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Zeitschriftenartikel zum Thema „Pa Fox Chase“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 29. Juli 2025

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1

&NA;. "Fox Chase Cancer Center, Philadelphia, PA, USA." Melanoma Research 3, no. 1 (1993): 16. http://dx.doi.org/10.1097/00008390-199303000-00050.

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Mason, Bernice. "Abstract A002: Community outreach." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): A002. http://dx.doi.org/10.1158/1538-7755.disp22-a002.

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Abstract Sista's Daughters Inc. Mission Statement:Sista's Daughters Inc. is a community Cancer Outreach Organization.Our mission is to support families through challenges associated with Cancer.Our focus is Breast Cancer. However, we have incorporated Kidney and Prostate Cancer due to the impact on the lives of underservered and unrepresented communities. SDI was started to lower health resource disparties, increase welliness and create equal Cancer's resource accessibility for impoverished communities.Services:Our organization sponsors Community Cancer Health Fairs which included blood screen

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Zhu, Lin, Ellen J. Kim, Steven Zhu, et al. "Abstract PR010: Evaluating a bidirectional academic–community partnership with multiple racial/ethnic communities for cancer prevention initiatives and cancer health disparities research." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): PR010. http://dx.doi.org/10.1158/1538-7755.disp22-pr010.

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Abstract Background: The Temple University Fox Chase Cancer Center and Hunter College Cancer Health Disparity Partnership (TUFCCC/HC Cancer Partnership) is a comprehensive collaborative cancer health research infrastructure in Pennsylvania, New Jersey, and New York City (PNN) Region. Its goals are to enhance equity in cancer health through rigorous and sustainable cancer research, train the next generation of researchers, and establish community outreach programs. Establishing and strengthening a bidirectional academic-community partnership is a key component of this partnership. While such co

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Krzizike, Daniel D., Margie L. Clapper, and Andrew J. Andrews. "Abstract 2345: Specificity of catechol-O-methyltransferase (COMT) for hydroxyestrogens favors 2-OHEs over 4-OHEs." Cancer Research 82, no. 12_Supplement (2022): 2345. http://dx.doi.org/10.1158/1538-7445.am2022-2345.

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Abstract The contribution of estrogen receptor-mediated signaling to cancer progression and metastasis has been well documented. However, much less attention has been given to the role of estrogen metabolism in carcinogenesis. Parent estrogens are metabolized to 2- and 4-hydroxyestrogens (2-OHEs and 4-OHEs) that can retain their estrogenic activity, form reactive quinones that cause DNA damage, or become inactivated primarily by the rate-limiting conjugation enzyme catechol-O-methyltransferase (COMT). The ability of 4-OHEs to induce genomic instability and the malignant transformation of human

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Saini, Sharanjot, and Amritha Sreekumar. "Abstract 6574: Plant-derived vesicles as potential therapy for neuroendocrine prostate cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 6574. https://doi.org/10.1158/1538-7445.am2025-6574.

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Abstract Background: Neuroendocrine prostate cancer (NEPC) is a highly aggressive lethal variant of prostate cancer (PCa) with extremely poor survival times (&lt;1 year). Clinical management of NEPC is currently challenging as there are limited treatment options for these patients. These patients are treated with platinum-based chemotherapy that is associated with toxicity and relapses. This emphasizes the need for newer, more effective therapeutic interventions against this challenging disease. The overall objective of this study was to develop an effective, non-toxic, cheap yet scalable

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Fleisher, Linda, Cassidy Kenny, Shayna Yeates Yeates, et al. "Abstract B007: mychoiceTM User-Testing – Insights from diverse cancer patients." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): B007. http://dx.doi.org/10.1158/1538-7755.disp22-b007.

