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1

Puhani, Patrick A. "Labour Mobility: An Adjustment Mechanism in Euroland? Empirical Evidence for Western Germany, France and Italy." German Economic Review 2, no. 2 (2001): 127–40. http://dx.doi.org/10.1111/1468-0475.00031.

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Abstract We evaluate whether labour mobility is likely to act as a sufficient adjustment mechanism in the face of asymmetric shocks in Euroland. As no adequate data on cross-border migration are available, migration elasticities within nation states (Western Germany, France and Italy) are estimated and interpreted as upper bounds for cross-border migration elasticities between European nation states. Labour mobility is highest in Germany, followed by France and Italy. However, the accommodation of a shock to unemployment by migration takes several years. We conclude that labour mobility is unl
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2

Esposito, Michele L., Janelle Jablonski, Allison Kras, Sara Krasney, and Navin K. Kapur. "Maximum level of mobility with axillary deployment of the Impella 5.0 is associated with improved survival." International Journal of Artificial Organs 41, no. 4 (2018): 236–39. http://dx.doi.org/10.1177/0391398817752575.

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Mobility is an important prognostic indicator for patients with cardiogenic shock. No studies have quantified peak mobility for patients with cardiogenic shock who are supported with the Impella 5.0 acute mechanical circulatory support device. The purpose of our study was to evaluate mobility levels among patients with cardiogenic shock being treated with an axillary Impella 5.0 pump. We retrospectively analyzed data from 19 patients receiving an Impella 5.0 device for cardiogenic shock at our institution from 2013 to 2016. We used the Johns Hopkins Highest Level of Mobility Scale to quantify
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3

Mandal, Biswajit. "Recessionary Shock, Capital Mobility and the Informal Sector." South Asia Economic Journal 17, no. 1 (2016): 149–62. http://dx.doi.org/10.1177/1391561415621828.

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4

Yuk, Sunwoo, Kiwon Choi, Sang-Geon Park, and Sukmin Lee. "A Study on the Reliability Test of a Lithium Battery in Medical Electric Wheelchairs for Vulnerable Drivers." Applied Sciences 9, no. 11 (2019): 2299. http://dx.doi.org/10.3390/app9112299.

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There are test items for lithium-ion batteries in reliability testing for automobiles and motorcycles, but equivalent test items have not yet been established for mobility scooters (also known as electronic wheelchairs). To evaluate the lithium-ion battery pack or system mounted on a mobility scooter, it is necessary to test vibrations and mechanical shock while driving, independent of tests for the lithium-ion battery cells. In an effort to meet this need, test profiles were established for mobility scooter lithium-ion batteries by performing on-road driving tests and mechanical shock tests.
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5

Bar, Daniel Z., Maya Davidovich, Ayelet T. Lamm, Hagit Zer, Katherine L. Wilson, and Yosef Gruenbaum. "BAF-1 mobility is regulated by environmental stresses." Molecular Biology of the Cell 25, no. 7 (2014): 1127–36. http://dx.doi.org/10.1091/mbc.e13-08-0477.

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Barrier to autointegration factor (BAF) is an essential component of the nuclear lamina that binds lamins, LEM-domain proteins, histones, and DNA. Under normal conditions, BAF protein is highly mobile when assayed by fluorescence recovery after photobleaching and fluorescence loss in photobleaching. We report that Caenorhabditis elegans BAF-1 mobility is regulated by caloric restriction, food deprivation, and heat shock. This was not a general response of chromatin-associated proteins, as food deprivation did not affect the mobility of heterochromatin protein HPL-1 or HPL-2. Heat shock also in
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6

Fisher, Mary C., Stephanie K. Moore, Sunny L. Jardine, James R. Watson, and Jameal F. Samhouri. "Climate shock effects and mediation in fisheries." Proceedings of the National Academy of Sciences 118, no. 2 (2021): e2014379117. http://dx.doi.org/10.1073/pnas.2014379117.

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Climate shocks can reorganize the social–ecological linkages in food-producing communities, leading to a sudden loss of key products in food systems. The extent and persistence of this reorganization are difficult to observe and summarize, but are critical aspects of predicting and rapidly assessing community vulnerability to extreme events. We apply network analysis to evaluate the impact of a climate shock—an unprecedented marine heatwave—on patterns of resource use in California fishing communities, which were severely affected through closures of the Dungeness crab fishery. The climate sho
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Dushchenko, Vladislav, Serhii Vorontsov, Vyacheslav Masliyev, et al. "Comparing the physical principles of action of suspension damping devices based on their influence on the mobility of wheeled vehicles." Eastern-European Journal of Enterprise Technologies 4, no. 5(112) (2021): 51–60. http://dx.doi.org/10.15587/1729-4061.2021.237312.

