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1

Chen, H., and M. A. Garrett. "Searching for Kardashev Type III civilisations from high q-value sources in the LoTSS-DR1 value-added catalogue." Monthly Notices of the Royal Astronomical Society 507, no. 3 (2021): 3761–70. http://dx.doi.org/10.1093/mnras/stab2207.

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ABSTRACT Kardashev Type III civilisations have by definition energy requirements that are likely to generate strong excess emission in the mid-infrared (MIR) that is associated with the waste heat they generate. For those civilisations that capture starlight via Dyson sphere like constructions, the Optical to MIR flux ratio of the host galaxies is also expected to be unusually low. Since a wide range of galaxy types adhere to the infrared-radio correlation (IRC), galaxies hosting Type III civilisations should also strongly deviate from this relation. Radio data can therefore play a crucial rol
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Martinez, Cristina A., Jordi Roca, Manuel Alvarez-Rodriguez, and Heriberto Rodriguez-Martinez. "miRNA-Profiling in Ejaculated and Epididymal Pig Spermatozoa and Their Relation to Fertility after Artificial Insemination." Biology 11, no. 2 (2022): 236. http://dx.doi.org/10.3390/biology11020236.

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MicroRNAs (miRNAs) are short non-coding RNAs (20–25 nucleotides in length) capable of regulating gene expression by binding -fully or partially- to the 3’-UTR of target messenger RNA (mRNA). To date, several studies have investigated the role of sperm miRNAs in spermatogenesis and their remaining presence toward fertilization and early embryo development. However, little is known about the miRNA cargo in the different sperm sources and their possible implications in boar fertility. Here, we characterized the differential abundance of miRNAs in spermatozoa from the terminal segment of the epidi
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Zhang, Hong-Ping, Bin Zhao, Rong-Ze Ma, Zhen-Rui Li, and Peng-Fei Wang. "Numerical simulation of coherent mid-infrared supercontinuum generation based on carbon chloride core tapered photonic crystal fibers." Laser Physics 33, no. 12 (2023): 125401. http://dx.doi.org/10.1088/1555-6611/ad04c4.

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Abstract We numerically studied coherent mid-infrared (MIR) supercontinuum (SC) generated by filling carbon chloride (CCl4, C2Cl4) into the tapered photonic crystal fiber (PCF). The mechanism involves nonlinear soliton compression, Raman soliton self-frequency shift and dispersive wave generated in a carbon chloride core tapered PCF pumped by a 1.98 μm femtosecond laser. Numerical solution of the generalized nonlinear Schrodinger equation shows that 1.15–5.5 μm (CCl4-core tapered PCF) and 1.15–5.7 μm (C2Cl4-core tapered PCF) coherent MIR-SC sources can be realized. Our results show that the ab
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Medina Villaamil, V., M. Blanco Calvo, S. M. Díaz Prado, et al. "MicroRNA for circulating tumor cells detection in breast cancer: In silico and in vitro analysis." Journal of Clinical Oncology 27, no. 15_suppl (2009): e22027-e22027. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e22027.

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e22027 Background: Detection of circulating tumor cells (CTC) may provide diagnostic and prognostic information in breast cancer (bc) patients. Deregulation of microRNAs (miRNAs) is frequent in tumors, including breast cancer. It is suggested miRNAs play a role in tumor progression. We hypothesized that miRNAs may constitute a promising new class of cancer biomarkers for CTC detection. Our objective has been to identify miRNAs potentially useful for CTC detection. Methods: Phase I preclinical study was performed by means of computational tools for miRNAs profiling including MIRGATOR, MIRBASE,
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Mustafin, R. N. "Relationship of MicroRNAs with Transposable Elements in the Type 1 Diabetes Development." Russian Archives of Internal Medicine 13, no. 6 (2024): 413–21. http://dx.doi.org/10.20514/2226-6704-2023-13-6-413-421.

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The review article describes the involvement of epigenetic factors in type 1 diabetes mellitus (T1DM) etiopathogenesis. The disease is characterized by changes in expression of microRNAs that affect the transcription of genes involved in autoimmune reactions, destruction of beta cells and insulin production. However, the cause of the observed epigenetic changes is still unclear. In evolution, the sources of microRNA genes are transposable elements, which occupy up to 45 % of the entire human DNA sequence and are drivers of epigenetic regulation in ontogenesis. They are sources of transcription
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Masterson, Megan, Kishalay De, Christos Panagiotou, et al. "JWST’s First View of Tidal Disruption Events: Compact, Accretion-driven Emission Lines and Strong Silicate Emission in an Infrared-selected Sample." Astrophysical Journal Letters 988, no. 2 (2025): L48. https://doi.org/10.3847/2041-8213/ade153.

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Abstract Mid-infrared (MIR) emission from tidal disruption events (TDEs) is a powerful probe of the circumnuclear environment around dormant supermassive black holes. This emission arises from the reprocessing of intrinsic emission into thermal MIR emission by circumnuclear dust. While the majority of optical- and X-ray-selected TDEs show only weak dust echoes consistent with primarily unobscured sight lines, there have been growing efforts aimed at finding TDEs in obscured environments using MIR selection methods. In this work, we present the first JWST observations of four MIR-selected TDEs
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Petroušková, Patrícia, Nikola Hudáková, Marcela Maloveská, Filip Humeník, and Dasa Cizkova. "Non-Exosomal and Exosome-Derived miRNAs as Promising Biomarkers in Canine Mammary Cancer." Life 12, no. 4 (2022): 524. http://dx.doi.org/10.3390/life12040524.

