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1

Figueira dos Anjos Oliveira, Edinéia, and Maria Lúcia Teixeira Garcia. "Mental Health Policy in the State of Espírito Santo, Brazil: Between Achievements and Disappointments." Best Practices in Mental Health 7, no. 2 (2011): 60–71. https://doi.org/10.70256/689047povmij.

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The Brazilian mental health policy proposes the organization of a full care network composed of instruments that provide psychosocial care to people with mental disorders. Each city or town should structure a group of programs to meet the mental health care demands and guarantee a local or regional referential service network. Data from the State Bureau indicate that forty-nine out of seventy-eight municipalities in Espírito Santo offer some mental health service (62.82%), and twenty-nine do not have any resource in this area (37.18%). This study analyzes the mental health municipal policy and
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Amiewalan, Florence O., and Frankie O. Balogun. "Foraminiferal analysis of AE-1 well, Agbada formation Onshore, Western Niger Delta Basin: Implication for biozonation and age dating." Global Journal of Pure and Applied Sciences 26, no. 2 (2020): 107–18. http://dx.doi.org/10.4314/gjpas.v26i2.3.

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Foraminiferal and sedimentological analysis was carried out using ditch cutting samples from intervals 2700 ft. - 10,185 ft. in AE-1 well. The samples were composited at 60 ft. into ninety four (94) ditch cutting samples. The standard micropaleontological sample procedures to recover the foraminiferal biofacies assemblages was utilized, followed by analysis and interpretation of the obtained results. The sedimentological analysis reveals five lithofacies - sandstone, sandy shale, shaly sand, mudstone and sandy clay which constitute part of the Agbada Formation of the Niger Delta. The foraminif
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Sing Turner, Valerie. "The Tao of Translation: Interpreting the Life of an Unsung Champion of Canadian Theatre." Canadian Theatre Review 139 (July 2009): 80–84. http://dx.doi.org/10.3138/ctr.139.012.

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ToyoshiYoshihara. Though he isn’t a household name in Canada, he ought to be – at least among those who value Canadian theatre. Because this slight, retiring Japanese gentleman has literally translated his passion for Canadian plays into a thriving theatre industry in Japan. Case in point: nine of his translations are being produced in Japan in 2009, eight of which are Canadian plays: Anne Chislett’s Another Season’s Promise, Wajdi Mouawad’s Scorched and Carole Frechette’s John and Beatrice, all of which are receiving their Japanese premieres; Colin Thomas’s One Thousand Cranes, George F. Walk
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Anuar, Nur A. A., Raflis R. Awang, Ee T. Khoo, Daphne Anthonysamy, Nor A. H. Darail, and Nor A. Emran. "Pedicled transverse rectus abdominis myocutaneous flap breast reconstruction: Hospital Kuala Lumpur’s early experience." International Surgery Journal 8, no. 10 (2021): 2872. http://dx.doi.org/10.18203/2349-2902.isj20213966.

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Background: Breast reconstruction is traditionally performed by the plastic surgeons. In the last four years, we have embarked on autologous breast reconstruction. We conducted a retrospective study to evaluate the complications and cosmetic outcomes of a pedicled transverse rectus abdominis myo-cutaneous (TRAM) flap breast reconstruction.Methods: We enrolled forty-one patients who underwent a TRAM flap reconstructive surgery between January 2016 and January 2020 at the hospital Kuala Lumpur, Malaysia. Thorough retrospective reviews of medical records were performed. Patient’s satisfaction on
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Ljunggren, Bengt, Hans Säveland, Lennart Brandt, and Stefan Zygmunt. "Early operation and overall outcome in aneurysmal subarachnoid hemorrhage." Journal of Neurosurgery 62, no. 4 (1985): 547–51. http://dx.doi.org/10.3171/jns.1985.62.4.0547.

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✓ Over a 3-year period, 251 individuals in a population of 1.46 million were known to have suffered an aneurysmal subarachnoid hemorrhage (SAH). Forty-three individuals (17%) were either found dead or were dead on arrival at a hospital or forensic department. Forty-nine patients (20%) were at no stage in their clinical course considered to be surgical candidates. Six patients (2% of the total series) were initially in good condition, but subsequently deteriorated during the acute phase and were not treated surgically. Nineteen poor-risk patients (8% of the total series) underwent emergency sur
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Maricle, Robert A., J. David Kinzie, and Peter Lewinsohn. "Medication-Associated Depression: A Two and One-Half Year Follow-up of a Community Sample." International Journal of Psychiatry in Medicine 18, no. 3 (1989): 283–92. http://dx.doi.org/10.2190/5mwp-ejb2-l81k-jtyt.

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A community sample of forty subjects (of a total of 5 0) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depre
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Yilwa, Victoria Moltong. "The Pattern of Distribution of ABO Blood Groups in Kaduna Metropolis, Nigeria." Malaysian Journal of Medical and Biological Research 6, no. 1 (2019): 67–70. http://dx.doi.org/10.18034/mjmbr.v6i1.472.