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This paper reports the comparison of two physical principles of action of suspension damping devices based on their influence on the mobility indicators for an 8×8 wheeled machine. A radical difference between these principles of action is the dependence of resistance forces on the speed of the relative movement of working bodies (internal friction: hydraulic shock absorbers) or on the relative movement of working bodies (external friction: friction shock absorbers). Widespread hydraulic shock absorbers have certain disadvantages that do not make it possible to further increase the mobility of
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8

Tsapenko, I. Р. "CROSS-BORDER POPULATION MOBILITY AMID AND AFTER THE PANDEMIC SHOCK." Social & labor researches 40, no. 3 (2020): 31–43. http://dx.doi.org/10.34022/2658-3712-2020-40-3-31-43.

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9

Martinez, J., J. Perez-Serrano, W. E. Bernadina, and F. Rodriguez-Caabeiro. "Expression of Hsp90, Hsp70 and Hsp60 in Trichinella species exposed to oxidative shock." Journal of Helminthology 76, no. 3 (2002): 217–23. http://dx.doi.org/10.1079/joh2002127.

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AbstractStress response and phosphorylation of heat shock proteins (HSPs) 60, 70 and 90 were studied in Trichinella nativa, T. nelsoni, T. pseudospiralis and T. spiralis larvae at 30-min intervals following exposure to 20, 100 and 200 mM H2O2. There was a time- and dose-dependent differential survival for the infective stage larvae (L1) of these four Trichinella species. Immunoblotting analysis revealed that constitutive Hsp60 and Hsp70, but not Hsp90, from test Trichinella species are constitutively phosphorylated on serine/threonine residues as they converted to forms with increased sodium d
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10

Cajone, F., M. Salina, and A. Benelli-Zazzera. "4-Hydroxynonenal induces a DNA-binding protein similar to the heat-shock factor." Biochemical Journal 262, no. 3 (1989): 977–79. http://dx.doi.org/10.1042/bj2620977.

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By using a gel mobility assay, we have shown that treatment of HeLa cells with 4-hydroxynonenal, a major product of the peroxidation of membrane lipids and an inducer of heat-shock proteins, has the same effect as heat shock in causing the appearance of a protein which binds to the sequence of DNA specific for the induction of heat-shock genes. Lipoperoxidation and heat exposure seem to share a common mechanism of specific gene activation.
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11

Gibot, Sébastien, Frédéric Massin, Aurélie Cravoisy, et al. "High-mobility group box 1 protein plasma concentrations during septic shock." Intensive Care Medicine 33, no. 8 (2007): 1347–53. http://dx.doi.org/10.1007/s00134-007-0691-2.

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12

Jerome, Joseph W., and Chi-Wang Shu. "The Response of the Hydrodynamic Model to Heat Conduction, Mobility, and Relaxation Expressions." VLSI Design 3, no. 2 (1995): 131–43. http://dx.doi.org/10.1155/1995/89680.

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We study simulations of then+-n-n+ diode, by means of higher moment models, derived from the Boltzmann equation. We emply such realistic assumptions as energy dependent mobility functions, with doping dependent low field mobility. It is known that a critical role is played in the hydrodynamic model by the heat conduction term. When the standard choice of the Wiedemann-Franz law is made for the conductivity, and constant low field mobility values are used, spurious overshoot is observed. Agreement with Monte-Carlo simulation in this regime has in the past been achieved by empirical modification
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Crawford, Jeremie J., Frannie Itzkow, Joanna MacLean, and Douglas B. Craig. "Conformational change in individual enzyme molecules." Biochemistry and Cell Biology 93, no. 6 (2015): 611–18. http://dx.doi.org/10.1139/bcb-2015-0099.

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Single β-galactosidase molecule assays were performed using a capillary electrophoresis based protocol, employing post-column laser-induced fluorescence detection. In a first set of experiments, the distribution of single β-galactosidase molecule catalytic rates and electrophoretic mobilities were determined from lysates of Escherichia coli strains containing deletions for different heat shock proteins and grown under normal and heat shock conditions. There was no clear observed pattern of effect of heat shock protein expression on these distributions. In a second set of experiments, individua
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14

Locke, M., E. G. Noble, R. M. Tanguay, M. R. Feild, S. E. Ianuzzo, and C. D. Ianuzzo. "Activation of heat-shock transcription factor in rat heart after heat shock and exercise." American Journal of Physiology-Cell Physiology 268, no. 6 (1995): C1387—C1394. http://dx.doi.org/10.1152/ajpcell.1995.268.6.c1387.