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Canine mammary cancer (CMC), similar to human breast cancer (HBC) in many aspects, is the most common neoplasm associated with significant mortality in female dogs. Due to the limited therapy options, biomarkers are highly desirable for early clinical diagnosis or cancer progression monitoring. Since the discovery of microRNAs (miRNAs or miRs) as post-transcriptional gene regulators, they have become attractive biomarkers in oncological research. Except for intracellular miRNAs and cell-free miRNAs, exosome-derived miRNAs (exomiRs) have drawn much attention in recent years as biomarkers for ca
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Metcalfe, Leo, B. Mcbreen, J. P. Kneib, and B. Altieri. "Gravitational Lensing and Deep Infrared Surveys." Symposium - International Astronomical Union 204 (2001): 217–32. http://dx.doi.org/10.1017/s0074180900226119.

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ISO's infrared camera was used to make deep mid-infrared (MIR) images through three gravitationally lensing clusters of galaxies. Observations were made at 7 μm and 15 μm covering more than 50 square arcminutes, with the lensing increasing the sensitivity to background sources significantly.A large number of MIR sources were detected behind the lenses and provide source counts, corrected for cluster contamination and lensing distortion effects, which exceed by a factor of 10 the expectation from local counts assuming a no-evolution model. The results are consistent with larger-area surveys and
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Pikir, Budi Susetio, Andrianto Andrianto, I. Gde Rurus Suryawan, Hanestya Oky Hermawan, Dian Paramita Kartikasari, and Primasitha Maharany Harsoyo. "microRNA-1 Induces Transdifferentiation of Peripheral Blood CD34+ Cells into Cardiomyocytes-like Cells." Indonesian Biomedical Journal 14, no. 3 (2022): 269–75. http://dx.doi.org/10.18585/inabj.v14i3.1888.

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BACKGROUND: Transdifferentiation is a method to provide cells sources for cellular cardiomyoplasty. CD34+ cells are potential cells sources because these cells can differentiate into cardiomyocytes through several mechanisms. MicroRNA (miR-1) is known to have the ability to inhibit the expression of histone deacetylase 4 (HDAC4). HDAC4 is a gene that essentially contributes in cardiomyocytes differentiation. However, the study reporting an evidence that miR-1 can induce transdifferentiation of CD34+ peripheral blood cells into mature cardiomyocytes is limited.METHODS: CD34+ cells were taken fr
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Lewellis, Stephen W., Danielle Nagelberg, Abhi Subedi, et al. "Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay." Journal of Cell Biology 200, no. 3 (2013): 337–55. http://dx.doi.org/10.1083/jcb.201207099.

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During animal development, SDF1 simultaneously guides various cell types to different targets. As many targets are in close proximity to one another, it is unclear how the system avoids mistargeting. Zebrafish trigeminal sensory neurons express the SDF1 receptor Cxcr4b and encounter multiple SDF1 sources during migration, but ignore all but the correct one. We show that miR-430 and Cxcr7b regulation of SDF1a are required for precise guidance. In the absence of miR-430 or Cxcr7b, neurons responded to ectopic SDF1a sources along their route and did not reach their target. This was due to a failu
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11

Eckart, A., J. Moultaka, T. Viehmann, et al. "New MIR Excess Sources north of the IRS 13 Complex." Astronomische Nachrichten 324, S1 (2003): 521–26. http://dx.doi.org/10.1002/asna.200385059.

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12

Harish, Santosh, Sangeeta Malhotra, James E. Rhoads, Tianxing Jiang, Huan Yang, and Kendrick Knorr. "Evidence for Black Holes in Green Peas from WISE Colors and Variability." Astrophysical Journal 945, no. 2 (2023): 157. http://dx.doi.org/10.3847/1538-4357/acb99c.

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Abstract We explore the presence of active galactic nuclei (AGNs)/black holes in Green Pea galaxies (GPs), motivated by the presence of high-ionization emission lines such as He ii and [Ne iii] in their optical spectra. In order to identify AGN candidates, we used mid-infrared (MIR) photometric observations from the all-sky Wide-field Infrared Survey Explorer (WISE) mission for a sample of 1004 GPs. Considering only >5σ detections with no contamination from neighboring sources in AllWISE, we select 31 GPs out of 134 as candidate AGNs based on a stringent three-band WISE color diagnostic. Us
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Roubelakis, Maria, Dimitra Zagoura, Ourania Trohatou, et al. "Identification and Functional Analysis of Novel miRNA Target Genes That Control Mesenchymal Stem Cell Function." Blood 112, no. 11 (2008): 2424. http://dx.doi.org/10.1182/blood.v112.11.2424.2424.

