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1

SHEN Hong-jun, 沈宏君, 张瑞 ZHANG Rui, and 卢辉东 LU Hui-dong. "Design of An Amorphous Silicon Thin-film Sloar Cell with Absorption Enhancement." Chinese Journal of Luminescence 34, no. 6 (2013): 753–57. http://dx.doi.org/10.3788/fgxb20133406.0753.

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2

Leibel, Steven A., Gerald J. Kutcher, Radhe Mohan, Louis B. Harrison, John G. Armstrong, Michael J. Zelefsky, Thomas J. LoSasso, et al. "Three-dimensional conformal radiation therapy at the Memorial Sloan-Kettering Cancer Center." Seminars in Radiation Oncology 2, no. 4 (October 1992): 274–89. http://dx.doi.org/10.1016/1053-4296(92)90025-g.

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3

Roelofs, G. H. A., P. J. Groot, D. Steeghs, and G. Nelemans. "SDSS J1240-01: A New AM CVn Candidate from the Sloan Digital Sky Survey." International Astronomical Union Colloquium 194 (July 2004): 254. http://dx.doi.org/10.1017/s0252921100152996.

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A better understanding of the AM CVn population is crucial to constrain their candidacy as SN Ia progenitors, to test binary evolution (in particular the common-envelope phase), and to predict their observable gravitational radiation signature. An AM CVn dedicated search in the Sloan Digital Sky Survey-DRl resulted in the discovery of SDSS J124058.03-015919.2, a new AM CVn candidate previously identified as a DB white dwarf in the 2dF quasar survey.
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La, Trang H., Paul A. Meyers, Leonard H. Wexler, Kaled M. Alektiar, John H. Healey, Michael P. Laquaglia, Patrick J. Boland, and Suzanne L. Wolden. "Radiation therapy for Ewing’s sarcoma: Results from Memorial Sloan-Kettering in the modern era." International Journal of Radiation Oncology*Biology*Physics 64, no. 2 (February 2006): 544–50. http://dx.doi.org/10.1016/j.ijrobp.2005.07.299.

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5

Nicholls, Ralph. "A practical guide to intensity-modulated radiation therapy Authors: Memorial Sloan-Kettering Cancer Center." Australasian Physics & Engineering Sciences in Medicine 26, no. 4 (December 2003): 200. http://dx.doi.org/10.1007/bf03179182.

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6

Lebenthal, Justin, Junting Zheng, Paul A. Glare, Eileen Mary O'Reilly, and Andrew S. Epstein. "Prognostic value of the Memorial Sloan Kettering (MSK) prognostic score (MPS) in pancreatic ductal adenocarcinoma (PDAC)." Journal of Clinical Oncology 37, no. 31_suppl (November 1, 2019): 133. http://dx.doi.org/10.1200/jco.2019.37.31_suppl.133.

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133 Background: The MPS, a composite of the Neutrophil-Lymphocyte Ratio (NLR) and albumin, is an alternative prognostic tool to the Glasgow Prognostic Score (C-reactive protein and albumin). A retrospective analysis (jco.2016.34.26_suppl.36) of patients with PDAC suggested that the MPS predicts survival. This did not control for clinically relevant factors such as performance status (PS), metastatic sites, or cancer therapies. More discriminating prognostic tools are needed. Methods: A retrospective chart review identified patients at MSK with pathology-confirmed stage IV PDAC diagnosed from 2
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Chu, Florence C. H. "A Personal Reflection on the History of Radiation Oncology at Memorial Sloan-Kettering Cancer Center." International Journal of Radiation Oncology*Biology*Physics 80, no. 3 (July 2011): 845–50. http://dx.doi.org/10.1016/j.ijrobp.2010.02.027.

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Gapany, M. "Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience." Yearbook of Otolaryngology-Head and Neck Surgery 2007 (January 2007): 276–77. http://dx.doi.org/10.1016/s1041-892x(07)70230-5.

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Chen, W. C. Y., M. J. Zelefsky, D. G. Pfister, S. L. Berry, D. H. Kraus, and S. L. Wolden. "Intensity modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience." Journal of Clinical Oncology 23, no. 16_suppl (June 2005): 5541. http://dx.doi.org/10.1200/jco.2005.23.16_suppl.5541.

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Wolden, Suzanne L., William C. Chen, David G. Pfister, Dennis H. Kraus, Sean L. Berry, and Michael J. Zelefsky. "Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience." International Journal of Radiation Oncology*Biology*Physics 64, no. 1 (January 2006): 57–62. http://dx.doi.org/10.1016/j.ijrobp.2005.03.057.

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11

Bian, Fuyan, Lisa J. Kewley, Brent Groves, and Michael A. Dopita. "What drives the redshift evolution of strong emission line ratios?" Monthly Notices of the Royal Astronomical Society 493, no. 1 (January 29, 2020): 580–85. http://dx.doi.org/10.1093/mnras/staa259.