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Abstract (A) Although clinical trials (CTs) aim to establish new strategies for reducing cancer morbidity and mortality, participation remains suboptimal, especially for racial and ethnic minorities, and few studies have evaluated tailored communication tools to address barriers/facilitators to CT participation across diverse groups.(B) mychoiceTM is a novel, culturally tailored online CT education tool designed to foster shared decision making between patients (pts) and their providers. The mychoiceTM tool was developed over 5 years utilizing community engagement, perceptual mapping, a clinic

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Brecher, Alison C., Cassidy Kenny, Donna Edmondson, Allison Zambon, Linda Fleisher, and Hossein Borghaei. "Abstract B002: Addressing disparities and barriers to care between Black and White cancer patients who use tobacco." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): B002. http://dx.doi.org/10.1158/1538-7755.disp22-b002.

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Abstract Purpose of the study: Smoking is detrimental to treatment outcomes for both smoking and non-smoking-related cancers, and tobacco cessation is an integral part of comprehensive cancer care. Through the support of a competitive grant funded by the NCI’s Cancer Center Cessation Initiative, Fox Chase Cancer Center (FCCC) optimized their Tobacco Treatment Program (TTP). Within the first year of optimization, TTP’s reach increased tenfold by implementing an automated tobacco registry through a nightly EMR feed that proactively reaches all new cancer patients who have used tobacco in the las

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Bodor, J. Nicholas, Joseph Treat, Daniel D. Krzizike, et al. "Abstract 2696: Catechol estrogen profiles of patients with EGFR- and ALK-positive non-small cell lung cancer (NSCLC)." Cancer Research 82, no. 12_Supplement (2022): 2696. http://dx.doi.org/10.1158/1538-7445.am2022-2696.

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Abstract Prior research from this group indicates that the human lung extensively metabolizes parent estrogens to reactive catechols. Estrone (E1) and estradiol (E2) are converted to the putative carcinogens, 4-hydroxyestrone (4-OHE1) and 4-hydroxyestradiol (4-OHE2), by cytochrome P450 1B1 (CYP1B1). In contrast, CYP1A1 metabolizes parent estrogens to 2-OHE1 and 2-OHE2, which may ultimately be converted to anti-proliferative derivatives. Our previous data strongly indicate that 4-OHEs contribute to lung tumorigenesis. However, their role in oncogene-driven NSCLC has not been investigated. The g

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Truehart, Jade A., Elisabeth Russell McKenzie, Cicely Johnson, Grace X. Ma, SJ Dodd, and Lin Zhu. "Abstract B095: Evaluating the research experiences and outcomes of pre-pilot and pilot awardees of a U54 regional cancer partnership: Success, challenges, and solutions." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): B095. http://dx.doi.org/10.1158/1538-7755.disp24-b095.

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Abstract Purpose: The Synergistic Partnership for Enhancing Equity in Cancer Health (SPEECH) is a regional, comprehensive cancer health disparity initiative jointly led by Temple University/Fox Chase Cancer Center and Hunter College (TUFCCC/HC). This partnership is supported by a U54 grant from the National Cancer Institute. In this study, we present the successes of the Pre-Pilot and Pilot Projects funded by the U54 Partnership Matched Fund. Additionally, we discuss the challenges encountered in the award process and propose solutions to enhance this process for current and future recipients.

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Liu, Zhiqing E., Wenyue Lu, Evelyn T. González, et al. "Abstract B094: Building trust as the foundation for successful cancer awareness initiatives in underserved racial/ethnic minority communities." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): B094. http://dx.doi.org/10.1158/1538-7755.disp24-b094.

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Abstract Introduction: Racial and ethnic minorities often face disparities in cancer screening, leading to delayed diagnoses and poorer outcomes. Community-based participatory research (CBPR) presents inherent complexity due to the dynamic and multifaceted nature of the targeted communities. The Synergistic Partnership for Enhancing Equity in Cancer Health (SPEECH) is a regional, comprehensive cancer health disparity initiative jointly led by Temple University/Fox Chase Cancer Center and Hunter College (TUFCCC/HC). A key component of the SPEECH Partnership is to reduce cancer health disparitie

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Bodor, J. Nicholas, Rodrigo T. Macedo, Kristen Harvey, et al. "Abstract 1797: Impact of estrogen depletion using an aromatase inhibitor (AI) on EGFR-mutated non-small cell lung cancer (NSCLC) in a murine model." Cancer Research 83, no. 7_Supplement (2023): 1797. http://dx.doi.org/10.1158/1538-7445.am2023-1797.