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Abstract Human mesenchymal stem cells (hMSCs) constitute a population of multipotent stem cells, easily expanded in culture and able to differentiate into many lineages. These features render MSCs a very attractive tool for developing new strategies for clinical applications based on cell therapy. So far, the most common sources of MSCs have been the bone marrow (BM) and the umbilical cord blood (UCB). Our group has recently isolated MSCs from a novel source, such as the amniotic fluid (AF) and characterized them based on their phenotype, pluripotency, proliferation rate, differentiation poten
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14

Melnik, Bodo C., Swen Malte John, Pedro Carrera-Bastos, and Gerd Schmitz. "MicroRNA-21-Enriched Exosomes as Epigenetic Regulators in Melanomagenesis and Melanoma Progression: The Impact of Western Lifestyle Factors." Cancers 12, no. 8 (2020): 2111. http://dx.doi.org/10.3390/cancers12082111.

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DNA mutation-induced activation of RAS-BRAF-MEK-ERK signaling associated with intermittent or chronic ultraviolet (UV) irradiation cannot exclusively explain the excessive increase of malignant melanoma (MM) incidence since the 1950s. Malignant conversion of a melanocyte to an MM cell and metastatic MM is associated with a steady increase in microRNA-21 (miR-21). At the epigenetic level, miR-21 inhibits key tumor suppressors of the RAS-BRAF signaling pathway enhancing proliferation and MM progression. Increased MM cell levels of miR-21 either result from endogenous upregulation of melanocytic
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15

Yong-hao, You, Wang Xian-guo, Xu Ming, and Zhao Jin-ping. "Expression and clinical significance of miR-139-5p in non-small cell lung cancer." Journal of International Medical Research 47, no. 2 (2019): 867–74. http://dx.doi.org/10.1177/0300060518815379.

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Objective MiR-139-5p is a common tumor-associated microRNA (miRNA), which inhibits the occurrence and development of malignant tumors from various tissue sources. We detected miR-139-5p expression levels in tissues from patients with non-small cell lung cancer (NSCLC) to explore the relationship between miR-139-5p expression and clinicopathological parameters. Methods MiR-139-5p expression levels were detected in cancerous and normal tissues from 60 NSCLC patients by fluorescence quantitative polymerase chain reaction, using normal paracancerous tissue as a control. The relationships between m
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16

Ronsini, Carlo, Pietro Fumiento, Irene Iavarone, Pier Francesco Greco, Luigi Cobellis, and Pasquale De Franciscis. "Liquid Biopsy in Endometriosis: A Systematic Review." International Journal of Molecular Sciences 24, no. 7 (2023): 6116. http://dx.doi.org/10.3390/ijms24076116.

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Despite laparoscopy being a standardized option to diagnose pelvic endometriotic implants, non-invasive biomarkers are necessary to avoid the discomfort of invasive procedures. Recent evidence suggests a potential role of microRNAs (miRNAs) as feasible biomarkers for the early diagnosis of endometriosis. Following the recommendations in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, we systematically searched PubMed, EMBASE, Scopus, Cochrane Library, and Science Direct in January 2023. We provided no restriction on the country and year of publication
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17

Masoura, V. A., I. Georgantopoulos, G. Mountrichas, et al. "The XXL Survey." Astronomy & Astrophysics 638 (June 2020): A45. http://dx.doi.org/10.1051/0004-6361/201937161.

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The combination of optical and mid-infrared (MIR) photometry has been extensively used to select red active galactic nuclei (AGNs). Our aim is to explore the obscuration properties of these red AGNs with both X-ray spectroscopy and spectral energy distributions (SEDs). In this study, we re-visit the relation between optical/MIR extinction and X-ray absorption. We use IR selection criteria, specifically the W1 and W2 WISE bands, to identify 4798 AGNs in the XMM-XXL area (∼25 deg2). Application of optical/MIR colours (r−W2 > 6) reveals 561 red AGNs (14%). Of these, 47 have available X-ray spe
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18

Seddon, Angela B., Bruce Napier, Ian Lindsay, et al. "Prospective on using fibre mid-infrared supercontinuum laser sources for in vivo spectral discrimination of disease." Analyst 143, no. 24 (2018): 5874–87. http://dx.doi.org/10.1039/c8an01396a.

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19

Bonnu, Christin H., Tiara Ayu Nugraha Putri, and Ernes Josias Blegur. "IN SILICO IDENTIFICATION OF PUTATIVE miRNAs TARGETING GME TO INCREASE ASCORBIC ACID IN TOMATO." Biospecies 18, no. 2 (2025): 1–10. https://doi.org/10.22437/biospecies.v18i2.44411.

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The primary natural sources of ascorbic acid or vitamin C are fruits and vegetables, withtomatoes being one of the most readily available and accessible examples. The biosynthesisof ascorbic acid through the L-galactose pathway plays a key role in regulating vitamin C production in tomatoes. microRNAs (miRNAs) are among the various regulators that interact with mRNA involved in this process. Investigating how miRNA regulates mRNA could provide crucial information for developing genetic engineering techniques to boost vitamin C production. The main purpose of this research is to identify potent
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Zhang, Tao, Chunfang Lv, Liling Li, et al. "Plasma miR-126 Is a Potential Biomarker for Early Prediction of Type 2 Diabetes Mellitus in Susceptible Individuals." BioMed Research International 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/761617.

