Auswahl der wissenschaftlichen Literatur zum Thema „Paget“

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Zeitschriftenartikel zum Thema "Paget":

1

CENGİZ, Fatma Pelin, Nazan EMİROĞLU, Dilek BIYIK ÖZKAYA, Zeynep TOSUNER, Özlem SU, Anıl GÜLSEL BAHALI, Pelin YILDIZ und Nahide ONSUN. „Extramammary Paget Disease: Case Report“. Turkiye Klinikleri Journal of Dermatology 26, Nr. 3 (2016): 160–63. http://dx.doi.org/10.5336/dermato.2015-48385.

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YAMAMOTO, Toshiyuki. „Paget disease.Three cases of mammary Paget disease.“ Skin Cancer 6, Nr. 3 (1991): 422–26. http://dx.doi.org/10.5227/skincancer.6.422.

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Brodner, W., R. Eyb und A. Engel. „Paget-Coxarthrose“. Zeitschrift für Orthopädie und ihre Grenzgebiete 132, Nr. 04 (18.03.2008): 295–99. http://dx.doi.org/10.1055/s-2008-1039977.

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Kitchen, Sheila. „Paget Error“. Physiotherapy 80, Nr. 7 (Juli 1994): 498. http://dx.doi.org/10.1016/s0031-9406(10)60833-4.

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Blazak, John Kenneth, und Paul Thomas. „Paget Disease“. Clinical Nuclear Medicine 41, Nr. 9 (September 2016): 699–700. http://dx.doi.org/10.1097/rlu.0000000000001296.

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THIERY M. „James Paget (1814-1899) en de ziekte van Paget“. Tijdschrift voor Geneeskunde 63, Nr. 9 (01.01.2007): 436–37. http://dx.doi.org/10.2143/tvg.63.09.2000083.

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SHIMIZU, Michio. „Origin of Paget's cells in Paget's disease“. Skin Cancer 26, Nr. 1 (2011): 21–27. http://dx.doi.org/10.5227/skincancer.26.21.

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Jay, Venita. „Sir James Paget“. Archives of Pathology & Laboratory Medicine 123, Nr. 11 (01.11.1999): 995. http://dx.doi.org/10.5858/1999-123-0995-sjp.

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&NA;. „Paget??s disease“. Inpharma Weekly &NA;, Nr. 1123 (Februar 1998): 3. http://dx.doi.org/10.2165/00128413-199811230-00005.

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Donoughe, John Scott. „Paget-Schroetter Syndrome“. JBJS Journal of Orthopaedics for Physician Assistants 5, Nr. 4 (Oktober 2017): e28. http://dx.doi.org/10.2106/jbjs.jopa.17.00025.

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Dissertationen zum Thema "Paget":

1

Nespeca, Daria [Verfasser]. „CCR10 und Morbus Paget / Daria Nespeca“. Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2020. http://d-nb.info/1223705250/34.

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Cammarata, Angela. „Valutazioni fisiopatologiche del Morbo di Paget“. Thesis, Universita' degli Studi di Catania, 2011. http://hdl.handle.net/10761/327.