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ABSTRACT We study the physical mechanisms that cause the offset between low-redshift and high-redshift galaxies on the [O iii] λ5007/H β versus [N ii] λ6584/H α ‘Baldwin, Phillips & Terlevich’ (BPT) diagram using a sample of local analogues of high-redshift galaxies. These high-redshift analogue galaxies are selected from the Sloan Digital Sky Survey. Located in the same region on the BPT diagram as the ultraviolet selected galaxies at z ∼ 2, these high-redshift analogue galaxies provide an ideal local benchmark to study the offset between the local and high-redshift galaxies on the BPT di
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Liu, Jinzhong, and Yu Zhang. "The gravitational wave signal from close galaxy pairs." Proceedings of the International Astronomical Union 10, S312 (August 2014): 296–97. http://dx.doi.org/10.1017/s1743921315008054.

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AbstractThe early phase of coalescence of supermassive black hole binaries (SMBHBs) from their host galaxies provides a guaranteed source of low-frequency gravitational wave (GW) radiation by pulsar timing observations. Nowadays, SMBHBs are ubiquitous in the nuclei of galaxies. A latest sample of close galaxy pairs has been released from the Sloan Digital Sky Survey (SDSS) Data. A binary population synthesis (BPS) approach has been applied to study the characteristics of clusters and galaxies. Here we report how BPS, using SDSS results, can be used to determine the GW radiation from SMBHBs. In
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Shah, Neil J., Nadia Bahadur, Lauren Esposito, Andrew Niederhausern, Chelsea Nichols, Anjali Pillai, Fenil Gandhi, et al. "A comprehensive Memorial Sloan Kettering Cancer Center real-world data model: Core clinical data elements." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e18755-e18755. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e18755.

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e18755 Background: The 2016 21st Century Cures Act supports the use of Real-World Data (RWD) for regulatory decision/approval. Due to technological advances, a vast amount of health-related data are now available, but most are not standardized nor readily useable for research. Also, currently available standardized RWD models are not applicable across cancer types or oncology specialties (surgery, medical oncology, radiation oncology, pathology, radiology, etc.). To address these deficiencies Memorial Sloan Kettering Cancer Center (MSKCC) built a comprehensive, pan-cancer, pan-specialty RWD mo
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Katsoulakis, Evangelia, Nadeem Riaz, Brett Cox, James Mechalakos, Joan Zatcky, Mark Bilsky, and Yoshiya Yamada. "Delivering a third course of radiation to spine metastases using image-guided, intensity-modulated radiation therapy." Journal of Neurosurgery: Spine 18, no. 1 (January 2013): 63–68. http://dx.doi.org/10.3171/2012.9.spine12433.

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Object The objective of this study was to investigate the feasibility and safety of delivering a third course of radiation to patients with multiply recurrent metastatic disease to the spine. Methods Between 2009 and 2011, 10 patients received a third course of radiation to spinal metastases at Memorial Sloan–Kettering Cancer Center using image-guided intensity-modulated radiation therapy (IMRT). Patient and tumor characteristics, dosimetry details, and outcomes were obtained using retrospective chart review. Spinal imaging was performed prior to treatment and at regular follow-up intervals. T
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Kollmeier, Marisa, Chu-Cheng Kan, Bernard Bochner, Guido Dalbagni, Dean F. Bajorin, and Michael J. Zelefsky. "External beam radiotherapy for small cell carcinoma of the urinary bladder: The Memorial Sloan-Kettering experience." Journal of Clinical Oncology 30, no. 5_suppl (February 10, 2012): 290. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.290.

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290 Background: To report our experience using definitive external beam radiotherapy for small cell carcinoma of the urinary bladder. Methods: We reviewed records of 17 patients (14 male, 3 female) with small cell carcinoma of the urinary bladder treated at our institution with external beam radiation therapy (median dose 64.8Gy) for small cell carcinoma of the bladder between January 1994 and June 2011. Median age was 69 years. Sixteen (94.1%) patients received neoadjuvant and/or concurrent platinum-based chemotherapy. All patients underwent pretreatment maximal transurethral resection (visib
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de Arruda, Fernando F., Dev R. Puri, Joanne Zhung, Ashwatha Narayana, Suzanne Wolden, Margie Hunt, Hilda Stambuk, et al. "Intensity-modulated radiation therapy for the treatment of oropharyngeal carcinoma: The Memorial Sloan-Kettering Cancer Center experience." International Journal of Radiation Oncology*Biology*Physics 64, no. 2 (February 2006): 363–73. http://dx.doi.org/10.1016/j.ijrobp.2005.03.006.

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17

Abrey, Lauren E., Leah Ben-Porat, Katherine S. Panageas, Joachim Yahalom, Brian Berkey, Walter Curran, Christopher Schultz, et al. "Primary Central Nervous System Lymphoma: The Memorial Sloan-Kettering Cancer Center Prognostic Model." Journal of Clinical Oncology 24, no. 36 (December 20, 2006): 5711–15. http://dx.doi.org/10.1200/jco.2006.08.2941.