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Type 2 diabetes mellitus (T2DM) is a major public health problem in China. Diagnostic markers are urgently needed to identify individuals at risk of developing T2DM and encourage them to adapt to a healthier life style. Circulating miRNAs present important sources of noninvasive biomarkers of various diseases. Recently, a novel plasma microRNA signature was identified in T2DM. Here, we evaluated the T2DM-related miRNA signature in plasma of three study groups: normal (fasting glucose (FG), 4.8–5.2 mmol/L), T2DM-susceptible (FG, 6.1–6.9 mmol/L), and T2DM individuals (FG, ≥7.0 mmol/L) and tested
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Wu, Tianqi, Hongming Song, Dan Xie, et al. "Mir-30b-5p Promotes Proliferation, Migration, and Invasion of Breast Cancer Cells via Targeting ASPP2." BioMed Research International 2020 (April 30, 2020): 1–12. http://dx.doi.org/10.1155/2020/7907269.

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Triple-negative breast cancer (TNBC) is the most aggressive subtypes of breast cancer, which has few effective targeted therapies. Various sources of evidence confirm that microRNAs (miRNAs) contribute to the progression and metastasis of human breast cancer. However, the molecular mechanisms underlying the changes in miRNAs expression and the regulation of miRNAs functions have not been well clarified. In this study, we found that the expression of miR-30b-5p was upregulated in breast cancer tissues and breast cancer cell lines, compared to paracancer tissues and normal breast cell lines. Mor
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Ishida, Tomoaki, Tomoe Ueyama, Dai Ihara, et al. "c-Myc/microRNA-17-92 Axis Phase-Dependently Regulates PTEN and p21 Expression via ceRNA during Reprogramming to Mouse Pluripotent Stem Cells." Biomedicines 11, no. 6 (2023): 1737. http://dx.doi.org/10.3390/biomedicines11061737.

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Induced pluripotent stem cells (iPSCs) are promising cell sources for regenerative medicine and disease modeling. iPSCs are commonly established by introducing the defined reprogramming factors Oct4, Sox2, Klf4, and c-Myc. However, iPSC reprogramming efficiency remains low. Although recent studies have identified microRNAs that contribute to efficient reprogramming, the underlying molecular mechanisms are not completely understood. miR-17-92 is highly expressed in embryonic stem cells and may play an important role in regulating stem cell properties. Therefore, we examined the role of miR-17-9
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23

Sojka, Lukasz, Zhuoqi Tang, Dinuka Jayasuriya, et al. "Milliwatt-Level Spontaneous Emission Across the 3.5–8 µm Spectral Region from Pr3+ Doped Selenide Chalcogenide Fiber Pumped with a Laser Diode." Applied Sciences 10, no. 2 (2020): 539. http://dx.doi.org/10.3390/app10020539.

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A spontaneous emission fiber source operating in the mid-infrared (MIR) wavelength range from 3.5 to 8 µm is demonstrated for the first time at output power levels of at least 1 mW. The source is a Pr3+-doped selenide chalcogenide, multimode, glass fiber pumped with commercially available laser diodes operating at 1.470 µm, 1.511 µm and 1.690 µm. This MIR spontaneous emission fiber source offers a viable alternative to broadband mid-infrared supercontinuum fiber sources, which are comparatively complex and costly. The MIR emission wavelength range is significant for molecular sensing applicati
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Feruza, Kh. Bobojonova. "A LOOK AT THE HISTORY OF MIR-ARAB MADRASA IN BUKHARA." LOOK TO THE PAST 5, Special issue 1 (2022): 94–102. https://doi.org/10.5281/zenodo.6758227.

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This article discusses the Mir Arab Madrassah, the most famous and prestigious madrassah of the Bukhara Emirate, its architectural structure, calligraphers, construction legends, the financial situation of students, supplies, the number of students, salaries and benefits, audiences, classes, sciences, the examination process, the Emir of Bukhara , who taught, and the educational process in the Mir Arab Madrasah today are covered in detail based on sources. In addition, the financial expenses of the Mir Arab madrasah are covered by additional funds allocated from the income of the fund, the waq
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Jiang, Rulan, and Bo Lönnerdal. "Milk-Derived miR-22–3p Promotes Proliferation of Human Intestinal Epithelial Cells (HIECs) by Regulating Gene Expression." Current Developments in Nutrition 6, Supplement_1 (2022): 294. http://dx.doi.org/10.1093/cdn/nzac053.035.

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Abstract Objectives MicroRNAs (miRNAs) are small non-coding RNA involved in RNA silencing and post-transcriptional regulation of gene expression. Milk exosomes are microvesicles containing miRNAs, and miR-22–3p (miR-22) abundantly appears in human milk exosomes. Both human milk exosomes and miR-22 survive in vitro gastrointestinal digestion. The aim of the current study was to evaluate effects of milk derived miR-22 on intestinal epithelial cells in early life. Methods To evaluate effects of miR-22 on intestinal epithelial cells and mimic uptake of miR-22 in exosomes by intestinal epithelial c
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Gaumnitz, Thomas, Arohi Jain, Martin Huppert, Inga Jordan, Fernando Ardana-Lamas, and Hans Jakob Wörner. "Complete characterisation of attosecond SXR pulses generated by MIR laser sources." EPJ Web of Conferences 205 (2019): 01021. http://dx.doi.org/10.1051/epjconf/201920501021.