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Il morbo di Paget e' una forma tumorale, a lenta crescita, localizzata al capezzolo e piu' raramente in regione ano-genitale, perianale, ascellare o inguinale. Si tratta di un adenocarcinoma epiteliale, che si associa spesso ad un sottostante carcinoma in situ o un carcinoma invasivo della mammella e in caso di localizzazione extramammaria, ad un carcinoma sottostante. La malattia si localizza tipicamente al capezzolo o all'areola mammaria, monolateralmente, sotto forma di una piccola chiazza eritematosa essudante o di un semplice ispessimento cutaneo, a lenta estensione centrifuga, spesso accompagnata da prurito o dolore. Ci sono due teorie sull'istogenesi del Paget: La teoria epidermotropica sostiene che le cellule di Paget siano cellule da carcinoma duttale migrate per continuita' di un sottostante carcinoma dei dotti galattofori nella forma mammaria e dalle ghiandole del glande, del retto, della cervice e della vescica nelle forme extramammaria. La teoria della trasformazione in situ e' stata proposta per spiegare lo sviluppo di questa alterazione in pazienti che non hanno un carcinoma mammario sottostante. Nei pazienti in cui il tumore e' clinicamente e radiologicamente negativo, puo' essere studiato attraverso l'istochimica e l'immunoistochimica. Studi di istochimica mostrano che le cellule di Paget sono PAS positive nel 30% dei casi ed alcian blu positive nel 20% dei casi.
Mammary and extramammary Paget's disease are rare neoplasm of epidermis and mucosal epithelium. Due to their nonspecific and variable clinical view, they have differential diagnosis with eczema, melanoma, Bowen's disease, etc. The histogenesis of Paet's disease has been hotly debated, and only recently has epidermotropic theory become widely accepted. With the evolution of our understanding of breast cancer, it became apparent that the prognosis of Paget's disease was more a reflection of that of the underlying carcinoma, be it intraductal or infiltrating. The standanrd treatment of Paget's disease remains mastectomy with or without axillary dissection. In this are of breast-conserving surgery, however, there is much evidence to suggest that conservative treatment of Paget's disease of the breast is possible.
3

Arnautou, Jean-Pierre. „La maladie osseuse de Paget : étude paléopathologique“. Bordeaux 1, 2007. http://www.theses.fr/2007BOR13489.

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Après un rappel des principaux aspects de la maladie osseuse de Paget chez le vivant, les 148 cas anciens de cette affection publiés dans la littérature paléoanthropologique sont analysés et critiqués. L'étude de trois cas personnels et la révision du premier cas publié (Pales, 1929) fournissent les éléments d'une description précise des lésions de la maladie de Paget sur l'os sec ; pour la reconnaître, nous proposons une liste de critères, avec une cotation pour chacun d'entre eux, permettant d'envisager ce diagnostic. La maladie apparaît d'abord au Néolithique, sur le rivage nord de la Méditerranée ; elle se répand ensuite lentement en Europe, au nord et à l'ouest de l'Empire romain, avant de devenir beaucoup plus fréquente dans l'Angleterre médiévale. Sa dissémination dans le monde contemporain semble liée à l'émigration anglo-saxonne. Sa présence dans l'Amérique préhistorique est contestée. Le rôle du chien, en tant que vecteur d'un éventuel agent pathogène, est discuté.
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Pessayre, Hélène. „Contribution à l'étude de la maladie de Paget du mamelon : à propos de 20 observations“. Montpellier 1, 1989. http://www.theses.fr/1989MON11310.

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Morin, Ludovic. „Le traitement de la maladie osseuse de Paget par le tiludronate : effets cliniques et biologiques chez 14 malades“. Saint-Etienne, 1995. http://www.theses.fr/1995STET6205.

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Andrade, José Costa de [UNESP]. „Perfil imunoistoquímico do carcinoma de Paget da mama“. Universidade Estadual Paulista (UNESP), 2004. http://hdl.handle.net/11449/103714.

