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1

HAMAGUCHI, Hiroo. "Physicochemical Approach to Life." TRENDS IN THE SCIENCES 14, no. 3 (2009): 22–24. http://dx.doi.org/10.5363/tits.14.3_22.

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2

Defoort, Françoise, Matthieu Campargue, Gilles Ratel, Hélène Miller, and Capucine Dupont. "Physicochemical Approach To Blend Biomass." Energy & Fuels 33, no. 7 (2019): 5820–28. http://dx.doi.org/10.1021/acs.energyfuels.8b04169.

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3

van Loosdrecht, Mark C. M., Johannes Lyklema, Willem Norde, and Alexander J. B. Zehnder. "Bacterial adhesion: A physicochemical approach." Microbial Ecology 17, no. 1 (1989): 1–15. http://dx.doi.org/10.1007/bf02025589.

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4

Ohgaki, Kazunari, Nguyen Quoc Khanh, Yasuhiro Joden, Atsushi Tsuji, and Takaharu Nakagawa. "Physicochemical approach to nanobubble solutions." Chemical Engineering Science 65, no. 3 (2010): 1296–300. http://dx.doi.org/10.1016/j.ces.2009.10.003.

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5

Greenbaum, Jonathan, and Mahesh Nirmalan. "Acid–base balance: Stewart's physicochemical approach." Current Anaesthesia & Critical Care 16, no. 3 (2005): 133–35. http://dx.doi.org/10.1016/j.cacc.2005.03.010.

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6

Lutfiyah, Dhea Sultana, Lili Fitriani, Muhammad Taher, and Erizal Zaini. "Crystal Engineering Approach in Physicochemical Properties Modifications of Phytochemical." Science and Technology Indonesia 7, no. 3 (2022): 353–71. http://dx.doi.org/10.26554/sti.2022.7.3.353-371.

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Phytochemicals have been used to reduce the risk of diseases and maintain good health and well-being. However, most phytochemicals have a limitation in their physicochemical properties, which can be modified by reforming the shape of the crystals. Therefore, crystal engineering is a promising approach to optimize physicochemical characteristics of the active pharmaceutical ingredients (APIs) in a phytochemical without altering its pharmacological efficacy. Hence, this paper reviews current strategies for the use of crystal engineering to optimize physicochemical properties of phytochemicals, w
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Iritani, Eiji, and Yasuhito Mukai. "Approach from physicochemical aspects in membrane filtration." Korean Journal of Chemical Engineering 14, no. 5 (1997): 347–53. http://dx.doi.org/10.1007/bf02707050.

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8

Kocherginsky, Nikolai, and Martin Gruebele. "Mechanical approach to chemical transport." Proceedings of the National Academy of Sciences 113, no. 40 (2016): 11116–21. http://dx.doi.org/10.1073/pnas.1600866113.

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Nonequilibrium thermodynamics describes the rates of transport phenomena with the aid of various thermodynamic forces, but often the phenomenological transport coefficients are not known, and the description is not easily connected with equilibrium relations. We present a simple and intuitive model to address these issues. Our model is based on Lagrangian dynamics for chemical systems with dissipation, so one may think of the model as physicochemical mechanics. Using one main equation, the model allows a systematic derivation of all transport and equilibrium equations, subject to the limitatio
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Diaztagle-Fernández, José Diaztagle, Ingrid Juliana Moreno-Ladino, Jorge Alfredo Morcillo-Muñoz, Andrés Felipe Morcillo-Muñoz, Luis Alejandro Marcelo-Pinilla, and Luis Eduardo Cruz-Martínez. "Comparative analysis of acid-base balance in patients with severe sepsis and septic shock: traditional approach vs. physicochemical approach." Revista de la Facultad de Medicina 67, no. 4 (2019): 441–46. http://dx.doi.org/10.15446/revfacmed.v67n4.65448.