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Attosecond streaking with broadband SXR continua leads to contributions from multiple overlapping lines in the photoelectron spectrum. The Volkov-transform generalized projection algorithm (VTGPA) is generalised to include all contributing photoelectron bands (multi-line VTGPA) for the reconstruction of ultra-broadband SXR continua. We further investigate the influence of the collection angle of photoelectron detectors on attosecond streaking spectrograms and show full reconstruction for angle-integrated streaking traces. Also, the effects of the photoionization dipole matrix elements on the r
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Ruiz, A., A. Corral, G. Mountrichas, and I. Georgantopoulos. "XMMPZCAT: A catalogue of photometric redshifts for X-ray sources." Astronomy & Astrophysics 618 (October 2018): A52. http://dx.doi.org/10.1051/0004-6361/201833117.

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Aims. The third version of the XMM-Newton serendipitous catalogue (3XMM), containing almost half million sources, is now the largest X-ray catalogue. However, its full scientific potential remains untapped due to the lack of distance information (i.e. redshifts) for the majority of its sources. Here we present XMMPZCAT, a catalogue of photometric redshifts (photo-z) for 3XMM sources. Methods. We searched for optical counterparts of 3XMM-DR6 sources outside the Galactic plane in the SDSS and Pan-STARRS surveys, with the addition of near-(NIR) and mid-infrared (MIR) data whenever possible (2MASS
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Sadri, Mahrou, Jiang Shu, Stephen D. Kachman, Juan Cui, and Janos Zempleni. "Milk exosomes and miRNA cross the placenta and promote embryo survival in mice." Reproduction 160, no. 4 (2020): 501–9. http://dx.doi.org/10.1530/rep-19-0521.

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Exosomes facilitate cell-to-cell communication by transferring regulatory molecules such as miRNA from donor to recipient cells, for example, miR-21-5p and miR-30d promote placentation. Exosomes and their miRNA cargos are not exclusively obtained from endogenous synthesis but may also be absorbed from dietary sources, such as milk. This study assessed the effects of milk exosomes and miRNA cargos on embryo development and fertility in C57BL/6 mice. Fluorophore-labeled milk exosomes, miR-21-5p and miR-30d accumulated in murine placenta and embryos following oral gavage. Seventeen mRNAs, miR-21-
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Hu, Zhipeng, and Lisheng Mao. "Mid-infrared Ensemble Variability of Broad-line and Narrow-line Seyfert 1 Galaxies." Astrophysical Journal 985, no. 1 (2025): 70. https://doi.org/10.3847/1538-4357/adcabb.

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Abstract We utilized multiepoch archival data from the Wide-field Infrared Survey Explorer to compare the variability at 3.4 μm (W1 band) and 4.6 μm (W2 band) of broad-line Seyfert 1 (BLSy1) galaxies and narrow-line Seyfert 1 (NLSy1) galaxies by employing the ensemble structure function (SF). Additionally, we investigated the dependence of mid-infrared (MIR) ensemble SF on common active galactic nucleus parameters. The main results are as follows. (1) The ensemble SF of BLSy1 galaxies is larger than that of NLSy1 galaxies at long rest-frame time lags. (2) The ensemble SFs of BLSy1 galaxies, NL
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Yazdani, Amir, Nikunj Dudani, Satoshi Takahama, et al. "Characterization of primary and aged wood burning and coal combustion organic aerosols in an environmental chamber and its implications for atmospheric aerosols." Atmospheric Chemistry and Physics 21, no. 13 (2021): 10273–93. http://dx.doi.org/10.5194/acp-21-10273-2021.

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Abstract. Particulate matter (PM) affects visibility, climate, and public health. Organic matter (OM), a uniquely complex portion of PM, can make up more than half of total atmospheric fine PM mass. We investigated the effect of aging on secondary organic aerosol (SOA) concentration and composition for wood burning (WB) and coal combustion (CC) emissions, two major atmospheric OM sources, using mid-infrared (MIR) spectroscopy and aerosol mass spectrometry (AMS). For this purpose, primary emissions were injected into an environmental chamber and aged using hydroxyl (diurnal aging) and nitrate (
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Corbelli, Edvige, Jonathan Braine, and Carlo Giovanardi. "Rise and fall of molecular clouds across the M 33 disk." Astronomy & Astrophysics 622 (February 2019): A171. http://dx.doi.org/10.1051/0004-6361/201834437.

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We carried out deep searches for CO line emission in the outer disk of M 33, at R > 7 kpc, and examined the dynamical conditions that can explain variations in the mass distribution of the molecular cloud throughout the disk of M 33. We used the IRAM-30 m telescope to search for CO lines in the outer disk toward 12 faint mid-infrared (MIR) selected sources and in an area of the southern outer disk hosting MA1, a bright HII region. We detect narrow CO lines at the location of two MIR sources at galactocentric distances of about 8 kpc that are associated with low-mass young stellar clusters,
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Pohl, Tobias, Peter Meindl, Uwe Johannsen, Dieter Taubert, and Lutz Werner. "Measurement of the absolute spectral responsivity in the mid-infrared based on the cryogenic electrical substitution radiometer and an optimized thermopile detector." Journal of Sensors and Sensor Systems 8, no. 1 (2019): 195–205. http://dx.doi.org/10.5194/jsss-8-195-2019.