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Universidade Estadual Paulista (UNESP)
O objetivo deste trabalho foi estudar através do exame Imunoistoquimico, a correlação entre alguns fatores Anatomopatológicos (tipo histológico e grau nuclear) e alguns fatores biológicos (receptores hormonais de estrógeno e de progesterona, proteína c-erbB-2 e proteína p53, no carcinoma de Paget da mama, doença rara e especial. No período entre Janeiro de 1980 a Dezembro de 1998 foram tratados no Instituto Brasileiro de Controle do Câncer, 6.303 casos de câncer de mama, deste total 98 casos foram diagnosticados como carcinoma de Paget, cuja incidência foi de 1,55%. Estudamos retrospectivamente 60 casos, sendo que 38 deles foram excluídos da análise, devido a limitação e escassez da amostra no material disponível, a idade das pacientes variou entre 26 e 84 anos, com média de 55,4 anos, as informações clínicas e terapêuticas foram obtidas dos prontuários das pacientes considerando, idade na época do diagnóstico, tamanho do tumor quando palpável, estadiamento clínico, e o tipo de cirurgia realizada. As amostras de tecido mamário foram recuperadas dos arquivos do Departamento de Anatomia Patológica do I.B.C.C. / MATTOSINHO. Após a revisão histológica, realizada por dois patologistas os casos foram classificados em quatro grupos: Grupo A- Doença de Paget (forma pura) n = 09 Grupo B- Doença de Paget + neoplasia ductal “in situ”, n = 12 Grupo C- Doença de Paget, neoplasia ductal invasora, n = 30 Grupo D- Doença de Paget + neoplasia ductal “in situ”+ neoplasia ductal invasora, n = 09. Entre as variáveis anatomopatológicas, o grupo C prevaleceu com 30 casos (50%). O grau nuclear (GN-II) predominou com 45 casos (75%). Em relação as variáveis biológicas o receptor de estrógeno negativo predominou com 41 casos (68,3%), seguido pelo receptor de progesterona negativo com 40 casos (66,7%), podemos dizer que...
The objective of this paper was to study the immunohistochemical efects of Paget’s disease, a rare and special carcinoma of the breast, by correlating anatomopathological (histological and nuclear grade) and biological (estrogen and progesterone hormonal receptors, c-erbB-2 protein and p53 protein) factors. Between January 1980 and December 1998, 6303 cases of breast cancer were treated at the Brazilian Institute of Cancer Control; 98 of these were diagnosed with Paget’s carcinoma, an incidence of 1.55%. We retrospectively studied 60 of these cases; 38 were excluded due to lack of available sample material. Patient age varied between 26 and 84 years (mean 55.4), clinical and therapeutic information were obtained from patient’s medical records considering age at time of diagnosis, tumor size when palpable, clinical stage, and type of surgery performed. Samples of breast tissue were retrieved the Anatomical Pathology Department, I.B.C.C. / MATTOSINHO. After histological review, by two different pathologists, they were classified into four groups: Group A- Paget’s disease (pure form) n = 09 Group B- Paget’s disease + “in situ” duct neoplasia n = 12 Group C- Paget’s disease, invasive duct neoplasia n = 30 Group D- Paget’s disease + “in situ” duct neoplasia + invasive duct neoplasia n = 09.Invasive duct neoplasia was the most prevalent anatomopathological variable (Group C, n = 30, 50%). Nuclear grade (GNII) was found in 45 cases (75%). In relation to the biological variables, the negative estrogen receptor was predominant with 41 cases (68.3%), followed by the negative progesterone receptor with 40 cases (66.7%); this correlation had good concordance by the Kappa test. The c-erbB-2 protein was positive in 53 cases (88.3%) and p53 was negative in 47 cases (78.3%). From these results, we concluded that there was no statistical... (Complete abstract click electronic address below)
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Rossi, Karin Kneipp Costa. „Doença de Paget de mama : diagnostico e prognostico“. [s.n.], 2003. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313341.

