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Thematische Bibliographien / Single Kidney / Zeitschriftenartikel

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Zeitschriftenartikel zum Thema „Single Kidney“

Autor: Grafiati

Veröffentlicht am 5. Juni 2025

Zuletzt aktualisiert am 2. August 2025

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1

Chang, Yoon-Jung, Samuel Simpson, Megan Charette, and Obi Ekwenna. "A Single-Center Experience of En Bloc vs. Single Renal Transplantation on Adult Recipients." Transplantology 6, no. 1 (2025): 7. https://doi.org/10.3390/transplantology6010007.

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Background/Objectives: While there are several debates on en bloc renal transplants and pediatric donors regarding the efficacy and concern for renal mass, multiple studies have supported the notion that transplanting pediatric en bloc kidneys produces comparable results in contrast to single kidneys from living or deceased donors. Methods: This case series included a retrospective analysis of a university medical center, primarily focused on comparing the post-operative outcomes between recipients of pediatric and adult en bloc kidneys, which are horseshoe kidneys, from deceased donors and re

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Gruessner, Rainer W. G., Arthur J. Matas, Goncal Lloveras, et al. "A comparison of single and double pediatric cadaver donor kidneys for transplantation." Clinical Transplantation 3, no. 4 (1989): 209–14. http://dx.doi.org/10.1111/j.1399-0012.1989.tb00184.x.

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Use of pediatric cadaver kidneys for transplantation is controversial; reports of outcome following pediatric donor transplantation have shown either similar results or worse results than when adult donors are used. Two techniques have been proposed for use of pediatric donor kidneys ‐ transplantation of a single kidney, or transplantation of both kidneys with a common aorta and cava to a single recipient. Single kidney transplants make optimum use of the donor pool; double transplants provide increased renal mass and therefore more functional reserve in the early posttransplant period. No stu

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V. M. Monastyrsʹkyy. "CHARACTERISTICS OF THE KIDNEY PARAMETERS ACCORDING TO THE DATA OF MAGNETIC RESONANCE IMAGING OF PATIENTS WITH UROLITHIASIS IN PERSONS WITH A SINGLE KIDNEY." Clinical anatomy and operative surgery 17, no. 3 (2018): 38–43. http://dx.doi.org/10.24061/1727-0847.17.3.2018.6.

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Urolithiasis is one of the most common diseases of the kidneys and urinary tract. The purpose of the study is to compare the size of a single kidney in patients with urolithiasis with parameters of the kidneys of patients with two kidneys who don’t have any diseases of the kidneys and urinary tract. A comprehensive examination of 84 patients with urolithiasis and single kidney and 65 patients with two kidneys who didn’t have any kidney and urinary tract diseases were conducted. The research was carried out on a magnetic resonance tomography Philips Intera-1,5T (standard magnetic resonance prot

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Jiang, Mengmeng, Haide Chen, and Guoji Guo. "Studying Kidney Diseases at the Single-Cell Level." Kidney Diseases 7, no. 5 (2021): 335–42. http://dx.doi.org/10.1159/000517130.

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<b><i>Background:</i></b> The kidney is a highly complex organ that performs diverse functions that are essential for health. Kidney disease occurs when the kidneys are damaged and fail to function properly. Single-cell analysis is a powerful technology that provides unprecedented insights into normal and abnormal kidney cell types and will transform our understanding of the mechanism underlying common kidney diseases. <b><i>Summary:</i></b> Our understanding of kidney disease pathogenesis is limited by the incomplete molecular characterization o

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Ibrahim, Maria, George H. B. Greenhall, Dominic M. Summers, et al. "Utilization and Outcomes of Single and Dual Kidney Transplants from Older Deceased Donors in the United Kingdom." Clinical Journal of the American Society of Nephrology 15, no. 9 (2020): 1320–29. http://dx.doi.org/10.2215/cjn.02060220.

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Background and objectivesKidneys from elderly deceased donors are often discarded after procurement if the expected outcomes from single kidney transplantation are considered unacceptable. An alternative is to consider them for dual kidney transplantation. We aimed to examine the utilization of kidneys from donors aged ≥60 years in the United Kingdom and compare clinical outcomes of dual versus single kidney transplant recipients.Design, setting, participants, & measurementsData from the United Kingdom Transplant Registry from 2005 to 2017 were analyzed. We examined utilization rates of ki

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Altshuler, Peter J., Adam S. Bodzin, Kenneth A. Andreoni, et al. "Deceased Donor Renal Allograft Utility in Adult Single and Multi-organ Transplantation in the United States." Transplantation Direct 11, no. 1 (2024): e1744. https://doi.org/10.1097/txd.0000000000001744.