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Purpose The purpose of this study was to analyze prognostic factors for patients with newly diagnosed primary CNS lymphoma (PCNSL) in order to establish a predictive model that could be applied to the care of patients and the design of prospective clinical trials. Patients and Methods Three hundred thirty-eight consecutive patients with newly diagnosed PCNSL seen at Memorial Sloan-Kettering Cancer Center (MSKCC; New York, NY) between 1983 and 2003 were analyzed. Standard univariate and multivariate analyses were performed. In addition, a formal cut point analysis was used to determine the most
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Noch, Evan K., Sameer F. Sait, Shama Farooq, Tanya M. Trippett, and Alexandra M. Miller. "A case series of extraneural metastatic glioblastoma at Memorial Sloan Kettering Cancer Center." Neuro-Oncology Practice 8, no. 3 (February 3, 2021): 325–36. http://dx.doi.org/10.1093/nop/npaa083.

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Abstract Background Extraneural metastasis of glioma is a rare event, often occurring in patients with advanced disease. Genomic alterations associated with extraneural glioma metastasis remain incompletely understood. Methods Ten patients at Memorial Sloan Kettering Cancer Center diagnosed with extraneural metastases of glioblastoma (9 patients) and gliosarcoma (1 patient) from 2003 to 2018 were included in our analysis. Patient characteristics, clinical course, and genomic alterations were evaluated. Results Patient age at diagnosis ranged from 14 to 73, with 7 men and 3 women in this group.
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Rosenzweig, Kenneth E., Sonal Sura, Andrew Jackson, and Ellen Yorke. "Involved-Field Radiation Therapy for Inoperable Non–Small-Cell Lung Cancer." Journal of Clinical Oncology 25, no. 35 (December 10, 2007): 5557–61. http://dx.doi.org/10.1200/jco.2007.13.2191.

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PurposeDose escalation has been shown to improve local control in non–small-cell lung cancer (NSCLC) treated with definitive radiation therapy, but with increased complications. We implemented the use of involved-field radiotherapy (IFRT) in an effort to reduce toxicity while treating the gross tumor to higher doses. This analysis reports failure rates in uninvolved nodal regions with the use of IFRT.Patients and MethodsA total of 524 patients with NSCLC treated with three-dimensional conformal radiotherapy at Memorial Sloan-Kettering Cancer Center between 1991 and 2005 were reviewed. Only lym
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Masoudi, Mozhgan, and Reza Saffari. "Study of a quadratic redshift-based correction in f(R) gravity with Baryonic matter." International Journal of Modern Physics D 24, no. 11 (September 6, 2015): 1550091. http://dx.doi.org/10.1142/s0218271815500911.

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This paper is considered as a second-order redshift-based corrections in derivative of modified gravitational action, f(R), to explain the late time acceleration which is appeared by Supernova Type Ia (SNeIa) without considering the dark components. Here, we obtained the cosmological dynamic parameters of universe for this redshift depended corrections. Next, we used the recent data of SNeIa Union2, shift parameter of the cosmic background radiation, Baryon acoustic oscillation from sloan digital sky survey (SDSS), and combined analysis of these observations to put constraints on the parameter
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Rengan, Ramesh, Philip Paty, W. Douglas Wong, Jose Guillem, Martin Weiser, Larissa Temple, Leonard Saltz, and Bruce D. Minsky. "Distal cT2N0 Rectal Cancer: Is There an Alternative to Abdominoperineal Resection?" Journal of Clinical Oncology 23, no. 22 (August 1, 2005): 4905–12. http://dx.doi.org/10.1200/jco.2005.10.041.

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Purpose Patients with cT2N0 distal rectal cancer do not require adjuvant therapy. However, when a patient refuses an abdominoperineal resection (APR), is there an alternative? The purpose of this trial is to determine whether preoperative external-beam radiation therapy can increase the rate of sphincter preservation for patients with distal cT2N0 adenocarcinoma of the rectum. Patients and Methods Between April 1988 and October 2003, 27 patients with distal rectal adenocarcinoma staged T2 by clinical and/or endorectal ultrasound who were judged by the operating surgeon to require an APR were t
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Wolden, Suzanne L., Ira J. Dunkel, Mark M. Souweidane, Laura Happersett, Yasmin Khakoo, Karen Schupak, David Lyden, and Steven A. Leibel. "Patterns of Failure Using a Conformal Radiation Therapy Tumor Bed Boost for Medulloblastoma." Journal of Clinical Oncology 21, no. 16 (August 15, 2003): 3079–83. http://dx.doi.org/10.1200/jco.2003.11.140.

