuchsin and Chrome Alum Haematoxylin Phloxin stain) were carried out on brain NSCs in the two groups of earthworms (Group I and Group II) maintained in earthen culture pots (2L) with cowdung as food. Group I comprised of brain amputed earthworms was subjected to observe the role of brain NSCs in production of cocoon
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Day, T. A., and J. Ciriello. "Effects of renal receptor activation on neurosecretory vasopressin cells." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 253, no. 2 (1987): R234—R241. http://dx.doi.org/10.1152/ajpregu.1987.253.2.r234.

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Electrical stimulation of afferent renal nerves (ARN) has been shown to excite neurosecretory vasopressin (AVP) cells of the supraoptic nucleus (SON). To investigate the sensory modality of the ARN involved, the present study examined in pentobarbital-anesthetized rats the responses of putative AVP cells to procedures intended to differentially activate renal receptor populations. Neurosecretory SON cells were identified by antidromic invasion from the neurohypophysis and classified as AVP secreting on the basis of spontaneous activity patterns and responses to arterial baroreceptor activation
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Senarat, Sinlapachai, Naritsara Saeluea, Ezra Mongkolchaichana, et al. "Systemic Histology of the Marine Water-Strider Halobates hayanus (Heteropera, Gerridae)." Sains Malaysiana 52, no. 9 (2023): 2485–98. http://dx.doi.org/10.17576/jsm-2023-5209-02.

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The structure and cell types of the organs of Halobates hayanus from Libong Island, Thailand, were investigated using a histological method. The integumentary system of this species consists of three layers: epicuticle, exocuticle, and endocuticle. Throughout the body, the muscular system exclusively included skeletal muscle. In the excretory system, we found four fully formed Malpighian tubules, each one lined with a straightforward cuboidal epithelium harbouring secretory granules. The digestive system comprised a foregut, midgut, and hindgut. The midgut had three distinct cell types: basal
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34

Russell, J. T., M. Levine, and D. Njus. "Electron transfer across posterior pituitary neurosecretory vesicle membranes." Journal of Biological Chemistry 260, no. 1 (1985): 226–31. http://dx.doi.org/10.1016/s0021-9258(18)89720-4.

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McBurney, R. N., and S. J. Kehl. "Electrophysiology of neurosecretory cells from the pituitary intermediate lobe." Journal of Experimental Biology 139, no. 1 (1988): 317–28. http://dx.doi.org/10.1242/jeb.139.1.317.

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One of the goals in studying the electrical properties of neurosecretory cells is to relate their electrical activity to the process of secretion. A central question in these studies concerns the role of transmembrane calcium ion flux in the initiation of the secretory event. With regard to the secretory process in pituitary cells, several research groups have addressed this question in vitro using mixed primary anterior pituitary cell cultures or clonal cell lines derived from pituitary tumours. Other workers, including ourselves, have used homogeneous cell cultures derived from the pituitary
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Knoll, Gerd, Helmut Plattner, and Jean J. Nordmann. "Exo-endocytosis in isolated peptidergic nerve terminals occurs in the sub-second range." Bioscience Reports 12, no. 6 (1992): 495–501. http://dx.doi.org/10.1007/bf01122037.

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Exo- and endocytotic processes induced by depolarization of isolated neurosecretory nerve terminals show a close temporal correlation, which suggests a short time of integration of the neurosecretory granule membrane with the plasma membrane. In order to determine minimal time requirements for exocytosis-coupled endocytosis to occur, we have analyzed by electron microscopy uptake of horserdish peroxidase (HRP) as a fluid phase marker at the onset of depolarization. We have applied rapid mixing and sampling (quenched flow) to assess events in subsecond time peroids after stimulation. A signific
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Bräunig, Peter. "Neurons without dendrites? – A novel type of neurosecretory cell in locusts." Arthropod Structure & Development 44, no. 6 (2015): 604–7. http://dx.doi.org/10.1016/j.asd.2015.06.004.

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Borgonovo, Barbara, Gabriella Racchetti, MariaLuisa Malosio, et al. "Neurosecretion Competence, an Independently Regulated Trait of the Neurosecretory Cell Phenotype." Journal of Biological Chemistry 273, no. 52 (1998): 34683–86. http://dx.doi.org/10.1074/jbc.273.52.34683.

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39

Garcia, E., A. Benitez, and C. G. Onetti. "Responsiveness to D-glucose in neurosecretory cells of crustaceans." Journal of Neurophysiology 70, no. 2 (1993): 758–64. http://dx.doi.org/10.1152/jn.1993.70.2.758.

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1. An electrophysiological study of the D-glucose sensitivity of X-organ (XO) neurosecretory cell bodies in crayfish was carried out with the use of microelectrodes, perforated, and cell-attached patch-clamp techniques. 2. Glucose depolarizes the membrane potential of XO cells in a concentration-dependent manner. 3. Depolarization produced by glucose initiates a change in the pattern of electrical activity. Silent cells began to discharge action potentials. When bursting cells are depolarized by glucose, their action potentials are no longer grouped in bursts or disappear entirely. 4. Although
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BRÄUNIG, PETER. "A Suboesophageal Ganglion Cell Innervates Heart and Retrocerebral Glandular Complex in the Locust." Journal of Experimental Biology 156, no. 1 (1991): 567–82. http://dx.doi.org/10.1242/jeb.156.1.567.