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Introduction: The evaluation of metabolism and the diagnostic classification of acid-base disorders has generated great controversy. Acid-base balance (ABB) is approached by means of the physicochemical and Henderson’s models.Objective: To compare two diagnostic approaches to ABB in patients with severe sepsis.Materials and methods: Prospective, descriptive study conducted in patients with severe sepsis. ABB was analyzed within the first 24 hours. The diagnosis was compared according to each model and the causes of the disorders were compared according to the physicochemical model.Results: 38
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Rodríguez-García, J., A. Puig, A. Salvador, and I. Hernando. "Funcionality of several cake ingredients: A comprehensive approach." Czech Journal of Food Sciences 31, No. 4 (2013): 355–60. http://dx.doi.org/10.17221/412/2012-cjfs.

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The roles of some cake ingredients – oil, a leavening agent, and inulin – in the structure and physicochemical properties of batter and cakes were studied in four different formulations. Oil played an important role in the batter stability, due to its contribution to increasing batter viscosity and occluding air during mixing. The addition of the leavening agent was crucial to the final height and sponginess of the cakes. When inulin was used as a fat replacer, the absence of oil caused a decrease in the stability of the batter, where larger air bubbles were occluded. Inuli
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Adrogué, Horacio J., and Nicolaos E. Madias. "Assessing Acid-Base Status: Physiologic Versus Physicochemical Approach." American Journal of Kidney Diseases 68, no. 5 (2016): 793–802. http://dx.doi.org/10.1053/j.ajkd.2016.04.023.

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12

Durand, M., and D. Langevin. "Physicochemical approach to the theory of foam drainage." European Physical Journal E 7, no. 1 (2002): 35–44. http://dx.doi.org/10.1140/epje/i200101092.

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13

Turova, N. Ya, E. P. Turevskaya, M. I. Yanovskaya, A. I. Yanovsky, V. G. Kessler, and D. E. Tcheboukov. "Physicochemical approach to the studies of metal alkoxides." Polyhedron 17, no. 5-6 (1998): 899–915. http://dx.doi.org/10.1016/s0277-5387(97)00256-8.

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14

Jones, Norman L. "A quantitative physicochemical approach to acid-base physiology." Clinical Biochemistry 23, no. 3 (1990): 189–95. http://dx.doi.org/10.1016/0009-9120(90)90588-l.

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15

Savjani, Jignasa Ketan, and Chirag Pathak. "Improvement of physicochemical parameters of acyclovir using cocrystallization approach." Brazilian Journal of Pharmaceutical Sciences 52, no. 4 (2016): 727–34. http://dx.doi.org/10.1590/s1984-82502016000400017.

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16

Simonen, Markus, Timo Blomberg, Terhi Pellinen, Michalina Makowska, and Jarkko Valtonen. "Curing and ageing of biofluxed bitumen: a physicochemical approach." Road Materials and Pavement Design 14, no. 1 (2013): 159–77. http://dx.doi.org/10.1080/14680629.2012.755933.

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17

Maciel, Alexandre Toledo, and Marcelo Park. "A physicochemical acid-base approach for managing diabetic ketoacidosis." Clinics 64, no. 7 (2009): 714–18. http://dx.doi.org/10.1590/s1807-59322009000700018.

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18

Prochazkova, Gita, Nikola Podolova, Ivo Safarik, Vilem Zachleder, and Tomas Branyik. "Physicochemical approach to freshwater microalgae harvesting with magnetic particles." Colloids and Surfaces B: Biointerfaces 112 (December 2013): 213–18. http://dx.doi.org/10.1016/j.colsurfb.2013.07.053.

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19

Hua, Jingfeng, Mimi Ji, Ping Jiao, et al. "Heterogeneous Acid Catalysts for Biodiesel Production: Effect of Physicochemical Properties on Their Activity and Reusability." Catalysts 15, no. 4 (2025): 396. https://doi.org/10.3390/catal15040396.

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Replacing homogeneous acids with heterogeneous acids provides an appealing approach for biodiesel production due to their reusability and easy recycling. The physicochemical properties of heterogeneous acids have a significant influence on catalytic activity and reusability. Herein, the influence of physicochemical properties (i.e., acid density, acid strength, acid type, wettability, thermal sensitivity, and magnetism) on catalytic activity and recyclability is elaborately discussed. Characterization techniques for identifying physicochemical properties are elaborated. Methods for regulating
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Mayur, Dukare* Rafey Shaikh Rutuja Hirde Gaurav Sonune Surbhi Rawka Dr. Rao Javvaji. "Formulation and Evaluation of Herbal Shampoo." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 137–43. https://doi.org/10.5281/zenodo.15572106.