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Background. Deceased donor multiorgan transplants utilizing kidneys (MOTs) can improve outcomes for multiorgan recipients but reduces kidneys for chronic renal failure patients. Methods. We reviewed the Organ Procurement and Transplantation Network database from 2015 through 2019, for adult deceased donor kidney transplants. Recipients were classified as kidney transplant alone (KTA) (n = 62,252) or MOTs pancreas-kidney, simultaneous pancreas-kidney (n = 3,976), liver-kidney, simultaneous liver-kidney (n = 3,212), heart-kidney, simultaneous heart-kidney (n = 808), and “other”-kidney, simultane

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Shah, Harda, and Nehal Shah. "Pulmonary functions in kidney transplant recipients: Single centre observational study." International Journal of Physiotherapy and Research 9, no. 5 (2021): 3986–91. http://dx.doi.org/10.16965/ijpr.2021.167.

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Background: Kidney transplantation in India is steadily increasing with advancement in medicines and surgical expertise. Subjects with kidney disease have spectrum of pulmonary pathologies but little is known regarding status on pulmonary function after kidney transplantation. Method: 149 kidney transplant recipients between 18 to 60 years of age, having stable graft function and more than 6months of post-transplant duration were included in the study. Forced vital capacity (FVC), forced expiratory volume in first second (FEV1), the ratio of FEV1/FVC and peak expiratory flow rate (PEFR) were e

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Emegoakor, Adaobi Chiazor, Munachi Onyebuchi Nwabunike, Onyekachi Amos Onu, et al. "Fused Left Supernumerary Kidney with Single Blood Supply and Ureter." Journal of Radiation Medicine in the Tropics 4, no. 2 (2023): 58–61. http://dx.doi.org/10.4103/jrmt.jrmt_3_23.

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Abstract Supernumerary kidneys, also known as accessory kidneys, refer to the presence of more than two kidneys. It is a rare congenital abnormality of the urinary system with only a few cases reported so far in literature. The extra kidney commonly has its own collecting system, blood supply, and well-defined encapsulated tissue. It may or may not be fused to the other kidneys by fibrous tissue or a parenchymal bridge. Imaging for vague abdominal symptoms may result in an incidental finding of the rare anatomical variant which may indicate an adjustment of routine physical activities to avoid

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Ismail, Omar Mobeen, Mahmud Saedon, Videha Sharma, Argiris Asderakis, and Titus Augustine. "Staggered Dual Kidney Transplantation." Progress in Transplantation 31, no. 3 (2021): 263–66. http://dx.doi.org/10.1177/15269248211024606.

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We describe a case where a patient received a successful dual kidney transplantation in a staggered fashion. Two kidneys from a deceased donor were accepted for 2 separate primary intended recipients, however, due to unforeseen circumstances, both kidneys were eventually transplanted in a staggered fashion into an alternate single recipient. The intention behind this method was to enhance the patient’s renal function and to prevent the wastage of a kidney. Despite the significantly prolonged cold ischemia times, the recipient has excellent dual graft function after 3 years. The positive outcom

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Monastirskiy, V. M., and V. I. Pivtorak. "MORPHOFUNCTIONAL STATE OF A SINGLE KIDNEY REMAINING AFTER CONTRALATERAL NEPHRECTOMY (LITERATURE REVIEW AND OWN RESEARCH)." Reports of Vinnytsia National Medical University 22, no. 4 (2018): 743–51. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(4)-30.

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The study of the structural and functional basis of compensatory and adaptive processes in the kidneys is one of the fundamental problems of biology and medicine. The purpose of the work: to highlight modern views on the question of compensation of structure and function in the loss of one kidney. There is a discussion about the mechanisms and patterns of development of compensatory processes in the surgical removal of one kidney, as well as at the birth of a child with kidney agenesis in the scientific literature. Previously, it was believed that the kidney, after it was formed and grown, doe

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Al-Toma, Riyadh R. "Safety and efficacy of percutaneous nephrolithotomy in patients with a single functioning kidney compared to patients with bilateral functioning kidneys." F1000Research 8 (May 28, 2019): 742. http://dx.doi.org/10.12688/f1000research.19259.1.