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Abstract EGFR-mutated lung tumors respond poorly to checkpoint (PD-1/PD-L1) inhibitors. Resistance to such therapies has been attributed to the prototypic immunosuppressed “cold” tumor microenvironment (TME) of EGFR-mutated NSCLCs, which is characterized by low levels of tumor infiltrating lymphocytes. Growing evidence from breast cancer studies demonstrates the ability of 17β-estradiol to regulate several species of immune cells within an immunosuppressive TME. Furthermore, treatment of breast cancers with AIs or estrogen receptor antagonists promotes lymphocyte infiltration and enhances immu

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El-Deiry, Wafik S., Andrew George, Francesca Di Cristofano, et al. "Abstract 4185: Inclusive basic and advanced translational laboratory research competencies for research in cancer biology and therapeutics." Cancer Research 83, no. 7_Supplement (2023): 4185. http://dx.doi.org/10.1158/1538-7445.am2023-4185.

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Abstract Our Laboratory was established in 1994 at Univ. of Pennsylvania. Lab members demonstrated initial competencies by performing cell culture, western blots, immunofluorescence, and flow cytometry showing induction of p53/p21(WAF1) in cells treated with chemotherapy. Years later, our Laboratory of Translational Oncology & Experimental Cancer Therapeutics moved to Penn State Univ., Fox Chase Cancer Center/Temple Univ. and then Brown Univ. By 2020, with desire for inclusiveness (everyone succeeds), scientific rigor/reproducibility mandated by NIH, and as a training and mentoring activit

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Zhu, Lin, S. J. Dodd, Yuku Chen, et al. "Abstract A068: Educating the next generation of cancer researchers: Evaluation of a cancer research partnership training program." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): A068. http://dx.doi.org/10.1158/1538-7755.disp23-a068.

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Abstract Introduction: The underrepresentation of minorities in cancer research hampers efforts to address disparities among minority populations. To tackle this issue, early mentorship of emerging scientists from underrepresented communities is crucial. The Synergistic Partnership for Enhancing Equity in Cancer Health (SPEECH) is a collaboration between Temple University/Fox Chase Cancer Center, Hunter College (TUFCCC/HC), and funded by the National Cancer Institute. SPEECH aims to reduce cancer health disparities through research, community outreach, and support for underrepresented investig

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Kacem, Mariam Ben, Scott J. Bright, Broderick X. Turner, et al. "Abstract P2-06-01: Parp inhibition sensitizes brca deficient cancer cell lines and tumors to clinical x-ray and proton irradiation." Cancer Research 82, no. 4_Supplement (2022): P2–06–01—P2–06–01. http://dx.doi.org/10.1158/1538-7445.sabcs21-p2-06-01.

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Abstract Purpose Triple negative breast cancers (TNBC) are more often found among BRCA gene mutation carriers; even among non-mutation carriers, TNBCs are thought to carry a phenotype of BRCAness. Inhibitors of Poly(adenosine diphosphate-ribose) polymerase (PARPi) have improved survival outcomes for both advanced and early stage breast cancer associated with a BRCA mutation, as well as BRCA mutated ovarian and prostate cancers. Radiotherapy (RT) is a widely used treatment to locally control cancers, but it is unclear how different types of RT, including clinical x-rays and protons, interact wi

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Chakraborty, Anumita, Lauren Correia, Jill Hasler, et al. "Abstract P3-01-05: The Effect of Individual and Neighborhood-level Socioeconomic Disparities in Advanced and Early-Onset Female Breast Cancer." Clinical Cancer Research 31, no. 12_Supplement (2025): P3–01–05—P3–01–05. https://doi.org/10.1158/1557-3265.sabcs24-p3-01-05.

