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1

Wang, Zhenggang. "Improved algorithm for entropic segmentation of DNA sequence /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?PHYS%202004%20WANG.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2004.<br>Includes bibliographical references (leaves 56-58). Also available in electronic version. Access restricted to campus users.
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2

Siu, Kim-Man. "A computational estimation of errors in model genomes using exactly duplicated DNA sequences /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?MATH%202005%20SIU.

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3

Ngwira, Patricia. "Nucleotide sequence diversity in maize and grass-infecting streak geminiviruses: A basis for nucleotide sequence classification and identification /." The Ohio State University, 1997. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487945015618607.

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4

Cai, Zheng. "Repetitive sequence analysis for soybean genome sequences." Diss., Columbia, Mo. : University of Missouri-Columbia, 2005. http://hdl.handle.net/10355/4249.

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Thesis (M.S.)--University of Missouri-Columbia, 2005.<br>"May 2005" The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Includes bibliographical references.
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5

Mohamed, Maizan. "Sequence analysis of the small (s) RNA segment of viruses in the genus Orthobunyavirus." Thesis, St Andrews, 2007. http://hdl.handle.net/10023/434.

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6

Huckle, James William. ""Prokaryotic Metallothionein gene isolation, Nucleotide sequence and expression"." Thesis, Durham University, 1993. http://etheses.dur.ac.uk/5662/.

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Metallothioneins (MTs) are low molecular weight, cysteine-rich, metal-binding proteins, which are proposed to have roles in essential trace metal homoeostasis and in the detoxification of metal ions. The genes encoding MTs have been isolated from a wide range of eukaryotes, although MT genes have not previously been isolated from prokaryotes. The polymerase chain reaction (PGR) was initially used to isolate a prokaryotic MT gene fragment from Synechococcus PCC 6301. PGR fragments were amplified using inosine-containing primers designed from the amino acid sequence of a prokaryotic MT. Subseque
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7

Earle, John Alexander Philip. "The nucleotide sequence of a bovine enterovirus genome." Thesis, Queen's University Belfast, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317112.

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8

Halsall, John Richard. "Isolation and characterisation of the B42 mating type locus of Coprinus cinereus." Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:d5340e8b-29d7-4418-be27-f0c06e10ca18.

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C. cinereus, any two of which are sufficient to promote B-regulated development following cell fusion. The isolation of the B42 locus is described along with the DNA sequence analysis that identified nine B mating type genes within a 27kb B42 -specific DNA sequence. Six of the genes, with small transcripts of 800-900nt, encode the mating pheromone precursors and the other three, with 1.9 to 2-5kb transcripts, encode the transmembrane pheromone receptors. The genes are arranged in three groups, designated group 1, 2 and 3, each consisting of one receptor gene and two pheromone genes. B42 and B6
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9

Musgrave-Brown, Esther. "Development and application of methods for targeted DNA sequencing of pooled samples." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648613.

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10

Cheng, Kai-hong. "Further development of the visual genome explorer a visual genomic comparative tool /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23242437.

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11

Alley, Stephen Charles. "The sequence-dependence of DNA flexibility /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/8678.

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12

Eubanks, Aleida C. (Aleida Christine). "Nucleotide Sequence of a Bovine Arginine Transfer RNA Gene." Thesis, University of North Texas, 1996. https://digital.library.unt.edu/ark:/67531/metadc278753/.

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A single plaque-pure lambda clone designated λBA84 that hybridized to a ˆ32P-labeled bovine arginine tRNA was isolated from a bovine genomic library harbored in a lambda bacteriophage vector. A 2.3-kilobase segment of this clone was found to contain an arginine transfer RNAccg gene by Southern blot hybridization analysis and dideoxyribonucleotide DNA sequencing. This gene contains the characteristic RNA polymerase III split promoter sequence found in all eukaryotic tRNAs and a potential RNA polymerase III termination site, consisting of four consecutive thymine residues, in the 3'-flanking reg
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13

Didelot, Xavier. "Inference of bacterial microevolution from large scale DNA sequence datasets." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670148.

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14

Coles, Leeanne Susan. "Chicken histone H1 genes /." Title page, table of contents and summary only, 1986. http://web4.library.adelaide.edu.au/theses/09PH/09phc693.pdf.