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Abstract. The Physikalisch-Technische Bundesanstalt (PTB) expanded its capabilities of the absolute measurement of radiant power to the spectral range of the mid-infrared (MIR) by implementing additional MIR laser radiation sources at one of the PTB's cryogenic electrical substitution radiometer facilities. This extension enables absolute calibrations of the spectral responsivity of detectors in the MIR traceable to the International System of Units (SI). The thermopile detector TS-76 was characterized and calibrated in view of its spectral responsivity s(λ) in the wavelength range between 1.5
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Shen, Fengjiao, Xueyou Hu, Jun Lu, et al. "Performance Characterization of a Fully Transportable Mid-Infrared Laser Heterodyne Radiometer (LHR)." Sensors 23, no. 2 (2023): 978. http://dx.doi.org/10.3390/s23020978.

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A fully transportable laser heterodyne radiometer (LHR), involving a flexible polycrystalline mid-infrared (PIR) fiber-coupling system and operating around 8 µm, was characterized and optimized with the help of a calibrated high temperature blackbody source to simulate solar radiation. Compared to a mid-IR free-space sunlight coupling system, usually used in a current LHR, such a fiber-coupling system configuration makes the mid-infrared (MIR) LHR fully transportable. The noise sources, heterodyne signal, and SNR of the MIR LHR were analyzed, and the optimum operating local oscillator (LO) pho
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Manenti, Isabella, Irene Viola, Ugo Ala, et al. "Adaptation Response in Sheep: Ewes in Different Cortisol Clusters Reveal Changes in the Expression of Salivary miRNAs." Animals 13, no. 20 (2023): 3273. http://dx.doi.org/10.3390/ani13203273.

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Farm procedures have an impact on animal welfare by activating the hypothalamic-pituitary-adrenal axis that induces a wide array of physiological responses. This adaptive system guarantees that the animal copes with environmental variations and it induces metabolic and molecular changes that can be quantified. MicroRNAs (miRNAs) play a key role in the regulation of homeostasis and emerging evidence has identified circulating miRNAs as promising biomarkers of stress-related disorders in animals. Based on a clustering analysis of salivary cortisol trends and levels, 20 ewes were classified into
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Wasiah, Nadiyatur Rahmatikal, and Driejana Driejana. "KINETICS OF FORMALDEHYDE (HCHO) AND OZO (O3) IN URBAN AREA." JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG 12, no. 1 (2020): 212–23. https://doi.org/10.34011/juriskesbdg.v12i1.1794.

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Formaldehyde (HCHO) is a toxic compound and plays an important role in atmospheric chemical reactions as a source of radicals and precursor of oxidants (mainly ozone). HCHO generates from primary sources (motor vehicles) and secondary sources (photochemical reactions). However, carbonyl compounds monitoring and research on their roles in chemical reaction (ozone production) in Indonesia is still limited. This research investigated the contribution and relationship of hydrocarbons (formaldehyde) and ozone in urban areas. Formaldehyde measurements were carried out for two weeks using absorption
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Wang, Li, Shao-Yan Chang, and Ting Zhang. "MiR-324–5p Regulation in Disturbed Embryogenesis Induced by Folate Deficiency." Current Developments in Nutrition 4, Supplement_2 (2020): 1279. http://dx.doi.org/10.1093/cdn/nzaa058_037.

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Abstract Objectives Folate plays key role during embryogenesis. It is proved that folate deficiency is a risk factor for birth defects mainly exerting its effects through DNA methylation. Here, we want to discover the epigenetic process of DNA methylation in the regulation of miRNAs and thereby regulates neural tube closure through actions on target genes. Methods 40 fetuses with spina bifida and 46 control fetuses from Shanxi Province in China were enrolled to study miR-324–5p alternations with folate deficiency. Meanwhile, mice model with folate deficiency diet were built to study the effect
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Skorokhodov, Maxim V. "On the Issue of Printed Sources of the 6th Part of K.G. Paustovsky’s The Story of a Life “On Low Heat. (Book of Wanderings)”." Literary Fact 3, no. 33 (2024): 261–89. http://dx.doi.org/10.22455/2541-8297-2024-33-261-289.

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The article reveals the main milestones of Konstantin G. Paustovsky’s creative cooperation with the editors of the journals “Znamya” and “Novyi Mir,” in which The Story of a Life was published. Identified and briefly characterized lifetime printed sources of the text of three chapters of the sixth part of The Story of a Life — “On Low Heat (The Book of Wanderings)”: “The Fourth Strip,” “January Cold” (“The Cold”) and “Night Trains.” The article identifies and characterizes the discrepancies in the named chapters and hypothesizes about the reasons for their occurrence. The novelist, having publ
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Galliano, Emmanuel, and Danielle Alloin. "Gas trapping in extremely massive clusters in NGC 1365." Proceedings of the International Astronomical Union 5, S266 (2009): 399. http://dx.doi.org/10.1017/s1743921309991475.