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Purpose: To assess the patterns of failure for patients with medulloblastoma receiving a conformal tumor bed boost rather than a boost to the entire posterior fossa. Patients and Methods: From 1994 to 2002, 32 consecutive patients with newly diagnosed medulloblastoma treated at Memorial Sloan-Kettering Cancer Center (New York, NY) received a conformal boost to the tumor bed in conjunction with craniospinal radiation therapy. Twenty-eight patients also received chemotherapy. The median age was 9 years (range, 3 to 34 years), and the male to female ratio was 3:1. Twenty-seven patients had standa
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Serenelli, Aldo, René D. Rohrmann, and Masataka Fukugita. "Nature of blackbody stars." Astronomy & Astrophysics 623 (March 2019): A177. http://dx.doi.org/10.1051/0004-6361/201834032.

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A selection of 17 stars in the Sloan Digital Sky Survey, previously identified as DC-class white dwarfs (WDs), has been reported to show spectra very close to blackbody radiation in the wavelength range from ultraviolet to infrared. Because of the absence of lines and other details in their spectra, the surface gravity of these objects has previously been poorly constrained, and their effective temperatures have been determined by fits to the continuum spectrum using pure helium atmosphere models. We computed model atmospheres with pure helium and H/He mixtures and used Gaia DR2 parallaxes tha
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Yi, Min, Funda Meric-Bernstam, Henry M. Kuerer, Elizabeth A. Mittendorf, Isabelle Bedrosian, Anthony Lucci, Rosa F. Hwang, Jaime R. Crow, Sheng Luo, and Kelly K. Hunt. "Evaluation of a Breast Cancer Nomogram for Predicting Risk of Ipsilateral Breast Tumor Recurrences in Patients With Ductal Carcinoma in Situ After Local Excision." Journal of Clinical Oncology 30, no. 6 (February 20, 2012): 600–607. http://dx.doi.org/10.1200/jco.2011.36.4976.

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Purpose Prediction of patients at highest risk for ipsilateral breast tumor recurrence (IBTR) after local excision of ductal carcinoma in situ (DCIS) remains a clinical concern. The aim of our study was to evaluate a published nomogram from Memorial Sloan-Kettering Cancer Center to predict for risk of IBTR in patients with DCIS from our institution. Patients and Methods We retrospectively identified 794 patients with a diagnosis of DCIS who had undergone local excision from 1990 through 2007 at the MD Anderson Cancer Center (MDACC). Clinicopathologic factors and the performance of the Memorial
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Lim, S., N. Y. Lee, M. G. Fury, R. A. Ghossein, A. R. Shaha, S. L. Wolden, and D. G. Pfister. "Doxorubicin and concurrent radiotherapy for anaplastic thyroid cancer: We need to do better." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 16506. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.16506.

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16506 Background: Anaplastic thyroid cancer (ATC) is a rare, aggressive malignancy. The potential for pathologic misclassification complicates the interpretation of published data. One treatment option for locoregionally (LR) advanced disease is weekly low-dose doxorubicin (D) with concurrent radiation therapy (RT), based on reported 2-year local control rates of 68% (ATC)/77% (other TC histologic subtypes) (Cancer 1987;60:2372). We looked to evaluate our experience with this general approach, but in a larger series which included pathologic confirmation of all ATC cases. Methods: Patients (pt
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Wilcox, Jessica, William Newman, Anne Reiner, Samantha Brown, Robert Young, Justin Chen, Kathryn Beal, et al. "SURG-04. SALVAGE RESECTION OF RECURRENT PREVIOUSLY-IRRADIATED BRAIN METASTASES: CLINICAL AND RADIOGRAPHIC OUTCOMES." Neuro-Oncology 22, Supplement_2 (November 2020): ii203—ii204. http://dx.doi.org/10.1093/neuonc/noaa215.851.

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Abstract BACKGROUND The management of brain metastasis (BrM) recurrence after stereotactic body radiotherapy (SBRT) poses a clinical challenge. The efficacy of salvage resection is undefined, and the role of adjuvant resection cavity reirradiation is unclear given the compounded risk of radiation injury. METHODS Retrospective analysis of previously-irradiated BrM that underwent resection between March 2003 and February 2020 at Memorial Sloan Kettering Cancer Center was performed. Only cases with histopathologic evidence of viable malignancy were included, and specimens were classified by the g
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Wisłocka, A. M., A. B. Kovačević, and A. Balbi. "Comparative analysis of the influence of Sgr A* and nearby active galactic nuclei on the mass loss of known exoplanets." Astronomy & Astrophysics 624 (April 2019): A71. http://dx.doi.org/10.1051/0004-6361/201834655.

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Context. The detailed evolution of exoplanetary atmospheres has been the subject of decade-long studies. Only recently, investigations began on the possible atmospheric mass loss caused by the activity of galactic central engines. This question has so far been explored without using available exoplanet data. Aims. The goal of this paper is to improve our knowledge of the erosion of exoplanetary atmospheres through radiation from supermassive black holes (SMBHs) undergoing an active galactic nucleus (AGN) phase. Methods. To this end, we extended the well-known energy-limited mass-loss model to
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Rothrock, Robert J., Yi Li, Eric Lis, Stephanie Lobaugh, Zhigang Zhang, Patrick McCann, Patricia Mae G. Santos, et al. "Hypofractionated spinal stereotactic body radiation therapy for high-grade epidural disease." Journal of Neurosurgery: Spine 33, no. 5 (November 2020): 680–87. http://dx.doi.org/10.3171/2020.4.spine20118.