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Stress-induced transcriptional regulation of the heat-shock proteins (HSP) is mediated by activation and binding of the heat-shock transcription factors (HSF) to the heat-shock element (HSE). Given the similarities between the stressors known to activate the HSF in cultured cells and the physiological stresses known to occur during exercise, HSF activation was examined in the hearts from exercising animals. Sprague-Dawley rats (5 rats/group) were run on a treadmill (24 m/min) for either 0, 20, 40, or 60 min or to exhaustion (102 +/- 7 min). Protein extracts were assessed for HSF activation by
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15

Ombrellino, Michael, Haichao Wang, Michael S. Ajemian, et al. "Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock." Lancet 354, no. 9188 (1999): 1446–47. http://dx.doi.org/10.1016/s0140-6736(99)02658-6.

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16

Sauneuf, B., D. Grimaldi, C. Rousseau, J.-D. Chiche, C. Desgranges, and J.-P. Mira. "Naturally acquired anti-high mobility group box 1 antibodies during septic shock." Critical Care 13, Suppl 4 (2009): P55. http://dx.doi.org/10.1186/cc8125.

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17

Leonard, Tammy, Amy E. Hughes, and Sandi L. Pruitt. "Understanding How Low–Socioeconomic Status Households Cope with Health Shocks." ANNALS of the American Academy of Political and Social Science 669, no. 1 (2016): 125–45. http://dx.doi.org/10.1177/0002716216680989.

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Low–socioeconomic status (SES) households have little income or wealth to buffer against the negative impacts of adverse health events among adult household members. This research project links data from a nonprofit food distribution center, electronic medical records from a safety-net healthcare system, and publicly available residential appraisals for more than 3,000 households to provide insight into how low-SES households cope with health shocks experienced by resident adults. Three broad types of strategies are examined: changes in household structure, residential mobility, and use of soc
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18

Bakker, Jan David, Christopher Parsons, and Ferdinand Rauch. "Migration and Urbanization in Post-Apartheid South Africa." World Bank Economic Review 34, no. 2 (2019): 509–32. http://dx.doi.org/10.1093/wber/lhy030.

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Abstract Although Africa has experienced rapid urbanization in recent decades, little is known about the process of urbanization across the continent. This paper exploits a natural experiment, the abolition of South African pass laws, to explore how exogenous population shocks affect the spatial distribution of economic activity. Under apartheid, black South Africans were severely restricted in their choice of location, and many were forced to live in homelands. Following the abolition of apartheid they were free to migrate. Given a migration cost in distance, a town nearer to the homelands wi
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19

Konstantopoulou, Irene, Elena Drosopoulou, and Zacharias G. Scouras. "Variations in the heat-induced protein pattern of several Drosophila montium subgroup species (Diptera: Drosophilidae)." Genome 40, no. 1 (1997): 132–37. http://dx.doi.org/10.1139/g97-019.

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After temperature elevation, the newly synthesized polypeptides from several Drosophila montium subgroup species, of the melanogaster species group, were analyzed in denaturing acrylamide gels. The pattern obtained is characteristic of the heat shock response already documented for many other Drosophila species, although the relative electrophoretic mobility of the "small" heat shock proteins exhibits a species-specific pattern. Based on the above pattern, the montium species are placed in three distinct groups. The present data is consistent with that previously used to propose a northeast to
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Zatsepina, O. G., K. A. Ulmasov, S. F. Beresten, V. B. Molodtsov, S. A. Rybtsov, and M. B. Evgen'ev. "Thermotolerant desert lizards characteristically differ in terms of heat-shock system regulation." Journal of Experimental Biology 203, no. 6 (2000): 1017–25. http://dx.doi.org/10.1242/jeb.203.6.1017.

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We compare the properties and activation of heat-shock transcription factor (HSF1) and the synthesis of a major family of heat-shock proteins (HSP70) in lizard species inhabiting ecological niches with strikingly different thermal parameters. Under normal non-heat-shock conditions, all desert-dwelling lizard species studied so far differ from a northern, non-desert species (Lacerta vivipara) in the electrophoretic mobility and content of proteins constitutively bound to the regulatory heat-shock elements in the heat-shock gene promoter. Under these conditions, levels of activated HSF1 and of b
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21

Sobolev, Valeriy V., and S. M. Usherenko. "Formation of Chemical Elements under Superdeep Penetration of Lead Microparticles in Ferrous Target." Advanced Materials Research 47-50 (June 2008): 25–28. http://dx.doi.org/10.4028/www.scientific.net/amr.47-50.25.