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AbstractThree radio cm sources in the central star-forming kpc of the closeby barred Seyfert galaxy NGC 1365 are observed. The complete dataset includes VLT infrared J, K, L and N images and spectra. The main observed features include (i) a rising dust continuum towards the mid-infrared (MIR), (ii) bright H emission lines and PAH (polycyclic aromatic hydrocarbon) features, (iii) a bright MIR [Neii] line, and (iv) no detection of MIR [Siv] or [Ariii] lines. For a typical cluster star-formation history and initial mass function, the [Ariii]/[Neii] and [Siv]/[Neii] ratios exhibit an abrupt decrea
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Moreira-Costa, Liliana, António S. Barros, André P. Lourenço, et al. "Exosome-Derived Mediators as Potential Biomarkers for Cardiovascular Diseases: A Network Approach." Proteomes 9, no. 1 (2021): 8. http://dx.doi.org/10.3390/proteomes9010008.

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Cardiovascular diseases (CVDs) are widely recognized as the leading cause of mortality worldwide. Despite the advances in clinical management over the past decades, the underlying pathological mechanisms remain largely unknown. Exosomes have drawn the attention of researchers for their relevance in intercellular communication under both physiological and pathological conditions. These vesicles are suggested as complementary prospective biomarkers of CVDs; however, the role of exosomes in CVDs is still not fully elucidated. Here, we performed a literature search on exosomal biogenesis, characte
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Birnie, Kimberly A., Cecilia M. Prêle, Arthur W. (Bill) Musk, et al. "MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions." Disease Markers 2019 (July 31, 2019): 1–9. http://dx.doi.org/10.1155/2019/8628612.

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Malignant pleural mesothelioma (MPM) is an incurable cancer of the pleura that can be difficult to diagnose. Biomarkers for an easier and/or earlier diagnosis are needed. Approximately 90% of MPM patients develop a pleural effusion (PE). PEs are ideal sources of biomarkers as the fluid would almost always require drainage for diagnostic and/or therapeutic reasons. However, differentiating MPM PE from PE caused by other diseases can be challenging. MicroRNAs are popular biomarkers given their stable expression in tissue and fluid. MicroRNAs have been analysed in PE cytology samples for the diag
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Abrahamyan, Hayk V., and Areg M. Mickaelian. "Investigation of Extragalactic Radio Sources by Cross-Matching of Radio Catalogs." Proceedings of the International Astronomical Union 9, S304 (2013): 100–101. http://dx.doi.org/10.1017/s1743921314003457.

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AbstractTo search for variable radio sources, we used two well-known radio catalogs NVSS and FIRST, both providing fluxes at 1400 MHz. Cross-correlation enabled us to find 556,282 radio sources present in both catalogs. Using the 3σ criteria we distinguished 6,301 variable radio sources, and with certain limitations specified the 260 strongest radio variables. We cross-correlated these 260 sources with other catalogs at different wavelengths (APM, SDSS DR10, VCV-13, BZCAT, 2MASS, and WISE). As a result we obtained photometric data for optical, NIR, MIR and radio ranges for these 260 variable r
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Wang, Feng, Christian Maltecca, Xiaoqiu Wang, Jack Odle, and Lin Xi. "MicroRNA and mRNA Sequencing Analyses Reveal Key Hepatic Metabolic Pathways Responsive to Maternal Malnutrition in Full-Term Fetal Pigs." Current Developments in Nutrition 5, Supplement_2 (2021): 829. http://dx.doi.org/10.1093/cdn/nzab046_126.

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Abstract Objectives Maternal and infant undernutrition is highly prevalent in developing countries, leading to serious fetus/infant mortality, intrauterine growth restriction, stunting, and severe wasting. However, the effects of maternal undernutrition have generally focused on the reduced maternal nutrient supply to the fetus. The potential impairment of fetal metabolic pathways has not been well studied. Methods Pregnant gilts (Landrace x Yorkshire x Duroc) received the NRC gestation diet with (n = 4) or without (n = 4) 50% intake restriction at insemination day and 70% for the following ge
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Shah, Kruti B., Steven D. Chernausek, Lori D. Garman, et al. "Human Milk Exosomal MicroRNA: Associations with Maternal Overweight/Obesity and Infant Body Composition at 1 Month of Life." Nutrients 13, no. 4 (2021): 1091. http://dx.doi.org/10.3390/nu13041091.

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Among all the body fluids, breast milk is one of the richest sources of microRNAs (miRNAs). MiRNAs packaged within the milk exosomes are bioavailable to breastfeeding infants. The role of miRNAs in determining infant growth and the impact of maternal overweight/obesity on human milk (HM) miRNAs is poorly understood. The objectives of this study were to examine the impact of maternal overweight/obesity on select miRNAs (miR-148a, miR-30b, miR-29a, miR-29b, miR-let-7a and miR-32) involved in adipogenesis and glucose metabolism and to examine the relationship of these miRNAs with measures of infa
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Mustafin, R. N. "Molecular genetics of idiopathic pulmonary fibrosis." Vavilov Journal of Genetics and Breeding 26, no. 3 (2022): 308–18. http://dx.doi.org/10.18699/vjgb-22-37.