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OBJECTIVETo characterize the clinical outcomes when stereotactic body radiation therapy (SBRT) alone is used to treat high-grade epidural disease without prior surgical decompression, the authors conducted a retrospective cohort study of patients treated at the Memorial Sloan Kettering Cancer Center between 2014 and 2018. The authors report locoregional failure (LRF) for a cohort of 31 cases treated with hypofractionated SBRT alone for grade 2 epidural spinal cord compression (ESCC) with radioresistant primary cancer histology.METHODSHigh-grade epidural disease was defined as grade 2 ESCC, whi
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Habib, Larissa A., Jasmine H. Francis, Armida WM Fabius, Pierre Y. Gobin, Ira J. Dunkel, and David H. Abramson. "Second primary malignancies in retinoblastoma patients treated with intra-arterial chemotherapy: the first 10 years." British Journal of Ophthalmology 102, no. 2 (June 9, 2017): 272–75. http://dx.doi.org/10.1136/bjophthalmol-2017-310328.

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Background/AimsSurvivors of retinoblastoma carry a lifetime risk of secondary malignancies. It is well established that external beam radiation increases this risk; however, the risk with ophthalmic artery chemosurgery (OAC) remains unknown. We report on 10 years of experience with OAC and the rate of second primary malignancy (SPM) development.MethodsThis is a single-centre retrospective review approved by the Memorial Sloan Kettering Cancer Center Institutional Review Board of all patients who received OAC over a 10-year period, from May 2006 to November 2016. The second tumour incidence and
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Sura, Sonal, Vishal Gupta, Ellen Yorke, Andrew Jackson, Howard Amols, and Kenneth E. Rosenzweig. "Intensity-modulated radiation therapy (IMRT) for inoperable non-small cell lung cancer: The Memorial Sloan-Kettering Cancer Center (MSKCC) experience." Radiotherapy and Oncology 87, no. 1 (April 2008): 17–23. http://dx.doi.org/10.1016/j.radonc.2008.02.005.

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Kishtagari, Ashwin, Isaac Alexander Bowman, Martin S. Tallman, Dan Douer, Ellin Berman, Peter G. Maslak, Renier J. Brentjens, and Eytan M. Stein. "Chronic Myeloid Leukemia After Adjuvant Treatment For Breast Cancer: Is It Therapy Related?" Blood 122, no. 21 (November 15, 2013): 2740. http://dx.doi.org/10.1182/blood.v122.21.2740.2740.

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Abstract Chronic Myeloid Leukemia (CML) is a rare myeloid neoplasm with an age-adjusted incidence of 1.6 per 100,000 people in the United States (http://seer.cancer.gov/statfacts/html/cmyl.html). Despite the understanding of the pathogenesis of CML – the fusion of BCR-ABL leading to a constitutively activated tyrosine kinase – underlying events that lead to a 9;22 translocation are incompletely elucidated. Although CML was the most common leukemia seen among survivors of Hiroshima and Nagasaki, other causative factors are not well defined. There is a known association between exposure to radia
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Tiersten, A., and L. B. Saltz. "Influence of inflammatory bowel disease on the ability of patients to tolerate systemic fluorouracil-based chemotherapy." Journal of Clinical Oncology 14, no. 7 (July 1996): 2043–46. http://dx.doi.org/10.1200/jco.1996.14.7.2043.

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PURPOSE To evaluate the safety of administering fluorouracil (5FU)-based chemotherapy to cancer patients with inflammatory bowel disease (IBD). PATIENTS AND METHODS We retrospectively reviewed all patients entered into the Memorial Sloan-Kettering Cancer Center clinical data base from 1985 through 1995 who had a diagnosis of IBD, had a gastrointestinal malignancy, and were treated with systemic 5FU-based chemotherapy. A total of 19 patient charts were identified and reviewed. RESULTS Fifty-three percent of patients reviewed experienced severe (grade III/IV) diarrhea on treatment. Sixty percent
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Adel, N. G., A. Khan, and C. Lucarelli. "Use of palonosetron 0.25 mg IV daily and incidence of nausea and vomiting in patients undergoing bone marrow transplantation (BMT)." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 16510. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.16510.

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16510 Background: Preparative regimens for BMT are associated with a high incidence of nausea and vomiting, which can negatively affect quality of life. It is important to evaluate the incidence of nausea and vomiting and understand which antiemetic regimens are most effective in these patients in order to improve outcomes. Methods: A retrospective review of patients admitted to the adult BMT Unit at Memorial Sloan-Kettering Cancer Center (MSKCC) between 1/1/05 and 12/31/05 was performed. Currently at MSKCC, palonosetron (0.25 mg IV daily) is used as the main antiemetic agent during the prepar
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Keam, Jennifer, Mark H. Bilsky, Ilya Laufer, Weiji Shi, Zhigang Zhang, Moses Tam, Joan Zatcky, Dale M. Lovelock, and Yoshiya Yamada. "No association between excessive wound complications and preoperative high-dose, hypofractionated, image-guided radiation therapy for spine metastasis." Journal of Neurosurgery: Spine 20, no. 4 (April 2014): 411–20. http://dx.doi.org/10.3171/2013.12.spine12811.