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The study was undertaken to assess the distribution of the ABO blood groups in Kaduna metropolis, Nigeria. Blood group types of forty-three thousand, nine hundred and nineteen (43,919) people were collected from eight different hospitals in Kaduna metropolis over a period of four years. These hospitals are easily accessible by all groups and classes of people because of their location. Phenotypic and allelic frequencies were determined to understand the distribution pattern of the ABO blood groups. A chi-square test was carried out to test whether the population was in Hardy-Weinberg equilibri
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Budha, Prem Bahadur. "Current State of Knowledge on Invasive and Alien Fauna of Nepal." Journal of Institute of Science and Technology 20, no. 1 (2015): 68–81. http://dx.doi.org/10.3126/jist.v20i1.13913.

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This study produced a comprehensive list of introduced fauna of Nepal. Of the sixty four species of alien fauna reported, there were seven species of mammals with forty improved breeds of cow, buffalo, goat, sheep and pig, six species of birds with eight breeds of chicken and duck, nineteen species of fish, twenty two species of arthropods including one species of freshwater prawn and twenty one species of insects, nine species of molluscs and one species of platyhelminths. Among reported alien species Achatina fulica, Capra hircus, Clarius batrachus, Cyprinus carpio, Gambusia affinis, Oncoryn
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Freeman, Michael D., Arthur C. Croft, Annette M. Rossignol, Christopher J. Centeno, and Whitney L. Elkins. "Chronic Neck Pain and Whiplash: A Case-Control Study of the Relationship between Acute Whiplash Injuries and Chronic Neck Pain." Pain Research and Management 11, no. 2 (2006): 79–83. http://dx.doi.org/10.1155/2006/304673.

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The authors undertook a case-control study of chronic neck pain and whiplash injuries in nine states in the United States to determine whether whiplash injuries contributed significantly to the population of individuals with chronic neck and other spine pain.Four hundred nineteen patients and 246 controls were randomly enrolled. Patients were defined as individuals with chronic neck pain, and controls as those with chronic back pain. The two groups were surveyed for cause of chronic pain as well as demographic information. The two groups were compared using an exposure-odds ratio. Forty-five p
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Komdeur, Prashant, Thijs T. Wingelaar, and Rob A. van Hulst. "A survey on the health status of Dutch scuba diving instructors." Diving and Hyperbaric Medicine Journal 51, no. 1 (2021): 18–24. http://dx.doi.org/10.28920/dhm51.1.18-24.

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Introduction: As the diving population is ageing, so are the diving instructors. Health issues and the use of prescribed medications are more common when ageing. The death of two diving instructors during one weekend in 2017 in the Netherlands, most likely due to cardiovascular disease, motivated investigation of the prevalence of relevant comorbidities in Dutch diving instructors. Methods: All Dutch Underwater Federation diving instructors were invited to complete an online questionnaire. Questions addressed diving experience and current and past medical history including the use of medicatio
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Santolin, Ísis Daniele Alves Costa, Hermes Ribeiro Luz, Nívea Maria Alchorne, et al. "Ticks on birds caught on the campus of the Federal Rural University of Rio de Janeiro, Brazil." Revista Brasileira de Parasitologia Veterinária 21, no. 3 (2012): 213–18. http://dx.doi.org/10.1590/s1984-29612012000300007.

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The prevalence of parasitic infections, particularly those caused by ectoparasites, may influence the biology and ecology of wild birds. The aim of this study was to investigate occurrences and identify the species of ticks collected from wild birds caught on the campus of the Federal Rural University of Rio de Janeiro. The birds were caught using mist nets between October 2009 and December 2010. In total, 223 birds were caught, represented by 53 species and 19 families in nine orders. Nineteen birds (n = 7 species) were parasitized by immature ticks (prevalence of 8.5%). Forty-four ticks were
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Katoch, Naveen, Rishav Kumar, Anil Handa, Chidembra Bhardwaj, Aditi Sharma, and Devinder Kumar Mehta. "Serological Detection of Cucumber Mosaic Virus and Capsicum Chlorosis Virus in Pepper (Capsicum annuum L.) Germplasm." Journal of Advances in Biology & Biotechnology 27, no. 10 (2024): 1320–26. http://dx.doi.org/10.9734/jabb/2024/v27i101552.

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A survey was conducted on the basis of symptomatology for the screening of germplasm under insect proof glasshouse conditions in the Department of Vegetable Science, Dr. YSPUHF, Nauni, Solan to identify the sources of resistance in pepper crop. The most prominent symptoms were mosaic, mottling, leaf narrowing, stunted growth, mosaic with chlorotic lesions, formation of rings with necrotic lesions and mosaic with mottling. Forty-eight varieties or breeding lines were screened for the presence or absence of virus through DAS-ELISA. The study revealed that nineteen varieties or breeding lines tes
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Degiannis, Elias, Douglas M. Bowley, Frank Bode, et al. "Ballistic Arterial Trauma to the Lower Extremity: Recent South African Experience." American Surgeon 73, no. 11 (2007): 1136–39. http://dx.doi.org/10.1177/000313480707301112.