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The results of experimental research of physical and chemical transformations in a ferrous target, caused by intensive deformation mobility of its structural elements for times of shock-wave treatment (∼10–3 sec), at simultaneous development of process of superdeep penetration of lead microparticles are represented.
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22

Batardière, Marie-Thérèse, Marta Giralt, Catherine Jeanneau, Florence Le-Baron-Earle, and Veronica O’Regan. "Promoting intercultural awareness among European university students via pre-mobility virtual exchanges." Journal of virtual exchange 2, no. 1 (2019): 1–6. http://dx.doi.org/10.14705/rpnet.2019.jve.4.

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For more than 30 years, the Erasmus programme has given thousands of higher education students throughout Europe the chance to live and study abroad. For many, this sojourn in a foreign country is an extraordinary learning experience which enriches their language and (inter)cultural learning process. However, for others, this opportunity is undermined by cultural shock or lack of preparation...
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Tsan, Min-Fu. "Heat shock proteins and high mobility group box 1 protein lack cytokine function." Journal of Leukocyte Biology 89, no. 6 (2011): 847–53. http://dx.doi.org/10.1189/jlb.0810471.

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24

Barchetta, Sabrina, Antonietta La Terza, Patrizia Ballarini, Sandra Pucciarelli, and Cristina Miceli. "Combination of Two Regulatory Elements in the Tetrahymena thermophila HSP70-1 Gene Controls Heat Shock Activation." Eukaryotic Cell 7, no. 2 (2007): 379–86. http://dx.doi.org/10.1128/ec.00221-07.

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ABSTRACT The induction of heat shock genes (HSPs) is thought to be primarily regulated by heat shock transcription factors (HSFs), which bind target sequences on HSP promoters, called heat shock elements (HSEs). In this study, we investigated the 5′ untranslated regions of the Tetrahymena thermophila HSP70-1 gene, and we found, in addition to the canonical and divergent HSEs, multiple sets of GATA elements that have not been reported previously in protozoa. By means of in vivo analysis of a green fluorescent protein reporter transgene driven by the HSP70-1 promoter, we demonstrate that HSEs do
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Bashirova, K. I., and C. I. Mikhaylenko. "Shock wave reflection from a layer of a finely dispersed medium with low concentrations." Multiphase Systems 14, no. 4 (2019): 279–83. http://dx.doi.org/10.21662/mfs2019.4.036.

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The paper investigates the propagation of a shock wave when interacting with a loosely packed granular medium. The continuous two-phase mathematical model presented in this work allows one to numerically describe the propagation of a shock wave in the channel of a shock tube, the achievement of a layer of granular filling by the shock wave, and the reflection of the wave. It was shown that the granular medium partially transmits the shock wave, but mostly corresponds to it. This reflection differs from the reflection of a shock wave from a solid wall. The nature of the reflection of the shock
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Karn, Heather, Nick Ovsenek, and John J. Heikkila. "Examination of the DNA sequence-specific binding properties of heat shock transcription factor in Xenopus laevis embryos." Biochemistry and Cell Biology 70, no. 10-11 (1992): 1006–13. http://dx.doi.org/10.1139/o92-144.

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The binding of heat shock transcription factor (HSF) to the heat shock element (HSE) is necessary for transcriptional activation of eukaryotic heat shock protein (HSP) genes. The properties of Xenopus embryo HSF were examined by DNA mobility shift analysis employing a synthetic oligonucleotide corresponding to the proximal HSE in the promoter of the Xenopus HSP70B gene. Heat shock induced activation of HSF binding in Xenopus neurulae was not affected by an inhibition of protein synthesis, indicating that the mode of activation may be posttranslational. Also, while HSF binding was activated in
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Islam, Marjan, David Nesheim, Samuel Acquah, et al. "Right Heart Thrombi: Patient Outcomes by Treatment Modality and Predictors of Mortality: A Pooled Analysis." Journal of Intensive Care Medicine 34, no. 11-12 (2018): 930–37. http://dx.doi.org/10.1177/0885066618808193.

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Rationale: Right heart thrombi (RiHT) is characterized by the presence of thrombus within the right atrium or right ventricle (RV). Current literature suggests pulmonary embolism (PE) with RiHT carries a high mortality. Guidelines lack recommendations in managing RiHT. We created a pooled analysis on RiHT and report on our institutional experience in managing RiHT. We aimed to evaluate whether patient characteristics and differing treatment modalities predict mortality. Methods: We created a pooled analysis of case reports and series of patients with RiHT and PE between January 1956 and 2017.
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Mosser, D. D., N. G. Theodorakis, and R. I. Morimoto. "Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells." Molecular and Cellular Biology 8, no. 11 (1988): 4736–44. http://dx.doi.org/10.1128/mcb.8.11.4736.