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The increasing demand for natural and eco-friendly cosmetic products has led to the development of herbal shampoos as alternatives to synthetic formulations. This study focuses on the formulation and evaluation of a herbal shampoo using various plant-based ingredients known for their cleansing, conditioning, and antimicrobial properties. Selected herbs such as Neem, Acacia concinna (Shikakai), Hibiscus rosa-sinensis, Aloe vera, and Phyllanthus emblica (Amla) were used in the formulation. The prepared shampoo was evaluated for physicochemical parameters including pH, viscosity, foam stability,
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21

Watanabe, Naoki, and Masashi Tsuge. "Experimental Approach to Physicochemical Hydrogen Processes on Cosmic Ice Dust." Journal of the Physical Society of Japan 89, no. 5 (2020): 051015. http://dx.doi.org/10.7566/jpsj.89.051015.

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22

Nakashima, Shoko, Katsuhiko Yamamoto, Yuta Arai, and Yukihiro Ikeda. "Impact of Physicochemical Profiling for Rational Approach on Drug Discovery." Chemical and Pharmaceutical Bulletin 61, no. 12 (2013): 1228–38. http://dx.doi.org/10.1248/cpb.c13-00436.

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23

Nijhawan, Monika, Rajeswari Aleti, Sailaja Gunnam, and Sneha Nawale. "SPHERICAL AGGLOMERATION OF TELMISARTAN - AN APPROACH TO IMPROVE PHYSICOCHEMICAL PROPERTIES." INDIAN DRUGS 61, no. 08 (2024): 38–43. http://dx.doi.org/10.53879/id.61.08.14698.

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The study explains the preparation of spherical agglomerates (SA) of telmisartan (TLS), a BCS class II drug used to improve it’s physicochemical and bulk properties. Drugs of this class could potentially exhibit dissolution rate limited absorption. TLS spherical agglomerates were designed using hydrophilic polymer (PVP K-30), dimethyl formamide (DMF), water and ethyl acetate (bridging liquid) by solvent change method and evaluated for micromeritic properties. The SA were characterized by particle size determination, FTIR, PXRD and SEM. The results of micromeritic studies indicated that SA show
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24

Riabtseva, Anna, Leonid I. Kaberov, Jan Kučka, et al. "Polyelectrolyte pH-Responsive Protein-Containing Nanoparticles: The Physicochemical Supramolecular Approach." Langmuir 33, no. 3 (2017): 764–72. http://dx.doi.org/10.1021/acs.langmuir.6b03778.

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25

Usherov-Marshak, A. V. "Phenomenological approach to building materials development based on physicochemical analysis." Inorganic Materials 47, no. 8 (2011): 926–29. http://dx.doi.org/10.1134/s0020168511080218.

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26

Özdemir, Zeliha, Birgin Törer, Deniz Hanta, Bilin Cetinkaya, Hande Gulcan, and Aylin Tarcan. "Determination of tissue hypoxia by physicochemical approach in premature anemia." Pediatrics & Neonatology 58, no. 5 (2017): 425–29. http://dx.doi.org/10.1016/j.pedneo.2016.09.003.

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27

Ma, Tiantian, Chuanqin Yao, Yi Dong, Panpan Yi, and Changfu Wei. "Physicochemical approach to evaluating the swelling pressure of expansive soils." Applied Clay Science 172 (May 2019): 85–95. http://dx.doi.org/10.1016/j.clay.2019.02.011.

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28

Libório, Alexandre Braga, Elizabeth F. Daher, and Manuel Carlos Martins de Castro. "Characterization of acid-base status in maintenance hemodialysis: physicochemical approach." Journal of Artificial Organs 11, no. 3 (2008): 156–59. http://dx.doi.org/10.1007/s10047-008-0419-2.

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29

Cox, Philip B., Robert J. Gregg, and Anil Vasudevan. "Abbott Physicochemical Tiering (APT)—A unified approach to HTS triage." Bioorganic & Medicinal Chemistry 20, no. 14 (2012): 4564–73. http://dx.doi.org/10.1016/j.bmc.2012.05.047.

