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Dissertationen zum Thema „Object characterization“

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1

LaPointe, Jamie. "Adaptive estimation techniques for resident space object characterization." Thesis, The University of Arizona, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10250698.

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<p> This thesis investigates using adaptive estimation techniques to determine unknown model parameters such as size and surface material reflectivity, while estimating position, velocity, attitude, and attitude rates of a resident space object. This work focuses on the application of these methods to the space situational awareness problem.</p><p> This thesis proposes a unique method of implementing a top-level gating network in a dual-layer hierarchical mixture of experts. In addition it proposes a decaying learning parameter for use in both the single layer mixture of experts and the dual
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LaPointe, Jamie J., and Jamie J. LaPointe. "Adaptive Estimation Techniques for Resident Space Object Characterization." Thesis, The University of Arizona, 2016. http://hdl.handle.net/10150/623263.

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This thesis investigates using adaptive estimation techniques to determine unknown model parameters such as size and surface material reflectivity, while estimating position, velocity, attitude, and attitude rates of a resident space object. This work focuses on the application of these methods to the space situational awareness problem. This thesis proposes a unique method of implementing a top-level gating network in a dual-layer hierarchical mixture of experts. In addition it proposes a decaying learning parameter for use in both the single layer mixture of experts and the dual-layer hierar
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3

Mandadi, Bharath Kumar Reddy. "Advanced Object Characterization and Monitoring Techniques Using Polarimetric Imaging." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1243780947.

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4

Biller, Beth A., Johanna Vos, Esther Buenzli, et al. "Simultaneous Multiwavelength Variability Characterization of the Free-floating Planetary-mass Object PSO J318.5−22." IOP PUBLISHING LTD, 2018. http://hdl.handle.net/10150/627034.

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We present simultaneous Hubble Space Telescope (HST) WFC3+Spitzer IRAC variability monitoring for the highly variable young (similar to 20 Myr) planetary-mass object PSO J318.5-22. Our simultaneous HST + Spitzer observations covered approximately two rotation periods with Spitzer and most of a rotation period with the HST. We derive a period of 8.6. +/-. 0.1 hr from the Spitzer light curve. Combining this period with the measuredvsinifor this object, we find an inclination of 56 degrees.2. +/-. 8 degrees.1. We measure peak-to-trough variability amplitudes of 3.4%. +/-. 0.1% for Spitzer Channel
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Flasseur, Olivier. "Object detection and characterization from faint signals in images : applications in astronomy and microscopy." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSES042.

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La détection et la caractérisation d’objets dans des images à faible rapport signal sur bruit est un problème courant dans de nombreux domaines tels que l’astronomie ou la microscopie. En astronomie, la détection des exoplanètes et leur caractérisation par imagerie directe depuis la Terre sont des sujets de recherche très actifs. Une étoile cible et son environnement proche (abritant potentiellement des exoplanètes) sont observés sur de courtes poses. En microscopie, l’holographie en ligne est une méthode de choix pour caractériser à faibles coûts les objets microscopiques. Basée sur l’enregis
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Lopes, Alex Cerqueira. "Máscaras: transformações em “Doroteia” de Nelson Rodrigues." Escola de Teatro, 2014. http://repositorio.ufba.br/ri/handle/ri/27042.

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Al, Hayek Marianne. "Modélisation optique de signatures spectrales et polarimétriques d'objets pour augmenter les performances d'un système de reconnaissance." Electronic Thesis or Diss., Brest, 2023. http://www.theses.fr/2023BRES0101.

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L’imagerie conventionnelle, qui se limite aux formes et couleurs des objets, montre ses limites en matière de reconnaissance. Pour améliorer les performances des systèmes d’imagerie, l’imagerie hyperspectrale et polarimétrique apporte une richesse d’informations, notamment des grandeurs physiques difficiles à obtenir autrement. Cela permet d’améliorer la détection, la caractérisation quantitative et la classification des objets. Cependant, le traitement des données complexes de ces modalités reste un défi. L’objectif de ce travail est de proposer une méthodologie générique pour analyser les si
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Fernandes, Lénia Janete Oliveira. "Characterization and identification of printed objects." Master's thesis, FCT - UNL, 2008. http://hdl.handle.net/10362/1763.