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Background: Renal stones for patients with a single functioning kidney are considered a great challenge for urologists. Different treatment modalities are used for those with a single functioning kidney, including shock wave lithotripsy, retrograde intra-renal surgery and percutaneous nephrolithotomy (PCNL). This study aimed to compare the effectiveness and safety outcomes of PCNL in patients with a single kidney compared to those with bilateral kidneys. Methods: A prospective comparative study conducted in Urology department of Safeer Al-Imam Al-Hussein hospital in Karbala city-Iraq through t

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Quaresma, Vasco, Margarida Carneiro, Lorenzo Marconi, et al. "Non-Inferiority of Dual Kidney Transplantation: A Retrospective Matched Study." Transplantology 6, no. 1 (2025): 5. https://doi.org/10.3390/transplantology6010005.

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Background/Objectives: Dual kidney transplantation is a potential technique to reduce the number of discarded kidneys from expanded-criteria donors. Due to allegedly poor outcomes, some centres have abandoned this technique. We aimed to compare dual versus single kidney transplantation. Methods: This retrospective, propensity score-matched, non-inferiority study compared dual kidney transplantation and single kidney transplantation results. Matching was performed based on key donor characteristics, including age, sex, serum creatinine levels, and cause of death due to cerebrovascular accident.

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Chan, Katrina, and Xiaogang Li. "Current Epigenetic Insights in Kidney Development." Genes 12, no. 8 (2021): 1281. http://dx.doi.org/10.3390/genes12081281.

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The kidney is among the best characterized developing tissues, with the genes and signaling pathways that regulate embryonic and adult kidney patterning and development having been extensively identified. It is now widely understood that DNA methylation and histone modification patterns are imprinted during embryonic development and must be maintained in adult cells for appropriate gene transcription and phenotypic stability. A compelling question then is how these epigenetic mechanisms play a role in kidney development. In this review, we describe the major genes and pathways that have been l

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Yao, Liyu, Honglan Zhou, Yuantao Wang, et al. "Hypothermic Machine Perfusion in DCD Kidney Transplantation: A Single Center Experience." Urologia Internationalis 96, no. 2 (2015): 148–51. http://dx.doi.org/10.1159/000431025.

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Introduction: Donation after cardiac death (DCD) began in 2011 after the program hosted by the First Affiliated Hospital of Sun Yat-sen University in China. The aim of this study is to report on our experience regarding the method of preserving donated kidneys for DCD kidney transplantation. Material and Methods: A total of 37 donors and 73 primary kidney transplant recipients during the period 2011-2014 in the Urology Center of the First Hospital of Jilin University were enrolled in the study. Recipients were assigned to traditional static cold storage (SCS) group and hypothermic machine perf

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Adhikari, Kapil, Niraj Regmi, Karun Devkota, and Sapana Koirala. "The Impact of Pelvicalyceal System Anatomy on Stone Formation in Patients with Single Lower Pole Calyceal Stone on Computed Tomography Urography." Journal of Nepal Health Research Council 22, no. 01 (2024): 91–95. http://dx.doi.org/10.33314/jnhrc.v22i01.4330.

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Background: To compare various lower pole pelvicalyceal anatomical factors of stone bearing kidney with contralateral normal kidneys and determine whether these factors predispose to stone formation in one kidney. Methods: A descriptive study was done with Computed Tomography of 54 patients with solitary lower pole calculus in one kidney and normal contralateral kidney were included. Various lower pole pelvicalyceal anatomical factors like infundibulopelvic angle, infundibular width, infundibular length and calyceopelvic height of both stone bearing and contralateral kidneys were measured and

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Ruff, Tim, K. Sudhakar Reddy, Thomas D. Johnston, et al. "Transplantation of Pediatric En Bloc Cadaver Kidneys into Adult Recipients: A Single-Center Experience." American Surgeon 68, no. 10 (2002): 857–59. http://dx.doi.org/10.1177/000313480206801004.