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30

TUROVA, N. Y., E. P. TUREVSKAYA, M. I. YANOVSKAYA, A. I. YANOVSKY, V. G. KESSLER, and D. E. TCHEBOUKOV. "ChemInform Abstract: Physicochemical Approach to the Studies of Metal Alkoxides." ChemInform 29, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.199834306.

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31

Lynn, David G., та Stephen C. Meredith. "Review: Model Peptides and the Physicochemical Approach to β-Amyloids". Journal of Structural Biology 130, № 2-3 (2000): 153–73. http://dx.doi.org/10.1006/jsbi.2000.4287.

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32

Stoppe, Nina, and Rainer Horn. "Microstructural strength of tidal soils – a rheometric approach to develop pedotransfer functions." Journal of Hydrology and Hydromechanics 66, no. 1 (2018): 87–96. http://dx.doi.org/10.1515/johh-2017-0031.

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Abstract Differences in soil stability, especially in visually comparable soils can occur due to microstructural processes and interactions. By investigating these microstructural processes with rheological investigations, it is possible to achieve a better understanding of soil behaviour from the mesoscale (soil aggregates) to macroscale (bulk soil). In this paper, a rheological investigation of the factors influencing microstructural stability of riparian soils was conducted. Homogenized samples of Marshland soils from the riparian zone of the Elbe River (North Germany) were analyzed with am
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Joshi, Sravani, and Ruby Srivastava. "Effect of “magic chlorine” in drug discovery: an in silico approach." RSC Advances 13, no. 49 (2023): 34922–34. http://dx.doi.org/10.1039/d3ra06638j.

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34

Yuan, Jiuchuang, Xuetao Liu, Simin Wang, et al. "Virtual coformer screening by a combined machine learning and physics-based approach." CrystEngComm 23, no. 35 (2021): 6039–44. http://dx.doi.org/10.1039/d1ce00587a.

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35

Singh, Maan, Harsh Barua, Vaskuri G. S. Sainaga Jyothi, et al. "Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems." Pharmaceutics 15, no. 4 (2023): 1161. http://dx.doi.org/10.3390/pharmaceutics15041161.

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Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and stability present a significant challenge during their processing into final dosage forms. Cocrystallization of such APIs with suitable coformers is an efficient approach to mitigate the solubility and stability concerns. A considerable number of cocrystal-based products are currently being marketed and show an upward trend. However, to improve the API properties by cocrystallization, coformer selection plays a paramount role. Selection of suitable coformers not only improves the drug’s physicochemical prop
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36

Kocherginsky, Nikolai Meerovich. "Physicochemical Mechanics and Nonequilibrium Chemical Thermodynamics." Entropy 25, no. 9 (2023): 1332. http://dx.doi.org/10.3390/e25091332.

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Equilibrium thermodynamics answers the question, “by how much?” Nonequilibrium thermodynamics answers the question “how fast?” The physicochemical mechanics approach presented in this article answers both of these questions. It also gives equilibrium laws and expressions for all major transport coefficients and their relations, which was previously impossible. For example, Onsager’s reciprocal relations only tell us that symmetric transport coefficients are equal, and even for these, the value is often not known. Our new approach, applicable to non-isolated systems, leads to a new formulation
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37

Meesters, J. A. J., J. T. K. Quik, A. A. Koelmans, A. J. Hendriks, and D. van de Meent. "Multimedia environmental fate and speciation of engineered nanoparticles: a probabilistic modeling approach." Environmental Science: Nano 3, no. 4 (2016): 715–27. http://dx.doi.org/10.1039/c6en00081a.

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The robustness of novel multimedia fate models in environmental exposure estimation of engineered nanoparticles (ENPs) is clarified by evaluating uncertainties in the emission, physicochemical properties and natural variability in environmental systems.
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38

Gontar, V. "Theoretical foundation for the discrete dynamics of physicochemical systems: Chaos, self-organization, time and space in complex systems." Discrete Dynamics in Nature and Society 1, no. 1 (1997): 31–43. http://dx.doi.org/10.1155/s1026022697000058.