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A study about the physical appearance of pre-photographic, photomechanical, photographic and digital positive reflective prints was made, relating the obtained images with the history, materials and technology used to create them. The studied samples are from the Image Permanence Institute (IPI) study collection. The digital images were obtained using a digital SLR on a copystand and a compound light microscope, with different lighting angles (0º, 45ºand 90º) and magnifications from overall views on the copystand down to a 20x objective lens on the microscope. Most of these images were origina
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Goh, Jinzhong Jeremy [Verfasser], Denise [Gutachter] Manahan-Vaughan, and Klaus-Peter [Gutachter] Hoffmann. "Characterization of the effects of novel object-space information on synaptic plasticity in the hippocampal CA1 sub-region of freely behaving mice / Jinzhong Jeremy Goh ; Gutachter: Denise Manahan-Vaughan, Klaus-Peter Hoffmann ; International Graduate School of Neuroscience." Bochum : Ruhr-Universität Bochum, 2013. http://d-nb.info/1212660749/34.

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10

bin, Ahmad Khairuddin Taufiq. "Characterization of objects by fitting the polarization tensor." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/characterization-of-objects-by-fitting-the-polarization-tensor(1ee0de67-fdd4-4fae-ba00-3f2e4f3987a8).html.

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This thesis focuses on some mathematical aspects and a few recent applications of the polarization tensor (PT). Here, the main concern of the study is to characterize objects presented in electrical or electromagnetic fields by only using the PT. This is possible since the PT contains significant information about the object such as shape, orientation and material properties. Two main applications are considered in the study and they are electrosensing fish and metal detection. In each application, we present a mathematical formulation of the PT and briefly discuss its properties. The PT in th
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Delgado, Hugo. "Characterization and surface reconstruction of objects in tomographic images of composite materials." Master's thesis, Faculdade de Ciencias e Tecnologia, 2013. http://hdl.handle.net/10362/13141.

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Dissertação para obtenção do Grau de Mestre em Engenharia Informática<br>In the scope of the project Tomo-GPU supported by FCT / MCTES the aim is to build an interactive graphical environment that allows a Materials specialist to define their own programs for analysis of 3D tomographic images. This project aims to build a tool to characterize and investigate the identified objects, where the user can define search criteria such as size, orientation, bounding boxes, among others. All this processing will be done on a desktop computer equipped with a graphics card with some processing power.
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Toullier, Thibaud. "Simultaneous characterization of objects temperature and radiative properties through multispectral infrared thermography." Thesis, Rennes 1, 2019. http://www.theses.fr/2019REN1S038/document.

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L'utilisation de caméras infrarouges bas coûts pour la surveillance long-terme d'infrastructures est prometteuse grâce aux dernières avancées technologiques du domaine. Une mesure précise de la température des surfaces observées in-situ se heurte au manque de connaissance des propriétés radiatives de la scène. L'utilisation d'une instrumentation multi-capteurs permet d'affiner le modèle de mesure afin d'obtenir une estimation plus précise de la température. A contrario, il est montré qu'il est toujours possible d'exploiter des données climatiques en ligne pour pallier un manque de capteur. Des
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Ley, Clemens. "Forward looking logics and automata." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:d6eb0004-47b9-4e32-b6c9-7796afecabd5.

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This thesis is concerned with extending properties of regular word languages to richer structures. We consider intricate properties like the relationship between one-way and two-way temporal logics, minimization of automata, and the ability to effectively characterize logics. We investigate whether these properties can be extended to tree languages or word languages over an infinite alphabet. It is known that linear temporal logic (LTL) is as expressive as first-order logic over finite words [Kam68, GPSS80]. LTL is a unidirectional logic, that can only navigate forwards in a word, hence it is
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Carrizo, Carlos. "Hyperspectral and Polarimetric Imaging for Advanced Characterization of the Ocean Surface and Underwater Objects." Thesis, The City College of New York, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13425979.