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15

Kam, Sin-yee. "Application of 16S rRNA gene sequencing in laboratory diagnosis of mycobacteria other than tuberculosis." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31971052.

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16

Christensen, Shawn A. "Assessment of Chenopodium quinoa Willd. genetic diversity in the USDA and CIP-FAQ collections using SSR's and SNP's /." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd1118.pdf.

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17

金倩儀 and Sin-yee Kam. "Application of 16S rRNA gene sequencing in laboratory diagnosis of mycobacteria other than tuberculosis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31971052.

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18

Krishnan, Vandhana. "Computational approaches for comparative genomics and transcriptomics using 454 sequencing technology." Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Thesis/Summer2009/v_krishnan_072409.pdf.

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Thesis (M.S. in computer science)--Washington State University, August 2009.<br>Title from PDF title page (viewed on Aug. 12, 2009). "School of Electrical Engineering and Computer Science." Includes bibliographical references (p. 80-87).
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19

Wang, Xiaofei. "Molecular characterization and cytogenetic analysis of chicken repetitive DNA sequences /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20979393.

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20

Local, Andrea. "Cloning of Carbonic Anhydrase from Cotton (Gossypium hirsutum L.)." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc279044/.

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Carbonic anhydrase is a ubiquitous zinc-metalloenzyme that catalyzes the interconversion of carbon dioxide and carbonate and has been found to play a wide range of roles in animals, plants and bacteria. Cotton genomic and cDNA libraries were screened for the plastidial isoform of carbonic anhydrase. The nucleotide sequences of two 1.2 Kb partial cDNA clones were determined. These clones exhibit high homology to carbonic anhydrases from other dicot plants and possess all the expected peptide motifs. For example, serine and threonine rich chloroplastic targeting peptide and conserved zinc bindin
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21

Lee, Hong-seng Daniel, and 李康善. "Foldback DNA: nucleotide sequence and characterization of MboII repeated sequences in human long foldbackDNA by molecular cloning and hybridization." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B31231251.

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22

Ganapathy, Ashwin. "Computational analysis of protein identification using peptide mass fingerprinting approach /." free to MU campus, to others for purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p1426056.

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23

Ryan, Martin Denis. "Molecular cloning and nucleotide sequence studies on enterovirus type 70." Thesis, University of Leicester, 1985. http://hdl.handle.net/2381/35415.

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The molecular cloning of enterovirus type 70 (EV70) was achieved using the hybrid (vRNA:cDNA) cloning strategy. Recombinant plasmids containing EV70 sequences were identified by hybridization in situ. EV70 cDNAs were characterized by optical and Smith-Birnstie1 (1976) restriction mapping techniques. Hybridization and restriction mapping data showed that a series of overlapping, subgenomic EV70 clones spanning 7.25Kbp had been produced. EV70 cDNAs were isolated and fragmented by subsequent restriction or ultra-sonic shearing methods. cDNA fragments produced by these methods were sub-cloned into
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24

Lee, Hong-seng Daniel. "Foldback DNA : nucleotide sequence and characterization of MboII repeated sequences in human long foldback DNA by molecular cloning and hybridization /." [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12263643.

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25

Fullerton, Stephanie Malia. "Allelic sequence diversity at the human beta-globin locus." Thesis, University of Oxford, 1994. http://ora.ox.ac.uk/objects/uuid:da897e20-7dae-4c77-9c4d-0be69cb024e1.

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26

Holder, Mark Travis. "Using a complex model of sequence evolution to evaluate and improve phylogenetic methods." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3037500.

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27

Leung, Chi-ming. "Motif discovery for DNA sequences." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B3859755X.

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28

Wang, Tai-Chun. "Computational experiment for the solution of single nucleotide polymorphisms (SNPS) problems." Thesis, The University of Sydney, 2011. https://hdl.handle.net/2123/29228.

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Single Nucleotide Polymorphisms (SNPs) have recently received significant attention from researchers in different life science disciplines. The discovery of novel SNPs from expressed sequence tags could be an economical method for researchers when handling those species which do not have complete reference sequences. However, distinguishing sequence errors from putative SNPs is a significant problem for in silico methods. Previous researchers have indicated that series of SNPs from the same chromosome, called haplotypes, contain more information than individual SNPs. Thus, reconstructin
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29

Liakhovitch, Evgueni. "Genetic algorithm using restricted sequence alignments." Ohio : Ohio University, 2000. http://www.ohiolink.edu/etd/view.cgi?ohiou1172598174.