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Activation of human heat shock gene transcription by heat shock, heavy metal ions, and amino acid analogs required the heat shock element (HSE) in the HSP70 promoter. Both heat shock- and metal ion-induced HSP70 gene transcription occurred independently of protein synthesis, whereas induction by amino acid analogs required protein synthesis. We identified a HSE-binding activity from control cells which was easily distinguished by a gel mobility shift assay from the stress-induced HSE-binding activity which appeared following heat shock or chemically induced stress. The kinetics of HSP70 gene t
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Mosser, D. D., N. G. Theodorakis, and R. I. Morimoto. "Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells." Molecular and Cellular Biology 8, no. 11 (1988): 4736–44. http://dx.doi.org/10.1128/mcb.8.11.4736-4744.1988.

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Activation of human heat shock gene transcription by heat shock, heavy metal ions, and amino acid analogs required the heat shock element (HSE) in the HSP70 promoter. Both heat shock- and metal ion-induced HSP70 gene transcription occurred independently of protein synthesis, whereas induction by amino acid analogs required protein synthesis. We identified a HSE-binding activity from control cells which was easily distinguished by a gel mobility shift assay from the stress-induced HSE-binding activity which appeared following heat shock or chemically induced stress. The kinetics of HSP70 gene t
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Sistonen, L., K. D. Sarge, B. Phillips, K. Abravaya, and R. I. Morimoto. "Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells." Molecular and Cellular Biology 12, no. 9 (1992): 4104–11. http://dx.doi.org/10.1128/mcb.12.9.4104.

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Hemin induces nonterminal differentiation of human K562 erythroleukemia cells, which is accompanied by the expression of certain erythroid cell-specific genes, such as the embryonic and fetal globins, and elevated expression of the stress genes hsp70, hsp90, and grp78/BiP. Previous studies revealed that, as during heat shock, transcriptional induction of hsp70 in hemin-treated cells is mediated by activation of heat shock transcription factor (HSF), which binds to the heat shock element (HSE). We report here that hemin activates the DNA-binding activity of HSF2, whereas heat shock induces pred
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Sistonen, L., K. D. Sarge, B. Phillips, K. Abravaya, and R. I. Morimoto. "Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells." Molecular and Cellular Biology 12, no. 9 (1992): 4104–11. http://dx.doi.org/10.1128/mcb.12.9.4104-4111.1992.

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Hemin induces nonterminal differentiation of human K562 erythroleukemia cells, which is accompanied by the expression of certain erythroid cell-specific genes, such as the embryonic and fetal globins, and elevated expression of the stress genes hsp70, hsp90, and grp78/BiP. Previous studies revealed that, as during heat shock, transcriptional induction of hsp70 in hemin-treated cells is mediated by activation of heat shock transcription factor (HSF), which binds to the heat shock element (HSE). We report here that hemin activates the DNA-binding activity of HSF2, whereas heat shock induces pred
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ALFIERI, Roberta, Pier Giorgio PETRONINI, Simona URBANI, and Angelo F. BORGHETTI. "Activation of heat-shock transcription factor 1 by hypertonic shock in 3T3 cells." Biochemical Journal 319, no. 2 (1996): 601–6. http://dx.doi.org/10.1042/bj3190601.

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The exposure of 3T3 cells to a medium made hypertonic by the addition of NaCl induced activation of a heat-shock transcription factor (HSF). This activation, as monitored by gel-mobility-shift assays, occurred within 10 min of hypertonic shock and was dose-dependent in relation to the osmotic strength of the medium up to 0.7 osM. Competition analysis indicated that the effect of hypertonic shock on HSF binding activity was specific. The magnitude of the heat-shock element (HSE)-HSF binding induced by incubating the cells in a 0.7 osM medium was comparable in intensity and time course with that
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Semenikhin, Ihor, Victor Ryzhii, Ekaterina Vostrikova, and Andrej Ivanov. "Electrical excitation of shock and soliton-like waves in high-electron-mobility transistor structures." physica status solidi (c) 5, no. 1 (2008): 61–65. http://dx.doi.org/10.1002/pssc.200776503.

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Caliendo, Lorenzo, Maximiliano Dvorkin, and Fernando Parro. "Trade and Labor Market Dynamics: General Equilibrium Analysis of the China Trade Shock." Econometrica 87, no. 3 (2019): 741–835. http://dx.doi.org/10.3982/ecta13758.