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The aim of this study was to determine the current outcome of gunshots to the arteries of the lower extremity. The authors conducted a retrospective analysis of 104 patients with gunshots to the femoral (n = 71) and popliteal (n = 33) artery. One hundred four patients presented over the 60-month period. Ninety-six (92%) were male and eight of 104 female. Ninety-nine were gunshot injuries, five from shotguns. Nine patients had injury to the common femoral artery, 62 patients had injury to the superficial femoral artery, and 33 had popliteal artery injury. One patient died in the emergency room
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Kubota, Akio, Akira Okada, Yuichi Fukui, Hisayoshi Kawahara, Kenji Imura, and Shinkichi Kamata. "Indocyanine Green Test Is a Reliable Indicator of Postoperative Liver Function in Biliary Atresia." Journal of Pediatric Gastroenterology and Nutrition 16, no. 1 (1993): 61–65. http://dx.doi.org/10.1002/j.1536-4801.1993.tb10802.x.

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SummaryIn order to evaluate liver function in postoperative biliary atresia (BA) patients, the indocyanine green (ICG) clearance test was performed. Nineteen patients, ranging in age from 2 to 9 years, were classified into three groups. Group I were those who had no jaundice throughout the postoperative period (n = 9), Group II were those who had recurrent or intermittent jaundice (n = 7), and Group III were those who had persistent jaundice after hepatic portojejunostomy (n = 3). Forty‐four volunteers of comparative age and sex served as controls to establish a normal range of ICG‐K values in
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Dr., Sana Tariq Dr. Farwa Liaqat Dr. Maryam Fatima. "AGE IMPACT ON THE RESULT OF KIDNEY TRANSPLANTATION." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 06 (2019): 12029–33. https://doi.org/10.5281/zenodo.3246895.

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<strong><em>Objectives: </em></strong><em>This research was aimed to assess the age impact on kidney Tx (Transplantation) outcome &amp; survival of graft and compassion of the old population with young population. </em> <strong><em>Methodology: </em></strong><em>A sum of nineteen hundred and forty-six-kidney transplant carried out from one thousand five hundred and thirty-seven living &amp; four hundred and nine cadaveric donors from March 2016 to April 2018. The division of the recipients carried out into two groups in accordance with their age at the instance of Tx. First group of youngsters
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Spałek, Maciej Marek, Magdalena Jałowska, Natalia Welc, Monika Bowszyc-Dmochowska, and Marian Dmochowski. "Dapsone as a Current Option for the Treatment of Autoimmune Bullous Diseases with Autoimmunity to Non-Enzymes: A Retrospective Study from a Single Central European Referral Center." Medicina 60, no. 8 (2024): 1324. http://dx.doi.org/10.3390/medicina60081324.

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Background and Objectives: Dapsone (DP) is employed in the management of various skin conditions, including autoimmune bullous diseases to non-enzymes (n-eAIBDs). This study aimed to assess the advantages and safety profile of DP treatment in n-eAIBDs patients. The evaluation focused on clinical remission, reduction in glucocorticosteroid (GCS) usage, and adverse incidents during a 12-month observation in a dermatology department at a Central European university. Materials and Methods: Our retrospective study included forty-one patients who met the inclusion criteria, comprising nineteen with
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Sayej, Wael N., Razan AlKhouri, Robert D. Baker, Raza Patel, and Susan S. Baker. "Esophagitis in Children with Celiac Disease." ISRN Gastroenterology 2011 (July 13, 2011): 1–3. http://dx.doi.org/10.5402/2011/489065.

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Objectives. To our knowledge, the occurrence of esophagitis in children with celiac disease (CD) has never been evaluated. The aim of this study is to determine the prevalence of esophagitis in children with CD. Patients and Methods. Between 2003 and 2007, children with biopsy confirmed CD were retrospectively identified. Biopsy reports were reviewed for esophageal inflammation. Biopsy reports of 2218 endoscopies performed during the same period were also evaluated for inflammation. Results. Forty-nine children diagnosed with CD (47% boys). Nineteen of 49 (39%) patients with CD had esophagitis
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Logothetis, C. J., M. L. Samuels, D. E. Selig, et al. "Chemotherapy of extragonadal germ cell tumors." Journal of Clinical Oncology 3, no. 3 (1985): 316–25. http://dx.doi.org/10.1200/jco.1985.3.3.316.

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Forty-nine patients with histologically proven germ cell tumors arising in extragonadal sites were retrospectively reviewed. Included in the review were an additional seven patients with undifferentiated tumors with a pathologic appearance compatible with that of a germ cell tumor and elevated levels of serum biomarkers (beta subunit of human chorionic gonadotropin [beta-HCG] +/- alpha-fetoprotein [AFP]. Nineteen patients had a pure seminoma arising in an extragonadal site, whereas 30 patients had nonseminomatous germ cell tumors. Seven patients had primary undifferentiated tumors with elevate
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Rehak, Matus, Catharina Busch, Jan-Darius Unterlauft, Claudia Jochmann, and Peter Wiedemann. "Outcomes in diabetic macular edema switched directly or after a dexamethasone implant to a fluocinolone acetonide intravitreal implant following anti-VEGF treatment." Acta Diabetologica 57, no. 4 (2019): 469–78. http://dx.doi.org/10.1007/s00592-019-01439-x.

