Thematische Bibliographien / Orchestrace release procesu

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Auswahl der wissenschaftlichen Literatur zum Thema „Orchestrace release procesu“

Autor: Grafiati

Veröffentlicht am 28. Juni 2021

Zuletzt aktualisiert am 29. Juli 2025

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Zeitschriftenartikel zum Thema "Orchestrace release procesu"

Panicucci, Chiara, Lizzia Raffaghello, Santina Bruzzone, et al. "eATP/P2X7R Axis: An Orchestrated Pathway Triggering Inflammasome Activation in Muscle Diseases." International Journal of Molecular Sciences 21, no. 17 (2020): 5963. http://dx.doi.org/10.3390/ijms21175963.

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In muscle ATP is primarily known for its function as an energy source and as a mediator of the “excitation-transcription” process, which guarantees muscle plasticity in response to environmental stimuli. When quickly released in massive concentrations in the extracellular space as in presence of muscle membrane damage, ATP acts as a damage-associated molecular pattern molecule (DAMP). In experimental murine models of muscular dystrophies characterized by membrane instability, blockade of eATP/P2X7 receptor (R) purinergic signaling delayed the progression of the dystrophic phenotype dampening t

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Sepsi, Adél, and Trude Schwarzacher. "Chromosome–nuclear envelope tethering – a process that orchestrates homologue pairing during plant meiosis?" Journal of Cell Science 133, no. 15 (2020): jcs243667. http://dx.doi.org/10.1242/jcs.243667.

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ABSTRACTDuring prophase I of meiosis, homologous chromosomes pair, synapse and exchange their genetic material through reciprocal homologous recombination, a phenomenon essential for faithful chromosome segregation. Partial sequence identity between non-homologous and heterologous chromosomes can also lead to recombination (ectopic recombination), a highly deleterious process that rapidly compromises genome integrity. To avoid ectopic exchange, homology recognition must be extended from the narrow position of a crossover-competent double-strand break to the entire chromosome. Here, we review a

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Zehorai, Eldar, Tamar Gross Lev, Elee Shimshoni, et al. "Enhancing uterine receptivity for embryo implantation through controlled collagenase intervention." Life Science Alliance 7, no. 10 (2024): e202402656. http://dx.doi.org/10.26508/lsa.202402656.

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Ineffective endometrial matrix remodeling, a key factor in infertility, impedes embryo implantation in the uterine wall. Our study reveals the cellular and molecular impact of human collagenase-1 administration in mouse uteri, demonstrating enhanced embryo implantation rates. Collagenase-1 promotes remodeling of the endometrial ECM, degrading collagen fibers and proteoglycans. This process releases matrix-bound bioactive factors (e.g., VEGF, decorin), facilitating vascular permeability and angiogenesis. Collagenase-1 elevates embryo implantation regulators, including NK cell infiltration and t

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Sprankel, Lasse, Margot P. Scheffer, Sina Manger, Utz H. Ermel, and Achilleas S. Frangakis. "Cryo-electron tomography reveals the binding and release states of the major adhesion complex from Mycoplasma genitalium." PLOS Pathogens 19, no. 11 (2023): e1011761. http://dx.doi.org/10.1371/journal.ppat.1011761.

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The nap particle is an immunogenic surface adhesion complex from Mycoplasma genitalium. It is essential for motility and responsible for binding sialylated oligosaccharides on the surface of the host cell. The nap particle is composed of two P140-P110 heterodimers, the structure of which was recently solved. However, the interpretation of the mechanism by which the mycoplasma cells orchestrate adhesion remained challenging. Here, we provide cryo-electron tomography structures at ~11 Å resolution, which allow for the distinction between the bound and released state of the nap particle, displayi

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Miricescu, Daniela, Silviu Constantin Badoiu, Iulia-Ioana Stanescu-Spinu, Alexandra Ripszky Totan, Constantin Stefani, and Maria Greabu. "Growth Factors, Reactive Oxygen Species, and Metformin—Promoters of the Wound Healing Process in Burns?" International Journal of Molecular Sciences 22, no. 17 (2021): 9512. http://dx.doi.org/10.3390/ijms22179512.