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Abstract Background: Race is a significant factor in the diagnosis and outcomes of breast cancer (BC); Black women are diagnosed with more aggressive disease, and have higher mortality from BC compared to White women. Race may be a surrogate for other social determinants of health (SDOH), which may explain observed disparities. Further study is needed to assess the effect of all 5 domains of SDOH (education access and quality, health care access and quality, neighborhood and built environment, social and community context, and economic stability) on BC. In the absence of individual-level infor

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Carroll, P. "Failure pattern implications following external beam irradiation of prostate cancer: long-term follow-up and indications of cure. Alexandra L. Hanlon, Ph.D.,a,b Gerald E. Hanks, M.D.,b Departments of aRadiation Oncology and bBiostatistics, Fox Chase Cancer Center, Philadelphia, PA, USA.Clinical utility of the percentage of positive prostate biopsies in defining biochemical outcome after radical prostatectomy for patients with clinically localized prostate cancer. Anthony V. D'Amico, Richard Whittington, S. Bruce Malkowicz, Delray Schultz, Julia Fondurulia, Ming-Hui Chen, John E. Tomaszewski, Andrew A. Renshaw, Alan Wein, and Jerome P. Richie, Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA 02215, USA.Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Prostate Cancer Trialists' Collaborative Group.Implications of stage-specific survival rates in assessing recent declines in prostate cancer mortality rates. Robert E. Tarone, Kenneth C. Chu, and Otis W. Brawley, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA." Urologic Oncology 6, no. 3 (2001): 123–24. http://dx.doi.org/10.1016/s1078-1439(01)00119-3.

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Smith, Thomas J., Louise M. Ryan, Harold O. Douglass, et al. "Combined chemoradiotherapy vs. radiotherapy alone for early stage squamous cell carcinoma of the esophagus: a study of the eastern cooperative oncology group 11Other participating institutions: Albany Medical College, Albany, NY (CA 06594); Albert Einstein College of Medicine, Bronx, NY (CA 14958); University of California-Irvine, Orange, CA; Case Western Reserve University, Cleveland, OH (CA 14548); Chicago Medical School, Chicago, IL (CA 14144); Colorado Cancer Research Program, Denver, CO; Downstate Medical Center, Brooklyn, NY; University of Florida-Gainesville, Gainesville, FL; Fox Chase Cancer Center, Philadelphia, PA (CA 18281); Indiana University Medical Center, Indianapolis, IN (CA 49883); Medical College of Ohio, Toledo, OH; University of Medicine and Dentistry of New Jersey, Newark, NJ; University of Minnesota, Minneapolis, MN (CA 20365); New York University Medical Center, New York, NY (CA 16395); Newark Beth Israel Medical Center, Newark, NJ; Rush-Presbyterian-St. Luke’s Medical Center, Chicago, IL (CA 25988); University of Pretoria, Pretoria, South Africa (CA 21692); Natalie Warren Bryant Cancer Center, Tulsa, OK; Vermont Regional Cancer Center, Burlington, VT." International Journal of Radiation Oncology*Biology*Physics 42, no. 2 (1998): 269–76. http://dx.doi.org/10.1016/s0360-3016(98)00232-6.

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"First person – Jacqueline Simonet." Biology Open 9, no. 7 (2020). http://dx.doi.org/10.1242/bio.054718.

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ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Jacqueline Simonet is first author on ‘CTP synthase polymerization in germline cells of the developing Drosophila egg supports egg production’, published in BiO. Jacqueline conducted the research described in this article while a postdoctoral research associate in Jeffrey Peterson's lab at Fox Chase Cancer Center, Philadelphia, PA and is now a Visiting Assistant Professor at Arcadia University, PA,

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"Glutathione S-transferase expression in hepatitis B virus-associated human hepatocellular carcinogenesis Zhou, T., Evans, A.A., London, W.T., Xia, X., Zou, H., Shen, F.-M., Clapper, M.L. Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA Cancer Research 1997; 57 (13): 2749–2753." Hepatology Research 9, no. 1 (1997): 64. http://dx.doi.org/10.1016/s1386-6346(97)90027-9.

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