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Abstract Aims Fluocinolone acetonide (FAc) is an intravitreal corticosteroid implant approved for the second-line treatment of diabetic macular edema (DME). This study compared outcomes of patients with DME switched directly to an FAc implant, versus indirectly via dexamethasone, after anti-VEGF therapy failure. Methods This is a retrospective, single-center chart review. Patients were assigned to Group A (switched to FAc after anti-VEGF) or Group B (switched to dexamethasone and then to FAc after &gt; 4 months). Charts were reviewed for best-corrected visual acuity (BCVA), central macular thi
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Zhang, Man-Li, Ling-Qian Wang, Yong Qi, Yi Wu, Dong-Hui Zhou, and Lu-Lin Li. "Comparative genomic analysis of three geographical isolates from China reveals high genetic stability of Plutella xylostella granulovirus." PLOS ONE 16, no. 1 (2021): e0243143. http://dx.doi.org/10.1371/journal.pone.0243143.

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In this study, the genomes of three Plutella xylostella granulovirus (PlxyGV) isolates, PlxyGV-W and PlxyGV-Wn from near Wuhan and PlxyGV-B from near Beijing, China were completely sequenced and comparatively analyzed to investigate genetic stability and diversity of PlxyGV. PlxyGV-W, PlxyGV-B and PlxyGV-Wn consist of 100,941bp, 100,972bp and 100,999bp in length with G + C compositions of 40.71–40.73%, respectively, and share nucleotide sequence identities of 99.5–99.8%. The three individual isolates contain 118 putative protein-encoding ORFs in common. PlxyGV-W, PlxyGV-B and PlxyGV-Wn have te
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Savage, Naomi. "The Housing Project: Working Collaboratively with Adolescents in Theatre and Education." Canadian Theatre Review 133 (March 2008): 62–69. http://dx.doi.org/10.3138/ctr.133.009.

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The Toronto District School Board’s (TDSB) Theatre in Education Co-op was first introduced to the former Toronto Board nineteen years ago by Kathy Lundy, who was then an instructional leader for Dramatic Arts.1 The mandate of the program is for students to work with a director from February until June to create collectively a thirty- to forty-five-minute play that will tour approximately thirty TDSB middle schools. Typically, the play addresses a social issue that is relevant to a middle school audience. Students meet at a designated rehearsal space from nine until four daily. Theatre Co-op is
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De Vos, Corné, L. Van Wyk, D. Sidler, and P. Goussard. "The 30-day outcome of neonates operated for esophageal atresia." Journal of Neonatal Surgery 11 (March 17, 2022): 12. http://dx.doi.org/10.47338/jns.v11.1049.

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Background: Despite great advances in the overall management of neonates with esophageal atresia (EA), many complications leading to morbidity still occurs. Most complications can be treated conservatively, but effective management is needed to reduce long-term morbidity. Methods: A retrospective cohort study was performed on neonates treated for EA with/without a tracheoesophageal fistula (TEF) between 2001 and 2020. Data were collected from patient records, discharge summaries, and surgical notes. The information recorded included: maternal and neonatal demographics, information regarding th
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Yeung, Fanny, Yuk Him Tam, Yuen Shan Wong, et al. "Early Reoperations after Primary Repair of Jejunoileal Atresia in Newborns." Journal of Neonatal Surgery 5, no. 4 (2016): 42. http://dx.doi.org/10.21699/jns.v5i4.444.

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Aim: To review nine-year experience in managing jejuno-ileal atresia (JIA) by primary resection and anastomosis and identify factors associated with reoperations.Methods: From April 2006 to May 2015, all consecutive neonates who underwent bowel resection and primary anastomosis for JIA were analyzed retrospectively. Patients with temporary enterostomy were excluded. Patient demographics, types of atresia, surgical techniques, need for reoperations, and long-term outcomes were investigated.Results: A total of forty-three neonates were included, in which nineteen (44.2%) of them were preterm and
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Crispin, Philip J., Bethany J. Crowe, and Anne M. McDonald. "Blood transfusion prescribing in the ACT: an insight into clinical decision making." Australian Health Review 29, no. 2 (2005): 240. http://dx.doi.org/10.1071/ah050240.

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This study aimed to determine the perspectives of a group of patients categorised as ?long-stay outliers? at a large South Australian metropolitan hospital about aspects of organisation of care and the perceived impact of long-term hospitalisation. Nineteen patients were interviewed using a semi-structured questionnaire. Eighty-nine percent of participants stated that they had no knowledge of how long they were to be in hospital. Forty-two percent indicated that they did not know when they would be discharged from hospital. This was of concern, especially considering the vulnerability of this
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Adiele, Dube, Chamisa Judith A, Gundani P. Morgan, Bako Catherine, and Lunga M. Carolyne. "Association of Academic Stress, Anxiety and Depression with Social-Demographic among Medical Students." International Journal of Social Science Studies 6, no. 6 (2018): 27. http://dx.doi.org/10.11114/ijsss.v6i6.3288.

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Background: Medical education programmes aim at producing wholesome of competent and skilled graduates, research have shown that students experience stress which impacts on their health, academic performance and social functioning. This paper aims to determine the extent of academic stress, depression and anxiety among medical undergraduates and to explore the correlation between academic stressors, psychological stress and socio-demographic background among first year medical students at National University of Science and Technology.Method: This descriptive cross-sectional study was undertake
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Ahvenjärvi, L., L. Mattila, R. Ojala, and O. Tervonen. "Value of multidetector computed tomography in assessing blunt multitrauma patients." Acta Radiologica 46, no. 2 (2005): 177–83. http://dx.doi.org/10.1080/02841850510012634.