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Faced with an extreme shortage of organs transplant professionals continue to explore various strategies to expand the donor pool. Transplantation of kidneys from older and very young donors are two such options. Although kidneys from young donors (less than 5 years of age) have been associated with a high rate of technical complications and suboptimal results, use of these kidneys en bloc has been advocated to improve the outcomes. We reviewed our experience with en bloc kidney transplantation at the University of Kentucky over the past 10 years. Between 1991 and 2000 ten patients underwent k

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Pivtorak, Volodymyr, Volodymyr Monastyrskiy, Kateryna Pivtorak, and Mykola Bulko. "RISK OF OCCURRENCE AND WAYS TO IMPROVE THE TREATMENT OF UROLITHIASIS IN PATIENTS WITH A SINGLE KIDNEY." Wiadomości Lekarskie 75, no. 9 (2022): 2141–45. http://dx.doi.org/10.36740/wlek202209117.

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The aim: To summarize the state of the problem of urolithiasis in patients with a single kidney and consider current views on improving its treatment based on the analysis of world literature. Materials and methods: The study conducted a thorough analysis of modern scientific literature sources in the international scientometric database, which highlighted the development of urolithiasis in patients with a single kidney and the peculiarities of its treatment. The main ways to improve treatment are identified. A critical assessment of the achievements and shortcomings of various surgical treatm

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Parajuli, Sandesh, Jacqueline Garonzik-Wang, Brad C. Astor, et al. "Twelve Thousand Kidney Transplants Over More Than 55 Y: A Single-center Experience." Transplantation Direct 10, no. 2 (2024): e1575. http://dx.doi.org/10.1097/txd.0000000000001575.

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Background. Kidney transplant outcomes have dramatically improved since the first successful transplant in 1954. In its early years, kidney transplantation was viewed more skeptically. Today it is considered the treatment of choice among patients with end-stage kidney disease. Methods. Our program performed its first kidney transplant in 1966 and recently performed our 12 000th kidney transplant. Here, we review and describe our experience with these 12 000 transplants. Transplant recipients were analyzed by decade of date of transplant: 1966–1975, 1976–1985, 1986–1995, 1996–2005, 2006–2015, a

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Fontana, Céline, Matthias Diebold, Patrizia Amico, et al. "Bleeding risk after native and transplant kidney biopsy – a single-centre observational study." Swiss Medical Weekly 155, no. 6 (2025): 4409. https://doi.org/10.57187/s.4409.

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STUDY AIM: Renal biopsies provide important and decisive information for diagnosis and therapy. Although biopsies are considered safe, bleeding complications remain a concern. We analysed the complication rate after kidney biopsies in native and transplant kidneys and their association with platelet function analyser bleeding time (PFA BT) and estimated glomerular filtration rate (eGFR). METHODS: This single-centre observational study included all patients who underwent an ultrasound-guided kidney biopsy at the University Hospital Basel from 2015 to August 2019. The main objective was to inves

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Slagter, Julia S., Elsaline Rijkse, Roeland F. De Wilde, et al. "The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study." Journal of Clinical Medicine 12, no. 7 (2023): 2647. http://dx.doi.org/10.3390/jcm12072647.

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Background: Little is known about the influence of the duration of the kidney back-table preparation period and kidney temperature on graft outcomes after transplantation. The aim of this study is to investigate the back-table duration and its relation to graft outcome and the relation between kidney temperature and graft outcome. Methods: In this prospective cohort study, deceased donor kidney temperature is measured at fixed time points using an infrared thermometer during back-table preparation and transplantation. Additionally, the back-table duration is measured using a timer. Results: Be

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Baylis, Christine, and Curtis B. Wilson. "Sex and the Single Kidney." American Journal of Kidney Diseases 13, no. 4 (1989): 290–98. http://dx.doi.org/10.1016/s0272-6386(89)80035-6.

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Sarma, Debanga, Sarbartha Kumar Pratihar, Rajeev T. P., Sasanka K. Barua, Puskal K. Bagchi, and Mandeep Phukan. "Duplex kidney anomalies and associated pathology: a single centre retrospective review." International Surgery Journal 7, no. 1 (2019): 76. http://dx.doi.org/10.18203/2349-2902.isj20195619.

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Background: Duplex kidneys are common developmental renal anomaly with an incidence of 1% in healthy adult population.Adult individuals may present as non-functional moiety, calculus disease or an incidental finding. Duplex kidney is defined as a renal unit comprised of two pelvicalyceal systems. Based on the degree of fusion, it can present as bifid renal pelvis, partial ureteric duplication (Y-shaped ureter), incomplete ureteric duplication with ureters joining near or in bladder wall (V-shaped ureter) and complete ureteric duplication with separate ureteric orifices. The purpose of this stu

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Singh, Shanky. "Management of Lymphocele Formation Following Kidney Transplantation: A Single Centre Experience." Journal of Medical Science And clinical Research 05, no. 06 (2017): 23576–81. http://dx.doi.org/10.18535/jmscr/v5i6.127.