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<p> Hyperspectral and polarimetric imaging of the ocean, both below and above the water surface, has increased the interest of the Ocean Color (OC) scientific community for decades in an attempt to answer questions related to climate change, monitoring of water quality, assessment of the impact of anthropogenic activities on marine life and underwater ecosystems, detection and characterization of underwater targets. These needs are recognized by worldwide efforts devoted to acquiring accurate time series measurements in open-ocean and coastal waters by OC satellite imagery to produce reliable
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Mommert, M., D. E. Trilling, D. Borth, et al. "FIRST RESULTS FROM THE RAPID-RESPONSE SPECTROPHOTOMETRIC CHARACTERIZATION OF NEAR-EARTH OBJECTS USING UKIRT." IOP PUBLISHING LTD, 2016. http://hdl.handle.net/10150/614713.

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Using the Wide Field Camera for the United Kingdom Infrared Telescope (UKIRT), we measure the near-infrared colors of near-Earth objects (NEOs) in order to put constraints on their taxonomic classifications. The rapid-response character of our observations allows us to observe NEOs when they are close to the Earth and bright. Here we present near-infrared color measurements of 86 NEOs, most of which were observed within a few days of their discovery, allowing us to characterize NEOs with diameters of only a few meters. Using machine-learning methods, we compare our measurements to existing ast
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Casadei, Valerio. "Experimental characterization of backscattering properties of UWB antennas in the presence of close objects." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/4073/.

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RTLS and RFID systems are becoming more and more important in several fields. When these systems meet the UWB technology, they can take advantage of each other strengths. Since nowadays a strong importance is given to the "green" technology, we chose to adopt a passive solution. In this case the backscattering modulation can be used to carry data. Therefore it is necessary to analyze the behavior of the antennas used as tags, when they are closed to dierent material objects. In particular, the antenna mode part has been deeply observed, as it is the crucial part of the signal regarding the b
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Afridi, Pirzada. "Syntheses & characterization of nanoZSM-5 & MOR zeolites, characterization of ZNS in the pore network of MOR." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:8117cf4f-0a27-4eff-a328-8558573fc3b8.

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This study was carried out on the synthesis of mordenite zeolite and ZSM-5 zeolite. In Chapter 3 reports the growth of ZnS nanoclusters in the pore channels of mordenite zeolite. ZnS as an important wide-band-gap (3.6 eV) semiconductor nanoclusters and have various technological applications such as photocatalysis, nonlinear optics, sensors, solar cells, injection lasers, flat panel displays, ultraviolet light emitting diodes (LED). Zeolites have several different applications in industries, such as in catalysis, ion exchange adsorption and gas separation. Zeolites are mostly used as a catalys
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Seet, Li Fong. "Characterization of the biological properties of FGF-9." Thesis, University of Oxford, 1996. http://ora.ox.ac.uk/objects/uuid:a46cee92-c179-4d22-b27b-0e67c3c85a37.

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The fibroblast growth factor family of polypeptides currently consists of nine structurally-related members. Cloning of the mouse homologue of the latest reported member of the family, FGF-9, is described in this study. Mouse Fgf9 exhibits a high level of sequence conservation with the human, rat and Xenopus counterparts. Of note is the lack of a hydrophobic signal peptide at the N-terminus of the coding sequence. The protein, however, appeared to be secreted by producer cells since a significant quantity of the protein could be purified from the culture supernatant of transfected cells. Membe
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Wang, Shanshan. "Synthesis and characterization of monolayer molybdenum disulphide." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:182cdf51-c6e2-40bc-abf8-8057130bc2f5.

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Monolayer molybdenum disulphide (MoS<sub>2</sub>) is a semiconductor with a direct bandgap of &Tilde;1.9 eV. Much research attention has been attracted to its potential applications in nanoelectronics and optoelectronics recently, all of which are based upon a scalable production of high-quality monolayer MoS<sub>2</sub> and the in-depth comprehension of its fundamental properties. The PhD project focused on developing chemical vapour deposition (CVD) methods to grow monolayer MoS<sub>2</sub> and its related two-dimensional (2D) vertical heterostructures with an understanding of the growth mec
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Xu, Diming. "Synthesis and characterization of mixed-metal germanates." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:8a6b4ca2-0824-4d9a-8907-b40537405c72.