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Purpose: To find out if multidetector computed tomography (MDCT), using a dedicated trauma protocol, provides sufficient diagnostic information of the injuries of blunt multitrauma patients to enable the planning of treatment for all body compartments. Material and Methods: One‐hundred‐and‐thirty‐three patients exposed to high‐energy trauma were referred and scanned with the standardized MDCT multitrauma protocol. The imaging protocol consisted of axial scanning of the head and helical scanning of the facial bones, cervical spine, thorax, abdomen, and pelvis. The scanning times were 12 s for t
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Gabkika, Bray Madoué, Naim Constant, Lhagadang Foumsou, and Sadjoli Damtheou. "Uterine rupture: risk factors and prognosis." World Journal of Advanced Research and Reviews 4, no. 2 (2019): 033–38. https://doi.org/10.5281/zenodo.4310068.

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Uterine rupture is a non-surgical breach of the continuity of the myometrial wall of the uterus.Objective: identify risk factors and evaluate the prognosis of uterine rupture.This was a descriptive and analytical study with retrospective data collection over a four-year period from January 1<sup>st</sup>, 2015 to December 31<sup>st</sup>, 2018.We recruited all cases of uterine rupture that met our criteria and matched them to the following case.The frequency of uterine rupture was 0.77%.&nbsp; The aged group from 25-34 were most represented with 69.5%. The average age was 27.1 &plusmn; 2.3 yea
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Northfelt, D. W., B. J. Dezube, J. A. Thommes, et al. "Efficacy of pegylated-liposomal doxorubicin in the treatment of AIDS-related Kaposi's sarcoma after failure of standard chemotherapy." Journal of Clinical Oncology 15, no. 2 (1997): 653–59. http://dx.doi.org/10.1200/jco.1997.15.2.653.

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PURPOSE To determine the efficacy and safety of pegylated-liposomal doxorubicin in patients with AIDS and Kaposi's sarcoma (AIDS-KS) who experienced failure of standard chemotherapy. METHODS Fifty-three patients with advanced AIDS-KS who experienced disease progression or intolerable toxicities while receiving standard doxorubicin/bleomycin/vincristine (ABV) or bleomycin/vincristine (BV) chemotherapy were identified from a cohort of patients who were then treated with pegylated-liposomal doxorubicin. Patients received 20 mg/m2 pegylated-liposomal doxorubicin (Doxil; Sequus Pharmaceuticals, Inc
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Pernot, H. F. M., G. M. M. Winnubst, J. J. M. Cluitmans, and L. P. de Witte. "Amputees in Limburg: Incidence, morbidity and mortality, prosthetic supply, care utilisation and functional level after one year." Prosthetics and Orthotics International 24, no. 2 (2000): 90–96. http://dx.doi.org/10.1080/03093640008726531.

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Objectives: To describe for the province of Limburg, the Netherlands, the incidence of lower limb amputation (LLA), the demographic characteristics of the amputees, reason and level of amputation, care the amputees receive, prosthetic supply and functional level after one year.Design: A prospective descriptive cohort study.Methods: Anonymized data on all amputees in all nine hospitals were collected during 1994. Followup was one year.Results: 191 major lower limb amputations in 164 patients. Incidence was 17.1 per 100,000. Amputation levels: 77 transtibial, 52 transfemoral and 43 knee disar
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Dube, A., J. Chamisa, P.M Gundani, C. Bako, and M.C Lunga. "Association of Academic Stress, Anxiety and Depression with Social-Demographic among Medical Students." International Journal of Social Science Studies 6, no. 6 (2018): 6. https://doi.org/10.11114/ijsss.v6i6.3288.

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Background: Medical education programmes aim at producing wholesome of competent and skilled graduates, research have shown that students experience stress which impacts on their health, academic performance and social functioning. This paper aims to determine the extent of academic stress, depression and anxiety among medical undergraduates and to explore the correlation between academic stressors, psychological stress and socio-demographic background among first year medical students at National University of Science and Technology. Method: This descriptive cross-sectional study was undertak
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Wasserheit, C., A. Frazein, R. Oratz, et al. "Phase II trial of paclitaxel and cisplatin in women with advanced breast cancer: an active regimen with limiting neurotoxicity." Journal of Clinical Oncology 14, no. 7 (1996): 1993–99. http://dx.doi.org/10.1200/jco.1996.14.7.1993.

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PURPOSE A phase II study of paclitaxel and cisplatin in patients with advanced breast cancer was performed to determine the objective response rate and make further observations about the toxicity of this regimen. PATIENTS AND METHODS Patients were required to have histologically proven adenocarcinoma of the breast with no more than one chemotherapeutic treatment for advanced disease. Treatment consisted of paclitaxel 200 mg/m2 administered as a 24-hour intravenous (i.v.) infusion followed by cisplatin 75 mg/m2 i.v. Patients received granulocyte colony-stimulating factor (G-CSF) 5 micrograms/k
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Zornow, Kailee A., Jennifer E. Slovak, Jonathan A. Lidbury, Jan S. Suchodolski, and Joerg M. Steiner. "Fecal S100A12 concentrations in cats with chronic enteropathies." Journal of Feline Medicine and Surgery 25, no. 3 (2023): 1098612X2311642. http://dx.doi.org/10.1177/1098612x231164273.