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The suboesophageal ganglion of the migratory locust Locusta migratoria contains a pair of large neurosecretory cells located posteriorly, close to the sagittal plane. By means of double labelling, it is shown that the cells are immunoreactive to bovine pancreatic polypeptide. Using a combination of electrophysiological, neuroanatomical and immunocytochemical methods, it is shown that the neurones project into the corpora cardiaca with ascending anterior axons and into the lateral cardiac nerve cords with posterior axons that descend into the thoracic and abdominal nerve cord.
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Cohen, Stewart L., Kenneth E. Miller, and Richard M. Kriebel. "Distribution of serotonin in the caudal neurosecretory complex." Anatomy and Embryology 181, no. 5 (1990): 491–98. http://dx.doi.org/10.1007/bf02433796.

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42

Biceroglu, Gulay, Teoman Akcay, Gonul Aydogan, et al. "Irradiation-Induced Growth Hormone Neurosecretory Disfunction In ALL Patients." Blood 116, no. 21 (2010): 4329. http://dx.doi.org/10.1182/blood.v116.21.4329.4329.

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Abstract Abstract 4329 With the recent developments in the treatment of ALL life expectancy is prolonged and complications due to therapy are increased. Combined chemotherapy may be applied in combination with distinct doses and schema of cranial radiotherapy according to the risk groups of patients. CRT damages the hypothalamus-hypophysis axis and affects the secretion of growth hormone (GH) at first and the other anterior hypophysis hormones also. At high doses of CRT, GH deficiency might occur in the long term follow-up, at lower doses the secretion pattern of GH may change. In this study,
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MASSE, Marie J. O., Pierette DESBOIS-PERICHON, and Paul COHEN. "Identification of Neurophysin-Related Proteins in Bovine Neurosecretory Granules." European Journal of Biochemistry 127, no. 3 (2005): 609–17. http://dx.doi.org/10.1111/j.1432-1033.1982.tb06916.x.

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44

Álvarez, Ramón Alvarado, Mercedes Graciela Porras Villalobos, Gabina Calderón Rosete, Leonardo Rodríguez Sosa, and Hugo Aréchiga. "Dopaminergic Modulation of Neurosecretory Cells in the Crayfish." Cellular and Molecular Neurobiology 25, no. 2 (2005): 345–70. http://dx.doi.org/10.1007/s10571-005-3064-9.

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45

Shanbaky, Nawal M., Ashraf El-Said, and Nadia Helmy. "Changes in Neurosecretory Cell Activity in Female Argas (Argas) hermanni (Acari: Argasidae)." Journal of Medical Entomology 27, no. 6 (1990): 975–81. http://dx.doi.org/10.1093/jmedent/27.6.975.

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46

Malosio, M. L. "Dense-core granules: a specific hallmark of the neuronal/neurosecretory cell phenotype." Journal of Cell Science 117, no. 5 (2004): 743–49. http://dx.doi.org/10.1242/jcs.00934.

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47

Ichikawa, Toshio. "Synchronous firing dynamics in a heterogeneous neurosecretory-cell population in an insect." Brain Research 929, no. 2 (2002): 156–65. http://dx.doi.org/10.1016/s0006-8993(01)03349-2.

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Chang, David Horng-Chyi, Swei Hsueh, and Yung-Kuei Soong. "Small cell carcinoma with neurosecretory granules arising in an ovarian dermoid cyst." Gynecologic Oncology 46, no. 2 (1992): 246–50. http://dx.doi.org/10.1016/0090-8258(92)90265-k.

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Akai, Hiromu, Takayuki Nagashima, Shinji Aoyagi, et al. "Development and secretory function of neurosecretory A cell in brain ofBombyx mori." Archives of Insect Biochemistry and Physiology 32, no. 3-4 (1996): 333–40. http://dx.doi.org/10.1002/(sici)1520-6327(1996)32:3/4<333::aid-arch6>3.0.co;2-t.

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50

Rowe, J., N. Corradi, M. L. Malosio, et al. "Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1." Journal of Cell Science 112, no. 12 (1999): 1865–77. http://dx.doi.org/10.1242/jcs.112.12.1865.

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The t-SNAREs syntaxin1A and SNAP-25, i.e. the members of the complex involved in regulated exocytosis at synapses and neurosecretory cells, are delivered to their physiological site, the plasma membrane, when transfected into neurosecretion-competent cells, such as PC12 and AtT20. In contrast, when transfection is made into cells incompetent for neurosecretion, such as those of a defective PC12 clone and the NRK fibroblasts, which have no endogenous expression of these t-SNAREs, syntaxin1A (but neither two other syntaxin family members nor SNAP-25) remains stuck in the Golgi-TGN area with prof
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