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Orientadores: Cesar Cabello dos Santos, Marcelo Alvarenga
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
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Resumo: Objetivos: Calcular a frequência, descrever aspectos clínicos, mamográficos, e histopatológicos, assim como formas do tratamento cirúrgico e o prognóstico de pacientes com doença de Paget de mama. Sujeitos e método: Foi realizado um estudo descritivo analítico entre os anos de 1988 a 2002 em mulheres tratadas de câncer de mama no Centro de Atenção Integral à Saúde da Mulher da Universidade Estadual de Campinas. Foram calculados os valores de frequência da doença, descritas características epidemiológicas, do exame clínico, das mamografias, além de formas de tratamento cirúrgico e o prognóstico destas pacientes. Para a análise estatística foram calculados valores de frequência e descritas as porcentagens das categorias das variáveis estudadas. Foram utilizados os testes qui-quadrado, t'student e exato de Fisher para análise de associação de algumas variáveis. Para avaliar o prognóstico da doença foram realizadas curvas de sobrevivência pelo método de Kaplan Mayer analisadas pelo teste LogRank. Resultados: Foram observados 4.536 casos de câncer de mama, sendo que destes, 80 apresentavam doença de Paget de mama. Isto correspondeu no período estudado a uma frequência média de 1,76%. As pacientes assintomáticas em relação ao complexo aréolo-papilar corresponderam a 46% dos casos estudados. Encontraram-se alterações no complexo aréolo-papilar ao exame clínico em 63% das pacientes e estavam associadas a nódulos mamários em mais da metade. A mamografia falhou em diagnosticar os tumores mamários em 30% e em 64% não mostrou alterações no complexo aréolo-papilar. Todos os casos associaram-se com carcinomas mamários subjacentes. Mulheres com sintomas de alterações de complexo aréolo-papilar apresentaram 44% de carcinoma in situ e 66% de axila negativa, sendo que entre aquelas sem sintomas, a freqüência foi de 3% e 34%, respectivamente (p=0,011 e p=0,000). A sobrevida global foi significativamente maior nas pacientes com sintomas no complexo aréolo-papilar do que naquelas sem sintomas (p=0,031). A presença de nodulação ao exame clínico associou-se à presença de carcinoma invasor em 89% e de axila comprometida em 61%, enquanto que a ausência de nodulação associou-se com 38% e 19% respectivamente (p=0,000). As recidivas locais ocorreram em 38% (5/13) das pacientes submetidas a quadrantectomias e em 7,7% (5/65) das mastectomizadas (p=0,002). Conclusão: A doença de Paget de mama foi uma entidade rara. Em quase metade das pacientes não manifestou sintomas no complexo aréolo-papilar. Grande parte das pacientes apresentou ao exame clínico alterações de complexo aréolo-papilar associadas a nodulações nas mamas, sendo que o achado clínico de nódulo esteve associado à doença mais avançada. O exame mamográfico foi inadequado para avaliação do complexo aréolo-papilar. As pacientes submetidas às quadrantectomias apresentaram alta taxa de recorrência local. Os exames clínicos e mamográficos não foram capazes de prever as recorrências locais no grupo das quadrantectomia. As pacientes com queixa de alterações de papila tiveram melhor sobrevida
Abstract: Objetive: To calculate the frequency, and describe the clinical, mamographics and the histopatologic aspects of Paget disease of the breast. Futhermore evalute the surgical treatment and the prognosis of these patients. Method: It was done a descriptive study in breast cancer women attended at Integral Women Attention Center (CAISM) of the University of Campinas between 1988 and 2002. It was calculated the disease frequency and It was performed the associated analyses of some clinical, variables with the Chi-square , t'student and e the FISHER's exat test. It was done Kaplan Mayer curves and LogRank analyse to evaluet the prognosis of the Paget disease of the breast with regards to some aspects. Results: The mean frequency was 1.76%. 46% of patients was assimptomatic about the nipple-areola complex. 63% presented nipple-areola complex disturbed associated to breast lumps generally. The mammography failed the breast tumor associated diagnosis in 30% and in 64% the nipple-areola complex was wrongly normal. All of the cases was associated to breast carcinomas beneth. The nipple-areola complex complains was associated to 44% of in situ ductal carcinomas and 66% of negative axila findings, while the noncomplains women with 3% and 34% respectivelly (p=0.011 and p=0.000). The women with nipple-areola complex complains were associated to better survival compared to the non-complains ones (p=0.031). The breast finding of lump was associated to 89% of invasive breast cancer and 61% of positive axilar node, compared to the non-breast lump patients with 38% and 19% respectivelly (p=0.000). The quandrantectomies was involved to 39% of local relapses compared to the mastectomies with 7.7% (p=0.002). Conclusion: The Paget disease of the breast was rare one. It was not observed nipple-areola complex symptoms in almost half of patients. In the majority of patients was observed finding of nipple-areola complex at clinical breast exam associated to breat lumpness. These clinical finding of breast lump was associated to more advanced breast cancer. The mammography was inappropiate to evaluate the nipple-areola complex. The patients submitted to the quandrantectomies presented high local relapse rate. The clinical and mammographic evaluation were inappropriate to identify the risk of local relapse in the conservative group. The women with nipple-areola complex complains was associated to better survival
Mestrado
Tocoginecologia
Mestre em Tocoginecologia
8