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Objectives The aim of this study was to compare fecal S100A12 concentrations in cats diagnosed with chronic enteropathy (CE) with healthy control cats. Methods This was a prospective, cross-sectional study. Forty-nine cats that had gastrointestinal signs for &gt;3 weeks and a complete diagnostic work-up, including bloodwork, abdominal ultrasound and upper and/or lower gastrointestinal endoscopic biopsies, were enrolled into the CE group. Nineteen cats from the CE group were diagnosed with inflammatory bowel disease (IBD) or chronic inflammatory enteropathy (CIE) and 30 with alimentary lymphoma
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Lyka, G. Pasinhon, B. Ta-asan Kyle, Reniel D. Bacani John, et al. "Differences in the Cast-Off Spatter Produced by Commonly used Instruments on Violent Crimes in Baguio City Utilizing the Developed Trebuchet." International Journal of Innovative Science and Research Technology 8, no. 4 (2023): 3024–35. https://doi.org/10.5281/zenodo.8280936.

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Bloodstain Pattern Analysis refers to the gathering, classification, and interpretation of the distribution and shape of bloodstains associated with a crime. Cast-off spatters are a crucial component of a practical, scientific, and medically based reconstruction of a crime since they provide a wealth of information. The focus of the study is to determine and compare the number of primary bloodstains, number of satellite stains, and the length of cast-off trail produced by a bolo, ice pick, butterfly knife, and kitchen knife. A trebuchet was constructed to swing the instrument simulating a pers
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Jun, Kong, Qin Ya-zhen, Zhao Xiao-su та ін. "Interferon-α may help prevent molecular relapse of chronic myeloid leukemia after the discontinuation of tyrosine kinase inhibitors". Therapeutic Advances in Hematology 12 (січень 2021): 204062072098664. http://dx.doi.org/10.1177/2040620720986643.

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Background: Currently, the goal of chronic myeloid leukemia (CML) treatment is normal survival and good quality of life without life-long treatment, namely, “treatment-free remission” (TFR). At present, approximately only 50% of patients with CML with a deep molecular response are able to discontinue tyrosine kinase inhibitor (TKI) without experiencing molecular relapse [MR; loss of major molecular response (MMR)]. In addition, prior interferon (IFN) treatment is associated with a higher rate of TFR. Methods: We aimed to evaluate the feasibility of TKI discontinuation in Chinese patients with
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Erker, Craig, Brandon Craig, Simon Bailey, et al. "MEDB-49. Relapsed SHH medulloblastomas in young children. Are there alternatives to full-dose craniospinal irradiation?" Neuro-Oncology 24, Supplement_1 (2022): i117. http://dx.doi.org/10.1093/neuonc/noac079.423.

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Abstract BACKGROUND/RATIONAL: Following initial irradiation sparing therapy, many young children with relapsed medulloblastoma can be salvaged with craniospinal irradiation (CSI). However, the interval to relapse is short and neurocognitive sequelae remain a major concern. The contribution of molecular subgrouping may help refine indications and modalities of salvage strategies in this population. METHOD: From a cohort of 151 young children with molecularly characterized relapsed medulloblastoma, subset analysis of the SHH medulloblastoma was conducted to describe the practice of salvage radio
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Smyth, Erin, Renee Appaneal, Michael Drew, et al. "Identifying the challenges to implementing a neuromuscular warm-up in pre-elite netball." International Journal of Sports Science & Coaching 16, no. 4 (2021): 913–24. http://dx.doi.org/10.1177/1747954121998462.

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Objective To identify challenges for implementing Netball Australia’s ‘Knee injury prevention for Netballers and Enhance performance and Extend play’ (KNEE) program for 17/U &amp; 19/U State (i.e. regional/provincial representative) teams. Design Concept mapping, a mixed-methods approach incorporating qualitative and quantitative data collection and analyses. Setting Pre-elite netball. Participants Thirty-nine netball coaches, strength &amp; conditioning coaches and physiotherapists working with State 17/U &amp; 19/U teams. Methods Participants brainstormed challenges to implementing the KNEE
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AFOLAYAN, Comfort O., and Michael Olugemi AWODIRAN. "Genetic Differentiation of Archachatina marginata Populations from Three Vegetation Zones Using Radom Amplified Polymorphic DNA Polymerase Chain Reaction." Notulae Scientia Biologicae 7, no. 3 (2015): 372–81. http://dx.doi.org/10.15835/nsb739601.

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The genetic differentiation of Archachatina marginata populations from three different zones of Nigeria was studied with a view to delimiting them into sub-species. One hundred and nineteen (119) snail specimens were collected, comprising of forty (40) specimens from Yenagoa (Mangrove forest) and from Kabba (Guinea Savanna) and thirty nine (39) specimens were from Ile-Ife (Rainforest). Eight parameters of the shell specimens of A. marginata which included height of shell, width of shell, aperture height, aperture width, spire length, spire width, penultimate whorl length and first whorl length
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Shakya, Kiran, Suprada Pokhrel Pandey, Ram Prasad Pokhrel, and Om Krishna Pokhrel. "Intraoperative visual experience and preoperative counselling during phacoemulsification under topical anaesthesia." Journal of Kathmandu Medical College 4, no. 2 (2016): 45–49. http://dx.doi.org/10.3126/jkmc.v4i2.15032.