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A new theoretical foundation for the discrete dynamics of physicochemical systems is presented. Based on the analogy between theπ-theorem of the theory of dimensionality, the second law of thermodynamics and the stoichiometry of complex physicochemical reactions, basic dynamic equations and an extreme principle were formulated. The meaning of discrete time and space in the proposed equations is discussed. Some results of numerical calculations are presented to demonstrate the potential of the proposed approach to the mathematical simulation of spatiotemporal physicochemical reaction dynamics.
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SreeHarsha, Nagaraja, Jagadeesh G. Hiremath, Swathi Chilukuri, et al. "An Approach to Enhance Dissolution Rate of Tamoxifen Citrate." BioMed Research International 2019 (January 20, 2019): 1–11. http://dx.doi.org/10.1155/2019/2161348.

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We tested the solubility and dissolution of tamoxifen citrate to ascertain the optimal conditions for faster dissolution. Using the solvent evaporation method and hydrophilic carriers, we formulated tamoxifen citrate (TC) that contained solid dispersions (SDs). We increased the solubility and dissolution rate of TC with a solid dispersion system that consisted of polyethylene glycol (PEG-6000), beta-cyclodextrin (β-CD), and a combination of carriers. Physicochemical characteristics of solubility (mg/ml) were found to be 0.987±0.04 (water), 1.324±0.05 (6.8pH PBS), and 1.156±0.03 (7.4 pH PBS) fo
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40

Bou, S. J. M. C., A. R. Connolly, and A. V. Ellis. "High-throughput physicochemical analysis of thermoresponsive polymers." Polymer Chemistry 9, no. 15 (2018): 1934–37. http://dx.doi.org/10.1039/c7py02066j.

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A novel high-throughput approach to rapidly measure the lower critical solution temperature, critical micelle concentration and critical micelle temperature of thermoresponsive polymers was developed and utilized to generate a physicochemical ‘MAP’ of a polymer series.
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Amalate, Ann Obuebite, and Onyeka Okwonna Obumneme. "Refinery effluent water treatment: An integrated approach." World Journal of Advanced Research and Reviews 18, no. 1 (2023): 057–62. https://doi.org/10.5281/zenodo.8166714.

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This study has successfully investigated the use of an integrated approach to refinery effluent water treatment. To achieve this, a multistage system was used for the treatment of refinery effluent water from Port Harcourt Refining Company, Rivers State Nigeria. The physicochemical and microbial properties of the treated effluent water were used to assess the efficacy of the treatment process. Properties investigated include temperature, pH, chlorine content, bacterial count, chemical and biological oxygen demand, dissolved oxygen, amount of oil and grease in the water, turbidity, and the amou
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Gugleva, Viliana, and Velichka Andonova. "Drug delivery to the brain – lipid nanoparticles-based approach." Pharmacia 70, no. 1 (2023): 113–20. http://dx.doi.org/10.3897/pharmacia.70.e98838.

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The complex structure of the human brain defines it as one of the most inaccessible organs in terms of drug delivery. The blood-brain barrier (BBB) represents a microvascular network involved in transporting substances between the blood and the central nervous system (CNS) – enabling the entry of nutrients and simultaneously restricting the influx of pathogens and toxins. However, its role as a protective shield for CNS also restricts drug access to the brain. Since many drugs cannot cross the BBB due to unsuitable physicochemical characteristics (i.e., high molecular weight, aqueous solubilit
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Gugleva, Viliana, and Velichka Andonova. "Drug delivery to the brain – lipid nanoparticles-based approach." Pharmacia 70, no. (1) (2023): 113–20. https://doi.org/10.3897/pharmacia.70.e98838.

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The complex structure of the human brain defines it as one of the most inaccessible organs in terms of drug delivery. The blood-brain barrier (BBB) represents a microvascular network involved in transporting substances between the blood and the central nervous system (CNS) – enabling the entry of nutrients and simultaneously restricting the influx of pathogens and toxins. However, its role as a protective shield for CNS also restricts drug access to the brain. Since many drugs cannot cross the BBB due to unsuitable physicochemical characteristics (i.e., high molecular weight, aqueous solubilit
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44

Ahmad, Tawseef, Gaganjot Gupta, Anshula Sharma, Baljinder Kaur, Abdulaziz Abdullah Alsahli, and Parvaiz Ahmad. "Multivariate Statistical Approach to Study Spatiotemporal Variations in Water Quality of aHimalayan Urban Fresh Water Lake." Water 12, no. 9 (2020): 2365. http://dx.doi.org/10.3390/w12092365.

