Thematische Bibliographien / Photoactivatable systems

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Auswahl der wissenschaftlichen Literatur zum Thema „Photoactivatable systems“

Autor: Grafiati

Veröffentlicht am 11. Januar 2025

Zuletzt aktualisiert am 31. Juli 2025

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Zeitschriftenartikel zum Thema "Photoactivatable systems"

Raymo, Françisco M. "Photoactivatable Fluorophores." ISRN Physical Chemistry 2012 (September 17, 2012): 1–15. http://dx.doi.org/10.5402/2012/619251.

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Photoactivatable fluorophores switch from a nonemissive to an emissive state upon illumination at an activating wavelength and then emit after irradiation at an exciting wavelength. The interplay of such activation and excitation events can be exploited to switch fluorescence on in a defined region of space at a given interval of time. In turn, the spatiotemporal control of fluorescence translates into the opportunity to implement imaging and spectroscopic schemes that are not possible with conventional fluorophores. Specifically, photoactivatable fluorophores permit the monitoring of dynamic

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Nihongaki, Yuta, Yuichi Furuhata, Takahiro Otabe, Saki Hasegawa, Keitaro Yoshimoto, and Moritoshi Sato. "CRISPR–Cas9-based photoactivatable transcription systems to induce neuronal differentiation." Nature Methods 14, no. 10 (2017): 963–66. http://dx.doi.org/10.1038/nmeth.4430.

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Gil, Melina D., Silvestre Bongiovanni Abel, César A. Barbero, Natalia S. Paulucci, and Edith I. Yslas. "Low-Power NIR-Triggered Photothermal Inactivation of Pseudomonas aeruginosa with Polypyrrole Nanoparticles." Polymers 17, no. 11 (2025): 1442. https://doi.org/10.3390/polym17111442.

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Conducting polymer (CP) nanoparticles have emerged as innovative materials for biomedical applications, particularly due to their safe interaction with biological systems. This study focuses on the synthesis, morphological, and spectroscopic characterization of polypyrrole nanoparticles (PPy-NPs) as photoactivatable agents under near-infrared (NIR) radiation for the inactivation of pathogenic bacteria. We successfully synthesized uniform nanoparticles (~180 nm) with strong absorption in the NIR region. A comprehensive characterization was performed using electron microscopy, dynamic light scat

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Smith, Nichola A., and Peter J. Sadler. "Photoactivatable metal complexes: from theory to applications in biotechnology and medicine." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 371, no. 1995 (2013): 20120519. http://dx.doi.org/10.1098/rsta.2012.0519.

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This short review highlights some of the exciting new experimental and theoretical developments in the field of photoactivatable metal complexes and their applications in biotechnology and medicine. The examples chosen are based on some of the presentations at the Royal Society Discussion Meeting in June 2012, many of which are featured in more detail in other articles in this issue. This is a young field. Even the photochemistry of well-known systems such as metal–carbonyl complexes is still being elucidated. Striking are the recent developments in theory and computation (e.g. time-dependent

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Snapp, E. L., and P. Lajoie. "Activating Photoactivatable Proteins with Laser Light to Visualize Membrane Systems and Membrane Traffic in Living Cells." Cold Spring Harbor Protocols 2011, no. 11 (2011): pdb.prot066571. http://dx.doi.org/10.1101/pdb.prot066571.

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Ivanskaya, E. V., M. I. Meschaninova, M. A. Vorobyeva, D. O. Zharkov, and D. S. Novopashina. "The approach to the preparation of cyclic photocleavable RNA for photoactivatable CRISPR/Cas9 System." Биоорганическая химия 50, no. 5 (2024): 622–35. https://doi.org/10.31857/s0132342324050051.

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The development of controllable gene editing systems on the base of CRISPR/Cas is an actually problem of modern molecular biology and genetic enginery. Interesting variant of solution of this problem is modification of guide RNA by introduction of photocleavable linkers. We developed the approach to the synthesis of cyclic photocleavable guide crRNA for the CRISPR/Cas9 system with photolinker on the base of 1-(2-nitrophenyl)-1,2-ethanediol (PL). Upon irradiation by UV-light these guide RNA are linearized and CRISPR/Cas9 system is activated. Two chemical methods to the cyclization of RNA were t

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Li, Huiying, Qiansen Zhang, Yiran Gu, et al. "Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse." Proceedings of the National Academy of Sciences 117, no. 52 (2020): 33426–35. http://dx.doi.org/10.1073/pnas.2003991117.