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Background: Phacoemulsification surgery using topical anesthesia makes patient experience a multitude of visual sensations. However, it makes cataract surgery safe with the quickest visual recovery.Objective: To find the effect of preoperative counseling about potential intraoperative visual experience during phacoemulsification under topical anesthesia to alleviate fear in patients having cataract surgery.Methods: This non- randomized and non comparative study was carried out in a tertiary care hospital from February 2015 to April 2015. Forty five adult patients underwent cataract surgery (ph
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Paudel, Ganga, Ramesh Raj Pant, Tark Raj Joshi, et al. "Hydrochemical Dynamics and Water Quality Assessment of the Ramsar-Listed Ghodaghodi Lake Complex: Unveiling the Water-Environment Nexus." Water 16, no. 23 (2024): 3373. http://dx.doi.org/10.3390/w16233373.

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Human activities and climate change increasingly threaten wetlands worldwide, yet their hydrochemical properties and water quality are often inadequately studied. This research focused on the Ghodaghodi Lake Complex (GLC) and associated lakes in Nepal, a Ramsar-listed site known for its biodiversity and ecological significance. The study was conducted to assess seasonal water quality, investigate the factors influencing hydrochemistry, and assess the lakes’ suitability for irrigation. Forty-nine water samples were collected from the GLC in pre-monsoon and post-monsoon periods. Nineteen physico
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Radeva, Demi, Gareth Hopkin, Elias Mossialos, John Borrill, Leeza Osipenko, and Huseyin Naci. "Assessment of technical errors and validation processes in economic models submitted by the company for NICE technology appraisals." International Journal of Technology Assessment in Health Care 36, no. 4 (2020): 311–16. http://dx.doi.org/10.1017/s0266462320000422.

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BackgroundEconomic models play a central role in the decision-making process of the National Institute for Health and Care Excellence (NICE). Inadequate validation methods allow for errors to be included in economic models. These errors may alter the final recommendations and have a significant impact on outcomes for stakeholders.ObjectiveTo describe the patterns of technical errors found in NICE submissions and to provide an insight into the validation exercises carried out by the companies prior to submission.MethodsAll forty-one single technology appraisals (STAs) completed in 2017 by NICE
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Pieters, Dorien J., Peter L. Zock, Dagmar Fuchs та Ronald P. Mensink. "Effect ofα-linolenic acid on 24-h ambulatory blood pressure in untreated high-normal and stage I hypertensive subjects". British Journal of Nutrition 121, № 2 (2018): 155–63. http://dx.doi.org/10.1017/s0007114518003094.

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AbstractResults of intervention studies on the effects ofα-linolenic acid (ALA; C18 : 3n-3) on blood pressure (BP) are conflicting. Discrepancies between studies may be due to differences in study population, as subjects with increased baseline BP levels may be more responsive. Therefore, we examined specifically the effects of ALA on 24-h ambulatory blood pressure (ABP) in (pre-)hypertensive subjects. In a double-blind, randomised, placebo-controlled parallel study, fifty-nine overweight and obese adults (forty males and nineteen females) with (pre-)hypertension (mean age of 60 (sd8) years) r
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Biswas, D., A. Rafferty, and P. Jassar. "Night emergency cover for ENT in England: a national survey." Journal of Laryngology & Otology 123, no. 8 (2009): 899–902. http://dx.doi.org/10.1017/s002221510900471x.

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AbstractObjectives:To evaluate the quality of out-of-hours ENT on-call cover by junior doctors, in view of the European Working Time Directive and the recent changes in the National Health Service workforce due to the ‘Modernising Medical Careers’ initiative, in England.Methods:We performed a national survey of first-on-call doctors for ENT, using a telephone questionnaire. Hospital contact details were sourced from the National Health Service website. The inclusion criterion was hospitals providing acute ENT facilities overnight in England.Results:One hundred and nineteen hospitals were conta
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Eichel, Vanessa, Sabrina Klein, Carolin Bootsveld, et al. "Challenges in interpretation of WGS and epidemiological data to investigate nosocomial transmission of vancomycin-resistant Enterococcus faecium in an endemic region: incorporation of patient movement network and admission screening." Journal of Antimicrobial Chemotherapy 75, no. 7 (2020): 1716–21. http://dx.doi.org/10.1093/jac/dkaa122.

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Abstract Objectives VRE are listed, by the WHO, among the leading resistant pathogens causing greatest public concern; hence the spread and transmission of VRE, especially in hospitalized patients, need to be monitored. Despite the advancements in typing methods since the implementation of WGS for outbreak investigations, data interpretation, especially for vancomycin-resistant Enterococcus faecium (VREfm) in an endemic setting, remains challenging. In this study we explored the potential added benefit of incorporating patient movement data and admission screening to accurately estimate the ma
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Chand, Pankaj, Sushil Rana Magar, Bishnu Babu Thapa, and Bikal Shrestha. "Primary Total Hip Replacement in A Military Hospital in Kathmandu." Journal of Nepal Medical Association 56, no. 205 (2017): 158–62. http://dx.doi.org/10.31729/jnma.3033.