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Burns can be caused by various factors and have an increased risk of infection that can seriously delay the wound healing process. Chronic wounds caused by burns represent a major health problem. Wound healing is a complex process, orchestrated by cytokines, growth factors, prostaglandins, free radicals, clotting factors, and nitric oxide. Growth factors released during this process are involved in cell growth, proliferation, migration, and differentiation. Reactive oxygen species are released in acute and chronic burn injuries and play key roles in healing and regeneration. The main aim of th

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Bokman, Eduard, Ido Padro Kalij, and Alon Zaslaver. "Aberrant Positions of the Chemosensory Neurons in the Neurotransmitter-Release Mutant unc-13." International Journal of Molecular Sciences 25, no. 23 (2024): 12956. https://doi.org/10.3390/ijms252312956.

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Secretion of neurotransmitter- and neuropeptide-containing vesicles is a regulated process orchestrated by multiple proteins. Of these, mutants, defective in the unc-13 and unc-31 genes, responsible for neurotransmitter and neuropeptide release, respectively, are routinely used to elucidate neural and circuitry functions. While these mutants result in severe functional deficits, their neuroanatomy is assumed to be intact. Here, using C. elegans as the model animal system, we find that the head sensory neurons show aberrant positional layout in neurotransmitter (unc-13), but not in neuropeptide

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Nanbo, Asuka. "Current Insights into the Maturation of Epstein–Barr Virus Particles." Microorganisms 12, no. 4 (2024): 806. http://dx.doi.org/10.3390/microorganisms12040806.

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The three subfamilies of herpesviruses (alphaherpesviruses, betaherpesviruses, and gammaherpesviruses) appear to share a unique mechanism for the maturation and egress of virions, mediated by several budding and fusion processes of various organelle membranes during replication, which prevents cellular membrane disruption. Newly synthesized viral DNA is packaged into capsids within the nucleus, which are subsequently released into the cytoplasm via sequential fusion (primary envelopment) and budding through the inner and outer nuclear membranes. Maturation concludes with tegumentation and the

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Porcu, Cristiana, Gabriella Dobrowolny, and Bianca Maria Scicchitano. "Exploring the Role of Extracellular Vesicles in Skeletal Muscle Regeneration." International Journal of Molecular Sciences 25, no. 11 (2024): 5811. http://dx.doi.org/10.3390/ijms25115811.

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Skeletal muscle regeneration entails a multifaceted process marked by distinct phases, encompassing inflammation, regeneration, and remodeling. The coordination of these phases hinges upon precise intercellular communication orchestrated by diverse cell types and signaling molecules. Recent focus has turned towards extracellular vesicles (EVs), particularly small EVs, as pivotal mediators facilitating intercellular communication throughout muscle regeneration. Notably, injured muscle provokes the release of EVs originating from myofibers and various cell types, including mesenchymal stem cells

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Linnemann, Caren, Filiz Sahin, Yangmengfan Chen, et al. "NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields." International Journal of Molecular Sciences 24, no. 19 (2023): 14629. http://dx.doi.org/10.3390/ijms241914629.

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Fracture-healing is a highly complex and timely orchestrated process. Non-healing fractures are still a major clinical problem and treatment remains difficult. A 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) was identified as non-invasive adjunct therapy supporting bone-healing by inducing reactive oxygen species (ROS) and Ca2+-influx. However, ROS and Ca2+-influx may stimulate neutrophils, the first cells arriving at the wounded site, to excessively form neutrophil extracellular traps (NETs), which negatively affects the healing process. Thus, this study aimed to evalu

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Maag, Henning, Daniel J. Lemcke, and Johannes M. Wahl. "Ring opening of photogenerated azetidinols as a strategy for the synthesis of aminodioxolanes." Beilstein Journal of Organic Chemistry 20 (July 19, 2024): 1671–76. http://dx.doi.org/10.3762/bjoc.20.148.