Andrade, José Costa de. „Perfil imunoistoquímico do carcinoma de Paget da mama /“. Botucatu : [s.n.], 2004. http://hdl.handle.net/11449/103714.

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Orientador: Laurival Antonio De Luca
Resumo: O objetivo deste trabalho foi estudar através do exame Imunoistoquimico, a correlação entre alguns fatores Anatomopatológicos (tipo histológico e grau nuclear) e alguns fatores biológicos (receptores hormonais de estrógeno e de progesterona, proteína c-erbB-2 e proteína p53, no carcinoma de Paget da mama, doença rara e especial. No período entre Janeiro de 1980 a Dezembro de 1998 foram tratados no Instituto Brasileiro de Controle do Câncer, 6.303 casos de câncer de mama, deste total 98 casos foram diagnosticados como carcinoma de Paget, cuja incidência foi de 1,55%. Estudamos retrospectivamente 60 casos, sendo que 38 deles foram excluídos da análise, devido a limitação e escassez da amostra no material disponível, a idade das pacientes variou entre 26 e 84 anos, com média de 55,4 anos, as informações clínicas e terapêuticas foram obtidas dos prontuários das pacientes considerando, idade na época do diagnóstico, tamanho do tumor quando palpável, estadiamento clínico, e o tipo de cirurgia realizada. As amostras de tecido mamário foram recuperadas dos arquivos do Departamento de Anatomia Patológica do I.B.C.C. / MATTOSINHO. Após a revisão histológica, realizada por dois patologistas os casos foram classificados em quatro grupos: Grupo A- Doença de Paget (forma pura) n = 09 Grupo B- Doença de Paget + neoplasia ductal "in situ", n = 12 Grupo C- Doença de Paget, neoplasia ductal invasora, n = 30 Grupo D- Doença de Paget + neoplasia ductal "in situ"+ neoplasia ductal invasora, n = 09. Entre as variáveis anatomopatológicas, o grupo C prevaleceu com 30 casos (50%). O grau nuclear (GN-II) predominou com 45 casos (75%). Em relação as variáveis biológicas o receptor de estrógeno negativo predominou com 41 casos (68,3%), seguido pelo receptor de progesterona negativo com 40 casos (66,7%), podemos dizer que... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The objective of this paper was to study the immunohistochemical efects of Paget's disease, a rare and special carcinoma of the breast, by correlating anatomopathological (histological and nuclear grade) and biological (estrogen and progesterone hormonal receptors, c-erbB-2 protein and p53 protein) factors. Between January 1980 and December 1998, 6303 cases of breast cancer were treated at the Brazilian Institute of Cancer Control; 98 of these were diagnosed with Paget's carcinoma, an incidence of 1.55%. We retrospectively studied 60 of these cases; 38 were excluded due to lack of available sample material. Patient age varied between 26 and 84 years (mean 55.4), clinical and therapeutic information were obtained from patient's medical records considering age at time of diagnosis, tumor size when palpable, clinical stage, and type of surgery performed. Samples of breast tissue were retrieved the Anatomical Pathology Department, I.B.C.C. / MATTOSINHO. After histological review, by two different pathologists, they were classified into four groups: Group A- Paget's disease (pure form) n = 09 Group B- Paget's disease + "in situ" duct neoplasia n = 12 Group C- Paget's disease, invasive duct neoplasia n = 30 Group D- Paget's disease + "in situ" duct neoplasia + invasive duct neoplasia n = 09.Invasive duct neoplasia was the most prevalent anatomopathological variable (Group C, n = 30, 50%). Nuclear grade (GNII) was found in 45 cases (75%). In relation to the biological variables, the negative estrogen receptor was predominant with 41 cases (68.3%), followed by the negative progesterone receptor with 40 cases (66.7%); this correlation had good concordance by the Kappa test. The c-erbB-2 protein was positive in 53 cases (88.3%) and p53 was negative in 47 cases (78.3%). From these results, we concluded that there was no statistical... (Complete abstract click electronic address below)
Doutor
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GRANEL, JEAN. „Maladie de paget de l'os traitee par pamidronate“. Toulouse 3, 1994. http://www.theses.fr/1994TOU31558.