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Mixed-metal germanates with the general formula ABB'Ge<sub>4</sub>O<sub>12</sub> have been synthesised using the ceramic method and their properties characterised by X-ray diffraction, neutron diffraction, dc and ac magnetometry, specific heat and Mossbauer spectroscopy. DFT calculations were conducted on two compounds ZrM<sub>2</sub>Ge<sub>4</sub>O<sub>12</sub> (M = Mn, Co). All compositions adopt a tetragonal structure (space group P4/nbm with the unit-cell parameters a = b ~ 2c). The cation A occupies the 2b site and is coordinated by eight oxide ions at the corners of a square antiprism wh
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Van, Essen-Fishman Lucy. "Character through interaction : Sophocles and the delineation of the individual." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:c23353ec-cc60-453e-8c58-b13d01840a19.

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In this thesis, I argue that Sophoclean characters take shape through a number of different kinds of interaction. On the most basic level, interaction occurs between characters; interactions between characters, however, provide a framework for interactions between those characters and a variety of more abstract concepts. These interactions, by allowing characters to situate themselves with respect to concepts such as, for example, the social roles which shape the society of the play, provide a more complex picture of the personalities depicted onstage; a fuller view of Antigone’s personality,
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Gelabert, Javier. "Investigation of ultra-wideband wireless communication inside electromagnetically ultra small confined environments." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:672f535d-431d-44be-88db-8dfbfd709247.

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Ultra-wideband (UWB) communication has been the subject of extensive research in recent years due to its unique capabilities and potential applications, particularly in short-range multiple access wireless communications. However, many important aspects of UWB-based communication systems have not yet been thoroughly investigated. The propagation of UWB signals inside very small enclosed environments is one of the important issues with significant impacts on the future direction, scope, and generally the extent of the success of UWB technology. The objective of this thesis is to obtain a more t
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Nelson, Geoffrey Winston. "Surface characterization and functional properties of carbon-based materials." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:f22b95ce-65f3-4d9e-ac3d-a88f6e142c1a.

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Carbon-based materials are poised to be an important class of 21st century materials, for bio-medical, bio-electronic, and bio-sensing applications. Diamond and polymers are two examples of carbon-based materials of high interest to the bio-materials community. Diamond, in its conductive form, can be used as an electrochemical bio-sensor, whilst its nanoparticle form is considered a non-inflammatory platform to deliver drugs or to grow neuronal cells. Polymers, especially when chemically modified, have been used extensively in biological environments, from anti-microbial use to drug delivery.
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Kiappes, John Leon. "Synthesis and biological characterization of natural and designed sugars." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:ccc0e4dd-a8b4-445b-9fee-260c35b0040d.

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Carbohydrates represent a keystone among biological molecules. Well known as a source of energy, sugars also form the backbone of various biopolymers, act as markers and receptors for cellular communication and modulate lipid and protein functions. As such a powerful class, carbohydrates represent a useful pool from which both nature and man have drawn structures to produce biologically active compounds with a variety of modes of action. Beyond their importance to biology, sugars have represented attractive synthetic targets to chemists given their densely functionalized scaffolds. The work pr
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Tan, Felicia. "Characterization of pilE antisense RNA in Neisseria meningitidis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:23d8f4c4-b423-4638-986b-b6b8e3fe95ec.

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Expression of Type four pili is important for colonization and virulence in Neisseria meningitidis, which is a major causative agent of bacterial meningitis and septicaemia. Pili mediate adhesion, twitching motility, DNA uptake, and can be subject to phase and antigenic variation (Av). Pilin expression and Av may be modulated in response to environmental cues; however, the mechanisms of regulation are still unclear. This work demonstrates the identification of a novel cis-encoded RNA on the antisense (AS) strand of pilE, which encodes the major pilin subunit. The AS promoter is conserved in di
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Yeh, Shaoyang Anthony. "Three-dimensional aligned fibrillar scaffolds : fabrication and characterization." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:4e83606f-134f-4cb0-a4a5-78dfc8b33010.