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We develop a dynamic trade model with spatially distinct labor markets facing varying exposure to international trade. The model captures the role of labor mobility frictions, goods mobility frictions, geographic factors, and input‐output linkages in determining equilibrium allocations. We show how to solve the equilibrium of the model and take the model to the data without assuming that the economy is at a steady state and without estimating productivities, migration frictions, or trade costs, which can be difficult to identify. We calibrate the model to 22 sectors, 38 countries, and 50 U.S.
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Gertsriken, D. S., A. M. Husak, V. F. Mazanko, and S. Ye Bogdanov. "The deformation rate, atomic mobility and mechanical properties of metals." Metaloznavstvo ta obrobka metalìv 97, no. 1 (2021): 28–37. http://dx.doi.org/10.15407/mom2021.01.028.

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The dependences of diffusion coefficients in metals with different crystal lattice (b.c.c., f.c.c., h.c.p., b.c.t.), subjected to pulse effects by different types of processing in a wide range of strain rates (10-2 - 106 s-1) without heating and at T < 0,5 Tpl. studied by m ethods based on the use of radioactive indicators 55Fe, 95Nb, 60Co, 65Zn, 63Ni, 26Al, 44Ti (layer-by-layer radiometric analysis of residual integral activity, macro- and microautoradiography). Used such types of processing as ultrasonic shock treatment, diffusion welding, shock load, magnetic pulse processing, etc. On th
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Hitraya, E. G., J. Varga, and S. A. Jimenez. "Heat shock of human synovial and dermal fibroblasts induces delayed up-regulation of collagenase-gene expression." Biochemical Journal 308, no. 3 (1995): 743–47. http://dx.doi.org/10.1042/bj3080743.

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We investigated the effect of heat shock on the expression of the collagenase gene in normal human synovial and dermal fibroblasts. Heat shock (42-44 degrees C for 1 h) caused a marked increase in heat-shock protein 70 (HSP-70) mRNA levels, followed by a delayed increase in collagenase mRNA levels, in both cell types. Pretreatment with cycloheximide had no effect on the heat-shock-induced increase in HSP-70 mRNA expression, but abrogated the induction of collagenase mRNA during the recovery. To study the mechanisms of collagenase-gene induction by heat shock, the transcriptional activity of a
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Gallo, G. J., T. J. Schuetz, and R. E. Kingston. "Regulation of heat shock factor in Schizosaccharomyces pombe more closely resembles regulation in mammals than in Saccharomyces cerevisiae." Molecular and Cellular Biology 11, no. 1 (1991): 281–88. http://dx.doi.org/10.1128/mcb.11.1.281.

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The heat shock response appears to be universal. All eucaryotes studied encode a protein, heat shock factor (HSF), that is believed to regulate transcription of heat shock genes. This protein binds to a regulatory sequence, the heat shock element, that is absolutely conserved among eucaryotes. We report here the identification of HSF in the fission yeast Schizosaccharomyces pombe. HSF binding was not observed in extracts from normally growing S. pombe (28 degrees C) but was detected in increasing amounts as the temperature of heat shock increased between 39 and 45 degrees C. This regulation is
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38

Gallo, G. J., T. J. Schuetz, and R. E. Kingston. "Regulation of heat shock factor in Schizosaccharomyces pombe more closely resembles regulation in mammals than in Saccharomyces cerevisiae." Molecular and Cellular Biology 11, no. 1 (1991): 281–88. http://dx.doi.org/10.1128/mcb.11.1.281-288.1991.

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The heat shock response appears to be universal. All eucaryotes studied encode a protein, heat shock factor (HSF), that is believed to regulate transcription of heat shock genes. This protein binds to a regulatory sequence, the heat shock element, that is absolutely conserved among eucaryotes. We report here the identification of HSF in the fission yeast Schizosaccharomyces pombe. HSF binding was not observed in extracts from normally growing S. pombe (28 degrees C) but was detected in increasing amounts as the temperature of heat shock increased between 39 and 45 degrees C. This regulation is
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39

Salazar Castillo, Rodrigo O., Sterre F. Ter Haar, Christopher G. Ponners, Martijn Bos, and William Rossen. "Fractional-Flow Theory for Non-Newtonian Surfactant-Alternating-Gas Foam Processes." Transport in Porous Media 131, no. 2 (2019): 399–426. http://dx.doi.org/10.1007/s11242-019-01351-6.