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Introduction: Total hip replacement is one of the most widely performed and amongst the most successful orthopedic procedures performed worldwide. Even though it is a common orthopedic procedure in developed nations, it is performed only in selected centers in Nepal. This study will review the functional outcome of total hip replacements carried out in Shree Birendra Hospital.&#x0D; Methods: We reviewed the records of total hip replacements, which were carried out in Shree Birendra Hospital, Kathmandu. Twenty-one hips were cemented and nineteen were uncemented. Cases were followed up in six we
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Sedlack, Jeffrey D., and Russell J. Nauta. "Primary Hepatocellular Carcinoma: Hospital Based Epidemiologic Study." HPB Surgery 3, no. 1 (1990): 11–19. http://dx.doi.org/10.1155/1990/84213.

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From 1968-1985 a series of thirty-seven patients with primary hepatocellular carcinoma was collected from the tumor registry of the Fairfax County Hospital, in the metropolitan Washington, D.C. area. These patients were found to have a mean age at diagnosis of sixty-two (males) to sixty-six (females). Thirty per cent of patients were previously cirrhotic and nineteen per cent had a history of viral hepatitis. There were no patients with documented birth control pill or steroid use. The most common presenting symptoms were anorexia and right upper quadrant pain. Liver-spleen scan was the most c
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Rughani, Richa, and Jennifer Parry. "Perceptions of foster carers regarding their oral health caregiving role for children in their care." Faculty Dental Journal 16, no. 2 (2025): 64–68. https://doi.org/10.1308/rcsfdj.2025.18.

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INTRODUCTION The most common reasons for being placed in care in England are abuse and neglect. Global research suggests that children in care and care leavers are disadvantaged in accessing dental services. Foster carers play an important part in managing and promoting oral health behaviours. METHODS This study provided an opportunity for foster carers to share their experiences of accessing dentistry, and the challenges in supporting oral health for the children and young people they look after. Fifty-four foster carers responded to a dental access survey distributed to in-house foster carer
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Berger, Assaf, Uri Hochberg, Alexander Zegerman, Rotem Tellem, and Ido Strauss. "Neurosurgical ablative procedures for intractable cancer pain." Journal of Neurosurgery 133, no. 1 (2020): 144–51. http://dx.doi.org/10.3171/2019.2.jns183159.

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OBJECTIVECancer patients suffering from severe refractory pain may benefit from targeted ablative neurosurgical procedures aimed to disconnect pain pathways in the spinal cord or the brain. These patients often present with a plethora of medical problems requiring careful consideration before surgical interventions. The authors present their experience at an interdisciplinary clinic aimed to facilitate appropriate patient selection for neurosurgical procedures, and the outcome of these interventions.METHODSThis study was a retrospective review of all patients who underwent neurosurgical interv
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Yaya, Kane, Leye Mamadou Mokhtar Mbacké, Zeinabou Maiga Moussa Tondi, et al. "Décentralisation De La Dialyse Au Sénégal : Expérience D’1 An Du Centre De Tambacounda A l’Est Du Pays." European Scientific Journal, ESJ 12, no. 36 (2016): 164. http://dx.doi.org/10.19044/esj.2016.v12n36p164.

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Hemodialysis has made numerous and significant progress in recent decades resulting in life expectancy increase (thirty or forty years). The aim of our study was to assess the treatment of acute and chronic hemodialysis in the reference center of Tambacounda. Patients and methods: This was a prospective study over a one-year period (April 2013 to March 2014) in the hemodialysis center of the regional hospital of Tambacounda, 450km away from Dakar. The study focused on epidemiological, clinical, paraclinical and scalable data. Results: Fifty-nine patients were involved in the study. The sex rat
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Lolli, Elisabetta, Elena De Cristofaro, Irene Marafini, et al. "Endoscopic Predictors of Neoplastic Lesions in Inflammatory Bowel Diseases Patients Undergoing Chromoendoscopy." Cancers 14, no. 18 (2022): 4426. http://dx.doi.org/10.3390/cancers14184426.

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Dye-based chromoendoscopy (DCE) with targeted biopsies is recommended for surveillance of patients with long-standing inflammatory bowel diseases (IBD), but endoscopic features that predict dysplasia are not fully clarified. We here aimed at identifying predictive factors of dysplastic/neoplastic lesions in IBD patients undergoing DCE. Two-hundred-and-nineteen patients were consecutively and prospectively enrolled from October 2019 to March 2022. One-hundred-and-forty-five out of 219 patients underwent DCE, and 148 lesions were detected in 79/145 (54%) patients. Thirty-nine lesions (26%) were
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Munhoz, Alexandre Mendonça. "Reoperative Transaxillary Approach Algorithm: Extending the Surgical Alternatives for Secondary Breast Augmentation in the Era of Scarless Surgery." Aesthetic Surgery Journal 40, no. 11 (2020): 1179–92. http://dx.doi.org/10.1093/asj/sjz339.

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Abstract Background Although the transaxillary approach (TAA) is useful in primary breast augmentation (BA) surgery, drawbacks of this technique include the need to correct complications arising from reuse of the axillary incision. Objectives The purpose of this study was to assess the outcomes of secondary BA procedures performed via the TAA in a cohort of patients operated on by a single surgeon and to provide an algorithm for reoperative TAA technique selection. Methods Sixty-two patients (122 breasts) underwent secondary TAA BA, which was indicated for capsular contracture (CC) in 35 patie
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