Auswahl der wissenschaftlichen Literatur zum Thema „Paraffinolja“

Abstract We report the case of an 84-year-old man with multiple squamous cell carcinomas located on his bald scalp, arising in association with underlying paraffinoma. Histologically, poorly differentiated, acantholytic squamous cell carcinomas were located above characteristic pseudocystic spaces. Carcinomas have been reported in association with penile and breast paraffinomas, but we are unaware of any reports of squamous cell carcinoma arising over a scalp paraffinoma.

Penile paraffinoma is an uncommon entity produced by penile paraffin injections for the purpose of penile enlargement by a nonmedical person. Although it is not a current method of penile enlargement procedures, in our opinion dermatologists and urology specialist should be have knowledge of this entity about diagnosis and management. It will be an aim to share our experiences and views in this paper.

AbstractParaffin impregnated tulle is frequently used as a post-operative dressing after surgical repair of wounds, on skin-donor sites and in packing of tissue cavities. Historically, paraffin has been injected into various sites of the body and paraffinoma is a well-described complication. Despite this, nasal packing with paraffin gauze is still common after rhinoplasty. We report a case of paraffinoma occurring after rhinoplasty and discuss the avoidance of this rare but serious complication and suggest silicon mesh as an alternative dressing.

Fuktbevarare är de produkter som oftast skrivs och rekommenderas av dermatologer, och den vanligaste typen av fuktgivare är lotioner och krämer. Dessa produkter är emulsioner, vilka ofta innehåller medicinsk vit olja (MWO) på grund av deras skyddande egenskaper samt enastående hudkompabilitet. Traditionellt så har de MWO som används varit parafinska. Då naftenoljor ofta har visat sig ha bättre emulsions stabilitet, har detta examensarbete ämnat attjämföra emulsions stabiliteten för Nynas ABs nya MWO, N-MWO, med en parafinsk motsvarighet, P-MWO. Jämförelsen av de två oljorna genomfördes genom att variera följande faktorer: olje- och emulgator typ, koncentration av emulgator samt både med och utan parfym. De två emulgator system som användes bestod av Promulgen D (en kommersiell produkt från Lubrizol) samt kombinationen av Tween 80 och Span 20. Bättre emulsionsstabilitet och mindre droppstorlek och fördelning utficks då högre koncentration Promulgen D användes. En högre koncentration av Tween 80 och Span 20 gav dock inte samma gynnsamma effekt. Resultaten från samtliga tester påvisade att emulsions stabiliteten inte påverkades utav parfym. Det som istället gav störst påverkan var typ av emulgator. De prover som innehöll P-MWO samt Tween 80 och Span 20 fasseparerade. Detta berodde dock troligen mer på att P-MWO inte var kompatibel med dessa emulgatorer eftersom oljetypen inte påverkade emulsionsstabiliteten när Promulgen D användes som emulgator.
Moisturizers are the most prescribed products in dermatology, and the most common type of moisturizer delivery systems are lotions and creams. These are emulsions and often contain medical white oil (MWO) due to their protective properties and excellent skin compatibility. The MWO used in cosmetics have traditionally been paraffinic. However, as naphthenic oils often have been proven to create better emulsion stability, this thesis aimed to compare Nynas AB's new MWO, N-MWO, with a paraffinic oil, P-MWO, with similar properties regarding their emulsion stability. The two oils were compared by analyzing their emulsion stability using a rheometer and a Mastersizer 3000 while varying the following factors: type of oil, type of emulsifier, emulsifier concentration, and with and without perfume. The two emulsifying systems used were the commercial product Promulgen D from Lubrizol and the combination of Tween 80 and Span 20. Better emulsion stability and smaller droplet size distribution were obtained when a higher content of Promulgen D was added. However, a higher concentration of Tween 80 and Span 20 did not have the same favorable effect. The results showed that the addition of perfume had no effect, while the type of emulsifier influenced the emulsion stability the most. The samples made from Supela 240 and Tween 80 and Span 20 phase separated. This was more likely due to P-MWOs incompatibility with these emulsifiers as oil type did not influence the emulsion stability when Promulgen D was used as an emulsifier.

Lipoid pneumonia is an unusual form of lung disease resulting from the accumulation of lipids in the alveoli, where they provoke a foreign body reaction with associated inflammation and sometimes local fibrosis. The lipids may be endogenous or exogenous in origin, and the clinical mechanisms and circumstances differ accordingly. Exogenous lipoid pneumonia occurs when animal, vegetable, or mineral oils are aspirated or inhaled into the lungs, provoking a foreign body reaction with chronic inflammation. Typical symptoms are cough and breathlessness. The chest radiograph and CT may show interstitial thickening, with areas of consolidation that may coalesce into a mass (paraffinoma) which simulates carcinoma. Bronchoalveolar lavage and biopsy show lipid-laden macrophages. In endogenous lipoid pneumonia the lipids are derived from surfactant and cholesterol released from decaying cells distal to bronchial obstruction.