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Aligned fibrillar scaffolds (AFSs) have been widely studied for their application in regenerative medicine, providing possible transplantable tissue replacements for nerve, spinal cord, tendon, ligament, muscle, etc. However, researches in AFSs are technically challenging mainly due to the complex fabrication and characterization processes, especially when the AFSs are made to be fully three-dimensional (3D). As the structure is linked to the quality and function of the engineered tissue product, there is an urgent need for novel techniques to characterize AFSs non-invasively and non-destructi
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Peng, Yung-Kang. "Surface mapping of faceted metal oxides by chemical probe-assisted NMR for catalytic applications." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:7b56021f-71fb-437b-8c6b-0569705ef68e.

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Semiconductive metal oxides are of great importance in environmental remediation and electronics because of their ability to generate charge carriers when excited with appropriate energy. The electronic structure, light absorption and charge transport properties have made the transition metal oxides an attractive material as photocatalyst. Recently, facet-engineering by morphology control has been intensively studied as an efficient approach to further enhance their photocatalytic performance. However, various processing steps and post-treatments used in the preparation of facet-engineered par
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Cohen, Carla J. "Characterization of RNA aptamers that bind to HIV-1 gp120." Thesis, University of Oxford, 2006. http://ora.ox.ac.uk/objects/uuid:e218ac2d-7269-49b2-826e-15ab05b7c1a0.

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RNA aptamers with 2'-fluoro-pyrimidine chemistry were previously selected by in vitro evolution to bind to monomeric HIV-1 gp120 from the R5 strain BaL. A group of 36 novel aptamers were cloned and sequenced from the heterogeneous pool and were tested for their ability to bind to gp120. The diversity of the RNA secondary structure of these, and 27 aptamers isolated previously, was analysed using a bioinformatics approach. This showed that eight aptamers contain a common branched motif, and RNA mutagenesis indicated that this structure is probably required for gp120 binding. Chemically synthesi
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Zhu, Danni. "Characterization of nicotinic acid adenine dinucleotide phosphate (NAADP) binding proteins." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:cb3309e7-ad14-4c0b-a24c-c42d95b52845.

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Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent intracellular second messenger capable of inducing calcium release from acidic organelles and is responsible for many important physiological activities. It has been recognized that an intermediate protein is required for NAADP to mediate its calcium-mobilizing effect through two-pore channels (TPCs). However, the identity of the intermediate NAADP binding protein remains unknown. This thesis aims to identify the elusive NAADP binding proteins to further elucidate the molecular mechanism of NAADP signalling pathway. The first pa
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Lam, Andy Ka Ming. "Electrophysiological characterization of the human two-pore channel 2." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:3a16d16e-f692-40d7-87f7-920151896038.

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The Two-pore channel (TPC1-3) family represents a recently identified class of endolysosomal ion channels. TPCs were originally proposed to be promising candidate channels for NAADP-induced Ca<sup>2+</sup> release. However, subsequent studies have emerged to propose an alternative view where TPCs may be Na+-selective channels regulated by the lysosome-specific phosphoinositide PI(3,5)P2 or voltage in an isoform-dependent manner. This thesis asks the question of whether pharmacological and ion permeation properties of TPCs, in particular the human TPC2, may satisfy or may be consistent with the
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Szilágyi, Anna Tünde. "Structural characterization of liver fibrosis in magnetic resonance images." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:1860b1d9-2b10-409f-9220-e12b002a9e32.

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The overall clinical motivation of this thesis is to differentiate between the different stages of liver disease stratifying into: no disease, mild disease, and severe fibrosis using Magnetic Resonance Imaging (MRI). As a related aim, we seek to differentiate as much as possible pericellular and nonpericellular fibrosis. This latter is clinically important, but currently no method exists that is able to perform this. Quickly, we realised that these aims push low level image analysis beyond their current bounds and so a great deal of the thesis is dedicated to extending such techniques before t
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Albanna, Sarmad. "Design, Characterization, and Implementation of Optical Systems for Remote Sensing of the Atmosphere and Astrophysical Objects." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/594951.