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Abstract Foam can improve sweep efficiency in gas-injection-enhanced oil recovery. Surfactant-alternating-gas (SAG) is a favored method of foam injection. Laboratory data indicate that foam can be non-Newtonian at low water fractional flow fw, and therefore during gas injection in a SAG process. We investigate the implications of this finding for mobility control and injectivity, by extending fractional-flow theory to gas injection in a non-Newtonian SAG process in radial flow. We make most of the standard assumptions of fractional-flow theory (incompressible phases, one-dimensional displaceme
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40

Li, Gefeng, Imtiaz S. Ali, and R. William Currie. "Insulin induces myocardial protection and Hsp70 localization to plasma membranes in rat hearts." American Journal of Physiology-Heart and Circulatory Physiology 291, no. 4 (2006): H1709—H1721. http://dx.doi.org/10.1152/ajpheart.00201.2006.

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Insulin induces the expression of the 70-kDa heat shock protein (Hsp70) in rat hearts. In this study, we examined insulin- and heat shock-treated hearts for improved contractile recovery after 30 min of ischemia, activation of the heat shock transcription factor, and localization of the Hsp70 in relation to dystrophin and α-tubulin. Adult male Sprague-Dawley rats were assigned to groups: 1) control, 2) sham control, 3) insulin injected (200 μU/g body wt), 4) heat shock treated (core body temperature 42°C for 15 min), and 5) heat shock and insulin treated. Six hours later, hearts were isolated
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41

Toger, Marina, Karima Kourtit, Peter Nijkamp, and John Östh. "Mobility during the COVID-19 Pandemic: A Data-Driven Time-Geographic Analysis of Health-Induced Mobility Changes." Sustainability 13, no. 7 (2021): 4027. http://dx.doi.org/10.3390/su13074027.

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The COVID-19 pandemic has profoundly affected the spatial mobility of a major part of the population in many countries. For most people, this was an extremely disruptive shock, resulting in loss of income, social contact and quality of life. However, forced to reduce human physical interaction, most businesses, individuals and households developed new action lines and routines, and were gradually learning to adapt to the new reality. Some of these changes might result in long-term changes in opportunity structures and in spatial preferences for working, employment or residential location choic
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42

Kalyan, Shirin, and Anthony W. Chow. "Staphylococcal Toxic Shock Syndrome Toxin-1 Induces the Translocation and Secretion of High Mobility Group-1 Protein from Both Activated T Cells and Monocytes." Mediators of Inflammation 2008 (2008): 1–7. http://dx.doi.org/10.1155/2008/512196.

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High mobility group box-1 (HMGB-1) is a DNA-binding protein secreted by activated monocytes and has been identified as a key late mediator of endotoxic shock. We investigated the regulation of HMGB-1 in human peripheral blood mononuclear cells (PBMCs) following stimulation with the staphylococcal superantigen, toxic shock syndrome toxin-1 (TSST-1), and found that TSST-1, like LPS, induced the secretion of HMGB-1 from human PBMC. However, unlike monocyte-driven sepsis caused by endotoxin, translocation and secretion of HMGB-1 mediated by TSST-1 was dependent on the presence of both activated T
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43

Lemos, Sara, and Jonathan Portes. "New Labour? The Effects of Migration from Central and Eastern Europe on Unemployment and Wages in the UK." B.E. Journal of Economic Analysis & Policy 14, no. 1 (2013): 299–338. http://dx.doi.org/10.1515/bejeap-2013-0065.

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Abstract The UK was one of only three countries that granted free movement of workers to accession nationals following the enlargement of the European Union in May 2004. The resulting migration inflow, which was substantially larger and faster than anticipated, arguably corresponds more closely to an exogenous supply shock than most migration shocks studied in the literature. We evaluate the impact of this migration inflow – one of the largest in British history – on the UK labour market. We use new monthly micro-level data and an empirical approach that investigates which of several particula
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44

Pugeat, M., A. Bonneton, D. Perrot, et al. "Decreased immunoreactivity and binding activity of corticosteroid-binding globulin in serum in septic shock." Clinical Chemistry 35, no. 8 (1989): 1675–79. http://dx.doi.org/10.1093/clinchem/35.8.1675.

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Abstract To investigate the mechanism(s) responsible for the depletion of corticosteroid-binding globulin (CBG) activity in serum in septic shock, we developed a radioimmunoassay (RIA) for human CBG, using a monospecific antiserum to human CBG raised in rabbits. CBG was purified from pooled human serum by precipitation with ammonium sulfate and successive affinity chromatography treatments on corticosterone-Sepharose and concanavalin A-Sepharose. Final purification was achieved by HPLC on a diethylaminoethyl-PW (polymer matrix) ion-exchange column. Typical standard curves established for the C
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45

Wu, B., C. Hunt, and R. Morimoto. "Structure and expression of the human gene encoding major heat shock protein HSP70." Molecular and Cellular Biology 5, no. 2 (1985): 330–41. http://dx.doi.org/10.1128/mcb.5.2.330.