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Oruc, Aysegul, Alparslan Ersoy, Gulen Tandogan, Derya Karadayı, Abdulmecit Yildiz, and Cuma Bulent Gul. "Exclusion Reasons of Living Kidney Donor Candidates: A Single-Center Experience." Turkish Nephrology Dialysis Transplantation 23, no. 2 (2014): 112–17. http://dx.doi.org/10.5262/tndt.2014.1002.06.

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Okumura, Kenji, Suguru Ohira, Ryosuke Misawa, Seigo Nishida, Steven Lansman, and Abhay Dhand. "A Paired Kidney Analysis of Simultaneous Heart-Kidney Transplantation and Kidney Transplantation After Heart Transplantation." Annals of Surgery Open 6, no. 2 (2025): e582. https://doi.org/10.1097/as9.0000000000000582.

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Objective: To assess the outcomes of a pair of kidneys from a single donor used for simultaneous heart-kidney transplantation (SHKT) or kidney after heart transplantation (KAH). Background: An Increase in kidney dysfunction among heart transplant candidates has led to an increased need for SHKT and KAH. The risk of early kidney graft loss and mortality is higher in SHKT compared with kidney-alone recipients. Methods: Among adult kidney transplant recipients from Oct 2014 to Oct 2022, outcomes were compared between paired kidney-alone vs SHKT and kidney-alone vs KAH. Paired kidney models were u

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Wang, Xuexiang, Ashley C. Johnson, Jennifer M. Sasser, Jan M. Williams, Leah C. Solberg Woods, and Michael R. Garrett. "Spontaneous one-kidney rats are more susceptible to develop hypertension by DOCA-NaCl and subsequent kidney injury compared with uninephrectomized rats." American Journal of Physiology-Renal Physiology 310, no. 10 (2016): F1054—F1064. http://dx.doi.org/10.1152/ajprenal.00555.2015.

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There is little clinical data of how hypertension may influence individuals with nephron deficiency in the context of being born with a single kidney. We recently developed a new rat model (the heterogeneous stock-derived model of unilateral renal agenesis rat) that is born with a single kidney and exhibits progressive kidney injury and decline in kidney function with age. We hypothesized that DOCA-salt would induce a greater increase in blood pressure and therefore accelerate the progression of kidney injury in rats born with a solitary kidney compared with rats that have undergone unilateral

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Kumar, Uday, and Ratna Prabha. "Study of prehilar branching pattern of renal artery in human cadaveric kidneys." National Journal of Clinical Anatomy 05, no. 02 (2016): 086–90. http://dx.doi.org/10.1055/s-0039-3401599.

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Abstract Background and aims: Kidneys are the pair of excretory organs situated retroperitoneally in the lumbar region on either side of vertebral column. Classically there is a single renal artery supplying each kidney which arises from abdominal aorta. Understanding the anatomy of vascular pattern of kidney is important for clinicians to perform renal transplantation, interventional radiological stodies. The present stody was undertaken for studying the prehilar vascular pattern of renal artery. Material and methods: Kidneys were collected from the department of Anatomy, Navodaya Medical Col

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Nechiporenko, A. N., D. M. Vasilevich, G. V. Yutsevich, and N. A. Nechiporenko. "ACUTE PURULENT PYELONEPHRITIS OF THE SINGLE KIDNEY." Journal of the Grodno State Medical University 20, no. 3 (2022): 355–58. http://dx.doi.org/10.25298/2221-8785-2022-20-3-355-358.

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Background. One of the life-threatening diseases among patients with a single kidney is acute purulent pyelonephritis (APP). The disease is accompanied by oliguria or anuria and in many cases comes with the development of multiple organ dysfunction. Objectives. To present the features of the clinical manifestations of APP of a solitary kidney, the results of clinical and laboratory examination, the role of kidney imaging methods (USG, MRI and contrast-enhanced CT) in identifying foci of purulent destruction in the parenchyma, and the immediate results of treatment of patients with APP of a sol

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Gruessner, Rainer W. G., Arthur J. Matas, Goncal Lloveras, et al. "Pediatric donors – A risk factor in renal retransplantation." Clinical Transplantation 3, no. 6 (1989): 349–54. http://dx.doi.org/10.1111/j.1399-0012.1989.tb00567.x.