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This dissertation investigates the optical design and characterization for two distinct remote sensing applications. The first application is focused on the high precision optical phase correction for the photonic Local Oscillator (LO) designed for the Atacama Large Millimeter Array (ALMA). The phase instability in the original fiber optics design scheme is characterized and a novel, singlemode fiber-based interferometric approach to measure and actively zero out the unwanted Photonic LO phase drift is introduced. The proposed technique is implemented and characterized by using a 16 km baselin
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Menad, Samia. "Assemblage permanent de micro-objets par diélectrophorèse associée à une méthode de couplage covalent." Thesis, Ecully, Ecole centrale de Lyon, 2014. http://www.theses.fr/2014ECDL0037/document.

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La réalisation de micro et nanomatériaux avec des propriétés contrôlées nécessite le développement de nouvelles voies d’élaboration dites ascendantes « ou Bottom-up ». Les travaux présentés dans ce manuscrit visent à maîtriser la formation d’agrégats de particules colloïdales et de cellules, avec des applications potentielles dans les domaines des biocapteurs, de la microélectronique, de l’optique et de l’ingénierie tissulaire. L’approche proposée pour assembler les particules en structures organisées se base sur l’emploi de la diélectrophorèse, reposant sur l’application d’un champ électrique
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Jafri, Syed Hassan Mujtaba. "Building Systems for Electronic Probing of Single Low Dimensional Nano-objects : Application to Molecular Electronics and Defect Induced Graphene." Doctoral thesis, Uppsala universitet, Tillämpad materialvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160630.

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Nano-objects have unique properties due to their sizes, shapes and structure. When electronic properties of such nano-objects are used to build devices, the control of interfaces at atomic level is required. In this thesis, systems were built that can not only electrically characterize nano-objects, but also allow to analyze a large number of individual nano-objects statistically at the example of graphene and nanoparticle-molecule-nanoelectrode junctions. An in-situ electrical characterization system was developed for the analysis of free standing graphene sheets containing defects created by
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Seong, Tae-Yeon. "Microstructural characterization of heteroepitaxial layers of III-V compound semiconductors." Thesis, University of Oxford, 1991. http://ora.ox.ac.uk/objects/uuid:77ce3d0d-dc9b-45ab-af6b-eeb66785b2e5.

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This work describes results obtained from TEM, TED and HREM studies of MBE and MOCVD InAS<sub>y</sub>Sb<sub>1</sub><sub>-</sub><sub>y</sub>, MOCVD In<sub>x</sub>Ga<sub>1</sub><sub>-</sub><sub>x</sub>As, MOCVD InP<sub>y</sub>Sb<sub>1</sub><sub>-</sub><sub>y</sub> and MOCVD GaP<sub>y</sub>Sb<sub>1</sub><sub>-</sub><sub>y</sub> layers which were grown over a wide range of conditions. These semiconductor layers are of considerable importance for a variety of applications in optoelectronic and high-speed devices. TEM/TED investigations showed that phase separation occurs in MBE InAsSb layers, resul
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Zhang, Chi. "The characterization and engineering of human antigen-specific cytotoxic T cells." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:38718489-9fa3-4fa5-b50d-547ccc9adeed.

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This D.Phil. thesis focuses on human antigen-specific cytotoxic T lymphocytes (CTLs). In the first part of the thesis, the impact of antigen stimulation strength on CTL activation was investigated by evaluating the global transcriptomes of a wellcharacterized CTL clone and some of its surface protein expressions, with particular focus on immune checkpoint receptors. Based on the gene differentiations, an 'EGR2-CCL1-4-1BB' pathway, which is sensitive to very low-strength antigen stimulation, was identified. We proposed to block CCL1/CCR8 for future cancer therapeutic treatment as this could be
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Lee, Yi Xin Fiona. "Purification and characterization of extracellular vesicles released from pluripotent stem cells." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:224c718f-cc91-4286-8d6b-a50107fc1f04.