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Physicochemical parameters determining Dal Lake water quality were evaluated at four different sites during 2016–2017 in four different seasons Spring (April), Summer (July), Autumn (October), and Winter (January). The observed physicochemical values were analyzed by statistical (discriminant analysis) and arithmetic (WQI) methods to ascertain sources and levels of pollution. Discriminant analysis helped to access the contribution of each physicochemical parameter in water quality in the context of sampling sites (spatial) and seasons (temporal) to discriminate pollution loading between sites
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45

K, Mohammed Murthuza, Surumbarkuzhali N, Lakshmi Narasimhan C, and Ravisankar R. "Using Magnetic Susceptibility to Assess Soil Pollution in the Tiruvannamalai District, Tamil Nadu with Statistical Approach." Indian Journal of Science and Technology 16, no. 12 (2023): 910–23. https://doi.org/10.17485/IJST/v16i12.2326.

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Abstract <strong>Objective:</strong>&nbsp;This study used magnetic susceptibility measurements and statistical methods to investigate soil pollution.&nbsp;<strong>Method:</strong>&nbsp;Using the grid approach, soil samples were collected in and around Tiruvannamalai district, Tamil Nādu. Standard procedures were used to determine the physicochemical parameters of soil samples such as the percentages of sand, silt and clay, EC and pH. A dual frequency susceptibility meter was used to assess the magnetic susceptibility of the soil samples collected at low-frequency (clf) and high-frequency (chf)
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46

Silva, Joana M., Sofia G. Caridade, Nuno M. Oliveira, Rui L. Reis, and João F. Mano. "Chitosan–alginate multilayered films with gradients of physicochemical cues." Journal of Materials Chemistry B 3, no. 22 (2015): 4555–68. http://dx.doi.org/10.1039/c5tb00082c.

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A new approach was used to create multilayered films with gradients of physicochemical properties. This approach shows promise for the development of other types of gradients, which will be useful to mimic extracellular architecture.
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Anand, Rachna, Arun Kumar, and Arun Nanda. "Pharmaceutical Co-Crystals - Design, Development and Applications." Drug Delivery Letters 10, no. 3 (2020): 169–84. http://dx.doi.org/10.2174/2210303109666191211145144.

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Background: Solubility and dissolution profile are the major factors which directly affect the biological activity of a drug and these factors are governed by the physicochemical properties of the drug. Crystal engineering is a newer and promising approach to improve physicochemical characteristics of a drug without any change in its pharmacological action through a selection of a wide range of easily available crystal formers. Objective: The goal of this review is to summarize the importance of crystal engineering in improving the physicochemical properties of a drug, methods of design, devel
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Andonegi, Mireia, Ainhoa Irastorza, Ander Izeta, Sara Cabezudo, Koro de la Caba, and Pedro Guerrero. "A Green Approach towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment." Polymers 12, no. 7 (2020): 1597. http://dx.doi.org/10.3390/polym12071597.

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Native collagen scaffolds were prepared in this work, in which both materials and environmental approaches were considered with the aim of providing a global strategy towards more sustainable biomaterials. From the environmental perspective, it is worth mentioning that acid and enzymatic treatments have been avoided to extract collagen, allowing the reduction in the use of resources, in terms of chemicals, energy, and time, and leading to a low environmental load of this step in all the impact categories under analysis. With the incorporation of chitosan into the scaffold-forming formulations,
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Thakur, Abhilash. "QSAR study on benzenesulfonamide ionization constant : physicochemical approach using surface tension." Arkivoc 2005, no. 14 (2005): 49–58. http://dx.doi.org/10.3998/ark.5550190.0006.e06.

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Zhou, Y. X., Q. Nie, Z. Z. Chen, and R. Liu. "Analysis of electrical tree ageing in silicone rubber by physicochemical approach." Journal of Physics: Conference Series 183 (August 1, 2009): 012013. http://dx.doi.org/10.1088/1742-6596/183/1/012013.

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