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α-Aminoacetophenones are identified as promising building blocks for the synthesis of highly substituted dioxolanes. The presented strategy is founded on the build and release of molecular strain and achieves a formal transposition of a methyl group. During light irradiation, 3-phenylazetidinols are forged as reaction intermediates, which readily undergo ring opening upon the addition of electron-deficient ketones or boronic acids. Key to the successful development of this two-step process is the identification of a benzhydryl-protecting group, which orchestrates the photochemical Norrish–Yang

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Dissertationen zum Thema "Orchestrace release procesu"

Víšek, Jakub. "Hromadná orchestrácia v multirepo CI/CD prostrediach." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2021. http://www.nusl.cz/ntk/nusl-445562.

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Multirepo model přístupu ke správě a verzování zdrojového kódu, jež zahrnuje použití mnoha oddělených repozitářů verzovacích systémů, je poslední dobou často zmiňován v odborné literatuře. Jednou z jeho nevýhod je množství zdlouhavých, nezajímavých a repetitivních úkonů, které je nutno provádět při hromadných operacích tvořících transakce napříč těmito repozitáři. Multirepo repozitáře navíc umožňují využití široké škály technologií, což jen umocňuje riziko lidské chyby, ke které při ručně prováděných hromadných operacích může dojít. V rámci této práce je navrženo, implementováno a otestováno ř

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Buchteile zum Thema "Orchestrace release procesu"

Shah, Harsh, Nehareeka Dan, and Parth Pandya. "MAMMALIAN KISSPEPTIN AND PUBERTY: MECHANISM, DETECTION AND RECENT ADVANCEMENTS." In Futuristic Trends in Biotechnology Volume 3 Book 3. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bfbt3p2ch4.

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This study digs into the complexities of pubertal onset, a critical stage that includes sexual maturation, growth, and the development of secondary sexual features. The highly controlled process involves the Hypothalamic-Pituitary-Gonadal (HPG) axis, which orchestrates pubertal initiation via hormones, neuropeptides, and neurotransmitters such as Kisspeptin. Kisspeptin's involvement in GnRH release and its complex regulation by estrogen, Neuropeptide Y, and miRNAs are investigated. In this intricate network, dysregulation can result in delayed or premature puberty. The work emphasizes the impo

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Carvalho, Fabiana Rabe, Débora Familiar-Macedo, and Andrea Alice Silva. "Mitochondrial DNA Role in Zika Virus Infection." In Mitochondrial DNA and the Immuno-inflammatory Response: New Frontiers to Control Specific Microbial Diseases. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815051698122030009.

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Zika virus (ZIKV) is a member of the Flavivirus family. ZIKV infection ranges from asymptomatic to a mild disease in adults. However, in 2015, ZIKV infection became a public health emergency in the Americas associated with neurological alterations such as Guillain-Barré syndrome (GBS) in adults and congenital zika syndrome (CZS). By blocking type I IFN interferon signaling pathways, ZIKV evades the immune system and infects cells expressing the T cell immunoglobulin mucin domain-1 (TIM-1) and TAM (Tyro3, AXL, and Mer) receptors, such as neural progenitor cells. Moreover, ZIKV seems to orchestr

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Konferenzberichte zum Thema "Orchestrace release procesu"

KIM, JANETTE. "Rules of the Game: Tools for Governing Climate Justice." In 2021 AIA/ACSA Intersections Research Conference. ACSA Press, 2021. http://dx.doi.org/10.35483/acsa.aia.inter.21.20.

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Public engagement in climate adaptation planning is often described as a matter of urgency. Global, atmospheric change indeed amplifies the need to build trust, transparency, and consensus. However, rushing to action can preclude a deeper interrogation of the very political and economic systems that framed climate insecurity in the first place. This paper reflects on a public decision-making tool that navigates this tension between pragmatic action and structural reform. In It Together is a tabletop board game that engages urban stakeholders in a probing deliberative process over sea level ris

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