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Presani, Joël. „La maladie de Paget et son traitement par le clodronate“. Bordeaux 2, 1992. http://www.theses.fr/1992BOR2P093.

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Bücher zum Thema "Paget":

1

Petty, Elizabeth. Jonathan Paget, MD. Bath, England: Chivers Press, 1990.

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Petty, Elizabeth. Jonathan Paget, MD. London: Mills & Boon, 1985.

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Society, Paget Gorman, und Invalid Children's Aid Nationwide, Hrsg. Paget Gorman signed speech. Oxford: Paget Gorman Society, ICAN, 1987.

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White, David L. Bermuda's architectural heritage: Paget. Hamilton: Bermuda National Trust, 2010.

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Smith, Frank. Candles for the dead. New York: St. Martin's Press, 1999.

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Frank, Smith. Acts of vengeance. New York: St. Martin's Minotaur, 2003.

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Antić, Čedomir, und Чедомир Антић. Ralph Paget: A diplomat in Serbia. Beograd: Balkanološki institut SANU, 2006.

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Frank, Smith. Thread of evidence. New York: St. Martin's Minotaur, 2001.

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Frank, Smith. Thread of evidence. New York: St. Martin's Minotaur, 2001.

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Frank, Smith. In the shadow of evil: A DCI Neil Paget mystery. London: Severn House Large Print, 2014.

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Buchteile zum Thema "Paget":

1

Pietschmann, Diethard, und Vera Pietschmann. „Paget-Karzinom“. In Lexikon der Mammadiagnostik, 104–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72101-4_38.

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2

Bork, Konrad. „Morbus Paget“. In Dermatologische Onkologie, 499–504. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60622-9_55.

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Heenan, Peter J., David E. Elder und L. H. Sobin. „Paget Disease“. In Histological Typing of Skin Tumours, 68. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80126-6_6.

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Niedhart, Christopher. „Morbus Paget“. In Fortbildung Osteologie, 34–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-05385-6_9.

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Scharla, Stephan. „Morbus Paget“. In DGIM Innere Medizin, 1–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-642-54676-1_416-1.

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Trambaiolo Antonelli, Chiara, und Francesca Portelli. „Extramammary Paget Disease“. In Encyclopedia of Pathology, 1–4. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-28845-1_4868-1.

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7

Kanitakis, Jean. „Maladie de Paget“. In Manifestations dermatologiques des maladies du système hématopoïétique et oncologie dermatologique, 151–59. Paris: Springer Paris, 2009. http://dx.doi.org/10.1007/978-2-287-72092-5_13.

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Merritt, Bradley G., und David G. Brodland. „Extramammary Paget Disease“. In Mohs Micrographic Surgery, 263–78. London: Springer London, 2011. http://dx.doi.org/10.1007/978-1-4471-2152-7_22.

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Vesel, Živa, Leonardo Gariboldi, Steven L. Renshaw, Saori Ihara, İhsan Fazlıoğlu, Voula Saridakis, Michael Fosmire et al. „Thomson, George Paget“. In The Biographical Encyclopedia of Astronomers, 1139–40. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-30400-7_1380.