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30

Williams, Joseph Paul. "Sequencing and annotation of potential cis-acting transcription elements in the emb-9 gene promoter of caenorhabditis elegans /." MSU Only Available Electronically, 2009. http://purl.missouristate.edu/etd/Williams.Joseph-2009-SP.

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31

Sakamoto, Hidenori, and Yuichi Sasayama. "Nucleotide sequence of cDNA of bone-mineralizing hormone calcitonin in medaka (Teleostei)." Laboratory of Freshwater Fish Stocks Bioscience and Biotechnology Center Nagoya University, 2007. http://hdl.handle.net/2237/13830.

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32

Ng, Siu-Kin. "Lineage specific genomics features and insights into evolutionary pathways /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?BIEN%202007%20NG.

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33

招紹裘 and Siu-kau Chiu. "Granulicatella, abiotrophia, and gemella bacteremia characterized by 16S ribosomal RNA gene sequencing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B3197045X.

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34

鄭啓航 and Kai-hong Cheng. "Further development of the visual genome explorer: a visual genomic comparative tool." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B3122412X.

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35

Yeung, Shiu-yan, and 楊兆恩. "Update and evaluation of 16SpathDB, an automated comprehensive database for identification of medically important bacteria by 16S rRNA gene sequencing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193552.

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Identification of pathogens is one of the important duties of clinical microbiology laboratory. Traditionally, phenotypic tests are used to identify the bacteria. However, due to some limitations of the phenotypic tests, the bacteria may not be identified sometimes and cannot be identified promptly. 16S rRNA gene sequencing is a rapid and accurate method to achieve this target. It is especially useful for identify rare or slow growing bacteria. However, the interpretation of the 16S rRNA gene sequencing result is one of the challenging duties to laboratory technicians and microbiologists. Apar
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36

Li, Yaoman, and 李耀满. "Efficient methods for improving the sensitivity and accuracy of RNA alignments and structure prediction." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/195977.

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RNA plays an important role in molecular biology. RNA sequence comparison is an important method to analysis the gene expression. Since aligning RNA reads needs to handle gaps, mutations, poly-A tails, etc. It is much more difficult than aligning other sequences. In this thesis, we study the RNA-Seq align tools, the existing gene information database and how to improve the accuracy of alignment and predict RNA secondary structure. The known gene information database contains a lot of reliable gene information that has been discovered. And we note most DNA align tools are well developed. The
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37

Wang, Weixin, and 王煒欣. "A fast and accurate model to detect germline SNPs and somatic SNVs with high-throughput sequencing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/197115.

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The rapid development of high-throughput sequencing technology provides a new chance to extend the scale and resolution of genomic research. How to efficiently and accurately call genetic variants in single base level (germline single nucleotide polymorphisms (SNPs) or somatic single nucleotide variants (SNVs)) is the fundamental challenge in sequencing data analysis, because these variants reported to influence transcriptional regulation, alternative splicing, non-coding RNA regulation and protein coding. Many applications have been developed to tackle this challenge. However, the shallow dep
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38

Wang, Yi, and 王毅. "Binning and annotation for metagenomic next-generation sequencing reads." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208040.

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The development of next-generation sequencing technology enables us to obtain a vast number of short reads from metagenomic samples. In metagenomic samples, the reads from different species are mixed together. So, metagenomic binning has been introduced to cluster reads from the same or closely related species and metagenomic annotation is introduced to predict the taxonomic information of each read. Both metagenomic binning and annotation are critical steps in downstream analysis. This thesis discusses the difficulties of these two computational problems and proposes two algorithmic methods,
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39

Fritz, Markus Hsi-Yang. "Exploiting high throughput DNA sequencing data for genomic analysis." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610819.

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40

Van, Der Merwe Pieter de Wet. "UCTD." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96877.