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Extracellular vesicles (EVs) are nano-sized particles constitutively released from cells into biological fluids such as blood, plasma, saliva and urine. Interestingly, these vesicles contain genetic cargoes including proteins, RNA and bioactive lipids that can be functionally delivered and affect recipient cells. Hence, EVs are postulated to be an alternative source of cell-cell communication in both normal physiological systems and pathological situations. Recently, EVs from mesenchymal stem cells have been shown to promote regeneration of injured cells. Induced pluripotent stem cells (iPSCs)
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Chuang, Kai-Ting. "Characterization of mouse two-pore channels (TPCs) in NAADP-mediated Ca(2+) signalling." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:dbf87d55-4266-4fa9-9eef-5214e7f4cd01.

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Recent studies have identified Two-Pore Channels (TPCs) as the channels activated by NAADP. To date, most studies that characterized these channels have employed heterologous expression or overexpression systems. The research reported here has focused principally on endogenous TPC activity by using single and dual gene knockout (KO) in a mouse system and has yielded insights into TPC expression levels, subcellular localisation, NAADP binding, and channel function. Mouse models that had been generated by both the “gene-trapping” and the “genetargeting” techniques were obtained and validated. Th
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Serrano, Medina Sac Nicte Xiomara [Verfasser]. "Radio emission from massive Young Stellar Objects and their surroundings : Characterization and feedback / Sac Nicte Xiomara Serrano Medina." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1221668978/34.

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40

Berger, Karsten. "Discovery and Characterization of the first Low-Peaked and Intermediate-Peaked BL Lacertae Objects in the Very High Energy Gamma-Ray Regime." kostenfrei, 2009. http://www.opus-bayern.de/uni-wuerzburg/volltexte/2009/3743/.

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41

Teixeira, Ribeiro Rui Agostinho Fernandes. "Spectral analysis of breast ultrasound data with application to mass sizing and characterization." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:8768959f-cc5a-476d-b924-5a5d7df31b8d.

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Ultrasound is a commonly used imaging modality in diagnosis and pre-operative assessment of breast masses. However, radiologists often find it very difficult to correctly size masses using conventional ultrasound images. Consequently, there exists a strong need for more accurate sizing tools to avoid either the removal of an over-estimated amount of tissue or a second surgical procedure to remove margins involved by tumour not removed in the primary operation. In this thesis, we propose a new method of processing the backscattered ultrasound signals from breast tissue (based on the Fourier spe
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König, Dennis [Verfasser], Alfred [Gutachter] Ludwig, and Gunther [Gutachter] Eggeler. "Fabrication and characterization of nanoscale shape memory alloy objects / Dennis König ; Gutachter: Alfred Ludwig, Gunther Eggeler ; Fakultät für Maschinenbau." Bochum : Ruhr-Universität Bochum, 2014. http://d-nb.info/1229692681/34.

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43

Mousavi, Tayebeh. "Fabrication, microstructure and properties of new chalcogenide thin films and characterization of functional compounds." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:738fb9cd-220c-434b-9a67-472e8ae9f230.

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Fe-chalcogenides are of great interest because they have the simplest structure in the Fe-based superconductors, and show low anisotropies, high critical fields and high current densities all of which make these compounds useful for understanding Fe-based superconductors, a new class of superconductors with unusual properties, both for fundamental physics and potential high-field applications. The main part of this thesis concentrates on the fabrication and characterization of FeySe1-xTex (Fe-11) thin films in order to link superconductivity and microstructure in this system. Since sputtering
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44

Blagrove, Marcus S. C. "Generation and characterization of Wolbachia transinfections and development of female-specific RIDL technology in Aedes albopictus." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:f70a1ce7-de90-4a40-8760-58db88e7a823.

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Aedes albopictus is an important vector of dengue and chikungunya viruses, and, over recent decades, has resisted traditional control strategies allowing it to spread from its native Southeast Asia throughout the world. In this thesis, two alternative control methods are assessed and developed: transinfection with the inherited bacteria Wolbachia, for population replacement with a refractory strain; and a genetic equivalent to the sterile insect technique, RIDL (Release of Insects carrying a Dominant Lethal), for population suppression. Wolbachia is a genus comprising maternally inherited intr
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Buehler, Tabitha Christi. "A Search for and Characterization of Young Stellar Objects in N206, An H II Complex in the Large Magellanic Cloud." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/3178.