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Object Radiation therapy is known to impair wound healing. Higher dose per fraction is believed to increase this risk. This study sought to quantify rates of wound complication in patients receiving preoperative conventionally fractionated radiotherapy (XRT) or high-dose hypofractionated image-guided radiation therapy (IGRT) for spinal metastasis, and to identify predictors of wound complication. Methods The records of 165 consecutive patients who underwent spine surgery for metastasis at Memorial Sloan–Kettering Cancer Center between 1999 and 2010, with a history of prior radiation therapy, w
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Kattan, Michael W., Michael J. Zelefsky, Patrick A. Kupelian, Peter T. Scardino, Zvi Fuks, and Steven A. Leibel. "Pretreatment Nomogram for Predicting the Outcome of Three-Dimensional Conformal Radiotherapy in Prostate Cancer." Journal of Clinical Oncology 18, no. 19 (October 19, 2000): 3352–59. http://dx.doi.org/10.1200/jco.2000.18.19.3352.

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PURPOSE: Several studies have defined risk groups for predicting the outcome after external-beam radiotherapy of localized prostate cancer. However, most models formed patient risk groups, and none of these models considers radiation dose as a predictor variable. The purpose of this study was to develop a nomogram to improve the accuracy of predicting outcome after three-dimensional conformal radiotherapy. MATERIALS AND METHODS: This study was a retrospective, nonrandomized analysis of patients treated at the Memorial Sloan-Kettering Cancer Center between 1988 and 1998. Clinical parameters of
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Kattan, Michael W., Michael J. Zelefsky, Patrick A. Kupelian, Daniel Cho, Peter T. Scardino, Zvi Fuks, and Steven A. Leibel. "Pretreatment Nomogram That Predicts 5-Year Probability of Metastasis Following Three-Dimensional Conformal Radiation Therapy for Localized Prostate Cancer." Journal of Clinical Oncology 21, no. 24 (December 15, 2003): 4568–71. http://dx.doi.org/10.1200/jco.2003.05.046.

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Purpose: There are several nomograms for the patient considering radiation therapy for clinically localized prostate cancer. Because of the questionable clinical implications of prostate-specific antigen (PSA) recurrence, its use as an end point has been criticized in several of these nomograms. The goal of this study was to create and to externally validate a nomogram for predicting the probability that a patient will develop metastasis within 5 years after three-dimensional conformal radiation therapy (CRT). Patients and Methods: We conducted a retrospective, nonrandomized analysis of 1,677
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Wilcox, Jessica, Samantha Brown, Anne Reiner, Robert Young, Justin Chen, Tejus Bale, Marc Rosenblum, et al. "MLTI-05. Adjuvant re-irradiation improves local control of surgically resected recurrent brain metastases." Neuro-Oncology Advances 3, Supplement_3 (August 1, 2021): iii13—iii14. http://dx.doi.org/10.1093/noajnl/vdab071.054.

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Abstract Background The efficacy of salvage resection (SR) of recurrent brain metastases (BrM) post-stereotactic radiosurgery (SRS) is not well described. We sought to characterize the impact of adjuvant post-salvage radiation therapy (PSRT) in this setting and identify tumor-specific variables that influence local control. Methods Retrospective analysis of post-SRS recurrent BrM that underwent SR between 2003–2020 at Memorial Sloan Kettering Cancer Center was performed. Cases with histologically-viable malignancy were included and stratified by receipt of adjuvant PSRT within 60 days of SR (P
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Setton, Jeremy, Nicola Caria, Jonathan Romanyshyn, Lawrence Koutcher, Suzanne L. Wolden, Michael J. Zelefsky, Nicholas Rowan, et al. "Intensity-Modulated Radiotherapy in the Treatment of Oropharyngeal Cancer: An Update of the Memorial Sloan-Kettering Cancer Center Experience." International Journal of Radiation Oncology*Biology*Physics 82, no. 1 (January 2012): 291–98. http://dx.doi.org/10.1016/j.ijrobp.2010.10.041.

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Gilbride, Lucas, Malika Siker, Joseph Bovi, Elizabeth Gore, Christopher Schultz, and William A. Hall. "Current Predictive Indices and Nomograms To Enable Personalization of Radiation Therapy for Patients With Secondary Malignant Neoplasms of the Central Nervous System: A Review." Neurosurgery 82, no. 5 (April 6, 2018): 595–603. http://dx.doi.org/10.1093/neuros/nyx631.