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We have cloned a human gene encoding the 70,000-dalton heat shock protein (HSP70) from a human genomic library, using the Drosophila HSP70 gene as a heterologous hybridization probe. The human recombinant clone hybridized to a 2.6-kilobase polyadenylated mRNA from HeLa cells exposed to 43 degrees C for 2 h. The 2.6-kilobase mRNA was shown to direct the translation in vitro of a 70,000-dalton protein similar in electrophoretic mobility to the HSP70 synthesized in vivo. From the analysis of S1 nuclease-resistant mRNA-DNA hybrids, the HSP70 gene appears to be transcribed as an uninterrupted mRNA
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46

Wu, B., C. Hunt, and R. Morimoto. "Structure and expression of the human gene encoding major heat shock protein HSP70." Molecular and Cellular Biology 5, no. 2 (1985): 330–41. http://dx.doi.org/10.1128/mcb.5.2.330-341.1985.

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We have cloned a human gene encoding the 70,000-dalton heat shock protein (HSP70) from a human genomic library, using the Drosophila HSP70 gene as a heterologous hybridization probe. The human recombinant clone hybridized to a 2.6-kilobase polyadenylated mRNA from HeLa cells exposed to 43 degrees C for 2 h. The 2.6-kilobase mRNA was shown to direct the translation in vitro of a 70,000-dalton protein similar in electrophoretic mobility to the HSP70 synthesized in vivo. From the analysis of S1 nuclease-resistant mRNA-DNA hybrids, the HSP70 gene appears to be transcribed as an uninterrupted mRNA
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47

Toma, A., T. Cichon, R. Smolarczyk, W. Widlak, and N. Vydra. "224 Heat Shock Transcription Factor 1 (HSF1) Enhances Mobility of Mouse Melanoma B16(F10) Cells." European Journal of Cancer 48 (July 2012): S54—S55. http://dx.doi.org/10.1016/s0959-8049(12)70919-x.

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48

Bonaccorsi, Giovanni, Francesco Pierri, Matteo Cinelli, et al. "Economic and social consequences of human mobility restrictions under COVID-19." Proceedings of the National Academy of Sciences 117, no. 27 (2020): 15530–35. http://dx.doi.org/10.1073/pnas.2007658117.

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In response to the coronavirus disease 2019 (COVID-19) pandemic, several national governments have applied lockdown restrictions to reduce the infection rate. Here we perform a massive analysis on near–real-time Italian mobility data provided by Facebook to investigate how lockdown strategies affect economic conditions of individuals and local governments. We model the change in mobility as an exogenous shock similar to a natural disaster. We identify two ways through which mobility restrictions affect Italian citizens. First, we find that the impact of lockdown is stronger in municipalities w
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49

Hosokawa, N., K. Hirayoshi, H. Kudo, et al. "Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids." Molecular and Cellular Biology 12, no. 8 (1992): 3490–98. http://dx.doi.org/10.1128/mcb.12.8.3490.

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Transcriptional activation of human heat shock protein (HSP) genes by heat shock or other stresses is regulated by the activation of a heat shock factor (HSF). Activated HSF posttranslationally acquires DNA-binding ability. We previously reported that quercetin and some other flavonoids inhibited the induction of HSPs in HeLa and COLO 320DM cells, derived from a human colon cancer, at the level of mRNA accumulation. In this study, we examined the effects of quercetin on the induction of HSP70 promoter-regulated chloramphenicol acetyltransferase (CAT) activity and on the binding of HSF to the h
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50

Hosokawa, N., K. Hirayoshi, H. Kudo, et al. "Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids." Molecular and Cellular Biology 12, no. 8 (1992): 3490–98. http://dx.doi.org/10.1128/mcb.12.8.3490-3498.1992.

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Transcriptional activation of human heat shock protein (HSP) genes by heat shock or other stresses is regulated by the activation of a heat shock factor (HSF). Activated HSF posttranslationally acquires DNA-binding ability. We previously reported that quercetin and some other flavonoids inhibited the induction of HSPs in HeLa and COLO 320DM cells, derived from a human colon cancer, at the level of mRNA accumulation. In this study, we examined the effects of quercetin on the induction of HSP70 promoter-regulated chloramphenicol acetyltransferase (CAT) activity and on the binding of HSF to the h
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