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Thesis (MSc)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Zygophyllum orbiculatum Welwitsch ex Oliv. from Angola and Zygophyllum stapffii Schinz from Namibia were described in the late 1800’s. Recent comparisons of these two species revealed that they were morphologically very similar except that Zygophyllum orbiculatum has unifoliolate leaves and Zygophyllum stapffii has bifoliolate leaves. The similarity of these two species was investigated using nuclear ITS (Internal Transcribed Spacer, i.e. ITS1, 5.8SrDNA, ITS2) region sequence data as phylogenetic markers. Due to almost iden
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41

Shedlock, Andrew M. "Systematics and life history evolution of world anglerfishes (Teleostei: Lophiiformes) : molecular tests of morphological hypotheses /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/5341.

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42

Clevinger, Jennifer Ann. "Systematics of Silphium and its subtribe Engelmanniinae (Asteraceae : Heliantheae) /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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43

Chan, Yin-leung. "Identification of bacteria with ambiguous biochemical profiles by 16S ribosomal RNA gene sequencing." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk:8888/cgi-bin/hkuto%5Ftoc%5Fpdf?B23373209.

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44

Chiu, Siu-kau. "Granulicatella, abiotrophia, and gemella bacteremia characterized by 16S ribosomal RNA gene sequencing." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25151605.

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45

Mahmoud, Ahmed Abd-Rabbou. "Characterization of repeated DNA sequences in diploid Thinopyrum species /." free to MU campus, to others for purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3144438.

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46

Bou, Zeidan Nadim Georges. "Human miRNA Sequence Based Variations Database." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5350.

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MicroRNAs (miRNAs) are studied as key genetic elements that regulate the gene expression involved in different human diseases. Clinical sequence based variations like copy number variations (CNVs) affect miRNA biogenesis, dosage and target recognition that may represent potentially functional variants and relevant target bindings. To systematically analyze miRNA-related CNVs and their effects on related genes, a user-friendly free online database was developed to provide further analysis of co-localization of miRNA loci with human genome CNV regions. Further analysis pipelines such as miRNA-ta
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47

Peng, Yu, and 彭煜. "Iterative de Bruijn graph assemblers for second-generation sequencing reads." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B50534051.

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The recent advance of second-generation sequencing technologies has made it possible to generate a vast amount of short read sequences from a DNA (cDNA) sample. Current short read assemblers make use of the de Bruijn graph, in which each vertex is a k-mer and each edge connecting vertex u and vertex v represents u and v appearing in a read consecutively, to produce contigs. There are three major problems for de Bruijn graph assemblers: (1) branch problem, due to errors and repeats; (2) gap problem, due to low or uneven sequencing depth; and (3) error problem, due to sequencing errors. A prope
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48

Clarke, David Morgan. "Pyridine nucleotide transhydrogenase of Escherichia coli: nucleotide sequence of the pnt gene and characterization of the enzyme complex." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/27044.

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Based on the rationale that Escherichia coli cells harboring plasmids containing the pnt gene would contain elevated levels of enzyme, three clones were isolated bearing the transhydrogenase gene from the Clarke and Carbon colony bank. The three plasmids were subjected to restriction endonuclease analysis. A 10.4-kilobase restriction fragment which overlapped all three plasmids was cloned into pUC13. Examination of several deletion derivatives of the resulting plasmids and subsequent treatment with exonuclease BAL31 revealed that enhanced transhydrogenase expression was localized within a 3.05
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49

Gunyuzlu, Paul L. "The nucleotide sequence of the 3' terminus of soybean mosaic virus." Thesis, Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/53126.

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The nucleotide sequence of the 3' terminus of soybean mosaic virus (SMV) VA/G1 RNA has been determined by dideoxynucleotide sequencing of oligo(dT) primed cDNA cloned into a pUC19 cloning vector via EcoR1 linkers. One recombinant plasmid, pSMV49, identified by colony and dot-blot hybridization to ¹²⁵I-SMV RNA, contained an insert of 1443 nucleotides and had an open reading frame of 1119 nucleotides terminating 224 nucleotides from the 3' terminal poly(A) tract. The coat protein cistron identified by a glutamine:serine dipeptide cleavage site 792 nucleotides upstream from the termination sequen
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50

Garrison, Keith Earl. "Nucleotide sequence polymorphism in ancient cultivars of grape (Vitis vinifera L.) /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.

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