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Abstract The proper treatment of brain metastases continues to be a challenge for oncologists given the variability of individual patients’ prognoses and the variety of treatment options available to address brain metasteses. There have been efforts since the 1990s to develop prognostic indices and nomograms to help clinicians determine the best approach for individuals with secondary malignant neoplasms of the central nervous system. A literature search was performed to identify the existing prognostic tools published between January 1995 and January 2017. While there have been several report
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Kumar, Anita, Carla Casulo, Ranjana H. Advani, Elizabeth Budde, Paul M. Barr, Connie L. Batlevi, Philip Caron, et al. "Brentuximab Vedotin Combined With Chemotherapy in Patients With Newly Diagnosed Early-Stage, Unfavorable-Risk Hodgkin Lymphoma." Journal of Clinical Oncology 39, no. 20 (July 10, 2021): 2257–65. http://dx.doi.org/10.1200/jco.21.00108.

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PURPOSE To improve curability and limit long-term adverse effects for newly diagnosed early-stage (ES), unfavorable-risk Hodgkin lymphoma. METHODS In this multicenter study with four sequential cohorts, patients received four cycles of brentuximab vedotin (BV) and doxorubicin, vinblastine, and dacarbazine (AVD). If positron emission tomography (PET)-4–negative, patients received 30-Gy involved-site radiotherapy in cohort 1, 20-Gy involved-site radiotherapy in cohort 2, 30-Gy consolidation-volume radiotherapy in cohort 3, and no radiotherapy in cohort 4. Eligible patients had ES, unfavorable-ri
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Mandell, L., F. Ghavimi, T. Peretz, M. LaQuaglia, and P. Exelby. "Radiocurability of microscopic disease in childhood rhabdomyosarcoma with radiation doses less than 4,000 cGy." Journal of Clinical Oncology 8, no. 9 (September 1990): 1536–42. http://dx.doi.org/10.1200/jco.1990.8.9.1536.

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In an attempt to evaluate the radiocurability of microscopic disease in childhood rhabdomyosarcoma (RMS) with total tumor doses of less than 4,000 cGy, we performed a retrospective analysis of all patients with microscopic residual RMS who were treated at the Memorial Sloan-Kettering Cancer Center (MSKCC) during the years 1970 to 1987. There were 32 patients ranging in age from 3 months to 22 years (median, 6 years) with microscopic residual of either (1) a localized primary tumor (MSKCC, stage IB; Intergroup Rhabdomyosarcoma Study [IRS] group IIA), 19 patients; or (2) an involved lymph node r
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Zhan, Frank Qian, Vathani Sharon Packianathan, and Nathalie Charlotte Zeitouni. "Merkel Cell Carcinoma: A Review of Current Advances." Journal of the National Comprehensive Cancer Network 7, no. 3 (March 2009): 333–39. http://dx.doi.org/10.6004/jnccn.2009.0025.

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Merkel cell carcinoma (MCC) is a rare but aggressive cutaneous malignancy of neuroendocrine origin. Its incidence has tripled over the past 15 years. This article reviews the recent advancement in diagnosis, discoveries in pathogenesis, and updates in management. The acronym, AEIOU, has been proposed to aid in clinical identification. In addition to cytokeratin 20, newer immunohistochemical stains (in particular thyroid transcription factor-1 and neurofilament protein) have proven to be essential in pathologic diagnosis. Although immune suppression and ultraviolet radiation have long been asso
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Zinchenko, I. A., L. S. Pilyugin, F. Sakhibov, E. K. Grebel, A. Just, P. Berczik, Y. A. Nefedyev, J. M. Vílchez, and V. M. Shulga. "Peculiar motions of the gas at the centre of the barred galaxy UGC 4056." Astronomy & Astrophysics 628 (August 2019): A55. http://dx.doi.org/10.1051/0004-6361/201935897.

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We derive the circular velocity curves of the gaseous and stellar discs of UGC 4056, a giant barred galaxy with an active galactic nucleus (AGN). We analyse UGC 4056 using the 2D spectroscopy obtained within the framework of the Mapping Nearby Galaxies at APO (MaNGA) survey. Using images and the colour index g − r from the Sloan Digital Sky Survey (SDSS), we determined the tilt of the galaxy, which allows us to conclude that the galaxy rotates clockwise with trailing spiral arms. We found that the gas motion at the central part of the UGC 4056 shows peculiar features. The rotation velocity of
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Noy, Ariela, Joachim Yahalom, Leah Zaretsky, Ian Brett, and Andrew D. Zelenetz. "Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Detected by Clonotypic Polymerase Chain Reaction Despite Continuous Pathologic Remission Induced by Involved-Field Radiotherapy." Journal of Clinical Oncology 23, no. 16 (June 1, 2005): 3768–72. http://dx.doi.org/10.1200/jco.2005.10.018.