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Idiopathic pulmonary fibrosis (IPF) is a severe progressive interstitial lung disease with a prevalence of 2 to 29 per 100,000 of the world’s population. Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic instability, mitochondrial dysfunction, loss of proteostasis) are involved in the pathogenesis of IPF. The pathogenesis of IPF consists of TGF-β activation, epithelial-mesenchymal transition, and SIRT7 expression decrease. Genetic studies have shown a role of mutations and polymorphisms in mucin genes (MUC5B), in the genes responsible for the
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Zhao, Xin. "Confucius Institute and the Russkiy Mir Foundation in the Context of Globalization: a Comparative Analysis." Общество: философия, история, культура, no. 9 (September 25, 2020): 143–47. http://dx.doi.org/10.24158/fik.2020.9.25.

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The study discusses that the Confucius Institute of China and the Russkiy Mir Foundation are develop-ing differently in the context of globalization. The main focus of the research is comparison of the Confucius Institute and the Russkiy Mir Foundation in terms of the purpose of creation, the mode of creation, the management model, sources of fund-ing and the promotion mode. In the end, by compar-ison, the similarities and differences are analyzed, the best examples and experiments are obtained from each other for the further development of the Confucius Institute and Russian centers.
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Aguilar, Susana, Paula García-Olloqui, Lidia Amigo-Morán, et al. "Cardiac Progenitor Cell Exosomal miR-935 Protects against Oxidative Stress." Cells 12, no. 18 (2023): 2300. http://dx.doi.org/10.3390/cells12182300.

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Oxidative stress-induced myocardial apoptosis and necrosis are critically involved in ischemic infarction, and several sources of extracellular vesicles appear to be enriched in therapeutic activities. The central objective was to identify and validate the differential exosome miRNA repertoire in human cardiac progenitor cells (CPC). CPC exosomes were first analyzed by LC-MS/MS and compared by RNAseq with exomes of human mesenchymal stromal cells and human fibroblasts to define their differential exosome miRNA repertoire (exo-miRSEL). Proteomics demonstrated a highly significant representation
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Feng, Weifeng, Huijun Xie, Jiong Li, Xianxin Yan, Shiping Zhu, and Shengyun Sun. "miR-29c Inhibits Renal Interstitial Fibrotic Proliferative Properties through PI3K-AKT Pathway." Applied Bionics and Biomechanics 2022 (August 23, 2022): 1–8. http://dx.doi.org/10.1155/2022/6382323.

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Renal fibrosis, in particular tubulointerstitial fibrosis, which is characterized by an increased extracellular matrix (ECM) formation and development in the interstitium, is the common end pathway for nearly all progressive kidney disorders. One of the sources for this matrix is the epithelial to mesenchymal transition (EMT) from the tabular epithelium. The driving force behind it is some profibrotic growth factors such as transforming growth factor-β (TGF-β) which is responsible for the formation of collagen in renal fibrosis. miR-29c, which is an antifibrotic microRNA, downregulates renal i
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Medina Villaamil, V., I. Santamarina Caínzos, G. Aparicio Gallego, et al. "MicroRNAs as emerging biomarkers for micrometastasis detection in genitourinary tumors." Journal of Clinical Oncology 29, no. 7_suppl (2011): 52. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.52.

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52 Background: MicroRNAs regulate numerous aspects of normal and pathological cellular processes, including cancer. Detection of circulating tumor cells (CTC) may provide diagnostic and prognostic information in genitourinary (GU) tumors. miRNAs may also be considered as potential therapeutic targets when overexpression is associated to pathogenic effect. miRNAs may constitute a promising new class of cancer biomarkers for CTC detection. The aim of this work is identify miRNAs potentially useful for CTC detection in blood samples from patients with GU tumors: bladder, prostate and renal tumors
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Heintz, K. E., J. P. U. Fynbo, E. Høg, et al. "Unidentified quasars among stationary objects from Gaia DR2." Astronomy & Astrophysics 615 (July 2018): L8. http://dx.doi.org/10.1051/0004-6361/201833396.

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Here we apply a technique selecting quasar candidates purely as sources with zero proper motions in the Gaia data release 2 (DR2). We demonstrate that this approach is highly efficient toward high Galactic latitudes with ≲25% contamination from stellar sources. Such a selection technique offers very pure sample completeness, since all cosmological point sources are selected regardless of their intrinsic spectral properties within the limiting magnitude of Gaia. We carry out a pilot-study, defining a sample compiled by including all Gaia-DR2 sources within one degree of the north Galactic pole
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Sussmann, R., A. Ostler, F. Forster, et al. "First intercalibration of column-averaged methane from the Total Carbon Column Observing Network and the Network for the Detection of Atmospheric Composition Change." Atmospheric Measurement Techniques 6, no. 2 (2013): 397–418. http://dx.doi.org/10.5194/amt-6-397-2013.

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Abstract. We present the first intercalibration of dry-air column-averaged mole fractions of methane (XCH4) retrieved from solar Fourier transform infrared (FTIR) measurements of the Network for the Detection of Atmospheric Composition Change (NDACC) in the mid-infrared (MIR) versus near-infrared (NIR) soundings from the Total Carbon Column Observing Network (TCCON). The study uses multi-annual quasi-coincident MIR and NIR measurements from the stations Garmisch, Germany (47.48° N, 11.06° E, 743 m a.s.l.), and Wollongong, Australia (34.41° S, 150.88° E, 30 m a.s.l.). Direct comparison of the r
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