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Kant, Horst. „Thomson, George Paget“. In Biographical Encyclopedia of Astronomers, 2156–57. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4419-9917-7_1380.

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Konferenzberichte zum Thema "Paget":

1

Alzahr, A., M. Mansour und B. Knof. „Paget Krankheit im Felsenbein“. In Abstract- und Posterband – 89. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Forschung heute – Zukunft morgen. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1640233.

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van der Linden, M., K. Meeuwis, C. van Hees, E. van Dorst, J. Bulten, T. Bosse, J. IntHout et al. „P191 Paget trial: topical 5% imiquimod for vulvar paget disease, first results of clinical efficacy“. In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.248.

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Dornhöfer, N., R. Handzel und B. Aktas. „Konservatives Management eines vulvären M. Paget“. In Kongressabstracts zur 13. Jahrestagung der Mitteldeutschen Gesellschaft für Frauenheilkunde und Geburtshilfe e.V. (MGFG). Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1692080.

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Neubert, M., A. Petzold und P. Wimberger. „Der isolierte Morbus Paget der Mamille“. In 12. Jahrestagung der Mitteldeutschen Gesellschaft für Frauenheilkunde und Geburtshilfe e.V. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1645910.

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Neubert, M., A. Petzold und P. Wimberger. „Der isolierte Morbus Paget der Mamille“. In 38. Jahrestagung der Deutschen Gesellschaft für Senologie. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1651770.

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Belluco, Rosana Zabulon Feijó, Flávio Lúcio Vasconcelos, Paulo Eduardo Silva Belluco, Júllia Eduarda Feijó Belluco und Carmelia Matos Santiago Reis. „NIPPLE MINIMUM PAGET DISEASE: A CASE REPORT“. In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1059.

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Annotation:
Paget’s disease (PD) of the nipple is a rare cancer that affects the nipple and areola and accounts for between 0.4% and 5% of breast cancers. It was first described in 1877 by the English physician Sir James Paget. It affects women between 60 and 70 years of age and very rarely affects men. In PD, the skin on the nipple and areola becomes thicker. Clinical presentations are usually erythema, desquamation, or eczematous changes in the nipple, features that can progressively progress to erosion, overt destruction, and ulceration of the papilla. Bloody papillary discharge, itching, nipple retraction, and/or a palpable mass may be associated. Cancer cells, called Paget cells, are malignant, large, with clear, abundant cytoplasm and nuclei with prominent nucleoli. Like glandular cells, they appear either as isolated cell in the epidermal tissue or as groups of cells. Most women diagnosed with PD also have ductal adenocarcinoma, either in situ or invasive. The prevalence is 67–100% of cases, which gives a worse prognosis to the patient. Patients with Paget-associated invasive breast disease have lower hormone receptor expression, greater lymph node involvement, and higher human epidermal growth factor receptor type 2 (HER2) expression. An 82-year-old woman sought the mastology outpatient clinic for a follow-up of carcinoma in situ in the right breast 2 years ago, having been submitted to quadrantectomy and hormone therapy with tamoxifen, with no signs of recurrence. She complained of an exudative pruritic lesion on the left nipple that had started 6 months ago. She reported that the lesion started with itching and burning, associated with a spontaneous discharge of serous secretion from the itchy surface of the breast, which improved with the use of “talcum powder.” On physical examination, the presence of a discrete reddened area with a diameter of 3 mm, eczematous, with bloody areas interspersed with serous secretion was observed on the left nipple. Areola lesions and palpable nodules in the left breast were absent. She underwent mammography, which showed symmetrical breasts with fat-replaced parenchyma, absence of nodules, presence of isolated calcifications, and grouping in the superior lateral region of the left breast, categorized as BIRADS II. On ultrasound, a nodule with angled edges, measuring 5×4 mm in the superomedial quadrant of the left breast, which showed nodular enhancement and persistent kinetic curve on magnetic resonance imaging of the breasts. The histopathological study diagnosed moderately differentiated left breast ductal carcinoma, associated with a high-grade solid intraductal carcinoma and PD of the nipple, without the involvement of the areola. Immunohistochemistry revealed the absence of estrogen and progesterone hormone receptors and HER-2 overexpression in both histological types. She underwent mastectomy with sentinel lymph node biopsy that was free of neoplasia. Oncological follow-up with no signs of recurrence. PD, if left untreated, extends to the areola and other regions of the breast. Therefore, clinical suspicion from the first physical examination allows an early diagnosis of extreme importance, which improves the prognosis and allows less aggressive treatments.
7