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Purpose Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is indolent and often associated with Helicobacter pylori bacterial infection. H pylori–independent MALT develops either in the absence of the bacteria or persists after bacterial eradication. We have previously demonstrated long-term pathologic remission after involved-field radiotherapy therapy (IFRT). We determined molecular remission status by clonotypic polymerase chain reaction (PCR). Patients and Methods Twenty-four consecutive patients with stage I to IIE gastric MALT lymphoma who obtained a pathologic remission after IF
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Morikawa, Aki, Adi Diab, Sujata Patil, Victoria Forte, Brian Blum, Robert J. Young, Kathryn Beal, Clifford Hudis, Andrew David Seidman, and Heather L. McArthur. "Radiation therapy for breast cancer (BC) with central nervous system (CNS) metastases: A contemporary experience at Memorial Sloan-Kettering Cancer Center (MSKCC)." Journal of Clinical Oncology 31, no. 26_suppl (September 10, 2013): 144. http://dx.doi.org/10.1200/jco.2013.31.26_suppl.144.

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144 Background: Many of the well-studied prognostic factors for patients with breast cancer (BC) brain metastases (BM) are based on data from an era when stereotactic radiosurgery (SRS) was not commonly used. In this study, we examined patient characteristics and outcomes for patients with CNS metastases who recently underwent cranial radiation at MSKCC. Methods: 173 consecutive BC patients with CNS metastases receiving SRS or WBRT from January 2009 to December 2011 were identified. Clinico-pathologic and treatment information was obtained by retrospective review. Patient characteristics and a
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Lee, K. S., R. M. Tuttle, R. A. Ghossein, S. G. Patel, A. R. Shaha, and N. Y. Lee. "Role of External Radiation Therapy in Patients With Advanced or Recurrent Non-Anaplastic Thyroid Cancer: The Memorial Sloan-Kettering Cancer Center Experience." International Journal of Radiation Oncology*Biology*Physics 69, no. 3 (November 2007): S454. http://dx.doi.org/10.1016/j.ijrobp.2007.07.1630.

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Edwards-Bennett, S. M., B. A. McCormick, L. M. Jacks, M. C. Azu, A. Y. Ho, S. N. Powell, and C. L. Brown. "Patterns of Utilization of Adjuvant Radiation Therapy and Outcomes in Black Women after Breast Conservation - The Memorial Sloan Kettering Cancer Center Experience." International Journal of Radiation Oncology*Biology*Physics 75, no. 3 (November 2009): S214. http://dx.doi.org/10.1016/j.ijrobp.2009.07.495.

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Terezakis, Stephanie A., Kyungmouk S. Lee, Ronald A. Ghossein, Michael Rivera, Robert M. Tuttle, Suzanne L. Wolden, Michael J. Zelefsky, et al. "Role of External Beam Radiotherapy in Patients With Advanced or Recurrent Nonanaplastic Thyroid Cancer: Memorial Sloan-Kettering Cancer Center Experience." International Journal of Radiation Oncology*Biology*Physics 73, no. 3 (March 2009): 795–801. http://dx.doi.org/10.1016/j.ijrobp.2008.05.012.

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Moskowitz, Craig H., Stephen D. Nimer, Andrew D. Zelenetz, Paul A. Hamlin, Steven M. Horwitz, Ariela Noy, Carol S. Portlock, et al. "Normalization of FDG-PET Pre-ASCT with Additional Non-Cross Resistant Chemotherapy Improves EFS in Patients with Relapsed and Primary Refractory Hodgkin Lymphoma-Memorial Sloan Kettering Protocol 04-047." Blood 112, no. 11 (November 16, 2008): 775. http://dx.doi.org/10.1182/blood.v112.11.775.775.

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Abstract We have reported that outcome of transplant-eligible patients (pts) with relapsed and primary refractory HL is determined by three pre-second-line chemotherapy (ST) risk factors (RF): remission duration of <1 yr., extranodal disease and B symptoms. In addition, normalization of FDG-PET prior to ASCT is the most important factor predicting favorable EFS. We now report the preliminary results of an ongoing phase II risk-adapted study where HL pts receive the following: Favorable risk (0–1 RF) - one cycle of standard dose ifosfamide, carboplatin and etoposide (ICE) ST followed by one
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Kelly, Brandon C., Marianne Vestergaard, Xiaohui Fan, Lars Hernquist, Philip Hopkins, and Aneta Siemiginowska. "The Distribution and Evolution of Black Hole Mass in Broad Line Quasars." Proceedings of the International Astronomical Union 5, S267 (August 2009): 263. http://dx.doi.org/10.1017/s174392131000640x.

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We present the first estimate of the black hole mass function (BHMF) of broad-line quasars (BLQSOs) that self-consistently corrects for incompleteness and the statistical uncertainty in the mass estimates, based on a sample of 9886 quasars at 1 < z < 4.5 drawn from the Sloan Digital Sky Survey. We find evidence for “cosmic downsizing” of black holes in BLQSOs, where the peak in their number density shifts to higher redshift with increasing black hole mass. We estimate the lifetime of the BLQSO phase to be 70 ± 5 Myr for supermassive black holes (SMBHs) at z = 1 with a mass of MBH = 109M⊙
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