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I have identified 51 young stellar object candidates in N206, an H II complex in the nearby Large Magellanic Cloud galaxy. Using archival images from the Spitzer Space Telescope, supplemented with other infrared and optical images, I located point sources in this region. I distinguished possible young stellar objects based on their spectral energy distributions, morphologies, and locations in color-magnitude space. I classified the young stellar object candidates based on their likelihood of being young stellar objects and based on their apparent evolutionary stages. The spatial distribution o
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Karia, Dimple. "Characterization of the interactions between the H3K4 demethylase JARID1A and the SCL-nucleated oncogenic DNA binding complex." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:e2b330da-28ab-462f-a7bf-c78a85dd6696.

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Transcriptional regulation is of key importance to cellular processes such as development and differentiation, and it is dependent on the accessibility of DNA in the chromatin. Methylation and demethylation of histones alter properties of nucleosomes, thereby changing the accessibility of DNA. For many years, histone tail methylation was considered to be irreversible but in the last decade two families of histone demethylases were discovered, lysine specific demethylase 1 (LSD1) and Jumonji C (JMJC) demethylases. The work presented in this thesis focuses on the chromatin remodeling protein JAR
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Motnenko, Anna. "Characterization of UHRF2 (RNF107) as a novel sensor for DNA ICLs in the Fanconi Anemia pathway." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:019dffd3-cb3f-42dd-85b9-38eba5c554a9.

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The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA helix. An initial and essential stage in the repair process is the detection of the ICL. In a previous study, UHRF1 was identified as an ICL sensor in humans, it was shown that downstream repair factors were not recruited normally to the ICL in the absence of UHRF1. However, the mechanism underlying this process was unknown. Here, we report the identification of UHRF2, a paralogue of UHRF1, as an ICL sensor protein. We show that UHRF2 cooperates with UHRF1, to en
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48

Fu, Josephine K. Y. "Functional characterization of the teleost multiple tissue (tmt) opsin family and their role in light detection." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:39bc18bb-16cb-4549-94cd-5f872daafe7e.

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In addition to a central circadian clock in the suprachiasmatic nucleus (SCN), zebrafish (Danio rerio) have local clock systems in their peripheral tissues. These peripheral tissues express a complement of clock genes that can be synchronized with the 24 h light/dark cycle and thus may be entrained by light. To date, teleost multiple tissue (tmt) opsin identified from Fugu rubripes and Danio rerio is the only opsin that has been proposed as a candidate to mediate this cellular photoentrainment (Moutsaki et al., 2003). Here we report the discovery of a multigene family of tmt opsins found not o
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49

Walker, Paul Andreas. "Laser wakefield acceleration of electrons to GeV energies and temporal laser pulse compression characterization in a capillary discharge waveguide." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:e347422e-b097-4128-8733-f3686cc452fe.

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This thesis presents results from three strands of experimental work aimed towards establishing more reproducible, higher energy, and more accurately measured electron beams generated by a laser-driven plasma accelerator. The first experiment calibrated two types of detector frequently used to measure the bunch charge in laser wakefield accelerator experiments, namely scintillating screens and image plates. The experiments undertaken at the DAFNE beam test facility in Frascati, Italy, confirmed that the fluorescence signal from Kodak Lanex Regular screens varies linearly with the charge densit
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Baranovic, Jelena. "Structural and functional characterization of reconstituted alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors." Thesis, University of Oxford, 2011. https://ora.ox.ac.uk/objects/uuid:008f579f-828a-4792-8a2c-d2beffda458d.

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This thesis describes a novel reconstitution of &alpha;-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) for the purposes of structural characterization by atomic force microscopy (AFM) and functional characterization by electrical recordings of lipid bilayers. AMPARs are glutamate gated ion channels, ubiquitous in the vertebrate central nervous system where they mediate fast excitatory neurotransmission. In a healthy brain, AMPARs are involved in memory formation and learning and their dysfunction has been related to numerous neurological disorders such as Alzheimer's di
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