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Precise genetic engineering in specific cell types within an intact organism is intriguing yet challenging, especially in a spatiotemporal manner without the interference caused by chemical inducers. Here we engineered a photoactivatable Dre recombinase based on the identification of an optimal split site and demonstrated that it efficiently regulated transgene expression in mouse tissues spatiotemporally upon blue light illumination. Moreover, through a double-floxed inverted open reading frame strategy, we developed a Cre-activated light-inducible Dre (CALID) system. Taking advantage of well

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Valueva, Anastasia A., Ivan D. Shumov, Anna L. Kaysheva, et al. "Covalent Protein Immobilization onto Muscovite Mica Surface with a Photocrosslinker." Minerals 10, no. 5 (2020): 464. http://dx.doi.org/10.3390/min10050464.

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Muscovite mica with an amino silane-modified surface is commonly used as a substrate in atomic force microscopy (AFM) studies of biological macromolecules. Herein, the efficiency of two different protein immobilization strategies employing either (N-hydroxysuccinimide ester)-based crosslinker (DSP) or benzophenone-based photoactivatable crosslinker (SuccBB) has been compared using AFM and mass spectrometry analysis. Two proteins with different physicochemical properties—human serum albumin (HSA) and horseradish peroxidase enzyme protein (HRP)—have been used as model objects in the study. In th

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Maronde, Erik. "Cyclic Nucleotide (cNMP) Analogues: Past, Present and Future." International Journal of Molecular Sciences 22, no. 23 (2021): 12879. http://dx.doi.org/10.3390/ijms222312879.

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Cyclic nucleotides are important second messengers involved in cellular events, and analogues of this type of molecules are promising drug candidates. Some cyclic nucleotide analogues have become standard tools for the investigation of biochemical and physiological signal transduction pathways, such as the Rp-diastereomers of adenosine and guanosine 3′,5′-cyclic monophosphorothioate, which are competitive inhibitors of cAMP- and cGMP-dependent protein kinases. Next generation analogues exhibit a higher membrane permeability, increased resistance against degradation, and improved target specifi

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Ferenz, Nick P., and Patricia Wadsworth. "Prophase Microtubule Arrays Undergo Flux-like Behavior in Mammalian Cells." Molecular Biology of the Cell 18, no. 10 (2007): 3993–4002. http://dx.doi.org/10.1091/mbc.e07-05-0420.

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In higher eukaryotic cells, microtubules within metaphase and anaphase spindles undergo poleward flux, the slow, poleward movement of tubulin subunits through the spindle microtubule lattice. Although a number of studies have documented this phenomenon across a wide range of model systems, the possibility of poleward flux before nuclear envelope breakdown (NEB) has not been examined. Using a mammalian cell line expressing photoactivatable green fluorescent protein (GFP)-tubulin, we observe microtubule motion, both toward and away from centrosomes, at a wide range of rates (0.5–4.5 μm/min) in p

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Dissertationen zum Thema "Photoactivatable systems"

Xu, Jianan. "Nanoparticules de silice et leur fonctionnalisation avec des systèmes photoactivables." Electronic Thesis or Diss., Lyon, École normale supérieure, 2024. http://www.theses.fr/2024ENSL0063.

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La silice mésoporeuse est un support polyvalent largement utilisé dans le domaine biomédical et de la catalyse en raison de ses propriétés intéressantes. Dans ce travail, la silice mésoporeuse a d'abord été utilisée comme support pour des applications de thérapie photodynamique (PDT). La PDT est réalisée par l'excitation d'un photosensibilisateur (PS) avec de la lumière visible à certaines longueurs d'onde, puis le PS excité peut soit conduire des réactions de transfert d'électrons vers/depuis des molécules biologiques (mécanisme de type I) ou, alternativement, transférer son énergie à l'oxygè

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Huang, Cheng-Wen, and 黃政文. "Tracing Neuronal Projections with Photoactivatable GFP in the Olfactory System of Drosophila." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/99677373261377953106.

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碩士<br>國立清華大學<br>生物科技研究所<br>95<br>Recent advances in sensory neuroscience using Drosophila olfaction as a model system have revealed partial map for the representation of the external world within its brain. Currently, three levels of wiring in antenna lobe (AL) are known. Odorants are detected by the olfactory sensory neurons (OSNs), located on the antenna (Ant) and maxillary palp (MP), sending axons via the antennal nerve (AN) and the labial nerve (LN), respectively, to AL (Level 1); where the projection neurons (PNs) receive and calculate the information (Level 2) and then relay to the mushr

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Buchteile zum Thema "Photoactivatable systems"

Sun, Jiangman, Hui Li, Xinggui Gu, and Ben Zhong Tang. "Chapter 11 AIE-based systems for photoactivatable imaging, delivery, and therapy." In Aggregation-Induced Emission. De Gruyter, 2022. http://dx.doi.org/10.1515/9783110672220-011.

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