Martin, A. A., Moreno Marcelo, R. Bitar, H, Martinho, E. A. P. Santos und E. A. L. Arisawa. „Can Raman spectroscopy identify the origin of Paget disease?“ In Biomedical Optics (BiOS) 2008, herausgegeben von Anita Mahadevan-Jansen, Wolfgang Petrich, Robert R. Alfano und Alvin Katz. SPIE, 2008. http://dx.doi.org/10.1117/12.760097.

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Batra, S., und K. Maken. „Bilateral Chylothorax in a Patient with Paget-Schroetter Syndrome“. In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2243.

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Mea, Vivian Pena Della, Tatiana Casaburi Smiderle, Luiz José Moura Alimena, Caroline Maria de Castilhos Vieira, Vinicius Visioli de Vargas und Carla Cristani. „OSTEOSSARCOMA SECUNDÁRIO À DOENÇA DE PAGET: RELATO DE CASO“. In II Congresso Online Brasileiro de Medicina. Congresse.me, 2022. http://dx.doi.org/10.54265/pjvf1049.

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„TERN/AusCover - Remote sensing data management for terrestrial ecosystem research“. In 19th International Congress on Modelling and Simulation. Modelling and Simulation Society of Australia and New Zealand (MSSANZ), Inc., 2011. http://dx.doi.org/10.36334/modsim.2011.h4.paget.

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Berichte der Organisationen zum Thema "Paget":

1

Tobin, J. OBES "One Pager". Office of Scientific and Technical Information (OSTI), November 2008. http://dx.doi.org/10.2172/945649.

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Postel, J., und C. Anderson. White Pages Meeting Report. RFC Editor, Februar 1994. http://dx.doi.org/10.17487/rfc1588.

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3

Osborn, S., und C. Ponce. MT-CFAFI 2-Pager. Office of Scientific and Technical Information (OSTI), Oktober 2021. http://dx.doi.org/10.2172/1830944.

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Johnson, Randall P., und Juan C. Fernandez. Trident Web page. Office of Scientific and Technical Information (OSTI), Juni 2012. http://dx.doi.org/10.2172/1044848.

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Merritt, Elizabeth. NIF 3-pager FY24: Mshock. Office of Scientific and Technical Information (OSTI), Februar 2023. http://dx.doi.org/10.2172/1924406.

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Woodruff, W. L., und R. S. Smith. A users guide for the ANL version of the PARET code, PARET/ANL (2001 Rev.). Office of Scientific and Technical Information (OSTI), Dezember 2001. http://dx.doi.org/10.2172/789681.

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Olson, A. P., B. Dionne, A. Marin-Lafleche und M. Kalimullah. A User Guide to PARET/ANL. Office of Scientific and Technical Information (OSTI), Januar 2015. http://dx.doi.org/10.2172/1184194.

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Olson, A. P., und M. Kalimullah. A User Guide to PARET/ANL. Office of Scientific and Technical Information (OSTI), April 2018. http://dx.doi.org/10.2172/1463237.

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Olson, A. P., und M. Kalimullah. A User Guide to PARET/ANL. Office of Scientific and Technical Information (OSTI), März 2019. http://dx.doi.org/10.2172/1501911.

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Resnik, P. Evaluating Multilingual Gisting of Web Pages. Fort Belvoir, VA: Defense Technical Information Center, März 1997. http://dx.doi.org/10.21236/ada458592.

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