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Between January 1971 and February 1988, 1121 cadaver donor kidney transplants were performed at the University of Minnesota. Of these, 873 (77.9%) were from adult (> 15 years of age) donors, 117 (10.4%) from adolescents (> 10, < = 15) and 131 (11.7%) from pediatric (< = 10) donors. Of the last group, 25% of the patients received double and 75% single pediatric cadaver kidney transplants. We compared outcome of pediatric, adolescent and adult donor transplants. There was no difference in patient survival between recipient groups. One‐ and 5‐yr graft survival was 74% and 54% for reci

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Morozov, Darya, Neda Parvin, Mark Conaway, et al. "Estimating Nephron Number from Biopsies: Impact on Clinical Studies." Journal of the American Society of Nephrology 33, no. 1 (2021): 39–48. http://dx.doi.org/10.1681/asn.2021070998.

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BackgroundAccumulating evidence supports an association between nephron number and susceptibility to kidney disease. However, it is not yet possible to directly measure nephron number in a clinical setting. Recent clinical studies have used glomerular density from a single biopsy and whole kidney cortical volume from imaging to estimate nephron number and single nephron glomerular filtration rate. However, the accuracy of these estimates from individual subjects is unknown. Furthermore, it is not clear how sample size or biopsy location may influence these estimates. These questions are critic

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Lake, Blue B., Rajasree Menon, Seth Winfree, et al. "An atlas of healthy and injured cell states and niches in the human kidney." Nature 619, no. 7970 (2023): 585–94. http://dx.doi.org/10.1038/s41586-023-05769-3.

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AbstractUnderstanding kidney disease relies on defining the complexity of cell types and states, their associated molecular profiles and interactions within tissue neighbourhoods1. Here we applied multiple single-cell and single-nucleus assays (>400,000 nuclei or cells) and spatial imaging technologies to a broad spectrum of healthy reference kidneys (45 donors) and diseased kidneys (48 patients). This has provided a high-resolution cellular atlas of 51 main cell types, which include rare and previously undescribed cell populations. The multi-omic approach provides detailed transcriptomic p

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Terrell, Tom, Mike Woods, and David O. Hough. "Blunt Trauma Reveals a Single Kidney." Physician and Sportsmedicine 25, no. 11 (1997): 75–79. http://dx.doi.org/10.3810/psm.1997.11.1442.

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Calado, Adriano A., Antonio Macedo Jr., and Miguel Srougi. "Cake kidney drained by single ureter." International braz j urol 30, no. 4 (2004): 321–22. http://dx.doi.org/10.1590/s1677-55382004000400011.

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Noel, Sanjeev, Niraj M. Desai, Abdel Rahim A. Hamad, and Hamid Rabb. "Sex and the single transplanted kidney." Journal of Clinical Investigation 126, no. 5 (2016): 1643–45. http://dx.doi.org/10.1172/jci87428.

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Goussous, Naeem, Richard Perez, Lea Matsuoka, Sophoclis Alexopoulos, and Junichiro Sageshima. "Outcomes of Single Pediatric Kidney Grafts." American Journal of Transplantation 25, no. 1 (2025): S93. https://doi.org/10.1016/j.ajt.2024.12.178.

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Romero, R., J. Bonal, E. Campo, A. Pelegri, and A. Palacin. "Glomerulocystic Kidney Disease: A Single Entity?" Nephron 63, no. 1 (1993): 100–103. http://dx.doi.org/10.1159/000187150.

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Miller, Eric, C. Wilson, G. Sawczyn, et al. "SINGLE PORT ROBOT-ASSISTED KIDNEY TRANSPLANTATION." Transplantation 104, S3 (2020): S416. http://dx.doi.org/10.1097/01.tp.0000700724.62445.e1.

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Magerl, Kris, Matthias Diebold, Caroline Wehmeier, et al. "Outcome of kidney transplantation from senior deceased donors: a single centre study." Swiss Medical Weekly 153, no. 8 (2023): 40098. http://dx.doi.org/10.57187/smw.2023.40098.

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BACKGROUND: Addressing the current demographic development, the efficacy and safety of kidney transplantations from very senior donors needs to be carefully evaluated. The aim of this study was to analyse patient and graft outcomes of kidney allograft recipients stratified by donor age. METHODS: We retrospectively investigated n = 491 patients from a prospective, observational renal transplant cohort. Patients with kidneys from very old donors (n = 75, aged >70 years), elderly donors (n = 158, between 60–70 years), and regular donors (n = 258, aged <60 years) were investigated. The prima

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Wang, Lei, Ximing Wang, Shan Jiang, et al. "Graft function assessment in mouse models of single- and dual-kidney transplantation." American Journal of Physiology-Renal Physiology 315, no. 3 (2018): F628—F636. http://dx.doi.org/10.1152/ajprenal.00068.2018.

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Animal models of kidney transplantation (KTX) are widely used in studying immune response of hosts to implanted grafts. Additionally, KTX can be used in generating kidney-specific knockout animal models by transplantation of kidneys from donors with global knockout of a gene to wild-type recipients or vice versa. Dual-kidney transplantation (DKT) provides a more physiological environment for recipients than single-kidney transplantation (SKT). However, DKT in mice is rare due to technical challenges. In this study, we successfully performed DKT in mice and compared the hemodynamic response and

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Tripani, Wenni Juniarni, Muhammad In’am Ilmiawan, and Willy Handoko. "THE EFFECT OF SINGLE- AND REPEATED- EXCESSIVE SWIMMING EXERCISE ON KIDNEY HISTOPATHOLOGY OF MALE RATS WISTAR STRAIN (Rattus norvegicus)." Muhammadiyah Medical Journal 1, no. 1 (2020): 33. http://dx.doi.org/10.24853/mmj.1.1.33-42.

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Background: Physical exercise aims to improve or maintain physical fitness. However, excessive physical exercise may cause increase of oxidative stress which leads to cellular injury, including in the proximal tubules of kidney. This research aims to find out the effect of single- and repeated- excessive swimming exercise to the kidney histopathology of male wistar rats (Rattus norvegicus). Methods: This research was an experimental study with complete random and post test only control group design. Twenty seven male wistar rats were divided into three treatment groups: control group, single-

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Kim, Irene K., Jane C. Tan, Jessica Lapasia, Arvand Elihu, Stephan Busque, and Marc L. Melcher. "Incidental kidney stones: a single center experience with kidney donor selection." Clinical Transplantation 26, no. 4 (2011): 558–63. http://dx.doi.org/10.1111/j.1399-0012.2011.01567.x.

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Faenza, A., R. Bertelli, E. Capocasale, et al. "DOUBLE KIDNEY COMPARED TO SINGLE KIDNEY TRANSPLANTATION: A MULTICENTRIC ITALIAN STUDY." Transplantation 86, Supplement (2008): 606. http://dx.doi.org/10.1097/01.tp.0000331020.06664.45.

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Alves, Everton Fernando, Sueli Donizete Borelli, and Luiza Tamie Tsuneto. "Autosomal dominant polycystic kidney disease: possible influences of single nucleotide polymorphism in cytokine genes." Perspectivas Médicas 26, no. 1 (2015): 5–15. https://doi.org/10.6006/perspectmed.20150101.56372S1645.

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Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited diseases in adults and is caused by mutations in one of two genes, PKD1 or PKD2, which result in accumulation of cysts in the kidneys that can lead to a loss of function. Is the third leading cause of chronic kidney disease (CKD) stage 5. Inflammation has been considered one of the responsible for the progression of CKD. Cytokines act directly in this process by increasing or decreasing the inflammatory response. The stimulation of these cytokines is associated with variants in cytokine genes. These variants may

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Steele, Samantha EJ, Jayne E. Terry, Louise M. Page, and Joanna C. Girling. "Pregnancy in women known to be living with a single kidney." Obstetric Medicine 12, no. 1 (2018): 22–26. http://dx.doi.org/10.1177/1753495x18784081.

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There is a paucity of data on pregnancy outcome in women living with a single kidney from all causes. Current thinking is extrapolated from living kidney donors, a group biased by strict selection criteria. We present a cohort of 26 women with a solitary functioning kidney; 11 women had an acquired single kidney of whom only 1 was a living donor and 15 had a congenital single kidney. Median time living with a single kidney was 28 years. None booked with hypertension or proteinuria. Urinary tract infection complicated 50% of pregnancies. Worryingly, 35% developed pre-eclampsia, gestational prot

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Gyawali, Prem, Sujeet Poudyal, Suman Chapagain, Bhojraj Luitel, Pawan Chalise, and Uttam Sharma. "Upside-down kidney transplantation using single-suture single-knot technique." Indian Journal of Transplantation 13, no. 4 (2019): 264. http://dx.doi.org/10.4103/ijot.ijot_18_19.

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Koper, Lindsey, Rachell L. Quarles, Janine M. Ziermann-Canabarro, Tashanti Bridgett, Paola Correa-Alfonzo, and Sulman J. Rahmat. "Anatomical and Histological Analyses of Rare Pancake Kidney." Anatomia 3, no. 3 (2024): 202–14. http://dx.doi.org/10.3390/anatomia3030016.

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During anatomical dissection of a female body donor at the Howard University College of Medicine, a rare renal anomaly was discovered. Detailed anatomical and histological analyses on this anomaly were compared to a normal kidney from another donor and previously published reports from a comprehensive literature review. Anatomical assessment confirmed the condition of pancake kidney, a rare form of completely fused, ectopic kidneys without an isthmus. Due to the lack of symptoms in patients with this condition and the limited number of published case reports, very little information is availab

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Grabnar, Jera, and Rina Rus. "Renal injury in children with a congenital solitary kidney: A single center experience." Srpski arhiv za celokupno lekarstvo, no. 00 (2025): 25. https://doi.org/10.2298/sarh241114025g.

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Introduction /Objective. Reduced kidney length, low birth weight, obesity, and ipsilateral congenital anomalies of the kidney and urinary tract (CAKUT) are risk factors for renal injury (hypertension, proteinuria, and chronic kidney disease) in single-functioning kidneys. Our study aimed to investigate the risk factors for renal injury and outcome in children with congenital solitary kidney (CSK). Methods. We collected data from the medical records of 95 children with CSK. Results. Children with CSK were predominantly male (61%). An abnormal ultrasound (US) view of a solitary kidney was found

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McCracken, Emily KE, Colleen L. Jay, Matthew Garner, et al. "The Kidney Not Taken: Single Kidney Use in Deceased Donors." Journal of the American College of Surgeons, January 15, 2024. http://dx.doi.org/10.1097/xcs.0000000000000968.

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Background: The nonutilization rate for kidneys recovered from deceased donors is increasing, rising to 27% in 2023. In 10% of these cases, one kidney is transplanted but the mate kidney is not. Study Design: We conducted a retrospective, single-center cohort study from December 2001 to May 2023 comparing single kidneys transplanted at our center (where the contralateral kidney was not used) to kidneys where both were transplanted separately, at least one of which was at our center. Results: We performed 395 single deceased-donor kidney transplants in which the mate kidney was not transplanted

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Liao, Jinling, Zhenyuan Yu, Yang Chen, et al. "Single-cell RNA sequencing of human kidney." Scientific Data 7, no. 1 (2020). http://dx.doi.org/10.1038/s41597-019-0351-8.

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AbstractA comprehensive cellular anatomy of normal human kidney is crucial to address the cellular origins of renal disease and renal cancer. Some kidney diseases may be cell type-specific, especially renal tubular cells. To investigate the classification and transcriptomic information of the human kidney, we rapidly obtained a single-cell suspension of the kidney and conducted single-cell RNA sequencing (scRNA-seq). Here, we present the scRNA-seq data of 23,366 high-quality cells from the kidneys of three human donors. In this dataset, we show 10 clusters of normal human renal cells. Due to t

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Husain, S. Ali, Kristen L. King, Shelief Robbins-Juarez, Joel T. Adler, Kasi R. McCune, and Sumit Mohan. "Number of Donor Renal Arteries and Early Outcomes After Deceased Donor Kidney Transplantation." Kidney360, September 8, 2021, 10.34067/KID.0005152021. http://dx.doi.org/10.34067/kid.0005152021.

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Background: Anatomical abnormalities increase the risk of deceased donor kidney discard but their impact on transplant outcomes is understudied. We sought to determine the impact of multiple donor renal arteries on early outcomes after deceased donor kidney transplantation. Methods: For this retrospective cohort study, we identified 1443 kidneys from 832 deceased donors with ≥1 kidney transplanted at our center (2006-2016). We compared the odds of delayed graft function and 90-day graft failure using logistic regression. To reduce potential selection bias, we then repeated the analysis using a

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